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    November 2012

    Chemicals Evaluated for Carcinogenic PotentialOffice of Pesticide Programs

    U.S. Environmental Protection Agency

    BACKGROUND

    What is this list?The following list provides an overview of pesticide chemicals evaluated for carcinogenicpotential by EPAs Pesticide Program through October 2012. The evaluation of many of thesechemicals is an ongoing process. Therefore, the information in this list may be subject tochange as new and/or additional data are submitted to EPA. This list will be updated annually.

    How should the information provided in this list be used?Although this list is available to the public, note that the list represents only the potentialcarcinogenicity hazard for the chemical with no consideration of exposure information. This listis not intended to be used independent of the full risk assessment for the chemical. WhenEPA completes a risk assessment on a pesticide, a variety of toxicity information, includingpotential for noncancer effects (e.g., neurotoxicity, developmental and reproductive toxicity,immunotoxicity, etc) and carcinogenicity, are considered in determining whether to register apesticide and what requirements for use of the pesticide need to be in place to protect humanhealth. The simple fact of being listed here does not imply that the pesticide poses asignificant cancer hazard to the public from use

    What does the report date mean?The date included in the list for each chemical is the date of the most recent review of potentialcarcinogenicity hazard for that chemical. This date provides a key as to which set of cancerguidelines were used in the review. Note that the classification of potential carcinogenicity

    generally is not reevaluated unless new data are submitted.

    How does EPA review pesticides for potential carcinogenici ty?In evaluating and describing the potential carcinogenicity of a pesticide, EPAs PesticideProgram follows the Agencys Guidelines for Carcinogen Risk Assessment (seehttp://epa.gov/cancerguidelines/for more information). The Health Effects Division of thePesticide Program performs an independent review of all the available evidence to determinethe carcinogenic potential of pesticides.

    The results of the independent review are peer-reviewed by the Cancer Assessment ReviewCommittee. This committee recommends a descriptor (e.g., likely to be carcinogenic to

    humans, not likely to be carcinogenic to humans, suggestive evidence of carcinogenicpotential) to convey the cancer hazard potential of the compound. This descriptor is alsoreferred to as the cancer classification. The evidence for the human cancer potential and theextent to which a person might be exposed (how much time and to what quantity of thepesticide) will determine how the Agency regulates the pesticide. In some cases, EPA mayrequest a review by the FIFRA Scientific Advisory Panel.

    http://epa.gov/cancerguidelines/http://epa.gov/cancerguidelines/http://epa.gov/cancerguidelines/
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    What does EPA consider in its review of cancer risk?In determining the cancer-causing potential of a chemical, EPA considers the full range ofavailable evidence. This information includes

    laboratory animal findings, metabolism studies,

    structural relationships with other carcinogens, and if available, mode of carcinogenic action information and epidemiologic findings in

    humans.

    All of the information is considered in a weight-of-the-evidence approach. In this weight-of-evidence evaluation, EPA undertakes a critical analysis of each available study to determineits quality and reliability. Then the entire body of evidence is integrated and examined forconsistency (repeatability of findings in studies), cohesiveness (a logical pattern of responses),and for biological plausibility (i.e., are the observed findings consistent with currentunderstanding of carcinogenic processes). How the Agency determines the cancer potential ofa compound can be found at: http://epa.gov/cancerguidelines/

    Most of the cancer determinations for pesticides are largely based on laboratory animal studiesbecause, under its statutory authority, EPA requires registrants to submit an extensive range oflaboratory studies on pesticides including long-term rodent cancer studies(http://www.epa.gov/pesticides/regulating/data_requirements.htm). The findings in laboratoryanimals are generally assumed to be relevant to humans unless there is evidence to thecontrary. When human information is available, EPA would consider that information (forexample seehttp://www.epa.gov/pesticides/health/ag-health.html.)

    When does EPA review pesticides for potential carcinogenici ty?EPA reviews studies submitted when a pesticide is proposed for registration. Studies arerequired in two species (mice and rats) and two sexes (males and females), as well as abattery of mutagenicity assays. These studies are required for all pesticides used on food andsome non-food pesticides that could lead to long-term exposures in humans. In future reviewsof the pesticide, the cancer classification may be reevaluated if new studies have beensubmitted.

    All ex isting pesticide tolerances that were in place as of August 1996 were re-assessed fortheir human health and environmental risks by August 2006 as required by the Food QualityProtection Act of 1996. However, if there was no new information on carcinogenicity, thecompound was not re-evaluated simply to determine how it would be described under the 2005cancer guidelines.

    How have the Agencys cancer assessment guidelines changed?There have been a number of different documents issued by the Agency for cancerevaluation.

    In 1976, EPA issued its first set of principles and interim procedures to guide evaluation ofhuman cancer potential.

    In 1986, EPA issued guidance, which included a letter system (A-E) for designating degree ofcarcinogenic potential.

    o In the 1986 guidelines, hazard identification and the weight-of evidence process focusedon tumor findings.

    http://www.epa.gov/pesticides/regulating/data_requirements.htmhttp://www.epa.gov/pesticides/regulating/data_requirements.htmhttp://www.epa.gov/pesticides/regulating/data_requirements.htmhttp://www.epa.gov/pesticides/health/ag-health.htmlhttp://www.epa.gov/pesticides/health/ag-health.htmlhttp://www.epa.gov/pesticides/health/ag-health.htmlhttp://www.epa.gov/pesticides/health/ag-health.htmlhttp://www.epa.gov/pesticides/regulating/data_requirements.htm
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    o Seehttp://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htmfor a detailed description of this classification system.

    In 1996, EPA released Proposed Guidelines for Carcinogen Risk Assessment, which used aweight of evidence narrative and standardized descriptors to replace the 1986 alphanumericclassification to classify carcinogenic potential.

    o In the 1996 proposal, emphasis was placed on available mode of carcinogenic actioninformation and discussing characterization of hazard, dose-response, and exposure

    assessments.o The hazard and weight of evidence process embraced an analysis of all relevant

    biological information and emphasized understanding the agent's mode of action inproducing tumors to reduce the uncertainty in describing the likelihood of harm.

    o See 1996 -http://www.epa.gov/raf/publications/pdfs/propcra_1996.pdf In 1999, EPA issued a revised version of its 1996 proposal that responded to public and peer

    review comments, which included:o a framework approach to evaluate the mode of action in the assessment of potential

    carcinogenesis.o See-http://epa.gov/raf/publications/pdfs/CANCER_GLS.PDF

    In March, 2005, EPA released its final Guidelines for Carcinogen Risk Assessment (EPA/630/P-03/001B).These guidelines represent the culmination of a long development process, replacing

    EPAs original cancer risk assessment guidelines (1986) and its interim final guidelines (1999).Key changes included:o Five weight of evidence descriptors chosen for use in narratives (Carcinogenic to

    Humans, Likely to Be Carcinogenic to Humans, Suggestive Evidence of CarcinogenicPotential, Inadequate Information to Assess Carcinogenic Potential, and Not Likely toBe Carcinogenic to Humans.)

    o Emphasis on analysis of data will precede use of defaultso Improved guidance on modeling and expanded discussions of sensitive subpopulations

    including children (supplemental guidance)o Seehttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-

    05.PDF

    Why are there several different cancer classifications in the lis t?As discussed above, EPAs guidelines for evaluating the potential carcinogenicity of chemicalshave been updated over the years to reflect increase transparency in describing the cancerpotential of a compound and to reflect the understanding of ways chemicals may causecancer.

