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PATHOLOGICAL SOCIETY OF LONDON. TUESDAY, JAN. 1ST, 1867

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13 In an appendix the author gave the details of M. P. Broca’s I unpublished case of ligature of the subclavian artery for inno- minate aneurism, and also a table of the various cases of distal ligature for aneurism of the root of the neck which have been recorded. Mr. HoLMES said that he was glad to have the opportunity of bearing his testimony to the very gratifying success ob- tained in this case, which he thought Mr. Heath had accu- rately described as unique in the annals of surgery. He wished to defend the accuracy of the views in his article on aneurism in the " System of Surgery" from the imputations which Mr. Heath appeared to cast upon them. In fact, however, Mr. ! Heath, while saying that he "was somewhat in the dark" as to the proposals made for operation in these cases of supposed innominate aneurism, had himself, in his subsequent remarks, completely vindicated the accuracy of the statement in the "System of Surgery." The operations proposed were really as there stated. First, the simultaneous ligature of the com- mon carotid and first part of the subclavian, as necessitated by a logical following of the proposal known by Brasdor’s name, and as shown by Mr. Heath to have been practised in Rossi’s operation. This operation Mr. Holmes had spoken of as too dangerous to be justifiable, and Rossi’s case so far bore out that view. Secondly, the ligature of the carotid alone, which does not seem to hold out sufficient hope of success to justify the risk to which it exposes the patient; and thirdly, the ligature of the carotid and third part of the subelanian. Before Mr. Heath’s case this double ligature had only been practised at a considerable interval of time between the two operations, and Mr. Fearn’s was the only case in which success was claimed ; but his account was obscurely worded, and led Mr. Holmes to doubt the reality of the cure. Mr. Fearn’s preparation now before the Society showed, however, that as far as the disease in the innominate artery went it had been arrested, and probably soundly cured, and the pressure upon the trachea and threatened bursting into that tube obviated, so that the life of the patient was saved for the time. But the preparation also showed, as it seemed to him, that the aorta partook largely in the disease, and that, therefore, though life had for the time been saved, the disease could not be said in strictness to be cured. So in Mr. Heath’s case also. His account of the consultations prior to operation showed how great a doubt there was as to whether the aorta was or was not the seat of disease in this woman, and his perfectly I accurate and frank description of her present condition I showed also that the disease is far indeed from being cured, ’’ though its progress towards the trachea and towards the nervous cords forming the plexus had been arrested. But it is well known that these tubular aneurisms or aneurismal dilatations involving the aorta, innominate, and perhaps also subclavian arteries, will go on sometimes for an indefinite period without material alteration, and that the sacciform. dilatations or buds projecting out from them (like that in Mr. Fearn’s case) will sometimes, and perhaps not very infrequently, undergo spontaneous cure. Instances of these events were quoted from the recent practice of St. George’s Hospital. Considering, therefore, the great difficulty of diagnosis, the risk of finding the arteries diseased where exposed for opera- tion, the great likelihood of serious disease in the aorta or even the heart also, and the possibility of spontaneous cure, or cure by appropriate regimen, it seems prudent not to under- take these operations without the gravest consideration, and in circumstances which can but rarely present themselves. Perhaps the best indication for operation would be the relative amount of pressure on the trachea compared with that of the general symptoms. That is, when the patient is otherwise in moderately good health, but suffers much from dyspuaea, and appears likely to die soon from rupture of the aneurism in this direction, the question of arresting it by ligature of the arteries of the right side might be considered, but in any case it must be regarded rather as palliative than as curative. Mr. Holmes concluded by congratulating Mr. Heath on the success of an operation of such difficulty and magnitude, and which really appeared to have saved, or at least prolonged, the patient’s life. Mr. SAVORY referred to a remark in the report of the case which was to the effect that the left radial pulse was 102 and the right 96. He could not understand how, the heart being the prime cause of the circulation, the pulse-rate could be different on the two sides. He asked if the observation of the two pulses had been made at the same time. Mr. BARWELL thought the heart was not the sole cause of the pulse, and alluded to a case in which he had found the pulse-rate different on the two sides. Referring to Mr. Heath’s patient, he said that, as the arm had been paralysed, the aneurism must have passed as low as the pectoralis minor. Dr. PAvY thought that the cause of death in Mr. Fearn’s patient’s case might fairly be called an accidental one. If tilaments of the sympathetic or the vertebral artery be in- jured experimentally in animals, pleurisy is certainly pro- duced, and the extension of an aneurism would, by pressure on these filaments, produce a like result in man. Mr. HEATH, after thanking Mr. Holmes for the very hand- some way in which he had spoken of his case and the treat- ment pursued, remarked that Mr. Wardrop had only treated one case of innominate aneurism by the distal ligature, the other two cases being diagnosed quite correctly from the first as aneurisms of the lower part of the carotid. Only one of these latter caqes, however, was usually included in the list of operations, because in the other the carotid was found still pervious after death. He had not entered into details of other cases of innominate aneurism in his paper for fear of making it too lengthy ; but there was no question that, in all the cases at least in which two vessels had been tied, the diagnosis had been correctly established. Mr. Heath quite allowed that cases of innominate aneurism might go on for months under careful treatment, but it unfortunately happened that in most cases the disease made rapid progress and burst into the trachea or elsewhere. He alluded to the progress of Dr. Davies’ case and to two specimens which he had ex- hibited at the Pathological Society, in one of which the aneurism burst into the trachea, and in the other into the posterior triangle of the neck. With regard to the question of the pressure of the blood upon the sac after a distal liga- ture, Mr. Heath believed it to be impossible to give a decided answer. In the majority of cases the tumour immediately diminished (and notablv so in Wardron’s cases): but occa- sionally it increased. He was content to quote Broca’s own words, which are :-" I confess that I know no theory capable of explaining why Brasdor’s operation has the immediate effect of sometimes increasing and sometimes diminishing the size of the aneurism." With regard to the inequality of the pulses, Mr. Heath said he had no explanation to offer, but believed it to have been the fact, and the same difference was noticed when the pulse on the right side became perceptible after the operation. Mr. Fearn’s case hardly illustrated Dr. Pavy’s theory of pleurisy, which was no doubt a correct one, for the pleurisy in that case resulted from a direct injury to the ribs. Mr. SOLLY adverted to the age of the patient and to the traumatic origin of the aneurism-the patient had fallen out of a window. This would be a guide to the propriety of operations in future cases of aneurism. PATHOLOGICAL SOCIETY OF LONDON. TUESDAY, JAN. 1ST, 1867. ANNUAL REPORT. THE session of the Pathological Society (1865-66) has been marked by the steady advance in prosperity and usefulness which the condition of the Society’s affairs enabled the Council to pre- dict in presenting their last report. It was stated in that report that the number of annual subscriptions which had been received in the past year (303) was the largest which the Society had ever yet attained. In the present annual account, however, the receipt of 314 annual subscriptions is acknowledged, as well as two composition fees from resident members. The number of fees by admissions has also risen from 27 to 35. Thus it is seen that the number of the Society’s members con- tinues steadily on the increase. Nor will it be denied by those who have taken part in the session which has just terminated, that the activity and exer- tions of the working members of the Society in the prosecution of the object for which it was founded, is in proportion to its growth in numbers and reputation. The large expenditure which the Council have sanctioned on the seventeenth annual volume is, they hope, justified by the production of a volume not only much larger than its predecessors, but containing also a corresponding proportion of matter of permanent value and interest. It is perhaps a subject of regret that the expenses of a volume which, like this, shall be worthy of the reputation of the Pathological Society, should so nearly exhaust all the disposable funds. The Council have on this account taken into renewed consideration the possibility of obtaining a place of meeting without the great expense to which they are put for
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Page 1: PATHOLOGICAL SOCIETY OF LONDON. TUESDAY, JAN. 1ST, 1867

