NUMBER 1 JANUARY 1999 Original Articles Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP) T. Bratel, A. Wennlund & K. Carlstrom Acute adult asthma-assessment of severity and management and comparison with British Thoracic Society Guidelines S. FL Hart & A. C. Davidson Successive follow-up of chest computed tomography in patients with Mycobacterium avium-intracellulare complex Y. Obayashi. J. Fujita. I. Suemitsu.T. Kamei, M. Nii & J.Takahara 1 8 11 Prevalence of asthma and ‘probable’ asthma in the Asian population in Blackburn, U.K. L. P. Ormerod. P. Myers & R. J. Prescott A heated humidifier reduces upper airway dryness during continuous positive airway pressure therapy G. H. Wiest, G. Lehnert, W. M. BrQck. M. Meyer, E. G. Hahn &J. H. Ficker Acute safety of beclomethasone dipropionate in a new CFC-free propellant system in masthmatic patients J. G. Ayres. J. L. Simmons & P. Stampone A comparison of two long-acting P-agonists, oral bambuterol and inhaled salmeterol, min the treatment of moderate to severe 16 21 27 asthmatic patients with nocturnal symptoms B. Wallaert, P. Brun. J. Ostinelli. D. Murciano. F. Champel. B. Blaive. F. Montane. P. Godard &The French Bambuterol Study Group 33 Dyspnoea is associated with pulmonary function impairment in exposed workers A. Siracusa, P. L. Paggiaro, A. Forcina. D.Talini. A. Marabini. A. Benvenuti. G.Vregi SK M. Chan-Yaung Prescription and usage of long-term oxygen therapy in patients with chronic obstructive pulmonary disease in the Netherlands M. J. Kampelmacher, R. G.Van Kesteren. G. P. J. Alsbach. C. F. Melissant. H. J. Wynne. J. M. C. The differential effect of pentoxifylline on cytokine production by alveolar macrophages and its clinical implications N. Poulakis. G. Androutsos, D. Kazi, A. Bastas. A. Provata. C. Bitsak0u.T Kontozoglou. Cough induced by low pH Case Reports Effects of inhaled nitric oxide and aerosolized iloprost in pulmonary veno-occlusive disease M. M. Hoeper, C. Eschenbruch. C. Zink-Wohlfart. A. Schulz, S. Markworth, K. Pohl & H. Fabel 62 Pulmonary toxicity of chemotherapy and G/GM-CSF: a report of five cases L.-J. Couderc. S. Stelianides, I. Frachon. M. Stern, B. Epardeau. E. Baumelou. I. Caubarrere & 0. Hermine 65 Work-related asthma in an aircraft engine mechanic H. K. Makker &J. G. Ayres 69
Transcript
NUMBER 1 JANUARY 1999
Original Articles
Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP)
T. Bratel, A. Wennlund & K. Carlstrom
Acute adult asthma-assessment of severity and management and comparison with British Thoracic Society Guidelines S. FL Hart & A. C. Davidson
Successive follow-up of chest computed tomography in patients with Mycobacterium avium-intracellulare complex Y. Obayashi. J. Fujita. I. Suemitsu.T. Kamei, M. Nii & J.Takahara
1
8
11
Prevalence of asthma and ‘probable’ asthma in the Asian population in Blackburn, U.K. L. P. Ormerod. P. Myers & R. J. Prescott
A heated humidifier reduces upper airway dryness during continuous positive airway pressure therapy G. H. Wiest, G. Lehnert, W. M. BrQck. M. Meyer, E. G. Hahn &J. H. Ficker
Acute safety of beclomethasone dipropionate in a new CFC-free propellant system in masthmatic patients J. G. Ayres. J. L. Simmons & P. Stampone
A comparison of two long-acting P-agonists, oral bambuterol and inhaled salmeterol, min the treatment of moderate to severe
16
21
27
asthmatic patients with nocturnal symptoms B. Wallaert, P. Brun. J. Ostinelli. D. Murciano. F. Champel. B. Blaive. F. Montane. P. Godard &The French Bambuterol Study Group 33
Dyspnoea is associated with pulmonary function impairment in exposed workers A. Siracusa, P. L. Paggiaro, A. Forcina. D.Talini. A. Marabini. A. Benvenuti. G.Vregi SK M. Chan-Yaung
Prescription and usage of long-term oxygen therapy in patients with chronic obstructive pulmonary disease in the Netherlands M. J. Kampelmacher, R. G.Van Kesteren. G. P. J. Alsbach. C. F. Melissant. H. J. Wynne. J. M. C.
