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NOVUS BIOLOGICALS ANTIBODIES FOR
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Table of ContentsG-Protein Coupled Receptors .. 2-6Signal Transduction .............. 7-8Epigenetic Regulation .........9-10
Neurogenesis and Gliogenesis ....................11-12
Axon Function and Structure ...13
Sensory Systems: Auditory & Olfactory ..............14Sensory Systems: Vision ...15-16 CNS Control of Metabolism ....17Alzheimer’s Disease ...............18Parkinson’s Disease .........19-20Huntington’s Disease .............21
Multiple Sclerosis ...................22
Stroke, Epilepsy & Traumatic Brain Injury ............................22
Neuronal Markers ...........23-24
Antibody Support Products ......25
Technical Support ...................26
Application KeyChIP - Chromatin Immunoprecipitation
DB - Dot Blot
ELISA - Enzyme-linked Immunosorbent Assay
FACS - Fluorescent Activated Cell Sorting
ICC - Immunocytochemistry
IF - Immunofluorescence
IHC - Immunohistochemistry
IHC-Fr - Immunohistochemistry Frozen
IHC-P - Immunohistochemistry Paraffin
IP - Immunoprecipitation
PEP-ELISA - Peptide Enzyme-linked Immunosorbent Assay
RIA - Radioimmunoassay
WB - Western Blot
Reactivity KeyAv - Avian
Am - Amphibian
Bv - Bovine
Ca - Canine
Ce - C. elegans
Ch - Chicken
Dr - Drosophila
Fe - Feline
Fi - Fish
GP - Guinea Pig
Hu - Human
Le - Leech
Ma - Mammal
Mk - Monkey
Mu - Mouse
Po - Porcine
Rb - Rabbit
Rt - Rat
Xp - Xenopus
Ze - Zebrafish
1
Making Your Success Our GoalNovus is committed to providing researchers with the highest quality antibodies so they may focus on their research. That’s why we’re continually working to provide the most comprehensive data available for our products.
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G-protein coupled receptors (GPCRs) have been implicated as signal transducers in a wide variety of physiological processes including sensory systems where they bind opsins, odorants and tastants. GPCRs also affect behavior and mood regulation through interaction with an array of neurotransmitters, including serotonin and dopamine.
G-Protein Coupled Receptors
Purinergic ReceptorsPurinergic receptors bind derivatives of the nucleotide adenosine. Purinergic receptors have been implicated in a wide array of biological processes including modulation of peripheral auditory and visual sensory systems.
Related Antibodies
• Adenosine A1 Receptor
• Adenosine A2a Receptor
• Adenosine A2b Receptor
• Adenosine A3 Receptor
• GPR17
• GPR86
• P2RY1
• P2Y2
• P2Y4
• P2Y6
• P2Y8
• P2Y10
• P2Y11
• P2Y12
GPR17 Antibody NLS4229
Immuno-histochemicalanalysis of humanbrain (neuronsand glia) usingNLS4229.
Species: HuApplications: IHC-P
Adenosine A2a Receptor (7F6-G5-A2) Antibody NBP1-39474
Immuno-histochemicalanalysis of human brainusing NBP1-39474.
Species: Hu, Mu, Rt, Ca, GP, RbApplications: WB, FACS, IHC-P
Adregergic ReceptorsThe adrenergic receptors (adrenoceptors) are targets of catecholamines, excluding dopamine.Binding of an agonist to one of these receptors generally triggers a sympathetic (fight-or-flight) response.
Related AntibodiesAlpha 2a Adrenergic Receptor Antibody NBP1-67832
Immuno-histochemicalanalysis of humantestis tissueusing NBP1-67832.
Species: Hu, Mu, RtApplications: WB, ELISA, IF, IHC-P
Calcium-Sensing ReceptorCalcium-sensing receptors (CaSRs) sense extracellular levels of calcium ions. The binding of calcium induces a conformational change in the receptor and triggers the phospholipase C pathway, ultimately increasing the intracellular concentration of calcium.
Immuno-histochemicalanalysis of humanpancreas usingNBP1-84687.
Species: HuApplications: WB, IHC-P
Calcium Sensing Receptor Antibody NBP1-84687
• Alpha 1 Adrenergic Receptor
• Alpha 1b Adrenergic Receptor
• Alpha 1d Adrenergic Receptor
• Alpha 2a Adrenergic Receptor
• Alpha 2b Adrenergic Receptor
• Alpha 2c Adrenergic Receptor
• Beta 1 Adrenergic Receptor
• Beta 2 Adrenergic Receptor
• Beta 3 Adrenergic Receptor
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5-Hydroxytryptamine Receptors5-hydroxytryptamine (5-HT) receptors, also known as serotonin receptors, are found in the central and peripher-al nervous systems where they mediate neurotransmission and have been implicated in a wide array of biologi-cal and neurological processes including appetite, mood, nausea, sleep, and sexuality.
• 5HT1A
• 5HT1D
• 5HT1E
• 5HT1F
• 5HT2A
5-HTR2C Antibody NBP1-90317
Immuno-histochemicalanalysis of human pancreasusing NBP1-90317.
Species: HuApplications: WB, IF, IHC-P
5-HTR1A Antibody NBP1-90321
Immuno-histochemicalanalysis ofthymus, endothelialrecticular cellsusing NBP1-90321.
Species: HuApplications: IHC-P
Neuropeptide ReceptorsNeuropeptides function as intracellular signaling molecules and affect gene expression, local blood flow, synaptogenesis and glial cell morphology. Neuropeptides are packaged in large, dense-core vesicles and are located on every part of a neuron, including the soma, dendrites, axonal swellings and nerve endings.
Related Antibodies
• GPR8
• GPR154
• Neurotensin Receptor 1
• Neurotensin
Receptor 2
• NMBR
• NMUR1
• NMUR2
• NPFFR1
• NPFFR2
• NPBWR1
• NPYR5
• NTSR2
NMBR AntibodyNBP1-89520
Immuno-fluorescent analysis showing positivityin plasmamembrane & cytoplasmusing NBP1-89520.
Species: HuApplications: WB, IF, IHC-P
NMUR1 Antibody NBP1-83433
Immuno-histochemicalanalysis ofof human duodenumusing NBP1-83433.
Species: HuApplications: WB, IHC-P
Bombesin ReceptorsThis class of receptors is located largely in the central nervous system and the gastrointestinal tract. Bombesin receptors mediate the nuerological anxiety response as well as smooth muscle contraction and eating behavior. These ligands have also been implicated in many neurodegenerative diseases.
Immuno-histochemicalanalysis of placentausing NLS4915.
Species: HuApplications: IHC-P
Bombesin Receptor 3 Antibody NB100-74372
Immuno-histochemicalanalysis ofhuman pancreaticcarcinoma tissuesections usingNB100-74372.
Species: HuApplications: WB, IHC, IHC-P
Bombesin Receptor 3 Antibody NLS4915
Related Antibodies
• 5HT2B
• 5HT2C
• 5HT5A
• 5HT6
• 5HTR7
G-Protein Coupled Receptors
GRPR Antibody NB100-74434
Immuno-histochemicalanalysis of humanmammary carcinomatissue usingNB100-74434.
Species: HuApplications: WB, IHC-P
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Muscarinic Acetylcholine ReceptorsAcetylcholine (ACh) is an abundant neurotransmitter, found in the central nervous system, autonomic preganglia and spinal motor neurons. There are two main subtypes of ACh receptors – nicotinic and muscarinic. Muscarinic receptors (mAChRs) are responsible for the post stimulation hyperpolarization and slow depolarization of the postganglionic neuron. mAChRs modulate an array of physiological functions, including smooth muscle contractions, heart rate, and glandular secretions
Muscarinic Acetylcholine Receptor 2 Antibody NBP1-86351
Immuno-histochemicalanalysis of humankidney usingNBP1-86351.
Species: HuApplications: IHC-P
Muscarinic Acetylcholine Receptor M4 Antibody NBP1-70994
Immuno-fluorescent analysis of LOVO cells usingNBP1-70994.
Species: Hu, Mu, RtApplications: ELISA, IF
Dopamine ReceptorsMany neurological responses are modulated by dopamine signaling. There are two families of dopamine receptors: the D1-like family (D1 and D5) and the D2-like family (D2 through D4). Activation of receptors in the D1-like family activates adenylyl cyclase, increasing the intracellular concentration of cAMP. Conversely, activation of receptors in the D2-like family inhibits the formation of cAMP by inhibiting adenylate cyclase.
Species: HuApplications: IHC-P
Immuno-histochemicalanalysis of Kidney, Proximal & distal cinvoluted tubules using NLS44.
Species: HuApplications: ICC, IHC-P
Dopamine Receptor D1 Antibody NLS44
Customer Review
Dopamine Receptor D1 Antibody (SG2-D1a)(NB110-60017)Application: IHC-FrSample Tested: Rat retinal whole mounts and sectionsSpecies: RatLot: A1
Dopamine Receptor D1 Antibody NBP1-87577
Immuno-histochemicalanalysis of human skinusing NBP1-87577.
G-Protein Coupled Receptors
Tuftelin 1 Antibody Antibody NBP1-87446
Species: HuApplications: WB, IHC-P
Immuno-histochemicalanalysis of human duodenum usingNBP1-87446.
GABA-B ReceptorsGABA-B receptors are inhibitory receptors found in the central and peripheral autonomic nervous systems. Ligand binding triggers a signaling cascade that ultimately inhibits neurotransmitter release. GABA-B receptors may play important roles in the development and sensation of pain.
GABA B Receptor 1 Antibody NBP1-19356
Immuno-histochemicalanalysis of humanbrain tissue usingNBP1-19356.
Species: Hu, Mu, RtApplications: WB, IHC-P
GABA B Receptor 2 Antibody NBP1-89803
Immuno-histochemicalanalysis ofhuman duodenumusing NBP1-89803.
