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Pediatric Allergies in America: A Landmark Survey of Nasal Allergy Sufferers EXECUTIVE SUMMARY Prepared for Nycomed Conducted by Schulman, Ronca and Bucuvalas, Inc. May 8, 2007 Supported by:
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Pediatric Allergies in America: A Landmark Survey of Nasal Allergy Sufferers

EXECUTIVE SUMMARY

Prepared forNycomed

Conducted bySchulman, Ronca and Bucuvalas, Inc.

May 8, 2007

Supported by:

1

Study Design

Physician Survey: 3/8/07 – 4/17/07

100

100101

100

5050

20 minutesAMA/AOA Master List

State Licensing BoardAmerican Academy of Physician Assistants

Health Professional Survey

-- Pediatrics-- Family Practice

-- Allergy

-- Otolaryngology-- Nurse practitioner

-- Physician assistant

Cross-section: 3/7/07 – 4/25/07

500

504

18 minutes

36 minutes

National RDDPopulation Aged 4-17� with allergies

� without allergies

Completed Sample

Interview Length

Sampling FramePopulation

2

Seasonal or Perennial Allergies

Not sure, 1%

Seasonal, 63%

Throughout the year, 37%

Q12. Would you describe your (AGE)’s nasal allergies as seasonal or do they occur throughout the year? N=500

3

Season Allergies Are the Worse

76%

16%

34%

13%

2%

0%

20%

40%

60%

80%

100%

Spring Summer Fall Winter Not Sure

Q13b. During what times of the year are your (AGE)’s nasal allergies the worse? Base: Worse at certain times N=434

4

Symptoms During Worst Month

25%

15%

12%

25%

5%

12%

3%

2%

2%

18%

15%

9%

21%

19%

17%

27%

10%

15%

7%

5%

16%

15%

10%

2%

0% 20% 40% 60% 80% 100%

Repeated Sneezing

Watering Eyes

Red, itching eyes

Stuffed up nose

Awakened / Unable to Sleep

Itching

Headache

Ear Pain

Facial Pain

Runny Nose

Post-nasal drip

Dry Cough

Every day

Most days

Q14. During the worst one month period in the past year, did your (AGE) have (symptom) every day, most days a week, a few days a week, a few days a month, less than that, or never? N=500

5

How Bothersome are Symptoms

17%

18%

16%

35%

41%

39%

47%

37%

13%

23%

25%

18%

22%

32%

22%

16%

43%

40%

36%

37%

34%

34%

0% 20% 40% 60% 80% 100%

Repeated Sneezing

Watering Eyes

Red, itching eyes

Stuffed up nose

Itching

Headache

Ear Pain

Facial Pain

Runny Nose

Post-nasal drip

Dry Cough

Extremely

Moderately

Q15. When your (AGE) had nasal allergy attacks, how bothersome are the following symptoms usually --- extremely bothersome, moderately bothersome, slightly bothersome, or not bothersome ? N=500

6

Most Bothersome Symptom of Nasal Allergies

27%

13%

7%

8%

12%

7%

2%

5%

3%

4%

9%

2%

0% 5% 10% 15% 20% 25% 30%

Stuffed up nose

Headache

Post-nasal drip

Red, itching eyes

Runny Nose

Repeated Sneezing

Facial Pain

Watering Eyes

Ear Pain

Itching

Dry Cough

Not Sure

Most bothersome

Q16. Which of these symptoms was the most bothersome to your (AGE)? Base: Had bothersome symptoms N=438

7

Degree of Discomfort from Nasal Allergies

Not sure1%

Can't Tolerate33%

Can Ignore8%

Can Tolerate57%

Q17. In general, when your (AGE) has a nasal allergy attack would you say that (his/her) discomfort is usually something (he/she) can ignore, (he/she) can’t ignore it, but (he/she) can tolerate it, or (he/she) can’t tolerate it without relief? N=500

8

At Least Somewhat Troubled by Symptoms

26%

29%

12%

8%

12%

32%

0% 10% 20% 30% 40% 50%

Difficulty in getting to sleep

Waking up during the night

Lack of a good night'ssleep

Allergy N=500 Not Allergy N=504

QR3a-c. How troubled has your (AGE) been by each of these symptoms during the last week as a result of his/her nasal symptoms --- not troubled, hardly troubled, somewhat troubled, moderately troubled, quite a bit troubled, very troubled or extremely troubled?

9

General Health Rating

43%

33%

18%

5%

1%

59%

26%

11%

4%1%

0%

10%

20%

30%

40%

50%

60%

70%

Excellent Very good Good Only fair Poor/Very Poor

Per

cent

of r

espo

nden

ts

Allergy N=500 Not allergy N=504

Q1. In general, would you say that your (AGE)’s health is excellent, very good, good, only fair, poor or very poor?

