+ All Categories

Perform 3

Date post: 13-Jan-2015
Category:
Upload: paultatore
View: 666 times
Download: 1 times
Share this document with a friend
Description:
 
Popular Tags:
29
Issue III, 2004 Fun Ways to Work Exercise into Your Daily Routine 10 Fun Ways to Work Exercise into Your Daily Routine 10 Fun Festival GETAWAYS Around the Country Fun Festival GETAWAYS Around the Country How to Choose a Health Club That’s Right for You How to Choose a Health Club That’s Right for You SPICE UP YOUR SUMMER With Quick and Easy Barbecue Recipes Cycle Your Way Through American History SPICE UP YOUR SUMMER With Quick and Easy Barbecue Recipes Explore Scenic Lake Tahoe THINK POSITIVE: It Can Help You Live Longer! THINK POSITIVE It Can Help You Live Longer! Astronaut Sally Ride’s New Mission Astronaut Sally Ride’s New Mission James Caan He’s made over seventy films without missing a day of work, and now he has a hit TV series. He’s back on top, and still going strong. James Caan He’s made over seventy films without missing a day of work, and now he has a hit TV series. He’s back on top, and still going strong.
Transcript
Page 1: Perform 3

Issue III, 2004

Fun Ways to WorkExercise into YourDaily Routine10Fun Ways to WorkExercise into YourDaily Routine10

Fun FestivalGETAWAYSAround the Country

Fun FestivalGETAWAYSAround the Country

How to Choose a Health ClubThat’s Right for YouHow to Choose a Health ClubThat’s Right for You

SPICE UPYOUR SUMMERWith Quick and Easy Barbecue Recipes

Cycle Your Way ThroughAmerican History

SPICE UPYOUR SUMMERWith Quick and Easy Barbecue Recipes

ExploreScenic Lake Tahoe

THINK POSITIVE:It Can Help You Live Longer!THINK POSITIVEIt Can Help You Live Longer!

Astronaut Sally Ride’sNew MissionAstronaut Sally Ride’sNew Mission

James CaanHe’s made over seventy films without missinga day of work, and now he has a hit TV series.

He’s back on top, and still going strong.

James CaanHe’s made over seventy films without missinga day of work, and now he has a hit TV series.

He’s back on top, and still going strong.

64342_A.r2 2/10/05 2:18 PM Page 1

Page 2: Perform 3

““The rThe race is not alwace is not always to the swiftays to the swift...but to those who k...but to those who keep on runningeep on running..””

“Act as if it were impossible to fail.”

“We come to feel as we behave.”

“I bend but do not break.”

“Forever is composed of nows.”

“The race is not always to the swift...but to those who keep on running.” “The race is not always to the swift...but to those who keep on running.” ––Author UnknoAuthor Unknownwn

–Dorothy Broude

–Paul Pearsall

–Jean de La Fontaine

–Emily Dickinson

–Author Unknown

Proud to support individualsliving life in the moment.

B E XTR A . c om

64342_A.r2 2/10/05 2:20 PM Page 2

Page 3: Perform 3

FITNESS8 10 Innovative Ways to Exercise

You don’t need to set aside a big chunk of time—our “fitness bursts” will fit right into your daily routine.

22 Reflection in the MirrorHow to choose a health club that reflects your style and fitness goals.

GARDENING & NATURE10 Lake Tahoe: A Natural

American TreasureExplore its alpine beauty hiking hundreds of miles of new trails. Or treat yourself to a romantic lake cruise. There’s something foreveryone—fine cuisine, top-notch hotels, and a variety of indoor and outdoor activities.

FAMILY & LIVING15 Mission: Possible

Twenty years after becoming the first woman in space, Sally Ride has a new mission—to getother females interested in the traditionally malefields of math, science, and technology.

45 Your Monthly Money CalendarOur month-by-month to-do list shows you easyways to organize your finances.

TRAVEL & LEISURE25 Patriot Lanes

Wheel your way through American history on a bicycle trip through Jamestown, Williamsburg,and Yorktown, Virginia.

35 Grape Expectations: Virginia WinesCome of AgeEscape the ordinary with a wine-tasting tour of the up-and-coming vineyards of Virginia.

47 Festival GetawaysNo matter where your interests lie, there is probably a festival for you somewhere aroundthe country.

HEALTH6 Take the Treatment Challenge

Is your arthritis pain medication everything it should be?

28 The Doctor Is InPain Specialist Dr. Jeffrey Gudin answers important questions about arthritis.

42 Emerging from the Shadows of PainThe development of drugs that target the COX-2 enzyme has revolutionized the treatment of arthritis and other types of pain.

TIPS & TRENDS38 Bright Thinking

Optimists are not only happier, they’re healthier,too. Even better, they may live longer.

40 The Thrill of the GrillSpice up your summer with these simple but delicious barbecue recipes, which can be prepared in minutes.

THE LIGHTER SIDE52 Getting to Know You!

Our fun quiz will help you get to know yourself better.

Contents

10

From the EditorWelcome to PERFORM™. This magazine is dedicated to and written for people who want to live life to the fullest. If we had

a motto, it would be something Alexander Woolcott once said: “There is no such thing in anyone’s life as an unimportant day.” No matter who you are—whether you are a parent, an artist, a world traveler, or a volunteer—you want to be able to do what you wantto do, when you want to do it.

Because maintaining an active life is essential to good health, we have packed these pages with ideas and experiences to feed your imagination. From exploring the world around you by taking a bike trip through American history, to understanding the latest advances inpain medicine, to seeing how America’s first female astronaut has chosen to give something back to the community, we hope to show yousome innovative ways you may not have thought of to get the most out of your life, whatever your lifestyle, hobbies, or career may be.15

10

3535 47

1525

30

2222

25

47

3838

4040

4545

2828

COVER STORY30 THE PROS OF BEING CAAN

Legendary actor, free spirit, and dedicated fatherJames Caan still writes his own rules, and showsno signs of slowing down.