Species: HuApplications: IHC-P
GABA B Receptor 1 Antibody NBP1-52389
Immuno-histochemicalanalysis of humanbrain cortex usingNBP1-52389.
Species: Hu, Mu, Rt, Bv, CaApplications: IHC-P
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Cannabinoid Receptors Cannabinoids are a group of terpenophenolic compounds present in the nervous and immune systems. There are two defined types of cannabinoid receptors, designated CB1 and CB2. CB1 receptors are considered the most widely expressed GPCRs in the brain.
Cannabinoid Receptor II Antibody NBP1-88175
Immuno-histochemicalanalysis of humanhippocampususing NBP1-88175.
Species: HuApplications: WB, IHC-P
Immuno-histochemicalanalysis of brain, neuronsusing NLS31.
Species: Hu, Rt, MkApplications: ICC, IHC-Fr, IHC-P
Cannabinoid Receptor I Antibody NLS31
Histamine ReceptorsHistamine is a biogenic amine that is involved in local immune responses, digestive regulation and neurotransmission.
Histamine H4 Receptor Antibody NBP1-90058
Immuno-histochemicalanalysis of humancorpus, uterineusing NBP1-90058.
Species: HuApplications: WB, IHC-P
Histamine receptor H3 Antibody NLS476
Immuno-histochemicalanalysis showingtransfection positiveusing NLS476.
Species: HuApplications: IHC-P
Vasopressin ReceptorsVasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a peptide hormone responsible for regulating the body’s retention of water, as well as a variety of neurological effects.
AVPR1B Antibody NB100-96917
Immuno-histochemicalanalysis of humananterior pituitary glandusing NB100-96917.
Species: HuApplications: IHC, PEP-ELISA
Western blotanalysis ofNIH3T3 lysateusing NBP1-00157.
Species: Hu, MuApplications: WB, PEP-ELISA
AVPR2 Antibody NBP1-71315
Immuno-fluorescent analysis of MCF7 cells usingNBP1-71315.
Species: HuApplications: WB, ELISA, IF
AVPR1A Antibody NBP1-00157
Somatostatin ReceptorsSomatostatin is a peptide hormone that interacts with G-protein coupled somatostatin receptors. Somatostatin is an inhibitory hormone that functions in regulation of the endocrine system, neurotransmission and cell proliferation.
Somatostatin Receptor 2 Antibody NB300-157
Immuno-histochemicalanalysis of rattissue usingNB300-157.
Species: Hu, Mu, RtApplications: WB, IF, IHC-Fr, IHC-P, IP
Western blotanalysis from rat pancreas using NB300-120.
Species: Hu, Mu, RtApplications: WB, IP
Somatostatin Receptor 3 Antibody NB100-74538
Immuno-histochemicalanalysis ofhuman pancreaticislands usingNB100-74538.
Species: HuApplications: WB, ICC, IHC-P
Somatostatin Receptor 1 Antibody NB300-120
G-Protein Coupled Receptors
Histamine Antibody NBP1-78351
Immuno-histochemicalanalysis of of rat hypothalamus using NBP1-78351.
Species: Hu, Rt, Dr, Le, OtherApplications: IHC-Fr, IHC-P
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Immuno-histochemicalanalysis of humanhippocampususing NBP1-88175.
Species: HuApplications: WB, IHC-P
Latrophilin ReceptorsLatrophilin receptors are brain-specific, calcium-independent orphan GPCRs of the secretin family. Latrophilin-1 and latrophilin-2 bind alpha-latrotoxin, a potent pre-synaptic neurotoxin present in the venom of black widow spiders.
LPHN2 Antibody NBP1-71100
Immuno-histochemicalanalysis of humanbreast carcinomatissue usingNBP1-71100.
Species: Hu, Mu, RtApplications: ELISA, IF, IHC
Immuno-fluorescent analysis ofLOVO cellsusing NBP1-71099.
Species: Hu, Mu, RtApplications: ELISA, IF
LPHN3 Antibody NLS1138
Immuno-histochemicalanalysis ofbrain, neurons andglia usingNLS1138.
Species: HuApplications: IHC-P
LPHN1 Antibody NBP1-71099
Brain-Specific Angiogenesis InhibitorsBrain-specific angiogenesis inhibitors (BAIs) are orphan GPCRs with unknown ligands. There are three BAI genes, which have similar tissue specificities and structures. BAI expression has been reported primarily in the brain.
Immuno-histochemicalanalysis ofmouse brainusing NB110-81536.
Species: Hu, MuApplications: IHC-P
BAI3 Antibody NBP1-82996
Immuno-histochemicalanalysis ofhuman duodenumusing NBP1-82996.
Species: HuApplications: IHC-P
BAI1 Antibody NB110-81586
Customer Reviews
BAI1 Antibody (NBP1-00723)Application: IFSample Tested: THP1 cell line Species: Human
GHRH Receptor Growth hormone releasing hormone receptor (GHRHR), stimulates growth hormone (GH) secretion and synthesis in the pituitary gland. Mutations in GHRHR can cause either GH deficiency, resulting in dwarfism, or excessive production of GH, leading to gigantism. GHRHR is primarily expressed in the brain.
Parathyroid Hormone ReceptorsParathyroid hormone receptors (PTHRs) bind parathyroid hormone (PTH), parathyroid hormone- related peptide (PTHRP), and tuberoinfundibular peptide 39. PTHR2 has only been identified in the brain. Due to its neuronal localization, PTHR2 is thought to function as a neurotransmitter receptor.
Immuno-histochemicalanalysis in human ovarian carcinoma samples usingNB100-74424.
Species: HuApplications: WB, ICC, IHC, IHC-P
GHRHR Antibody NB100-74424
Parathyroid Hormone Receptor 1 Antibody (4D2) NBP1-51640
Immuno-fluorescent analysisof SK-BR-3 cellsusing PTH1Rmouse mAb (green)using NBP1-51640.
Species: HuApplications: WB, ELISA, IF, IHC-P
Parathyroid Hormone Receptor 2 Antibody NLS250
Immuno-histochemicalanalysis ofbrain, neuronsand glia usingNLS250.
Species: HuApplications: IHC-P
G-Protein Coupled Receptors
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ChannelsChannels are especially important in transmitting signals from sensory organs to the brain. Channels act both as receptors that transfer signals and as openings in the plasma membrane to allow chemicals such as potassium and calcium to move into and out of a cell.
Signal TransductionRelated Antibodies
• 5HT3A Receptor
• ATP5E
• CACNB4
• Cav1.2
• KCNH1
• Kv1
• Kv1.2
• Kv1.3
• NMDAR1
• Potassium voltage- gated channel
• TREK 1
• TRPA1
• TRPC3
• TRPC4
• TRPC5
• TRPM2
TRPA1 Antibody NB110-40763
Immuno-histochemicalanalysis of mouseintestine usingNB110-40763.
Species: Hu, MuApplications: WB, IHC, IHC-P
TRPM2 Antibody NB110-81601
Immuno-cytochemicalanalysis ofrat hippocampususing NB110-81601.
Species: Mu, RtApplications: WB, ICC, IF, IHC
NMDA Receptors NMDA receptors are ionotropic glutamate receptors that regulate the opening and closing of ion channels that control the flux of Ca2+, K+, and Na+ into and out of cells. NMDA receptor interactions are crucial to proper cellular function and communication, especially in neurons. Malfunctioning NMDA receptors may be a crucial factor in Huntington’s Disease.
Related Antibodies
• NMDAR2B
• NMDA Receptor C1
• NMDA Receptor N1
• NMDAR1
• NMDAR2A
• NMDAR2C
• NMDAR2D
• NMDAR3A
• NMDAR3B
• NMDARA1
NMDA receptor N1 Antibody NB300-114
Western blotanalysis of HEK 293 cells using NB300-114.
Species: Hu, Mu, RtApplications: WB, DB, IHC-Fr
NMDAR1 AntibodyNBP1-20085
Immuno-histochemicalanalysis of human spinalcord tissue usingNBP1-20085.
Species: Hu, Mu, RtApplications: IHC-P
NMDAR2B Antibody NBP2-12999
Immuno-histochemicalanalysis of human braintissue usingNBP2-12999.
Species: HuApplications: IHC-P
Customer Reviews
NMDAR1 Antibody (NB100-74473)Application: IHC-FrSample Tested: Tissue sections of mouse brainSpecies: Mouse
NMDAR1 Antibody (NB100-92192)Application: IHC-PSample Tested: RatSpecies: Rat
NMDAR2B Antibody (NB300-106)Application: IFSample Tested: Rat brain tissueSpecies: OtherOther Species: Donkey anti-rabbit
Kv1.2 AntibodyNBP1-42802
Immuno-cyctochemicalanalysis in 293 human embryonic kidney cells using NBP1-42802.
Species: Hu, Mu, Rt, Bv, Ca, Po, Xp, ZeApplications: WB, ICC
Cav1.2 AntibodyNBP1-42817
Immuno-cyctochemicalanalysis in mouse 3T3 fibroblasts using NBP1-42817.
Species: Hu, Mu, Rt, Bv, Ca, RbApplications: WB, ICC, IF, IP
KCNH1 AntibodyNBP1-42816
Western blotanalysis in HEK cells using NBP1-42816.
Species: Hu, Mu, Rt, BvApplications: WB, ICC, IF, IP
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Related Antibodies
Related Antibodies
Signaling ProteinsSignaling proteins facilitate the cellular implementation of messages received from other cells and organ systems, providing a transition between neurons and the cells that they affect.
Related Antibodies
• Calmodulin
• Calreticulin
• RGS1
• SNAP25
• Striatin
• Synaptotagmin
Calreticulin Antibody NB600-101
Western blot analysison human kidney lysate usingNB600-101.
Species: Hu, Mu, Rt, BvApplications: WB, ICC, IF, IHC
Striatin Antibody NB110-74571
Immuno-fluorescentanalysis ofNIH3T3 cells using NB110-74571.
