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139 OPHTHALMOLOGICAL SOCIETY. minent and alarming character due to disease in other organs; but such cases are quite different from this one in that here there were found a large number of tumours scattered through both motor and sensory regions, evidently of very considerable age and yet apparently without causing symptoms till within a day or two of death, and even these symptoms were induced apparently by meningeal affection and not by the tumours. It is also I coteworthy that the child’s condition had all along been quite favourable for the observation of any cerebral symptoms that might have been present, and he was constantly under observation, so that their occurrence could scarcely have been missed. The mesenteric condition and the ulceration of the bowels were also of considerable interest ; but so many cases of a somewhat similar nature are met with that I do not desire to dwell upon this aspect of the case. They pro- bably constitute the primary lesion. Medical Societies. OPHTHALMOLOGICAL SOCIETY. Epithelial Pearl Twmo1t’1’ in the Iris following Implantation of Eyelash in the Anterior Chamber.-The Diagnosis and P1’ognosis of Pathological Myopia.-Reaurrent Third Nerve Palsy associated with Migraine. AN ordinary meeting of the above Society was held on May, July 7th, the President, Mr. HENRY POWER, M.B., 1.R.C.S., in the chair. Mr. F. RICHARDSON CROSS and Mr. E. TREACHER COLLINS contributed a paper on Epithelial Pearl Tumour in the Iris following Implantation of Eyelash in the Anterior Chamber. A boy aged eight presented himself for loss of sight in the right eye, seven months after the eye had been wounded with a piece of wire. On examination the eye was free from in- flammation, tension was normal and there was traumatic - eapsular cataract, with posterior synechise. At the upper inner segment of the anterior chamber was a small nodule, from which an eyelash passed downwards in front of the iris. An operation was undertaken to remove the eyelash and, if possible, the small nodule, which was diagnosed to be an epithelial implantation cyst growing from the root-sheath of ’the cilium. The eyelash was readily removed, but the cyst was so closely adherent to the iris, and this so fixed by adhesions that it could not be extracted, but came away piece- meal in the forceps. The wound healed well. Two months .afterwards the tumour had commenced to grow again. The patient then disappeared for nearly a year, when he returned with great irritability, lacrymation, and photophobia of the right eye. The tumour had much increased in size, and as the left eye was sympathetically irritated, and the former operation had been so difficult, the eye was enucleated and sent .to Mr. Treacher Collins, who reported the tumour to be sur- rounded by pigmented iris tissue, and free from the cornea, vitreous and ciliary body. The mass situated in the iris was a ’cyst with opaque white contents lined by laminated epithe- lium, the cells in contact with the iris tissue being the best developed, the innermost ones being flat and scaly ; the con- tents of the cavity consisted of fat globules and polyhedral wells in which no nucleus was stained. They were probably epithelial cells undergoing degeneration. The ,papillary border of the iris was united by newly formed fibrous tissue to the anterior capsule of the lens. Seven analogous cases were quoted as showing that the histology of the tumours was similar and that all have resulted from a long residence of an eyelash in the anterior chamber. In contradistinction the successful result of early removal of eyelashes from the anterior chamber was men- tioned and the immediate diagnosis of such a condition and its prompt treatment insisted on.-Dr. ROCKLIFFE (Hull) mentioned a case he had reported to the Society in which a cystic tumour in the anterior chamber had followed the im- plantation of an eyelash. Since reporting that case he had met with another in which one or perhaps two lashes had been carried into the anterior chamber by a piece of wire penetrating the cornea.-Mr. ERNEST CLARKE referred to a ’case he had reported two years ago, in which he had been able to remove the eyelash.