10

Activity Limitation in Past 4 Weeks

21%23%

22%23%

11% 10% 10% 10%

0%

10%

20%

30%

40%

50%

Been limited inkind of work

Difficulty inperforming

Cut down onamount

Accomplished less

Per

cent

of r

espo

nden

ts

Allergy N=500 Not allergy N=504

N2a. During the past four weeks has your (AGE)… been limited in the kind of work or other activities he/she could do as a result of his health? N2b. … had difficulty in performing work or other activities …?N2c. … had to cut down on the amount of time spent on his/her regular daily activities…? N2d… accomplished less than he/she would like to….?

11

Positive Feelings: All of the Time

32%

18%

37%

28%

51%

29%

50%

32%

0%

10%

20%

30%

40%

50%

60%

70%

Full of Life Calm and Peaceful Lots of Energy Been Hap py

Per

cent

of r

espo

nden

ts

Allergy N=500 Not allergy N=504

N3a-g.During the past 4 weeks how often has your (AGE) ……… --- all of the time, most of the time, a good bit of the time, some of the time, little of the time, or none of the time?

12

Negative Feelings: Little or None of the Time

49%

61%

80%

73%

63%

77%

90%

84%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Felt Tired Felt Worn Out Downhearted or Blue Been Nerv ous

Per

cent

of r

espo

nden

ts

Allergy N=500 Not allergy N=504

N3a-g.During the past 4 weeks how often has your (AGE) ……… --- all of the time, most of the time, a good bit of the time, some of the time, little of the time, or none of the time?

13

Extremely or Very Important to Child

64%

81%

42%

85%

82%

62%

72%

65%

66%

82%

43%

88%

78%

52%

73%

66%

0% 20% 40% 60% 80% 100%

Playing organized sportsor exercising*

Doing well in school*

School activities*

Doing things with family

Going out/playing withfriends

Having pets

Outdoor activities

Indoor activities

Allergy N=500 Not Allergy N=504

N7. In your opinion, how important are each of the following to your (AGE)? Would you say it is extremely important, very important, somewhat important or not too important?

* Excludes 4 and 5 year olds

14

Allergies/Health Interferes a Lot or Some

32%

26%

17%

23%

29%

27%

31%

12%

10%

9%

5%

5%

7%

4%

7%

5%

8%40%

0% 10% 20% 30% 40% 50%

Organized sports or exercising*

Doing well in school*

School activities*

Doing things with family

Going out/playing with friends

Having pets

Outdoor activities

Indoor activities

Sleeping

Allergy N=493 Not Allergy N=432

N9. How much do you feel your (AGE)’s allergies/health limit what he/she can do in the following areas --- a lot, some, only a little or not at all?

* Excludes 4 and 5 year olds

15

Allergies/Health Interfered with School or Daycare in the Past 12 Months

Q23a. Aside from actually missing (school/daycare), has his/her allergies/health interfered with his/her performance at school? Base: In school or daycare

40%

58%

2%

11%

89%

0%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Yes No Not sure

Per

cent

of r

espo

nden

ts

Allergy N=472 Not Allergy N=453

16

Productivity and Allergies97%

68%

0%

20%

40%

60%

80%

100%

No Symptoms N=486 Symptoms at worst =487Q24. Thinking about your (AGE)’s ability to do things (he/she) wants to on a scale of 0 to 100, where 100 means

100% able, where would you rank (his/her) ability on days when (he/she) don’t have nasal allergy symptoms? Q25. Where would you rank your (AGE)’s ability on the same scale of 0 to 100 … when (his/her) nasal allergies are

at their worst?

Mean Productivity

17

Current Medication Use for Nasal Allergies

Q63a. In the past 4 weeks, has your (AGE) used any over-the-counter, non-prescription medicine to give (him/her) relief from nasal allergy symptoms? Q64a. In the past 4 weeks, has your (AGE) used any prescription nasal spray for (his/her) nasal allergies? Q72a. Has your (AGE) taken any other prescription medications for (his/her) nasal allergies in the past 4 weeks? N=500

54%

26%

34%

48%

76%

24%

0%

20%

40%

60%

80%

100%

OTC Rx NasalSpray

Other Rx Any Rx AnyMedication

NoMedication

18

Symptom Relief from Current Intranasal Corticostero id

Q65. Does your (AGE)’s current prescription nasal spray give (him/her) relief from all of (his/her) symptoms, most symptoms, some symptoms, or no symptoms? Base: Uses intranasal corticosteroid N=129

