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NPTEL Video Course - Biotechnology - Biomathematics

Subject Co-ordinator - Dr. Ranjith Padinhateeri

Co-ordinating Institute - IIT - Bombay

Sub-Titles - Available / Unavailable | MP3 Audio Lectures - Available / Unavailable

Lecture 1 - IntroductionLecture 2 - Graphs and functions - ILecture 3 - Graphs and functions - IILecture 4 - Functions and derivativesLecture 5 - Calculation of derivativesLecture 6 - Differentiation and its application in Biology - ILecture 7 - Differentiation and its application in Biology - IILecture 8 - Differentiation and its application in Biology - IIILecture 9 - Differentiation and its application in Biology - IVLecture 10 - Integration - ILecture 11 - Integration - IILecture 12 - Differential equations - ILecture 13 - Differential equations - IILecture 14 - Vectors - ILecture 15 - Vectors - IILecture 16 - Vectors - IIILecture 17 - Nernst equationLecture 18 - Diffusion - ILecture 19 - Diffusion - IILecture 20 - Diffusion - IIILecture 21 - StatisticsLecture 22 - StatisticsLecture 23 - Understanding Normal distributionLecture 24 - Fitting a function to experimental dataLecture 25 - Size of a flexible proteinLecture 26 - Uniform and Poisson distributions; Knudsonâ��s analysisLecture 27 - Fourier Series - ILecture 28 - Fourier Series - IILecture 29 - Fourier transform

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Lecture 30 - Master equationLecture 31 - EvolutionLecture 32 - Tutorial - ILecture 33 - Tutorial - IILecture 34 - Temperature, Energy and EntropyLecture 35 - Partition function, Free energyLecture 36 - Bending fluctuations of DNA and spring-like proteinsLecture 37 - Force-extension and looping of DNALecture 38 - Thermodynamics of protein organization along DNALecture 39 - Learning mathematics with the help of a computer



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NPTEL Video Course - Biotechnology - Proteomics and Genomics

Subject Co-ordinator - Prof. Sanjeeva Srivastava



Lecture 1Lecture 2Lecture 3Lecture 4Lecture 5Lecture 6Lecture 7Lecture 8Lecture 9Lecture 10Lecture 11Lecture 12Lecture 13Lecture 14Lecture 15Lecture 16Lecture 17Lecture 18Lecture 19Lecture 20Lecture 21Lecture 22Lecture 23Lecture 24Lecture 25Lecture 26Lecture 27Lecture 28Lecture 29



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Lecture 30Lecture 31Lecture 32Lecture 33Lecture 34Lecture 35Lecture 36Lecture 37Lecture 38Lecture 39Lecture 40



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NPTEL Video Course - Biotechnology - NOC:Proteins and Gel-Based Proteomics




Lecture 0 - Proteins and Gel-Based Proteomics; Course IntroductionLecture 1 - Introduction to amino acidsLecture 2 - Introduction to proteinsLecture 3 - Protein folding & misfoldingLecture 4 - Protein purification techniquesLecture 5 - Introduction to proteomicsLecture 6 - Systems biology and proteomicsLecture 7 - Sample preparation and pre-analytical factorsLecture 8 - Sample preparationLecture 9 - Sample preparationLecture 10 - One-dimensional electrophoresisLecture 11 - 2-DELecture 12 - 2-DELecture 13 - 2-DELecture 14 - 2-DELecture 15 - 2-DELecture 16 - 2D-DIGELecture 17 - 2D-DIGELecture 18 - 2D-DIGELecture 19 - Protein identification using MALDI-TOF/TOFLecture 20 - Proteomics experiment data analysis & challenges



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NPTEL Video Course - Biotechnology - NOC:Mass spectrometry based proteomics




Lecture 0 - Introductory lectureLecture 1 - Introduction to proteomicsLecture 2 - Proteomics and sample preparationLecture 3 - Bacterial protein extractionLecture 4 - In-gel digestionLecture 5 - Fundamentals of mass spectrometryLecture 6 - Chromatography technologiesLecture 7 - Liquid chromatographyLecture 8 - Mass spectrometryLecture 9 - Mass spectrometryLecture 10 - MALDI sample preparation and analysisLecture 11 - Introduction to quantitative proteomicsLecture 12 - Hybrid mass spectrometry configurationsLecture 13 - SILACLecture 14 - iTRAQLecture 15 - TMTLecture 16 - Quantitative proteomics data analysisLecture 17 - Proteomics and Systems biology ILecture 18 - Proteomics & Systems biology IILecture 19 - Proteomics applicationsLecture 20 - Advances and challenges in proteomics



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NPTEL Video Course - Biotechnology - NOC:Interactomics: Protein Arrays and Label-free Biosensors




Lecture 1 - Introduction to InteractomicsLecture 2 - An overview of label-free technologiesLecture 3 - An overview of surface plasmon resonance (SPR)Lecture 4 - An overview of surface plasmon resonance imaging (SPRi)Lecture 5 - Basics of SPRLecture 6 - Basics of SPRLecture 7 - Protein immobilization for protein-protein interaction studiesLecture 8 - Protein-protein interaction studyLecture 9 - Protein-protein interaction studyLecture 10 - Protein-small molecule interaction studyLecture 11 - Protein-small molecule interaction studyLecture 12 - SPRLecture 13 - SPRLecture 14 - An overview of ellipsometry and interferometry techniquesLecture 15 - An introduction to BioLayer Interferometry (BLI) and its applications in protein researchLecture 16 - Kinetic analysis of protein-protein interaction using BLILecture 17 - Label-free quantification of proteins using BLILecture 18 - Diffraction-based biosensors - ILecture 19 - Diffraction-based biosensors - IILecture 20 - Nanotechniques in proteomics - ILecture 21 - Nanotechniques in proteomics - IILecture 22 - High throughputplatforms of interactomicsLecture 23 - Conventional label based detection techniques for Protein microarraysLecture 24 - Novel detection techniques for Protein microarraysLecture 25 - Recombinational cloning and its application for Protein microarraysLecture 26 - An introduction to Cell-free protein synthesisLecture 27 - Cell-free synthesis based protein microarraysLecture 28 - Cell-free synthesis based protein microarraysLecture 29 - Digging deeper into NAPPA



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Lecture 30 - Digging deeper into NAPPALecture 31 - Application of cell free expression protein microarrays in biomarker discoveryLecture 32 - Application of cell free expression protein microarrays in immunological studiesLecture 33 - Basics of microarray image scanningLecture 34 - Software for Image scanning and data processingLecture 35 - Microarray Data Analysis - Part ILecture 36 - Microarray Data Analysis - Part IILecture 37 - Application of protein microarray in biomarker discovery - ILecture 38 - Application of protein microarray in biomarker discovery - IILecture 39 - Systems biology and networksLecture 40 - Challenges in proteomics



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NPTEL Video Course - Biotechnology - NOC:Introduction to Proteomics




Lecture 1 - Introduction to amino acidsLecture 2 - Introduction to proteinsLecture 3 - Protein folding and misfoldingLecture 4 - Introduction to proteomicsLecture 5 - Lab session â�� Protein-protein interaction using label-free biosensorsLecture 6 - Sample preparation and pre-analytical factorsLecture 7 - Sample preparationLecture 8 - Sample preparationLecture 9 - One-dimensional electrophoresisLecture 10 - Introduction to 2-DELecture 11 - 2-DELecture 12 - 2-DELecture 13 - 2-DE ApplicationsLecture 14 - 2-DE Applications (Continued...) and ChallengesLecture 15 - Lab session - Protein/peptide pre-fractionation using OFFGEL FRACTIONATOR and data analysisLecture 16 - 2D-DIGELecture 17 - 2D-DIGELecture 18 - 2D-DIGELecture 19 - Systems biology and proteomics - ILecture 20 - Systems biology and proteomics - IILecture 21 - Fundamentals of mass spectrometryLecture 22 - Chromatography technologiesLecture 23 - Liquid chromatographyLecture 24 - Mass spectrometryLecture 25 - Mass spectrometryLecture 26 - MALDI sample preparation and analysisLecture 27 - Hybrid mass spectrometry configurationsLecture 28 - Lab session - Demonstration of Q-TOF MS technologyLecture 29 - In-gel and in-solution digestion



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Lecture 30 - Lab session - Sample preparationLecture 31 - Introduction to quantitative proteomicsLecture 32 - SILACLecture 33 - iTRAQLecture 34 - TMTLecture 35 - Quantitative proteomics data analysisLecture 36 - Proteomics applicationsLecture 37 - Challenges in proteomicsLecture 38 - OMICS and translational researchLecture 39 - Lab session â�� Targeted proteomics using triple quadrupole mass spectrometryLecture 40 - Lab session â�� Targeted proteomics



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NPTEL Video Course - Biotechnology - NOC:Introduction to Biostatistics

Subject Co-ordinator - Prof. Shamik Sen



Lecture 1 - Introduction to the courseLecture 2 - Data representation and plottingLecture 3 - Arithmetic meanLecture 4 - Geometric meanLecture 5 - Measure of Variability, Standard deviationLecture 6 - SME, Z-Score, Box plotLecture 7 - Moments, SkewnessLecture 8 - Kurtosis, R programmingLecture 9 - R programmingLecture 10 - CorrelationLecture 11 - Correlation and Regression - Part-ILecture 12 - Correlation and Regression - Part-IILecture 13 - Interpolation and extrapolationLecture 14 - Nonlinear data fittingLecture 15 - Concept of ProbabilityLecture 16 - Counting principle, Permutations, and CombinationsLecture 17 - Conditional probabilityLecture 18 - Conditional probability and Random variablesLecture 19 - Random variables, Probability mass function, and Probability density functionLecture 20 - Expectation, Variance and Covariance - Part-ILecture 21 - Expectation, Variance and Covariance - Part-IILecture 22 - Binomial random variables and Moment generating functionLecture 23 - Probability distributionLecture 24 - Uniform distribution Part-II and Normal distribution Part-ILecture 25 - Normal distribution Part-II and Exponential distributionLecture 26 - Sampling distributions and Central limit theorem - Part-ILecture 27 - Sampling distributions and Central limit theorem - Part-IILecture 28 - Central limit theorem - Part-III and Sampling distributions of sample meanLecture 29 - Central limit theorem - Part-IV and Confidence intervals



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Lecture 30 - Confidence intervals Part- IILecture 31 - Test of Hypothesis - 1Lecture 32 - Test of Hypothesis - 2 (1 tailed and 2 tailed Test of Hypothesis, p-value)Lecture 33 - Test of Hypothesis - 3 (1 tailed and 2 tailed Test of Hypothesis, p-value)Lecture 34 - Test of Hypothesis - 4 (Type -1 and Type -2 error)Lecture 35 - T-testLecture 36 - 1 tailed and 2 tailed T-distribution, Chi-square testLecture 37 - ANOVA - 1Lecture 38 - ANOVA - 2Lecture 39 - ANOVA - 3Lecture 40 - ANOVA for linear regression, Block Design



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NPTEL Video Course - Biotechnology - NOC:Introduction to Mechanobiology

Subject Co-ordinator - Prof. Shamik Sen



Lecture 1 - Need to Study MechanobiologyLecture 2 - Cell as a Tent, Individual ComponentsLecture 3 - Cell-ECM CrosstalkLecture 4 - ECM ProteinsLecture 5 - Measuring Properties of Collagen NetworksLecture 6 - Properties of Collagen NetworksLecture 7 - RheologyLecture 8 - Rheology of Biopolymer NetworksLecture 9 - Atomic Force Microscopy (AFM)Lecture 10 - Design of Protein Constructs for AFMLecture 11 - Protein Unfolding using AFMLecture 12 - Protein Unfolding using AFMLecture 13 - Focal AdhesionsLecture 14 - Focal Adhesion OrganizationLecture 15 - Focal AdhesionsLecture 16 - CytoskeletonLecture 17 - Force-velocity Relationships of Actin NetworksLecture 18 - Mesenchymal Cell MigrationLecture 19 - Actin Dynamics during Mesenchymal MigrationLecture 20 - Actin Dynamics during Mesenchymal MigrationLecture 21 - Adhesion Independent MigrationLecture 22 - Adhesion Independent and Collective Cell MigrationLecture 23 - Collective Cell MigrationLecture 24 - Mechanobiology of Stem Cell Fate - ILecture 25 - Mechanobiology of Stem Cell Fate - IILecture 26 - Mechanobiology of Stem Cell Fate - IIILecture 27 - Mechanobiology of DiseasesLecture 28 - Mechanobiology of DiseasesLecture 29 - Mechanobiology of Diseases



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Lecture 30 - Mechanobiology of DiseasesLecture 31 - Mechanobiology of DiseasesLecture 32 - Nuclear MechanotransductionLecture 33 - Nuclear MechanotransductionLecture 34 - Nuclear MechanotransductionLecture 35 - Mechanical Forces and DNA damageLecture 36 - Techniques in MechanobiologyLecture 37 - Techniques in MechanobiologyLecture 38 - Techniques in MechanobiologyLecture 39 - Techniques in MechanobiologyLecture 40 - Techniques in Mechanobiology



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NPTEL Video Course - Biotechnology - NOC:Introductory Mathematical Methods for Biologists

Subject Co-ordinator - Dr. Ranjith Padinhateeri



Lecture 1 - IntroductionLecture 2 - Graphs and FunctionsLecture 3 - Equations as GraphsLecture 4 - GraphsLecture 5 - GraphsLecture 6 - Images as 2D/3D FunctionsLecture 7 - Functions and its DerivativesLecture 8 - Computing Derivatives of CurvesLecture 9 - Rules for Calculating DerivativesLecture 10 - Understanding DerivativesLecture 11 - Curvature and Second DerivativeLecture 12 - Plotting CurvesLecture 13 - Numerical Calculation of DerivativesLecture 14 - Function, Derivatives and Series ExpansionLecture 15 - L'Hopital's Rule and Partial DerivativesLecture 16 - IntegrationLecture 17 - IntegrationLecture 18 - IntegrationLecture 19 - IntegrationLecture 20 - IntegrationLecture 21 - Exponential Growth and DecayLecture 22 - Scalars and VectorsLecture 23 - VectorsLecture 24 - Cell SymmetryLecture 25 - Gradient, Forces and FlowsLecture 26 - Gradient, Forces and FlowsLecture 27 - Understanding DiffusionLecture 28 - Diffusion Constant and Einstein Relation 1905Lecture 29 - Diffusion Equation