-Mr. SNELL (Sheffield) spoke of case now under observation in which he had operated for cataract fourteen years since. There was now a cyst in the anterior chamber which he thought might be of the same nature as that described. Dr. RAYNBH D. BATTEN read a paper on the Diagnosis and Prognosis of l’athological Myopia. After reference to a former paper in which lie maintained that myopia was frequently the result of constitutional disease,l he said that the object of the present communication was to show that a diagnosis of the constitutional cause of myopia may be made from the condition of the fundus. Physiological myopia should be confined to a simply refractive con- dition, in which there is no fundus change of any kind. Physiological myopia is not necessarily a refractive con- dition, and may even be associated with emmetropia or hypermetropia, and is characterised by the formation of crescents, the stretching and distortion of the vessels, the presence of staphylomata, and by local and general dis- turbance of pigment. At present physiological myopia is not distinguished from pathological myopia in its early stages, but only when the latter is far advanced. Pathological myopia may be acute, chronic, progressive or stationary. The acute may end in arrest or become chronic, and may be the result of various constitutional diseases. In the chronic form a diagnosis may be made between myopia due to cardio- vascular conditions, struma and inherited syphilis and un- healthy occupations. Pigmentary changes associated with ’myopia: Marked pigment change at the margin of the cres- cent is a sign of acute myopia, and in the chronic form a distinction is made between a thin choroid, rendering the choroidal vessels visible and occasionally associated with a very fine dust-like retinal pigment change and a choroid in which the pigment appears to be divided into islands ; the former is attributable to cardio-vascular conditions; the latter, to strumous or specific disease. f3taphylomata: Four classes : (1) That in which the staphyloma is in the macular region ; i (2) that in which it occurs on the nasal side; (3) that in which the optic dbc forms the deepest part of the staphyloma; and (4) that in which it takes place towards the periphery. In all cases except the first the refractive condition at the optical axis is no measure of the extent of the myopia. Peripheral myopia is a cause of astigmatism, by causing distortion of the lens and cornea. Distortion of the vessels : Three forms : (1) When the vessels are drawn from their normal course in relation to the optic disc ; (2) when they appear stretched and straightened ; (3) when they emerge by separate branches from the optic disc. The direction of the distortion of the vessels depends on the posi- tion of the staphyloma. This is particularly marked in cases of nasal staphyloma, the vessels being drawn to the nasal side of the optic disc and the macular branches having to bend back in order to supply that region. Distortion of the vessels is one of the early signs of commencing myopia. The direction of the distortion points to the position of the staphyloma and the degree of the distortion or stretching of the vessels is an important factor in the prognosis. Central (physiological) cupping of the optic discs is a form of the staphyloma and an early manifestation of commencing myopia and responsible for the exit of the vessels from the optic disc in numerous branches, the main trunk of the vessels having been drawn into the staphyloma. The early premonitory signs of myopia are central cupping, distortion of the vessels, commencing crescents and astigmatism. Mr. SNELL (Sheffield) related two cases of Recurrent Third Nerve Palsy associated with Migraine. One was in a young man aged twenty-seven. Migraine had existed since the age of ten, but only for the last seven years had the eye been closed with the attacks. The attacks occurred at first at in- tervals of about eight weeks, then at every two or three weeks, and lasted for three or four days. The palsy of the third nerve was practically complete ; ptosis and paralysis of the ocular muscles, together with dilated pupil and palsy of accommoda- tion. The attacks commenced with vomiting and headache. The ocular palsy in the interval did not completely pass off, and the latest accounts, two years after he had last been seen, indicated that the drooping of the lid was becoming more permanent. The second case was in a girl aged eighteen. She had two attacks at intervals of four years, though migraine outbreaks continued in the interval. Each time she had made a perfect recovery, though the third nerve was not, at the worst, as completely involved as in the first case. Recovery was much longer in taking place. Mr. Snell gave additional particulars of a similar case he had brought to the notice of the Society some years ago. He remarked 1 Ophthalmic Review, January, 1892.
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Page 1: OPHTHALMOLOGICAL SOCIETY

