Pathology

Pathology Course Haematology 1

Kindly sponsored by:EXAM TIPSMAKE YOUR PATH NOTES NOW!REPETITION REPETITION REPETITIONDONT GET BOGGED DOWN in THE DETAILHAEMATOLOGY SESSIONS- listen! Dont make notes- max efficiency learning of CORE KNOWLEDGE- add details later- BSH revision day SESSION 1- ANIKA- ANAEMIAS AND CLOTTINGSESSION 2- SARNEET- LYPHOMAS AND LEUKAEMIAS

AND in terms of LOW/NORMAL/HIGH MCV

- Third heart soundLow MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)Pregnancy

Low MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)PregnancyLow MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)PregnancyLow MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)Pregnancy

Low MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)PregnancyLow MCV (microcytic anaemia) (FAST)Normal MCV (normocytic anaemia)High MCV (macrocytic anaemia)Fe-deficiency anaemiaAcute blood lossB12 or folate deficiencyAnaemia of chronic disease Anaemia of chronic diseaseAlcohol excess or liver diseaseSideroblastic anaemiaBone marrow failureReticulocytosis (e.g. with haemolysis)Thalassaemia (in the absence of anaemia)Renal failureMyelodysplastic syndromesHypothyroidismHypothyroidismHaemolysis Antifolate drugs (e.g. phenytoin)Pregnancy

ClassificationCausesDiscussion Blood lossGastrointestinal loss

PV lossMeckels diverticulum (older children)Peptic ulcers (adult men) / Gastritis (chronic NSAID use)Hookworm infestation (developing countries)Polyps/colorectal Ca (most common cause in adults >50yrs)Menorrhagia (women