30

64342_A.r2 2/10/05 2:22 PM Page 4

Page 4: Perform 3

Joint pain can make it hard to perform many of the activities youenjoy. That’s why you must be clear with your doctor about howjoint pain affects your life. Just follow these three simple steps:

1 ANSWER THE TREATMENT CHALLENGE QUESTIONSTO THE RIGHT.Take a moment to think about how you now treat your joint pain. Then check the Yes or No boxes to the right.

2 SHARE THE RESULTS WITH YOUR DOCTOR.Tell your doctor if you’re not getting all the relief you need.

3 DISCUSS HOW YOU WILL TREAT YOUR ARTHRITIS JOINT PAIN.Your Treatment Challenge answers may suggest that it’s time torethink how you manage joint pain.

Are you hitting your arthritis joint pain hard enough? Take the Treatment Challenge now!

How many Yes answers did you have? If one or more, talk to your doctor today about options for controlling joint pain.

1 I could not effectively control my arthritis pain.

2 My arthritis pain seemed worse than usual.

3 My arthritis pain interfered with my ability to:a. walk on a level surface.b. go up or down stairs.c. bend over.d. get in or out of a car.e. get in or out of bed.f. perform light chores.g. perform heavy chores.

4 My arthritis pain interfered with my ability to:a. sleep.b. play my favorite sport(s).c. perform daily activities such as shopping.

HAVE YOU EXPERIENCED ANY OF THE FOLLOWING IN THE PAST MONTH? Yes No

Important Information. BEXTRA is not for everyone. Prescription BEXTRA should not be taken if you’ve hadallergic reactions to certain drugs called sulfonamides, aspirin or other arthritis medicines or if you’ve had aspirin-sensitive asthma or are in late pregnancy. It is not recommended if you have advanced kidney disease. Tell yourdoctor if you have kidney or liver problems. In rare cases, serious stomach problems such as bleeding can occurwithout warning. Tell your doctor right away if you develop blisters in the mouth or a rash, as it can be a sign ofa serious skin reaction that may be life threatening. If you experience other unusual symptoms while taking BEXTRA,tell your doctor immediately. The most common side effects are headache, abdominal pain, indigestion, upperrespiratory infection, nausea and diarrhea. Please see important Product Information on page 54.

For more information, calltoll-free 1-866-864-2600,

visit www.BEXTRA.com or mail the Get More Information card

between pages 50 and 51.

Please see important product information on previous page.

PERFORM 7

64342_A.r2 2/10/05 2:34 PM Page 6

Page 5: Perform 3

PERFORM 9

Exercise

F I TNESS

8 PERFORM

Exercise

F I TNESS

Plan a nature walk to aromantic spot at the beachor in the woods, and bringalong a picnic lunch. Thisis a fun activity that canhave great rewards.

Park your car at your last stop, not your first,

so you won’t be tempted to drive from one

spot to the next. If you end up loaded

with packages halfway through your

errands, make a detour to your car,

park the bags, then walk briskly

to the next store on your list.

Instead of taking the elevator,

use the stairs. Remember the

mantra, “One up, two down,”

meaning you should try to take the

stairs whenever you are going

up only one flight, or down two.

If you want to exercise, but can’t find a way to squeeze it into your busy schedule,don’t worry—you don’t really need to set aside a big chunk of time. Research shows that frequent, short bursts of exercise add up, and a bunch of fitness bursts give you almost

the same health and weight-loss benefits as one longer exercise session. With that in mind,PERFORM™ magazine has come up with some easy, innovative exercises that

can be incorporated into your daily routine—a few minutes at a time!

1 2Use those downtimes when you’re waiting

for a file to print, a Web page to load, or an

e-mail to arrive to push back from your

desk and stretch your muscles. Try a few

knee extensions. While sitting upright in

your chair, extend your left leg out as

straight as you can, pause for a few seconds,

and then return to your starting position.

Do ten or fifteen extensions with each leg.

Walk around the block asbriskly as possible. You’ll gainenergy, both physically andmentally, and do better work whenyou get back. At four miles perhour, you can burn a hundredcalories in fifteen minutes.

stre

tch

onl

ine 7Put on your dancing shoes.

At the next wedding, bar mitz-vah, or birthday party you

attend, get on the dance floorand move your body. An hour

of social dancing can burn 230to 390 calories, so get out there

and have fun!

get footloose

3energy boost

6If you don’t have a dog, maybe now’sthe time to get one—or offer towalk your neighbor’s. The neigh-bor will owe you a favor, andyou’ll burn plenty of calories,especially if the dog is young,speedy, and determined. Makesure to wear comfortable shoesand enjoy the fresh air.

8If you’re home alone on a rainyday and are looking for some-thing to do, head to the attic orbasement and do some useful“busywork.” Pack up books, maga-zines, or clothes to donate to thelocal library, hospital, or shelter.It’s a great way to help out yourlocal charities, and the light lift-ing will help with your goals toget moving.

10picn

ic time

5Tighten your gluteals (rear end muscles) anytimeyou’re stuck waiting—in the postoffice line, at the dentist’s office,wherever. You can do these sittingor standing, but if the personbehind you winks or grins, you

may be attracting more attentionthan you think.

squeezes

sub

tle

9Work out to your favorite TV pro-gram. Walk on a treadmill or ride anexercise bike while the program ison. If you don’t own this equip-ment, lie on the floor and do somestretching exercises on the rug.

Lie flat on your back and pull yourknee toward your chest, keeping your

head on the floor. Hold for twenty seconds. Repeat with the other knee.