The differential effect of pentoxifylline on cytokine production by alveolar macrophages and its clinical implications N. Poulakis. G. Androutsos, D. Kazi, A. Bastas. A. Provata. C. Bitsak0u.T Kontozoglou.
Cough induced by low pH
Case Reports
Effects of inhaled nitric oxide and aerosolized iloprost in pulmonary veno-occlusive disease M. M. Hoeper, C. Eschenbruch. C. Zink-Wohlfart. A. Schulz, S. Markworth, K. Pohl & H. Fabel 62
Pulmonary toxicity of chemotherapy and G/GM-CSF: a report of five cases L.-J. Couderc. S. Stelianides, I. Frachon. M. Stern, B. Epardeau. E. Baumelou. I. Caubarrere & 0. Hermine 65
Work-related asthma in an aircraft engine mechanic H. K. Makker &J. G. Ayres 69
Letters to the Editor
Treadmill exercise duration and dyspnea recovery time in chronic obstructive pulmonary disease: effects of oxygen breathing and repeated testing
M. E. Dodd, C. S. Haworth &A. K.Webb 71
Reply to the Editor J. A. Marques-MagaI1anes.T W. Storer & C. 6. Cooper 71
Of Bourne, badgers, and a bovine ‘TB alert’ M. Hancox 72
Calendar 74
NUMBER 2 FEBRUARY 1999
Original Articles
Acute effects of nebulised epoprostenol in pulmonary hypertension due to systemic sclerosis K. Parameswaran. I. Purcell, M. Farrer, C. Holland, I. K.Taylor & N. P. Keaney 75
Sleep quality, carbon dioxide responsiveness and hypoxaemic patterns in nocturnal hypoxaemia due to chronic obstructive pulmonary disease (COPD) without daytime hypoxaemia
K. Sanc4ek.T Andersson.1 Bratel. G. Hellstrom & L. Lagerstrand 79
Health beliefs and compliance with inhaled corticosteroids by asthmatic patients in primary care practices C.V. Chambers. L. Markson, J. J. Diamond, L. Lasch 81 M. Berger 88
Clinical and laboratory features of lupus patients with complicating pulmonary disease T Mochizuki. S. Aotsuka 81 T Satoh 95
Agreement between spirometry and tracheal auscultation in assessing bronchial reponsiveness in asthmatic children A. B. Sprikkelman. J. P. Schouten, M. S. Lourens. H. S. A. Heymans & W. M. C. van
Aalderen 102
Snoring and myocardial infarction: a 4-year follow-up study C. Zamarron, F. Gude,Y Otero Otero & J. R. Rodriguez-Sulrez 108
Clinical features of non-specific interstitial pneumonia J. Fujita, I. Yamadori, I. SuemitsuT YoshinouchLY Ohtsuki,Y Yamaji,T Kamei. M. Kobayashi. Y Nakamura & J.Takahara 113
No relation of tuberculin reactivity with quantitative analysis of peripheral blood lymphocyte subsets in haemodialysis patients A. Y1ldiz.V. Akkaya. P. Yrldir, S.li3rk. N. GoreI. M. SQkrQ Sever & S. Badur
Report
Assessing lung deposition of inhaled medications. Consensus statement from a workshop of the British Association for Lung Research, held at the Institute of Biology, London, U.K. on 17 April 1998
Edited by N. J. C. Snell & D. Ganderton 123
Short Report
Nostril widening improves arterial oxygenation: a role for nasal nitric oxide? M. Herulf, J. 0. N. Lundberg & E. Weitzberg
Case Report
Hamman-rich syndrome ‘primed’ by radiation? S. P. Wharton & T K.Rogers ,136
Letters to the Editor
Corticosteroid treatment of asthma: now at the crossroads J. P. Scale & R. Donnelly
Reply to Drs Seale and Donnelly S. J. Szefler 142
Reply to Drs Seale and Donnelly H. Bisgaard
Reply to Drs Seale and Donnelly R. G. Dluhy
Reply to Drs Seale and Donnelly N. Barnes
Re: Asthma in the elderly: underperceived, underdiagnosed, and undertreated; a community survey 0. M. P. Jolobe 146
Calendar
NUMBER 3 MARCH 1999
Topical Review
Inhaled corticosteroids for adult asthma: impact of formulation and delivery device on relative pharmacokinetics, efficacy and safety R. J. Shaw 149
Original Articles
An observational study of inhaled corticosteroid withdrawal in stable chronic obstructive pulmonary disease N. A. Jarad, J. A. Wedzicha, P. S. Burge & P. M. A. Calverley for the ISOLDE Study Group 161
