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Northern California Mortality Reduction
Getting Results to Scale
Dr. Carmen Adams
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 2
Step 1- Identify, Document and Code Sepsis
EARLY
RECOGN I T I ON
Identify at triage if suspected infection and 2 SIRS criteria
To < 96.8 (36.0) or > 100.4 (38.0)HR > 90RR > 20WBC > 12K or < 4K or > 10% bands(OR Altered LOC)
CBC, Lactate, BC
Consider IV fluids and ABX
SBP ≤ 90?
yesno
Lactate high?
20 ml/kg fluid bolus
2-3.9 IV fluidsConsider ABX
Repeat lactate in 6 hrs
<2
Document Septic Shock (Time Zero)
Document Septic Shock (Time Zero)
≥ 4
SBP ≤ 90
SBP >90
stop
Suspected Sepsis
Document Severe Sepsis (Time Zero)
Document Severe Sepsis (Time Zero)
Developing a Common Framework for Identification and Treatment
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 3
Step 2: Meet EGDT Goals in 6 Hours
Aggressive fluid resuscitation
Within 1 hr: Start ABX
Within 2 hrs:Central Line Placed
Aggressive fluid resuscitation
Within 1 hr: Start ABX
Within 2 hrs:Central Line Placed
CVP 8-12?
MAP ≥ 65?
ScvO2 ≥70?
8-12
≥ 65
≥ 70
500 to 1000 ml Fluid boluses q 30 min
Norepinephrine
If Hct low, transfuse to 30
<8-12
< 65
<70
<70
Dobutamine
DIRECTED
THERAPY
E A R L Y G O A L
Diagnosis of Severe Sepsis or Septic Shock
Diagnosis of Severe Sepsis or Septic Shock
Lower Lactate
Developing a Common Framework for Identification and Treatment
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 4
Treatment Plan for Severe Sepsis & Shock
Time Zero
1 hour
2 hours
6 hours
6-12 hours
Diagnosis Severe
Sepsis or Septic Shock
ABX startedIV Fluid
Central Line
Placed 1st CVP or SvcO2
MAP
CVP
ScvO2 at Goal
Repeat Lactate is
Lower than First Lactate
Screen all patients at
risk
Bundle Elements
Developing a Common Framework for Identification and Treatment
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 5
Taking Action: (1) May Mortality Summit (2) November Sepsis Summit
Room / Bed # ____________
ADDRESSOGRAPH
EARLY GOAL DIRECTED THERAPY (EGDT) ED AND ICU ORDERSET Page 1 of 4
X Check box to activate an order
Kaiser Foundation Hospital - San Jose
Mark chart: Allergic to ___________________________________________ No Known Allergies Weight _______(kg) Height______ Check if applies: Pregnant Lactating ED ORDERS ICU ORDERS Administer oxygen titrate FiO2 to maintain SpO2 between 90-94%. Notify physician if patient requires over 50% FiO2 via face mask or more than 10% increase in 1 hour to achieve needed goal
___________________, RN ______________(Date/Time)
Insert Foley catheter
___________________, RN ______________(Date/Time)
VITAL SIGNS Measure intake and output hourly
___________________, RN ______________(Date/Time)
Record vital signs (heart rate, blood pressure, respiratory rate, SpO2) per unit standards and as needed
___________________, RN ______________(Date/Time)
Measure central venous pressure (CVP) every 30 minutes until goal has been achieved and for at least 2 hours after goal has been reached, then monitor per unit standards and as needed
___________________, RN ______________(Date/Time)
Monitor mixed venous oxygen saturation (ScvO2) continuously
___________________, RN ______________(Date/Time)
Continue Discontinue
Continue Discontinue
Continue Discontinue
Continue Discontinue
Continue Discontinue
Continue Discontinue
EMERGENCY DEPARTMENT DRAFTED NURSES FLOW SHEET
Date _________________________________ Pg__ of __
Time BP P R T GCS* MAP* FiO2/ CVP RASS* Intervention
Score Character(EMV)
SCVO2SpO2 mm/Hg Score Note actions taken in response to the findings on
the left.
10
10
10
10
10
10
10
10
10
10
10
10
10
10
10
10
10
INTAKE PARENTERAL FLUIDS
Time TYPE AMOUNT Time TYPE AMOUNT Time #SITE
GAUGE TYPE STARTED ABSORBED
TOTALS
Initals Signature/Title Initials Signature/Title Initials Signature/Title
OUTPUT
Pain*
Addressograph
Develop Teams
Tools and Equipment
Adopt Algorithms
Train
Aggressive fluid resuscitation
Within 1 hr: Start ABX
Within 2 hrs:Central Line Placed
Aggressive fluid resuscitation
Within 1 hr: Start ABX
Within 2 hrs:Central Line Placed
CVP 8-12?
MAP ≥ 65?
ScvO2 ≥70?
8-12
≥ 65
≥ 70
500 to 1000 ml Fluid boluses q 30 min
Norepinephrine
If Hct low, transfuse to 30
<8-12
< 65
<70
<70
Dobutamine
DIRECTED
THERAPY
E A R L Y G O A L
Diagnosis of Severe Sepsis or Septic Shock
Diagnosis of Severe Sepsis or Septic Shock
Lower Lactate
Sepsis Care Surgical Care Improvement Program
Lactates Sepsis Implementation
Lactates on ED Blood Cultures Te
am
Trai
ning
Abx
in 1
hr
CL
in 2
hrs
55%
47% 44% 84% 37% 69% 91% 29% 85% 32% 77% 37% 99% 80% 36% 63% 66%
58%
56% 100% 0% 0% 0%
DENOM
Measure
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 6
Sepsis Collaborative and Site Visits
Focus areas of site visits:
• Evidence of Engagement
• Quality of Team’s Functioning
• Interviews with Frontline Staff Members
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 7
The Regional Lens on Environment
Evidence of engagement (sepsis cart, posters, bulletin board)
Regulatory lens (emergency equipment, locked cart)
Observation of patterns of delivery of care
Relevant data is posted and current
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 8
Quality of Team’s Functioning
Participation in Sepsis Multidisciplinary Team meetings
Discuss status of unit ( what’s going well; what could be improved; huddles)
Sepsis Team meeting minutes (barriers are discussed)
Review of performance data
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 9
Interviews with Frontline Staff
Can they verbalize sepsis screening criteriaDo they exhibit awareness of EGDT bundle elements and are they comfortable advocating for this treatmentAre they knowledgeable about performance outcomes in their unitDo they feel valued as a member of this staff
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 10
The ‘Win – Win’ of Site Visits
Attention
Focus
Relationships
Commitment
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 11
Work to Come: Prevention/Detection
Decrease Sepsis Mortality and Morbidity29% of all mortalities
Decrease Sepsis Mortality and Morbidity29% of all mortalities
Sepsis on admission
1385 deaths (24% rate)
AIM Primary Drivers Secondary Driver Initiative
1761 deaths/yr Detection
Treatment Timely ABX, EGDT bundle
16% of POA Sepsis is associated with complication from prior medical or surgical care
386 deaths (47% rate)
DetectionDetection
PreventionPrevention
Sepsis During Hospitalization
6% of all mortalities
Sepsis During Hospitalization
6% of all mortalitiesBSI, VAP, ?HAP, ?
C diff, ?SSI
BSI, VAP, ?HAP, ?C diff, ?SSI
Lactate protocols ? Rounding ? Early
warning
Order lactates!
Connecting to Our Potential
© Copyright Kaiser Permanente, 2009 | For Internal Use Only National Quality Conference | Page 12
More to Come…