Not sure, 3%

None, 4%Some, 29%

Most, 47%

All, 17%

19

Onset of Relief from Current Intranasal Corticosteroid

Q68. How long does it take for your (AGE)’ current prescription nasal spray to begin giving (him/her) symptom relief? Uses intranasal corticosteroid N=130

19%

31%

11%

2%0% 1% 1%

19%

4%

14%

0%

10%

20%

30%

40%

50%

Within 1hour

1 hour 2 hours 3-4hours

5-6hours

7-10hours

11-23hours

1-6days

Oneweek or

more

NotSure

20

Does Current Intranasal Corticosteroid Provide 24 Hour Relief

Q69a. Does your (AGE)’s current prescription nasal spray lose effectiveness over the course of the day or night, or does it remain as effective as when (he/she) first took it? Base: Uses intranasal corticosteroid N=130

Not sure, 14%

Does not, 36%

Loses effectiveness, 51%

21

Change Prescription Medicines for Nasal Allergies

Q81a. How often does your (AGE) change nasal allergy medicines ---several times each year, once a year, every few years, only rarely or never? N=500

Several times a year, 8%

Not sure, 3%

Once a year, 8%

Every few years, 10%Only rarely, 31%

Never, 40%

22

Why Changed Medicine for Nasal Allergies

Q81b. Why has your (AGE) changed nasal allergy medicines? Anything else? Base: Has changed nasal allergy medicines. N=284

39%

22%

6%

5%

3%

6%

4%

1%

4%

3%

1%

4%

12%

0% 10% 20% 30% 40% 50%

Not effective enough

Doctor wanted to try other

Patient wanted to try other

Bothersome side effects

Cost/co-pay

Didn't treat symptoms

Not covered

Safety concerns

Not long lasting enough

Hard to take

Not fast enough

Not sure

Other

23

Why Dissatisfied with Nasal Allergy Medicine

Q82c. Why were you (or he/she) dissatisfied with that medicine? Base: Have asked doctor to change nasal allergy medicines. N=128

61%

16%

9%

9%

1%

2%

1%

8%

1%

0% 20% 40% 60% 80% 100%

Wasn't effective

Bothersome side effects

Effectiveness wore off

Didn't provide 24 hour relief

Cost/co-pay

Hard to administer

Dosing Schedule

Other

Not sure

24

Effectiveness Wears Off Over Time

Q88a. Have you ever found that a prescription spray’s effectiveness in treating your (AGE)’s nasal allergy symptoms wears off over time even when (he/she) is taking the medicine as prescribed?

Q88b. Has this happened to your (AGE) with more than one prescription nasal allergy spray? N=500

Not sure, 25%

No, 46%

Yes, not sure how many, 1%

Yes, one, 15%

Yes, more than one, 13%

25

Commonly Reported Side Effects of Prescription Nasal Sprays

19%

6%

21%

5%3% 3%

10%

3%

8%

5%

9%

7%

13%

10%

9%

1%2%

5%

0%

10%

20%

30%

40%

50%

Bad taste Burning Dripping downthroat

Drying feeling Headaches Drowsiness

Some

Most

All

Q90. How many of the prescription sprays that your (AGE) has taken for nasal allergies had the following types of side effects --- all, most, some, few or none? N=500

26

Severity of Commonly Reported Side Effects of Prescription Nasal Sprays

12%7%

10%

5% 5% 4%

16%

8%

19%

9% 8%7%

0%

10%

20%

30%

40%

50%

Bad taste Burning Dripping downthroat

Drying feeling Headaches Drowsiness

Moderately

Extremely

Q91. How bothersome are the following side effects of prescription sprays for nasal allergy --- extremely, moderately, slightly or not bothersome? N=500

27

Reason Stopped Taking Nasal Allergy Prescription

Q94. Has your (AGE) ever stopped taking a nasal allergy spray prescribed by (his/her) doctor because…. N=500

14%

14%

13%

13%

5%

4%

2%

6%

5%

53%

0% 10% 20% 30% 40% 50% 60%

Didn't find it effective

Effectiveness began wearing off

Didn't provide 24 hour relief

Bothersome side effects

Not covered

Co-pay was too high

Dosing schedule was difficult

Hard to administer

Concern about safety

None of these

28

Failed to Follow Physician Instructions

Q108. People with nasal allergies sometimes fail to follow their physician’s instructions about their medicines for their nasal allergies. Has your (AGE) ever failed to take an allergy medicine as prescribed because of ……N=500

