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Station 1

This is the

peripheral smear of

a 12 year old

female child who

presented with

pancytopenia. Also

shown is the bonemarrow picture of

this child. Kindly

give the diagnosis

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Answer Station 1

Megaloblastic anemia

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Station 2

What ancillary tests will you do to clinch

the diagnosis? Give any two.

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Answers Station 2

LDH

S. Bilirubin

Vit B12 level S. Folic Acid levels

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Station 3

What are the recommended dosages for

the treatment of Vitamin B 12 and Folic

Acid deficiency

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Station 4

This is the peripheral

smear of a patient who

came with purpuric spots

and hemoglobin of 10,

mildly hypochromic

microcytic picture.

Identify the cell shown

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Answer Station 4

Giant Platelets

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Station 5

This is the peripheral smear of a 4 year old child

who presented with a Hb of 10gm/dL, TLC 9000,

Platelet 30,000 and no organomegaly or

lymphadenopathy. The child had purpura but nosignificant bleed. Was stable. Parents are well

educated and live in Delhi.

What will be the drug to treat this patient?

Will you do a bone marrow in this patient?

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Answers Station 5

No treatment is required. Just observation

No need for bone marrow

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Station 6

Kindly counsel the parents of this child

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Answers Station 6

Introduces himself and tries to make the parents

comfortable.

Talks about the disease ITP

Talks about the possibility of any other disease

Talks about the need for injury prevention

Tells about the warning signs when they have to

report to the hospital Talks about the self limiting nature of the

disease

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Station 7

Hb 10

MCV 58 MCH 23

MCHC 32

RBC Count 5.4 RDW 13.5

P/Smear As shown

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Questions Station 7

Kindly comment on the peripheral smear

and identify the cell shown.

Give your probable diagnosis in the

patient with the above indices and

P/Smear

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ANSWER 7

:MICROCYTIC HYPOCHROMICANAEMIA WITH TARGET CELL

: BETA THALASEMIA TRAIT

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Station 8

1. Identify the spot (Arrow)

2. Name the agents

used to stain this cell

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Answers Station 8

Myeloblast with 3 prominent nuclei

Stains- Myeloperoxidase, Non specific

esterase and Sudan black

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Station 10

2 yr old child was evaluated foranemia and found to have areticulocyte count of 20% and a

PCV of 25%. Calculate the Reticulocyte

production index takingmaturation time as 2 days andassuming a normal PCV of 0.45

What does this signify? (In termsof production rate)

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Answers Station 10

RPI = Reticulocyte % x Observed PCV(0.25)

Maturation time x Normal PCV (0.45)

It comes = 5.5

It signifies that production has increased to 5.5 times

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Station 11

18 month old child

with pallor and

cutaneous markers

at the back with anabnormal skeletal

profile. P/S was

consistent with

macrocytic anemiaand pancytopenia.

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Questions Station 11

What is the most probable diagnosis?

Name the cutaneous marker.

What malignancies are expected in thispatient?

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Answers Station 11

Fanconi anemia

Caf au lait spot

Acute leukemia

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Station 12

Identify the spot

with arrow?

Define it

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Answer Station 12

Band cell

Its a cell of neutrophil (Leukocyte)

series in which the nucleus appears to

be folded and the joining isthmus of the

two lobules is > 1/3rd of the maximum

width of the largest lobule

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Station 13

Give the full form of SQUID and what it

is best used for?

Give the full form of NESTROF and

what it is used for?

What is the principle used in NESTROF

test?

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Answer Station 13

SQUID- Super-conducting QuantumInterference Device & Provides the mostaccurate and best-validated non-invasivemethod for measuring liver iron

NESTROF- Naked Eye Single Tube Red CellOsmotic Fragility Test and it is usefull inscreening for beta-thalassaemia and some ofthe common haemoglobinopathies

The principle of NESTROF is based on thelimit of hypotonicity which the red cell canwithstand.

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THANK YOU!!!

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This child has a

history of polyuria,frequent otitis mediaand bone pains

What is the mostprobable diagnosis?

Name of theepidermis layerwhere this cell isfound?

What does it

contain?

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Station 15

Identify the spot

in the marrow

What is the

treatment for

this? Name two

drugs

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Answer Station 15

LD Body

Amphotericin B & Sodium Stibogluconate,

Multifosein