New formulation metered dose inhaler increases breath alcohol levels P. W. Barry 81 C. O’Callaghan 167
A national program for detection of I-antitrypsin deficiency in Italy M. Luisetti. G. Massi. M. Massobrio. P. Guarraci. F. M. Menchicchi. M. Beccaria & B. Balbi. for the Gruppo I. D.A. 169
Treatment of chronic obstructive pulmonary disease and its exacerbations in general practice M. Miravitlles. C. Mayordomo, M. Art&s. L. SBnchaz-Agudo, F. ,Nicolau & J.-L. SegO. on behalf of the EOLO Group 173
Effect of nebulized albuterol on circulating leukocyte counts in normal subjects R. L. Summers, M. Rodriguez. L.-A. Woodward. R. L. Galli &A. L. Causey 180
Eosinophilic inflammation assessed by induced sputum in corticosteroid-dependent asthma P.Tarodo de la Fuenta, M. Romagnoli, L. Carlsson. P. Godard. J. Bousquet & P. Chanez 183
The role of the expiratory phase in obstructive sleep apnoea 0. Resta. P. Guido.V. Picca. F. Scarpelli & M. P. Foschino
The effect of thoracentesis on lung function and transthoracic electrical bioimpedance B. Zerahn. B.Vrttrup Jensen, F. Olsen, J. Roland Petersen & I.-L. Kanstrup 196
Predictors of nocturnal oxygen desaturation in patients with COPD S. A. Little, M. M. Elkholy, G. W. Chalmers. A. Farouk, K. R. Pate1 & N. C.Thomson
Utility of blood cultures in community-acquired pneumonia requiring hospitalization: influence of antibiotic treatment before admission
J. Ch. Glerant. D. Hellmuth. J. L. Schmit. J. P. Ducroix & V. Jounieaux 208
Short Report
Consumption of Omega-3 and Omega-6 fatty acids in former East and West Germany and changes in East Germany after the reunification
Th. Hirsch & G. Kempe 213
Case Report
A thoracic complication of hereditary multiple exostoses in an adult J. A. Nick, D. A. Lynch, M. I. Schwarz & M. E. Hanley 217
Letters to the Editor
A critical reappraisal of transmission routes for bovine TB in cattle A. Hancox
Does an inhaled B-adrenergic or anti-cholinergic agent improve gas exchange at rest and during exercise in patients with COPD? S. Teramoto & Y. Ouchi
Erratum 224
Calendar
NUMBER 4 APRIL1999
Editorial
Should long-acting /3z-agonists be considered an alternative first choice option for the treatment of stable COPD? M. Cazzola & M. G. Matera 227
Original Articles
Efficacy of once- and twice-daily administration of budesonide via Turbuhaler@ as initial therapy in patients with mild persistent asthma
I. Herjavecz. P. Blomqvist & A. Serrano 230
A comparison of the efficacy of long-acting p-agonists: eformoterol via Turbohale? and salmeterol via pressurized metered dose inhaler or Accuhaler@, in mild to moderate asthmatics
L. M. CampbelLT. J. Anderson, M. R. Parashchak. C. M. Burke. S. A. Watson & M. L.Turbitt. on behalf of the FORCE research group 236
Inhaled beclomethasone (BDP) with non-CFC propellant (HFA 134a) is equivalent to BDP-CFC for the treatment of asthma J. Milanowski. J. Qualtrough &V L. Perrin 245
The efficacy and safety of a new ciprofloxacin suspension compared with co-amoxiclav tablets in the treatment of acute exacerbations of chronic bronchitis
Analysis of pleural fluid in idiopathic spontaneous pneumothorax; correlation of eosinophil percentage with the duration of air in the pleural space
H. J. M. Smit. M. M. van den Heuvel. S. B. Barbierato, R. J. H. Beelen & P. E. Postmus
Serum leptin in children with asthma treated with inhaled budesonide C. Heuck & 0. D. Wolthers
Increased serum concentrations of conjugated diens and malondialdehyde in patients with pulmonary tuberculosis S. Kwiatkowska. G. Piasecka. M. Zieba, W. Piotrowski & D. Nowak
262
268
272 !a%