    Not all pesticides have been evaluated under EPAs 2005 Cancer Guidelines. Agency policystates that for risk assessments that were completed before issuance of the 2005 Guidelines,the need for a re-assessment should be determined on a case-by-case basis by the programand that the existing assessment should continue to be considered scientifically sound basedon the guidance used when the assessment was completed

    (http://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdf)

    How can I find the basis of EPAs decision regarding the carcinogenici ty of a pesticide?The Reregistration Eligibility Decision for each pesticide contains a discussion of the availabledata and information used in the human health and environmental risk assessments, whichincludes a description of the evidence used to determine the cancer potential of the chemical.Also, the Cancer Assessment Review Committee report is available by requesting it throughthe Freedom of Information Act (FOIA) (link tohttp://www.epa.gov/pesticides/foia/).

    http://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htmhttp://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htmhttp://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htmhttp://www.epa.gov/raf/publications/pdfs/propcra_1996.pdfhttp://www.epa.gov/raf/publications/pdfs/propcra_1996.pdfhttp://www.epa.gov/raf/publications/pdfs/propcra_1996.pdfhttp://epa.gov/raf/publications/pdfs/CANCER_GLS.PDFhttp://epa.gov/raf/publications/pdfs/CANCER_GLS.PDFhttp://epa.gov/raf/publications/pdfs/CANCER_GLS.PDFhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdfhttp://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdfhttp://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdfhttp://www.epa.gov/pesticides/foia/http://www.epa.gov/pesticides/foia/http://www.epa.gov/pesticides/foia/http://www.epa.gov/pesticides/foia/http://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdfhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05.PDFhttp://epa.gov/raf/publications/pdfs/CANCER_GLS.PDFhttp://www.epa.gov/raf/publications/pdfs/propcra_1996.pdfhttp://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htm
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    Page 1 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****1,3Dibromo5,5

    dimethylhydantoin

    77485 6317 NotLikelytoBeCarcinogenicto

    Humans

    8/28/2000

    1,3dichloro5methylhydantoin 89415872 128826 NotLikelytoBeCarcinogenicto

    Humans

    8/28/2000

    2,4 DBA 94826 30801 NotLikelytoBeCarcinogenicto

    Humans

    6/13/2003

    2,4D+Salts&Esters 94757 30001 GroupDNotClassifiableasto

    HumanCarcinogenicity

    1/29/1997

    2,4DCholine(Ethanaminium,2

    hydroxyN,N,Ntrimethyl,2(2,4

    dichlorophenoxy)acetate(1:1)

    1048373723 51505 GroupDNotClassifiableAs

    ToHumanCarcinogenicity

    10/27/2011

    2Benzyl4chlorophenol 120321 62201 GroupCPossibleHuman

    Carcinogen

    9/5/1995

    4aminopyridine 504

    24

    5 69201 Group

    D

    Not

    Classifiable

    As

    ToHumanCarcinogenicity8/6/2007

    Acephate 30560191 103301 GroupCPossibleHuman

    Carcinogen

    5/8/1985

    Acequinocyl 57960197 6329 NotLikelytoBeCarcinogenicto

    Humans

    11/13/2003

    Acetamide 63114772 111101 GroupCPossibleHuman

    Carcinogen

    5/29/1990

    Acetamiprid 135410207 99050 NotLikelytoBeCarcinogenicto

    Humans

    12/11/2001

    Acetochlor 34256821 121601 SuggestiveEvidenceof

    Carcinogenic

    Potential

    1/3/2007

    AcibenzolarSmethyl 135158542 61402 NotLikelytoBeCarcinogenicto

    Humans

    12/9/1999

    Acifluorfensodium 62476599 114402 LikelytobeCarcinogenictoHumans

    atHighDosesNotLikelytobe

    CarcinogenictoHumansatLow

    Doses

    7/9/2003

    Acrinathrin 101007061 129141 GroupDNotClassifiableasto

    HumanCarcinogenicity

    7/15/1996

    ADBAC 68424851 69105 NotLikelytoBeCarcinogenicto

    Humans

    12/8/1999

    Alachlor 15972608 90501 LikelytobeCarcinogenictoHumans

    (HighDoses);NotLikelytobe

    CarcinogenictoHumans(LowDoses)

    6/27/1997

    Aldicarb 116063 98301 GroupEEvidenceofNon

    carcinogenicity forHumans

    7/17/2002

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 1

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    Page 2 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Ametryn 834128 80801 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    9/17/2004

    Amicarbazone 129909906 114004 NotLikelyToBeCarcinogenic

    ToHumans

    8/10/2005

    Aminocyclopyrachlor 858956088,

    858956351,

    858954833,

    124423843,

    1759531

    288008 NotLikelyToBeCarcinogenic

    ToHumans

    11/9/2011

    Aminopyralid 150114719 5100 NotLikelyToBeCarcinogenic

    ToHumans

    7/12/2005

    Amisulbrom 348635870 16330 SuggestiveEvidenceOf

    CarcinogenicPotential

    12/2/2010

    Amitraz 3308961

    1 106201 Suggestive

    Evidence

    of

    CarcinogenicPotential7/18/2006

    Amitrole 61825 4401 NotLikelyToBeCarcinogenicTo

    HumansAtDosesThatDoNotAlter

    RatThyroidHormoneHomeostasis

    5/11/2006

    Aquashade 2650182 110301 NotLikelyToBeCarcinogenic

    ToHumans

    9/27/2005

    Asulam 3337711 106901 GroupCPossibleHuman

    Carcinogen

    12/6/2001

    Atrazine 1912249 80803 NotLikelytobeCarcinogenicto

    Humans

    12/13/2000

    Avermectin(seeEmamectin

    Benzoate)

    65195553 122804 GroupEEvidenceofNon

    carcinogenicity forhumans

    6/27/1996

    Azafenidin 68049832 119016 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    10/18/1999

    Azinphosmethyl 86500 58001 NotLikelytoBeCarcinogenicto

    Humans

    04/20/98

    Azoxystrobin 131860338 128810 NotLikelytoBeCarcinogenicto

    Humans

    1/14/1997

    Bendiocarb 22781233 105201 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    12/16/1997

    Benfluralin 1861401 84301 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    12/27/2001

    Benomyl 17804352 99101 GroupCPossibleHuman

    Carcinogen

    9/21/2000

    Bensulide 741582 9801 NotLikelytoBeCarcinogenicto

    Humans

    6/10/1999

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 2

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    Page 3 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Bentazon 25057890 275200 GroupEEvidenceofNon

    carcinogenicity forHumans

    1/14/1992

    Benthiavalicarbisopropyl 177406

    68

    7 98379 Likely

    to

    be

    Carcinogenic

    to

    Humans

    10/18/2005

    BenzylBenzoate 120514 9501 NotLikelyToBeCarcinogenic

    ToHumans

    6/28/2007

    BetaCyfluthrin 68359375 118831 NotLikelyToBeCarcinogenic

    ToHumans

    1/27/2010

    Bifenazate 149877418 586 NotLikelytoBeCarcinogenicto

    Humans

    8/28/2001

    Bifenthrin 82657043 128825 GroupCPossibleHuman

    Carcinogen

    2/19/2003

    Bioallethrin 584792 4003 SuggestiveEvidenceof

    Carcinogenicity,

    butNot

    Sufficient

    to

    AssessHumanCarcinogenicPotential

    12/02/2003

    BispyrabacSodium 125401925 78906 NotLikelytoBeCarcinogenicto

    Humans

    8/2/2001

    Bitertanol 55179312 117801 NotLikelyToBeCarcinogenic

    ToHumans

    11/30/2005

    Borax 1303964 11102 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/24/1993

    Boricacid 10043353 11001 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/24/1993

    Boron 7440428 128945 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/24/1993

    Boscalid 188425856 128008 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    11/14/2002

    Bromacil 314409 12301 GroupCPossibleHuman

    Carcinogen

    1/13/1993

    Bromoxynil 1689845 35301 GroupCPossibleHuman

    Carcinogen

    03/12/1997

    Bromuconazole 116255482 120503 GroupEEvidenceofNon

    carcinogenicity forhumans

    4/24/1995

    Bronopol 52517 216400 GroupEEvidenceofNon

    carcinogenicity forhumans

    6/12/1995

    Buprofezin 69327760 275100 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    3/15/2000

    Butachlor 23184669 112301 LikelytobeCarcinogenicto

    Humans

    2/24/1999

    Butafenacil 134605644 122004 NotLikelytoBeCarcinogenicto

    Humans

    7/11/2003

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 3

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    Page 4 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Butylate 2008415 41405 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/25/1992

    Cacodylicacid 75

    60

    5 12501 Group

    B

    Probable

    Human

    Carcinogen

    12/14/1999

    Cadusafos 95465999 128864 GroupEEvidenceofNon

    carcinogenicity forhumans

    5/28/1992

    Captafol 2939802 81701 GroupBProbableHuman

    Carcinogen

    5/19/1987

    Captan 133062 81301 Likelyatprolonged,highlevel

    exposures,butnotlikelyatdose

    levelsthatdonotcausecytotoxicity

    andregenerativecellhyperplasia

    9/22/2004

    Carbaryl 63252 56801 LikelytobeCarcinogenicto

    Humans

    2/12/2002

    Carbendazim(MBC) 10605217 128872 GroupCPossibleHuman

    Carcinogen

    4/7/1989

    Carbofuran 1563662 90601 NotLikelytoBeCarcinogenicto

    Humans

    6/17/1997

    Carboxin 5234684 90201 NotLikelytoBeCarcinogenicto

    Humans

    6/5/2003

    Carfentrazoneethyl 128639021 128712 NotLikelytoBeCarcinogenicto

    Humans

    5/16/2001

    Chlorantraniliprole 50000845

    7 90100 Not

    Likely

    To

    Be

    Carcinogenic

    ToHumans3/4/2009

    Chlordimeform 6164983 59701 GroupBProbableHuman

    Carcinogen

    12/20/1985

    Chlorethoxyfos 54593838 129006 GroupDNotClassifiableasto

    HumanCarcinogenicity

    3/9/1995

    Chlorfenapyr 122453730 129093 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    3/18/2003

