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Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan...

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Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018
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Page 1: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Pelvic Pain

Miss Tracy-Louise Appleyard

Consultant O&G

NBT 30 Jan 2018

Page 2: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• No commercial conflicts of interest

• Working Group for CPP PHE • Endometriosis Centre, NBT

• GP

• Lt Col RAMC, Commissioned 1992

Page 3: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 4: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Pain

• An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage

– International Association for the Study of Pain

Page 5: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Pelvic Pain - definition

• “abdominal pain occurring below the level of the umbilicus”

International Association for the Study of Pain

• Acute vs Chronic

• Men vs Women

Page 6: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• Improve understanding of pelvic pain

• Options available in GP

Page 7: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Chronic Pelvic Pain in Women

Miss Tracy-Louise Appleyard

Consultant O&G

NBT 26 Sept 2014

Page 8: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 9: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Definition…

• ‘exasperate, defeat and overwhelm their doctors by their behaviour’ – Patient

• ‘clinicians feeling helpless in the face of those patients who seek salvation for psychological, social and spiritual problems at a biomedical level’ – Doctor

Page 10: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

If there was a condition that made 10% of mens testicles hurt, with pain during intercourse, there would be a river flowing out of my GP surgery doors from the volume of male tears being shed in the waiting room

• Martin Hirsch

Page 11: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

RCOG definition

• Intermittent or constant pain • Lower abdomen or pelvis of a woman • ≥ 6 mths • Not occurring exclusively with

menstruation or intercourse and not associated with pregnancy

• Symptom not a diagnosis

Page 12: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• Unfunded report from Pain Australia and the Faculty of Pain Medicine at the Australian and New Zealand College of Anaesthesia 2011

Page 13: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Prof Michael Cousins..

• ‘…pelvic pain has suffered from particularly inappropriate stigmatism and neglect, with resulting disastrous effects on women and young girls…’

Chairman of the IASP International Pain Summit Montreal 2010

Page 14: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Remarks…

• Reluctance of women to seek medical care – Patients often given uniformed explanations of pain

– Often feel dismissed

• Gynaecology may be slow to pick up on some of the advances in pain research – New nerve growth in endo lesions

– Chemical stimulation of inflammatory processes

– Inadvertent nerve damage as a result of surgery

Page 15: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Prevalence

• CPP - 38/1000 women in primary care – asthma 37/1000

– chronic back pain 41/1000

• May significantly impact on a woman’s ability to function

Grace V, Zondervan K. Health Care Women Int 2006;27:585–99. Zondervan et al Br J Obstet Gynaecol 1999;106:1149–55.

Page 16: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Prevalence

Page 17: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Prevalence

• Dysmenorrhoea (106 studies)

17-81% prevalence

• Dyspareunia (54 studies)

8-22% prevalence

• Non cyclical pain (18 studies)

2% to 24% prevalence

Page 18: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Potential ‘causes’?

Page 19: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Potential ‘causes’

Recognised pathologies

• Endometriosis/adenomyosis*

• Adhesions

• Ovarian remnant*

• Residual ovary*

• * Cyclical pattern

No obvious pathology

• Pelvic congestion*

• Primary dysmenorrhoea*

• Midcycle pain*

• IBS

• Entrapped nerve syndrome – Neuropathic pain

• Painful bladder syndrome

Page 20: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 21: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 22: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 23: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Guidelines?

Page 24: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

RCOG 2012

Page 25: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

History

• Story ….

Page 26: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 27: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 28: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Advanced listening…

Page 29: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Suspect endometriosis…

Page 30: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Endometriosis S & S

• CPP

• Dysmenorrhoea – Premenstrual pain

• Deep dyspareunia

• Dyschezia – Cyclical bowel symptoms

• Dysuria

• Subfertility with 1 or more of above

Page 31: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

NICE Sept 2017

Page 32: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

NICE May 2014

Page 33: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

ESHRE 2013

Page 34: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Management

Page 35: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

‘ICE’… Becker & Maiman (1975)

Woman

Ideas

Concerns Expectations

Page 36: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 37: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 38: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 39: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Recently…

Page 40: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis
Page 41: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• Summarise

• Empathasise

– Empathasise • Empathasise

• What is your expectation of today?