Methacholine-induced fall in forced vital capacity as a marker of asthma severity
Long-term (3-year) economic evaluation of intensive patient education for self-management during the first year in new asthmatics inen H. Sintonen.V.Vilkka & H. Tukiainen 283
Re: Ventilation in a Birmingham intensive care unit 1993-1995: outcome for patients with chronic obstructive pulmonary disease A. C. Davidson & D. F.Treacher
Reply to Drs Davidson and Treacher A. Hill, M. Wildman. R. Hopkinson & D. Stableforth
Corticosteroid treatment of asthma: now at the crossroads C. Hallett /
Calendar
Forthcoming papers 296
NUMBER 5 MAY 1999
Special Issue Featuring Chronic Bronchitis and Chronic Obstructive Pulmonary Disease: Finnish National Guidelines for Prevention and Treatment 19994007
Guidelines
Chronic bronchitis and chronic obstructive pulmonary disease: Finnish National Guidelines for Prevention and Treatment 1998-2007 L. A. Laitinen, K. Koskela and the Expert Advisory Group Listed in the Foreword 297
Original Articles
Compliance with LTOT and consumption of mobile oxygen T. Ringbsek. P. Lange & K.Viskum
Lactate dehydrogenase isoenzyme analysis for the diagnosis of pleural effusion in haemato-oncological patients I. S. Lossos. 0. Intrator, N: Berkman & FL Breuer 338
Peak inspiratory flow through Turbuhaler@ in chronic obstructive airways disease M. H. Dewar. A. Jamieson. A. McLean & G. K. Crompton 342
The safety and success rate of sputum induction using a low output ultrasonic nebuliser C. J. Hunter, R-Ward. G. Woltmann. A. J. Wardlaw & I. D. Pavord
Environmental asbestos exposure and malignant pleural mesothelioma M. Metintas. N. Gzdemir, G. Hillerdal. I. Ucgun. S. Metintas, C. Baykul, 0. Elbek, S. Mutlu & M. Kolsuz
Survey of knowledge of simple pulmonary function tests (PFTs) amongst trainee doctors in England M. Mamun 356
Midazolam sedation to produce complete amnesia for bronchoscopy: 2 years’ experience at a district general hospital T J. Williams 81 P. E. Bowie 361
Letters to the Editor
Inhaled beclomethasone dipropionate symposium S. P. Newman & G. R. Pitcairn 366
Reply to Drs Newman and Pitcairn C. Leach 367
Erratum
Calendar
Forthcoming papers 372
NUMBER 6 JUNE 1999
Original Articles
Pneumocystis carinii pneumonia in HIV-infected patients: effect of steroid therapy on surfactant level
J. R. Dichter. J. D. Lundgren,T L. Nielsen, B. N. Jensen, J. Schattenkerk,T L. Benfield, M. Lawrence &J. Shelhamer
Delayed chest radiographs and the diagnosis of pneumothorax following CT-guided fine needle aspiration of pulmonary lesions
R. P. Byrd Jr, C. Fields-Ossorio & T M. Roy
The effect of gestational parity on FEV, in a group of healthy volunteer women
R. Harik-Khan, R. A. Wise, C. Lou, C. t-l. Morrell. L. J. Brant &J. L. Fozard 382
Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with
stable chronic obstructive pulmonary disease: no significant effect of cigarette smoking
D. Nowak, M. Kasielski, A. Antczak.T. Pietras & P. Bialasiewicz 389
Are doctors still failing to assess and treat asthma attacks? An audit of the management of acute attacks in a Health District
H. Pinnock, A. Johnson, P.Young & N. Martin
The cost-effectiveness of inhaled fluticasone propionate and budesonide in the treatment of asthma in adults and children
N. C. Barnes, R. M. A.Thwaites 81 M. J. Price
397
402
Familial sarcoidosis in Finland and Hokkaido, Japan-a comparative study
A. Pietinalho, M. Ohmichi. M. Hirasawa.Y. Hiraga. A-B. Lofroos & 0. Selroos 408
The role of codeine phosphate premeditation in fibre-optic bronchoscopy under insufficient local anaesthesia and midazolam sedation
Y. Tsunezuka. H. Sato,T Tsuki0ka.Y. Nakamura & Y. Watanabe 413