4sh

op

till you d

rop

innovative ways to e x e r c i s e1010 walk a dog

wor

k the house

tvtraining

Be sure to check with your doctorbefore starting an exercise program.

64342_A.r2 2/10/05 2:35 PM Page 8

Page 6: Perform 3

PERFORM 1110 PERFORM

L a k e Ta h o e : A N a t u r a l A m e r i c a n Tr e a s u r e by Jodie Gould

64342_A.r2 2/10/05 2:35 PM Page 10

Page 7: Perform 3

Of all the states in the Southwest, Nevada has had thehardest time keeping up with the Joneses (you try com-peting with the Grand Canyon and the Tetons!). Sure,

it’s home to Las Vegas, one of the glitziest, most visited cities inthe country, but I believe that Lake Tahoe is the jewel in thecrown of the state. Long considered a playground for Reno res-idents and Californians (it straddles the California and northernNevada border), Lake Tahoe should be on every serious travel-er’s itinerary when exploring America’s natural treasures.

Tahoe has undergone some major renovations in order toevolve from a world-class ski resort with a smattering of casinosinto a destination for adventure and eco-tourism. For starters,some of the strip motels in the Stateline area that seemed incongruous amid the beauty of the lake have been replaced byhigher-end, more aesthetically pleasing accommodations such asthe Grand Summit Resort.

My husband and I visited in May, considered the “shouldermonth” between ski season and summer, and therefore the slow-est period for tourism. Coming from New York City, the absenceof crowds didn’t bother us a bit, and the weather, except for one day when it snowed, was sublime. A warm blanket of sunenveloped us when we stepped out of the shade, and the mildspring temperature was conducive to physical activities. Althoughsnow can fall in any given month, the Tahoe Basin enjoys 274sunny days annually. It was too early in the year to swim in the

Lake Tahoe

GARDENING & NATURELake Tahoe

GARDENING & NATURE

PERFORM 1312 PERFORM

lake, of course, which at an average depth of 989 feet is the thirddeepest in North America. Only in the summer will it warm up toa refreshing 68 degrees Fahrenheit. Residents also boast that thelake is 99 percent pure—an amazing statistic when you considerthe nearly two million people who visit its shores each year.

The new Tahoe Rim TrailOne of the best reasons to come to Lake Tahoe, aside from the

skiing, is to visit the Tahoe Rim Trail (TRT), to take in the eye-popping vistas from the ridgeline of America’s largest alpine lake.Prior to September 2001, only a small portion of the 150-mileridgeline that loops around the magnificent alpine lake was acces-sible to hikers, bikers, and backcountry explorers. You might feellike yodeling as you peek between the pines, firs, and aspens atthe snowcapped mountains, which look remarkably like theAlps—without the cheese and cowbells.

Our guides took us for a moderate hike on a well-marked path,pointing out the spring wildflowers and towering, 9,735-footMount Tallac in the distance. The TRT has no lean-tos, only onecampsite, and numerous well-marked trails to choose from, eachoffering spectacular vistas.

I was surprised to learn that the idea for blazing the TRT wasconceived as recently as 1977. It was the brainchild of U.S.Forester Glenn Hampton, who wondered why only 30 percent ofthe land in the area had been made into paths. Hampton, an avidhiker, set out to find other possible rim trail routes. He researchedthe pathways used by early pioneers, Basque shepherds, andWashoe Indians, the region’s original inhabitants. The Tahoe RimTrail Foundation was formed four years later to recruit volun-teers, raise funds, and galvanize local and national support forthe project.

Those wishing to trek the complete trail route should plan ontaking two weeks to do so, keeping in mind that the nights canbe cold and snow can fall at any time (you might even run into ablack bear or two). The best times to hike are early to mid-Julyfor wildflowers and September for spectacular fall foliage.

There is no need to register to hike the entire TRT, but you maywant to join the Tahoe Rim Trail Association, so you can becomea member of the Tahoe Rim Trail 150 Mile Club once you’ve fin-ished hiking the entire trail. You will be listed in the association’snewsletter and given a signed map to hang on your wall.

Thousands of people, from schoolchildren to the elderly, havevolunteered their time and physical labor to clear paths andmaintain the trail. If you’d rather put your money where yourmachete is, sections of the trail are available for adoption through the TRT “Adopt-a-Mile Program.” You can memorializea friend, family member, or business through a donation that willbe acknowledged by two trailhead kiosks and in brochures thatcover your adopted mile. You will also get a framed photographof your little slice of heaven.

Squaw Valley’s High CampLocated in North Lake Tahoe, a breathtaking half-hour drive

from the South Lake, is Squaw Valley, which became interna-tionally recognized as the site of the 1960 Winter Olympics. TheNorth Shore is more residential than the South and just as beau-tiful. Drive during the day so you can experience the vertigo-inducing switchbacks, which remind me of the scenic windingroads of the French Riviera. Be sure to stop off for a hike downto Emerald Bay, where you can stroll along the beach in front ofa Viking-style mansion built by a local socialite named LoraJosephine Knight. Mrs. Knight converted a small island (thelake’s only one) into a tearoom, where she entertained guests.Weather and vandalism have since worn away most of the tearoom, but a small turret remains.

Like South Lake Tahoe, Squaw Valley underwent a major ren-ovation, with the installation of another six-passenger chairliftand a thirteen-acre mountain village at the base, with 640 newmountain homes, as well as new shops and restaurants. In addi-tion to skiing, snowboarding, tubing, and other winter activities,you can enjoy year-round ice-skating at Squaw Valley’s Olympic-sized Ice Pavilion, tennis, rock climbing, and swimming. We tookthe cable car to the High Camp Health and Fitness Spa, locatedat 8,200 feet, and watched from the heated outdoor lagoon andhot tub as a group of skiers went on their last few runs of the season. During the summer, there is plenty of hiking, mountainbiking, golfing, and horseback riding, and there is a fireworksshow at High Camp on July 4.

