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Starts with damage of a highly loaded part
Focal wear then painful symptoms
Pain and inactivity -- diet changes
Increasing weight -- increasing load
Inactivity weakens cartilage, bone, ligaments and muscles with more loss of support
Localized wear changes alignment and adds further to load and increasing damage.
Vicious cycle: increase load -> decrease use = more damage Vicious cycle: increase load -> decrease use = more damage
How Does Knee OA Progress?How Does Knee OA Progress?
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Speeds Up Inactivity
Excessive load
Weight gain
Delaying treatment
Slows Down Keeping mobile and strong
Modifying loading activity
Weight loss
Early treatment
Factors Affecting ProgressionFactors Affecting Progression
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Mild varus Mild varus Grade 2 damageGrade 2 damageJoint Replacement Joint Replacement not indicatednot indicated
Marked varus Marked varus Grade 8 damageGrade 8 damageJoint Replacement Joint Replacement indicatedindicated
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What the surgeon seesHealthy
ProgressionProgression