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Lecture 30 - Diffusion vs. Active TransportLecture 31 - Nernst EquationLecture 32 - Fourier SeriesLecture 33 - Fourier SeriesLecture 34 - Fourier TransformLecture 35 - Introduction to StatisticsLecture 36 - Mean, Standard deviation and DistributionLecture 37 - Frequency Distribution and Probability DistributionLecture 38 - Binomial DistributionLecture 39 - Normal DistributionLecture 40 - Hypothesis Testing and Mathematical Modeling



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NPTEL Video Course - Biotechnology - NOC:Bioengineering: An Interface with Biology and Medicine




Lecture 1 - Why biology for engineers - Part ILecture 2 - Why biology for engineers - Part IILecture 3 - Life processes and CellLecture 4 - Cell and its propertiesLecture 5 - Clinicianâ��s Perspective - ILecture 6 - Nucleic Acid and Central DogmaLecture 7 - DNA ToolsLecture 8 - DNA ToolsLecture 9 - DNA Tools and Biotechnology - ILecture 10 - DNA Tools and Biotechnology - IILecture 11 - DNA Tools and Biotechnology - IIILecture 12 - DNA Tools and Biotechnology - IVLecture 13 - DNA Tools and Biotechnology - VLecture 14 - DNA Tools and Biotechnology - VILecture 15 - Clinicianâ��s Perspective - IILecture 16 - Genetics - ILecture 17 - Genetics - IILecture 18 - Genetics - IIILecture 19 - Genetics - IVLecture 20 - Clinicianâ��s Perspective - IIILecture 21 - Chromosomal basis of inheritanceLecture 22 - Linkage, chromosomal disordersLecture 23 - Classical Genetics ExperimentsLecture 24 - Bacteria and VirusesLecture 25 - Clinicianâ��s Perspective - IVLecture 26 - Cell cycle disregulation and CancerLecture 27 - Developmental BiologyLecture 28 - Principles and application of Animal CloningLecture 29 - Evolution



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Lecture 30 - Clinicianâ��s Perspective - VLecture 31 - Amino acids and proteinsLecture 32 - Proteins and ProteomicsLecture 33 - Techniques to Study Protein and Proteome - ILecture 34 - Techniques to Study Protein and Proteome - IILecture 35 - Bioinformatics - ILecture 36 - Techniques to Study Protein and Proteome - IIILecture 37 - Protein Interactions and MicroarraysLecture 38 - Protein interactions and Systems biologyLecture 39 - Bioinformatics - IILecture 40 - Ethics in Research and Publications



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NPTEL Video Course - Biotechnology - NOC:Applications of Interactomics using Genomics and Proteomics Technologies




Lecture 1 - Introduction to Interactomics and Protein ArraysLecture 2 - NAPPA Technology and Protein Arrays - ILecture 3 - NAPPA Technology and Protein Arrays - IILecture 4 - BiomarkersLecture 5 - BiomarkersLecture 6 - BiomarkersLecture 7 - NAPPA and its applications in study of antibody immune response in disease and in drug Screening - ILecture 8 - NAPPA and its applications in study of antibody immune response in disease and in drug screening - IILecture 9 - NAPPA and its applications in study of antibody immune response in disease and in drug screening - IIILecture 10 - Using functional proteomics to identify biomarkers and therapeutic targets - ILecture 11 - Using functional proteomics to identify biomarkers and therapeutic targets - IILecture 12 - Applications of protein microarrays in Malaria Research - ILecture 13 - Applications of protein microarrays in Malaria Research - IILecture 14 - Applications of protein microarrays in Cancer Research - ILecture 15 - Applications of protein microarrays in Cancer Research - IILecture 16 - Introduction to Bioprinting and IrisÃ¢ Optical QC Benefits - ILecture 17 - Introduction to Bioprinting and IrisÃ¢ Optical QC Benefits - IILecture 18 - Basics and Applications of Reverse Phase Protein Arrays - ILecture 19 - Basics and Applications of Reverse Phase Protein Arrays - IILecture 20 - Basics and Applications of Reverse Phase Protein Arrays - IIILecture 21 - Antibody signatures defined by high-content peptide microarray analysisLecture 22 - An overview of label-free technologies - ILecture 23 - An overview of label-free technologies - IILecture 24 - Mass Spectrometry coupled Interactomics - ILecture 25 - Mass Spectrometry coupled Interactomics - IILecture 26 - Biomolecular interactions using Bio-Layer Interferometry (BLI) - ILecture 27 - Biomolecular interactions using Bio-Layer Interferometry (BLI) - IILecture 28 - Biomolecular interaction analytics using MicroScale ThermophoresisLecture 29 - Surface Plasmon Resonance- Principles and Assays - I



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Lecture 30 - Surface Plasmon Resonance- Principles and Assays - IILecture 31 - Use of SPR in unravelling domain motif interactions of proteasomal assembly chaperonesLecture 32 - Next-Generation Sequencing Technology- Ion TorrentÃ¢Lecture 33 - NGS Technology- Bioinformatics and data analysis - ILecture 34 - NGS Technology- Bioinformatics and data analysis - IILecture 35 - Next-Generation Sequencing Technology-MiSeq SystemLecture 36 - NGS target enrichment workflow for exomes, targeted panels and beyondLecture 37 - The Human Pathology AtlasLecture 38 - The Human Pathology AtlasLecture 39 - Conclusions and Overview - I (Statistical analysis - I)Lecture 40 - Conclusions and overview - II (Statistical analysis - II)



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NPTEL Video Course - Biotechnology - NOC:Introduction to Proteogenomics




Lecture 1 - Proteogenomics overview - ILecture 2 - Proteogenomics overview - IILecture 3 - Introduction to Genomics - Part ILecture 4 - Introduction to Genomics - Part IILecture 5 - Introduction to Genomics - Part IIILecture 6 - Perspectives in Proteogenomics - ILecture 7 - Advancement in Cancer GenomicsLecture 8 - Introduction to Genomics - Part IVLecture 9 - Introduction to Genomics - cBioPortalLecture 10 - Genotype, Gene expression and Phenotype - ILecture 11 - Genotype, Gene expression and Phenotype - IILecture 12 - An overview of NGS technologyLecture 13 - NGS - Sequencing by synthesis - ILecture 14 - NGS - Sequencing by synthesis - IILecture 15 - Introduction to ProteomicsLecture 16 - ProteomicsLecture 17 - Applications of ProteomicsLecture 18 - Introduction to MS-based Proteomics - ILecture 19 - Introduction to MS-based Proteomics - IILecture 20 - Applications of NGS - IonTorrentLecture 21 - Genomic Analysis using Droplet PCR - ILecture 22 - Introduction to MS-based Proteomics - I (Hands-on session)Lecture 23 - Introduction to MS-based Proteomics - II (Hands-on session)Lecture 24 - Data analysisLecture 25 - Data analysisLecture 26 - Data analysisLecture 27 - Genomic Analysis using Droplet PCR - IILecture 28 - Topics in ProteogenomicsLecture 29 - Machine learning and Clustering



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Lecture 30 - Hypothesis testingLecture 31 - ProTIGY - ILecture 32 - ProTIGY - IILecture 33 - Proteomics Data AnalysisLecture 34 - Proteomics Lab Demonstration - ILecture 35 - Proteomics Lab Demonstration - IILecture 36 - Workflow to Automated Data ProcessingLecture 37 - Introduction to Fire CloudLecture 38 - FireCloud and Data ModelLecture 39 - Bioinformatics solutions for Big Data Analysis - ILecture 40 - Bioinformatics solutions for Big Data Analysis - IILecture 41 - Introduction to Targeted ProteomicsLecture 42 - Data analysis using SkylineLecture 43 - Large-scale data Science - ILecture 44 - Large-scale data Science - IILecture 45 - Large-scale data Science - IIILecture 46 - DIA-SWATH Atlas - ILecture 47 - DIA-SWATH Atlas - IILecture 48 - Prediction AnalysisLecture 49 - Pathway Enrichment and Network AnalysisLecture 50 - Human Protein Atlas - ILecture 51 - Human Protein Atlas - IILecture 52 - Affinity based proteomics & HPALecture 53 - Clinical Considerations for OMICS - ILecture 54 - Clinical Considerations for OMICS - IILecture 55 - Topics in ProteogenomicsLecture 56 - Integrative Genomics Viewer (IGV)Lecture 57 - Introduction to Proteogenomics - ILecture 58 - Introduction to Proteogenomics - IILecture 59 - Sequence centric proteogenomicsLecture 60 - Variant AnalysisLecture 61 - Proteomics - Clinical ApplicationsLecture 62 - Perspectives in Proteogenomics - IILecture 63 - Predictive Analysis - ILecture 64 - Predictive Analysis - IILecture 65 - Association/ Marker SelectionLecture 66 - WebGestalt - ILecture 67 - WebGestalt - IILecture 68 - Perspectives in Proteogenomics - III



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Lecture 69 - Network Analysis - ILecture 70 - Network Analysis - IILecture 71 - Mutations and Signaling - ILecture 72 - Mutations and Signaling - IILecture 73 - Pathway Enrichment - ILecture 74 - Perspectives in Proteogenomics - IVLecture 75 - Pathway Enrichment - IILecture 76 - Sequence - GSEALecture 77 - Linked Omics - ILecture 78 - Linked Omics - IILecture 79 - Proteogenomics - Opportunities and ChallengesLecture 80 - Perspectives in Proteogenomics - V



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NPTEL Video Course - Biotechnology - NOC:Interactomics: Basics and Applications




Lecture 1 - Introduction to ProteomicsLecture 2 - Introduction to InteractomicsLecture 3 - High throughput platforms of interactomicsLecture 4 - Cell-free expression based protein microarraysLecture 5 - NAPPALecture 6 - NAPPA Technology and Protein Arrays - ILecture 7 - NAPPA Technology and Protein Arrays - IILecture 8 - BiomarkersLecture 9 - BiomarkersLecture 10 - BiomarkersLecture 11 - NAPPA and its applications in study of antibody immune response in disease and in drug screening - ILecture 12 - NAPPA and its applications in study of antibody immune response in disease and in drug screening - IILecture 13 - NAPPA and its applications in study of antibody immune response in disease and in drug screening - IIILecture 14 - Using functional proteomics to identify biomarkers and therapeutic targets - ILecture 15 - Using functional proteomics to identify biomarkers and therapeutic targets - IILecture 16 - Applications of protein microarrays in Malaria Research - ILecture 17 - Applications of protein microarrays in Malaria Research - IILecture 18 - Introduction to Bioprinting and IrisOptical QC Benefits - ILecture 19 - Introduction to Bioprinting and IrisOptical QC Benefits - IILecture 20 - Screening of autoantibody signatures in cancer patientsLecture 21 - Basics of Image Scanning and data acquisitionLecture 22 - Applications of protein arrays in identification of autoantibody signatures - ILecture 23 - Applications of protein arrays in identification of autoantibody signatures - IILecture 24 - Applications of protein microarrays in deciphering PTMs and biological networksLecture 25 - Basics and Applications of Reverse Phase Protein Arrays - ILecture 26 - Basics and Applications of Reverse Phase Protein Arrays - IILecture 27 - Basics and Applications of Reverse Phase Protein Arrays - IIILecture 28 - An overview of label-free technologiesLecture 29 - Surface Plasmon Resonance - Principles and Assays - I



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Lecture 30 - Surface Plasmon Resonance - Principles and Assays - IILecture 31 - Basics of SPRLecture 32 - Basics of SPRLecture 33 - Protein immobilization for protein-protein interaction studiesLecture 34 - Protein-protein interaction studyLecture 35 - Protein-protein interaction studyLecture 36 - Use of SPR in unravelling domain motif interactions of proteasomal assembly chaperonesLecture 37 - Protein-small molecule interaction studyLecture 38 - Protein-small molecule interaction studyLecture 39 - An introduction to biolayer interferometry (BLI)and its applications in protein researchLecture 40 - Biomolecular interactions using Bio-Layer Interferometry (BLI) - ILecture 41 - Biomolecular interactions using Bio-Layer Interferometry (BLI) - IILecture 42 - Lab session- An introduction to BioLayer Interferometry (BLI) and its applications in protein researchLecture 43 - Applications of label-free technologies - IILecture 44 - Biomolecular interaction analytics using MicroScale ThermophoresisLecture 45 - Mass Spectrometry coupled Interactomics - ILecture 46 - Mass Spectrometry coupled Interactomics - IILecture 47 - Next-Generation Sequencing Technology - Ion TorrentLecture 48 - NGS Technology - Bioinformatics and data analysis - ILecture 49 - NGS Technology - Bioinformatics and data analysis - IILecture 50 - Next-Generation Sequencing Technology- IlluminaLecture 51 - Agilent complete NGS target enrichment workflow for exomes, targeted panels and beyondLecture 52 - The Human Pathology AtlasLecture 53 - The Human Pathology AtlasLecture 54 - Statistical Analysis - ILecture 55 - Statistical Analysis - IILecture 56 - Secondary Data AnalysisLecture 57 - Pathway Enrichment and Network AnalysisLecture 58 - Data Repositories and DatabasesLecture 59 - Application of multi-omics approach for better understanding of cancersLecture 60 - Integrated Omics and Systems Biology- Conclusion



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NPTEL Video Course - Biotechnology - Enzyme Science and Engineering

