contact

PD Dr. Jan Borovicka

titel PD Dr. med

first name Jan

last name Borovicka

street Rorschacherstrasse 95

city 9007 St. Gallen

country Switzerland

phone number 071 494 26 46

mobile number 078 653 55 99

fax 071 494 63 27

e-mail jan.borovicka@kssg

homepage www.gastro-kssg.ch

2

publications

title

journalpaper/review

Müller-Stich B P, Linke G R, Senft J, Achtstätter V, Müller P C, Diener M K,Warschkow R, Marra F, Schmied B M, Borovicka J, Fischer L, Zerz A, GuttC N, Büchler M W. Laparoscopic Mesh-augmented Hiatoplasty WithCardiophrenicopexy Versus Laparoscopic Nissen Fundoplication for theTreatment of Gastroesophageal Reflux Disease: A Double-centerRandomized Controlled Trial. Ann Surg 2015; 262:721-7.

Sawatzki M, Borovicka J, Meyenberger C, Frei R. Stenting after severeiatrogenic submucosal. Gastrointestinal Endoscopy 2015;1499-1501.

Krieger-Grübel C, Tutuian R, Borovicka J. Correlation of esophagealclearance and dysphagia symptom assessment after treatment forachalasia. United European Gastroenterology Journal 2015; 0:1-7.

Sawatzki M, Brunner W, Neff-Schöb A, Meyenberger C, Borovicka J.Chronische Nausea und Emesis. Swiss Medical Forum 2015;15:1039-1040.

Sulz M, Frei R, Semadeni G M, Sawatzki M, Borovicka J, Meyenberger C.The role of single-balloon colonoscopy for patients with previousincomplete standard colonoscopy: Is it worth doing it?. Surg Endosc2015;.

Sulz M, Bertolini R, Frei R, Semadeni G M, Borovicka J, Meyenberger C.Multipurpose use of the Over-the-Scope-Clip system (‘Bear claw’) in thegastrointestinal tract: Swiss experience in a tertiary center. World Journalof Gastroenterology 2014; 20: .:16287-16292.

Sawatzki M, Meyenberger C, Borovicka J. New Kit on the block -unkonventionelle Hemopray-Anwendung. Swiss Medical Forum 2014;14:734-735.

3

publications

title

journalpaper/review

Preissler C, Krieger-Grübel C, Borovicka J, Fried M, Tutuian R. Thecontribution of intrabolus pressure to symptoms induced by gastricbanding. J Gastrointestin Liver Dis 2014; 23:13-7.

Tack J, Zerbib F, Blondeau K, des Varannes S B, Piessevaux H, BorovickaJ, Mion F, Fox M, Bredenoord A J, Louis H, Dedrie S, Hoppenbrouwers M,Meulemans A, Rykx A, Thielemans L, Ruth M. Randomized clinical trial:effect of the 5-HT4 receptor agonist revexepride on reflux parameters inpatients with persistent reflux symptoms despite PPI treatment.Neurogastroenterol Motil 2014; 27:258-68.

Sulz M, Bertolini R, Frei R, Semadeni G M, Borovicka J, Meyenberger C.Multipurpose use of the over-the-scope-clip system ("Bear claw") in thegastrointestinal tract: Swiss experience in a tertiary center. World JGastroenterol 2014; 20:16287-92.

Stickel F, Worni M, Pache I, Moradpour D, Helbling B, Borovicka J, GerlachT J. Optimizing ribavirin exposure by therapeutic drug monitoringimproves treatment response in patients with chronic hepatitis Cgenotype 1. Am J Gastroenterol 2013; 108:1176-8.

Putora P M, Müller J, Borovicka J, Plasswilm L, Schmidt F. Relevance ofincidental colorectal FDG-PET/CT-enhanced lesions. Onkologie 2013;36:200-4.

Sulz M, Sagmeister M, Schelling M, Binek J, Borovicka J, Ulmer H,Meyenberger C. Quality assurance of sphincterotomy: A prospectivesingle-center survey. Central European Journal of European Medicine2012; 7:9-19.

4

publications

title

journalpaper/review

Häuptle R, Weilenmann D, Schneider T, Haile S, Ammann P, Knellwolf C,Borovicka J. Individualised PPI prescription in patients on combinationantiplatelet therapy and upper gastrointestinal events after percutaneouscoronary intervention: a cohort study. Wien Med Wochenschr 2012;162:67-73.