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In an appendix the author gave the details of M. P. Broca’s Iunpublished case of ligature of the subclavian artery for inno-minate aneurism, and also a table of the various cases of distalligature for aneurism of the root of the neck which have beenrecorded.Mr. HoLMES said that he was glad to have the opportunity

of bearing his testimony to the very gratifying success ob-tained in this case, which he thought Mr. Heath had accu-rately described as unique in the annals of surgery. He wishedto defend the accuracy of the views in his article on aneurismin the " System of Surgery" from the imputations which Mr.Heath appeared to cast upon them. In fact, however, Mr. !Heath, while saying that he "was somewhat in the dark" asto the proposals made for operation in these cases of supposedinnominate aneurism, had himself, in his subsequent remarks,completely vindicated the accuracy of the statement in the"System of Surgery." The operations proposed were reallyas there stated. First, the simultaneous ligature of the com-mon carotid and first part of the subclavian, as necessitatedby a logical following of the proposal known by Brasdor’sname, and as shown by Mr. Heath to have been practised inRossi’s operation. This operation Mr. Holmes had spoken ofas too dangerous to be justifiable, and Rossi’s case so far boreout that view. Secondly, the ligature of the carotid alone,which does not seem to hold out sufficient hope of success tojustify the risk to which it exposes the patient; and thirdly,the ligature of the carotid and third part of the subelanian.Before Mr. Heath’s case this double ligature had only beenpractised at a considerable interval of time between the twooperations, and Mr. Fearn’s was the only case in which successwas claimed ; but his account was obscurely worded, and ledMr. Holmes to doubt the reality of the cure. Mr. Fearn’spreparation now before the Society showed, however, that asfar as the disease in the innominate artery went it had beenarrested, and probably soundly cured, and the pressure uponthe trachea and threatened bursting into that tube obviated,so that the life of the patient was saved for the time. Butthe preparation also showed, as it seemed to him, that theaorta partook largely in the disease, and that, therefore, thoughlife had for the time been saved, the disease could not be saidin strictness to be cured. So in Mr. Heath’s case also. Hisaccount of the consultations prior to operation showed howgreat a doubt there was as to whether the aorta was or wasnot the seat of disease in this woman, and his perfectly Iaccurate and frank description of her present condition Ishowed also that the disease is far indeed from being cured,