    ChlorflurenolMethylEster 2536314 98801 NotLikelyToBeCarcinogenic

    ToHumans

    7/10/2006

    Chlorimuronethyl 90982324 128901 NotLikelyToBeCarcinogenic

    ToHumans

    2/5/2009

    Chlormequatchloride 999815 18101 NotLikelyToBeCarcinogenic

    ToHumans

    6/12/2007

    Chloroaniline, p 106478 17203 GroupBProbableHuman

    Carcinogen

    4/27/1995

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 4

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    Page 5 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Chloroneb 2675776 27301 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    12/18/2003

    Chloropicrin 76062 81501 NotLikelyToBeCarcinogenic

    ToHumans

    6/30/2010

    Chlorothalonil 1897456 81901 LikelyToBeCarcinogenicTo

    Humans

    10/20/1997

    Chlorpropham 101213 18301 GroupEEvidenceofNon

    carcinogenicity forhumans

    10/11/1994

    Chlorpyrifos 2921882 59101 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/23/1993

    Chlorpyrifosmethyl 5598

    13

    0 59102 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans5/17/1999

    Chlorsulfuron 64902723 118601 GroupEEvidenceofNon

    carcinogenicity forhumans

    7/17/2002

    Chlorthaldimethyl(DCPA) 1861321 78701 GroupCPossibleHuman

    Carcinogen

    2/10/1995

    Clethodim 99129212 121011 NotLikelyToBeCarcinogenic

    ToHumans

    9/28/2007

    Clodinafoppropargyl 105512069 125203 SuggestiveEvidenceof

    CarcinogenicPotential

    2/8/2006

    Clofencet(MON21200) 82697710 128726 GroupCPossibleHuman

    Carcinogen

    7/23/1996

    Clofentezine 74115245 125501 GroupCPossibleHuman

    Carcinogen

    4/3/1990

    Clomazone 81777891 125401 NotLikelytoBeCarcinogenicto

    Humans

    1/31/2001

    Clopyralid 1702176 117403 NotLikelytoBeCarcinogenicto

    Humans

    12/20/1999

    Cloquintocetmexyl 99607702 700099 NotLikelytoBeCarcinogenicto

    Humans

    8/31/1999

    Cloransulammethyl 147150354 129116 GroupEEvidenceofNon

    carcinogenicity forhumans

    9/30/1997

    Clothianidin 210880925 44309 NotLikelytoBeCarcinogenicto

    Humans

    1/6/2003

    CocamideDiethanolamine 68603429 224600 LikelytobeCarcinogenicto

    Humans

    10/17/2001

    CopperCompounds 20427592 23401 GroupDNotClassifiableAs

    ToHumanCarcinogenicity

    6/13/2006

    Coumaphos 56724 36501 NotLikelytoBeCarcinogenicto

    Humans

    6/25/1999

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 5

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    Page 6 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Cresol,pChlorom 59507 64206 GroupDNotClassifiableasto

    HumanCarcinogenicity

    11/28/1995

    Cryolite 15096523 75101 GroupDNotClassifiableasto

    HumanCarcinogenicity

    12/22/1995

    Cumyluron 99485764 27902 SuggestiveEvidenceOf

    CarcinogenicPotential

    6/11/2008

    Cyanazine 21725462 100101 GroupCPossibleHuman

    Carcinogen

    7/30/1991

    Cyazofamid 120116883 85651 NotLikelyToBeCarcinogenic

    ToHumans

    6/3/2009

    Cyclanilide 113136779 26201 NotLikelytoBeCarcinogenicto

    Humans

    4/9/1997

    Cycloate 113423

    2 41301 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans

    9/25/2003

    Cyflufenamid 180409603 555550 LikelyToBeCarcinogenicTo

    Humans

    6/22/2010

    Cyfluthrin 68359375 128831 NotLikelytoBeCarcinogenicto

    Humans

    5/21/2002

    Cyhalofopbutyl 122008859 82583 NotLikelyToBeCarcinogenic

    ToHumans

    12/20/2007

    Cyhalothrin 68085858 128867 GroupDNotClassifiableasto

    HumanCarcinogenicity

    8/25/1993

    Cyhexatin 13121705 101601 DataAreInadequateforan

    Assessmentof

    Human

    Carcinogenic

    Potential

    4/7/2005

    Cymoxanil 57966957 129106 NotLikelytoBeCarcinogenicto

    Humans

    1/2/2003

    Cypermethrin 52315078 109702 GroupCPossibleHuman

    Carcinogen

    9/27/1988

    Cyproconazole 94361065 128993 NotLikelyToBeCarcinogenicTo

    Humansatdosesthatdonotcausea

    mitogenicresponseintheliver

    12/4/2007

    Cyprodinil 121552612 288202 NotLikelytoBeCarcinogenicto

    Humans

    1/14/1998

    Cyprosulfamide 22166731

    8 877400 Not

    Likely

    To

    Be

    Carcinogenic

    ToHumans2/29/2008

    Cyromazine 66215278 121301 GroupEEvidenceofNon

    carcinogenicity forhumans

    1/6/1995

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 6

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    Page 7 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Daminozide 1596845 35101 GroupBProbableHuman

    Carcinogen

    7/26/1991

    Dantochlor(BCDMH) 118525 28501 NotLikelytoBeCarcinogenicto

    Humans

    8/14/2000

    Dazomet 533744 35602 GroupDNotClassifiableasto

    HumanCarcinogenicity

    12/7/1993

    DEET 134623 80301 GroupDNotClassifiableasto

    HumanCarcinogenicity

    1/4/1996

    Deltamethrin 52918635 97805 NotLikelytoBeCarcinogenicto

    Humans

    9/9/2003

    Desmedipham 13684565 104801 GroupEEvidenceofNon

    carcinogenicity forhumans

    11/20/1995

    Diazinon 333415 57801 NotLikelytoBeCarcinogenicto

    Humans

    6/17/1997

    Dicamba 1918009 29801 GroupDNotClassifiableasto

    HumanCarcinogenicity

    7/29/1996

    Dichlobenil 1194656 27401 GroupCPossibleHuman

    Carcinogen

    7/18/1995

    Dichlormid 37764253 900497 NotLikelyToBeCarcinogenic

    ToHumans

    11/15/2005

    Dichlorobenzamide,2,6 2008584 27402 GroupDNotClassifiableasto

    HumanCarcinogenicity

    11/28/1995

    Dichlorvos 62737 84001 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    3/1/2000

    Diclofopmethyl 51338273 110902 LikelytobeCarcinogenicto

    Humans

    5/24/2000

    Dicloran 99309 31301 SuggestiveEvidenceOf

    CarcinogenicPotential

    09/05/2006

    Diclosulam 145701219 129122 NotLikelytoBeCarcinogenicto

    Humans

    11/9/1999

    Dicofol 115322 10501 GroupCPossibleHuman

    Carcinogen

    6/24/1992

    Dicrotophos 141662 35201 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    10/18/1999

    Didecyldimethylammoniumchloride

    (DDAC)

    7173515 69149 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/11/2000

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 7

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    Page 8 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Difenoconazole 119446683 128847 GroupCPossibleHuman

    Carcinogen

    7/27/1994

    Difenzoquatmethyl

    sulfate 43222

    48

    6 106401 Group

    E

    Evidenceof

    Non

    carcinogenicity forhumans

    5/24/1994

    Diflubenzuron 35367385 108201 GroupEEvidenceofNon

    carcinogenicity forhumans

    4/27/1995

    Diflufenzopyr Sodiium 109293983 5107 NotLikelytoBeCarcinogenicto

    Humans

    10/6/1998

    Dimethenamid 87674688 129051 GroupCPossibleHuman

    Carcinogen

    9/15/1995

    Dimethipin 55290647 118901 GroupCPossibleHuman

    Carcinogen

    1/5/1990

    Dimethoate 60515 35001 GroupCPossibleHuman

    Carcinogen

    3/26/2002

    Dimethomorph 11048870

    5 268800 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans5/13/1998

    Dimethoxane 828002 1001 SuggestiveEvidenceof

    CarcinogenicPotential

    12/21/2000

    Dimethylether 115106 900382 GroupDNotClassifiableasto

    HumanCarcinogenicity

    1/12/1994

    Dimethylhydantoin 16079882 6315 NotLikelytoBeCarcinogenicto

    Humans

    8/28/2000

    Dinocap 39300453 36001 GroupEEvidenceofNon

    carcinogenicity forHumans

    6/22/1994

    Dinoseb 88857 37505 GroupCPossibleHuman

    Carcinogen

    6/19/1986

    Dinotefuran 165252700 44312 NotLikelytoBeCarcinogenicto

    Humans

    3/5/2004

    Diphenylamine 122394 38501 NotLikelytoBeCarcinogenicto

    Humans

    4/1/1997

    Diquatdibromide 85007 32201 GroupEEvidenceofNon

    carcinogenicity forHumans

    5/12/1994

    Disodiummethanearsonate 144218 13802 NotLikelytoBeCarcinogenicto

    Humans

    7/26/2000

    Disulfoton 298044 32501 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/21/1997