26%

24%

39%

20%

19%

12%

17%

17%

14%

0% 10% 20% 30% 40% 50%

Lack of symptom relief

Loss of effectiveness over time

Lack of symptoms

Troublesome side effects

Worry about side effects

Cost of drugs

Concern about long term use

Poor toleration

Concern about safety

29

Discomfort During Allergy Attack: Patients and Practitioners

P8. In general, would you say that patients’ 4 to 17’s discomfort during a nasal allergy attack is usually something they can ignore, they can’t ignore it, but they can tolerate it, or they can’t tolerate it without relief? N=501

Q17. In general, when your child has a nasal allergy attack would you say that (his/her) discomfort is usually something s/he can ignore, s/he can’t ignore it, but s/he can tolerate it, or s/he can’t tolerate it without relief? N=500

26%

55%

38%

27%

28%

33%

64%

57%

70%

56%

41%

71%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Pediatrician

Family Practice

Nurse Prac./PhysicianAsst.

Patients

Can't tolerate Can't ignore

30

Productivity when Nasal Allergies are at Their Worst: Patients and Practitioners

P10. Thinking about productivity at school on a scale from 0 to 100, where 100 means 100% productivity, where would you rank the productivity of patients 4 to 17 with allergic rhinitis, when their nasal allergies are at their worst? N=501

Q25. Where would you rank your child’s ability to do the things (he/she) wants to on the same scale of 0 to 100, where 100 means 100% able, when (his/her) nasal allergies are at their worst? Base: 487

Mean

59%

68%

61%66%

54%55%

0%

20%

40%

60%

80%

100%

ENT Allergist Pediatrician FamilyPractice

NP/PA Patients

31

Percent Very Satisfied With Disease Management: Patients and Practitioners

P20. Approximately, what proportion of your patients aged 4 to 17 with nasal allergies would you say are VERY satisfied with the management of their disease? Would you say… N=501

Q51. Overall, how satisfied are you with (his/her) health practitioner’s management and treatment of your (AGE)’snasal allergies? N=500

73%77%

68%

1%

68%

2%4%4%3%

58%

75%

0%

20%

40%

60%

80%

100%

ENT Allergist Pediatrician Family Practice NP/PA Patients

All (91% to 100%) Most (51% to 90%)

32

Satisfaction with Intra-nasal Corticosteroids: Patients and Practitioners

P36. In general, how satisfied are your patients aged 4 to 17 with allergic rhinitis with their intra-nasal corticosteroids? Would you say that they are very satisfied, somewhat satisfied, somewhat dissatisfied, or very dissatisfied? N=501

Q70b. In general, how satisfied have you been with the prescription nasal spray your (AGE) has used for (his/her) nasal allergies in the past? Base: Ever used Rx nasal spray for nasal allergies. N=335

18%

72%

69%

61%

70%

43%33%

31%

37%

26%

22%

57%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Pediatrician

Family Practice

NP/PA

Patients

Very satisfied Somewhat satisfied

33

Money’s Worth from Prescription Allergy Medicines: Patients and Practitioners

P30. Overall, do your patients aged 4 to 17 feel they get their money’s worth out of prescription medicines for nasal allergies? N=501

Q97. Overall, do you feel that patients get their money’s worth out of prescription medicines for nasal allergies? N=500

80%

63%

84%88%

82%

74%

0%

20%

40%

60%

80%

100%

ENT Allergist Pediatrician FamilyPractice

NP/PA Patients

34

Attitudes about Nasal Allergies: Agree

88%

69%

35%

59%

75%

81%

28%

75%

67%

25%

62%

75%

76%

44%

0% 20% 40% 60% 80% 100%

Nasal allergies are serioushealth problem in US

Nasal allergies usually causesome lifestyle limitations

There are no truly effectivetreatments for nasal allergies

Frequent nasal allergysymptoms can be prevented

Nasal allergies can makeasthma worse

Nasal allegies can cause sinusinfections

Rx nasal sprays are not safe forchildren

Allergy N=500 Not allergy N=504

Q110. Now I am going to read you a series of statements. As I read each statement , please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement.

35

Need for Patient Education: Patients and Practitioners

P45. How much need do you think there is for better education of PARENTS OF CHILDREN WITH NASAL ALLERGIES about their condition and its treatment? Do you think there is a… N=501

Q113. How much need do you think there is for better education of PARENTS OF CHILDREN with nasal allergiesabout their condition and its treatment? N=500

54%

56%

51%

60%

50%

45%

42%

40%

45%

38%

41%

55%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Pediatrician

Family Practice

NP/PA

Patients

Strong need Moderate need


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