’’

though its progress towards the trachea and towards thenervous cords forming the plexus had been arrested. Butit is well known that these tubular aneurisms or aneurismaldilatations involving the aorta, innominate, and perhaps alsosubclavian arteries, will go on sometimes for an indefinite

period without material alteration, and that the sacciform.dilatations or buds projecting out from them (like that in Mr.Fearn’s case) will sometimes, and perhaps not very infrequently,undergo spontaneous cure. Instances of these events werequoted from the recent practice of St. George’s Hospital.Considering, therefore, the great difficulty of diagnosis, therisk of finding the arteries diseased where exposed for opera-tion, the great likelihood of serious disease in the aorta or

even the heart also, and the possibility of spontaneous cure,or cure by appropriate regimen, it seems prudent not to under-take these operations without the gravest consideration, andin circumstances which can but rarely present themselves.Perhaps the best indication for operation would be the relativeamount of pressure on the trachea compared with that of thegeneral symptoms. That is, when the patient is otherwise inmoderately good health, but suffers much from dyspuaea, andappears likely to die soon from rupture of the aneurism inthis direction, the question of arresting it by ligature of thearteries of the right side might be considered, but in any caseit must be regarded rather as palliative than as curative. Mr.Holmes concluded by congratulating Mr. Heath on the successof an operation of such difficulty and magnitude, and whichreally appeared to have saved, or at least prolonged, thepatient’s life.

Mr. SAVORY referred to a remark in the report of the casewhich was to the effect that the left radial pulse was 102 andthe right 96. He could not understand how, the heart beingthe prime cause of the circulation, the pulse-rate could bedifferent on the two sides. He asked if the observation ofthe two pulses had been made at the same time.Mr. BARWELL thought the heart was not the sole cause of

the pulse, and alluded to a case in which he had found thepulse-rate different on the two sides. Referring to Mr.

Heath’s patient, he said that, as the arm had been paralysed,the aneurism must have passed as low as the pectoralis minor.Dr. PAvY thought that the cause of death in Mr. Fearn’s

patient’s case might fairly be called an accidental one. Iftilaments of the sympathetic or the vertebral artery be in-jured experimentally in animals, pleurisy is certainly pro-duced, and the extension of an aneurism would, by pressureon these filaments, produce a like result in man.Mr. HEATH, after thanking Mr. Holmes for the very hand-

some way in which he had spoken of his case and the treat-ment pursued, remarked that Mr. Wardrop had only treatedone case of innominate aneurism by the distal ligature, theother two cases being diagnosed quite correctly from the firstas aneurisms of the lower part of the carotid. Only one ofthese latter caqes, however, was usually included in the list ofoperations, because in the other the carotid was found stillpervious after death. He had not entered into details ofother cases of innominate aneurism in his paper for fear ofmaking it too lengthy ; but there was no question that, in allthe cases at least in which two vessels had been tied, thediagnosis had been correctly established. Mr. Heath quiteallowed that cases of innominate aneurism might go on formonths under careful treatment, but it unfortunately happenedthat in most cases the disease made rapid progress and burstinto the trachea or elsewhere. He alluded to the progress ofDr. Davies’ case and to two specimens which he had ex-hibited at the Pathological Society, in one of which theaneurism burst into the trachea, and in the other into theposterior triangle of the neck. With regard to the questionof the pressure of the blood upon the sac after a distal liga-ture, Mr. Heath believed it to be impossible to give a decidedanswer. In the majority of cases the tumour immediatelydiminished (and notablv so in Wardron’s cases): but occa-

sionally it increased. He was content to quote Broca’s ownwords, which are :-" I confess that I know no theory capableof explaining why Brasdor’s operation has the immediateeffect of sometimes increasing and sometimes diminishing thesize of the aneurism." With regard to the inequality of thepulses, Mr. Heath said he had no explanation to offer, butbelieved it to have been the fact, and the same difference wasnoticed when the pulse on the right side became perceptibleafter the operation. Mr. Fearn’s case hardly illustrated Dr.Pavy’s theory of pleurisy, which was no doubt a correct one,for the pleurisy in that case resulted from a direct injury tothe ribs.Mr. SOLLY adverted to the age of the patient and to the

traumatic origin of the aneurism-the patient had fallen outof a window. This would be a guide to the propriety ofoperations in future cases of aneurism.

