PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Patient-Centered Outcomes Research InstituteExecutive Director’s Welcome
PCORI Board of Governors MeetingWashington, DCSeptember 24, 2012
Joe V. Selby, MD, MPH, Executive Director
PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
New PCORI Staff – since May 2012
Kara Odom-WalkerScientistAugust 13, 2012
Katie WilsonProject AssociateJune 11, 2012
Orlando GonzalesChief of StaffAugust 1, 2012
Michele OrzaSenior Advisor to the Executive DirectorSeptember 4, 2012
Gregory MartinDeputy Director, Stakeholder EngagementJuly 23, 2012
James HulbertContracts AdministratorSeptember 10, 2012
Marla BolotskyAssociate Director, Digital MediaSeptember 5, 2012
Ayodola AniseProject AssociateAugust 13, 2012
Kelton ChapmanAssistant Manager, Meetings and Special EventsMay 29, 2012
Not Shown: Lorraine Bell, Senior Program Associate – May 29, 2012Desiree Frank, Executive Assistant to the Executive Director – June 19, 2012Kimberly Holloway, Senior Administrative Assistant – August 27, 2012David Hickam, Scientific Program Leader, Health System Research – September 17, 2012Jordan Elliker, Project Events Coordinator – September 19, 2012
PCORI PILOT PROJECTS (PPP)• 50 projects funded (of 856); mostly 2-years in length• $31 million total funding
PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Funded PCORI Pilot Projects in 25 States and DC
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
PCORI Pilot Projects Areas of Interest
Area of Interest Submitted FundedInforming PCORI national priorities 21 2Bringing together patients, caregivers, and other stakeholders in all stages of a research process 80 1Translating evidence into health care practice in ways that account for individual patient preferences for various outcomes, including decision-support tools 180 19Collecting and assessing patient- and provider-perceived gaps in evidence 26 0Identifying, testing, and/or evaluating patient-centered outcomes instruments 214 11Assessing the patient perspective when researching behaviors, lifestyles, and choices 31 5Studying patient care team interactions in situations where multiple options exist 45 6Analytical methods for CER 170 6
PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Types of Organization
Primes
Subcontractors
Overview: All Applications
Type Primes Subs FundedAcademic 561 235 38Hospitals 80 98 4Research organizations 55 49 3Non-profit health systems 28 54 2
Community-based health centers 20 46 0
Consultants 18 32 1Provider associations 16 19 0Patient associations 10 40 1Non-profit foundations 9 24 1Technology organizations 7 25 0Government 5 16 0For-profit health benefits 2 0 0For-profit pharmaceutical 1 2 0Other 0 52 0 6
PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Target Populations – Applicants & Awardees
Underserv
ed
Speci
fic Ethnic o
r Cultu
ral
Disabled
Urban & Rural
Only Urban
Only Rural
Unspecified-10%
0%10%20%30%40%50%60%
Percent of Total Applications Total Applications by Target Population
Population All Funded
Underserved 453 30
Specific Ethnic or Cultural 243 21
Disabled 163 12
Urban & Rural 383 28
Only Urban 188 14
Only Rural 22 1
Unspecified 224 8
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Monitoring the Pilot Projects
Two-year competitive contract awarded to AcademyHealth (A Rein, PI) to do the following:
Work closely with PCORI to monitor the 50 pilot projects for achievement of specific aims
Assess learnings on patient engagement in research from all 50 projects
Identify 5 subgroups with common themes, convene and create joint products within each thematic area
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PCORI FUNDING ANNOUNCEMENT APPLICATIONS• 483 applications received• Review process underway• ~ 100 awards expected in December 2012
PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Description of Applications Received
Top 15 States Applying
483 applications received
Applications by PFA
71; 15%
211; 44%92; 19%
109; 23%
Addressing DisparitiesAssessment of Prevention, Diagnosis, and Treatment OptionsCommunication and Dissemination ResearchImproving Healthcare Systems
CAPA
MANY
MNTX
WAFL
NCMDMIIL
GAOH
IA
0 10 20 30 40 50 60
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Mention of Specific Conditions
Multiple conditions and study designs may be noted in a single application.
Chronic C
onditionsOther
Cancer
Diabete
s
Cardiac
Health
Mental
Health
Acute Care
Pain
Vascular
Health
Rare Dise
ase
Substa
nce Dise
ase
Motor Reh
abilit
ation
Blood Disord
ers
Autism0
50
100
150
200
250
300
Num
ber o
f App
licati
ons
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Study Designs Noted in Applications
Evidence
Synthesis
Mixed M
ethods
Modeling St
udyOther
Prospective
Observa
tional (nonrandomize
d)
Prospective
Observa
tional (randomize
d)
Qualitative
Study
Random Control T
rial
Seco
ndary Data Analys
is0
10
20
30
40
50
60
70
80
90
Priority #1: Assessment of Prevention, Diagnosis, and Treatment Options (n=211 applications)
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Disabled Persons
Elderly Other Pediatric Racial or Ethnic Group
Rural Urban Veterans Women0
10
20
30
40
50
60
70
80
Priority #1: Assessment of Prevention, Diagnosis, and Treatment Options (n=211 applications)
Study Populations Noted in ApplicationsN
umbe
r of A
pplic
ation
s
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Reviewers
Volunteers TotalApplicants
First Round
Second Round
Technical Reviewers 800+ 483* 75-100
Patient Reviewers 225 -- 25
Stakeholder Reviewers 225 25
Committee Chairs -- 10
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
PCORI’s 8 Review Criteria
1. Impact of the Condition2. Innovation and Potential for Improvement3. Impact on Healthcare Performance4. Patient-Centeredness5. Rigorous Research Methods6. Inclusiveness of Different Populations7. Team and Environment8. Efficient Use of Resources
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
Agenda for Today’s Meeting
Patient and Stakeholder EngagementPrioritization of Research TopicsAdvisory PanelsConflict of Interest Policy and Plan for Methodology CommitteePCORI Funding Announcement 5A - MethodsMethodology Committee Public Comment 2012 BudgetCommunications Update
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PAT IE N T- C E N T E R ED O U TC O ME S R E SE A RC H I N ST IT U T E
• Appendix A: PICORI Pilot Projects Update
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Appendix