Subject Co-ordinator - Prof. Subhash Chand

Co-ordinating Institute - IIT - Delhi


Lecture 1 - Introduction and Scope to Enzyme Science and EngineeringLecture 2 - Characteristic Features of EnzymesLecture 3 - Enzymes as BiocatalystsLecture 4 - Enzymatic CatalysisLecture 5 - Specificity of Enzyme ActionLecture 6 - Kinetics of Enzyme Catalyzed ReactionsLecture 7 - Kinetics of Enzyme Catalyzed ReactionsLecture 8 - Deviation from Hyperbolic Enzyme KineticsLecture 9 - Role of Effector Molecules in Enzyme KineticsLecture 10 - Reversible InhibitionLecture 11 - Effect of PH and Temperature on EnzymeLecture 12 - Kinetics of Bi substrate EnzymeLecture 13 - Kinetics of Bi substrate EnzymeLecture 14 - Immobilized Enzymes - ILecture 15 - Immobilized Enzymes - IILecture 16 - Immobilized Enzymes - IIILecture 17 - Immobilization of Enzymes by EntrapmentLecture 18 - Effect of ImmobilizationLecture 19 - Reactors for Enzyme Catalyzed ReactionsLecture 20 - Idealized Enzyme Reactor PerformanceLecture 21 - Idealized Enzyme Reactor PerformanceLecture 22 - Kinetic Parameters for IME SystemsLecture 23 - Steady State Analysis of Mass TransferLecture 24 - Steady State Analysis of Mass TransferLecture 25 - Non Ideal Flow in Continuous Immobilized EnzymeLecture 26 - Applications of Immobilized Enzymes in ProcessLecture 27 - Analytical ApplicationsLecture 28 - Enzyme Technology Challenges



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NPTEL Video Course - Biotechnology - NOC:Introduction to Dynamical Models in Biology

Subject Co-ordinator - Prof. Biplab Bose

Co-ordinating Institute - IIT - Guwahati


Lecture 1 - Mathematical modeling in BiologyLecture 2 - How to Start ModelingLecture 3 - Modeling the spread of infectious diseaseLecture 4 - Modeling population growthLecture 5 - Numerical solution of ODE-1Lecture 6 - Numerical solution of ODE-2Lecture 7 - Simulating ODE-based modelsLecture 8 - Simulating ODE-based modelsLecture 9 - Steady state and stability analysisLecture 10 - Steady state and stability analysisLecture 11 - Phase Plane Analysis - ILecture 12 - Phase Plane Analysis - IILecture 13 - Concepts of BifurcationLecture 14 - Concepts of BifurcationLecture 15 - Modeling Molecular Processes in CellLecture 16 - Modeling Molecular Processes in CellLecture 17 - Modeling Molecular Processes in CellLecture 18 - Modeling Molecular Processes in CellLecture 19 - Modeling Cell SignalingLecture 20 - Modeling Cell SignalingLecture 21 - Modeling Cell SignalingLecture 22 - Modeling Transcriptional Circuits-1Lecture 23 - Modeling Transcriptional Circuits-2Lecture 24 - Online Resources for Mathematical Modeling in Biology



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NPTEL Video Course - Biotechnology - NOC:Genetic Engineering: Theory and Application

Subject Co-ordinator - Dr. Vishal Trivedi

Co-ordinating Institute - IIT - Guwahati


Lecture 1 - Cellular Structure - Part ILecture 2 - Cellular Structure - Part IILecture 3 - Cellular Structure - Part IIILecture 4 - Metabolic Reactions in Biological SystemLecture 5 - Growth Media For Different Expression SystemLecture 6 - Microbial Growth KineticsLecture 7 - Isolation of a Gene Fragment - Part ILecture 8 - Isolation of a Gene Fragment - Part IILecture 9 - Isolation of a Gene Fragment - Part IIILecture 10 - Polymerase Chain ReactionLecture 11 - Molecular Tools for CloningLecture 12 - Cloning Vectors - ILecture 13 - Cloning Vectors - IILecture 14 - DNA Delivery In Host - Part ILecture 15 - DNA Delivery In Host - Part IILecture 16 - Screening of Recombinant ClonesLecture 17 - Protein Production in Host - Part 1Lecture 18 - Protein Production in Host - Part 2Lecture 19 - Protein Production in Host - Part 3Lecture 20 - Product Recovery from Host CellsLecture 21 - Basics of Chromatography - Part 1Lecture 22 - Basics of Chromatography - Part 2Lecture 23 - Ion-exchange ChromatographyLecture 24 - Hydrophobic Interaction ChromatographyLecture 25 - Gel Filtration chromatography - Part 1Lecture 26 - Gel Filtration chromatography - Part 2Lecture 27 - Affinity Chromatography - Part 1Lecture 28 - Affinity Chromatography - Part 2Lecture 29 - Affinity Chromatography - Part 3



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Lecture 30 - Affinity Chromatography - Part 4Lecture 31 - Electrophoresis - Part 1Lecture 32 - Electrophoresis - Part 2Lecture 33 - Electrophoresis - Part 3Lecture 34 - Protein SequencingLecture 35 - Spectroscopy - Part ILecture 36 - Spectroscopy - Part IILecture 37 - Biotechnology Applications - Part 1Lecture 38 - Biotechnology Applications - Part 2Lecture 39 - Biotechnology Applications - Part 3Lecture 40 - Summary and Conclusions - Part 1Lecture 41 - Summary and Conclusions - Part 2



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NPTEL Video Course - Biotechnology - Animal Physiology

Subject Co-ordinator - Prof. Mainak Das

Co-ordinating Institute - IIT - Kanpur


Lecture 1 - Animal PhysiologyLecture 2 - Animal PhysiologyLecture 3 - Animal PhysiologyLecture 4 - Animal PhysiologyLecture 5 - Animal PhysiologyLecture 6 - Animal PhysiologyLecture 7 - Animal PhysiologyLecture 8 - Animal PhysiologyLecture 9 - Animal PhysiologyLecture 10 - Animal PhysiologyLecture 11 - Animal PhysiologyLecture 12 - Animal PhysiologyLecture 13 - Animal PhysiologyLecture 14 - Animal PhysiologyLecture 15 - Animal PhysiologyLecture 16 - Animal PhysiologyLecture 17 - Animal PhysiologyLecture 18 - Animal PhysiologyLecture 19 - Animal PhysiologyLecture 20 - Animal PhysiologyLecture 21 - Animal PhysiologyLecture 22 - Animal PhysiologyLecture 23 - Animal PhysiologyLecture 24 - Animal PhysiologyLecture 25 - Animal PhysiologyLecture 26 - Animal PhysiologyLecture 27 - Animal PhysiologyLecture 28 - Animal PhysiologyLecture 29 - Animal Physiology



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Lecture 30 - Animal PhysiologyLecture 31 - Animal PhysiologyLecture 32 - Animal PhysiologyLecture 33 - Animal PhysiologyLecture 34 - Animal PhysiologyLecture 35 - Animal PhysiologyLecture 36 - Animal PhysiologyLecture 37 - Animal PhysiologyLecture 38 - Animal PhysiologyLecture 39 - Animal PhysiologyLecture 40 - Animal Physiology



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NPTEL Video Course - Biotechnology - Bio electricity




Lecture 1 - Bio electricityLecture 2 - Bio electricityLecture 3 - Bio electricityLecture 4 - Bio electricityLecture 5 - Bio electricityLecture 6 - Bio electricityLecture 7 - Bio electricityLecture 8 - Bio electricityLecture 9 - Bio electricityLecture 10 - Bio electricityLecture 11 - Bio electricityLecture 12 - Bio electricityLecture 13 - Bio electricityLecture 14 - Bio electricityLecture 15 - Bio electricityLecture 16 - Bio electricityLecture 17 - Bio electricityLecture 18 - Bio electricityLecture 19 - Bio electricityLecture 20 - Bio electricityLecture 21 - Bio electricityLecture 22 - Bio electricityLecture 23 - Bio electricityLecture 24 - Bio electricityLecture 25 - Bio electricityLecture 26 - Bio electricityLecture 27 - Bio electricityLecture 28 - Bio electricityLecture 29 - Bio electricity



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Lecture 30 - Bio electricityLecture 31 - Bio electricityLecture 32 - Bio electricityLecture 33 - Bio electricityLecture 34 - Bio electricityLecture 35 - Bio electricityLecture 36 - Bio electricityLecture 37 - Bio electricityLecture 38 - Bio electricityLecture 39 - Bio electricityLecture 40 - Bio electricity



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NPTEL Video Course - Biotechnology - NOC:Human Molecular Genetics

Subject Co-ordinator - Mr.S. Ganesh



Lecture 1 - Fundamentals of central dogma, Part 1Lecture 2 - Fundamentals of central dogma, Part 2Lecture 3 - Fundamentals of central dogma, Part 3Lecture 4 - Chromosome Structure and FunctionLecture 5 - Pedigree AnalysisLecture 6 - Complications in Mendelian Pedigree PatternsLecture 7 - DNA Cloning and Hybridization Techniques - Part 1Lecture 8 - DNA Cloning and Hybridization Techniques - Part 2Lecture 9 - Practice Session 1Lecture 10 - Practice Session 2Lecture 11 - Mutations and instability of human DNA (Part 1)Lecture 12 - Mutations and instability of human DNA (Part 2)Lecture 13 - Animal Models for Human DiseasesLecture 14 - Positional cloning of genes for monogenic disordersLecture 15 - Human Genome Project and HapMap project



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NPTEL Video Course - Biotechnology - NOC:Functional Genomics

Subject Co-ordinator - S. Ganesh



Lecture 1 - Introduction to Functional GenomicsLecture 2 - The Genomics EraLecture 3 - EpigeneticsLecture 4 - Forward Genetics vs Reverse GeneticsLecture 5 - Genome Editing Approaches - Part 1Lecture 6 - Genome Editing Approaches - Part 2Lecture 7 - Transcriptomics - Part 1Lecture 8 - Transcriptomics - Part 2Lecture 9 - Genome Sequence DatabasesLecture 10 - DNA Sequencing Methods - Part 1Lecture 11 - DNA Sequencing Methods - Part 2Lecture 12 - Applications of Next-Generation Sequencing (NGS)Lecture 13 - Tutorial - Session 1Lecture 14 - Tutorial - Session 2Lecture 15 - Genomic Insight into EvolutionLecture 16 - Genome sequenceLecture 17 - Outcome of Comparative GenomicsLecture 18 - Laboratory - Session 1Lecture 19 - Laboratory - Session 2



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NPTEL Video Course - Biotechnology - NOC:Bioenergy




Lecture 1 - IntroductionLecture 2 - Oil Economy of the WorldLecture 3 - Unit of Energy and Introduction of BioenergyLecture 4 - How Biomass Formed on the EarthLecture 5 - Road Map of BioenergyLecture 6 - Basic Biomass Technology (Resources and Production)Lecture 7 - Basics of Mechanism of Light ReactionLecture 8 - Exploration of Photosynthesis ProcessLecture 9 - In Photosynthesis Oxygen Comes from Water MoleculeLecture 10 - Hill ReactionLecture 11 - Electron Transport Process in Light ReactionLecture 12 - How Carbon dioxide converted in CarbohydrateLecture 13 - From Carbon dioxide to two Molecules of 3 - Phospho Glycerate by RUBISCOLecture 14 - RUBISCO enzymeLecture 15 - Photo respiration and Calvin CycleLecture 16 - Efficiency Calculation of Photosynthesis ProcessLecture 17 - C3 and C4 Plant Structure and Photosynthesis ProcessLecture 18 - Biomass production System and their CategorizationLecture 19 - Important Parameters for Selecting Biomass CropsLecture 20 - Factors Determining the Conversion Process - ILecture 21 - Factors Determining the Conversion Process - IILecture 22 - Factors Determining the Conversion Process - IIILecture 23 - Conversion TechnologyLecture 24 - Conversion Process- (Combustion Process)Lecture 25 - Pyrolysis ProcessLecture 26 - Classification of PyrolysisLecture 27 - Bio Oil - (Solution for Thermal Instability and Corrosivity)Lecture 28 - Spark Ignition EngineLecture 29 - Compression Ignition Engine



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Lecture 30 - Carbonization - Graphene like materialLecture 31 - Introduction of GasificationLecture 32 - Thermo Chemical Process of GasificationLecture 33 - Feed Stock Treatment of GasificationLecture 34 - Feed Stock PropertyLecture 35 - Gasification Types - Up Drift GasifierLecture 36 - Down drift and Cross Flow GasifierLecture 37 - Operation and Performance of Fixed Bed GasifierLecture 38 - Fludized Bed GasificationLecture 39 - Operation and Performance of Fluidized Bed GasifierLecture 40 - Biological Root of Gasification and Summary of Course



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NPTEL Video Course - Biotechnology - NOC:Animal Physiology




Lecture 1 - An Introduction to Anatomy and PhysiologyLecture 2 - Organization of living systemLecture 3 - Homeostasis and system integrationLecture 4 - Positive feedback loop in homeostasisLecture 5 - Chemical basis of organization of the bodyLecture 6 - Integumentary System - ILecture 7 - Integumentary system - IILecture 8 - Integumentary System - IIILecture 9 - Bone and Cartilage - ILecture 10 - Bone and Cartilage - IILecture 11 - Introduction of muscleLecture 12 - Skeletal muscle formationLecture 13 - Anatomy of skeletal muscleLecture 14 - Contraction in muscleLecture 15 - Function of actin and myosinLecture 16 - Length tension relationship of skeletal muscleLecture 17 - Excitation contraction coupling with nervous systemLecture 18 - Stretch reflex phenomenaLecture 19 - Nervous system anatomy and signalingLecture 20 - Structure and circuit of neuronsLecture 21 - Origin of biological cellLecture 22 - Excitability in cellLecture 23 - Ion transportation in the cellLecture 24 - Signal propagation in neuronsLecture 25 - Neurotransmitter and action potentialLecture 26 - Spatial temporal summation of signal in mesh neuronsLecture 27 - Anatomy of Hippo-campusLecture 28 - Epilepsy and memoryLecture 29 - Long term potentiation



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Lecture 30 - Long term depressionLecture 31 - Alzheimers diseaseLecture 32 - Parkinsons diseaseLecture 33 - Amyotrophic lateral sclerosisLecture 34 - Spinal cord injuryLecture 35 - Glial cellsLecture 36 - Stretch reflex circuit - ILecture 37 - Stretch reflex arc circuit - IILecture 38 - Neuro muscular junctionLecture 39 - Hearing systemLecture 40 - Olfaction system



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NPTEL Video Course - Biotechnology - NOC:Cell Culture Technologies




