Pendik Pendik VeterinaryVeterinaryControl and Control and ResearchResearchInstituteInstitute

Istanbul/TurkiyeIstanbul/Turkiye

HistoryThe first bacteriology laboratory was The first bacteriology laboratory was founded founded in the country in in the country in the name of the name of ``Bakteriyolojihane-i Osmani`` ``Bakteriyolojihane-i Osmani`` (Bacteriologyhouse of Ottoman) (Bacteriologyhouse of Ottoman) in 1894in 1894 under the management of Dr. Mourice under the management of Dr. Mourice Nicolle from France. Nicolle from France.

In the same year In the same year cattle plague serum cattle plague serum productionproduction had been had been started.started.

In 1912In 1912 institute was transferred to its institute was transferred to its final location in final location in Pendik.Pendik.

During that period During that period BarbonBarbon ((Pasteurellosis bubalorumPasteurellosis bubalorum)) vaccine, vaccine, Tuberculin and MalleinTuberculin and Mallein had been had been started to productionstarted to production..

FollowingFollowing the proclamation of Turkish the proclamation of Turkish Republic, the phase of improvements Republic, the phase of improvements startedstarted in 1923 in 1923..

During During 1949-1964 first contacts with 1949-1964 first contacts with FFAOAO,, pathology laboratory founded, pathology laboratory founded, revolving fund established.revolving fund established.

During 1965-2001 equipments updated During 1965-2001 equipments updated and institute magazine and institute magazine was was establishedestablished..

Responsibilities

Pendik Veterinary Control and Pendik Veterinary Control and Research Institute is directly committed Research Institute is directly committed and works under and works under Turkish Ministry of Turkish Ministry of Agriculture and Rural AffairsAgriculture and Rural Affairs (MARA) (MARA). .

Pendik Inst. serves to 1Pendik Inst. serves to 122 provincesprovinces in in Trakya and Marmara Regions in some Trakya and Marmara Regions in some parts of their duties and serves to all parts of their duties and serves to all country with the other duties such as country with the other duties such as biological productions, diagnostics and biological productions, diagnostics and drug quality controls.drug quality controls.

Provinces under the responsibility of the Veterinary Control and Research Institutes  

  CVCRI, Etlik-Ankara

VCRI, Pendik-Istanbul

VCRI, Bornova-Izmir**

VCRI, Konya*

VCRI, Elazig

VCRI, Samsun

VCRI, Adana

VCRI, Erzurum

•The institute continues in the fields of The institute continues in the fields of researches,researches, diagnostics services,diagnostics services, production,production, education,education, publishing,publishing, strategy and project development.strategy and project development.

•With these studies institute has established With these studies institute has established bounds with organisations such as bounds with organisations such as FAO, OIE, FAO, OIE, EUEU, , VLAVLA, , IAEA, AFFSA, IAEA, AFFSA, WHO-MZCCWHO-MZCC and and developed common projects and strategies. developed common projects and strategies.

DIRECTORDIRECTORDIRECTORDIRECTORRESEARCH COMMITTEE

RESEARCH AND PUBLICITY COORDINATION

SUPPORT MANINTANENCE

DEPUTY DIRECTORTECHNICAL

DEPUTY DIRECTORADMINISTRATION

SUPPORT MAINTENANCE

PHARMACOLOGYDEPARTMENT

PRODUCTIONDEPARTMENT

DIAGNOSTICSDEPARTMENT

•DRUG QUALITY CONTROL LAB.•RESIDUE LAB.•TOXICOLOGY LAB

•ANAEROB PRODUCTION LAB.•AEROB PRODUCTION LAB.•VIRAL VACCINESPRODUCTION LAB.•BRUCELLA PRODUCTION LAB.•MYCOPLASMA PRODUCTION LAB.•PARASITARY VACCINES PRODUCTION LAB.•PRODUCTION CONTROL UNIT

•BACTERIOLOGICAL DIAGNOSTICS LAB.•POULTRY DISEASES DIAGNOSTICS LAB.•PATHOLOGY LAB.•RABIES DIAGNOSTICS LAB.•VIRAL DIAGNOSTICS LAB.•SEROLOGICAL DIAGNOSTICS LAB.•PARASITARY DIAGNOSTICS LAB.•AQUA PRODUCTS AND FISH DISEASES DIAGNOSTICS LAB.•MOLECULAR MICROBIOLOGY LAB.•MYCOPLASMA REFERENCE DIAGNOSTICS LAB.•SHEEP-GOAT POX REFERENCE DIAGNOSTICS LAB.•THEILERIA ANNULATA REFERENCE DIAGNOSTICS LAB.•ANAEROB REFERENCE DIAGNOSTICS LAB.•EPIDEMIOLOGY STATISTICS UNIT•SAMPLE RECEIVING UNIT

PERSONNEL GENERAL BUDGET

REVOLVING FUND INVENTORY WAREHOUSE SUPPORT MAINTENANCE•VEHICLE

•SECURITY

•MANAGERIAL HEADQUARTER

•SHIPPING

Organisation Schema

• Pendik Inst. is now producing Pendik Inst. is now producing

• 17 vaccines 17 vaccines

• 22 serums, antigen and biological 22 serums, antigen and biological materials. materials.