&agonist-induced inhibition of neutrophil chemotaxis is not associated with modification of LFA-1 and Mac-l expression or with
impairment of polymorphonuclear leukocyte antibacterial activity
M. Silvestri. S. Oddera, S. Lantero 81 G. A. Rossi 416
Improved targeting of beclomethasone diproprionate (250 pug metered dose inhaler) to the lungs of asthmatics with the Spacehaler
S. P. Newman, K. P. Steed, G. Hooper, J. I. Jones & F. C. Upchurch 424
Short Communication
Autologous blood-patch pleurodesis for secondary spontaneous pneumothorax with persistent air leak
M. Ando, M.Yamamoto, C. Kitagawa, A. Kumazawa, M. Sato. K. Shima. A. Watanabe, K. Shimokata & Y. Hasegawa 432
Case Report
High-frequency oscillatory ventilation in RSV bronchiolitis patients
E. L. I. M. Duval. P. L. J. M. Leroy, R. J. B. J. Gemke & A. J. vanVught
Book Review 441
Calendar 442
Forthcoming Papers
NUMBER 7 JULY 1999
Original Articles
Regular albuterol or nedocromil sodium-effects on airway subepithelial tenascin in asthma A. Altraja. A. Laitinen, S. Meriste. S. Marran.T. MLirtson. l-l. Sillastu & L. A. Laitinen
Clinical value and cost of a respiratory sleep-related breathing disorders screening service for snorers referred to a District General Hospital ENT department
S. J. Lloyd-Owen, A. Crawford. M. FL Partridge & C. M. Roberts 454
Safety and cellular assessment of bronchial brushing in airway diseases M. Romagnoli. LVachier, A. M.Vrgnola. P. Qodard. J. Bousquat & P. Chanez ., / 461
Performance of a short lung-specific health status measure in outpatients with chronic obstructive pulmonary disease K. Stavem. J. Erikssen &J. Boe 467
Inhaled antibiotic therapy in non-cystic fibrosis patients with bronchiectasis and chronic bronchial infection by Pseudomonas
aeruginosa
R. Orriols. J. Roig. J. Ferrer, G. Sampol. A. Resell. A. Ferrer & A.Vallano
Chronic obstructive pulmonary disease, with and without alpha-1-antitrypsin deficiency: management practices in the U.K. A.% Hill, E. J. Campbell, A. Milford Ward & R. A. Stockley
476
481
Cutaneous delayed-type hypersensitivity reactions in smokers with chronic bronchitis and recurrent exacerbations: comparison with asymptomatic smokers and never-smokers
I. Qvarfordt. G. C. Riise. S. Larsson. G. Almqvist &J. Rollof 491
Bronchoalveolar lavage cell profiles in Wegener’s granulomatosis A. Schnabel. M. Reuter, K. Gloeckner. J. Miiller-Quernheim & W. L. Gross 498
Elevated plasma brain natriuretic peptide levels in chronic respiratory failure with car pulmonale M. Band0.Y Ishii,Y Sugiyama & S. Kitamura ‘. ’
Associations between an asthma morbidity index and ideas of fright and bother in a community population K. Jones. R. Cleary & M. Hyland
Calendar 520
Forthcoming Papers 521
Corrected Reprint
A comparison of the efficacy of long-acting j&agonists: eformaterol via Turbohaler@ and salmeterol via pressurized metered dose inhaler or Accuhaler@, in mild to moderate asthmatics
L. M. Campbel1.T. J. Anderson, M. R. Parashchak, C. M. Burke, S. A. Watson & M. L.Turbitt, on behalf of the FORCE Research Group
NUMBER 8 AUGUST1999
Original Articles
Assessment of respiratory function: influence of spirometry reference values and normality criteria selection S. Quadrelli. A. Floncoroni & G. Montiel
Elimination of CO1 in patients with carbonic anhydrase II deficiency, with studies of respiratory function at rest K. Taki. H. Kato & I. Yoshida
Oropharyngeal Gram-negative bacillary carriage in chronic obstructive pulmonary disease: relation to severity of disease K. J. Mobbs. H. K. F. van Saene. D. Sunderland & P. D. 0. Davies
536
540
Ventilatory function of healthy, urban, non smoking, Pakistani young adults aged 18-24 years M. A. Nadeem. S. N. Raza & M. A. Malik 546