139OPHTHALMOLOGICAL SOCIETY.

minent and alarming character due to disease in other

organs; but such cases are quite different from thisone in that here there were found a large number oftumours scattered through both motor and sensory regions,evidently of very considerable age and yet apparentlywithout causing symptoms till within a day or two of

death, and even these symptoms were induced apparentlyby meningeal affection and not by the tumours. It is also I

coteworthy that the child’s condition had all along been quitefavourable for the observation of any cerebral symptoms thatmight have been present, and he was constantly underobservation, so that their occurrence could scarcely havebeen missed. The mesenteric condition and the ulcerationof the bowels were also of considerable interest ; but so manycases of a somewhat similar nature are met with that I donot desire to dwell upon this aspect of the case. They pro-bably constitute the primary lesion.

Medical Societies.OPHTHALMOLOGICAL SOCIETY.

Epithelial Pearl Twmo1t’1’ in the Iris following Implantationof Eyelash in the Anterior Chamber.-The Diagnosis andP1’ognosis of Pathological Myopia.-Reaurrent Third NervePalsy associated with Migraine.AN ordinary meeting of the above Society was held on

May, July 7th, the President, Mr. HENRY POWER, M.B.,1.R.C.S., in the chair.

Mr. F. RICHARDSON CROSS and Mr. E. TREACHER COLLINScontributed a paper on Epithelial Pearl Tumour in the Irisfollowing Implantation of Eyelash in the Anterior Chamber.A boy aged eight presented himself for loss of sight in theright eye, seven months after the eye had been wounded witha piece of wire. On examination the eye was free from in-flammation, tension was normal and there was traumatic

- eapsular cataract, with posterior synechise. At the upperinner segment of the anterior chamber was a small nodule,from which an eyelash passed downwards in front of the iris.An operation was undertaken to remove the eyelash and,if possible, the small nodule, which was diagnosed to be anepithelial implantation cyst growing from the root-sheath of’the cilium. The eyelash was readily removed, but the cystwas so closely adherent to the iris, and this so fixed byadhesions that it could not be extracted, but came away piece-meal in the forceps. The wound healed well. Two months.afterwards the tumour had commenced to grow again. The

patient then disappeared for nearly a year, when he returnedwith great irritability, lacrymation, and photophobia of theright eye. The tumour had much increased in size, and asthe left eye was sympathetically irritated, and the formeroperation had been so difficult, the eye was enucleated and sent.to Mr. Treacher Collins, who reported the tumour to be sur-rounded by pigmented iris tissue, and free from the cornea,vitreous and ciliary body. The mass situated in the iris was a’cyst with opaque white contents lined by laminated epithe-lium, the cells in contact with the iris tissue being the bestdeveloped, the innermost ones being flat and scaly ; the con-tents of the cavity consisted of fat globules and polyhedralwells in which no nucleus was stained. They were

probably epithelial cells undergoing degeneration. The

,papillary border of the iris was united by newly formedfibrous tissue to the anterior capsule of the lens.Seven analogous cases were quoted as showing that thehistology of the tumours was similar and that all haveresulted from a long residence of an eyelash in the anteriorchamber. In contradistinction the successful result of earlyremoval of eyelashes from the anterior chamber was men-tioned and the immediate diagnosis of such a condition andits prompt treatment insisted on.-Dr. ROCKLIFFE (Hull)mentioned a case he had reported to the Society in which acystic tumour in the anterior chamber had followed the im-plantation of an eyelash. Since reporting that case he hadmet with another in which one or perhaps two lashes hadbeen carried into the anterior chamber by a piece of wirepenetrating the cornea.-Mr. ERNEST CLARKE referred to a’case he had reported two years ago, in which he had beenable to remove the eyelash.-Mr. SNELL (Sheffield) spoke of case now under observation in which he had operated forcataract fourteen years since. There was now a cyst in the

anterior chamber which he thought might be of the samenature as that described.

Dr. RAYNBH D. BATTEN read a paper on the Diagnosisand Prognosis of l’athological Myopia. After reference toa former paper in which lie maintained that myopia wasfrequently the result of constitutional disease,l he saidthat the object of the present communication was to showthat a diagnosis of the constitutional cause of myopia maybe made from the condition of the fundus. Physiologicalmyopia should be confined to a simply refractive con-

dition, in which there is no fundus change of any kind.

Physiological myopia is not necessarily a refractive con-dition, and may even be associated with emmetropia or

hypermetropia, and is characterised by the formation ofcrescents, the stretching and distortion of the vessels,the presence of staphylomata, and by local and general dis-turbance of pigment. At present physiological myopia is notdistinguished from pathological myopia in its early stages,but only when the latter is far advanced. Pathologicalmyopia may be acute, chronic, progressive or stationary.The acute may end in arrest or become chronic, and may bethe result of various constitutional diseases. In the chronicform a diagnosis may be made between myopia due to cardio-vascular conditions, struma and inherited syphilis and un-healthy occupations. Pigmentary changes associated with’myopia: Marked pigment change at the margin of the cres-cent is a sign of acute myopia, and in the chronic form adistinction is made between a thin choroid, rendering thechoroidal vessels visible and occasionally associated with avery fine dust-like retinal pigment change and a choroid inwhich the pigment appears to be divided into islands ; theformer is attributable to cardio-vascular conditions; the latter,to strumous or specific disease. f3taphylomata: Four classes :(1) That in which the staphyloma is in the macular region ; i(2) that in which it occurs on the nasal side; (3) thatin which the optic dbc forms the deepest part of the

staphyloma; and (4) that in which it takes place towardsthe periphery. In all cases except the first the refractivecondition at the optical axis is no measure of the extent ofthe myopia. Peripheral myopia is a cause of astigmatism,by causing distortion of the lens and cornea. Distortionof the vessels : Three forms : (1) When the vessels are drawnfrom their normal course in relation to the optic disc ;(2) when they appear stretched and straightened ; (3) whenthey emerge by separate branches from the optic disc. Thedirection of the distortion of the vessels depends on the posi-tion of the staphyloma. This is particularly marked in casesof nasal staphyloma, the vessels being drawn to the nasalside of the optic disc and the macular branches having tobend back in order to supply that region. Distortion of thevessels is one of the early signs of commencing myopia. Thedirection of the distortion points to the position of thestaphyloma and the degree of the distortion or stretching ofthe vessels is an important factor in the prognosis. Central(physiological) cupping of the optic discs is a form of thestaphyloma and an early manifestation of commencingmyopia and responsible for the exit of the vessels from theoptic disc in numerous branches, the main trunk of thevessels having been drawn into the staphyloma. The earlypremonitory signs of myopia are central cupping, distortionof the vessels, commencing crescents and astigmatism.