• Right now Pendik Inst. continues to Right now Pendik Inst. continues to serve with serve with

• 2323 laboratories under laboratories under 33 departments. departments.

Organisation Schema

•Number of employees;•Dr. Vet. Med : 24•Vet. Med. : 28•Biologist, Chemist :

6•Enginer : 3•Technician : 15•Staff : 24•Worker : 49

National References

• Sheep and Goat Pox• Animal Brucellosis• Animal Mycoplasmosis • Anaerob Diseases• Theileria annulata• Marek’s Diseases• Residues (Chloramphenicol, nitrofuran etc)• Avian Influenza

AVIAN INFLUENZA IN TURKEY

Avian Influenza outbreaks in Turkiye

• First occurence of Avian Influenza in Turkiye was defined on

• 5 October 2005 in province of Balıkesir, Manyas district, Kızıksa town

• As a result of measures taken got under control. Progress was regularly reported to international organisations.

• Second outbreak was on 15 December 2005 from Iğdır province’s Aralık district, in East Anatolia Region.

• H5N1 type of Avian Influenza was identified by National Reference laboratory on 26 December 2005 and it was also confirmed by Weybridge-England which is EU reference laboratory as type H5N1 on 07 January 2006.

Avian Influenza25 December 2005 – 26 February 2007

• 247 confirmed caseso 246 of which were of HPAI H5N1 viruso 1 of which was of LPAI H7N1 virus.

• Amongst these outbreakso 217 outbreaks in domestic poultry

- 216 were determined in backyard flocks - 1 was small scale commercial flock in Elazıgo 30 cases were determined in wildlife

Avian Influenza

• The latest confirmed wild bird case in February 2006.

• The latest confirmed case in domestic poultry in February 2007.

• The most recent disease report that has led to a confirmed case was on 26 February 2007

• Notification OIE and EU

The disease was observed in 53 of the 81 provinces. 19 had one confirmed outbreak, 14 had 2 confirmed outbreaks.3 had more than 10 confirmed Samsun had around one quarter of the national total of confirmed outbreaks, 59.

Confirmed cases of HPAI by domestic and wild

bird

AZARBAAZARBAIJAN

Wild Birds,

• Domestic poultry

Avian influenza diagnosis During the Avian influenza diagnosis During the OutbreaksOutbreaksin Pendik Veterinary Control and Research Institutein Pendik Veterinary Control and Research Institute

• Poultry disease,

• Serology,

• Molecular Microbiology Laboratories

• work together in the field of diagnosis of avian influenza including H5N1.

PENDIK VETERINARY CONTROL AND RESEARCH INSTITUTEAVİAN INFLUENZA DIAGNOSIS (11.10.2005-07.04.2006)

TOTAL CASES TOTAL SAMPLES NEGATIVES POSITIVES

Domestic Wild Domestic Wild Domestic Wild Domestic Wild

812 594 1389 889 1320 880 69 9

1406 2278 2200 78

58 ISOLATES; 57 H5N1 1 H7N1

The European Union’s Technical Assistance Programme for Turkey

 

Technical Assistance To Avian Influenza Preparedness & Response Project in

Turkey

TR 06.AI/SV

This project is financed by the European Union

The Project is implemented by Conseil Santé SA

http://www.kkgm.gov.tr/TR_06_AI_SV_new/index.htm

PROJECT PURPOSE

Overall objectiveThe overall objective of the project is to minimize the threat

in Turkey posed to humans by Highly Pathogenic Avian Influenza (HPAI) infection in domestic poultry and other animals, to diminish the burden of disease and loss of productivity, and to improve influenza pandemic preparedness and the response to this and other infectious disease threats to humans.

Project purposeThe project purpose is to support MARA and MoH in policy

and strategy development for AI preparedness & control and strengthening the capabilities of Veterinary Services for effective and efficient AI disease control and eradication activities.

PROJECT PURPOSE

• Results to be achieved1. National strategy developed and regulatory framework improved;2. Epidemiology studies and surveillance programmes improved and disease information systems upgraded;3. Veterinary services strengthened and inter-institutional coordination improved;4. Public awareness raised regarding good poultry keeping practices and bio-security measures.

BACKGROUND OF THE PROJECT

• Eight regional Veterinary Control and Research Institutes (VCRIs) provide laboratory services with the ability to achieve virus isolation. Three of them, Bornova, Pendik and Etlik institute AI laboratories in charge of virus identification. Bornova institute the national reference laboratory. They are equipped and competent to undertake a broad range of standard diagnostic HPAI tests and provide technical backstopping to the other 5 regional laboratories authorized for AI diagnostics. However the conditions of those three laboratories do not meet the required bio-safety standards. Therefore GDPC plans to upgrade them to BSL 3.

Contact PVCRI:Contact PVCRI:Batı Mahallesi Ankara Cad.

No:1 34890

Pendik/İSTANBUL

Tel.: +90 216 390 12 80

Fax: +90 216 354 76 92E-mail:pendik@penvet.gov.tr

Web:http://www.penvet.gov.tr

Thank youThank you