Cruising the lakeNo trip to Tahoe is complete without at least one boat ride, so

when you’re not skiing, hiking, or gambling at the casinos, youshould be cruising around the lake. There are two major boats to choose from. One is the M.S. Dixie II, which offers breakfastand champagne brunch cruises from April to October and sunset dinner/dance and sightseeing excursions year-round. The boatlaunches out of Zephyr Cove Resort and RV Park, just four milesnorth of Stateline, Nevada, on Highway 50.

We took the three-and-a-half-hour sunset dinner/dance cruise toEmerald Bay, which included wine, a three-course dinner, and livemusic in the disco/bar area. We shoved off at seven o’clock witha tour group from England and several starry-eyed couples. Thisgave us about an hour of daylight to stroll on the upper deck andwatch the sun slip behind the Sierra Nevada Mountains. Forthose who prefer to stay inside, there are tables with views onboth sides and a wet bar.

The paddleboat takes you over to Emerald Bay, a cove of pinetrees, eagle nests, and Mrs. Knight’s castle. Although the food on board is nothing to rave about, the friendly staff, excellentband, and well-timed events make for a true pleasure trip.

The other, even larger cruise operation is run by HornblowerCruises and Events, which also operates out of San Francisco, Los Angeles, and San Diego. Like the Dixie II, the Tahoe Queenoffers a three-hour sunset cruise to Emerald Bay with wine, din-ner, and live music. Unlike the Dixie II, operators say it is a realpaddleboat in which the big wheels actually provide the source ofits movement. (Both boats have a glass bottom portion where youcan view the marine life below.)

Hornblower also offers family dinner cruises, a family EmeraldBay cruise where kids ride for free, a heritage tour of therenowned architectural sights in the region, a shuttle to SquawValley on the north side of the lake, and, for the ultimate in luxurious living, private charters.

We took a spin on the Paradise Hornblower, a dining yacht that accommodates weddings, business events, and parties with anywhere from two to two thousand guests. As I sat, cocktail inhand on the sun-kissed deck, watching my husband don the cap-tain’s hat and pretend to navigate through the silky blue waters,I allowed myself to imagine that the vessel was ours (“I am thequeen of the world!”), at least for the duration of the cruise.

A nugget of the Old WestIf you’ve never been to an Old West town, or you’re traveling

with children, take a day trip to Virginia City, a popular touristdestination forty minutes outside Lake Tahoe. This mining townoffers a nugget of the Old West, although it has sacrificed someof its historic charm to T-shirts, fudge shops, and western sou-venirs. Located in Seven Mile Canyon, also known as “The Hill,”you can see the Stillwater Mountains seventy miles to the east andthe Humbolts, twice as far away.

Stroll on the original boardwalk that runs through Main Street.You can see where the brilliant Mark Twain worked briefly as anewspaper reporter for the Virginia City Territorial Enterprise.Look for faded signs on the sides of buildings, such as the oneadvertising the newspaper, as the few unadulterated vestiges ofAmerica’s pioneer past.

Another historical landmark is the old Piper’s Opera House,and don’t skip the musty Mark Twain Bookstore, where you willfind an excellent collection of western books and an adorablelong-haired cat that will greet you at the door. On your way outof town stop off at Silver City, three miles down the mountain,which is older and more authentic looking than the commercial-ized Virginia City. Silver mines still dot the hilly landscape, andyou can see where the mountains have been whittled away bycenturies of prospecting.

For more information about the TRT, contact the Tahoe Rim Trail Association at (775) 298-0012, or visit its Web site at www.tahoerimtrail.org. To book a cruise on the M.S. Dixie II, call (775) 588-3508, or visit www.tahoedixie2.com. For Hornblowercruises and events, call (800) ON THE BAY, or visit www.hornblower.com.

Jodie Gould writes about travel, health, and popular culture for a variety of magazines.

64342_A.r2 2/10/05 2:36 PM Page 12

Page 8: Perform 3

Where to Stay When You‘re in Lake TahoeThe accommodations in Lake Tahoe vary from the tacky to

the wacky to plush casino hotels and rustic bed-and-breakfasts. Choose according to your personal style and checkbook.

Inn by the Lake

3300 Lake Tahoe Boulevard

South Lake Tahoe, Calif. 96150

(800) 877-1466; (530) 542-0330

www.innbythelake.com

This well-run, tastefully decorated inn trumpets its “rooms with a beautiful view,” andit is, in fact, located right across Highway 50 from the lake. Not all rooms have lakeviews, however, so ask for an upper floor with a view when you make your reserva-tion. The rooms have refrigerators and two-sink bathrooms, and the inn provides anoutdoor heated pool, whirlpool spa, washing machines and dryers, and a generous,complimentary continental breakfast in the garden room. In keeping with Lake Tahoe’s environmental consciousness, guests have the optionof reusing towels and sheets to conserve water and energy. During our stay, there was a lovely wine-and-cheese reception for those who wished to meet themanagement and their fellow guests. Rates range from $98 to $355 off-season and between $112 and $635 during high season. Special packages and group rates are available.