Lecture 1 - Introduction of Cell Culture TechnologyLecture 2 - Philosophy and complexity in cell cultureLecture 3 - To grow the cell outside the bodyLecture 4 - Cell cycle conceptLecture 5 - Dividing cellsLecture 6 - Biology of cell cultureLecture 7 - Layout(s) and design(s) of cell culture facilityLecture 8 - Precautions during designing the lab layout - ILecture 9 - Precautions during designing the lab layout - IILecture 10 - Precautions during designing the lab layout - IIILecture 11 - State of the art facility in cell culture lab - ILecture 12 - State of the art facility in cell culture lab - IILecture 13 - Specialized facility in cell culture labLecture 14 - Interaction of cell and glass/polycorbonate surface - ILecture 15 - Interaction of cell and glass/polycorbonate surface - IILecture 16 - Poly D lysine depositionLecture 17 - Surface chemical analysisLecture 18 - Cell growth processLecture 19 - Cell surface interfaceLecture 20 - Cell culture substrate patterningLecture 21 - Introduction of define systemLecture 22 - Mechanical dissociation of hippocampal tissueLecture 23 - Rules for mechanical dissociation of tissueLecture 24 - Drum molecule testingLecture 25 - Adult hippocampal neuron dissociationLecture 26 - Cell separation and In vitro myelination cell culture mode - ILecture 27 - Cell separation and In vitro myelination cell culture mode - IILecture 28 - Cell separation and In vitro myelination cell culture mode - IIILecture 29 - Cell Separation and In vitro myelination cell culture mode - IV



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Lecture 30 - Cell separation and in vitro myelination cell culture mode - VLecture 31 - Fluorescent assisted cell sortingLecture 32 - Condition for regenerated cellsLecture 33 - Introduction of skeletal muscle cell cultureLecture 34 - Skeletal muscle cell cultureLecture 35 - Cardiac muscle cell cultureLecture 36 - Advance cell culture modules - ILecture 37 - Advance cell culture modules - IILecture 38 - Advance cell culture modules - IIILecture 39 - Advance cell culture modules - IVLecture 40 - Advance cell culture modules - V



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NPTEL Video Course - Biotechnology - NOC:Forest Biometry

Subject Co-ordinator - Prof. Mainak Das, Dr. Ankur Awadhiya



Lecture 1 - IntroductionLecture 2 - Recap of formulaeLecture 3 - Recap of trigonometryLecture 4 - Measurment of central tendency and dispersionLecture 5 - Graphical presentation of dataLecture 6 - Shape of a treeLecture 7 - Metzgers theoryLecture 8 - Form factor and form quotientsLecture 9 - Taper equationsLecture 10 - Making the cutsLecture 11 - Cross-section of a treeLecture 12 - Where to measure the diameterLecture 13 - Callipers - Usages and IssuesLecture 14 - TapeLecture 15 - Measurement of bark and growth ringsLecture 16 - Tree heightLecture 17 - Method of similar trianglesLecture 18 - Distance measurementsLecture 19 - Angular measurementLecture 20 - LIDARLecture 21 - Canopy attributes - Part ILecture 22 - Canopy attributes - Part IILecture 23 - Canopy attributes - Part IIILecture 24 - Canopy cover and closureLecture 25 - PhotogrammetryLecture 26 - Basal area of a tree and standLecture 27 - Stand basal area, crop diameter and crop ageLecture 28 - Point sampling - ILecture 29 - Point sampling - II



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Lecture 30 - Number density and sample calculationsLecture 31 - VolumeLecture 32 - The Quarter - girth formulaLecture 33 - Volume computations in the fieldLecture 34 - Volume TableLecture 35 - Forest SamplingLecture 36 - Density and mass measurementLecture 37 - Normalized difference vegetation Index (NDVI)Lecture 38 - Site qualityLecture 39 - Recap - ILecture 40 - Recap - II



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NPTEL Video Course - Biotechnology - NOC:Introduction to Professional and Scientific Communication

Subject Co-ordinator - Mr. S. Ganesh



Lecture 1 - Introduction to the topicLecture 2 - Where do research ideas come from?Lecture 3 - Inductive vs Deductive ReasoningLecture 4 - Scientific HypothesisLecture 5 - Scientific Hypothesis (Continued...)Lecture 6 - Testing the HypothesisLecture 7 - Introduction to Scientific WritingLecture 8 - Writing an AbstractLecture 9 - Title for a Research PaperLecture 10 - Title and KeywordsLecture 11 - Mileposts for the Article WritingLecture 12 - Writing the Methods SectionLecture 13 - Writing the Results SectionLecture 14 - Writing Results Section (Continued...)Lecture 15 - How to Prepare FiguresLecture 16 - How to Prepare SchematicsLecture 17 - How to write Introduction and Discussion SectionsLecture 18 - Finalizing the Manuscript and Ethics in ResearchLecture 19 - Writing a Research Proposal and Preparing for a PresentationLecture 20 - Tutorial Session



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NPTEL Video Course - Biotechnology - NOC:Bioelectrochemistry




Lecture 1 - Basic Concepts - ILecture 2 - Basic Concepts - IILecture 3 - Key TermsLecture 4 - Galvanic Cells - ILecture 5 - Galvanic Cells - IILecture 6 - Salt BridgeLecture 7 - Standard Potentials - ILecture 8 - Standard Potentials - IILecture 9 - Standard Potentials - IIILecture 10 - Nernst EquationLecture 11 - Relationship between Standard electrode potential (EÂ°) and Equilibrium constant (K)Lecture 12 - Cell as chemical probe and Biochemist's formal potentialLecture 13 - Concept of Concentration Cell - ILecture 14 - Concept of Concentration Cell - IILecture 15 - Bio-electrochemistry of excitable cells (nerve cells)Lecture 16 - Types of electrodesLecture 17 - Critical care profile and metal electrodeLecture 18 - pH measurementLecture 19 - Redox indicators amperometryLecture 20 - Redox proteins, Metalloproteins and Cyclic Voltammetry



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NPTEL Video Course - Biotechnology - NOC:Bioenergetics of Life Processes




Lecture 1 - Bioenergetics of Life ProcessesLecture 2 - BioenergeticsLecture 3 - Iron-Sulfur worldLecture 4 - Evolution of complex cellular membranesLecture 5 - Charge transfer across membraneLecture 6 - Biological order and energy - ILecture 7 - Biological order and energy - IILecture 8 - Biological order and energy - IIILecture 9 - Summary of thermodynamical parameters - ILecture 10 - Summary of thermodynamical parameters - IILecture 11 - Photosynthesis - ILecture 12 - Photosynthesis - IILecture 13 - Photosynthesis - IIILecture 14 - Photosynthesis - IVLecture 15 - Photosynthesis - VLecture 16 - Photosynthesis - VILecture 17 - Photosynthesis - VIILecture 18 - Photosynthesis - VIIILecture 19 - ATP SynthesisLecture 20 - Mitochondria and Chemiosmotic hypothesis



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NPTEL Video Course - Biotechnology - NOC:WildLife Conservation

Subject Co-ordinator - Dr. Ankur Awadhiya



Lecture 1 - PreliminariesLecture 2 - A closer look at BiodiversityLecture 3 - Economics Valuation of BiodiversityLecture 4 - Threats to BiodiversityLecture 5 - PreliminariesLecture 6 - Basics of SamplingLecture 7 - Distance Sampling - ILecture 8 - Distance Sampling - IILecture 9 - Radio-telemetryLecture 10 - Behavioural monitoringLecture 11 - What is a habitatLecture 12 - Habitat degradation, loss, fragmentation and displacementLecture 13 - Reserve selection and designLecture 14 - Habitat management and improvementLecture 15 - Some terminologiesLecture 16 - Some common wildlife diseasesLecture 17 - Principles of disease managementLecture 18 - PreliminariesLecture 19 - Mechanical captureLecture 20 - Chemical captureLecture 21 - Capture myopathyLecture 22 - Care of immobilised animalLecture 23 - Legal aspects of capture and restraintLecture 24 - Other topics in capture and restraintLecture 25 - Preliminaries and introduction to geneticsLecture 26 - Population geneticsLecture 27 - Chromosomal and genetic disorders, inbreedingLecture 28 - Population viability analysisLecture 29 - Reintroductions and outbreeding



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Lecture 30 - FundamentalsLecture 31 - Zoos and their managementLecture 32 - Botanical gardensLecture 33 - Other aspectsLecture 34 - Impacts of climate changeLecture 35 - Plastics and biodiversityLecture 36 - Oil spillsLecture 37 - Crisis and learningsLecture 38 - Revision - ILecture 39 - Revision - IILecture 40 - Revision - III



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NPTEL Video Course - Biotechnology - NOC:Nanotechnology in Agriculture




Lecture 1 - IntroductionLecture 2 - What is NanotechnologyLecture 3 - An outlineLecture 4 - AgricultureLecture 5 - Modern AgricultureLecture 6 - A RestartLecture 7 - Classifying nanomaterials Based on Shape and GeometryLecture 8 - Classifying Nanomaterials Based on Chemical NatureLecture 9 - Physical Approaches to Nanomaterial SynthesisLecture 10 - Biological and Chemical Approaches to Nanomaterial SynthesisLecture 11 - Detailed Physical Techniques - ILecture 12 - Detailed Physical Techniques - IILecture 13 - Detailed Chemical TechniquesLecture 14 - Detailed Biological TechniquesLecture 15 - Basic Characterisation Techniques of NanomaterialsLecture 16 - Characterisation techniques for physical and chemical surface properties of a materialLecture 17 - Nanomaterials in AgricultureLecture 18 - Iron pyrite and seed pre-treatmentLecture 19 - nano-Pyrite and its lab trial with chickpeaLecture 20 - nano-Pyrite field trial with spinach and its mechanistic detailsLecture 21 - Mechanistic details of the action of Pyrite nano-particleLecture 22 - Application of Pyrite nano-particle in different cropsLecture 23 - Application of different nano-particles in Agriculture - ILecture 24 - Benefits of nanoparticles in AgricultureLecture 25 - Nanotechnology in animal productionLecture 26 - Antioxidant nanomaterial in animal production - ILecture 27 - Antioxidant nanomaterial in animal production - IILecture 28 - Antioxidant nanomaterial in animal production - IIILecture 29 - Antioxidant nanomaterial in skeletal muscle development - I



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Lecture 30 - Antioxidant nanomaterial in skeletal muscle development - IILecture 31 - Skeletal muscle development and nanomaterial interventionLecture 32 - Fabrication of nano-micro devices to study force generation in musclesLecture 33 - Summarising role of nanomaterials in animal productionLecture 34 - Nanomaterials in food processing and preservation - ILecture 35 - Nanomaterials in food processing and preservation - IILecture 36 - Multifunctionality of nanomaterialLecture 37 - Futuristic multifunctional, sustainable and green nanomaterialLecture 38 - Case study of Titanium dioxide - ILecture 39 - Case study of Titanium dioxide - IILecture 40 - The future



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NPTEL Video Course - Biotechnology - NOC:Wild Life Ecology

Subject Co-ordinator - Dr. Ankur Awadhiya, Prof. Mainak Das



Lecture 1 - Introduction to the courseLecture 2 - A historical overview of EcologyLecture 3 - Ecology and EvolutionLecture 4 - The levels of organisationLecture 5 - Species abundance and compositionLecture 6 - Biodiversity - IILecture 7 - Positive InteractionsLecture 8 - Negative InteractionsLecture 9 - Study of Behaviour and Behavioral EcologyLecture 10 - Food chains, Food webs and trophic levelsLecture 11 - Primary ProductionLecture 12 - Nutrient CyclesLecture 13 - Population parameters and demographic techniquesLecture 14 - Population growth and regulationLecture 15 - Population studies and applicationsLecture 16 - Community nature and parametersLecture 17 - Community changes and ecological successionLecture 18 - Community organisationLecture 19 - BiographyLecture 20 - Why are things where they are?Lecture 21 - Some push and pull factors in greater detailLecture 22 - Threats to speciesLecture 23 - In-situ conservationLecture 24 - Ex-situ conservationLecture 25 - Introduction and impactsLecture 26 - Human population growth and food requirementsLecture 27 - Sustainable developmentLecture 28 - Oil spillsLecture 29 - Plastic and biodiversity



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Lecture 30 - Impacts of climate changeLecture 31 - Optimum yield problemLecture 32 - Biological controlLecture 33 - Ecotoxicology and pollution management, Restoration ecologyLecture 34 - RevisionLecture 35 - RevisionLecture 36 - Revision



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NPTEL Video Course - Biotechnology - NOC:Forests and their Management

Subject Co-ordinator - Dr. Ankur Awadhiya



Lecture 1 - What is a forest ?Lecture 2 - Classification of forestsLecture 3 - Value of forestsLecture 4 - What is Silviculture ?Lecture 5 - Plant Growth FactorsLecture 6 - Ecological SuccessionLecture 7 - Soil and Soil ProfileLecture 8 - Major Soil TypesLecture 9 - Nutrient CyclesLecture 10 - Tree FormLecture 11 - Measurement of Tree attributes - ILecture 12 - Measurement of Tree attributes - IILecture 13 - Classical ToolsLecture 14 - PhotogrammetryLecture 15 - LiDARLecture 16 - Kinds of ThreatsLecture 17 - Forest FireLecture 18 - Forest LawLecture 19 - RegenerationLecture 20 - Silvicultureal SystemsLecture 21 - Clear Felling SystemLecture 22 - Shelterwood System - ILecture 23 - Shelterwood System - IILecture 24 - Selection System and Irregular Shelterwood SystemLecture 25 - Logging and ProcessingLecture 26 - Growing Stock and IncrementLecture 27 - Yield and Sustained YieldLecture 28 - Seed Collection and TreatmentLecture 29 - Nursery Techniques



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Lecture 30 - Planting and TendingLecture 31 - NTFPLecture 32 - Social Forestry and Tribal WelfareLecture 33 - Conservation of Wild AnimalsLecture 34 - Revision - Part 1Lecture 35 - Revision - Part 2Lecture 36 - Revision - Part 3



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NPTEL Video Course - Chemistry and Biochemistry - BioChemistry I

