Date post: | 18-Dec-2015 |
Category: |
Documents |
View: | 215 times |
Download: | 0 times |
Not to be distributed without permission
Using SciFinder Scholar as a Research ToolHBZ Meeting
Paul Peters, Manager European Marketing
Taken from presentation by Prof. Damon RidleySchool of Chemistry
University of Sydney
NSW 2006 Australia
Not to be distributed without permission
Copyrights
– SciFinder Scholar screens are reproduced with permission of the Chemical Abstracts Service, a Division of the American Chemical Society
– CAPLUS, REGISTRY, and CASREACT data is copyright the American Chemical Society and reproduced with permission
– Data from Journal of the American Chemical Society is copyright the American Chemical Society and reproduced with permission
– Data from Angewandte Chemie International Edition is copyright John Wiley & Sons Inc. and reproduced with permission
Not to be distributed without permission
Searching for information
• What sources do you currently use?
• Why have you chosen these sources?
• How do they compare with other sources?– in content
– in ease of use
– in search opportunities
– in quality!
– (in price)
• What information are you missing?
• Search skills?
Not to be distributed without permission
Searching the literature
• Is very complicated!
• The “text book” approach for electronic information retrieval is to– start with general searches
– examine initial results
– modify search
• This helps:– overcome some of the difficulties relating to different terminologies (used by authors and database producers)
– alert us to new opportunities
• So, it helps to ….
Not to be distributed without permission
In the laboratory Information retrieval
Know the subject Know the content and coverage of databases and of search options
Conduct experiment Run initial search
Observe/understandresults
Examine/understand answer sets
Revise experiment Explore alternative search options
…apply Scientific Method to Information Retrieval!
Not to be distributed without permission
Databases in SciFinder Scholar
• Over 23.5M bibliographic records (CAPLUS) – from over 9,000 serials
– from over 35 patent issuing organizations
– from 1907
– updated daily
• Over 13.7M bibliographic records (MEDLINE)– from over 4,300 serials
– from 1958
– updated 4 times weekly
• Over 61M substances/sequences from 1907 (REGISTRY)
• Over 7.5M chemical reactions from “1974*“ (CASREACT)
• Inventory Information (CHEMLIST)
• Commercially available substances (CHEMCATS)
* some earlier information available and more is being added
Not to be distributed without permission
Search opportunities in SciFinder Scholar
• SciFinder Scholar has over 50 search options including:
– Topics
– Authors
– Companies
– Substances• by name
• by formula
• by structure
• by substructure
– Citations
– Reactions
• SciFinder Scholar has an unique interface, and the key to its use as a research tool is to understand the Analyze/Refine and Get Related options!
Not to be distributed without permission
Bibliographic Database Record
The record we search consists of author terms...
The Chemical Abstracts Service bibliographic database
Database
Content
Not to be distributed without permission
Bibliographic Database Record
...and terms added by the indexers ...
this is how substances are indexed!
these are the ‘roles’ for substances
Indexing is very important!
Database
Content
CA Section Title
Not to be distributed without permission
CAPLUS Record
Abstract written by
Indexer!
Reaction
Search
Information on reactions
in title and abstract
Not to be distributed without permission
CAPLUS Record
Reaction
Search
Information on reactions in indexing
… all in CAPLUS!
Not to be distributed without permission
CASREACT Record
• All the atoms, bonds, functional groups in starting material and products are included in the database record
Reaction
Search
Not to be distributed without permission
Searching Bibliographic Databases
• We are searching entries written by authors and by indexers. It helps if we try to think how they may have written about the topic of interest to us.
• (It helps if authors remember that most people will find articles through electronic databases, so write your titles and abstracts with this in mind!)
• SciFinder Scholar automatically helps us in many ways, but we still need to “apply Scientific Method in information retrieval”.
Database
Content
Not to be distributed without permission
Substance Database Record
There are many issues relating to the indexing of substances, and we shall learn some of them soon
The Chemical Abstracts
Service substance database
Database
Content
Not to be distributed without permission
Reaction Database Record
There are many issues relating to building reaction databases, and we shall learn some of them soon
The Chemical Abstracts
Service reaction database
Database
Content
Not to be distributed without permission
Topic Search
• The topic we are going to discuss may not interest you - but please consider the process and then try to think how to use the functionality to facilitate your research
• We shall see how to work through the problem - using Scientific Method!
Topic
Search
• The topic:– how to analyze for benzaldehydes in sake
Not to be distributed without permission
Initial Search: Selection of Candidates
Topic
Search
• Use prepositions
• Identifies concepts
• Finds synonyms
• Attempts truncation
Not to be distributed without permission
Post-Processing
• Analyze/Refine – tools to narrow answers– Take them in steps so that we understand what we are retrieving and what we
are omitting
Topic
Search
• Get Related – tools to “expand” answers– Get additional information: citations, substances, reactions, Internet
Not to be distributed without permission
To narrow answers ….Analyze/Refine
• Many options
• Take them in steps so that we understand what we are retrieving and what we are omittingT
opic
Search
Not to be distributed without permission
Analyze References: CA Section Title
• 80 Section Titles
• Very useful for initial
filtering of answers
Topic
Search
Not to be distributed without permission
Analyze References: Index Term
• >30,000 Index Terms for Topics
• >125,000 Index Terms for organisms etc
• Systematic entries
• Very useful!Topic
Search
Not to be distributed without permission
Where are we?
• We did a search: “analysis of (benzaldehydes in) sake”
• We found the algorithm retrieved hits (>1500) with:– Sakhalin
– sakuraii ...
• We restricted answers (Analyze References):– to CAPLUS
– to Sections of Chemical Abstracts (broad refinement)
– to Index Terms (more precise refinement)
– 494 answers
• But….
How do we find the ‘benzaldehydes’? And how do we analyze for them in sake?
Topic
Search
Not to be distributed without permission
The Benzaldehydes indexed in the 494 References
Now we have to find references to the analysis of these substances in sake
Topic
Search
Not to be distributed without permission
Get Related: Substances
• Function = > structure
• The ability to find substances with specific properties/ functions is a key area:– What proteins/sequences have <the properties> I need?
– What monomers/polymers are useful for miniemulsions?
– What natural products have been isolated from these organisms?
– What phthalocyanines/porphyrins have been used in photodynamic therapy?
– What polymers have been used for automobile brakes?
– What antidiabetic agents are known?
– What drug formulations have been used in gene therapy?
– What co-ordination compounds has Dave Garner reported recently?
Topic
Search
Not to be distributed without permission
Summary
• SciFinder Scholar applies intelligence at the initial search level– relevance ranked list of candidates - choices!
– automatic application of synonyms
• SciFinder Scholar provides post-processing tools– Narrowing answers
• Analyze/Refine References - indexing!
– Additional information (broadening answers)
• Get Related
– citations
– substances
– reactions
Topic
Search