Fantasy Inn3696 Lake Tahoe BoulevardSouth Lake Tahoe, Calif. 96150(800) 367-7736; (530) 541-4200www.fantasyinn.com

Lovers will want to book a theme room in this hotel dedicated to romance! Couples can choose from various kitschy themes designed to cater to their particular fantasy. These include Arabian Nights (desert theme, with tiger-print carpet, five-foot whirlpool spa, a round king-size bed, and tent-style ivory drapes); the Tropical Treehouse (cozy island bungalow with tropical motif); Graceland

(the largest theme room,with a spacious sittingarea, heart-shaped spa,and bright red colorscheme); and Romeo &Juliet (a hidden castleretreat with classic bridaldecor). Many rooms comewith fireplaces, love seats,and refrigerators, and allhave ceiling-hung TVs. It isreally quite fun if you getinto the spirit of things.My husband and I stayedin the Penthouse, whichhas a sophisticated, ArtDeco decor. It had a work-ing gas fireplace thatwarmed up the room withthe simple flick of a switch,a sunken whirlpool bathtubthe size of a kiddie pool,

and a double jet shower. Mirrors surround the king-size bed and hover unself-consciously above the ceiling, and hanging plants and statues give the room a feeling of sensuous luxury. The hotel offers complete wedding packages with clergy, chapel ceremony, bou-quets, wedding photos, and other mementos for those tying the knot for the first timeor renewing their vows ($599 to $1,500). Room rates range from $159 to $771.

Tahoe Lakeshore Lodge & Spa930 Bal Bijou RoadSouth Lake Tahoe, Calif. 96150(800) 448-4577; (530) 541-2180www.tahoelakeshorelodge.com

The Lakeshore Lodge is easy to miss, as it is nestled between a Best Western hoteland Heidi’s restaurant, but that’s because it is located right on a lakefront beach. As a result, all rooms have a lake view, balcony, or patio; condos come with a fireplace and kitchen. The first-floor rooms give you easy access to the beach, butthere are no partitions separating patios. If you want privacy, book higher. Best of all is the on-site, full-service spa called Elements, which offers massages,body wraps, reflexology, facials, and other body- and spirit-renewing treatments,based on the principles of Ayurveda. After my hour-long massage, accompanied by soothing, New Age music, I felt as if I had truly been touched by an angel.Elements is open to nonguests as well. Rooms start at $119 and condos start at $199 (prices vary depending on the season).

Where to Eat in Lake TahoeThere is no shortage of restaurants in Lake Tahoe, ranging

from the casual to the formal. Here are some you might want to try.

Dory’s Oar Restaurant and the Tudor Pub1041 Fremont AvenueSouth Lake Tahoe, Calif. 96150 (866) 541-6603; (530) 541-6603www.celticcatering.com

One of the most charming restaurants in South Lake Tahoe, Dory’s Oar is a localfavorite, catering weddings, corporate events, and private receptions, as well as afrequent stop for visitors. Owners Keith and Jeannette Simpson have transported a piece of their native Surrey, England, to Lake Tahoe. The Simpsons should know athing or two about events—after all, they’ve catered for the British royal family andgovernment, and we all know how much fun that lot has! Having lived in London, I can vouch for the authenticity of the upstairs Tudor Pub,which comes complete with fireplace, beer mirrors, pints on draft, and a dartboard—the necessary trappings of any British pub worth its salt. It’s a great place to hang outwith friends (the no-smoking law in California makes it even better), and with peopleof all ages, including kids and seniors.On the main floor, you are treated to elegant dining by Executive Chef MichaelJacobson. In addition to an extensive wine list, the menu offers such dishes asMaryland crab cakes with tomato, fresh basil, and roast garlic relish; fruit de mer,shrimp, salmon, and sea bass with lemon butter served in a puff pastry; and rack oflamb with a Dijon mustard crust, served with a roast onion demi-glace.

Nepheles1169 Ski Run BoulevardSouth Lake Tahoe, Calif. 96150 (530) 544-8130www.nepheles.com

Since 1977, Nepheles has been serving top-notch California cuisine with daily fish,vegetable, and game specials. Its chef has created interesting food and sauce com-binations, all of which are beautifully presented and served by an enthusiastic staff. This is a jewel of a restaurant in an area that is just beginning to blossom in its culi-nary offerings. We had seared ahi with Asian plum sauce, mashed garlic potatoesand carrots, a house salad with fabulously fresh lettuce and feather-light dressing,and salmon with a sweet cream sauce, mixed vegetables, and artichokes.

Llewellyn’s Harvey’s Resort and CasinoU.S. Route 50Stateline, Nev. 89449 (800) 553-1022; (775) 588-2411

Supreme service and breathtaking views of the lake can be found in this formalrestaurant atop Harvey’s Casino in Stateline. It’s pricier than most of the restaurantsin the area, but worth it, especially if you are looking for a romantic setting and finedining experience. Guests are serenaded by a piano player, giving the restaurantanother touch of elegance. As evening approaches, any shades that are closed areceremoniously lifted to reveal a full view of the lake at sunset.

Sprouts Natural Foods Cafe3123 Harrison AvenueSouth Lake Tahoe, Calif. 96150(530) 541-6969

This was our favorite breakfast and lunch place in Lake Tahoe—we ended up eatinghere nearly every day, sometimes more than once. Locals, especially skiers, bikers,and other health-conscious types, go to Sprouts for their tuna burritos, hummusmelts, nachos, smoothies, tempeh burgers, and sandwiches piled high with red cabbage, red onion, avocado, Monterey Jack, and, of course, sprouts, all made withlow-fat dressings. Fresh-faced young staffers who are perky even in the face ofbustling lunchtime crowds run this extremely worker-friendly restaurant.

Mott Canyon Tavern & Grill259 Kingsbury GradeStateline, Nev. 89449(775) 588-8989

Another locals hangout that does abrisk lunch and after-work business,Mott Canyon has excellent salads(try the Cobb and crispy chickensalad), yummy fries, and a Mott melt(turkey, bacon, cheddar, tomato, andavocado on sourdough) for thosewith hearty appetites. There’s a bigfish tank inside, an enormous stonefireplace, and a bar that serves an array of beers on tap. We stopped off here on ourway to the Tahoe Rim Trail and enjoyed a relaxing lunch on the porch. If you want toeat at an outdoor table, it’s a good idea to arrive a bit before the noon rush.