    Dithianon 3347226 99201 SuggestiveEvidenceof

    CarcinogenicPotential

    2/23/2006

    Dithiopyr(MON

    7200) 97886

    45

    8 128994 Group

    E

    Evidenceof

    Non

    carcinogenicity forHumans

    5/29/1997

    Diuron 330541 35505 Known/Likely 5/8/1997

    Dodine 2439103 44301 NotLikelyToBeCarcinogenic

    ToHumans

    1/24/2008

    Ecolyst 69089 NotLikelytoBeCarcinogenicto

    Humans

    10/19/1999

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 8

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    Page 9 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    EmamectinBenzoate(Deoxy

    Avermectin)

    137512744 122806 NotLikelytoBeCarcinogenicto

    Humans

    3/19/1998

    Endosulfan 11529

    7 79401 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans

    1/31/2000

    Endothall 145733 38901 NotLikelyToBeCarcinogenic

    ToHumans

    10/23/2008

    Epoxiconazole 106325080,

    133855988

    123909 LikelytobeCarcinogenicto

    Humans

    1/24/2001

    Esbiothrin 28434006 4007 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    12/2/2003

    Esfenvalerate 66230044 109303 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    7/1/1996

    Ethaboxam 162650773 90205 SuggestiveEvidenceof

    CarcinogenicPotential

    3/23/2006

    Ethalfluralin 55283686 113101 GroupCPossibleHuman

    Carcinogen

    9/14/1994

    Ethephon 16672870 99801 GroupDNotClassifiableasto

    HumanCarcinogenicity

    8/15/1994

    Ethion 563122 58401 GroupEEvidenceofNon

    carcinogenicity forhumans

    1/26/1994

    Ethiprole 181587019 5550 SuggestiveEvidenceOf

    CarcinogenicPotential

    10/28/2010

    Ethofumesate 26225796 110601 GroupDNotClassifiableasto

    HumanCarcinogenicity

    2/24/1994

    Ethoprop 13194484 41101 LikelytobeCarcinogenicto

    Humans

    10/7/1998

    Ethyldipropylthiocarbamate

    (EPTC)

    759944 41401 NotLikelytoBeCarcinogenicto

    Humans

    8/31/1999

    Ethylenethiourea(ETU) 96457 600016 GroupBProbableHuman

    Carcinogen

    7/7/1999

    Etofenprox 80844071 128965 Notlikelytobecarcinogenicto

    humansatdosesthatdonotalterrat

    thyroidhormonehomeostasis.

    2/8/2006

    Etoxazole 153233911 107091 NotLikelytoBeCarcinogenicto

    Humans

    8/7/2003

    Famoxadone 131807573 113202 NotLikelytoBeCarcinogenicto

    Humans

    4/16/2003

    Fenamidone 161326347 46679 NotLikelytoBeCarcinogenicto

    Humans

    7/12/2002

    Fenamiphos 22224926 100601 GroupEEvidenceofNon

    carcinogenicity forHumans

    11/23/1993

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 9

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    Page 10 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Fenarimol 60168889 206600 NotLikelytoBeCarcinogenicto

    Humans

    9/5/2001

    Fenazaquin 12092809

    8 44501 Not

    Likely

    To

    Be

    Carcinogenic

    ToHumans

    5/15/2007

    Fenbuconazole 114369436 129011 GroupCPossibleHuman

    Carcinogen

    4/15/1996

    Fenbutatinoxide 13356086 104601 GroupEEvidenceofNon

    carcinogenicity forHumans

    3/2/1993

    Fenhexamide 126833178 90209 NotLikelytoBeCarcinogenicto

    Humans

    3/4/1999

    Fenitrothion 122145 105901 GroupEEvidenceofNon

    carcinogenicity forHumans

    7/13/1993

    Fenoxycarb 72490018 125301 LikelytobeCarcinogenicto

    Humans

    12/22/97

    Fenpropathrin 3951541

    8 127901 Not

    Likely

    to

    be

    Carcinogenic

    to

    Humans12/22/2003

    Fenpropimorph 67564914 121402 NotLikelyToBeCarcinogenic

    ToHumans

    10/19/2005

    Fenpyroximate 134098616 129131 NotLikelytoBeCarcinogenicto

    Humans

    2/19/1997

    Fenthion 55389 53301 GroupEEvidenceofNon

    carcinogenicity forHumans

    3/11/1996

    Fenvalerate 51630581 109301 GroupEEvidenceofNon

    carcinogenicity forHumans

    2/10/2003

    Ferbam 14484641 34801 SeeZiram 4/6/2000

    Fipronil 120068373 129121 GroupCPossibleHuman

    Carcinogen

    7/18/1995

    Flazasulfuron 104040780 119011 NotLikelyToBeCarcinogenic

    ToHumans

    11/16/2005

    Flonicamid 158062670 128016 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    2/24/2005

    Florasulam 145701231 129108 NotLikelyToBeCarcinogenic

    ToHumans

    5/31/2007

    FluazifopPButyl 79241466 122809 NotLikelyToBeCarcinogenic

    ToHumans

    9/19/2008

    Fluazinam 79622596 129098 SuggestiveEvidenceof

    Carcinogenicity,

    but

    Not

    Sufficient

    to

    AssessHumanCarcinogenicPotential

    3/29/2001

    Flubendiamide 272451657 27602 NotLikelyToBeCarcinogenic

    ToHumans

    4/3/2008

    Flucarbazonesodium 181274179 114009 NotLikelytoBeCarcinogenicto

    Humans

    7/19/2000

    Fludioxonil 131341861 71503 GroupDNotClassifiableasto

    HumanCarcinogenicity

    9/19/1996

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 10

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    Page 11 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Flufenacet(Thiaflumide) 142459583 121903 NotLikelytoBeCarcinogenicto

    Humans

    7/16/1997

    Flufenoxuron 10146369

    8 108203 Not

    Likely

    To

    Be

    Carcinogenic

    ToHumans

    8/15/2006

    Flufenpyrethyl 188489078 108853 NotLikelytoBeCarcinogenicto

    Humans

    6/8/2003

    Flumetralin 62924703 123001 NotLikelyToBeCarcinogenic

    ToHumans

    6/21/2007

    Flumetsulam(XRD498) 98967409 129016 GroupEEvidenceofNon

    carcinogenicity forHumans

    3/24/1993

    Flumicloracpentyl 87546187 128724 GroupEEvidenceofNon

    carcinogenicity forHumans

    9/7/1994

    Flumioxazin 103361097,

    141490508

    129034 NotLikelytoBeCarcinogenicto

    Humans

    2/22/2001

    Fluometuron 2164172 35503 GroupCPossibleHuman

    Carcinogen

    8/28/1996

    Fluopicolide 239110157 27412 NotLikelytoBeCarcinogenicto

    Humans

    12/12/2006

    Fluopyram 658066354 80302 LikelyToBeCarcinogenicTo

    Humans

    11/25/09

    Fluoxastrobin 361377299 28869 NotLikelyToBeCarcinogenic

    ToHumans

    1/24/2005

    Fluridone 59756604 112900 GroupEEvidenceofNon

    carcinogenicity forHumans

    7/1/1985

    Fluroxypyr 81406373 128968 NotLikelyToBeCarcinogenic

    ToHumans

    6/26/2003

    Fluroxypyracid

    (see

    also

    PC

    Code

    128968)69377

    81

    7 128959 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans6/26/2003

    Flurprimidol 56425913 125701 NotLikelyToBeCarcinogenic

    ToHumans

    9/29/2005

    Fluthiacetmethyl 117337196 108803 LikelytobeCarcinogenicto

    Humans

    11/20/1998

    Flutolanil 66332965 128975 GroupEEvidenceofNon

    carcinogenicity forHumans

    6/9/1994

    Flutriafol 76674210 128940 NotLikelyToBeCarcinogenic

    ToHumans

    6/1/2009

    Fluxapyroxad 907204313 138009 NotLikelyToBeCarcinogenicTo

    Humans:belowadefineddoserange

    6/9/2011

    Folpet 133073 81601 Notlikelytobecarcinogenicto

    humansatdosesthatdonotcausean

    irritationresponseinthemucosal

    epithelium

    10/13/2010

    Fomesafen 108731700 123802 NotLikelytoBeCarcinogenicto

    Humans

    11/3/2005

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 11

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    Page 12 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Fonofos 944229 41701 GroupEEvidenceofNon