Species: Hu, Mu, RtApplications: WB, IF, IP
[NMDAR1 (R1JHL) Antibody NB300-118] Tao P-L, Chen C-F, Huang EY-K. Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat off-spring. J Biomed Sci. 2011 Aug 23;18(1):64. [PMID: 21861871][NMDAR2B Antibody NB300-106] Tse YC, Bagot RC, Hutter JA, et al. Modulation of Synaptic Plasticity by Stress Hormone Associates with Plastic Alteration of Synaptic NMDA Receptor in the Adult Hippocampus. PLoS ONE. 2011 6(11). [PMID: 22069501][NMDAR2B Antibody NB300-106 and NMDAR2B Antibody NB300-116] Das SR, Magnusson KR. Changes in expression of splice cassettes of NMDA receptor GluN1 subunits within the frontal lobe and memory in mice during aging. Behav. Brain Res. 2011 Sep 12;222(1):122-133. [PMID: 21443909][SNAP25 Antibody NB100-1492] Guedj F, Pereira PL, Najas S, et al. DYRK1A: A master regulatory protein controlling brain growth. Neurobiology of Disease. 2012 Jan 26. [PMID: 22293606][TRPM2 Antibody NB110-81601] Bai JZ, Lipski J. Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture. Neurotoxicology. 2010 Jan 12. [PMID: 20064552] [TRPM2 Antibody NB110-81601and TRPM2 Antibody NB500-242] Chung KK, Freestone PS, Lipski JL. The expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat. J Neurophysiol. 2011 Sep 7. [PMID: 21900507]
Product Citations
SNAP25 Antibody NBP1-88769
Immuno-histochemicalanalysis of human cerebralcortex usingNBP1-88769.
Species: Hu Applications: WB, IHC-P
Calmodulin (2D1) Antibody NB120-2860
Immuno-fluorescentanalysis inrat brain usingNB120-2860.
Species: Rt, Ba, Bv, ChApplications: WB, ELISA, ICC, IF
Synaptotagmin 2 Antibody NBP1-90356
Immuno-histochemicalanalysis of human stomach using NBP1-90356.
Species: HuApplications: WB, IF, IHC-P
RGS1 AntibodyNBP1-68645
Immuno-histochemicalanalysis of human coloncarcinoma tissueusing NBP1-68645.
Species: Hu, Mu, RtApplications: ELISA, IHC-P
Calreticulin (1G6A7) Antibody NBP1-47518
Immuno-fluorescentanalysis of 3T3-L1cells using NBP1-47518.
Species: Hu, Mu Applications: WB, ELISA, IF
Synaptotagmin 1 Antibody NBP1-61218
Immuno-histochemicalanalysis of human breastcarcinoma tissueusing NBP1-61218.
Species: Hu, Mu, RtApplications: WB, ELISA, IHC
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Chromatin modification and DNA-modifying enzymes have been shown to regulate various pathways in the development and function of the nervous system. Several areas of epigentics control of neural activity actively studied include histone acetylation and DNA methylation in response to neutrotrophin signaling as well as how DNA methylation, histone modification and transcriptional feedback loops promote self-renewal and differentiation of adult neural stem cells. [PMID: 20975746]
Epigenetic Regulation
• alpha-Synuclein• Amyloid beta Precursor Protein• BACE1• BDNF• beta Amyloid• c-FOS• Gamma-secretase• GNAT• Histone H3
• Histone H3 [Monomethyl Lys9]
• Histone H3 [Trimethyl Lys9]• Histone H4• Huntingtin• MeCP2• NFkB• NRSF• p21• REST• SETDB1• SMCX
Related Antibodies
Histone H3 [Dimethyl Lys9] Antibody NB21-1072
Western blot analysis of H3K9me2 in C. elegans embryo lysate usingNB21-1072.
Species: Hu, Mu, Rt, Ce, MaApplications: WB, ChIP, DB, ICC, IF
Histone H3 [Sym-dimethyl Arg2, Dimethyl Lys4] Antibody NB21-1202
Chromatin from one million formaldehyde cross-linked Hela cells was used with 2 ug of NB21-1202.
Species: Hu, Mu, CeApplications: WB, ChIP, DB, ICC, IF
beta Amyloid (MOAB-2) Antibody NBP2-13075
Western blot analysis of betaAmyloid inHEK-APP SWE/BACE1 cellsusing NBP2-13075.
Species: Hu, MuApplications: WB, ELISA, ICC, IF, IHC-P, IP
Customer Reviews
FOS Antibody (NB100-91772)Application: IHCSample Tested: MouseSample Pretreatment: Citrate bufferSpecies: Mouse
p21 Antibody (WA-1) (NB500-303)Application: Western blotSample Tested: Horse skinSample Pretreatment: 100 ugSpecies: Equine
Histone H3 Antibody (NB500-267)Application: Western blotSample Tested: HeLa cell lysatesSample Pretreatment: 50 ugSpecies: Rat
MeCP2 Antibody (NB600-1101)Application: Western blotSample Tested: iPS (Induced Pluripotent stem cells derived from AFMSC)Sample Pretreatment: Lysis bufferSpecies: Human
Histone Acetyltransferase Antibodies
• AIB1
• CLOCK
• ELP3
• KAT1
• KAT2A
• KAT3A/CBP
• KAT3B/p300
• KAT6B-MORF
• MYST1
• MYST3
• NCOA2
• PCAF
• SRC1
• TAF1
• TIP60
KAT3B/p300 (RW128) Antibody NB100-507
Western blot analysis of p300in a HeLa nuclearexctract usingNB100-507.
Species: Hu, Mu, Rt, MkApplications: WB, IF, IP
KAT3A/CBP Antibody (NB100-381)Application: IPSample Tested: HeLa cell lysatesSpecies: Human
Customer Review
TIP60 Antibody NBP1-61537
Immuno-histochemical analysis of human liver carcinoma tissue usingNBP1-61537.
Species: Hu, MuApplications: ELISA, IF, IHC
CLOCK AntibodyNB100-126
Western blotanalysis of alpha CLOCK immunoprecipitated DNA using NB100-126.
Species: Hu, MuApplications: WB, ChIP
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Histone H3 [Dimethyl Lys9] Antibody NB21-1072
Western blot analysis of H3K9me2 in C. elegans embryo lysate usingNB21-1072.
Species: Hu, Mu, Rt, Ce, MaApplications: WB, ChIP, DB, ICC, IF
KAT3A/CBP Antibody (NB100-381)Application: IPSample Tested: HeLa cell lysatesSpecies: Human
TIP60 Antibody NBP1-61537
Immuno-histochemical analysis of human liver carcinoma tissue usingNBP1-61537.
Species: Hu, MuApplications: ELISA, IF, IHC
Histone Deacetylase Antibodies
• HDAC1
• HDAC2
• HDAC3
• HDAC4
• HDAC5
• HDAC6
• HDAC7
• HDAC8
• HDAC9
• HDAC10
• HDAC11
• Sir2.1
• SIRT1
• SIRT2
• SIRT3
• SIRT4
• SIRT5
• SIRT6
• SIRT7
SIRT6 Antibody NB100-2522
Species: MuApplications: IHC-P, WB
Immuno-histochemical analysis of human testes tissue using NB100-2522.
HDAC6 Antibody NBP1-78981
Species: HuApplications: IF, ICC
Immuno-cytochemicalanalysis in HeLa cells with FITC (green) using NBP1-78981.
SIRT1 Antibody NBP1-49540
Species: HuApplications: IHC, WB
Immuno- histochemical analysis in human renal cell carcinoma using NBP1-49540.
[alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380] Huang Z, Xu Z, Wu Y, Zhou Y. Determining nuclear localization of alpha-synuclein in mouse brains. Neuroscience. 2011 Oct 19. [PMID: 22033456][BACE1 NB120-2077] Chang W, Barnes AM, Cabral WA, et al. Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex. Hum Mol Genet. 2010 Jan 15;19(2):223-34. [PMID: 19846465]
[CLOCK Antibody NB100-126] Xu CX, Krager SL, Liao DF, et al. Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene. Toxicol Sci. 2010 May;115(1):98-108. [PMID: 20106950][Histone H3 Antibody NB500-171] Liu R, Lei JX, Luo C, et al. Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer’s disease. Neurobiology of Disease. 2012 45(3):902-912. [PMID: 22186421][Histone H3 [Asym-dimethyl Arg8] Antibody NB21-1062] Blythe SA, et al. beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220-31. [PMID: 20708585][Histone H3 [Dimethyl Lys36] Antibody NB21-1252] Hsia DA, et al. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9671-6. [PMID: 20457893][Histone H3 [p Thr3, Monomethyl Lys4] Antibody NB21-1012] Metzger E. et al, Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature. 2010 Apr 1;464(7289):792-6. [PMID:20228790][KAT3B/p300 Antibody NB500-161] Luo W, Hu H, Chang R, et al. Pyruvate Kinase M2 is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1. Cell. 2011 May 27;145(5):732-44. [PMID: 21620138][p21 (WA-1) Antibody NB500-303] Deschene K, Céleste C, Boerboom D, Theoret CL. Constitutive expression of hypoxia-inducible factor-1 a in keratinocytes during the repair of skin wounds in horses. Wound Repair Regen. 2011 Mar-Apr;19(2):250-9. [PMID: 21362093][SETDB1 Antibody NBP1-84790] Ceol CJ, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 2011 Mar 24;471(7339):513-7. [PMID: 21430779][SMCX Antibody NB100-55328] M. L. C. Powell, J. A. Smith, M. E. Sowa, et al. NCoR1 Mediates Papillomavirus E8^E2C Transcriptional Repression. J. Virol. 2010 84 (9): 4451-4460. [PMID: 20181716]
Product Citations
Novus offers our Epi-Plus™ antibodies for modified histones. All Epi-Plus™ antibodies are multi-assay validated, including testing by dot blots using modified peptide arrays, western blots, and chromatin immunoprecipitation (ChIP). Learn more at www.novusbio.com/epi-plus.html
Epi-Plus®
HDAC2 Antibody NBP1-87109
Species: HuApplications: WB, IF, IHC-P
Immuno-fluorescentanalysis showingpositivity in nucleiusing NBP1-87109.
