Nucleoside 5’-

Nucleotide

Adenine

2’-deoxyadenosine

2’-

Ribonucleoside

Deoxyribonucleoside

Four bases in DNA

dAMP, dGMP, dCMP, dTMP

5’

3’

= pApCpG

T A

C G

A:T and G:C base pairs are very similar.

Hyperchromism = more

color

AT-rich region melts first.

dNTP

3’

dNTP

DNA polymerase is a proof-reading enzyme.

Mg2+

3’

RNA

HIV-1 is a retrovirus.

Reverse transcriptase

integrase