14 PERFORM PERFORM 15

by Kim Byrum Skinner

Twenty years after becoming the first woman in space, former

astronaut Sally Ride still packs a room. Her accomplishments remain

standard book-report fare; her place in history is secure. So how, exactly,

is civilian life any less crowded for an unassuming American icon?

NASA

64342_A.r2 2/10/05 2:37 PM Page 14

Page 9: Perform 3

“I thought, if this is the main thing you get in return for beingfirst, she can have it!”

From that point on, Sullivan was perfectly content with herillustrious place in history as the world’s first female to walk in space.

Celebrity jeopardyOn the inherent celebrity that comes with being first, Ride’s

20/20 hindsight remains refreshingly honest. “Oh, I think every-body has to kind of just stumble his or her way through,” shesays with a knowing laugh. “It was probably equal parts honorand burden, and maybe more of an honor than a burden, actual-ly. It’s a small price to pay for getting to do what I’ve had achance to do.”

quite striking when you lookback on Earth from the van-tage point of space. Thataffects most astronauts, indifferent ways. I gained anappreciation that what wehave is really very, very frag-ile, and that it’s more impor-tant than I had realized to tryto protect it.

“Just about every astronautsays this, so it’s become a bitof a cliché now, but whenyou look back at the planet,you do not see borders sepa-rating the countries. Thoseare things—fabrications—that we’ve created. That’s notwhat you see when you lookdown from space.”

Sullivan‘s walk to remember

Speaking from the Center ofScience and Industry (COSI),the hands-on museum for kidsbased in Ohio, where sheserves as president and CEO,Sullivan, 52, shares the experi-ence of walking in space—an accomplishment that leavesRide playfully envious.

“It’s hard to describe,”Sullivan says. “You knowthe suit cold. It’s a technicalexercise with a time planthat you can do in yoursleep. But you’re crazy if youdon’t, now and then, letyourself mentally zoom backand take in where you reallyare as you’re doing it,because it’s extraordinary toget to be there. Not all of the four-hundred-plus peo-ple who’ve flown in spacehave gotten to do it, and it’spretty amazing.

“The real meaning unfoldsand takes shape later. You’reaware of it and bursts of itpop through, but it is not ‘siton the mountain transportedby ecstasy.’ You have thingsto do.”

Sullivan admits that at onetime she wished she had been

chosen to be the first woman in space.“I realized Sally was a superb choice. If it wasn’t going to be

me, I’d have picked her. But, yes, there was a little bit of me thatsmarted about it.”

She changed her mind when she saw just how much the mediaand the public invaded Ride’s life. In 1983, when Ride’s firstflight was diverted to California to land due to weather, it wasSullivan’s job to meet the throng of disappointed VIPs waiting tosee her in Florida.

PERFORM 1716 PERFORM

Mission: Possible

FAMILY & L IV ING

Well, people don’t always recognize me on the streetnow, and that’s a good thing,” jokes Ride, a pro-fessor of physics at the University of California,

San Diego, who welcomes the elbow room. Early last spring, just days from the twentieth anniversary of

her famous ride aboard Challenger flight STS-7, which made herAmerica’s first woman in space, Ride, who is now 53, was verymuch recognized. She was inducted into the U.S. Astronaut Hallof Fame—fittingly, the first woman so honored.

Shuttling across the countryThese days, Ride tours the country with the Sally Ride Science

Festival. Her earthbound mission is to spark young girls’ interestin the traditionally male fields of math, science, and technology.

“We’re trying to change the climate around girls in math, science, and technology. Girls who are thirteen years old don’treally think about engineers as female—yet. They tend to hearthe word engineer and associate it with, you know, some fifty-year-old with a pocket protector.”

Flanked by her former shuttle mate, Kathryn D. Sullivan—America’s first woman to walk in space—Ride awaits her audi-ence, which clamors for a front-row glimpse of the most celebrated American astronaut since Neil Armstrong. It’s as ifnothing has changed.

The ride of her lifeAt the time of her history-making flight, Ride captured the

imaginations of girls and young women nationwide, promptingGloria Steinem to hail her six-and-a-half-day orbit as “an impor-tant first, because…millions and millions of little girls are goingto sit in front of the television set and know they can becomeastronauts after this.”

Selected from a field of seven thousand men and a thousandwomen, Ride’s flight-clinching advantage was her experiencewith NASA’s remote manipulator system, or RMS, a boom fiftyfeet long and the diameter of a telephone pole, used to fetch andretrieve satellites. During her flight, she deployed communica-tions satellites, operated the robot arm, and conducted experi-ments in materials, pharmaceuticals, and remote sensing of the Earth.

“Looking back, I’m actually proud of the way I handledthings,” Ride reveals. “It was really important to me to be seenas a competent professional. That’s really the principal image I wanted to put out there, because I thought it was a very important thing for all the women who were watching me, andall the girls growing up. I’m proud of that.”

Ride’s most important space discovery was to view life througha wide-angle lens.

“The main thing I was taken aback by and left with was theperception that we live on a planet—that we all live on a plan-et—and that this planet’s all we’ve got,” Ride says. “It really is

We’re trying to change the climate aroundgirls in math, science, and technology.Girls who are thirteen years old don’t reallythink about engineers as female—yet.

”“

NASA

Mission: Possible

FAMILY & L IV ING

NASA

Ride at the controls

Kathryn Sullivan

NASA

Kathryn Sullivan and Sally Ride

64342_A.r2 2/10/05 2:40 PM Page 16

Page 10: Perform 3

Mission: Possible

FAMILY & L IV ING

Completed in 1984 during Challenger mission STS-41G(Ride’s second flight), Sullivan’s three-and-a-half-hour space-walk generated much less spectacle, in part because space flightwas becoming, in the eyes of the public, much more routine.Nothing was farther from the truth. As evidenced by the loss ofboth Challenger (1986) and Columbia (2003), space travelremains high risk.