Mr. SNELL (Sheffield) related two cases of Recurrent ThirdNerve Palsy associated with Migraine. One was in a youngman aged twenty-seven. Migraine had existed since the ageof ten, but only for the last seven years had the eye beenclosed with the attacks. The attacks occurred at first at in-tervals of about eight weeks, then at every two or three weeks,and lasted for three or four days. The palsy of the third nervewas practically complete ; ptosis and paralysis of the ocularmuscles, together with dilated pupil and palsy of accommoda-tion. The attacks commenced with vomiting and headache.The ocular palsy in the interval did not completely pass off,and the latest accounts, two years after he had last beenseen, indicated that the drooping of the lid was becomingmore permanent. The second case was in a girl agedeighteen. She had two attacks at intervals of four years,though migraine outbreaks continued in the interval. Eachtime she had made a perfect recovery, though the third nervewas not, at the worst, as completely involved as in the firstcase. Recovery was much longer in taking place. Mr. Snellgave additional particulars of a similar case he had broughtto the notice of the Society some years ago. He remarked

1 Ophthalmic Review, January, 1892.

Page 2: OPHTHALMOLOGICAL SOCIETY

140 NOTICES OF BOOKS.

that the shorter the interval the more rapid appeared to be therecovery in these cases, and also that the affection was

always monocular and showed no disposition to affect theother eye.

Living and Card Specimens.-Mr. WORK DODD : Pemphigusof Conjunctiva.-Mr. HOLMES SPICER : Ectopia Pupillas.—Dr. BATTEN: Pigmentary Moles in Retina.-Mr. MACKINLAY:Hyperostosis of SkulL-Mr. LAWFORD : Microscopic Sectionsof Sarcoma of Conjunctiva.-Mr. ADAMS FROST: (1) RetinitisProliferans; (2) Papillary Growth of Cornea.

election of o.fficen.-At the conclusion of the meeting theannual general meeting of the Society was held for the electionof officers for the ensuing session and to receive the report ofthe Council. The following officers were elected:-President:Dr. D. Argyll Robertson. Vice-Presidents : Mr. Edgar A. Browne(Liverpool), Mr. George Lawson, Dr. Stephen Mackenzie,Dr. William M. Ord, Mr. D. C. Lloyd Owen (Birmingham),Mr. Henry Power, Mr. Simeon Snell (Sheffield), and Mr. JohnTweedy. Treasurer: Mr. George Cowell. Secretaries : Dr.Charles E. Beevor and Mr. Gustavus Hartridge. Librarian :Mr. W. Adams Frost. Other Members of Council: Dr. ErnestClarke, Mr. F. Richardson Cross (Bristol), Dr. J. MackenzieDavidson (Aberdeen), Mr. Robert W. Doyne (Oxford), Dr. A.Hill Griffith (Manchester), Mr. R. J. Lunn, Dr. Joseph Nelson,Dr. J. A. Ormerod, Dr. W. C. Rockliffe (Hull), Dr. A. E.Sansom, Dr. G. H. Savage and Mr. A. Quarry Silcock. ’

After the customary vote of thanks to the retiring officersthe Society adjourned till October.

Notices of Books.Outlines of Practical Histology: a Manual for Students.

By WILLIAM STIRLING, M.D., Sc.D., Brackenbury Pro-fessor of Physiology and Histology in Owens College. With368 Illustrations. Second Edition, Revised and Enlarged.London: Charles Griffin and Co., Limited. 1893.-Dr. Stirlinghas done good service to the student in bringing out a secondedition of his "Outlines" containing an account of the mostrecent and important methods of examining the tissues. Theauthor has had large experience in teaching histology andhistological processes, and remarks that many methods havebeen tried and found wanting. The work is excellently illus-trated, very full directions are given for section cutting, andthe different kinds of microtomes, as those of Rutherfordand Cathcart, the Cambridge rocker, Malassez’s modificationof Roy’s instruments for cutting sections in air and undera fluid, Minot’s microtome, Thomas’s sledge microtome,Williams’s ice-freezing microtome, Swift’s ether-freezingmicrotome and Ranvier’s hand microtome are all describedand figured. Precise directions are given for the micro-

scopical examination of each tissue of the body. This

manual is a very useful work and is well up to date.