Borovicka J, Meyenberger C, Anliker M D, Stöckli S, Bühler D. Toxischeepidermale Nekrolyse: Therapie einer kompletten hypopharyngealenOkklusion bei toxischer epidermaler Nekrolyse (Lyell-Syndrom); eininterdisziplinärer Approach. Schweiz Med Forum 2011; 11:593-594.

Roushan A H, Wolff K T, Beutner U, Borovicka J, Marti L. Functionaloutcome after perineal stapled prolapse resection for external rectalprolapse. BMC Surg 2010; 10:9.

Lindenmann N, Meyenberger C, Hell M, Ulmer H, Spieler P, Borovicka J.Malignant biliary stenosis: conventional cytology versus DNA imagecytometry. Surg Endosc 2010;.

Gonvers J J, Heim M H, Cavassini M, Müllhaupt B, Genné D, Bernasconi E,Borovicka J, Cerny A, Chave J P, Chuard C, Dufour F, Dutoit V, MalinverniR, Monnat M, Negro F, Troilliet N, Oneta C. Treatment of hepatitis C inHCV mono-infected and in HIV-HCV co-infected patients: an open-labelled comparison study. Swiss Med Wkly 2010; 140:w13055.

Overbeck K, Dufour J F, Müllhaupt B, Helbling B, Borovicka J, MalinverniR, Heim M, Moradpur D, Cerny A, Rickenbach M, Negro F. Impact ofinternational consensus guidelines on antiviral therapy of chronichepatitis C patients in Switzerland. Swiss Med Wkly 2010;.

5

publications

title

journalpaper/review

Rauch A, Kutalik Z, Descombes P, Cai T, Di Iulio J, Mueller T, Bochud M,Battegay M, Bernasconi E, Borovicka J, Colombo S, Cerny A, Dufour J F,Furrer H, Günthard H F, Heim M, Hirschel B, Malinverni R, Moradpour D,Müllhaupt B, Beckmann J S, Berg T, Bergmann S, Negro F, Telenti A,Bochud P Y, Swiss Hepatitis C Cohort Study , Swiss HIV Cohort Study .Genetic variation in IL28B is associated with chronic hepatitis C andtreatment failure: a genome-wide association study. Gastroenterology2010; 138:1338-45, 1345.e1-7.

Bochud P Y, Cai T, Overbeck K, Bochud M, Dufour J F, Müllhaupt B,Borovicka J, Heim M, Moradpour D, Cerny A, Malinverni R, Francioli P,Negro F, Swiss Hepatitis C Cohort Study Group . Genotype 3 is associatedwith accelerated fibrosis progression in chronic hepatitis C. Journal ofhepatology 2009; 51:655-66.

Vogt N, Schönegg R, Gschossmann J M, Borovicka J. Benefit of baselinecytometry for surveillance of patients with Barrett's esophagus. Surgicalendoscopy 2009;.

Borovicka J, Schönegg R, Hell M, Kradolfer D, Bauerfeind P, Dorta G,Netzer P, Meyenberger C, Fischer J E, Spieler P. Is there an advantage tobe gained from adding digital image cytometry of brush cytology to astandard biopsy protocol in patients with Barrett's esophagus?.Endoscopy 2009; 41:409-14.

Boller D, Spieler P, Schönegg R, Neuweiler J, Kradolfer D, Studer R,Grossenbacher R, Meyenberger C, Borovicka J. Lugol chromoendoscopycombined with brush cytology in patients at risk for esophagealsquamous cell carcinoma. Surgical endoscopy 2009;.

Grübel C, Borovicka J, Schwizer W, Fox M, Hebbard G. Diffuse esophagealspasm. The American journal of gastroenterology 2008; 103:450-7.

6

publications

title

journalpaper/review

Linke G R, Borovicka J, Schneider P, Zerz A, Warschkow R, Müller-Stich BP. Is a barium swallow complementary to endoscopy essential in thepreoperative assessment of laparoscopic antireflux and hiatal herniasurgery?. Surgical endoscopy 2008; 22:96-100.

