©2014 Waters Corporation 1
NuGenesis Lab Management System
©2014 Waters Corporation 2
The Changing Face of Industry
What we were hearing from customers:- – ‘The analysis is essential, but being able to manage the data is the
problem’
– ‘How to rationalize and centralize their business information systems?’
– ‘I need workflow and sample management capabilities but I don’t
require a full featured LIMS’ – ‘Manage tests and follow protocols with flexibility of working in both
structured and unstructured workflows’
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Challenges in the Industry
Revenue at Stake • Patent Cliff • Competitive Solutions • Product Pipeline
Cost Control • Streamline
Development • Globalize Operations • Simplify Processes
Optimize Use of Assets • Standardisation • Flexible Use of
Employees • Outsourcing
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Challenges at Lab and IT level
Simplify Lab Processes •Remove Non-Value Added
Steps •Right First Time •Flexible and Manageable
Standardization •Global Applications •Compliance •Easy Integration
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Current Solutions
DISCOVERY DEVELOPMENT QC
ERP
LIMS B
LES
SDMS
CDS
Instrument
LIMS A
ELN B
SDMS
CDS
Instrument
SDMS
MS Software
Instrument
ELN A
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Current solutions driving Business Systems into the lab often… Leave significant gaps Frustrate the users Are difficult to deploy
and support Don’t deliver the expected
Return on Investment
The Challenge
ERP
LIMS
ELN
SDMS
CDS
Instrument
Business Systems
Laboratory Systems
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Solution with NuGenesis LMS
DISCOVERY DEVELOPMENT QC
Business Systems
Instrument Instrument Instrument
Business Systems
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What is NuGenesis Lab Management System? NuGenesis LMS Data Management (SDMS)
o Bring together all the information from all instruments and analytical
techniques in a single database o Provide the tools to manage, repurpose, archive, protect and ensure
compliance in a single location
NuGenesis LMS Laboratory Notebook (ELN)
o Provide the tools to document experimental design and results, from free-form R&D environments to process-driven QA laboratories, in a single package
NuGenesis LMS Laboratory Management (LMS)
o Provide the tools to implement customised workflows, allowing data to
be taken from instruments and taken through the entire process to final disposal.
o Help eliminate the need for cumbersome, traditional mechanisms for workflow management
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NuGenesis Lab Management System
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Capturing and Cataloging Scientific Data
Sampling Analytical Data Acquisition
Data Processing Results
File Data Printed Results
NuGenesis SDMS Long Term Archive
E-signature Project Auto
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View Data Without Original Software
Gel Images
HPLC
Mass Spec NMR
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View Data With InSpector
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Data Management – Data Lifecycle
Data Retention can be Enabled on a Project
Flexible Retention Policies
Complete Manual or Automatic Deletion After Expiration
Legal Holds will Prevent Any Change or Deletion
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New Advanced Search
NuGenesis Lab Management System has a new search engine
Using Paradigm Scientific Search – Is a corporate scientific search – New and novel technology – Introduced 2013
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Integrated Paradigm™ Scientific Search
Search NuGenesis and Empower for the following:
Text/Key Words
Search-by-Document
Digital Image
Chemical Structure or Chemical Reaction
Analytical Dataset
Biological Content as Science Objects
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NuGenesis Lab Management System
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Major Types of Testing
Discovery, Investigative – Free-flow – Geared towards new
scientific discoveries – Seeks to protect
intellectual property rights
Process Driven, Investigative – Follows established methods – Geared towards repeat tasks – Often used to compare to
regulations e.g. DEFRA
Maze obtained from pbs.org
Test Test
?
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NuGenesis 8 Freeflow Lab Notebook
Introduction Experimental
Results
Conclusions
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Any Information Can Be Included
Text including tables, pictures etc. Images and drawings Chemical structures and reactions Analytical data such as spectra,
chromatograms, properties Biological data Reports Scans, movies ...
To a solution of dry methyl 1--D-ribofuranosyl-4,5-imidazoledicarbo xylate2 (2) (500 mg, 1.58 mmol) in dry pyridine (10 mL) was added 1,3-dichloro-1,1,3,3-
tetraisopropyldisiloxane7 (550 mg, 1.75 mmol), and the mixture was stirred for 4 h at ambient temperature with...
Analytical Data Yield 800 mg (91%) Rf 0.38 (chloroform/ methanol, 30:1)
O
O
O
NH3 NH
O
O
+
Acylation of Amines by Anhydrides: Amino-de-acyloxy-substitution
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Combine Procedure and Data Entry Using Electronic Forms
Procedure
Data Entry
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Simple Devices – Balance Integration
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Test Preparation and Specifications – Test Documentation
Transferred from ERP Scanned Bar Codes
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NuGenesis 8 - Workflow Management Defined Workflow & Easy Review
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Integrated Supporting Inventory
Supporting Document
Instrument Standards Reagents
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Inventories
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NuGenesis Lab Management System
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“My Work Portal” User Centric Access
Needs overview about the status of the work Assign tests to analysts Needs overview entire request context Review test documents Approve test requests
Find all pending tests that relevant for them Calibrate instruments Run and document the actual tests Check in/out samples Print sample labels
Lab Manager
Analyst
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NuGenesis 8 Sample Management (Requests)
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NuGenesis 8 Sample Management (Tests)
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NuGenesis 8 Sample Management (Samples)
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Review-By-Exception
Result correct?
Result not modified?
OOS?
Who is responsible?
Result signed?
Reagents fit-for-use?
Instruments fit-for-use?
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NuGenesis 8 available interfaces NuGenesis 8 SAP-QM interface Providing a bi-directional SAP certified interface to minimize transcription errors through automation of information transfer from SAP-QM NuGenesis 8 SDMS interface to ELN Support of external third party laboratories data and direct access to file and printed information within NuGenesis ELN and Sample Management Support of simple devices Direct interface to small laboratory devices such as balances and pH meters and LabX software NuGenesis 8 interface to Empower Create sample sets, access, review and process data within Empower data within NuGenesis
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NuGenesis Lab Management System
What’s New:
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Stability Workflow
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NuGenesis Lab Management System
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Integration with External Labs: Web Interface
Add samples one by one or import a list
Review status of all samples Quickly check for Notifications
Account settings
Top level view of the Dashboard
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NuGenesis Lab Management System
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Connecting the Laboratory to Business
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NuGenesis Lab Management System
LIMS Capabilities without the Complexities
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