Das Gesetz der Transformation der Enochen. Von Dr.JULIUS WOLFF, Ausserordentlicher Professor der Chirurgie ander Berliner Universitat. (The Law of the Transformationof Bones. By Dr. Julius Wolff, Extraordinary Professor ofSurgery at the University of Berlin.) Berlin: August Hirsch-wald. 1892. -This is a very elaborate study of the arrangementof the bone lamellae in the head, neck and shaft of the femurin conditions of health and when altered by disease. Greatattention is paid to the influence of this arrangement on thefunction of the bone and upon fractures of the neck of thefemur. The work of Ward and Humphry and other Englishpioneers in this study receives due recognition, as well as thatof the author’s own countrymen. The subject is illustratedwith some admirable plates. In this and in other particularsDr. Wolff’s treatise is the most thorough and elaborate workdevoted to this subject.Mother and Child. By EDWARD P. DAVIS, A.M., M.D.,

and JOHN M. KEATING, M.D., LL.D. Philadelphia: J. B.

Lippincott Company. 1893. -This is a manual for mothers andnurses written by two medical practitioners of large experience.

This class of book is, as a rule, not very commendable, butDrs. Davis and Keating’s handbook is one of the best that wehave seen. The aim of the authors has been to supply abook which may be consulted in emergencies when the adviceof a competent medical or surgical authority is not obtain-able and to render intelligible to mothers matters concerningtheir own health and also the rearing and health of theirchildren. By the quiet study of such a book as this a motheror nurse may learn the reason and importance of all the little-details of treatment, and thus carry out more intelligently thc-instructions of the medical attendant. Dr. Davis deals ic,the first eighty pages with the evolution, the functions, ancduties of motherhood. In speaking of girlhood the trai2s.

atlantic origin of the book is observable in the followingrecommendation, which seems somewhat strange to our

English ideas : "A knowledge of the use of firearms is also.of decided value to a girl in enabling her to be calm andcourageous under various conditions of threatening danger."The second part by Dr. Keating occupies nearly 400 pagesand many of the chapters are most instructive. The

important question of the artificial feeding of infants is veryfully considered, special directions for the preparation ofsterilised and humanised milk being fully given. One of themost interesting chapters is that dealing with education andschool hygiene, which might be advantageously studied byall parents. The publishers are to be congratulated on theappearance of the volume.

A Forest Poem. By ROBERT T. COOPER, M.D. London vDavid Stott. 1893.-Dr. Cooper espouses in rough-and-readymetre the cause so effectively championed by the late Pro-fessor Arnaldo Cantani in his treatise " Pro Silvis " recentlycommented on in the columns of THE LANCET. His apologyfor the woods and forests is animated and well-inspired, butwe think he would have done better to have made it in prose.A versifier who rhymes "grasp " with "mask" and "ever"with "together " has still to master his tools.A Pocket Case-book for Practitioners and Students. By

ALEX. THEODORE BRAND, M.D. &c. London : Baillière,Tindall and Cox. 1892.-A satisfactory note-book is a

desideratum for all engaged in the active study or prac-tice of the profession. Most case-books, like the one beforeus, are very convenient for recording the first general con.

dition of a patient. The defect in all such books is the

absence of sufficient space for noting with sufficient fulnessthe course of a case subsequently to the preliminary exa-mination. Most practitioners select methods of their own 0fulfil this end. For all, however, who have no occasion tofollow from day to day or for a considerable period thecourse of a case, whether consultants, practitioners, or

students, this note-book will prove a convenient, durable andeven elegant medium for memoranda.

JOURNALS AND REVIEWS.

The Journal of Pat7wlogy and Bacteriology. No. IV. June,1893. Edinburgh and London : Young J. PentIand.—This-number completes the first volume of this valuable contri-bution to scientific periodical literature. It opens with someFurther Researches on some Parasitic Protozoa found inCancerous Tumours, by Dr. Armand Ruffer and Mr. H. G,Plimmer, adding fresh details and illustrations of the bodiesconsidered to be parasitic which the writers have discoveredwithin the cell nucleus as well as in the surrounding protoplastin mammary carcinoma. The positive proofs of the parasitise’of the bodies described have, however, still to be furnished-that is to say, if the ordinary meaning of the term "parasite’is to be adhered to. Dr. Berkley of Baltimore contributes apaper on the Intrinsic Nerves of the Kidney, which he htraced to their terminations around the glomeruli and beneaththe membrana propria of the urinary tubules. Dr. Soltao


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