Helbling B, Overbeck K, Gonvers J J, Malinverni R, Dufour J F, BorovickaJ, Heim M, Cerny A, Negro F, Bucher S, Rickenbach M, Renner E L,Mullhaupt B, Swiss Hepatitis C Cohort Study . Host- rather than virus-related factors reduce health-related quality of life in hepatitis C virusinfection. Gut 2008; 57:1597-603.

Ciuffreda D, Comte D, Cavassini M, Giostra E, Bühler L, Perruchoud M,Heim M H, Battegay M, Genné D, Mulhaupt B, Malinverni R, Oneta C,Bernasconi E, Monnat M, Cerny A, Chuard C, Borovicka J, Mentha G,Pascual M, Gonvers J J, Pantaleo G, Dutoit V. Polyfunctional HCV-specificT-cell responses are associated with effective control of HCV replication.European journal of immunology 2008; 38:2665-77.

Müller-Stich B P, Linke G R, Borovicka J, Marra F, Warschkow R, MehrabiA, Köninger J, Gutt C N, Zerz A. Laparoscopic mesh-augmentedhiatoplasty as a treatment of gastroesophageal reflux disease and hiatalhernias-preliminary clinical and functional results of a prospective caseseries. American journal of surgery 2008; 195:749-56.

Jeske H C, Borovicka J, von Goedecke A, Tiefenthaler W, Hohlrieder M,Heidegger T, Benzer A. Preoperative administration of esomeprazole hasno influence on frequency of refluxes. Journal of clinical anesthesia 2008;20:191-5.

Schwab C, Borovicka J, Schmid H P, Engeler D. [Urethral fistula due toCrohn's disease: case report of successful conservative management].Der Urologe. Ausg. A 2008; 47:1350-2.

7

publications

title

journalpaper/review

Borovicka J. Efficacy of laparoscopic mesh-augmented hiatoplasty inGERD and symptomatic hiatal hernia. Study using combined impedance-pH monitoring. J Gastrointest Surg 2008; 12:816-21.

Linke G R, Zerz A, Tutuian R, Marra F, Warschkow R, Müller-Stich B P,Borovicka J. Efficacy of laparoscopic mesh-augmented hiatoplasty inGERD and symptomatic hiatal hernia. Study using combined impedance-pH monitoring. Journal of gastrointestinal surgery : official journal of theSociety for Surgery of the Alimentary Tract 2008; 12:816-21.

Borovicka J. Laparoscopic mesh-augmented hiatoplasty as a treatment ofgastroesophageal reflux disease and hiatal hernias-preliminary clinicaland functional results of a prospective case series. Am J Surg 2008;195:749-56.

Borovicka J. Laparoscopic mesh-augmented hiatoplasty as a treatment ofgastroesophageal reflux disease and hiatal hernias-preliminary clinicaland functional results of a prospective case series. Am J Surg 2008;195:749-56.

Borovicka J. Efficacy of laparoscopic mesh-augmented hiatoplasty inGERD and symptomatic hiatal hernia. Study using combined impedance-pH monitoring. J Gastrointest Surg 2008; 12:816-21.

Linke G, Zerz A, Tutuian R, Marra F, Warschkow R, Müller-Stich B,Borovicka J. Efficacy of laparoscopic mesh-augmented hiatoplasty inGERD and symptomatic hiatal hernia. Study using combined impedance-pH monitoring. J Gastrointest Surg 2008; 12:816-821.

Müller-Stich B, Linke G, Borovicka J, Marra F, Warschkow R, Mehrabi A,Köninger J, Gutt C, Zerz A. Laparoscopic mesh-augmented hiatoplasty asa treatment of gastroesophageal reflux disease and hiatal hernias-preliminary clinical and functional results of a prospective case series. AmJ Surg 2008; 195:749-756.

8

publications

title

journalpaper/review

Linke G R, Borovicka J, Tutuian R, Warschkow R, Zerz A, Zünd M. Alteredesophageal motility and gastroesophageal barrier in patients with jejunalinterposition after distal esophageal resection for early stageadenocarcinoma. Journal of gastrointestinal surgery : official journal ofthe Society for Surgery of the Alimentary Tract 2007; 11:1262-7.

Gruebel C, Linke G, Tutuian R, Hebbard G, Zerz A, Meyenberger C,Borovicka J. Prospective study examining the impact of multichannelintraluminal impedance on antireflux surgery. Surg Endosc 2007;22:1241-7.