Exhaled nitric oxide and its relationship to airway responsiveness and atopy in asthma D. LQdviksd6ttir, C. Janson. M. Htigman, H. HedenstrGm. E. Bjiirnsson & G. Boman on behalf of the BHR-study group 552
Clinical and serological studies of tuberculosis patients in Argentina receiving immunotherapy with Mycobacterium vaccae (SRL 172) D. Dlugovitzky, 0. Bottasso. J. C. Dominino. E.Valentini, R. Hartopp, M. Singh. C. Stanford & J. Stanford 557
A comparison of the expression of lymphocyte activation markers in blood, bronchial biopsies and bronchoalveolar lavage: evidence for an enrichment of activated T lymphocytes in the bronchoalveolar space
A. Ekberg-Jansson, E. Arv& 0. Nilsson. C.-G. Lijfdahl & 6. Andersson 563
Detection of non-infectious conditions mimicking pneumonia in the intensive care setting: usefulness of BAL fluid cytology J. A. Jacobs, E. I. G. B. De Brauwer. G. Ramsey, N. A. M. Cobben. Sj. SC. Wagenaar. A. J. A. M. van derVen. C. A. Bruggeman & M. Drent
Effect of inhaled nitric oxide on pulmonary function in cystic fibrosis F. Ratjan, S. G&rtig, H. G. Wiesemann & H. Grasemann
Asthma nurse practice-resource-effective approach in asthma management M. Lindberg, J. Ahlner. M. Mijller &T. Ekstri5m 584
Serum ECP and MPO, but not urinary LTE4, are associated with bronchial hyper-responsiveness J. Hedman. E. Moi1anen.T Poussa & M. M. Nieminen
Case Report
589
Near normalization of spirometry in a subject with severe emphysema complicated by amiodarone lung D. W. Cockcroft & K. L. Fisher
Calendar
Forthcoming Papers
597
601
602
NUMBER 9 SEPTEMBER 1999
Original Articles
Dose-ranging study of a new steroid for asthma: mometasone furoate dry powder inhaler D. I. Bernstein, R. 6. Berkowitz, P. Chervinsky, D. J. Dvorin, A. F. Finn. G. N. Gross, M. Karetzky, J. P. Kemp. C. Laf0rce.W. Lumry. L. M. Mendelson, H. Nelson. D. Pearlman. G. Rachelefsky, P. Ratner, L. Repsher, A.T. Segal. J. C. Selner, G. A. Settipane. A. Wanderer, F. M. Cuss, K. B. Nolop & J. E. Harrison 603
The effect of high-dose fluticasone propionate and budesonide on lung function and asthma exacerbations in patients with severe asthma
J. H. Heinig. L. P. Boulet. L. Croonenborghs & M. J. Miillers 613
The role of fibre-optic bronchoscopy in solid organ, transplant patients with pulmonary infections S. Nusair & M. R. Kramer .I 621
Evaluation of bronchodilator response in patients with airway obstruction S. A. Quadrelli. A. J. Roncoroni & G. C. Montiel 630
Role of the endogenous prostaglandin Es in human lung fibroblast interleukin-1 1 production S. Matsui. N. yamashita.T Mine, H.Taki. E. Sugiyama, R. Hayashi. M. Maruyama & M. Kobayashi 637
Volume calibration alone may be misleading G. van den Boom, L. M. van der Star, H. Folgering. C. P. van Schayck & C. van Wee1 643
cc,-Antitrypsin TAQ I polymorphism and aI-antichymotrypsin mutations in patients with obstructive pulmonary disease M. G. Benetazzo, L. S. Gil& C. Bombieri, G. Malerba. M. Massobrio, P. F. Pignatti & M. Luisetti 648
Re-examination of the diagnostic criteria of tropical pulmonary eosinophilia J. H. L. Cooray & M. M. lsmail 655
The active cycle of breathing techniques-to tip or not to tip? N. M. Cecins. S. C. Jenkins, J. Pengelley & G. Ryan
Production of interleukin-10 by alveolar macrophages from lung cancer patients H. yanagawa. E. TakeuchLY Suzuki. M. HanibuchLT Haku.Y. Ohmoto 81 S. Sone
Case Report Bronchocentric granulomatosis due to Aspergih terreus in an immunocompetent and non-asthmatic woman S.Yano, S. Shishido, K. Kobayashi, H. Nakano &Y Kawasaki 672
Calendar 675
Forthcoming Papers 676
NUMBER 10 OCTOBER 1999
Topical Review
The problems of treating adolescent asthma: what are the alternatives to inhaled therapy?