    carcinogenicity forHumans

    11/10/1993

    Forchlorfenuron 6815760

    8 128819 Not

    Likely

    To

    Be

    Carcinogenic

    ToHumans

    3/11/2008

    Formasulfuron 173159574 122020 NotLikelytoBeCarcinogenicto

    Humans

    9/19/2001

    Formetanatehydrochloride 23422539 97301 GroupEEvidenceofNon

    carcinogenicity forHumans

    5/20/1996

    FosetylAl 39148248 123301 NotLikelyToBeCarcinogenic

    ToHumans

    4/22/1999

    Fosthiazate 98886443 129022 NotLikelytoBeCarcinogenicto

    Humans

    9/15/2003

    Furiazole(MON13900) 121776338 911596 LikelytobeCarcinogenicto

    Humans

    10/15/1999

    Furmecyclox 6056805

    0 122601 Group

    B

    Probable

    Human

    Carcinogen7/3/1985

    GammaCyhalothrin 76703623 128807 NotLikelytoBeCarcinogenicto

    Humans

    3/1/2004

    Glufosinateammonium 77182822 128850 NotLikelytoBeCarcinogenicto

    Humans

    5/17/1999

    Glutaraldehyde 111308 43901 NotLikelytoBeCarcinogenicto

    Humans

    5/18/2006

    Glyphosate 1071836 417300 GroupEEvidenceofNon

    carcinogenicity forHumans

    10/30/1991

    Halosulfuronmethyl(MON

    1200)

    100784201 128721 NotLikelytoBeCarcinogenicto

    Humans

    2/26/1998

    Haloxyfopmethyl 690806402 125201 GroupBProbableHuman

    Carcinogen

    9/18/1989

    Hexaconazole 79983714 128925 GroupCPossibleHuman

    Carcinogen

    1/21/1999

    HexavalentChromium(CrVI) 18540299 021101;

    068302

    LikelytobeCarcinogenicto

    Humans

    07/01/09

    Hexazinone 51235042 107201 GroupDNotClassifiableasto

    HumanCarcinogenicity

    7/27/1994

    Hexythiazox 78587050 128849 LikelyToBeCarcinogenicTo

    Humans

    9/2/09

    HOE107892 135590919 811800 NotLikelytoBeCarcinogenicto

    Humans

    11/24/1998

    Hydramethylnon 67485294 118401 GroupCPossibleHuman

    Carcinogen

    3/28/1991

    Hydrogencyanamide 420042 14002 GroupCPossibleHuman

    Carcinogen

    9/15/1993

    Hydroprene 41096462 486300 GroupDNotClassifiableasto

    HumanCarcinogenicity

    6/8/1995

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 12

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    Page 13 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Imazalil 35554440 111901 LikelytobeCarcinogenicto

    Humans

    12/7/1999

    Imazamethabenz 8140585

    8 128842 Group

    D

    Not

    Classifiable

    as

    to

    HumanCarcinogenicity

    6/11/1987

    Imazamox 114311329 129171 NotLikelytoBeCarcinogenicto

    Humans

    2/27/1997

    Imazapic 81334603 129041 GroupEEvidenceofNon

    carcinogenicity forHumans

    9/27/1995

    Imazapyr 81334341 128821 GroupEEvidenceofNon

    carcinogenicity forHumans

    10/5/1995

    ImazaquinAcid 81335377 128848 NotLikelyToBeCarcinogenic

    ToHumans

    10/31/2005

    Imazethapyr 81335775 128922 NotLikelytoBeCarcinogenicto

    Humans

    1/31/2002

    Imazosulfuron 122548338 118602 NotLikelyToBeCarcinogenic

    ToHumans

    3/13/2009

    Imidacloprid 105827789 129099 GroupEEvidenceofNon

    carcinogenicity forHumans

    11/10/1993

    Indaziflam 950782862 80818 NotLikelyToBeCarcinogenic

    ToHumans

    4/22/2010

    Indoxacarb 173584446 67710 NotLikelytoBeCarcinogenicto

    Humans

    7/17/2000

    Iodomethane 74884 11 NotLikelytobeCarcinogenicto

    Humansatdosesthatdonotalterrat

    thyroidhormonehomeostasis

    11/10/2005

    Iodosulfuran 144550367 122021 NotLikelytoBeCarcinogenicto

    Humans

    1/5/2004

    Ipoconazole 125225287 125618 NotLikelyToBeCarcinogenic

    ToHumans

    5/28/2008

    Iprodione 36734197 109801 LikelytobeCarcinogenicto

    Humans

    2/26/1998

    Iprovalicarb 140923177 98359 LikelytobeCarcinogenicto

    Humans

    4/11/2002

    Isofenphos 25311711 109401 GroupEEvidenceofNon

    carcinogenicity forHumans

    1/13/1998

    Isophorone 7859

    1 47401 Group

    C

    PossibleHuman

    Carcinogen9/2/1999

    Isopyrazam 881685581 129222 LikelyToBeCarcinogenicTo

    Humans

    2/2/2011

    Isoxaben 82558507 125851 SuggestiveEvidenceof

    CarcinogenicPotential

    10/7/2008

    Isoxadifenethyl 163520330 823000 NotLikelytoBeCarcinogenicto

    Humans

    1/29/2001

    Isoxaflutole 141112290 123000 LikelytobeCarcinogenicto

    Humans

    09/30/97

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 13

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    Page 14 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Kasugamycin 6980183 230001 NotLikelyToBeCarcinogenic

    ToHumans

    8/17/2005

    Kathon886 55965

    84

    9 107106 Group

    D

    Not

    Classifiable

    as

    to

    HumanCarcinogenicity

    5/18/1995

    KBR3023 119515387 70705 NotLikelytoBeCarcinogenicto

    Humans

    6/9/1999

    Kresoximmethyl 143390890 129111 LikelytobeCarcinogenicto

    Humans

    8/19/1999

    Lactofen 77501634 128888 LikelytobeCarcinogenicinHumans

    atHighDoses.NotLikelytobe

    CarcinogenictoHumansatLow

    Doses

    10/17/2006

    Lambdacyhalothrin 91465086 128897 GroupDNotclassifiableasto

    HumanCarcinogenicity

    9/12/2002

    Lindane 58899 9001 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    11/29/2001

    Linuron 330552 35506 GroupCPossibleHuman

    Carcinogen

    11/20/2001

    Malathion 121755 57701 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    4/28/2000

    Maleichydrazide 123331 51501 GroupEEvidenceofNon

    carcinogenicity

    for

    Humans

    11/10/1993

    Mancozeb 8018017 14504 GroupBProbableHuman

    Carcinogen

    7/7/1999

    Mandipropamid 374726622 36602 NotLikelyToBeCarcinogenic

    ToHumans

    1/21/2009

    Maneb 12427382 14505 GroupBProbableHuman

    Carcinogen

    7/7/1999

    MB46513(photodegradateof

    Fipronil)

    120067836 600050 NotLikelytoBeCarcinogenicto

    Humans

    12/6/2000

    MCPA+Salts 94746 30501 NotLikelytoBeCarcinogenicto

    Humans

    10/29/2003

    MCPBAcid 94815 19201 NotLikelyToBeCarcinogenic

    ToHumans

    10/1/2008

    MecopropP 16484778 129046 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    3/13/2003

    Mefenoxam 70630170 113502 NotLikelytoBeCarcinogenicto

    Humans

    5/17/2000

    Mefluidide 53780340 114001 NotLikelyToBeCarcinogenic

    ToHumans

    5/30/2007

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 14

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    Page 15 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Melamine 108781 777201 GroupDNotClassifiableasto

    HumanCarcinogenicity

    7/21/1993

    Mepanipyrim 110235477 288203 LikelytobeCarcinogenicto

    Humans

    4/20/2004

    MepiquatChloride 24307264 109101 NotLikelyToBeCarcinogenic

    ToHumans

    2/19/2003

    Meptyldinocap (DE126/Dinocap

    II)

    131726 36000 GroupEEvidenceOfNon

    Carcinogenicity ForHumans

    3/17/2009

    Mercaptobenzothiazole,2 149304 51701 GroupCPossibleHuman

    Carcinogen

    11/19/1992

    Mesosulfuron methyl 208465218 122009 NotLikelytoBeCarcinogenicto

    Humans

    3/4/2004

    Mesotrione 10420682

    8 122990 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans

    4/12/2001

    Metaflumizone 139968493 281250 NotLikelyToBeCarcinogenic

    ToHumans

    1/24/2006

    Metalaxyl 57837191 113501 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/20/1994

    Metaldehyde 108623 53001 SuggestiveEvidenceof

    CarcinogenicPotential

    6/23/2005

    Metamsodium 137428 39003 LikelyToBeCarcinogenicTo

    Humans

    5/14/2009

    Metconazole 125116236 125619 NotLikelytoBeCarcinogenicto

    Humans

    4/14/2006

    Methamidophos 1026592

    6 101201 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans02/12/1998

    Methidathion 950378 100301 GroupCPossibleHuman

    Carcinogen

    2/19/1988

    Methiocarb 2032657 100501 GroupDNotClassifiableasto

    HumanCarcinogenicity

    3/2/1993

    Methomyl 16752775 90301 GroupEEvidenceofNon

    carcinogenicity forHumans

    10/25/1996

    Methoxyfenozide 161050584 121027 NotLikelytoBeCarcinogenicto

    Humans

    7/1/1999

    Methylbromide 74839 53201 NotLikelyToBeCarcinogenic

    To

    Humans

    06/20/2001

    Methylisothiocyanate 6317186 68103 Thereareinsufficientdatato

    characterizethecancerriskofMITC.