Helbling B, Jochum W, Stamenic I, Knöpfli M, Cerny A, Borovicka J,Gonvers J J, Wilhelmi M, Dinges S, Müllhaupt B, Esteban A, Meyer-WyssB, Renner E L, Swiss Association for the Study of the Liver (SASL) . HCV-related advanced fibrosis/cirrhosis: randomized controlled trial ofpegylated interferon alpha-2a and ribavirin. Journal of viral hepatitis2006; 13:762-9.

Meyer-Wyss B, Rich P, Egger H, Helbling B, Müllhaupt B, Rammert C,Gonvers J J, Oneta C, Criblez D, Rossi L, Borovicka J, Meyenberger C, ArnM, Renner E L, Swiss Association for the Study of the Liver (SASL) .Comparison of two PEG-interferon alpha-2b doses (1.0 or 1.5 microg/kg)combined with ribavirin in interferon-naïve patients with chronic hepatitisC and up to moderate fibrosis. Journal of viral hepatitis 2006; 13:457-65.

Borovicka J, Fischer J, Neuweiler J, Netzer P, Gschossmann J, Ehmann T,Bauerfeind P, Dorta G, Meyenberger C. Autofluorescence endoscopy insurveillance of Barrett's esophagus: a multicenter randomized trial ondiagnostic efficacy. Endoscopy 2006; 38:867-72.

. Helicobacter pylori 2006: How to test, when to treat. Schweiz RundschMed Prax. 2006; 95:1413-1418.

9

publications

title

journalpaper/review

van der Weg B, Meyenberger C, Borovicka J. helicobacter pylori: Wanntesten, wie testen?. Hausarztpraxis 2006;.

van der Weg B, Meyenberger C, Borovicka J. [Helicobacter pylori 2006:how to test, when to treat]. Praxis 2006; 95:1413-8.

Jeske H C, Borovicka J, von Goedecke A, Meyenberger C, Heidegger T,Benzer A. The influence of postural changes on gastroesophageal refluxand barrier pressure in nonfasting individuals. Anesthesia and analgesia2005; 101:597-600, table of contents.

Hurschler D, Borovicka J, Neuweiler J, Öhlschlegel C, Sagmeister M,Meyenberger C, Schmid U. Increased detection rates of Barrett'soesophagus without rise in incidence of oesophageal adenocarcinoma.Swiss medical weekly : official journal of the Swiss Society of InfectiousDiseases, the Swiss Society of Internal Medicine, the Swiss Society ofPneumology 2003; 133:507-14.

August-Jörg B S E, Borovicka J, Dufour J F, Gonvers J J, Henz S, HermannR, Meyenberger C, Weitz M, Renner E L, Swiss Association for the Studyof the Liver . Twenty-four vs. forty-eight weeks of re-therapy withinterferon alpha 2b and ribavirin in interferon alpha monotherapyrelapsers with chronic hepatitis C. Swiss medical weekly : official journalof the Swiss Society of Infectious Diseases, the Swiss Society of InternalMedicine, the Swiss Society of Pneumology 2003; 133:455-60.

Gubler C, Borovicka J, Diener P A, Meyenberger C. CholestatischeHepatitis. Schweiz. Rundsch. Med. Prax. 2003; 92:1269-1272.

Sagmeister M, Borovicka J, Knierim M, Magdeburg B, Meyenberger C.Perception of gastrointestinal endoscopy by patients and examiners withand without background music. Digestion 2003; 68:5-8.

Gubler C, Borovicka J, Diener P A, Meyenberger C. [Cholestatic hepatitis.27-year-old tool engineer]. Praxis 2003; 92:1269-72.

10

publications

title

journalpaper/review

Helbling B, Stamenic I, Viani F, Gonvers J J, Dufour J F, Reichen J,Cathomas G, Steuerwald M, Borovicka J, Sagmeister M, Renner E L,Investigators of the Swiss Association for the Study of the Liver .Interferon and amantadine in naive chronic hepatitis C: a double-blind,randomized, placebo-controlled trial. Hepatology (Baltimore, Md.) 2002;35:447-54.

Pescatore P, Jornod P, Borovicka J, Pantoflickova D, Suter W, MeyenbergerC, Blum A L, Dorta G. Epinephrine versus epinephrine plus fibrin glueinjection in peptic ulcer bleeding: a prospective randomized trial.Gastrointestinal endoscopy 2002; 55:348-53.