“At the end of the day, it’s just human beings. Two-footed, carbon-based life forms, highly fallible,” Sullivan says. “You putsome groups of human beings together in a room and it’s a miracle they can get the mail delivered on time. You put othergroups together and they get to the moon and back.”

“It’s a research and development program,” Ride agrees. “It’snot as routine as the news media might lead you to believe these days.”

Sullivan’s successful extra-vehicular activity led to a spot on the crew of Discovery STS-31, which deployed the Hubble SpaceTelescope in 1990. She left NASA in 1992 to become chief scien-tist at the National Oceanic and Atmospheric Administration,and she now calls COSI home.

“Sally and I have never sat down over a beer and comparednotes, but I suspect she approached most things before her flightthe same way that I did,” Sullivan says. “This was my first spacewalk, no matter how many people did it before me.

“The only humans who’d done space walks were all guys, butI didn’t spot anything I thought was going to be magically differ-ent because of our anatomy. I’d never noticed that airplanes orships worked differently because of the gender of the person atthe helm.”

Support structureAsked how she raised such a family of overachievers, Ride’s

mother, Joyce, once responded, “In a way, you could look at it asneglect. Dale and I simply forgot to tell them there were thingsthey couldn’t do. But if it had occurred to us to tell them, weprobably would have refrained.”

PERFORM 19

Mission: Possible

FAMILY & L IV ING

18 PERFORM

I haven’t quite reached the point where I‘mlooking back on my life and thinking about it all—yet. I think that‘s good,” Ride says,laughing. “I‘m certain it will happen some-day, but I really haven‘t tried to step backand think about, you know, my place in history,or the ultimate meaning of my flight.

”“

Sally Ride

NASA

NASA

Ride and Sullivan rely on a hearty sense of humor to keep life’sdemands in perspective. Presented with Oprah Winfrey’s signatureclosing question, “What do you know for sure?” Ride’s partingwit doesn’t disappoint.

“Uh, E equals MC squared?” she quips. “Beyond that, not much.”

Her mother’s remark catches Ride pleasantly off guard.“You know, that’s totally true,” she says excitedly. “That quote

is accurate. Neither of my parents ever told either me or my sister (a Presbyterian minister) that we couldn’t do something. It’s totally amazing, especially since, in my case, neither of them were scientists or engineers.Neither of them were technical professionals. And here they werewith this daughter who was inter-ested in science, and they proba-bly couldn’t quite figure out howthat happened!”

What does she consider her parents’ greatest gift? Withoutquestion, her self-esteem.

“I didn’t have any role modelsgrowing up, other than my parents and a couple of teachers,”Ride adds. “I really didn’t haveanyone out there in the real worldI emulated—you know, scientistswho were really role models forme. Certainly no astronauts. Lotsof people I respected, but no onethat I would have considered arole model.”

Reflecting on achievement

“I haven’t quite reached thepoint where I’m looking back on my life and thinkingabout it all—yet. Ithink that’s good,” Ridesays, laughing. “I’m cer-tain it will happensomeday, but I reallyhaven’t tried to stepback and think about,you know, my place inhistory, or the ultimatemeaning of my flight.”

Given their publicachievements and high-powered lives, both

Sally Ride today

NASA

NASA

64342_A.r2 2/10/05 2:40 PM Page 18

Page 11: Perform 3

20 PERFORM

More onSally Ride‘sorganizationsTO JOIN THE SALLY RIDE CLUB:

www.SallyRideClub.com

Phone: (858) 638-1432

e-mail: [email protected]

To join the Sally Ride Circle as a

parent, educator, corporate, or civic

leader, or to support Imaginary

Lines as a partner or sponsor,

address inquiries to:

9171 Town Centre Drive

Suite 550

San Diego, Calif. 92122

Phone: (858) 638-1432

e-mail: [email protected]

MORE ON THE CENTER OF

SCIENCE AND INDUSTRY:

For information, or to support,

shop at, or visit either COSI

hands-on learning center, contact:

COSI Columbus

833 West Broad Street

Columbus, Ohio 43215

Phone: (888) 819-COSI;

(614) 228-COSI

www.CosiColumbus.org

COSI Toledo

1 Discovery Way

Toledo, Ohio 43604

Phone: (419) 244-COSI

www.CosiToledo.org

Kim Byrum Skinner is an Ohio-based freelance writer.

NASA

ARE YOU READY TOCHALLENGE

THE JOINT PAINOF ARTHRITIS?

BEXTRA. Powerful 24-hour relief. One tablet. Once daily.

Ask your doctor if a FREE sample of BEXTRA is right for you.

One 10-mg BEXTRA Tablet, once a day, provides the kind of 24-hour relief many arthritis sufferers are looking for.Prescription BEXTRA is tough on joint pain and inflammation. And there’s one convenient dose that’s powerfulenough to tackle both the pain of osteoarthritis and adult rheumatoid arthritis.For more information call 1-866-864-2600 or visit www.BEXTRA.com.Important Information. BEXTRA is not for everyone. Prescription BEXTRA should not be taken if you’ve hadallergic reactions to certain drugs called sulfonamides, aspirin or other arthritis medicines or if you’ve hadaspirin-sensitive asthma or are in late pregnancy. It is not recommended if you have advanced kidney disease.Tell your doctor if you have kidney or liver problems. In rare cases, serious stomach problems such as bleedingcan occur without warning. Tell your doctor right away if you develop blisters in the mouth or a rash, as it canbe a sign of a serious skin reaction that may be life threatening. If you experience other unusual symptomswhile taking BEXTRA, tell your doctor immediately. The most common side effects are headache, abdominal pain,indigestion, upper respiratory infection, nausea and diarrhea. Please see important Product Information on page 54.