    4/30/2009

    Methylparathion 298000 53501 NotLikelytoBeCarcinogenicto

    Humans

    12/1/1997

    Metiram 9006422 14601 GroupBProbableHuman

    Carcinogen

    7/7/1999

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 15

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    Page 16 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Metofluthrin 240494706 109709 NotLikelytoBeCarcinogenicto

    Humansatdosesthatdonotresultin

    amitogenic

    response.

    7/26/2007

    Metolachlor 51218452 108801 GroupCPossibleHuman

    Carcinogen

    11/16/1994

    Metrafenone 220899036 325 SuggestiveEvidenceof

    CarcinogenicPotential

    7/6/2006

    Metribuzin 21087649 101101 GroupDNotClassifiableasto

    HumanCarcinogenicity

    5/16/1995

    Metsulfuronmethyl 74223646 122010 NotLikelytoBeCarcinogenicto

    Humans

    3/14/2002

    Mevinphos 7786347 15801 NotLikelyToBeCarcinogenic

    ToHumans

    5/17/2000

    MGK264 113484 57001 GroupCPossibleHuman

    Carcinogen

    6/7/1995

    MGKReplellent326 136458 47201 GroupBProbableHuman

    Carcinogen

    11/12/2002

    Molinate 2212671 41402 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    12/14/2000

    MON4660 71526073 600046 LikelytobeCarcinogenicto

    Humans

    12/9/1999

    Monosodium acidmethanearsonate

    (MMA)

    2163806 13803 NotLikelytoBeCarcinogenicto

    Humans

    7/26/2000

    MSMAcalcium salt 5902954 13806 NotLikelytoBeCarcinogenicto

    Humans

    12/14/2000

    Myclobutanil 88671890 128857 GroupEEvidenceofNon

    carcinogenicity forHumans

    6/16/1994

    NAApotassiumsalt 15165794 56003 NotLikelyToBeCarcinogenic

    ToHumans

    3/14/2012

    Naled 300765 34401 GroupEEvidenceofNon

    carcinogenicity forHumans

    8/31/1994

    Napropamide 15299997 103001 NotLikelyToBeCarcinogenic

    ToHumans

    7/7/2005

    NaptalamSodiumSalt 132672 30703 GroupDNotClassifiableasto

    HumanCarcinogenicity

    9/7/1994

    NapthaleneAcetates 2122705 56008 NotLikelyToBeCarcinogenic

    ToHumans

    3/5/2009

    Nicosulfuron 111991094 129008 GroupEEvidenceofNon

    carcinogenicity forHumans

    9/1/1998

    Nitrapyrin 1929824 69203 SuggestiveEvidenceOf

    CarcinogenicPotential

    3/1/2012

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 16

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    Page 17 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Norflurazon 27314132 105801 GroupCPossibleHuman

    Carcinogen

    11/2/1990

    Novaluron 11671446

    6 124002 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans

    2/4/2004

    Orthophenylphenol(seealsoPC

    064104)

    90437 64103 NotLikelytoBeCarcinogenicto

    Humans(quantification ofcancerrisk

    isnotrequiredsincetheNOAEL

    selectedforthechronicReference

    Dosewouldaddresstheconcernsfor

    theprecursoreventsleadingto

    development ofbladderandliver

    tumors)

    10/12/2005

    Orthophenylphenol,Sodiumsalt

    (seealsoPC064103)

    132274 64104 NotLikelytoBeCarcinogenicto

    Humans(quantification ofcancerrisk

    isnotrequiredsincetheNOAEL

    selectedforthechronicReference

    Dosewouldaddresstheconcernsfor

    theprecursoreventsleadingto

    development ofbladderandliver

    tumors)

    10/12/2005

    Orthosulfamuron 213464778 108209 SuggestiveEvidenceof

    Carcinogenic

    Potential

    10/26/2006

    Oryzalin 19044883 104201 LikelytobeCarcinogenicto

    Humans

    6/25/2003

    Oxadiazon 19666309 109001 LikelyToBeCarcinogenicTo

    Humans

    5/1/2001

    Oxadixyl 77732093 126701 GroupCPossibleHuman

    Carcinogen

    1/4/1989

    Oxamyl 23135220 103801 GroupEEvidenceofNon

    carcinogenicity forHumans

    11/5/1996

    Oxydemetonmethyl 301122 58702 NotLikelytoBeCarcinogenicto

    Humans

    7/24/1997

    Oxyfluorfen 42874033 111601 LikelyToBeCarcinogenicTo

    Humans

    4/20/2010

    Oxytetracycline 2058460 6308 GroupDNotClassifiableasto

    HumanCarcinogenicity

    12/18/1992

    Oxythioquinox 2439012 54101 GroupBProbableHuman

    Carcinogen

    2/15/1996

    Paclobutrazol 76738620 125601 GroupDNotClassifiableasto

    HumanCarcinogenicity

    6/23/1994

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 17

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    Page 18 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Paradichlorobenzene 106467 61501 NotLikelyToBeCarcinogenic

    ToHumans

    6/5/2007

    Paranitrophenol 10002

    7 56301 Group

    D

    Not

    Classifiable

    as

    to

    HumanCarcinogenicity

    5/14/1996

    Paraquatdichloride 1910425 61601 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/19/2000

    Parathion,ethyl 56382 57501 GroupCPossibleHuman

    Carcinogen

    9/11/1991

    Pebulate 1114712 41403 NotLikelytoBeCarcinogenicto

    Humans

    12/7/1998

    Pendimethalin 40487421 108501 GroupCPossibleHuman

    Carcinogen

    7/24/1992

    Penflufen 49479367

    8 100249 Suggestive

    Evidence

    Of

    CarcinogenicPotential3/30/2011

    Penoxulam 219714962 119031 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    3/24/2004

    Pentachloronitrobenzene(PCNB) 82688 56502 GroupCPossibleHuman

    Carcinogen

    12/18/1992

    Pentachlorophenol 87865 63001 GroupBProbableHuman

    Carcinogen

    1/3/1991

    Penthiopyrad 183675823 90112 SuggestiveEvidenceOf

    CarcinogenicPotential

    10/18/2011

    Permethrin 52645531 109701 LikelytobeCarcinogenicto

    Humans

    10/23/2002

    Phenmedipham 13684634 98701 GroupDNotClassifiableasto

    HumanCarcinogenicity

    4/28/1993

    PHMB 32289580 111801 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    07/16/2003

    Phorate 298022 57201 GroupEEvidenceofNon

    carcinogenicity forHumans

    12/30/1993

    Phosalone 2310170 97701 NotLikelytoBeCarcinogenicto

    Humans

    8/12/1999

    Phosmet 73211

    6 59201 Suggestive

    Evidence

    of

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    10/27/1999

    Phosphamidon 13171216 18201 GroupCPossibleHuman

    Carcinogen

    5/31/1989

    Phostebupirim 96182535 129086 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/27/1993

    PicloramAcid 1918021 5101 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/1/1994

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 18

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    Page 19 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    PicloramAcidEthylhexylEster 26952205 5103 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/1/1994

    PicloramAcid

    Potassium

    Salt 2545

    60

    0 5104 Group

    E

    Evidenceof

    Non

    carcinogenicity forHumans

    4/1/1994

    PicloramAcid

    TriisopropanolamineSalt

    6753475 5102 GroupEEvidenceofNon

    carcinogenicity forHumans

    4/1/1994

    Picoxystrobin 117428225 129200 SuggestiveEvidenceOf

    CarcinogenicPotential

    11/15/11

    Pinoxaden 243973208 147500 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    5/18/2005