PATHOLOGICAL SOCIETY OF LONDON.

TUESDAY, JAN. 1ST, 1867.

ANNUAL REPORT.

THE session of the Pathological Society (1865-66) has beenmarked by the steady advance in prosperity and usefulness whichthe condition of the Society’s affairs enabled the Council to pre-dict in presenting their last report. It was stated in that reportthat the number of annual subscriptions which had been receivedin the past year (303) was the largest which the Society hadever yet attained. In the present annual account, however,the receipt of 314 annual subscriptions is acknowledged, aswell as two composition fees from resident members. Thenumber of fees by admissions has also risen from 27 to 35.Thus it is seen that the number of the Society’s members con-tinues steadily on the increase. -

Nor will it be denied by those who have taken part in thesession which has just terminated, that the activity and exer-tions of the working members of the Society in the prosecutionof the object for which it was founded, is in proportion to itsgrowth in numbers and reputation. The large expenditurewhich the Council have sanctioned on the seventeenth annualvolume is, they hope, justified by the production of a volumenot only much larger than its predecessors, but containing alsoa corresponding proportion of matter of permanent value andinterest. It is perhaps a subject of regret that the expensesof a volume which, like this, shall be worthy of the reputationof the Pathological Society, should so nearly exhaust all thedisposable funds. The Council have on this account taken intorenewed consideration the possibility of obtaining a place ofmeeting without the great expense to which they are put for

Page 2: PATHOLOGICAL SOCIETY OF LONDON. TUESDAY, JAN. 1ST, 1867

14

the present rooms. They have accordingly drawn up and pre-sented to the Board of Works a petition for admission into therooms at Burlington House. As the accommodation whichthis Society requires can be afforded without displacing, or

even inconveniencing, any of the bodies at present lodged atBurlington House, the Council entertain a sanguine hope thatthe request may be granted.The alterations in the rules for exhibiting living specimens,

and the rule as to specimens which are not presented whencalled for in their turn, have been found to work well, andhave, it is hoped, quite remedied the slight inconvenienceswhich had been felt in former sessions. They have beenprinted on the yearly cards.Another topic which has lately been discussed by the Society,

and referred by them to the Council, is the appointment of acommittee to examine and report on all the specimens sub-mitted to the Society as being examples of "cancer." The

pressure of the necessary annual business at this period of thesession has prevented the Council from completing this matter,but they trust soon to be able to submit the names and regu-lations of this committee for the approval of the Society.In conclusion, the Council beg to hand in the treasurer’s

eport, of which the following is a summary :-The total income of the Society was £ 464 6s. 6d., and the

9xpenditure, £ 518 19s. 8d., exclusive of £ 100 invested in thefunds. The balance in hand at the commencement of the ses-sion was £ 122 198. ll2d., of which 9100 was thus invested, sothat there is at present due to the treasurer 931 13s. 22d. Theannual income is made up of the following items :-

The last item shows a very great increase on any previousyear.Thus it appears that the income of the Society, both from

subscriptions and investments, is increasing, and although theexpenditure this year has exceeded the income, it ought in fair-ness to be taken into account that this expenditure includes anitem of £30 for the printing and binding of fifty copies ofvolume xv., a volume which has a fair sale, and the printingof which may therefore be regarded as a remunerative invest-ment. The large expenditure on volume xvii., which hasamounted to £339 6s. 6d., will also, it is believed, prove re-munerative, for the Society now prints 500 copies instead of450, and is, therefore, in a position, so far as the three lastvolumes are concerned, to meet the numerous demands whichare constantly made for its publications. This being the casethe Council see no reason for discouragement, though thebalance of expenditure has for once been accidentally againstthe Society ; and if they succeed in getting quit of the greatcharge for rooms, they will be enabled to devote a still greaterproportion of the receipts to the legitimate purpose of im-

proving the yearly volume.

Reviews and Notices of Books.On Inhalation as a means of Local Treatment of the organs of

Respiration by Atomised Fluids and Gases. By HERMANNBEIGEL, M.D., L.R.C.P.L., Assistant-Physician to the

Metropolitan Free Hospital, &c. 8vo, pp. 200. London:Robert Hardwicke. 1866.

