Out With the Old and In With the New, Again?
Out With the Old, In With the New
Current Standard of Care
NEUTRINO and FISSION SOF + RBV ± pegIFN for Treatment-naive Patients
NEUTRINO and FISSION SOF + RBV ± pegIFN for Treatment-naive Patients
FUSIONSOF + RBV ± pegIFN in Treatment-experienced Patients With G2,3 HCV
VALENCESOF + RBV for 12 Weeks or 24 Weeks in G2 or G3 HCV Infection
QUEST 1 and 2Q80K Variant Adversely Affects SVR12 of SMV-based Therapy
COSMOS SOF + SIM ± RBV for G1 HCV-infected Patients by Fibrosis Stage
2014 AASLD HCV Treatment Guidelines
ION-1On the Road to IFN-free Therapy for G1 HCV
Infection
ION-3 8 Weeks or 12 Weeks of SOF/LDV for Treatment-
naive G1 HCV Infection
ION-2SOF/LDV in G1 HCV-infected Patients Failing
PegIFN/RBV ± DAA
HALLMARK-DUALPhase 3 Trial of the All-oral Regimen DCV + ASV
for G1b HCV Infection
SAPPHIRE IABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV
for G1 HCV Infection
SAPPHIRE IIABT-450/r/Ombitasvir + Dasabuvir + RBV (3D)
G1 HCV
TURQUOISE IIABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV in
Cirrhosis
The Past And Future of HCV Therapy
Abbreviations
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References
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