Visit www.novusbio.com for complete product listings. www.novusbio.com • [email protected]
Neurogeneisis is the formation of new neuronal cells. Once thought only to occur in developing organisms, recent studies have shown that neurogeneis occurs through an organism’s lifespan and plays a crucial role in neuron plasticity. Gliogeneisis is the formation of non-neuronal glia population. Glia cells function to support neural cells by providing physical structure and insulation, supplying nutrients and destroying pathogens. The Notch signaling pathway plays a major regulatory role in both events which are also affected by the Wnt and SHH pathways. Disruption of these processes has been implicated in several neurodegenerative diseases including Parkinson’s and Multiple Sclerosis.
Neurogenesis and Gliogenesis
Related Antibodies
• AKT
• alpha Catenin
• Axin 1, 2
• beta Catenin
• CCL12
• CCL2
• CNTF
• CSPG4P5
• Delta 1, 3, 4
• Dishevelled
• EGF
• Eotaxin
• FGF
• GABA
• gamma-Secretase
• GFAP
• Glutamate Receptor 5
• HIP1
• IGF1
• IGF1 Receptor
• Jagged 1, 2
• JAK 1, 2, 3
• LRP2
• LRP5/6
• MASH1
• Neurogenin 1
• NMDA
• Notch1
• NRG1
• NUMB
• OLIG2
• PACAP Receptor
• Sonic Hedgehog
• SS18L1
• Stat 1–6
• TGF alpha
• VIP
• Wnt
Customer Reviews
PPAR delta Antibody (NB600-637)Application: IHC-P Sample Tested: Gerbil stomachSpecies: Gerbil
AKT1 Antibody (NB600-467)Application: Western blotSample Tested: Mouse spleen lysateSpecies: Mouse
FGFR1 Antibody (M19B2) (NB600-1287)Application: FACSSample Tested: Transfected cell lineSpecies: Rat
Delta 1, 3, 4
Jagged 1, 2
Notch 1, 2, 3, 4
NICD
γ-Secretase
HDACCoR
CSL
MAML
CSL
NICD
p300
X
CoA
Overview of the Notch Signaling Pathway
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Notch 1 Antibody NBP1-78292
Immuno-histochemicalanalysis in humankidney usingNBP1-78292.
Species: Hu, MuApplications: WB, IHC-P
www.novusbio.com • [email protected] 12
Western blot analysis in 1. HepG2, 2. MCF7, and 3. Cos7 whole cell lysates using NBP1-54467.
beta Catenin Antibody (12F7) Antibody NBP1-54467
NUMB Antibody NB500-178
Western blot analysis of isoforms 1 and 2 in A431 whole cell lysate using NB500-178.
IGF1 Receptor Antibody NBP1-77679
Immuno-cytochemicalanalysis in A431 cells with FITC (green) using NBP1-77679.
Jagged1 Antibody NB600-1161
Immuno-fluorescentanalysis ofhuman corneal epithelial cellsusing NB600-1161.
Neurogenin 1 (3F9) Antibody NBP1-47871
Immuno-histochemicalanalysisof prostate tissueusing NBP1-47871.
Species: Hu, Mu, Rt, Ch, MkApplications: WB, ICC, IF, IHC-P, IP
Species: Hu, Mu, Rt, ChApplications: WB
Species: Hu, Mu, Rt, MkApplications: WB, ICC, IF, IHC-P
Species: Hu, Mu, RtApplications: WB, ELISA, IF, IHC-P
Species: HuApplications: WB, IHC-P
[AKT2 Antibody NBP1-26594] Lin HP, Jiang SS, Chuu CP. Caffeic Acid Phenethyl Ester Causes p21 Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells. PLoS One. 2012;7(2). [PMID: 22347457][EGFR Antibody (29.1) NB120-10414] Kondratov, K.A., et al., Termination Of Tyrphostin AG1478 Application Results In Different Recovery Of EGF Receptor Tyrosine Residues 1045 And 1173 Phosphorylation In A431 Cells. Cell Biol. Int. 2010 34:81-87. [PMID: 19947936][GABA A Receptor gamma 2 Antibody NBP1-52033] You IJ, Jung YH, Kim MJ, et al. Alterations in the emo-tional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT1A, GABA(A), and NMDA receptors. Neuropharmacology. 2012 Feb;62(2):1034-43. [PMID: 22074644][GABA B Receptor 1 Antibody NB300-160] Luo C, Rajput AH, Robinson CA, Rajput A. Gamma- aminobutyric acid (GABA)-B receptor 1 in cerebellar cortex of essential tremor. J Clin Neurosci. 2012 Feb 7. [PMID: 22321358][GABARAP Antibody NB300-158] Diaz MR, Christian DT, Anderson NJ, McCool BA. Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. J. Pharmacol. Exp. Ther. 2011 Apr;337(1):162-170. [PMID: 21209156][GFAP Antibody NB300-141] O’Donnell LA, Conway S, Rose RW, et al. STAT1-Independent Control of a Neurotropic Measles Virus Challenge in Primary Neurons and Infected Mice. J Immunol. 2012 Feb 15;188(4):1915-23. [PMID: 22246627][HIP1 (1B11) Antibody NB300-204] Datta M, Bhattacharyya NP. Regulation of RE1 Protein Silencing Transcription Factor (REST) Expression by HIP1 Protein Interactor (HIPPI). J Biol Chem. 2011 Sep 30;286(39). [PMID: 21832040] [Notch1 Antibody NB300-251] Sciacca S, Pilato M, Mazzoccoli G, Pazienza V, Vinciguerra M. Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease. Heart Vessels. 2012 Feb 28. [PMID: 22370592][PKC delta (K15-K) Antibody NBP1-30125] Ku CS, Park Y, Coleman SL, Lee J. Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages. The Journal of Nutritional Biochemistry. 2011 Dec 29. [PMID: 22209005]
Product Citations
HIP1 (4B10) Antibody NB300-203
Western blot on HeLa whole cell extractsusing NB300-203.
Species: HuApplications: WB
Sonic Hedgehog Antibody NBP1-69270
Immuno-histochemicalanalysis ofchicken embryosusing NBP1-69270.
Species: Hu, Mu, Rt, Ca, Ch, Xp, ZeApplications: WB, IHC-P
Wnt1 (10C8) Antibody NBP1-51575
Immuno-fluorescentanalysis of 3T3-L1 cells usingNBP1-51575.
Species: Hu, MuApplications: WB, ELISA, FACS, IF, IHC-P
Immuno-histochemicalanalysis ofhuman braintissue usingNBP1-68600.
Dishevelled 3 Antibody NBP1-68660
Species: Hu, MuApplications: ELISA, IHC
Visit www.novusbio.com for complete product listings. www.novusbio.com • [email protected]
Axons are the part of a neuronal cell that carries signals away from the soma. For a given neuronal cell type, axons may vary greatly and undergo extensive branching. Axonal growth is stimulated by a variety of neutrophic growth factors (NTFs) and also regulated by Src family kinases (SFKs). [PMID: 17646673] Guidepost cells assist in axon growth and play a role in neuroregeneration, in which damaged axons regenerate synaptic connections with other neurons. Under normal physiological conditions, “axon-pruning” occurs as a mechanism to maintain connectivity and plasticity and also to repair damaged axons. [PMID: 16022592] Axon loss contributes to neurological symptoms in disorders including multiple sclerosis, stroke and chronic neurode-generative diseases. [PMID: 12220882]
Axon Function and Structure
Related Antibodies
• alpha 2 Mannosidase 2A
• BDNF
• BLK
• ChABC
• F-actin
• FGR
• FRK
• Fyn
• GDNF
• GFAP
• Gigaxonin
• GNB5
• Hck
• Laminin
• Lck
• Lyn
• Mitofusin 1, 2
• Myelin Protein Zero
• Netrin 1
• Netrin-G1 Ligand
• Neurotrophin 3
• Neurotrophin 4
• Neurturin
• NGF
• p75NTR
• PMP22
• Src
• TDP1
• TNF alpha
• TrkA
• TrkB
• TrkC
• Yes1
Immuno-cytochemical analysis in Hela cells (green)using NB300-144.
Laminin Antibody NB300-144
PMP22 (Hu1) Antibody NB110-59086
Immuno-histochemicalanalysis in dorsal root ganglion and spinal roots in 20 week fetal spinal cord usingNB110-59086.
Western blot analysis ofChondroitinaseABC usingNBP1-96141.
ChABC (6A12) Antibody NBP1-96141
Src [p Tyr418] Antibody NBP1-60970
Immuno-histochemicalanalysis human colonusing NBP1-60970.
Species: Hu, Mu, RtApplications: WB, ICC, IHC-Fr, IHC-P
Mitofusin-1 Antibody NBP1-51841
Immuno-histochemicalanalysis ofmouse intestineusing NBP1-51841.
Species: Hu, MuApplications: ICC, IF, IHC-P
Species: Hu, MkApplications: IHC-P
Species: NAApplications: WB, ELISA
Species: Hu, Mu, RtApplications: WB, WB, ELISA, IHC-P
GFAP Antibody NB300-141
Immuno-fluorescentanalysis of mixedneuron glial culturesusing NB300-141.