WE have heard a great deal lately of a science of inhalation.The great interest which was excited by the researches ofSales-Girons and others on the inhalation of atomised fluidshas stimulated numbers of practitioners to the cultivation ofwhat is termed in scientific slang "pneumatic medicine."

Dr. Beigel does not disguise his strong partiality for the ad-ministration of remedies by the way of the lungs; but he care-fully avoids any attempt to claim a universal application forit. A description has already appeared in our columns of themodifications of Siegle’s atomizer which Dr. Beigel uses, andwhich is very convenient as affording a screen that keeps thespray from the face and dress, and only allows it to enter themouth; and with the exception of a very convenient portable,or "traveller’s" atomizer, which he npw describes, there is

nothing requiring notice as regards the instruments he em-ploys.The drugs used by Dr. Beigel are as follows :-1. Nitrate

of silver, which is recommended for inflammatory conditionsof the pharynx and larynx. 2. Nitrate of aluminium (in-troduced by Dr. Beigel), which is said to be very useful innervous affections of the trachea and larynx. 3. Tannin is a

good astringent in some inflammatory states, especially inchronic catarrhs. 4. Alum acts in very much the same way.5. Sesquichloride of iron is a good styptic in hmmorrliages.6. Acetate of lead is sometimes useful in inveterate catarrh.7. Sulphate of zinc, which is used in small doses in chronic in-flammation of the air-passages, &c. 8. Common salt is usefulin a large number of cases, but is especially beneficial in all’stages of phthisis. 9. Tincture of opium, which has long beenwell known as a lung-medicine of good efficacy. 10. Liquorarsenicalis, a very useful remedy for asthma. 11. Pure water,cold or warm, or even as hot as the patient can bear it, some-times does much good in inflammation or in paralysis of thelarynx. 12. Glycerine (recommended by Demarquay), as

soothing the inflammatory irritation of the pharynx, and todestroy the fetor of some diseases of the pharynx and palate,and recommended also by Scott Alison in laryngitis and tra-cheitis, with hoarseness or loss of voice. 13 Lime-water, re-commended as a solvent of diphtheric membranes. 14. Finally,Dr. Beigel makes the surprising assertion, that (with somemodifications of his instrument) cod-liver oil can be more effec-tually and beneficially given by the lungs than by the stomach !As for the mechanical possibility, surprising as it is, we canhardly dispute it in face of Dr. Beigel’s direct experience; butwe should greatly doubt the comparative advantage of the plan.However, the mere fact that so apparently intractable a sub-stance can be inhaled at all is a proof that the atomising pro-cess has gone a long way already.

Besides atomised fluids, Dr. Beigel refers to his employmentof volatile chemicals and gases. We must say that we thinkhe does some injustice to the value of the former, which cer-tainly yield very reliable results when used in appropriate dis-eases. On the other hand, he takes up the oxygen controversydecidedly as a partisan of the medicinal value of that gas.He does not, indeed, make nonsensical statements about itspower to cure phthisis. But he assigns it a real value in re-

lieving some of the distressing symptoms of asthma, of ad-vanced consumption, chronic bronchitis, anaemia, Bright’s dis-ease, and chlorosis. He regards it as decidedcoratra-indicatedin inflammatory conditions. We do not expect that practi-tioners generally will assent to Dr. Beigel’s high estimate of £

oxygen; still he is no doubt supported to some extent by therecent observations of Demarquay and others, and it is desir-able that a fair hearing should be given to his opinion. It isinstructive to note that Professor Trousseau’s judgment of theeffects of oxygen inhalations in tuberculosis (under the skilfulhands of Demarquay) is decidedly unfavourable.

Altogether the work is deserving of the perusal of all prac-titioners, and will, doubtless, help to make the professionfamiliar with a very important auxiliary mode of treatment.Dr. Beigel is entitled to the credit of having helped much tosimplify the process and instruments of inhalation, so as toput it within the reach of all medical men, and of all but thepoorest patients.

OUR LIBRARY TABLE.

The Student’s Text-book of Electricity. By HENRY M. NOAD,Ph.D., F. 11. S., F.C.S., Lecturer on Chemistry at St. George’sHospital, &c. Small 8vo. pp. 519. London : Lockwood andCo. 1867.-Clear, compendious, compact, well-illustrated,and well-printed, this is an excellent manual. Both theoreti-

cally and practically it brings the student as well abreast ofthe advanced electrical knowledge of the day as is compatiblewith a text-book. Where all is good and carefully written it


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