PATHOLOGY OF THE SKIN.

PERINATAL PATHOLOGY,

PATHOLOGY OF THE

NEWBORN AND INFANT

XIII. practical training

3rd year General Medicine

Inflammatory dermatosis

Spongiotic dermatosis

Psoriasiform dermatosis

Vesiculobulous dermatosis

Cytotoxic dermatosis

Angiocentric dermatosis

Granulocytic dermatosis

Granulomatous dermatosis

Paniculitis

Spongiotic dermatitis (subacute eczema dermatitis)

Psoriasis

Chronic course of disease (hyperproliferation of epidermis)

Hyperkeratosis

Parakeratosis

Papillomatosis

Neutrophils in stratum corneum

Different forms:

papules, plaques, erythrodermia,

alteration of nails, hyperpigmentation

General symptoms, arthropathy

Psoriasis

Psoriasis,

erythroderma

Psoriasis

Psoriasis

Psoriasis

Psoriasis

guttata

Psoriasis, chronic alteration of nails

Psoriasis palmaris (palmoplantaris)

Psoriasis

1

1

2

2

3

1 acanthosis

2 compact hyperkeratosis

with parakeratosis

3 stratum granulosum is absent

Psoriasis, microabscessus of

Munro´s (residues of neutrophil leukocytes in stratum corneum)

parakeratotic lamellae

with neutrophil residues

Psoriasis pustulosa palmoplantaris

intraepidermal pustule, acanthosis

TBC, Lupus vulgaris

TBC, Lupus vulgaris

TBC, Lupus vulgaris, TBC verrucosa

tuberculous granulomas with

multiple Langhan’s cells

Atheroma of the skin with inflammatory and giant cell reaction

Verruca vulgaris

Verruca vulgaris

Verruca vulgaris

1

2

3

1 hyperkeratosis

2 papilomatosis

3 parakeratosis

Verruca vulgaris

1

1 parakeratosis

Molluscum contagiosum

Molluscum contagiosum

Seborrheic keratosis (verruca)

Seborrheic keratosis (verruca)

Seborrheic keratosis (verruca)

1 2

1 hinges of proliferating basaloid cells, 2 abruptive keratosis

Seborrheic keratosis (verruca)

1 proliferating basaloid cells, melanin

2 abruptive keratosis

Bowen’s dermatosis

Bowen’s dermatosis

dysplastic, polymorphic keratinocytes (spread in adnexal epithelium)

Bowen’s dermatosis

dysplastic, polymorphic keratinocytes in groups

Bowen’s dermatosis

acanthosis,

hyperkeratosis with parakeratosis

Squamous cell carcinoma

Keratinizing squamous cell carcinoma

Keratinizing squamous cell carcinoma

1

2

1 tumour infiltration, 2 hyperkeratosis, acanthosis

Keratinizing squamous cell carcinoma

1

2

2

2

1 keratinization in tumour hinge, 2 mitosis

Basal cell carcinoma (Basalioma)

Basal cell carcinoma

Basal cell carcinoma

Basalioma terebrans

Basal cell carcinoma

Hinges of basaloid tumour epithelium, pigmentation (melanin)

1 fissure between tumour epithelium and fibrous stroma of

corium

1

Basal cell carcinoma

1

2

1 tumour hinges

2 pigment

Basal cell carcinoma

1 fissure between tumour epithelium and

fibrous stroma of corium 1

Basal cell carcinoma with pigment

Basal cell carcinoma, superficial

multiple focuses

lymphocytic infiltrate

in base

Basal cell carcinoma, infiltrating (morphea type)

1

2

1 infiltrating tumour hinges, 2 sclerotic fibrous tissue

3 inflammatory infiltrate

3

1

1

Junctional nevocellular nevus

Intradermal nevocellular nevus

Malignant melanoma

Malignant melanoma

Malignant melanoma

Malignant melanoma

Aspiration of amniotic fluid

Respiratory distress syndrome – hyaline membranes

Hyaline membranes

1 Undeveloped alveoli

2 Hyaline membranes

1 2

1

1

2

2

Hyaline membranes

1 Hyaline membranes

1

1

1

1

Respiratory distress syndrome – acute catarrhal

bronchopneumonia