Subject Co-ordinator - Prof. S. Dasgupta

Co-ordinating Institute - IIT - Kharagpur


Lecture 1 - Amino Acids - ILecture 2 - Amino Acids - IILecture 3 - Protein Structure - ILecture 4 - Protein structure - IILecture 5 - Protein Structure - IIILecture 6 - Protein Structure - IVLecture 7 - Enzymes - ILecture 8 - Enzymes - IILecture 9 - Enzymes - IIILecture 10 - Enzymes Mechanisms - ILecture 11 - Enzymes Mechanisms - IILecture 12 - Myoglobin and HemoglobinLecture 13 - Lipids and Membranes - ILecture 14 - Lipids and Membranes - IILecture 15 - Membrane TransportLecture 16 - Carbohydrates - ILecture 17 - Carbohydrates - IILecture 18 - Vitamins and Coenzymes - ILecture 19 - Vitamins and Coenzymes - IILecture 20 - Nucleic Acids - ILecture 21 - Nucleic Acids - IILecture 22 - Nucleic Acids - IIILecture 23 - Bioenergetics - ILecture 24 - Bioenergetics - IILecture 25 - Metabolism - ILecture 26 - Metabolism - IILecture 27 - Metabolism - IIILecture 28 - Overview of the Course



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NPTEL Video Course - Biotechnology - NOC:Industrial Biotechnology

Subject Co-ordinator - Prof. Debabrata Das



Lecture 1 - Industrial BiotechnologyLecture 2 - Development of industrial strainLecture 3 - Medium characteristics and biochemical pathwaysLecture 4 - Chemical reaction kineticsLecture 5 - Chemical reaction analysis (Continued...)Lecture 6 - Different types of reactorsLecture 7 - Reactor analysisLecture 8 - Reactor analysis (Continued...)Lecture 9 - Stoichiometry of bioprocessesLecture 10 - Stoichiometry of bioprocesses (Continued...)Lecture 11 - Enzymatic reaction KineticsLecture 12 - Enzymatic reaction Kinetics (Continued...)Lecture 13 - Immobilization techniquesLecture 14 - Immobilization techniques (Continued...)Lecture 15 - Life cycle of the microbial cell, Microbial growth kinetics, product formation and substrate degradationLecture 16 - Microbial growth kinetics, product formation and substrate degradation (Continued...)Lecture 17 - Microbial growth kinetics, product formation and substrate degradation (Continued...)Lecture 18 - Overview of the fermenterLecture 19 - Flow diagrams and pumps and valves used in fermentation industriesLecture 20 - Flow diagrams and pumps and valves used in fermentation industries (Continued...)Lecture 21 - Upstream processingLecture 22 - Upstream processingLecture 23 - Upstream processingLecture 24 - Downstream processingLecture 25 - Downstream processingLecture 26 - Downstream processingLecture 27 - Ethanol fermentationLecture 28 - Ethanol fermentation (Continued...)Lecture 29 - Brewing industry



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Lecture 30 - Brewing industry (Continued...)Lecture 31 - Wine industryLecture 32 - Vinegar productionLecture 33 - Citric acid productionLecture 34 - Citric acid production (Continued...)Lecture 35 - Citric acid production (Continued...)Lecture 36 - Lactic acid productionLecture 37 - Lactic acid production (Continued...)Lecture 38 - Glutamic acid productionLecture 39 - Penicillin productionLecture 40 - Penicillin production (Continued...)Lecture 41 - Cephalosporin productionLecture 42 - Streptomycin productionLecture 43 - Bakerâ��s yeast fermentationLecture 44 - Bakerâ��s yeast fermentation (Continued...)Lecture 45 - Fodder yeast productionLecture 46 - Spirulina productionLecture 47 - Alpha amylase productionLecture 48 - High fructose corn syrup productionLecture 49 - Metal leachingLecture 50 - Cheese productionLecture 51 - Cheese production (Continued...)Lecture 52 - Biodiesel productionLecture 53 - Butanol productionLecture 54 - BiofertilizerLecture 55 - Aerobic effluent treatment processLecture 56 - Aerobic effluent treatment process (Continued...)Lecture 57 - Anaerobic effluent treatment processLecture 58 - Anaerobic effluent treatment processLecture 59 - 10 m^3 Pilot Plant operation for Biohydrogen productionLecture 60 - Summary and conclusion



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NPTEL Video Course - Biotechnology - NOC:Aspects Of Biochemical Engineering

Subject Co-ordinator - Prof. Debabrata Das



Lecture 1 - IntroductionLecture 2 - Microbiology - ILecture 3 - Microbiology - IILecture 4 - Fundamentals of BiochemistryLecture 5 - Bioproducts and their market valuesLecture 6 - Stoichiometry of Biochemical Processes - ILecture 7 - Stoichiometry of Biochemical Processes - IILecture 8 - Stoichiometry of Biochemical Processes - IIILecture 9 - Reaction Thermodynamics - ILecture 10 - Reaction Thermodynamics - IILecture 11 - Kinetics of homogeneous chemical reactions - ILecture 12 - Kinetics of homogeneous chemical reactions - IILecture 13 - Kinetics of homogeneous chemical reactions - IIILecture 14 - Kinetics of homogeneous chemical reactions - IVLecture 15 - Kinetics of homogeneous chemical reactions - VLecture 16 - Different types of reactorsLecture 17 - Reactor analysis - ILecture 18 - Reactor analysis - IILecture 19 - Reactor analysis - IIILecture 20 - Reactor analysis - IVLecture 21 - Kinetics of enzyme catalyzed reactions using free enzymes - ILecture 22 - Kinetics of enzyme catalyzed reactions using free enzymes - IILecture 23 - Kinetics of enzyme catalyzed reactions using free enzymes - IIILecture 24 - Kinetics of enzyme catalyzed reactions using free enzymes - IVLecture 25 - Kinetics of enzyme catalyzed reactions using free enzymes - VLecture 26 - Kinetics of enzyme catalyzed reactions using free enzymes - VILecture 27 - Immobilization of Enzymes - ILecture 28 - Immobilization of Enzymes - IILecture 29 - Kinetics of enzyme catalyzed reactions using immobilized enzymes - I



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Lecture 30 - Kinetics of enzyme catalyzed reactions using immobilized enzymes - IILecture 31 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - ILecture 32 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - IILecture 33 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - IIILecture 34 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - IVLecture 35 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - VLecture 36 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - VILecture 37 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - VIILecture 38 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - VIIILecture 39 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - IXLecture 40 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - XLecture 41 - Kinetics of substrate utilization, product formation and biomass production of microbial cells - XILecture 42 - Design and analysis of activated sludge process - ILecture 43 - Design and analysis of activated sludge process - IILecture 44 - Design and analysis of anaerobic digestion processLecture 45 - Scale up of Bioreactor - ILecture 46 - Scale up of Bioreactor - IILecture 47 - Transport Phenomenon in Bioprocess - ILecture 48 - Transport Phenomenon in Bioprocess - IILecture 49 - Transport Phenomenon in Bioprocess - IIILecture 50 - Transport Phenomenon in Bioprocess - IVLecture 51 - Air sterilization - ILecture 52 - Air sterilization - IILecture 53 - Medium sterilization - ILecture 54 - Medium sterilization - IILecture 55 - Operation of industrial fermenter and material analysisLecture 56 - Process control of the biochemical processesLecture 57 - Downstream processing - ILecture 58 - Downstream processing - IILecture 59 - Economic analysis of the biochemical processesLecture 60 - Summary and Conclusion



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NPTEL Video Course - Biotechnology - NOC:Biomicrofluidics

Subject Co-ordinator - Prof. Tapas Kumar Maiti, Prof. Suman Chakraborty



Lecture 1 - Introduction to BiomicrofluidicsLecture 2 - Introduction to Biomicrofluidics (Continued...)Lecture 3 - Engineers' guide to the cellLecture 4 - Fluidics in living systems and mechanobiologyLecture 5 - Pressure Driven FlowsLecture 6 - Surface tension driven flowsLecture 7 - Modulating surface tensionLecture 8 - Lab on a CDLecture 9 - Introduction to Electrokinetics - Part ILecture 10 - Introduction to Electrokinetics - Part IILecture 11 - Microfluidic cell culture - Part ILecture 12 - Microfluidic cell culture - Part IILecture 13 - On-chip cellular assay techniques - Part ILecture 14 - On-chip cellular assay techniques - Part IILecture 15 - Microfluidics for understanding biologyLecture 16 - Organ-on-a-chipLecture 17 - Lab-on-a-chip for genetic analysisLecture 18 - Microfluidic technology for monoclonal antibody productionLecture 19 - Microfluidics for HealthcareLecture 20 - Microfluidics for Healthcare



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NPTEL Video Course - Biotechnology - Downstream Processing

Subject Co-ordinator - Prof. Mukesh Doble

Co-ordinating Institute - IIT - Madras


Lecture 1 - IntroductionLecture 2 - Mass Balance, Heat Balance, Flow sheetLecture 3 - CostingLecture 4 - Costing (Continued...) Physical and Chemical Principles in Down StreamLecture 5 - Problems in Mass Balance, Flow sheetLecture 6 - Cell BreakageLecture 7 - Cell Breakage (Continued...)Lecture 8 - Solid Liquid SeparationLecture 9 - Solid Liquid Separation (Continued...)Lecture 10 - Solid Liquid Separation - ProblemsLecture 11 - Pre-Treatment and FiltersLecture 12 - AdsorptionLecture 13 - Adsorption (Continued...)Lecture 14 - Adsorption (Continued...)Lecture 15 - Adsorption (Continued...)Lecture 16 - Liquid Liquid ExtractionLecture 17 - Liquid Liquid Extraction (Continued...)Lecture 18 - Liquid Liquid Extraction (Continued...)Lecture 19 - Liquid Liquid Extraction (Continued...)Lecture 20 - Reversed Micellar and Aqueous Two Phase ExtractionLecture 21 - MembranesLecture 22 - Membranes (Continued...)Lecture 23 - Membranes (Continued...)Lecture 24 - Membranes (Continued...)Lecture 25 - PrecipitationLecture 26 - ChromatographyLecture 27 - Chromatography (Continued...)Lecture 28 - Chromatography (Continued...)Lecture 29 - Chromatography (Continued...)



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Lecture 30 - Chromatography (Continued...)Lecture 31 - Chromatography (Continued...)Lecture 32 - Chromatography (Continued...)Lecture 33 - HPLCLecture 34 - HPLCLecture 35 - CrystallisationLecture 36 - DryingLecture 37 - Drying and DistillationLecture 38 - Stabilisation, Utilities and Other Auxiliary Processes And AbsorptionLecture 39 - Absorption, Electrophoresis/SDS PAGELecture 40 - Future Trends, Summary of Course



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NPTEL Video Course - Biotechnology - Thermodynamics

Subject Co-ordinator - Prof. G.K. Suraishkumar



Lecture 1 - Introduction and ReviewLecture 2 - Need for Analysis Additional Thermodynamic Functions State and Path VariablesLecture 3 - Equations for a Closed system Chemical Potential Concept Gibbs-Duhem EquationLecture 4 - Maxwellâ��s relationsLecture 5 - Inter-Relationships between Thermodynamic VariablesLecture 6 - Some Useful Mathematical ManipulationsLecture 7 - Thermodynamic Relations for a Closed System with 1 mole of a pure SubstancesLecture 8 - Maximum Work,Lost Work Review of Closed SystemsLecture 9 - Open SystemsLecture 10 - Equations of State - Virial EquationsLecture 11 - Equations of State - Cubic EquationsLecture 12 - Volume EstimationLecture 13 - Volume Estimation (Continued...) Generalized correlationsLecture 14 - Generalized correlations (Continued...) Residual PropertiesLecture 15 - Residual Properties (Continued...)Lecture 16 - Generalized Correlations and Residual PropertiesLecture 17 - Fugacity Coefficient EstimationLecture 18 - Review of Module 3Lecture 19 - Learning Aspects Chemical Potential FormulationsLecture 20 - Lewis and Randall rule partial Molar PropertiesLecture 21 - Partial Molar Property Estimation from Mixing ExperimentsLecture 22 - Partial Molar Property Estimation (Continued...) Excess PropertyLecture 23 - Activity Coefficient from Excess PropertyLecture 24 - Activity Coefficient from Excess Property (Continued...)Lecture 25 - Activity Coefficient from Excess Property (Continued...) Models for Activity Coefficient in Binary SystemsLecture 26 - Models for Activity Coefficient in Binary Systems (Continued...)Lecture 27 - Review of Module 4Lecture 28 - Criteria for Phase Equilibrium Phase Rule for Non-reacting BiosystemsLecture 29 - Clausius - Clayperon Equation



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Lecture 30 - Clausius - Clayperon Equation (Continued...) vapour-Liquid EquilibriumLecture 31 - Vapour-Liquid Equilibrium (Continued...) Estimation of Fugacity coefficient from Equilibrium P-V-T DataLecture 32 - Liquid/Liquid and Solid/Liquid EquilibriaLecture 33 - Review of Module 5Lecture 34 - Criteria for Bio-reaction EquilibriaLecture 35 - Phase rule for Reacting Biosystems Equilibrium constantsLecture 36 - Effect of Temperature and Pressure on the Equilibrium constantsLecture 37 - Reaction in Liquid or Solid PhasesLecture 38 - Free energy Changes for some BioreactionsLecture 39 - ElectrolytesLecture 40 - Course Review



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NPTEL Video Course - Biotechnology - NOC:Principles of Downstream techniques in Bioprocess




Lecture 1 - IntroductionLecture 2 - Mass balance, Heat Balance, Flow sheetLecture 3 - CostingLecture 4 - Cell BreakageLecture 5 - Solid Liquid SeparationLecture 6 - Pre-treatment and Filters/centrifugeLecture 7 - Liquid-Liquid ExtractionLecture 8 - Liquid-Liquid extraction (Continued...)Lecture 9 - AdsorptionLecture 10 - Reversed micellar and aqueous two phase extractionLecture 11 - MembranesLecture 12 - Membranes (Continued...)Lecture 13 - Product stabilization, Drying, LyophilisationLecture 14 - Precipitation and crystallizationLecture 15 - Electrophoresis / SDS PAGELecture 16 - ChromatographyLecture 17 - Chromatography (Continued...1)Lecture 18 - Chromatography (Continued...2)Lecture 19 - Chromatography (Continued...3)Lecture 20 - Future trends, Other downstream operations/Summary of the course



