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Pat Martin / Taubman Medical Library / 2006 Evidence-Based Medicine Time Saving Steps.

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Pat Martin / Taubman Medical Library / 2006Pat Martin / Taubman Medical Library / 2006

Evidence-Based Evidence-Based MedicineMedicine

Time Saving StepsTime Saving Steps

Adapted from R. Brian Haynes, Of studies, synthesis, synopses and systems: the “4S’ evolution of services for finding current best evidence. ACP Journal Club, 134(2)

March/April 2001, pp A-11-A-13.

From the top down…

Systems: The best, most recent evidence linked through the patient record – ideal but not yet a reality

As close as we can get…Frequently updated electronic

textbooksRegularly updated clinical practice

guidelinesThese lack the ideal functionality

to filter the evidence based on patient characteristics

From the top down…

Synopses: Synopses of individual studies and reviews

ACP Journal Club

It’s a matter of time…

From the top down…

Syntheses: Summaries based on rigorous searches for evidence

Cochrane Library

Ovid EBMR

From the top down…

Original Studies:

Randomized control trials

Clinical trials

Comparative studies

Multicenter studies

Epidemiological studies

Case:

78 year old divorced African American man who presents with his third episode of major depression after a myocardial infarct. He previously responded to nortriptyline. After his last cardiac event, however, he

developed conduction delay such that tricyclics are now contraindicated.

You need to treat and must consider treatment options.

Question 1: Is there pharmacological intervention which is safer than tricyclic antidepressants in this 78 year old man, post-MI?

Question 2: In a 78 year old man, s/p MI with recurrent major depressive disorder, would psychotherapy treatment vs. a trial of

antidepressant medication be effective?

From the top down…

Systems: The best, most recent evidence linked through the patient record – ideal but not yet a reality

Frequently updated electronic textbooks such as ACP MedicineACP Medicine is a continually updated,

evidence-based reference of internal medicine.

Regularly updated clinical practice guidelines

www.lib.umich.edu/taubman

From the top down…

Systems: The best, most recent evidence linked through the patient record – ideal but not yet a reality

Frequently updated electronic textbooks such as ACP MedicineACP Medicine is a continually updated,

evidence-based reference of internal medicine.

Regularly updated clinical practice guidelinesUMHS guidelinesNational Guidelines Clearinghouse

www.guideline.gov

From the top down…

Synopses: Synopses of individual studies and reviews

ACP Journal Club

From the top down…

Syntheses: Summaries based on rigorous searches for evidence

Cochrane Library

Ovid EBMR

From the top down…

Original Studies:

Randomized control trials

Clinical trials

Comparative studies

Multicenter studies

Epidemiological studies


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