    Piperonylbutoxide 51036 67501 GroupCPossibleHuman

    Carcinogen

    6/7/1995

    Pirimicarb 23103982 106101 LikelytobeCarcinogenicto

    Humans

    7/13/2005

    Pirimiphosmethyl 29232937 108102 CannotBeDetermined 1/29/1998

    PolymericBetaine 214710346 103679 InadequateInformationto

    AssessCarcinogenicPotential

    10/3/2006

    Potassiumdichromate 7778509 68302 SeeHexavalentChromium

    (CrVI)

    07/01/2009

    Prallethrin 23031369 128722 NotLikelytoBeCarcinogenicto

    Humans

    6/27/2003

    Primisulfuronmethyl 86209510 128973 GroupDNotClassifiableasto

    HumanCarcinogenicity

    5/3/1990

    Prochloraz 6774709

    5 128851 Group

    C

    PossibleHuman

    Carcinogen

    7/1/1988

    Procymidone 32809168 129044 GroupBProbableHuman

    Carcinogen

    4/5/1991

    Prodiamine 29091212 110201 GroupCPossibleHuman

    Carcinogen

    6/10/1991

    Profenofos 41198087 111401 GroupEEvidenceofNon

    carcinogenicity forHumans

    2/6/1996

    Prohexadione 127277536 112600 NotLikelytoBeCarcinogenicto

    Humans

    4/14/2000

    Prometon 1610180 80804 GroupDNotClassifiableasto

    HumanCarcinogenicity

    11/25/1992

    Prometryn 7287196 80805 GroupEEvidenceofNon

    carcinogenicity forHumans

    7/26/1994

    Pronamide 23950585 101701 GroupBProbableHuman

    Carcinogen

    12/10/2001

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 19

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    Page 20 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Propachlor 1918167 19101 LikelytobeCarcinogenicto

    Humans

    10/16/1997

    Propamocarb hydrochloride 25606411 119302 NotLikelyToBeCarcinogenic

    ToHumans

    5/31/2000

    Propanil 709988 28201 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    6/19/2001

    Propargite 2312358 97601 GroupBProbableHuman

    Carcinogen

    7/23/1992

    Propazine 139402 80808 NotLikelytoBeCarcinogenicto

    Humans

    12/8/2005

    Propetamphos 31218834 113601 NotLikelytoBeCarcinogenicto

    Humans

    10/31/1998

    Propiconazole 60207901 122101 GroupCPossibleHuman

    Carcinogen

    9/11/1992

    Propoxur 114261 47802 GroupBProbableHuman

    Carcinogen

    6/17/1996

    PropoxycarbazoneSodium 181274157 122019 NotLikelytoBeCarcinogenicto

    Humans

    4/6/2004

    Prosulfuron 94125345 129031 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    1/24/2000

    Prothioconazole 178928706 113961 NotLikelyToBeCarcinogenic

    ToHumans

    12/31/2007

    Pymetrozine 123312890 101103 LikelytobeCarcinogenicto

    Humans

    9/22/1999

    Pyraclostrobin 175013180 99100 NotLikelytoBeCarcinogenicto

    Humans

    2/15/2007

    Pyraflufenethyl 129630199 30090 LikelytobeCarcinogenicto

    Humans

    10/8/2002

    Pyrasulfotole 365400119 692 SuggestiveEvidenceOf

    CarcinogenicPotential

    5/17/2007

    Pyrazon 1698608 69601 NotLikelyToBeCarcinogenic

    ToHumans

    7/28/2005

    Pyrethrins 8003347 69001 NotLikelyToBeCarcinogenicTo

    Humansatdosesthatdonotcause

    mitogenicrepsonseinthelivercell

    proliferation

    2/14/2008

    Pyridaben 96489713 129105 GroupEEvidenceofNon

    carcinogenicity forHumans

    5/11/1994

    Pyridalyl 179101816 295149 NotLikelyToBeCarcinogenic

    ToHumans

    08/03/2004

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 20

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    Page 21 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Pyridate 55512339 128834 NotLikelyToBeCarcinogenic

    ToHumans

    1/24/2000

    Pyrifluquinazon 33745827

    2 555555 Not

    Likely

    To

    Be

    Carcinogenic

    To

    Humansatlevelsthatdonotalter

    rodenthormonehomeostasis

    6/21/2012

    Pyrimethanil 53112280 288201 GroupCPossibleHuman

    Carcinogen

    2/11/1997

    Pyriofenone 688046619 28828 NotLikelyToBeCarcinogenic

    ToHumans

    12/14/2011

    Pyriproxyfen 95737681 129032 GroupEEvidenceofNon

    carcinogenicity forHumans

    8/15/1995

    Pyrithiobacsodium 123343168 78905 GroupCPossibleHuman

    Carcinogen

    9/5/1995

    Pyroxasulfone 447399555 90099 NotLikelyToBeCarcinogenicTo

    Humansatdosesbelowthosethat

    causeurinarybladdercalculi

    formationresultingincellular

    damageoftheurinarytract

    05/17/2011

    Pyroxsulam 422556089 108702 NotLikelyToBeCarcinogenic

    ToHumans

    7/12/2007

    Quinchlorac 8408701

    4 128974 Group

    D

    Not

    Classifiable

    as

    to

    HumanCarcinogenicity8/26/1992

    Quinoxyfen 124495187 55459 NotLikelytoBeCarcinogenicto

    Humans

    1/28/2003

    Quizalofopethyl 76578148 128711 GroupDNotClassifiableasto

    HumanCarcinogenicity

    3/17/1988

    Resmethrin 10453868 97801 LikelytobeCarcinogenicto

    Humans

    5/25/2005

    Rimsulfuron 122931480 129009 NotLikelytoBeCarcinogenicto

    Humans

    2/19/1998

    RoteNone 83794 71003 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    10/5/1988

    Saflufenacil(BAS800H) 372137354 118203 NotLikelyToBeCarcinogenic

    ToHumans

    7/22/2009

    SBioallethrin 28434006 4004 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    12/2/2003

    Sedaxane 874967676 129223 LikelyToBeCarcinogenicTo

    Humans

    5/18/2011

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 21

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    Page 22 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Sethoxydim 74051802 121001 NotLikelytoBeCarcinogenicto

    Humans

    3/19/2003

    Simazine 12234

    9 80807 Not

    Likely

    to

    be

    Carcinogenic

    to

    Humans

    4/14/2005

    sMetolachlor 87392129 108800 GroupCPossibleHuman

    Carcinogen

    9/28/2001

    Sodiumbentazon 50723803 103901 GroupEEvidenceOfNon

    Carcinogenicity ForHumans

    01/14/92

    Sodiumomadine 15922788 88004 GroupDNotClassifiableasto

    HumanCarcinogenicity

    5/16/1995

    Spinetoram 187166401+

    187166

    15

    0

    110008 NotLikelyToBeCarcinogenic

    To

    Humans

    9/20/2007

    Spinosad 131929607 110003 NotLikelytoBeCarcinogenicto

    Humans

    7/18/2002

    Spirodiclofen 148477718 124871 LikelytobeCarcinogenicto

    Humans

    6/10/2004

    Spiromesifen 283594901 24875 NotLikelyToBeCarcinogenic

    ToHumans

    5/21/2008

    Spirotetramat 203313251 392201 NotLikelyToBeCarcinogenic

    ToHumans

    3/26/2009

    Spiroxamine 118134308 120759 NotLikelytoBeCarcinogenicto

    Humans

    11/14/2003

    Sulfentrazone 122836355 129081 GroupEEvidenceofNon

    carcinogenicity forHumans

    5/7/1996

    Sulfosate 81591813 128501 GroupEEvidenceofNon

    carcinogenicity forHumans

    7/26/1994

    Sulfosulfuron 141776321 85601 NotLikelytobeCarcinogenicto

    Humansatdosesthatdonotcause

    crystalswithsubsequentcalculi

    formationresultingincellular

    damageoftheurinarytract.