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NPTEL Video Course - Biotechnology - NOC:Biostatistics and Design of Experiments




Lecture 1 - IntroductionLecture 2 - Experimental Design StrategyLecture 3 - Data typesLecture 4 - Poisson DistributionLecture 5 - Normal DistributionLecture 6 - Standardized Normal Distribution / t-distributionLecture 7 - t-distribution/confidence intervalLecture 8 - Statistical testsLecture 9 - t-TestLecture 10 - t-TestsLecture 11 - t-testLecture 12 - F-testsLecture 13 - F-testsLecture 14 - ANOVALecture 15 - ANOVALecture 16 - AnovaLecture 17 - AnovaLecture 18 - AnovaLecture 19 - AnovaLecture 20 - AnovaLecture 21 - Normality test / Odds ratioLecture 22 - Chi square distributionLecture 23 - Chi square distribution / testLecture 24 - Chi square testLecture 25 - Chi square test and Weibull DistributionLecture 26 - Weibull DistributionLecture 27 - Weibull distribution.Lecture 28 - Non-parametric testLecture 29 - Non parametric test/homogeneity of variance / beta distribution



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Lecture 30 - Exponential / hypergeometric distributionsLecture 31 - Hypergeometric / Log norma distributionLecture 32 - Design of experiments (DOE) - IntroductionLecture 33 - Factorial DesignLecture 34 - Full factorial designLecture 35 - Fractional factorial designLecture 36 - Other designsLecture 37 - Second order designsLecture 38 - Second order designLecture 39 - Regression analysisLecture 40 - Control charts



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NPTEL Video Course - Biotechnology - NOC:Bioreactors

Subject Co-ordinator - Prof. G.K. Suraishkumar



Lecture 1 - IntroductionLecture 2 - SterilizationLecture 3 - Solution to PP 1.1Lecture 4 - Some important conceptsLecture 5 - Enzyme bioreactors, enzyme kineticsLecture 6 - Solution to PP 2.1Lecture 7 - Inhibited enzyme kineticsLecture 8 - Solution to PP 2.2Lecture 9 - Measurement principles and methodsLecture 10 - Batch growth kineticsLecture 11 - Solution to PP 3.1Lecture 12 - Bioreactor analysisLecture 13 - Solution to PP 3.2Lecture 14 - Bioreactor environment parametersLecture 15 - Bioreactor env. par. (DO)Lecture 16 - Solution to PP 4.1Lecture 17 - Shear stress, scale-up, scale-downLecture 18 - Cell viewLecture 19 - Solution to PP 5.1Lecture 20 - Culture status, metabolic flux analysisLecture 21 - Course summary



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NPTEL Video Course - Biotechnology - NOC:Medical Biomaterials




Lecture 1 - Introduction to BiomaterialsLecture 2 - Background historyLecture 3 - HistoryLecture 4 - Properties - Mechanical and Physico-chemicalLecture 5 - Properties - Mechanical and Physico-chemicalLecture 6 - Mechanical propertiesLecture 7 - Mechanical Properties (Continued...)Lecture 8 - Resorbability, biodegradationLecture 9 - Resorbability, biodegradation (Continued...)Lecture 10 - BiofilmLecture 11 - Biofilm (Continued...)Lecture 12 - Biofilm (Continued...)Lecture 13 - Biofilm (Continued...)Lecture 14 - Material characterization - Analytical instrumentsLecture 15 - Analytical instrumentsLecture 16 - Analytical instruments (Continued...)Lecture 17 - Analytical instruments (Continued...)Lecture 18 - Biological responses, compatibility, cytotoxicityLecture 19 - Proteins, Tissue and blood ResponseLecture 20 - Cell-biomaterial interactionLecture 21 - Animal trials (in vivo)Lecture 22 - Animal trialsLecture 23 - Metals-types, classifications, applicationsLecture 24 - Metals - propertiesLecture 25 - Metals - properties (Continued...)Lecture 26 - Metals - properties (Continued...)Lecture 27 - MetalsLecture 28 - Polymers-types, classifications, applicationsLecture 29 - Polymers



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Lecture 30 - Polymers (Continued...)Lecture 31 - Polymer blendsLecture 32 - Natural biopolymersLecture 33 - Natural biopolymers - (Continued...)Lecture 34 - Biopolymers- proteins / hydrogelsLecture 35 - HydrogelsLecture 36 - ExperimentsLecture 37 - surface modification-DemonstrationLecture 38 - CeramicsLecture 39 - Cardiovascular and ocular biomaterialsLecture 40 - Sterilisation/Device failure



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NPTEL Video Course - Biotechnology - NOC:BioInformatics - Algorithms and Applications

Subject Co-ordinator - Prof. M. Michael Gromiha



Lecture 1 - Concepts and importance of BioinformaticsLecture 2 - Complexities in biological systemsLecture 3 - DNA sequence analysisLecture 4 - Sequence based parametersLecture 5 - DatabaseLecture 6 - Database categoriesLecture 7 - Protein structure and function - ILecture 8 - Protein structure and function - IILecture 9 - Protein sequence databases - ILecture 10 - Protein sequence databases - IILecture 11 - Pairwise alignment - ILecture 12 - Pairwise alignment - IILecture 13 - Uniprot DemoLecture 14 - Sequence alignment - ILecture 15 - Sequence alignment - IILecture 16 - Sequence alignmentLecture 17 - Sequence alignmentLecture 18 - Conservation score - ILecture 19 - Conservation score - IILecture 20 - Blast DemoLecture 21 - Phylogenetic trees - ILecture 22 - Phylogenetic trees - IILecture 23 - Protein sequence analysis - ILecture 24 - Protein sequence analysis - IILecture 25 - Hydrophobicity profilesLecture 26 - Patterns and PSSM profilesLecture 27 - Construction of Non-redundant datasets - ILecture 28 - Non-redundant datasets - IILecture 29 - Protein secondary structure



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Lecture 30 - Secondary structure prediction - ILecture 31 - Secondary structure prediction - IILecture 32 - Secondary structure prediction - IIILecture 33 - Protein tertiary structure - ILecture 34 - Protein tertiary structure - IILecture 35 - Protein structure analysis - ILecture 36 - Protein structure analysis - IILecture 37 - Protein structure analysis - IIILecture 38 - DemoLecture 39 - Protein structure analysis - IVLecture 40 - Protein structure prediction - ILecture 41 - Protein structure prediction - IILecture 42 - Protein stability - ILecture 43 - Protein stability - IILecture 44 - DemoLecture 45 - Stabilizing residuesLecture 46 - Thermodynamic databaseLecture 47 - Stability of proteins upon mutations - ILecture 48 - Stability of proteins upon mutations - IILecture 49 - DemoLecture 50 - Protein folding rate - ILecture 51 - Protein folding rate - IILecture 52 - Protein interactions - ILecture 53 - Protein interactions - IILecture 54 - Computer aided drug design - ILecture 55 - Computer aided drug design - IILecture 56 - Virtual screening - ILecture 57 - Virtual screening - IILecture 58 - QSAR - ILecture 59 - QSAR - IILecture 60 - DemoLecture 61 - awk programming - ILecture 62 - awk programming - IILecture 63 - Development of algorithms - ILecture 64 - Development of algorithms - IILecture 65 - Applications of bioinformatics - ILecture 66 - Applications of bioinformatics - IILecture 67 - Overview - ILecture 68 - Overview - II



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Lecture 69 - Demo



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NPTEL Video Course - Biotechnology - NOC:Demystifying the Brain

Subject Co-ordinator - Dr. V Srinivasa Chakravarthy



Lecture 1 - The Whole and Its PartsLecture 2 - Understanding Brainâ��s Shape - Segment 1 - Brain size and intelligenceLecture 3 - Understanding Brainâ��s Shape - Segment 2 - Save Wire PrincipleLecture 4 - Understanding Brainâ��s Shape - Segment 3 - Brain EvolutionLecture 5 - Neurons and Neural SignalingLecture 6 - Neural SignallingLecture 7 - Networks that Learn - Segment 1Lecture 8 - Multilayer Perceptrons Applications in Psychology and NeuroscienceLecture 9 - Organization of the Central Nervous System-Segment 1 - CortexLecture 10 - Organization of the Central Nervous System-Segment 2 - Subcortical StructuresLecture 11 - Maps in the Brain - Segment 1Lecture 12 - Maps in the Brain - Segment 2Lecture 13 - Emotions in the Brain - Segment 1Lecture 14 - Emotions in the Brain - Segment 2Lecture 15 - Memories and Holograms - Segment 1Lecture 16 - Memories and Holograms - Segment 2Lecture 17 - Consciousness - Segment 1Lecture 18 - Consciousness - Segment 2



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NPTEL Video Course - Biotechnology - NOC:Computational Systems Biology

Subject Co-ordinator - Prof. Karthik Raman



Lecture 1 - IntroductionLecture 2 - Introduction to ModellingLecture 3 - Introduction to ModellingLecture 4 - Fundamentals of Mathematical ModellingLecture 5 - Fundamentals of Mathematical ModellingLecture 6 - Fundamentals of Mathematical ModellingLecture 7 - Some Example ModelsLecture 8 - Representation of Biological NetworksLecture 9 - LabLecture 10 - LabLecture 11 - LabLecture 12 - LabLecture 13 - Introduction to NetworksLecture 14 - Introduction to NetworksLecture 15 - Introduction to Network BiologyLecture 16 - Introduction to Network BiologyLecture 17 - Introduction to Network BiologyLecture 18 - Network BiologyLecture 19 - Network ModelsLecture 20 - Network ModelsLecture 21 - Biological NetworksLecture 22 - Network PerturbationsLecture 23 - Community DetectionLecture 24 - Network MotifsLecture 25 - LabLecture 26 - LabLecture 27 - LabLecture 28 - Network BiologyLecture 29 - Lab



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Lecture 30 - LabLecture 31 - Reconstruction of Gene Regulatory NetworksLecture 32 - Reconstruction of Protein NetworksLecture 33 - Reconstruction of Signalling NetworksLecture 34 - Reconstruction of Signalling NetworksLecture 35 - Introduction to Dynamic ModellingLecture 36 - Introduction to Dynamic ModellingLecture 37 - Introduction to Dynamic ModellingLecture 38 - LabLecture 39 - LabLecture 40 - Parameter EstimationLecture 41 - Parameter EstimationLecture 42 - Parameter EstimationLecture 43 - Methods for Parameter EstimationLecture 44 - Direct Search MethodsLecture 45 - Genetic AlgorithmsLecture 46 - Genetic AlgorithmsLecture 47 - Other Evolutionary AlgorithmsLecture 48 - PyGMOLecture 49 - Dynamic Modelling RecapLecture 50 - LabLecture 51 - Guest LectureLecture 52 - Guest LectureLecture 53 - Guest LectureLecture 54 - Guest LectureLecture 55 - Guest LectureLecture 56 - Constraint-based Modelling of Metabolic NetworksLecture 57 - Flux Balance AnalysisLecture 58 - Flux Balance AnalysisLecture 59 - Flux Balance AnalysisLecture 60 - Other Constraint-Based ApproachesLecture 61 - Other Constraint-Based ApproachesLecture 62 - LabLecture 63 - Perturbations to Metabolic NetworksLecture 64 - LabLecture 65 - Understanding FBALecture 66 - Understanding FBALecture 67 - Perturbations to Metabolic NetworksLecture 68 - Perturbations to Metabolic Networks



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Lecture 69 - Perturbations to Metabolic NetworksLecture 70 - Constraint-based Modelling of Metabolic NetworksLecture 71 - LabLecture 72 - Integrating Regulatory Information into Constraint-Based ModelsLecture 73 - Elementary ModesLecture 74 - Elementary ModesLecture 75 - Constraint-based Modelling of Metabolic NetworksLecture 76 - Constraint-based Modelling of Metabolic NetworksLecture 77 - Constraint-based Modelling of Metabolic NetworksLecture 78 - LabLecture 79 - Constraint-based Modelling of Metabolic NetworksLecture 80 - Constraint-based Modelling of Metabolic NetworksLecture 81 - Constraint-based Modelling of Metabolic NetworksLecture 82 - $^{13}$C-Metabolic Flux Analysis using Mass SpectrometryLecture 83 - $^{13}$C-Metabolic Flux Analysis using Mass SpectrometryLecture 84 - $^{13}$C-Metabolic Flux Analysis using Mass SpectrometryLecture 85 - LabLecture 86 - Modelling Gene Regulatory NetworksLecture 87 - Modelling Gene Regulatory NetworksLecture 88 - Modelling Gene Regulatory NetworksLecture 89 - LabLecture 90 - LabLecture 91 - Computational Modelling of Host-Pathogen InteractionsLecture 92 - Computational Modelling of Host-Pathogen InteractionsLecture 93 - Robustness in Biological SystemsLecture 94 - Robustness in Biological SystemsLecture 95 - Robustness in Biological SystemsLecture 96 - Robustness in Biological SystemsLecture 97 - Obustness and EvolvabilityLecture 98 - obustness and EvolvabilityLecture 99 - Introduction to Synthetic BiologyLecture 100 - Advanced TopicsLecture 101 - Advanced TopicsLecture 102 - Advanced TopicsLecture 103 - Course Recap



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NPTEL Video Course - Biotechnology - NOC:Material and Energy Balances