Albert S, Borovicka J, Thurnheer M, Meyenberger C. [Pre- andpostoperative transaminase changes within the scope of gastric bandingin morbid obesity]. Praxis 2001; 90:1459-64.

Albert S, Borovicka J, Thurnheer M, Meyenberger C. Prä- undpostoperative Transaminasenveränderungen im Rahmen derMagenbandeinlage bei morbider Adipositas. Schweiz. Runsch. Med. Prax.2001; 90:1459-1464.

Suter W R, Neuweiler J, Borovicka J, Fantin A C, Meyenberger C.Cytomegalovirus-induced transient protein-losing hypertrophicgastropathy in an immunocompetent adult. Digestion 2000; 62:276-9.

Borovicka J, Schwizer W, Guttmann G, Hartmann D, Kosinski M, WastielC, Bischof-Delaloye A, Fried M. Role of lipase in the regulation ofpostprandial gastric acid secretion and emptying of fat in humans: astudy with orlistat, a highly specific lipase inhibitor. Gut 2000;46:774-81.

11

publications

title

journalpaper/review

Borovicka J, Lehmann R, Kunz P, Fraser R, Kreiss C, Crelier G, Boesiger P,Spinas G A, Fried M, Schwizer W. Evaluation of gastric emptying andmotility in diabetic gastroparesis with magnetic resonance imaging:effects of cisapride. The American journal of gastroenterology 1999;94:2866-73.

Kunz P, Crelier G R, Schwizer W, Borovicka J, Kreiss C, Fried M, BoesigerP. Gastric emptying and motility: assessment with MR imaging--preliminary observations. Radiology 1998; 207:33-40.

Kreiss C, Schwizer W, Borovicka J, Jansen J B, Bouloux C, Pignol R,Bischof Delaloye A, Fried M. Effect of lintitript, a new CCK-A receptorantagonist, on gastric emptying of a solid-liquid meal in humans.Regulatory peptides 1998; 74:143-9.

Borovicka J, Schwizer W, Mettraux C, Kreiss C, Remy B, Asal K, Jansen JB, Douchet I, Verger R, Fried M. Regulation of gastric and pancreaticlipase secretion by CCK and cholinergic mechanisms in humans. TheAmerican journal of physiology 1997; 273:G374-80.

Schwizer W, Borovicka J, Kunz P, Fraser R, Kreiss C, D'Amato M, CrelierG, Boesiger P, Fried M. Role of cholecystokinin in the regulation of liquidgastric emptying and gastric motility in humans: studies with the CCKantagonist loxiglumide. Gut 1997; 41:500-4.

Schwizer W, Asal K, Kreiss C, Mettraux C, Borovicka J, Rémy B, GüzelhanC, Hartmann D, Fried M. Role of lipase in the regulation of uppergastrointestinal function in humans. The American journal of physiology1997; 273:G612-20.

Wells A S, Read N W, Fried M, Borovicka J, D'Amato M. Effects of aspecific CCK-A antagonist, Loxiglumide, on postprandial mood andsleepiness. Journal of psychopharmacology (Oxford, England) 1997;11:241-6.

12

publications

title

journalpaper/review

Schwizer W, Fraser R, Borovicka J, Asal K, Crelier G, Kunz P, Boesiger P,Fried M. Measurement of proximal and distal gastric motility withmagnetic resonance imaging. The American journal of physiology 1996;271:G217-22.

Lehmann R, Borovicka J, Kunz P, Crelier G, Boesiger P, Fried M, SchwizerW, Spinas G A. Evaluation of delayed gastric emptying in diabetic patientswith autonomic neuropathy by a new magnetic resonance imagingtechnique and radio-opaque markers. Diabetes care 1996; 19:1075-82.

Borovicka J, Gonvers J J. Use of a biopsy forceps with and withoutneedle. Gastrointestinal endoscopy 1996; 44:510.

Kreiss C, Schwizer W, Erlacher U, Borovicka J, Löchner-Kuery C, Müller R,Jansen J B, Fried M. Role of antrum in regulation of pancreaticobiliarysecretion in humans. The American journal of physiology 1996; 270:G844-51.

