PATHOLOGY OF KIDNEYS

VIII. practical training

3rd year General Medicine

Infantile cystosis (Microcystosis) of kidneys

Vascular nephrosclerosis

Vascular nephrosclerosis

Classification of glomerular diseases

Primary Glomerular Diseases

Glomerulonefritis in Systemic Diseases

Glomerular Lesions in Vascular Diseases

Glomerular Lesions in Metabolic Diseases

Hereditary Nephropathies

Miscellaneous Glomerular Diseases

End Stage Kidney

Glomerular Lesions Following Transplantation

Diabetic glomerulosclerosis (Kimmelstiel-Wilson)

1 hyaline deposits in mesangial

matrix of glomerulus

1

Diabetic glomerulosclerosis

(Kimmelstiel-Wilson)

Diabetic glomerulosclerosis (Kimmelstiel-Wilson)

1 hyaline globules in mesangial

matrix of glomerulus

2 capillaries around hyaline

globules

3 hyalinosis of mesangium

1

2 3

Armani’s cells (PAS)

Non-suppurative interstitial nephritis

Endocapillary proliferative glomerulonefritis

1 Reduction of capillary lumen

2 Bulge and proliferation of cellular

formation of glomerulus

1

2

2

2

Endocapillary proliferative glomerulonefritis

immunoflourescenc-subendothelial immune-complex deposit

1

1 Granular subendothelial

deposits on basal membrane

E Swelling endothelial cells

1 Basal membrane

Stars- subendothelial deposits of

immunoglobulins on basal

membrane

1

Endocapillary proliferative glomerulonefritis, electronogram

Chronic glomerulonefritis

Chronic glomerulonefritis

Rapidly progressive (crescentic) glomerulonephritis

1 Extracapillary proliferation of

epithelial cells of Bowman capsule

and fibrin – compression of

glomerular capillaries

2 Regresive alteration of glomerular

capillaries

1

2

2

Rapidly progressive (crescentic) glomerulonephritis

1 Basal membrane of Bowman

capsule

2 Fibrin

3 Hyaline deposits in glomerular

capillaries

1

2

3

3

3

Acute suppurative pyelonephritis

Acute suppurative pyelonephritis

Acute suppurative pyelonephritis

Chronic pyelonefritis (end stage kidney, anamnesis of

prostatic hypertrophy)

Dilatated ureter

Capsule of kidney

End stage kidney

Kidney without big changes

Chronic urocystitis

Amyloid nephropathy

Amyloid nephropathy

Biliary nephrosis

Chronic hydronephrosis

Chronic hydronephrosis

Wilms’ tumour (nephroblastoma)

Wilms’ tumour (nephroblastoma)

1 1 Stromal component

2 Blastema component

3 Epithelial component

1

2

2

3

Nephroblastoma

Renal cell carcinoma, conventional type

tumour

Lower pole of

kidney

Kidney in

section

Tumour

invasion

inside vein

in hilus

Renal cell carcinoma, clear cell type

Renal cell carcinoma, clear cell type