Subject Co-ordinator - Prof.Vignesh Muthuvijayan



Lecture 1 - Fundamentals of Engineering CalculationsLecture 2 - Process Parameters and VariablesLecture 3 - Fundamentals of Material BalancesLecture 4 - Material Balance Calculations for Single Units Without Reactions - Part 1Lecture 5 - Material Balance Calculations for Single Units Without Reactions - Part 2Lecture 6 - Material Balance Calculations for Single Units Without Reactions - Part 3Lecture 7 - Material Balance Calculations for Single Units Without Reactions - Part 4Lecture 8 - Material Balance Calculations for Multiple Units Without Reactions - Part 1Lecture 9 - Material Balance Calculations for Multiple Units Without Reactions - Part 2Lecture 10 - Fundamentals of Reactive ProcessesLecture 11 - Material Balance Calculations For Single Units With A Single ReactionLecture 12 - Material Balance Calculations for Single Units with A Single Reaction (Continued...)Lecture 13 - Material Balance Calculations for Single Units with Multiple Reactions - Part 1Lecture 14 - Material Balance Calculations for Single Units with Multiple Reactions - Part 2Lecture 15 - Material Balance Calculations for Single Units with Multiple Reactions - Part 3Lecture 16 - Material Balance Calculations for Multiple Units with Reactions - Part 1Lecture 17 - Material Balance Calculations for Multiple Units with Reactions - Part 2Lecture 18 - Material Balances on Reactive Processes - TutorialsLecture 19 - Combustion ReactionsLecture 20 - Material Balances for Combustion ReactionsLecture 21 - Biochemical ReactionsLecture 22 - Biochemical ReactionsLecture 23 - Recycle Without ReactionsLecture 24 - Recycle with ReactionsLecture 25 - RecycleLecture 26 - BypassLecture 27 - PurgeLecture 28 - Material BalanceLecture 29 - Material Balance



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Lecture 30 - Material BalanceLecture 31 - The Unreasonable Effectiveness of Material BalanceLecture 32 - Constraint-based modellingLecture 33 - Flux balance analysis - Part 1Lecture 34 - Flux balance analysis - Part 2Lecture 35 - Energy Balance Terminologies and ConceptsLecture 36 - Introduction to Energy Balances - Part 1Lecture 37 - Introduction to Energy Balances - Part 2Lecture 38 - Introduction to Energy BalancesLecture 39 - Mechanical Energy BalancesLecture 40 - Mechanical Energy BalancesLecture 41 - Energy Balance Objectives and ProceduresLecture 42 - Introduction to Nonreactive Processes Without Phase ChangeLecture 43 - Energy Balances on Single-Phase Nonreactive ProcessesLecture 44 - Energy Balances on Single-Phase Nonreactive ProcessesLecture 45 - Fundamentals of Nonreactive Phase Change ProcessesLecture 46 - Estimating Latent HeatsLecture 47 - Energy Balances on Nonreactive Processes With Phase ChangeLecture 48 - Energy Balances on Nonreactive Processes With Phase ChangeLecture 49 - Energy Balances on Nonreactive Processes With Phase ChangeLecture 50 - Psychrometric ChartsLecture 51 - Energy Balances Using Psychrometric ChartsLecture 52 - Mixing and SolutionLecture 53 - Mixing and SolutionLecture 54 - Mixing and SolutionLecture 55 - Fundamentals for Energy Balances on Reactive Processes - Part 1Lecture 56 - Fundamentals for Energy Balances on Reactive Processes - Part 1 and Part 2Lecture 57 - Fundamentals for Energy Balances on Reactive Processes - TutorialsLecture 58 - Energy Balances on Reactive Processes - Part 1Lecture 59 - Energy Balances on Reactive Processes - Part 2Lecture 60 - Energy Balances on Reactive Processes - Part 3Lecture 61 - Energy Balances on Reactive Processes - Part 4Lecture 62 - Energy Balances on Reactive Processes - Part 5Lecture 63 - Energy Balances on Reactive Processes - Part 6Lecture 64 - Energy BalancesLecture 65 - Energy BalancesLecture 66 - Energy BalancesLecture 67 - Energy BalancesLecture 68 - Unsteady State Material Balances



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Lecture 69 - Unsteady State Energy Balances



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NPTEL Video Course - Biotechnology - NOC:Computer Aided Drug Design




Lecture 1 - IntroductionLecture 2 - Drug Discovery - IssuesLecture 3 - Target and Lead IdentificationLecture 4 - Drug And Data basesLecture 5 - Drug PropertiesLecture 6 - Drug - Properties / SMILESLecture 7 - Drug SolubilityLecture 8 - Drug Solubility / permeabilityLecture 9 - ADMELecture 10 - Drug - ADMELecture 11 - Drug - ADMELecture 12 - Drug - BBBLecture 13 - Pgp efflux/Drug LikenessLecture 14 - Drug LikenessLecture 15 - Molecular ModellingLecture 16 - Molecular Mechanics / Force FieldLecture 17 - Molecular Mechanics / Force FieldLecture 18 - Molecular Mechanics / Force FieldLecture 19 - Molecular Mechanics / Force FieldLecture 20 - ODES and Numerical methodsLecture 21 - ODES and Numerical methodsLecture 22 - Conformational Search / MDLecture 23 - Quantum MechanicsLecture 24 - Quantum MechanicsLecture 25 - Quantitative Struture Activity Relationship (QSAR)Lecture 26 - Quantitative Struture Activity Relationship (QSAR)Lecture 27 - Quantitative Struture Activity Relationship (QSAR)Lecture 28 - Quantitative Struture Activity Relationship (QSAR)Lecture 29 - Quantitative Struture Activity Relationship (QSAR)



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Lecture 30 - Quantitative Struture Activity Relationship (QSAR)Lecture 31 - 3D QSARLecture 32 - Pharmacophore modellingLecture 33 - Target based drug designLecture 34 - Target based drug designLecture 35 - Target based drug designLecture 36 - Target based drug designLecture 37 - DockingLecture 38 - DockingLecture 39 - Pharmacokinetics / pharmacodynamicsLecture 40 - Pharmacokinetics / pharmacodynamics



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NPTEL Video Course - Biotechnology - NOC:Plant Cell Bioprocessing

Subject Co-ordinator - Prof. Smita Srivastava



Lecture 1 - Introduction to plant cell technologyLecture 2 - History of plant cell and tissue cultureLecture 3 - Anatomy of plant cellsLecture 4 - Plant tissues and functionsLecture 5 - Photosynthesis and PhotorespirationLecture 6 - In-vitro culture initiationLecture 7 - Nutritional requirements of plant cellsLecture 8 - Organogenesis and RegenerationLecture 9 - Somaclonal variation and MicropropagationLecture 10 - Somatic embryogenesis and Protoplast cultureLecture 11 - Synthetic seeds, Cryopreservation and Freezing methodsLecture 12 - Secondary metabolism in plant cells - Part 1Lecture 13 - Secondary metabolism in plant cells - Part 2Lecture 14 - Secondary metabolism in plant cells - Part 3Lecture 15 - Secondary metabolism in plant cells - Part 4Lecture 16 - Optimization strategies - Part 1Lecture 17 - Optimization strategies - Part 2Lecture 18 - Optimization strategies - Part 3Lecture 19 - Optimization strategies - Part 4Lecture 20 - Biotransformation in plant culturesLecture 21 - Immobilization of plant cellsLecture 22 - Genetic transformations in plant cells - Part 1Lecture 23 - Genetic transformations in plant cells - Part 2Lecture 24 - Genetic transformations in plant cells - Part 3Lecture 25 - Plant Cell Bioreactors - Part 1Lecture 26 - Plant Cell Bioreactors - Part 2Lecture 27 - Bioreactors for Hairy Root culturesLecture 28 - Case study - Part 1Lecture 29 - Case study - Part 2



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NPTEL Video Course - Biotechnology - NOC:Tissue Engineering

Subject Co-ordinator - Prof.Vignesh Muthuvijayan



Lecture 1 - Introduction to Tissue Engineering - Part 1Lecture 2 - Introduction to Tissue Engineering - Part 2Lecture 3 - Introduction to Tissue Engineering - Part 3Lecture 4 - ScaffoldsLecture 5 - ScaffoldsLecture 6 - ScaffoldsLecture 7 - Hydrogels - Part 1Lecture 8 - Hydrogels - Part 2Lecture 9 - BioceramicsLecture 10 - Scaffold fabrication strategiesLecture 11 - Self AssemblyLecture 12 - 3D BioprintingLecture 13 - Material Characterization - Part 1Lecture 14 - Material Characterization - Part 2Lecture 15 - Material Characterization - Part 3Lecture 16 - Cell SourceLecture 17 - Cell Isolation - Part 1Lecture 18 - Cell Isolation - Part 2Lecture 19 - Tissue DynamicsLecture 20 - Cell DifferentiationLecture 21 - Cell AdhesionLecture 22 - Cell MigrationLecture 23 - Signaling and biomolecule delivery in Tissue EngineeringLecture 24 - Bioreactors in Tissue EngineeringLecture 25 - Challenges in Tissue EngineeringLecture 26 - Host integration and immune responses - Part 1Lecture 27 - Host integration and immune responses - Part 2Lecture 28 - Bioethics of Tissue Engineering - Part 1Lecture 29 - Bioethics of Tissue Engineering - Part 2



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Lecture 30 - Skin Tissue Engineering - Part 1Lecture 31 - Skin Tissue Engineering - Part 2Lecture 32 - Bone Tissue Engineering - Part 1Lecture 33 - Bone Tissue Engineering - Part 2Lecture 34 - Bone Tissue Engineering - Part 3Lecture 35 - Vascular Tissue EngineeringLecture 36 - Corneal Tissue Engineering - Part 1Lecture 37 - Corneal Tissue Engineering - Part 2



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NPTEL Video Course - Biotechnology - NOC:Thermodynamics for Biological Systems: Classical and Statistical Aspect

Subject Co-ordinator - Prof. G.K. Suraishkumar, Prof. Sanjib Senapati



Lecture 1 - Introduction and reviewLecture 2 - Review (Continued...)Lecture 3 - Need for analysisLecture 4 - Additional Thermodynamic FunctionsLecture 5 - State and Path VariablesLecture 6 - Equations for a Closed SystemLecture 7 - Chemical PotentialLecture 8 - Gibbs Duhem equationLecture 9 - Maxwellâ��s relationsLecture 10 - Inter-relationships between thermodynamic variables (Continued...)Lecture 11 - Some useful mathematical manipulationsLecture 12 - Thermodynamic relations for a closed system with 1 mole of pure substanceLecture 13 - Maximum workLecture 14 - Open systemsLecture 15 - Equations of state - Virial equationsLecture 16 - Equations of state - Cubic equationsLecture 17 - Volume estimationLecture 18 - Volume estimation (Continued...)Lecture 19 - Generalized correlationsLecture 20 - Generalized correlations (Continued...)Lecture 21 - Residual propertiesLecture 22 - Residual properties (Continued...)Lecture 23 - Generalized correlations and residual propertiesLecture 24 - Fugacity coefficient estimationLecture 25 - Review of module 3Lecture 26 - Learning aspectsLecture 27 - Chemical potential formulationsLecture 28 - Lewis and Randall ruleLecture 29 - Partial molar properties



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Lecture 30 - Partial molar property estimation from mixing experimentsLecture 31 - Partial molar property estimation (Continued...)Lecture 32 - Activity coefficient from excess propertyLecture 33 - Activity coefficient from excess property (Continued...)Lecture 34 - Models for activity coefficient in a binary systemLecture 35 - Models for activity coefficient for a binary system (Continued...)Lecture 36 - Review of module 4Lecture 37 - Criteria for phase equilibriumLecture 38 - Phase rule for non-reacting systemsLecture 39 - Clausius Clayperon equationLecture 40 - Clausius Clayperon equation (Continued...)Lecture 41 - Vapour liquid equilibriumLecture 42 - Vapour liquid equilibrium (Continued...)Lecture 43 - Estimation of fugacity coefficient from P-V-T data at equilibriumLecture 44 - Liquid-liquid and solid-liquid equilibriaLecture 45 - Review of module 5Lecture 46 - Criteria for bioreaction equilibriaLecture 47 - Phase rule for reacting biosystemsLecture 48 - Equilibrium constantsLecture 49 - Effect of temperature on the equilibrium constantsLecture 50 - Reaction in liquid or solid phasesLecture 51 - Free energy changes for some bioreactionsLecture 52 - ElectrolytesLecture 53 - Review of the classical thermodynamics partLecture 54 - Introduction to Statistical thermodynamicsLecture 55 - Concepts of macro and microstatesLecture 56 - Thermodynamic probabilityLecture 57 - Boltzmann distribution lawLecture 58 - Defining Î² in Boltzmann distribution lawLecture 59 - Relationship between partition function and thermodynamic quantitiesLecture 60 - Partition function of mono atomic gasesLecture 61 - Entropy in terms of probablityLecture 62 - Gibbs paradoxLecture 63 - Thermodynamic probability for distinguishable particlesLecture 64 - Thermodynamic probability for indistinguishable particlesLecture 65 - Sackur - Tetrode equationLecture 66 - Partition function and Helmholtz and Gibbs free energyLecture 67 - Ensemble approachLecture 68 - Ensemble average, time average, Ergodic hypothesis



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Lecture 69 - Partition function for classical systemsLecture 70 - Pair potentials for atomic systemsLecture 71 - Potential for molecular systemsLecture 72 - Computer code for LJ potentialLecture 73 - Introduction to computer simulationsLecture 74 - Computer simulations of macromoleculesLecture 75 - MD simulation examplesLecture 76 - Link between theory and experimentsLecture 77 - MD protocolLecture 78 - Computer simulation tricksLecture 79 - Understanding force fieldsLecture 80 - Idea of Z-matrixLecture 81 - Basics of MD simulationsLecture 82 - Integration algorithmsLecture 83 - Calculation of Columbic forceLecture 84 - Calculation of LJ forceLecture 85 - Monte Carlo simulationsLecture 86 - Analysis of MD trajectoryLecture 87 - Case study (water)



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NPTEL Video Course - Biotechnology - Analytical Technologies in Biotechnology