    12/16/2008

    Sulfurylfluoride 2699798 78003 NotLikelytoBeCarcinogenicto

    Humans

    5/24/2001

    Sulprofos 35400432 111501 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    3/26/1996

    Sumithrin 26002802 69005 NotLikelytoBeCarcinogenicto

    Humans

    5/30/2006

    Taufluvalinate 102851069 109302 NotLikelyToBeCarcinogenic

    ToHumans

    9/29/2005

    TCMTB(Busan72) 21564170 35603 GroupCPossibleHuman

    Carcinogen

    8/28/1996

    Tebuconazole 107534963 128997 GroupCPossibleHuman

    Carcinogen

    9/15/1993

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 22

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    Page 23 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Tebufenozide 112410238 129026 GroupEEvidenceofNon

    carcinogenicity forHumans

    8/29/1994

    Tebufenpyrad 11916877

    3 90102 Suggestive

    Evidence

    of

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    7/15/2002

    Tebuthiuron 34014181 105501 GroupDNotClassifiableasto

    HumanCarcinogenicity

    3/1/1993

    Tefluthrin 79538322 128912 NotLikelyToBeCarcinogenic

    ToHumans

    5/30/2012

    Telone 542756 29001 GroupBProbableHuman

    Carcinogen

    3/19/2002

    Tembotrione 33510484

    2 12801 Suggestive

    Evidence

    of

    CarcinogenicPotential5/22/2007

    Tepraloxydim 149979419 121005 DataAreInadequateforan

    AssessmentofHumanCarcinogenic

    Potential

    2/27/2001

    Terbacil 5902512 12701 GroupEEvidenceofNon

    carcinogenicity forHumans

    9/30/1994

    Terbufos 13071799 105001 GroupEEvidenceofNon

    carcinogenicity forHumans

    3/9/1994

    Terbuthylazine 5915413 80814 GroupDNotClassifiableasto

    HumanCarcinogenicity

    8/24/1994

    Terbutryn 88650

    0 80813 Group

    C

    PossibleHuman

    Carcinogen3/3/1988

    Terrazole 2593159 84701 GroupBProbableHuman

    Carcinogen

    6/29/1999

    Tetrachlorvinphos 961115 83701 LikelytobeCarcinogenicto

    Humans

    3/7/2002

    Tetraconazole 112281773 120603 LikelytobeCarcinogenicto

    Humans

    1/11/2000

    Tetramethrin 7696120 69003 GroupCPossibleHuman

    Carcinogen

    12/11/1989

    Thiabendazole 148798 60101 LikelytobeCarcinogenictoHumans

    atHighDoes;NotLikelytobe

    CarcinogenictoHumansatLow

    Doses

    3/8/2002

    Thiacloprid 111988499 14019 LikelytobeCarcinogenicto

    Humans

    10/31/2012

    Thiamethoxam 153719234 60109 NotLikelytoBeCarcinogenicto

    Humans

    6/13/2005

    Thiazopyr(MON13200) 117718602 129100 SuggestiveEvidenceOf

    CarcinogenicPotential

    12/6/2007

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 23

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    Page 24 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Thidiazuron 51707552 120301 NotLikelyToBeCarcinogenic

    ToHumans

    8/31/2005

    Thiencarbazonemethyl 317815

    83

    1 15804 Not

    Likely

    To

    Be

    Carcinogenic

    To

    Humansatdosesthatdonotcause

    urotheliumcytotoxicity

    2/29/2008

    Thifensulfuron methyl 79277273 128845 NotLikelyToBeCarcinogenic

    ToHumans

    12/12/2006

    Thiobencarb(Bolero) 28249776 108401 GroupDNotClassifiableasto

    HumanCarcinogenicity

    6/10/1996

    Thiocyclamhydrogenoxalate 31895224 128868 GroupDNotClassifiableasto

    HumanCarcinogenicity

    9/15/1994

    Thiodicarb 5966926

    0 114501 Group

    B

    Probable

    Human

    Carcinogen6/10/1996

    Thiophanatemethyl 23564058 102001 LikelytobeCarcinogenicto

    Humans

    8/24/1999

    Thiram 137268 79801 NotLikelytoBeCarcinogenicto

    Humans

    4/14/2003

    Tolyfluanid 731271 309200 LikelytobeCarcinogenicto

    Humans

    6/18/2002

    Topramezone 210631688 123009 NotLikelytobeCarcinogenicto

    HumansatDosesthatDoNotAlter

    RatThyroidHormoneHomeostasis

    5/19/2005

    Tralkoxydim 87820880 121000 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    6/30/2004

    Triadimefon 43121433 109901 GroupCPossibleHuman

    Carcinogen

    12/4/1996

    Triadimenol 55219653 127201 GroupCPossibleHuman

    Carcinogen

    1/29/1988

    Triallate 2303175 78802 GroupCPossibleHuman

    Carcinogen

    1/12/1994

    Triasulfuron 82097505 128969 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    2/27/1991

    Triazamate 112143825 128100 NotLikelytoBeCarcinogenicto

    Humans

    12/1/1997

    Tribenuronmethyl 101200480 128887 GroupCPossibleHuman

    Carcinogen

    7/14/1989

    Tribufos 78488 74801 LikelytobeCarcinogenictoHumans

    (HighDoses);NotLikelytobe

    CarcinogenictoHumans(LowDoses)

    5/22/1997

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 24

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    28/29

    Page 25 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Tributyltinmaleate 14275571 83118 GroupDNotClassifiableAs

    ToHumanCarcinogenicity

    3/31/2005

    Trichlorfon 52686 57901 LikelytobeCarcinogenictoHumans

    (HighDoses),NotLikelytobe

    CarcinogenictoHumans(LowDoses)

    7/15/1999

    Triclopyr 55335063 116001 GroupDNotClassifiableasto

    HumanCarcinogenicity

    5/9/1996

    Triclosan 3380345 54901 NotLikelyToBeCarcinogenic

    ToHumans

    1/4/2008

    Tridiphane 58138082 123901 GroupCPossibleHuman

    Carcinogen

    4/22/1986

    Trifloxystrobin 14151721

    7 129112 Not

    Likely

    to

    Be

    Carcinogenic

    to

    Humans6/16/1999

    Trifloxysulfuron 290332104 119009 NotLikelytoBeCarcinogenicto

    Humans

    7/22/2003

    Triflumizole 68694111 128879 GroupEEvidenceofNon

    carcinogenicity forHumans

    8/10/1993

    Trifluralin 1582098 36101 GroupCPossibleHuman

    Carcinogen

    4/11/1986

    Triflusulfuronmethyl 126535157 129002 GroupCPossibleHuman

    Carcinogen

    5/28/1996

    Triforine 26644462 107901 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHumanCarcinogenicPotential

    6/29/2004

    TrinexapacEthyl 95266403 112602 NotLikelyToBeCarcinogenic

    ToHumans

    9/5/2008

    Triphenyltinhydroxide(TPTH) 76879 83601 GroupBProbableHuman

    Carcinogen

    5/24/1990

    Triticonazole 131983727 125620 NotLikelytobeCarcinogenicto

    Humans

    6/15/2006

    Troysanpolyphase(IPBC) 55406536 107801 NotLikelytoBeCarcinogenicto

    Humans

    12/4/1996

    UDMH 57147 600018 GroupBProbableHuman

    Carcinogen

    7/26/1991

    UMP488(PAL6000) 111578326 129025 GroupEEvidenceofNon

    carcinogenicity

    forHumans

    5/6/1994

    Uniconazole 83657221 128976 GroupCPossibleHuman

    Carcinogen

    10/11/1990

    Vinclozolin 50471448 113201 GroupCPossibleHuman

    Carcinogen

    6/20/2000

    ZetaCypermethrin 52315078 129064 GroupCPossibleHuman

    Carcinogen

    9/27/1988

    For information about future review of these pesticides, see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/ 25

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    Page 26 Annual Cancer Report November 2012

    CHEMICAL CAS NO.* PC

    CODE**

    CANCER CLASSIFICATION*** REPORT

    DATE****

    Chemicals Evaluated for Carcinogenic Potential

    Office of Pesticide ProgramsU.S. Environmental Protection Agency

    Ziram 137304 34805 SuggestiveEvidenceof

    Carcinogenicity, butNotSufficientto

    AssessHuman

    Carcinogenic

    Potential

    2/6/2003

    Zoxamide 156052685 101702 NotLikelytoBeCarcinogenicto

    Humans

    2/7/2001

    ****Report: Date of the Carcinogen Assessment Review Committee (CARC) report. The CARC report date does not necessarily

    reflect the date of the pesticide risk assessment. For example, all existing pesticide tolerances that were in place as of August

    1996 were re-assessed for their health risks by August 2006 as required by the Food Quality Protection Act, and if there was no

    new information on carcinogenicity, the compound was not re-evaluated by the CARC.

    For information about future review of these pesticides see the Registration Review schedule/status at

    http://www.epa.gov/oppsrrd1/registration_review/

    *CAS No.: a chemical identifier designated by the Chemical Abstracts Service

    **PC Code: a unique chemical identifier used by the Office of Pesticide Programs

    ***Cancer Classification: Simple descriptors used to express conclusions regarding the carcinogenic hazard potential of a

    chemical based on all relevant information, which is usually laboratory studies. These phases changed over time, as the

    Agency's guidance for carcinogenicity assessment was updated and revised.


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