J. Price &J. Kemp 677
Original Articles
Office spirometry: temperature conversion of volumes measured by the Vitalograph-R bellows spirometer is not necessary
F. Madsen, L. Frdlund, C. S. Ulrik & A. Dirksen
Oral steroid-sparing effect of two doses of nebulized fluticasone propionate and placebo in patients with severe chronic asthma
685
An investigation of factors limiting aerobic capacity in patients with ankylosing spondylitis
haracteristics of users of inhaled long-acting &agonists in a Southern European population
J. Castellsague, L. A. Garcia-Rodriguez, S. Perez-Gutthann, L. Agostinis, C. Cattaruzi 81
teroid reversibility test followed by inhaled budesonide or placebo in outpatients with stable chronic obstructive pulmonary disease
T Senderovitz, J.Vestbo, J. Frandsen, N. Maltbask, M. Ndrgaard, C. Nielsen, J. P Kampmann for 715
Non-invasive evaluation of lower airway inflammation in hyper-responsive elite cross-country skiers and asthmatics
719
Chronic respiratory symptoms, von Willebrand Factor and longitudinal decline min FEVt 726
Exercise-induced respiratory symptoms are not always asthma
0. Lowhagen, M. Arvidsson. P. Bjarneman & N. Jorgensen 734
Lack of effects of moderate-high altitude upon lung function in healthy middle-age volunteers
P. Casan, BTogores, J. Giner, I. Nerin, F. Drobnic, L. Borderias, J. Caminero, F. Duce &A. G. N. Agusti
Inflammatory markers in acute exacerbations of obstructive pulmonary disease: predicitve value in relation to smoking history
I. Dahlirn. C. Janson. E. Bjornsson, G. Stalenhaim. C. G. B. Peterson & P.Venge
Short Communication
Promoter variation of tumour necrosis factor-alpha gene: possible high risk for chronic bronchitis but not diffuse panbronchiolitis
N. Keicho. M. Emi. K. Nakata,Y Taguchi. A. Azuma, K.Tonkunaga. N. Ohishi & S. Kudoh 752
Case Report
A case of non-specific interstitial pneumonia associated with primary lung cancer: possible role of antibodies to lung cancer cells in the
pathogenesis of non-specific interstitial pneumonia
I. YamadorLT
Calendar 757
Forthcoming Papers 758
NUMBER 11 NOVEMBER 1999
Topical Reviews
Directly observed therapy for the treatment of tuberculosis-evidence based dosage guidelines R. Bednall. G. Dean 81 N. Bateman 759
Compliance in asthma G. M. Cochrane. I?. Horne & P. Chanez 763
Original Articles
Intra-tracheal delivery strategy of gentamicin with partial liquid ventilation A. B. Cullen, C. A. Cox. S. J. Hipp. M. R. Wolfson &T. H. Shaffer
Current and future medical costs of asthma and chronic obstructive pulmonary disease in the Netherlands M. P. M. H. Rutten-van Mijlken. M. J. Postma. M. A. Joore. M. L. L.Van Genugten. R. Leidl & J. C. Jager
Pharmaceutically-based severity stratification of an asthmatic population F.T. Leone. J. R. Grana. P. McDermott, S. MacPherson. N. A. Hanchak &J. E. Fish 788
The effects of time delay and temperature on capillary blood gas measurements R. G. Dent, D. R. Boniface. J. Fyffe 81 Zyousef 794
Increasing prevalence of asthma but not of chronic bronchitis in Finland? Report from the FinEsS-Helsinki study P. Pallasaho. B. LundbBck. S. L. LLispl. E. Jiinsson. J. Kotaniemi. A. R. A. Sovijiirvi & L. A. Laitinen 798
Does the ‘Oxygen cost diagram’ reflect changes in six minute walking distance in follow up studies? J. P. Janssens. E. Breitenstein.T Rochat & J. W. Fitting 810