Species: Hu, Mu, Rt, Bv, Fe, PoApplications: WB, ICC, IF, IHC-Fr, IHC-P
Dendrite
Cell body
Myelin sheath(Schwann cell)
Node of Ranvier
Axon
Axon terminals
Customer Reviews
BLK Antibody (7A12) (H00000640-M02)Application: Western blotSample Tested: Recombinant (r) BLK, Ramos whole cell lysate, Jurkat whole cell lysateSpecies: Human
Laminin Antibody (NB300-144)Application: IHC-FrSample Tested: RatSample Pretreatment: DoxorubicinSpecies: Rat
Src [p Tyr418] Antibody (NB100-92633)Application: IFSample Tested: RatSpecies: Rat
www.novusbio.com • [email protected] 14
Species: Hu, Mu, RtApplications: WB, ICC, IHC-Fr, IHC-P
Species: Hu, Mu, RtApplications: WB, WB, ELISA, IHC-P
AuditoryHearing is a complex interaction between many structures of the ear that amplify sound vibrations, convert vibrations into electrical signals, and then carry those signals to the brain. Neurotransmitters convey signals from the hair cells of the inner ear to auditory neurons. The encoded message travels through multiple areas of the brain until it is relayed to the primary auditory cortex via the temporal lobe. Defects in certain hearing related proteins have been associated with hearing loss; these proteins include Tubby, Myosin 1C and proteins associated with Waardenburg syndrome (PAX3, MITF, EDNRB, EDN3 and SOX10.)
Related Antibodies
• ARC
• Connexin 26
• Endothelin
• Endothelin 3
• MiTF
• Myosin 1C
• PAX3
• Tubby
• TULP1
• TULP2
• TULP3
• TULP4
Tubby Antibody NB100-1922
Western blotanalysis of tub-1 (GFP complex) using NB100-1922.
Myosin 1C Antibody NBP1-87745
Immuno-histochemicalanalysis ofhuman gallbladder usingNBP1-87745.
Species: CeApplications: WB, IHC-P, IP
Species: HuApplications: WB, IHC-P
OlfactoryThe initial olfactory signal is initiated when an odorant molecule binds to an olfactory receptor which triggers the activation of a G-protein signal cascade. Olfactory receptors are GPCRs similar to those known to be important in neurotransmission and photoreception; there are as many as 1,000 genes for ORs in the mammalian genome. [PMID: 17903277]
Related Antibodies
• Adenylyl Cyclase 3
• Cyclic AMP
• F-Actin
• GABA A Receptor alpha 1
• MAP2
• NKCC1
• Phospholipase C beta 2
• TRPC6 Novus offers hundreds of antibodies for ORs. Visit www.novusbio.com and search on your gene of interest to find related products.
MAP2 Antibody NB300-213
Immuno-cytochemicalanalysis ofmixed neuron/glialcultures using NB300-213.
Adenylate Cyclase 3 Antibody NBP1-92683
Immuno-fluorecentanalysis ofMixed neuron-glial cultures usingNBP1-92683.
Species: Hu, Mu, Rt, BvApplications: WB, IF, IHC-Fr
Species: Hu, RtApplications: WB, IF
[Endothelin A Receptor Antibody NB600-836] Marroquin Belaunzaran O, Cordero MI, Setola V, Bianchi S, Galli C, Bouche N, Mlynarik V, Gruetter R, Sandi C, Bensadoun JC, Molinari M, Aebischer P. Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool. PLoS One. 2011 Apr 20;6(4):e18268. [PMID: 21533130][MAP2 Antibody NB300-213] Schätzle P, Wuttke R, Ziegler U, Sonderegger P. Automated quantification of synapses by fluorescence microscopy. Journal of Neuroscience Methods. 2011 Nov 11204(1):144-149. [PMID: 22108140]
[MAP2 Antibody NB300-213] Sur S, Pashuck ET, Guler MO, et al. A hybrid nanofiber matrix to control the survival and maturation of brain neurons. Biomaterials. 2011 Oct 19. [PMID: 22018390]
Product Citations
Sensory Systems: Auditory & Olfactory
Visit www.novusbio.com for complete product listings. www.novusbio.com • [email protected]
VisionVision is a complex process involving interactions between the surface and lens of the eye, the retina and neural receptors and the processing by the brain of information collected from the eyes. Because there are many processes involved in eyesight, a wide range of genes are involved in the processes of collecting, relaying, and processing visual signals. Likewise, mutations to any of these genes can cause problems in a variety of areas including ocular development, retinal development or degeneration, or signal transmission to the brain.
Sensory Systems: Vision
Related Antibodies
• 3-OHKYN
• Adenosine A1 Receptor
• Adenylate Cyclase 6
• ALDH1A3
• APXL
• Arrestin 3 Retinal
• BBS10
• Bestrophin
• betaTrCP
• BMAL1
• CACNA2D4
• Calnexin
• CaMK1
• Cannabinoid Receptor II
• CD147
• CEP290
• Ceramide Kinase Like
• CHX10
• clarin 1
• CLOCK
• CNNM4
• Crystallin AB
• Cytokeratin 3/12
• Dock5
• EFEMP1
• ELAVL2
• EYA3
• EYA4
• FOXE3
• GDF6
• Glutamate Receptor 1
• Glutamate receptor 2
• Glutamate receptor 2/3
• Glutamine Synthetase
• Homeobox protein SIX6
• IMPG2
• LRP5/6
• Melanopsin
• MERTK
• Metabotropic Glutamate Receptor
• mGluR1
• mGluR6/7
• Mucolipin 1
• Ndufs1
• NIR2
• OPA1
• Opsin 1 (Medium Wave)
• Opsin 3
• Otx2
• OTX3
• PAX6
• PDE6A
• PER1
• Peropsin
• PROX1
• PRPF3
• PRPF8
• Retinoic Acid Receptor alpha
• Retinoic Acid Receptor beta
• RGR
• Rhodopsin
• RIT1
• RPE65
• S Opsin
• S-arrestin
• SHH
• SNAP25
• SOX2
• Syntrophin
• Syntrophin alpha 1
• Transducin alpha
• Transducin beta
• TULP1
• WDR36
• WFS1
Customer Reviews
Mucolipin 1 Antibody (NB110-82375)Application: Western blotSample Tested: HEK lysate overexpressing mcoln1
OPA1 Antibody (NB110-55290)Application: Western blotSample Tested: COS-1 cell
SOX2 Antibody (NB110-37235)Application: Western blotSample Tested: Oral cancer cell lineSpecies: Human
www.novusbio.com • [email protected]
Western blotanalysis in A549 cell lysate using NB100-2911.
Ceramide Kinase Antibody NB100-2911
Cytokeratin 19 Antibody NBP1-78278
Immuno-histochemicalanalysis human kidney carcinoma using NBP1-78278.
Metabotropic Glutamate Receptor 6 Antibody NB300-189
Immuno-fluorecentanalysis in trapezoid body in mouse brain using NB300-189.
Species: HuApplications: WB
Species: Hu, Mu, Rt, MkApplications: WB, ICC, IF, IHC-P
Species: Mu, RtApplications: WB, IF
Western blotanalysis in in mouse brainlysates usingNB110-82375.
Mucolipin 1 Antibody NB110-82375
OPA1 Antibody NB110-55290
Immuno-histochemicalanalysis inprostatic smoothmuscle usingNB110-55290.
RPE65 (401.8B11.3D9) Antibody NB100-355
Immuno-histochemicalanalysis in mouse retina tissue using NB100-355.
Species: Hu, Mu, RtApplications: WB
Species: Hu, Mu, Rt, Ch, Mk, ZeApplications: WB, IHC
Species: Hu, Mu, Bv, PoApplications: WB, ICC, IF, IHC, IHC-Fr
[Adenylate Cyclase 3 Antibody NBP1-92683] Louvi A and Grove EA. Cilia in the CNS: the quiet organelle claims center stage. Neuron 2011 69:1046-1060. [PMID: 21435552][Crystallin AB (1B6.1-3G4) Antibody NBP1-97494] Schwirtlich M, Kwakowsky A, Emri Z, et al. GABAergic signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation. Cell Calcium. 2011 Aug 3. [PMID: 21820173][Calnexin (1D4) Antibody H00000821-M08] Teoh KT, Siu YL, Chan WL et al. The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. Mol Biol Cell. 2010 Nov;21(22):3838-52. [PMID: 20861307] [Cannabinoid Receptor II Antibody NB300-606] Patsenker E, Stoll M, Millonig G, et al. Cannabinoid Receptor Type I Modulates Alcohol-Induced Liver Fibrosis. Mol Med. 2011 Aug 19. [PMID: 21863215][CEP290 Antibody NB100-86991] Hopp K, Heyer CM, Hommerding CJ, et al. B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. Hum Mol Genet. 2011 Apr 14. [PMID: 21493627][ELAVL2 Antibody NB110-10865 ] Hayakawa H, Fujikane A, Ito R, et al. Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochem Biophys Res Commun. 2010 Nov 10. [PMID: 21073862]
[OPA1 Antibody NB110-55290] Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, et al. Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer’s Disease. PLoS ONE. 2012 7(2). [PMID: 22393443][Rhodopsin (4D2) Antibody NBP1-48334] Matsuyama T, Yamashita T, Imai H, Shichida Y. Covalent bond between ligand and receptor required for efficient activation in rhodopsin. J Biol Chem. 2010 Mar 12;285(11):8114-21. [PMID: 20042594]
Product Citations
Western blotanalysis in modified BSAusing NB100-597.
3-OHKYN (P3UI) Antibody NB100-597
Crystallin AB Antibody NB100-2520
Western blotof Lane 1: human skeletal muscle and Lane 2: mouse skeletal muscle proteins using NB100-2520.
Calnexin Antibody NB100-1974
Immuno-histochemicalanalysis inmouse bladderusing NB100-1974.