Borovicka J, Kreiss C, Asal K, Remy B, Mettraux C, Wells A, Read N W,Jansen J B, D'Amato M, Delaloye A B, Fried M, Schwizer W. Role ofcholecystokinin as a regulator of solid and liquid gastric emptying inhumans. The American journal of physiology 1996; 271:G448-53.

Borovicka J, Michetti P. Oesophageal hypersensitivity. Gut 1996;39:147-8.

Borovicka J, Schwizer W, Remy B, Fried M. Cerulein-induced changes inplasma amino acid concentrations are not a valid test for pancreaticinsufficiency. The American journal of gastroenterology 1995; 90:1111-5.

Fraser R, Schwizer W, Borovicka J, Asal K, Fried M. Gastric motilitymeasurement by MRI. Digestive diseases and sciences 1994;39:20S-23S.

13

publications

title

journalpaper/review

Schwizer W, Fraser R, Borovicka J, Crelier G, Boesiger P, Fried M.Measurement of gastric emptying and gastric motility by magneticresonance imaging (MRI). Digestive diseases and sciences 1994;39:101S-103S.

Stanghellini V, Borovicka J, Read N W. Feedback regulation and sensation.Frontiers in gastric emptying. Digestive diseases and sciences 1994;39:124S-127S.

Schwizer W, Borovicka J, Fried M, Inauen W. [Motility disorders andassessment methods of the esophagus]. Schweizerische medizinischeWochenschrift. Supplementum 1993; 54:8-14.

14

projects

title status

GA29145 ongoing- followup

Evaluation of High Resolution Chromoendoscopy with Lugol’sIodine and Acetic Acid for Detection of Early Dysplastic orNeoplastic Lesions of the Anal Canal in High−Risk Patients

scheduled

ALERT automat-icallyclosed

GA289103/Gardenia ongoing- followup

GA29144/Bergamot ongoing- followup

GA28950/Hickory ongoing- followup

Abbvie M14-033 ongoing- followup

Abbvie M 14-347 ongoing- followup

GA28951 ongoing- followup

15

projects

title status

Treatment of non-alcoholic steatohepatitis (NASH) patients withvitamin D

automat-icallyclosed

INSPIRADA scheduled

Diagnostic value of calprotectin measurement in ascitic fluid forthe diagnosis of Spontaneous Bac-terial Peritonitis

completed

Eine randomisierte, doppelblinde klinische Prüfung der PhaseIII zur Untersuchung der Wirksamkeit, Si-cherheit undVerträglichkeit von TMC435 vs. Telaprevir, beide in Kombinationmit PegIFNα-2a und Ribavirin, bei Patienten mit chronischerHepatitis-C-Genotyp-1-Infektion, die bei einer früherenTherapie mit PegIFNα- und Ribavirin Null- oder partielleResponder waren

completed

16

projects

title status

An International, Multi-Center Study Evaluating the Correlationof IL28B Genotypes with Chronic Hepatitis C DiseaseCharacteristics and Patient Demographics

completed

Non-Interventional Cohort Study on the Utilization and Impactof Dual and Triple Therapies Based on Pegylated Interferon forthe Treatment of Chronic Hepatitis C

completed

17

projects

title status

Eine explorative, randomisierte, placebokontrollierte,doppelblinde Studie mit parallelen Gruppen zur Untersuchungder pharmakodynamischen Wirkung von M0003 auf Reflux-Parameter bei Teilnehmern mit gastroösophagealem Reflux undpersistierenden Symptomen trotz Einnahme einer stabilenDosis eines Protonenpumpenhemmers

automat-icallyclosed

18

projects

title status

Multicenter, Open-Label, Early Access Program of Telaprevir inCombination With Peginterferon Alfa and Ribavirin in Genotype1 Chronic Hepatitis C Subjects With Severe Fibrosis andCompensated Cirrhosis

completed

pTNS: Perkutane tibiale Nervenstimulation zur Behandlung derDranginkontinenz für Stuhl

ongoing- followup

Prüfung der Verträglichkeit und Wirksamkeit von Everolimus inKombination mit Chemoembolisation (TACE) bei Lebertumoren(HCC)

completed

Laryngitis and Halitosis in Patients with GERD: Diagnostic andendoscopic Criteria

scheduled

IBD-Kohorte ongoing- followup