ADAi/ADAp ratio in pleural tuberculosis: an excellent diagnostic parameter in pleural fluid E. Perez-Rodriguez. I. J. Perez Walton, J. J. Sanchez Hernandez. E. Pallares. J. Rubi, D. Jimenez Castro & G. Diaz Nuevo
Differences in mortality between patients attending the emergency room services for asthma and chronic obstructive pulmonary disease J. Garcia-Aymerich, J. Sunyer, A. Domingo-Salvany. D. Mcfarlane. N. MontellB. G. P6rez & J. M. Ant6 822
Induced sputum compared to bronchoalveolar lavage for evaluating patients with sarcoidosis and non-granulomatous interstitial lung disease
E. Fireman. I.Topilsky, J. Greif,Y Lerman.Y Schwarz. A. Man 81 M.Topilsky 827
Prophylactic antibiotic therapy is associated with an increased prevalence of Aspergilh colonization in adult cystic fibrosis patients J. Bargon. N. Dauletbaev, B. Ktihler, M. Wolf, H.-G. Posselt 81 T 0. F. Wagner 835
Case Report
Demonstration of tracheal stenosis by computed tomography of different modalities and their comparisons: report of one child with congenital stridor and wheezing
M.-L. Lee, I.-S. Chiu, S.-J. Chen &W.-T Chaou 839
British Association for Lung Research Abstracts
Genetic factors in lung disease: from gene hunting to gene therapy A.1
Calendar 842
Forthcoming Papers 843
NUMBER 12 DECEMBER 1999
Topical Reviews
Infection in acute exacerbations of chronic bronchitis: a clinical perspective R. C. Read 845
Asthma and asthma-like disorders 0. Lowhagen 851
Patient factors and compliance with asthma therapy N. Clark, P. Jones, S. Keller & P. Vermeire 856
Original Articles
Salmeterol reduces the need for inhaled corticosteroid in steroid-dependent asthmatics L. P. Nielsen, B. Pedersen, P. Faurschou, F. Madsen, J.T R. Wilcke & FL Dahl 863
Evidence of mild respiratory disease in men with congenital absence of the vas deferens C. Castellani. A. Bonizzato. U. Pradal. M. Filicori. C. Foresta, 0. B. La Sala & G. Mastella 869
Salmeterol/fluticasone propionate (SO/500 pg) in combination in a Diskus@ inhaler (Seretide@) is effective and safe in the treatment of steroid-dependent asthma
M. Aubier. W. R. Pieters, N. J. J. Schlijsser & K-O. Steinmetz 876
Pulmonary damage after modest exposure to zinc chloride smoke B. Zerahn. A. Kofoed-Enevoldsen, B.V. Jensen, J. Mdlvig. N. Ebbehej, J. S. Johansen & I.-L. Kanstrup 885
Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A* receptor antagonist in asthmatic patients?
H. Tanaka,T 1garashi.T Saitoh, S. Teramoto. N. Miyazaki, S. Kaneko, M. Ohmichi & S. Abe 891
The impact of pleurodesis in malignant effusion on respiratory function V. Ukale. D. Bone, G. Hillerdal, K. Cederlund. 0. Widstriim & F. Larsen 898
Feasibility of spirometry and reversibility testing for the identification of patients with chronic obstructive pulmonary disease on asthma registers in general practice
C. Griffiths. G. Feder, J. Wedzicha. G. Foster, A. Livingstone & G. Singh Marlowe 903
Influence of higher than conventional doses of oxitropium bromide on formoterol-induced bronchodilation in COPD M. Cazzola. M. G. Matera. F. Di Perna. C. Califano. M. D’Amato & G. Mazzarella
Nitric oxide metabolites in patients with asthma: induced sputum versus blood A.-S. Jang & I.-S. Choi
Reports
Early house moves, indoor air, heating methods and asthma F?. C. M. Jones, C. R. Hughes. D. Wright &J. H. Baumer 919
A confidential enquiry into certified asthma deaths in the North of England, 1994-96: influence of co-morbidity and diagnostic inaccuracy
K. Jones. W.T. Bert-ill, C. L. Bromly & D. J. Hendrick 923