Subject Co-ordinator - Dr. Ashwani K. Sharma

Co-ordinating Institute - IIT - Roorkee


Lecture 1 - Basic concepts in microscopy - 1Lecture 2 - Basic concepts in microscopy - 2Lecture 3 - Dark-field and phase contrast microscopyLecture 4 - Differential interference contrast and polarizationLecture 5 - Fluorescence and confocal microscopyLecture 6 - Transmission electron microscopyLecture 7 - Transmission electron microscopy cont. and scanning electron microscopyLecture 8 - Basic concepts - 1Lecture 9 - Basic concepts - 2Lecture 10 - GM counting and Scintillation countingLecture 11 - Scintillation counting continuedLecture 12 - Autoradiography and RIALecture 13 - Safety aspects and applicationsLecture 14 - Introduction and Basic concepts in chromatography - 1Lecture 15 - Basic concepts in chromatography - 2Lecture 16 - Low-pressure liquid chromatography (LPLC) and high performance liquid chromatography (HPLC)Lecture 17 - Ion-exchange chromatographyLecture 18 - Gel-filtration chromatographyLecture 19 - Affinity chromatographyLecture 20 - Gas-liquid chromatographyLecture 21 - Basic concepts in electrophoresisLecture 22 - Horizontal and vertical gel electrophoresisLecture 23 - Native gel electrophoresis and SDS-PAGELecture 24 - Isoelectric focusing (IEF), 2-D gel electrophoresis and protein detection methodsLecture 25 - Electrophoresis of nucleic acidsLecture 26 - Immunoelectrophoresis and capillary electrophoresisLecture 27 - Introduction and Basic Concepts - 1Lecture 28 - Basic concepts - 2Lecture 29 - Types of centrifuges and analytical ultracentrifugation method



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Lecture 30 - Separation methods in preparative ultracentrifugesLecture 31 - Types of rotorsLecture 32 - Types of rotors cont. and care of rotorsLecture 33 - Introduction and basic conceptsLecture 34 - UV-Visible spectroscopyLecture 35 - Infrared and fluorescence spectroscopyLecture 36 - Circular dichroism (CD) spectroscopyLecture 37 - Nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallographyLecture 38 - Atomic spectroscopy and mass spectrometryLecture 39 - Polymerase chain reaction(PCR)Lecture 40 - DNA sequencing methodsLecture 41 - Enzyme linked immunosorbent assay (ELISA)



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NPTEL Video Course - Biotechnology - NOC:Biomedical Nanotechnology

Subject Co-ordinator - Prof. P.Gopinath



Lecture 1 - Introduction to NanoLecture 2 - Nano-BiomimicryLecture 3 - Synthesis of nanomaterials by Physical and Chemical MethodsLecture 4 - Synthesis of nanomaterials by Biological MethodsLecture 5 - Characterisation of NanomaterialsLecture 6 - DNA NanotechnologyLecture 7 - Protein and Glyco NanotechnologyLecture 8 - Lipid NanotechnologyLecture 9 - Bio-NanomachinesLecture 10 - Carbon nanotubes and Its Bio-ApplicationsLecture 11 - Nanomaterials for Cancer DiagnosisLecture 12 - Nanomaterials for Cancer therapyLecture 13 - Nanotechnology in Tissue EngineeringLecture 14 - Nano artificial cellsLecture 15 - Nanotechnology in Organ PrintingLecture 16 - Nanotechnology in Point-of-Care DiagnosticsLecture 17 - Nano-Pharmacology and Drug TargetingLecture 18 - Cellular uptake mechanisms of nanomaterialsLecture 19 - In vitro Methods to study antibacterial and anticancer properties of nanomaterialsLecture 20 - Nanotoxicology



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NPTEL Video Course - Biotechnology - NOC:Plant Developmental Biology

Subject Co-ordinator - Prof. Shri Ram Yadav



Lecture 1 - Life Cycle of an AngiospermLecture 2 - Characteristics of Plant Growth and Development - ILecture 3 - Characteristics of Plant Growth and Development - IILecture 4 - Molecular Genetics of Plant Development - ILecture 5 - Molecular Genetics of Plant Development - IILecture 6 - Molecular Genetics of Plant Development - IIILecture 7 - Molecular Genetics of Plant Development - IVLecture 8 - Molecular Genetics of Plant Development (Continued...) - ILecture 9 - Molecular Genetics of Plant Development (Continued...) - IILecture 10 - Molecular Genetics of Plant Development (Continued...) - IIILecture 11 - Root DevelopmentLecture 12 - Root Development (Continued...)Lecture 13 - Root Development (Vascular Development)Lecture 14 - Root BranchingLecture 15 - Shoot DevelopmentLecture 16 - Shoot DevelopmentLecture 17 - Shoot DevelopmentLecture 18 - Shoot DevelopmentLecture 19 - Cell-Cell Communication During Plant DevelopmentLecture 20 - Techniques Used in Lab



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NPTEL Video Course - Biotechnology - NOC:Learning about Learning: A Course on Neurobiology of Learning and Memory

Subject Co-ordinator - Prof. Balaji Jayaprakash

Co-ordinating Institute - IISc - Bangalore


Lecture 1 - Introduction to Learning and Memory - ILecture 2 - Introduction to Learning and Memory - IILecture 3 - Associative Learning ILecture 4 - Associative learning IILecture 5 - Introduction to the Rescorla Wagner ModelLecture 6 - Application of Rescorla Wagner Model - ILecture 7 - Application of Rescorla Wagner Model - IILecture 8 - Application of Rescorla Wagner Model - IIILecture 9 - Application of Rescorla Wagner Model - IVLecture 10 - Limitations of Rescorla Wagner ModelLecture 11 - Introduction of Reinforcement Learning - ILecture 12 - Introduction of Reinforcement Learning - IILecture 13 - Introduction of Reinforcement Learning - IIILecture 14 - Sign Tracking vs Goal Oriented/Tracking; Linking complex behaviors to simple moleculesLecture 15 - Sign Tracking vs Goal Oriented; Learning Linking complex behaviors to simple molecules - IILecture 16 - Memory in Molecular Terms - ILecture 17 - Memory in Molecular Terms - IILecture 18 - Memory in Molecular Terms - IIILecture 19 - Memory in Molecular Terms - IVLecture 20 - Memory in Molecular Terms - V



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NPTEL Video Course - Biotechnology - NOC:Drug Delivery: Principles and Engineering

Subject Co-ordinator - Rachit Agarwal



Lecture 1 - Drug Delivery Introduction and PharmacokineticsLecture 2 - Pharmacokinetics (Continued...)Lecture 3 - Pro-drugs and Polymers IntroductionLecture 4 - Polymers - SynthesisLecture 5 - Polymers - PropertiesLecture 6 - Biomedical PolymersLecture 7 - Biodegradable Polymers and Polymer Drug Conjugates - ILecture 8 - Polymer Drug Conjugates - IILecture 9 - Research Paper Discussion and Diffusion Controlled SystemsLecture 10 - Controlled ReleaseLecture 11 - Controlled ReleaseLecture 12 - Controlled ReleaseLecture 13 - Math ExerciseLecture 14 - Hydrogels - ILecture 15 - Hydrogels - IILecture 16 - Hydrogels - IIILecture 17 - Hydrogels - IVLecture 18 - Nano and Micro-particles - ILecture 19 - Nano and Micro-particles - IILecture 20 - Nano and Micro-particles - IIILecture 21 - Nano and Micro-particles - IVLecture 22 - Nano and Micro-particles - VLecture 23 - Nano and Micro-particles - VILecture 24 - Nano and Micro-particles - VIILecture 25 - Protein Adsorption - ILecture 26 - Protein Adsorption - IILecture 27 - Protein Adsorption - IIILecture 28 - Tissue Engineering - ILecture 29 - Tissue Engineering - II



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Lecture 30 - Tissue Engineering - IIILecture 31 - Drug Delivery in Tissue Engineering - ILecture 32 - Drug Delivery in Tissue Engineering - IILecture 33 - Implant Associated Infections - ILecture 34 - Implant Associated Infections - IILecture 35 - Route Specific DeliveryLecture 36 - Route Specific DeliveryLecture 37 - Route Specific DeliveryLecture 38 - Route Specific DeliveryLecture 39 - Route Specific DeliveryLecture 40 - Route Specific DeliveryLecture 41 - Route Specific DeliveryLecture 42 - Research Paper DiscussionLecture 43 - Route Specific DeliveryLecture 44 - Intravenous AdministrationLecture 45 - Immune System - IILecture 46 - Complement System and Blood ClottingLecture 47 - Blood Clotting and Hemocompatibility of Materials; Adaptive Immune ResponseLecture 48 - Adaptive Immune Response and VaccineLecture 49 - VaccinesLecture 50 - Vaccines and Immuno-isolated Cell TherapyLecture 51 - Immuno-isolated Cell TherapyLecture 52 - Immuno-isolated Cell and Gene TherapyLecture 53 - Gene DeliveryLecture 54 - Gene DeliveryLecture 55 - Genes as VaccinesLecture 56 - VaccinesLecture 57 - Cancer VaccinesLecture 58 - Cancer VaccineLecture 59 - Responsive Delivery Systems - ILecture 60 - Responsive Delivery Systems - IILecture 61 - Targeted Drug Delivery SystemLecture 62 - Targeted Drug Delivery SystemLecture 63 - Nanotoxicology and Translation Pathways



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NPTEL Video Course - Biotechnology - NOC:Fundamentals of Micro and Nanofabrication

Subject Co-ordinator - Prof. Shankar Selvaraja



Lecture 1 - IntroductionLecture 2 - SubstrateLecture 3 - Substrate (Continued...)Lecture 4 - Introduction to cleanroomLecture 5 - Contamination and surface cleaningLecture 6 - Advanced cleaning techniquesLecture 7 - DefectsLecture 8 - DiffusionLecture 9 - Diffusion - Advanced ConceptsLecture 10 - Ion ImplantationLecture 11 - Ion Implantation (Continued...)Lecture 12 - Native FilmsLecture 13 - Native FilmsLecture 14 - Native FilmsLecture 15 - Methods and Some DefinitionsLecture 16 - Chemical Vapor DepostionLecture 17 - Chemical Vapor DepostionLecture 18 - Chemical Vapor DepostionLecture 19 - Chemical Vapor DepostionLecture 20 - Chemical Vapor DepostionLecture 21 - Atomic Layer DepostionLecture 22 - Atomic Layer Depostion (Continued...)Lecture 23 - Physical Vapor DepositionLecture 24 - Physical Vapor DepositionLecture 25 - Physical Vapor DepositionLecture 26 - MettalizationLecture 27 - MettalizationLecture 28 - Pattern Transfer BascisLecture 29 - Optical lithography basics



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Lecture 30 - Optical lithography basicsLecture 31 - Optical LithographyLecture 32 - Optical LithographyLecture 33 - Projection LithographyLecture 34 - Projection LithographyLecture 35 - Optical lithographyLecture 36 - Optical LithographyLecture 37 - Lithography process technology glossaryLecture 38 - Optical LithographyLecture 39 - Electron beam lithographyLecture 40 - Electron beam lithographyLecture 41 - Emerging lithography techniquesLecture 42 - Etching Figures of MeritLecture 43 - Wet etching BasicsLecture 44 - Wet Ething RecipesLecture 45 - Wet Ething RecipesLecture 46 - Dry etchLecture 47 - Dry etchLecture 48 - Dry etchLecture 49 - Dry etchLecture 50 - Dry etchLecture 51 - Chemical Mechanical Polishing (CMP)Lecture 52 - Chemical Mechanical Polishing (CMP)Lecture 53 - Design for Manufacturability - 1Lecture 54 - Design for Manufacturability - 2Lecture 55 - Design for ManufacturabilityLecture 56 - Process integrationLecture 57 - PV integrationLecture 58 - CMOS integrationLecture 59 - Lab demoLecture 60 - Lab demoLecture 61 - CMOS process for photonics application



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NPTEL Video Course - Biotechnology - NOC:Optical Spectroscopy and Microscopy: Fundamentals of Optical Measurements and Instrumentation

Subject Co-ordinator - Prof. Balaji Jayaprakash



Lecture 1 - Optical Focus and Localisation of LightLecture 2 - Relating Photon's Momentum to Spot SizeLecture 3 - Shortest Pulse of LightLecture 4 - Behaviour of light through polarizersLecture 5 - Nature of LightLecture 6 - Revisiting Polarisation Through Ket VectorsLecture 7 - Light through PolarisersLecture 8 - Light through PolarisersLecture 9 - Time Dependent Perturbation Theory (TDPT)Lecture 10 - TDPT in Steps-1Lecture 11 - TDPT in Steps-2Lecture 12 - TDPT in Steps-3Lecture 13 - Fermi's Golden RuleLecture 14 - Beer Lambert's Law from TDPTLecture 15 - Einstein's PhenomenologyLecture 16 - Einstein's Coefficients, Fluorescence and LifetimeLecture 17 - Fock States and Photonic Treatment of Light Lecture 18 - Operators in Fock State SpaceLecture 19 - Light Matter Interaction and Rudimentary Feynman DiagramsLecture 20 - Emergence of Spontaneous and Stimulated Emission ProcessesLecture 21 - Lecture 21Lecture 22 - Lecture 22Lecture 23 - Lecture 23Lecture 24 - Lecture 24Lecture 25 - Lecture 25Lecture 26 - Introduction to LASERLecture 27 - LASER population dynamicsLecture 28 - LASER population dynamics - Part- 2Lecture 29 - Real world LASER and characteristics of LASER emission



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Lecture 30 - Temporal and Spatial CoherenceLecture 31 - Transverse and Longitudinal modes of LASERLecture 32 - Pulsed LASERLecture 33 - Q-switching in detailLecture 34 - Q-switching in detail - Part 2Lecture 35 - Basics of mode lockingLecture 36 - Basics of mode locking - Part 2Lecture 37 - Pulse compressionLecture 38 - Real world system (Mode lock Part-2)Lecture 39 - TEM modeLecture 40 - Alignment basicsLecture 41 - Non-Linear OpticsLecture 42 - Confocal DetectionLecture 43 - Interference FiltersLecture 44 - Laser Scanning System - 1Lecture 45 - Laser Scanning System - 2Lecture 46 - Alignment of Moving BeamsLecture 47 - Decoding an Objective Lens - 1Lecture 48 - Decoding an Objective Lens - 2Lecture 49 - Designing Lens SystemsLecture 50 - Astigmatism and Field CurvatureLecture 51 - Intro to Lab SessionLecture 52 - Optics in LABLecture 53 - Optics in LabLecture 54 - Kinematic MountsLecture 55 - Alignment with out irisLecture 56 - Fluorescecne Spectrometer - 1Lecture 57 - Fluorescecne Spectrometer - 2Lecture 58 - Ti



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