• Recognise, share and ask permission to explain

Page 42: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

‘ICE’… Becker & Maiman (1975)

Woman

Ideas

Concerns Expectations

Partnership

Management plan

Page 43: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Investigations?

Page 44: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• Pain diary

• Offer abdo/pelvic exam

Page 45: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Diagnostic tests

• USS • Ca125

• MRI

• Diag lap

Page 46: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

TVS

• Ovarian endometrioma

• ?rectal endometriosis

• 3D not proven for RV disease

Page 47: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Ca125

• NOT to be used to diagnose endometriosis

• Persistent or frequent (>12 x/mth): – Bloating

– Early satiety

– PP

– Urinary urgency or frequency

– >50yrs, any new IBS symptoms*

Page 48: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Refer?

• GOPC – Severe, PPP or recurrent symptoms of

endometriosis

– Pelvic signs of endometriosis

– Initial Mx not effective, not tolerated or contraindicated

• Specialist endo centre – Suspected or confirmed deep endo

involving bladder, bowel, ureter

• <17yrs??

Page 49: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Diagnostic laparoscopy

• Gold standard?? – 50% of laparoscopies – negative – Accuracy of visual diagnosis – No longer using the scoring systems

• ?2nd line

• Can develop woman’s belief about her pain

Page 50: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

The new ‘oscopy

• Micro-laparoscopy

• Conscious pain mapping

• Patient assisted laparoscopy (PAL)

• NOTES

– Not widely adopted

– ?acceptability, validity, reproducibility

Page 51: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Endometriosis pain

Page 52: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Medical Mx

• Analgesia

– 3mths paracetamol+/- NSAIDs

• Neuropathic pain

– Amitriptyline, Duloxetine, Pregabalin, Gabapentin

– SSRI

• Hormonal treatment

• COCP, Prog, Mirena

Page 53: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

NICE Nov 2013

Page 54: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Other Mx

• Dietary Mx

– Dyspepsia

• Physio

• Mindfulness

• CBT

Page 55: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Surgical Mx

• ? Priorities for pain and fertility

• Laparoscopy

• Diag vs treatment

• ?GnRHa

• Excision > ablation

• Post-op medical Mx

• Hysterectomy + excision (TLH)

Page 56: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

HRT post oophorectomy

• Continuous combined tibolone or

• Combined oest/prog

• Begin immediately post-op

• Consider combined if:

– residual endometriosis after radical surgery

– severe disease

– obese patients

• ?prog chance of hyperplasia or malig transformation in residual disease

Page 57: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

• PR bleeding • New bowel symps >50 yrs • New pain postmenopause • Pelvic mass • Suicidal ideation • ++ weight loss • IMB/Irreg > 40yrs • PCB

Page 58: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

GP role

• Avoid multiple diagnostic tests • Focus on rtn to normal daily

activities/QoL • Evidence based

– balance harms and benefits of all approaches

• Filter • Ongoing management • Refer

Page 59: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Role of the specialist?

• Endometriosis centre • Avoid multiple diagnostic tests • Avoid fertility destroying surgeries • Filter • Specific role within the CPP team • Focus on return to normal daily

activities/QOL • Evidence based

– balance harms and benefits of all approaches

• Assist the GP

Page 60: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

Info & Support

• Endometriosis UK

• IBS network

• Cystitis and Overactive Bladder Foundation

• Women’s Health

• Pelvic Pain Support Network

• Department of Health Expert Patient Initiative

• RCOG

Page 61: Pelvic pain · 2018-01-31 · Pelvic Pain Miss Tracy-Louise Appleyard Consultant O&G NBT 30 Jan 2018 •No commercial conflicts of interest •Working Group for CPP PHE •Endometriosis

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