Species: Hu, AllApplications: WB, ICC
Species: Hu, MuApplications: WB
Species: Hu, MuApplications: WB, ICC, IF, IHC-P, IP
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Visit www.novusbio.com for complete product listings. www.novusbio.com • [email protected]
CNS Control of MetabolismCircadian RhythmsSleep cycles are regulated through both circadian and homeostatic processes. The biological clock genes are well conserved across species. Circadian rhythms are thought to be controlled by the interactions of a relatively small set of proteins. Gene variations and genetic defects in these proteins can lead to sleep disorders and poor adaptations to the light-dark cycle. [PMID: 17299246]
Related Antibodies
• BMAL1
• Casein Kinase 1 delta
• CLOCK
• Cryptochrome I
• CRY2
• PER2
• PER3
• Timeless
CRY2 Antibody NBP1-86273
Immuno-fluorscentanalysis showingpositivity in nuclues& cytoplasm usingNBP1-86273.
Timeless Antibody NB100-40853
Immuno-histochemicalanalysis ofbreast carcinomausing NBP1-31401.
Species: HuApplications: WB, IF, IHC-P
Species: Hu, MuApplications: WB, IF, IHC-P, IP
Food IntakeFood intake is controlled by a highly complex process. Compounds that affect food intake and that are critical for normal energy homeostasis are termed adiposity signaling molecules. Several neuropeptide and neurotransmitters have been identified as molecules that act through intermediaries as adiposity signals including Leptin, Insulin, Neuropeptide Y, Melanocortins, Noradrenaline, Dopamine, Serotonin. [PMID: 10766253]
Related Antibodies
• AGRP
• Alpha-MSH
• CARTPT
• Corticotropin Releasing Factor
• CRHBP
• Galanin
• GALP
• GalR1, 2, 3
• GLP1R
• IL1 beta
• Insulin
• Insulin Receptor
• Insulin Receptor beta
• IR-related receptor
• Leptin
• Leptin Receptor
• MCHR
• MCHR1
• MCHR2
• MRAP2
• Neuropeptide Y
• Neurotensin
• Neurotensin Receptors 1, 2
• Noradrenaline transporter
• NPY1R
• NPY2R
• NPY4R
• NPY5R
• Orexin
• Orexin A
• Orexin Receptors 1, 1/2, 2
• Oxytocin
• Oxytocin Receptor
• Serotonin
• Thyrotropin Releasing Hormone
• Urocortin
Immuno-histochemicalanalysis inmouse pancreasusing NBP1-97308.
GLP1R Antibody NBP1-97308
Neuropeptide Y Antibody NBP1-78352
Immuno-histochemicalanalysis inthe rat centralnervous systemusing NBP1-78352.
Species: Hu, MuApplications: WB, ICC, IF, IHC-P
Species: Hu, Mu, Rt, Am, Av, Fe, Fi, GP, Other, ZeApplications: ICC, IHC-Fr, IHC-P
Immuno-histochemicalanalysis inhuman breastcarcinoma tissueusing NBP1-51404.
Insulin Receptor [p Tyr1361] Antibody NBP1-51404
Species: Hu, Mu, RtApplications: WB, IHC-P
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www.novusbio.com • [email protected]
Alzheimer’s DiseaseAlzheimer’s Disease (AD) is a progressive neurodegenerative condition that affects mental capacity, especially memory and behavior. AD is characterized by two key abnormalities: amyloid plaques and neurofibrillary tangles. Apolipoprotein E (ApoE) is a lipid transport protein that plays a central role in the pathogenesis of neurodegeneration in Alzheimer’s disease. [PMID: 14657206] There is also evidence linking Reelin with neurodegeneration through binding of ApoE receptors and as a mediator of Tau hyperphosphorylation. [PMID: 15583703]
Related Antibodies
• 160kDa Neurofilament Medium
• Amyloid beta precursor protein
• ApoE
• ApoE4
• ApoER2
• Presenilin 1
• Presenilin 2
• Reelin
• Tau
ApoER2 Antibody NB100-2216
Western blotanalysis on mouse brain membrane using NB100-2216.
ApoE4 (4E4) Antibody NBP1-49529
Western blotanalysis in concentrated supernatants of CHO cells usingNBP1-49529.
Species: Hu, Mu, ChApplications: WB
Species: HuApplications: WB, ELISA, IP
Immuno-fluorescentanalysis of adultneural cells usingNB300-134.
160kDa Neurofilament Medium (3H11) Antibody NB300-134
Species: Hu, Mu, Av, MaApplications: WB, IF, IHC-P
GAPDH (2D4A7) Antibody NB300-328
Immuno-cytochemicalanalysis inHeLa cells usingNB300-328.
Species: Hu, MuApplications: WB, ELISA, ICC, IF, IHC-P
Customer Reviews
GAPDH Antibody (1D4) NB300-221Application: Western blotSample Tested: Human Hepatoblastoma Species: Human Additional Comments: The cultured cells were harvested, washed and lysed. Extracts were stored at -20C prior to analysis
GAPDH Antibody (2D4A7) NB300-328Application: Western blotSample Tested: HaCaT whole cell lysate Sample Pretreatment: UV exposure Species: Human
GAPDH Antibody (NB300-322)Application: Western blotSample Tested: PC3 Whole Cell Lysate (Human prostate cancer cell) Species: Human
[160kDa Neurofilament Medium Antibody NB300-133] Ziv-Polat O, Skaat H, Shahar A, Margel S. Novel magnetic fibrin hydrogel scaffolds containing thrombin and growth factors conjugated iron oxide nanoparticles for tissue engineering. Int J Nanomedicine. 2012;7:1259-74. [PMID: 22419873][ApoE Antibody NB100-2040] Terwel D, Steffensen KR, Verghese PB, et al. Critical Role of Astroglial Apolipoprotein E and Liver X Receptor alpha Expression for Microglial Abeta Phagocytosis. J Neurosci. 2011 May 11;31(19):7049-59. [PMID: 21562267][ApoE (WUE-4) Antibody NB110-60531] Lee CY, Tse W, Smith JD, Landreth GE. Apolipoprotein E Promotes ß-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels. J Biol Chem. 2012 Jan 13;287(3):2032-44. Epub 2011 Nov 30. PubMed [PMID: 22130662].[GAPDH (1D4) Antibody NB300-221] Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H, Whelan AM, Zukin RS, Klann E, Tassone F. Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome. Genes Brain Behav. 2012 Jan 23. [PMID: 22268788][GAPDH Antibody NB300-327] Wang M-E, Chen Y-C, Chen I-S, et al. Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes. The Journal of Nutritional Biochemistry. 2012 Jan 3. [PMID: 22221674]
Product Citations
18
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Parkinson’s disease is a motor system disorder that results from a loss of dopamine-producing neurons. Protein aggregates called Lewy bodies develop inside neural cells and displace other cellular contents. Symptoms of the disorder include trembling of the extremities and face, stiffness of movement and impaired balance and coordination. Several genes have been implicated in Parkinson’s disease. These include PARK2, PARK7, PINK1, LRRK2, SNCA, GBA, SNCAIP, and UCHL1. Mutations these genes have been linked to increased incidence of the disorder.
Parkinson’s Disease
Related Antibodies
• alpha-Synuclein
• CASK
• Caspase 1
• Caspase 8
• CD73
• Cullin 1
• Cyclin E
• DARPP32
• DORFIN
• Drebrin
• GBA
• Glutamate Dehydrogenase
• GNB3
• Hsp70
• LRRK2
• Park7(DJ-1)
• Parkin
• PINK1
• Proteasome 26S S5
• Rhodopsin
• Septin-5
• SIAH1
• SIAH1/2
• SIAH2
• Synphilin-1
• Tubulin alpha
• Tubulin beta
• Ube2G2
• Ube2L3
• Ube2L6
• UCHL1
Western blotanalysis ofHEK293 cell extract using NB500-208
Caspase 8 (FLICE 4-1-20) Antibody NB500-208
Species: HuApplications: WB
Hsp70 Antibody NBP1-77455
Immuno-histochemicalanalysis in humanxenograft kidney cancer usingNBP1-77455.
Species: HuApplications: ICC, IF, IHC-P
LRRK2 Antibody NB300-268
Immuno-histochemicalanalysis ofbrain using NB300-268.
Park7(DJ-1) Antibody NB300-270
Immuno-cytochemicalanalysis inhuman cortexusing NB300-270.
Species: Hu, Mu, BvApplications: WB, ICC, IF, IHC-P, IP
Species: Hu, Mu, Rt, Bv, Ch, SyHa, ZeApplications: WB, ICC, IF, In vitro, IP
UCHL1 Antibody NB300-675
Immuno-histochemicalanalysis ofneurons and theircell processes using NB300-675.
Species: Hu, Mu, Rt, Bv, Eq, GP, Mk, PoApplications: WB, IHC-P
alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380
Western blot analysis of (A) Nitrated alpha-Synuclein protein and (B) non-nitrated alpha-Synuclein protein using NBP1-26380.
SIAH2 (24E6H3) Antibody NB110-88113
Immuno-fluorescentanalysis in ovarian carcinoma (OVCR3) cells using NB110-88113.
Species: HuApplications: WB, IHC-P
Species: Hu, Dr, PoApplications: FACS, ICC, IF, IHC-Fr, IHC-P
Tubulin (YL1/2) Antibody NB600-506
Immuno-histochemicalanalysis on human breast cancer using NB600-506.
