7/25/2019 Pb Poisoning

1/16

7/25/2019 Pb Poisoning

2/16

CASE SCENARIOAn 18-month-old child of migrant farm workers washospitalized because of weight loss, vomiting, andacute abdominal pain. It was noted that the cildhad mild muscular incoordination and weakness ofthe muscles of the feet.

A blood smear showed a moderate but distinctincrease in the reticulocyte count.

7/25/2019 Pb Poisoning

3/16

Patients Data

Age 18 months! "eight #oss $omiting%Acute Abdominal &ain%'ild 'uscular Incoordination% "eakness of the muscles of the feet

7/25/2019 Pb Poisoning

4/16

Laboratory Tests & Normal Va

Patients FIndings Normal Value(ed )lood *ell *ount 4 X 10 6 cells/ mm 3 Age 'ale

+emale

ewborns . -/./ 'onths- y.o. .1-/.2 -1 y.o. .2- .3

.31 -18y.o. . -/.0

.3418y.o 0.8-/. /.8

5ematocrit 37% Age 'ale6 6

ewborns 0. -/ .1 //.3

7/25/2019 Pb Poisoning

5/16

rinalysis -5our rine!

- 6.4 umol (840 ug) of Aminolevulinic acid- 1.8 umol (1. mg) of !o"#o"o#"$ #in &&&- 1.1 umol (0. 4 mg) of lead

7/25/2019 Pb Poisoning

6/16

What is Lea Poisonin!" #ead poisoning occurs when lead builds up in the body, often over a

period of months or years. 9ven small amounts of lead can causeserious health problems. *hildren under the age of are especiallyvulnerable to lead poisoning, which can severely a:ect mental andphysical development. At very high levels, lead poisoning can befatal.

#ead-based paint and lead-contaminated dust in older buildings arethe most common sources of lead poisoning in children. ;ther sourcesinclude contaminated air, water and soil. Adults who work withbatteries, do home renovations or work in auto repair shops also maybe e

7/25/2019 Pb Poisoning

7/16

7/25/2019 Pb Poisoning

8/16

Si!ns an Sym#toms

7/25/2019 Pb Poisoning

9/16

Si!ns an Sym#toms

7/25/2019 Pb Poisoning

10/16

Causes #ead in &aint Ingestion!

"ater pipes soldered with lead! and imported cannedgoods solder! =raditional remedies

7/25/2019 Pb Poisoning

11/16

Causes

7/25/2019 Pb Poisoning

12/16

Ris$ %a tors

7/25/2019 Pb Poisoning

13/16

7/25/2019 Pb Poisoning

14/16

Com#li ations

7/25/2019 Pb Poisoning

15/16

Treatment (emove the source of contamination Chelation thera#y % In this treatment, you take medication

that binds with the lead so that it>s e

7/25/2019 Pb Poisoning

16/16

Pre)ention