Species: Hu, Mu, Rt, Av, Ma, YeApplications: WB, ELISA, ICC, IF, IHC-Fr, IHC-P, IP, RIA
19
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alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380
Customer Reviews
alpha Tubulin (DM1A) Antibody (100-690)Application: Western blot Sample Tested: Mouse lung tissueSample Pretreatment: 95 C boilingSpecies: Mouse
GBA Antibody (H00002629-B01P)Application: IPSample Tested: Cell lysate Species: Human
Hsp70 Antibody (13D3) (NB120-2788)Application: Western blotSample Tested: HEK293 cell lysate Sample Pretreatment: 20 ug
Park7(DJ-1) Antibody (NB300-270)Application: Western blotSample Tested: HeLa whole cell lysate, mouse brain Species: Human Other Species: MousePub Med ID: 21645620
PINK1 Antibody (BC100-494)Application: Western blotSample Tested: HeLa whole cell, mito extract Sample Pretreatment: 20 ug Sample Pretreatment: CCCPSpecies: Human
alpha Tubulin (DM1A) Antibody (100-690)Application: Western blotSample Tested: Cell lysateSpecies: Mouse
Beta Tubulin Antibody (NB600-936)Application: IHCSample Tested: Hippocampal Primary Culture Species: Mouse
Beta Tubulin Antibody (NB600-936)Application: Western blotSample Tested: Chicken cell line Species: Chicken
UCHL1 Antibody (NB100-65827)Application: Immunohistochemistry-Paraffin Sample Tested: Brain tissue Species: Human
[alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380] Huang Z, Xu Z, Wu Y, Zhou Y. Determining nuclear localization of alpha-synuclein in mouse brains. Neuroscience. 2011 Oct 19. [PMID: 22033456][alpha Tubulin (DM1A) Antibody NB100-690] Kadiu I, Gendelman HE. Human Immunodeficiency Virus type 1 Endocytic Trafficking Through Macrophage Bridging Conduits Facilitates Spread of Infection. J Neuroimmune Pharmacol. 2011 Jul 26. [PMID: 21789505][Caspase 8 Antibody NB110-56116] Harcourt JL, Caidi H, Anderson LJ, Haynes LM. Evaluation of the Calu-3 cell line as a model of in vitro respiratory syncytial virus infection. J Virol Methods. 2011 Jun;174(1-2):144-9. Epub 2011 Mar 31. [DARPP32 [p Thr34] Antibody NBP1-60812] Sarantis K, Antoniou K, Matsokis N, Angelatou F. Exposure to novel environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene expression in rat hippocampus. Neurochemistry International. 2011 Nov 7. [PMID: 22080157][Drebrin (M2F6) Antibody NB100-1951] Chen Q, Prior M, Dargusch R, et al. A novel neurotrophic drug for cognitive enhancement and Alzheimer’s disease. PLoS ONE. 2011 6(12). [PMID: 22194796][Hsp70 interacting protein HIP (2G6) Antibody NB120-2813] Barker BL, Benovic JL. G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. Biochemistry. 2011 Aug 16;50(32):6933-41. [PMID: 21728385][LRRK2 Antibody NB300-954] Sharma S, Bandopadhyay R, Lashley T, et al. LRRK2 expression in idiopathic and G2019S positive Parkinson’s disease subjects: A morphological and quantitative study. Neuropathol Appl Neurobiol. 2011 Jun 23. [PMID: 21696411][Park7 (DJ-1) Antibody NB300-270] Usami Y, Hatano T, Imai S, et al. DJ-1 associates with synaptic membranes. Neurobiol Dis. 2011 May 30. [PMID: 21645620][PINK1 Antibody BC100-494] Meissner C, Lorenz H, Weihofen A, et al. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J. Neurochem. 2011 Jun; 117(5):856-67. [PMID 21426348][PINK1 Antibody BC100-494] Qi Z, Yang W, Liu Y, Cui T, Gao H, Duan C, Lu L, Zhao C, Zhao H, Yang H. Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. Neurochem Int. 2011 Oct;59(5):572-81. [PMID: 21672589][UCHL1 (BH7) Antibody NB110-58869] Zhang M, Deng Y, Luo Y, et al. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1. Journal of Neurochemistry. 2011 Dec 30. [PMID: 22212137]
Product Citations
20
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Huntington’s disease (HD) is a neurodegenerative disorder caused by an expanding polyglutamine repeat in the huntingtin gene. HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years. The HD gene product is widely expressed in human tissues, with the highest level of expression in the brain.
Huntington’s Disease
Related Antibodies
• BDNF
• Caspase 3
• Choline Acetyltransferase
• GM-CSF
• HIP1
• HOXA13
• Huntingtin
• LAMC2
• Somatostatin
Caspase 3 (CPP32 4-1-18) Antibody NB500-210
Immuno-histochemicalanalysis ofepithelial cells of the tongue base usingNB500-210.
Species: Hu, RtApplications: WB, IHC
Huntingtin Antibody NBP1-03377
Immuno-fluorescentanalysis on 1day old mousecortical cell using NBP1-03377.
Species: Mu, RtApplications: WB, IF, IHC-Fr, IHC-P
Customer Reviews
Caspase 3 Antibody (CPP32 4-1-18) (NB500-210)Application: Western Blot Sample Tested: Human Hepatoblastoma Additional comments: The cultured cells were harvested, washed and lysed. Extracts were stored at -20C prior to analysis Species: Human
Caspase 3 Antibody (CPP32 4-1-18) (NB500-210) Application: Western blotSample Tested: Human Species: Human
Choline Acetyltransferase Antibody (NB100-1615)Application: Immunohistochemistry-Paraffin Sample Tested: Mouse brainSpecies: MouseAdditional comments: : I recommend this product for any IHC-related stains.
[Active Cleaved Caspase 3 Antibody NB600-1235] Jee D, Lee WK. Inhibitory Effect of intravitreal Injection of Bevacizumab on Nerve Growth Factor. Current Eye Research. 2011 Oct 31. [PMID: 22040304][Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Fuzio P, Ditonno P, Rutigliano M, et al. Regulation of TGF-1 expression by Androgen Deprivation Therapy of prostate cancer. Cancer Letters. 2012 28;318(2):135-144. [PMID: 22269108][Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Hsu L-C, Hsu Y-W, Liang Y-H, et al. Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568. Molecules. 2012 17(1):664-673. [PMID: 22237681][Choline Acetyltransferase Antibody NBP1-30052] Sciamanna G, Tassone A, Martella G, et al. Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia. PLoS ONE. 2011 6(9). [PMID: 21912682][Somatostatin Receptor 2 Antibody NB300-157] Li F, Ryu BY, Krueger RL, et al. Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to wild type viral glycoproteins. Journal of Virology. 2011 Oct 19. [PMID: 22013043]
Product Citations
Huntingtin Antibody NBP1-89710
Immuno-fluorescentanalysis of humancell line U-2 OSshowing positivity innucleus usingNBP1-89710.
Somatostatin Antibody NBP1-78329
Immuno-fluorescentanalysis ofrat hypothalamususing NBP1-78329.
Species: HuApplications: IF, IHC-P
Species: Hu, Mu, Rt, Am, FiApplications: IF, IHC-Fr, IHC-P
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HIP1 (1B11) Antibody NB300-204
Westernblot analysison HeLa whole cell extracts using NB300-204.
Species: Hu, MuApplications: WB, IP
www.novusbio.com • [email protected]
Immuno-fluorescentanalysis ofrat hypothalamususing NBP1-78329.
Species: Hu, Mu, Rt, Am, FiApplications: IF, IHC-Fr, IHC-P
MS is an autoimmune disease caused by damage to the fatty myelin sheaths around the axons of the brain and spinal cord. Damage is caused by inflammation and results in nerve damage and slow or absent nerve signals. Susceptibility to MS is linked to genes in the Major Histocompatibility Complex and to T cell response. Disease activation biomarkers include interleukin-6, nitric oxide, nitric oxide synthase, osteopontin, and fetuin-A.
Multiple Sclerosis
Related Antibodies
• CCL3
• CCL4
• CCR1
• CCR5
• CXCL9
• CXCL10
• CXCL11
• CXCR3
• Fetuin
• HLA
• IL-6
• NOA1
• Osteopontin
• TNF alpha
• TNF betaOsteopontin (1B20) Antibody NB110-89062
Immuno-histochemicalanalysis on human lung adenocarcinomausing NB110-89062.
Species: Hu, Rt, RbApplications: WB, ICC, IHC-P, IP
IL6 (6D9A1,6C12B1) Antibody NBP1-47355
Immuno-histochemicalanalysis oflung cancer tumorusing NBP1-47355.
Species: HuApplications: WB, ELISA
Ischemic episodes, TBI and epilepsy typically result in necrotic cell death at the injury site as well as programmed cell death that is controlled via apoptotic cascades in the injured area. Specifically, the mitochondrial-mediated apoptotic pathways as well as the PI3K/AKT pathway been implicated in cell death after brain trauma. New research aims to reduce apoptosis of cells in the penumbral region after brain injury as means of preserving greater neuronal function. [PMIDs: 12684068 & 15662830]
Stroke, Epilepsy & Traumatic Brain Injury
• MEK2
• MEKK4
• MMP9
• RAIDD
• RIP1
• TNF-R1
• TRADD
• AIF
• CARD
• DEDD
• FADD
• Fas Ligand
• JNK
• MAPK
Related Antibodies CARD12 Antibody NBP1-78979
Immuno-cytochemicalanalysis in HepG2 cells with FITC (green) usingNBP1-78979.
Species: Hu, MuApplications: ICC, IF, IHC-P
JNK1 Antibody NB100-1925
Western blotanalysis in JNK-1 overexpression lysates usingNB100-1925.
Species: CeApplications: WB, ELISA, IHC-P
CCR1 Antibody NB100-702
Immuno-histochemicalanalysis ofhuman tonsilusing NB100-702.
Species: HuApplications: WB, ELISA, IHC-P
CCR5 Antibody NB100-531
Immuno-cytochemicalanalysis in HeLacells with FITC (green) usingNB100-531.
Species: Hu, MkApplications: ELISA, FACS, Func, ICC, In vitro
MAP2K1IP1/MAPKSP1 Antibody NBP1-50631
Immuno-histochemicalanalysis inmouse lungusing NBP1-50631.
Species: Hu, MuApplications: WB, ICC, IF, IHC-P
Fas Ligand (NOK-1) Antibody NB100-77833
Flow cytometricanalysis of transfected cells stained with purified NOK-1 using NB100-77833.
Species: HuApplications: FACS, ICC, IF, IP
22
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Novus offers a complete line of neuronal marker antibodies that have been validated across multiple applica-tions and species.
Neuronal Markers
Astrocyte ABCA1
Astrocyte Actin Alpha 2 Smooth Muscle
Astrocyte GFAP
Astrocyte SLC1A3
Astrocytes Survivin
Glial Cells SOX2
Glial Cells Vimentin
Microglia CD11
Microglia Ferritin
Neural Stem Cells DACH1
Neural Stem Cells GFAP
Neural Stem Cells HES1
Neural Stem Cells ISL1
Neural Stem Cells Ki67
Neural Stem Cells Musashi-1
Neural Stem Cells Nestin
Neural Stem Cells Pax2
Neural Stem Cells Pax3
Neural Stem Cells Pax6
Neural Stem Cells PLAGL1
Neural Stem Cells PLZF
Neural Stem Cells REST
Neural Stem Cells SOX9
Neural Stem Cells Vimentin
Neurons Acetylcholinesterase
Neurons Bag 1
Neurons Bcl2
Neurons beta Tubulin
Neurons Calretinin
Neurons c-Fos
Neurons Choline Acetyltransferase
Neurons ELF
Neurons HSV1
Neurons MAP2
Neurons Nestin
Neurons Neurofilament Heavy
Neurons Neurofilament Light
Neurons Neurofilament Medium
Neurons NQO1
Neurons RBFOX3/NeuN
Neurons Synapsin
Neurons UCHL1
Oligodendrocytes CNPase
Oligodendrocytes MAP4
Oligodendrocytes MOG
Oligodendrocytes Nestin
Oligodendrocytes OLIG2
Schwann Cells Laminin
Schwann Cells Ran
ABCA1 Antibody (3A1.891.3) (NB400-164)Application: Western blotSample Tested: Brain microvessel total proteins Species: Mouse
Cell Type Antibody Cell Type Antibody
SLC1A3 Antibody (NBP1-20135)Application: Western blotSample Tested: RCC4 Whole cell lysate
Survivin Antibody (NB500-201)Application: Western blotSample Tested: Oswald 1771 Abrams D17 Cancer Cell Lines Sample Pretreatment: 7-15 ug
Survivin [p Thr34] Antibody(NB500-236)Application: Western blotSample Tested: Cancer cellsSpecies: Mouse
Ki67 Antibody (NB110-89717)Application: FACSSample Tested: Mouse bone marrow cells
Ki67 Antibody (NB500-170)Application: Western blotSample Tested: Whole cell lysate Species: Mouse
Tubulin Beta 3 Antibody (NB600-1018)Application: ICCSample Tested: Mouse Differentiated Neural Cell
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ABCA1 Antibody (NB400-105)Application: Western bBlotSample Tested: MouseSpecies: Mouse
200 kDa Neurofilament Heavy Antibody NF-01 (NB500-416)Application: IFSample Tested: nerve tissue from mouse spinal cord
Customer Reviews
c-Fos Antibody (NB100-91772)Application: IHCSample Tested: MouseSample Pretreatment: Citrate buffer
www.novusbio.com • [email protected] 24
ABCA1 Antibody NB400-105
Immuno-histochemicalanalysis in prostate epithelium using NB400-105.
Survivin Antibody NB500-201
Immuno-fluorescentanalysis of telophase in the midbodies of two daughter cells using NB500-201.
Species: Hu, Mu, Rt, HaApplications: WB, FACS, ICC, IF, IHC-P, IP
Species: Hu, Mu, Rt, Ca, FeApplications: WB, ChIP, ICC, IF, IHC-P, IP
CD11b Antibody NB110-89474
Immuno-histochemicalanalysis inin human renal cancer usingNB110-89474.
Species: Hu, Mu, RtApplications: WB, FACS, ICC, IF, IHC-P
Ki67 Antibody NB500-170
Immuno-histochemicalanalysis inhuman tonsil using NB500-170.
Species: Hu, Mu, PoApplications: ICC, IF, IHC-Fr, IHC-P
Nestin (10C2) Antibody NB300-266
Immuno-cytochemicalanalysis in PC-3 cells using NB300-266.
Species: HuApplications: WB, FACS, ICC, IF, IHC-Fr, IHC-P
beta Tubulin Antibody NB600-936
Immuno-cytochemicalanalysis ofHeLa cells usingNB600-936.
Species: Hu, Mu, Rt, Ch, Mk, Po, Xp, ZeApplications: WB, ICC, IF
68kDa Neurofilament Light (DA2) Antibody NB300-132
Immuno-fluorescentanalysis ofneurons in culture usingNB300-132.
Species: Hu, Av, MaApplications: WB, IF, IHC
ZNF643 Antibody NBP1-92639
Immuno-histochemicalanalysis ofhuman testis using NBP1-92639.
Species: HuApplications: IHC-P
[68kDa Neurofilament Light Antibody NB300-131] Yokoyama K, Tezuka T, Kotani M, et al. NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. The EMBO Journal. 2011 Sep 23. [PMID: 21946561][ABCA1 (HJ1) Antibody NB100-2068] de Souza Pinto R, Castilho G, Paim BA, et al. Inhibition of Macrophage Oxidative Stress Prevents the Reduction of ABCA-1 Transporter Induced by Advanced Glycated Albumin. Lipids. 2012 Jan 21. [PMID: 22271422][Actin Alpha 2 Smooth Muscle Antibody NB600-531] Saatchi S, Azuma J, Wanchoo N, et al. Three-dimensional microstructural changes in murine abdominal aortic aneurysms quantified using immunofluorescent array tomography. J Histochem Cytochem. 2012 Feb;60(2):97-109. [PMID: 22140132][CD11b Antibody NB110-89474] Jin H, Li YH, Xu JS, et al. Lipoxin A4 analog attenuates morphine antinociceptive tolerance, withdrawal-induced hyperalgesia, and glial reaction and cytokine expression in the spinal cord of rat. Neuroscience. April 19; 208;1-10. [PMID: 22366510][CD11c (AP-MAB0814) Antibody NBP1-06651] Dravis C, Henkemeyer M. Ephrin-B reverse signaling controls septation events at the embryonic midline through separate tyrosine phosphorylation-independent signaling avenues. Dev Biol. 2011 Jul 1;355(1):138-51. [PMID: 21539827][Ferritin Antibody NB600-920] Daba A, Koromilas AE, Pantopoulos K. Alternative ferritin mRNA translation via internal initiation. RNA. 2012 Mar;18(3):547-56. [PMID: 22271759][Ki67 Antibody NB500-170] McCaskey SJ, Rondini EA, Langohr IM, Fenton JI. Differential effects of energy balance on experimentally-induced colitis. World J Gastroenterol. 2012 Feb 21;18(7):627-36. [PMID: 22363133][SLC1A3 Antibody NB100-1869] Salvatore MF, Davis RW, Arnold JC, Chotibut T. Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19). Experimental Neurology. 2012 Jan 17. [PMID: 22285253][Survivin Antibody NB500-201] Francisco R, Pérez-Perarnau A, Cortés C, et al. Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells. Cancer Letters. 2012 May 1: 318 (1) 42-52. [PMID: 22186300][Survivin Antibody (60.11) NB500-238] Schöneberger H, Weiss A, Brill B, et al. The integration of a Stat3 specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency. Hormone Molecular Biology and Clinical Investigation. 2011 Jun 135(1):1-9.
Product Citations
200kDa Neurofilament Heavy Antibody NB300-135
Immuno-fluorescentanalysis ofrat spinal cordusing NB300-135.
Species: Hu, Mu, Rt, Ma, MkApplications: WB, ELISA, IF, IHC-Fr, IHC-P
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Antibody Support ProductsNovus offers a variety of products for use in conjunction with our Primary Antibodies. All support products are also of the highest quality and are backed by our Novus Guarantee, no hassles, no nonsense.
Secondary Antibodies, Lysates, Peptides, Proteins & RNAIs
Visit www.novusbio.com and select your primary antibody of interest to see all of the related
support products.
AbSelect Antibody Purification Kits
Commercially available antibodies often contain
substances (e.g. BSA, glycine, tris, azide) that interfere in
labeling reactions. The AbSelect Purification Kit quickly removes
these contaminants.
Lightning-Link Antibody Labeling Kits
Lightning-Link is the easiest and quickest method available for making antibody (protein) conjugates, requiring just 30
seconds hands-on time.
Epitope Tags Epitope tagging is a powerful
tool for the detection and purification of expressed
proteins, and Novus Biologicals offers a wide range of epitope tag specific antibodies for a
variety of immunologicalapplications.
Isotype Controls Identify any background signal in your FACS experiment with our extensive selection of top
quality isotype control antibodies. Now available for most species, isotypes, and
fluorescent conjugates.
ELISA Kits & Matched Antibody Pairs
Our complete ELISA kits contain all of the components & reagents for a successful ELISA. Plus, it has never been easier to find the right antibody pair for
your sandwich ELISA.
Contact us about a two week free trial.*
[email protected]*Applicable in the USA only
Realize the Many Advantages of PrecipitorTM
• IP in less than 30 minutes with no centrifugation or pipetting• Rapid, multi-step automation• 96 well plate format• Multiplex up to 16 samples• Reproducible and consistent results• No external device or PC required• Affordable Price
Precipitor™ High Throughput Immunoprecipitation and Purification SystemAutomated magnetic bead platform for high-throughput precipitation and purification of proteins.
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Technical SupportNovus Biologicals stands behind all of our products 100%. We have a global team of specialists available to help you as well as detailed protocols, illustrated assay guides and video tutorials on our website. Our Techincal Support team can be reached at [email protected] and also on our live chat feature at www.novusbio.com.
Western Blot Protocol Immunocytochemistry Protocol
Chromatin Immunopreciptation Protocol
Novus Explorer This free bioinformatics tool is designed to facilitatescientific exploration of related genes, diseases and pathways based on co-citations. For moreinformation visit www.novusbio.com/explorer.
Live Chat
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