64342_A.r2 2/10/05 2:46 PM Page 20

Page 12: Perform 3

Choosing a Health Club

F I TNESSChoosing a Health Club

F I TNESS

Pilates is an exercise program that works every

muscle in the body in an aware, efficient manner.

It is a series of exercises that are similar to yoga but

involve more fluid, controlled, and concentrated

movement. Pilates improves strength, flexibility,

balance, control, and muscular symmetry. The rhythmic

exercises promote elongated and toned muscles,

and are noted for strengthening the abdomen, lower

back, and buttocks, promoting a strong body core.

Step aerobics provides a high-intensity, fat-burning

workout and is lower impact than the jumping

up and down found in other forms of aerobics.

what they call “express workouts”. Others may stress personaltraining, group classes, or a wide variety of equipment. Some aresocial; others expect you to work out and go.

There is no “best” club—the best club for you is the one you’llwant to attend regularly. A club membership will work for you only if you feel at ease there and want to show up. Here is

some expert advice on how to pick a clubthat reflects your style and goals:

• Make a list of what you want from a fitness club, including equipment, location,look and feel, variety of classes, personaltrainers, cleanliness, and cost.

• Which clubs are close to home or work? It won’t do you any good to join a club on the other side of town if you won’t go. Be

sure the location and hours fit your needs. Studies have shownthat if you live or work within a fifteen-minute drive, you’re morelikely to go frequently.

No matter where you live, your area most likely has fitnessclubs, health classes, personal trainers, and activities that canmove you toward your fitness goals. Whether you like to exercisealone or in a group, joining a health club can help you make exer-cise a habit, and you can make new friends—people who shareyour desire to get into shape. The PERFORM™ fitness pro hasdone the legwork to help you choose a health club, soall you have to do is get out and get on the move.

Clubs vary widely in the equipment, classes, activi-ties, and services they offer, so choosing the right onemight mean the difference between making fitness ahabit and not going at all. Almost all have a varietyof cardio (for the heart) equipment, such as tread-mills, elliptical trainers, and stair machines, and mostoffer popular group exercise classes such as spinning,yoga, step aerobics, and Pilates. But outside of these, each clubhas a different atmosphere, customer base, and services. Someclubs focus on people who exercise during the workday and offer

Step AerobicsPilates

REFLECTIONIN THE

MIRROR

How to choose a health

club that reflects your

style and fitness goals

by Joan Price

There is no “best” club–

the best club for you

is the one you’ll want

to attend regularly.

22 PERFORM PERFORM 23

Be sure to check with your doctor before starting an exercise program.

64342_A.r2 2/10/05 2:46 PM Page 22

Page 13: Perform 3

PERFORM 25

T he sharp odor of pitch pine hangs in the air, alongwith distant echoes of an unseen woodchopper. The quiet stands of cypress and pine envelop you,

and the settlement of Jamestown falls away as you delvedeeper into the woods of the small Virginia island where a

new world was born.

Suddenly, the crunch of tires on a paved road breaks yourreverie. The imaginary sights, sounds, and smells of ColonialAmerica vanish into the twenty-first century, where you’re pedalinga twenty-three-mile scenic parkway spanning three American

originals: Jamestown, Williamsburg, and Yorktown—representingthe beginning, middle, and end of the Colonial period.

Biking Virginia’s National Park Service–administered ColonialParkway blurs the line between past and present and offers the chance

to slip between the two as you pedal through history.

Begin at Historic Jamestowne, the site of the first English settlement inthe new world, and end at Yorktown Battlefield, site of the British surren-

der that ended the Revolutionary War 175 years later. In between, witnessnearly two centuries of early American history and a stretch of scenic parkway

that skirts the expansive James and York rivers and passes right throughColonial Williamsburg.

Historic Jamestowne Recent discoveries of the James Fort and the remains of a seventeenth-

century colonist have brought new attention to this national park.Despite some damage from Hurricane Isabel in 2003, Jamestown

Island remains a wooded sanctuary offering a cycling tourvirtually undisturbed by traffic. Large oil paintings

along the roads tell the story of the harsh colo-nial life the English settlers encountered.

by Mary Burnham

Biking a Time Line on

Virginia’sColonial

Parkway

Biking a Time Line on

Virginia’sColonial

Parkwaytrainers, and stair machines, and most offer popular group exer-cise classes such as spinning, yoga, step aerobics, and Pilates. Butoutside of these, each club has a different atmosphere, customer

base, and services. Some clubs focus on peoplewho exercise during the workday and offer whatthey call “express workouts”. Others may stresspersonal training, group classes, or a wide vari-ety of equipment. Some are social; others expectyou to work out and go.

There is no “best” club—the best club for youis the one you’ll want to attend regularly. A clubmembership will work for you only if you feel at ease there and want to

show up. Here is some expert advice on how to pick a club that

No matter where you live, your area most likely has fitness clubs,health classes, personal trainers, and activities that can move youtoward your fitness goals. Whether you like to exercise alone or ina group, joining a health club can help you makeexercise a habit, and you can make new friends—people who share your desire to get into shape. ThePERFORM™ fitness pro has done the legwork tohelp you choose a health club, so all you have to dois get out and get on the move.

Clubs vary widely in the equipment, classes,activities, and services they offer, so choosing theright one might mean the difference between mak-ing fitness a habit and not going at all. Almost all have a varietyof cardio (for the heart) equipment, such as treadmills, elliptical

Spinning is an aerobic exercise that takes place

on a specially designed stationary ”spinning” bicycle.

As you pedal, motivating music plays and the instructor

talks you through a visualization of an outdoor

cycling workout. During the class you vary your pace—

sometimes pedaling as fast as you can; other times

cranking up the tension and pedaling slowly from

a standing position. This helps you to focus inward

and work on your mind as well as your body.

Choosing a Health Club

F I TNESS

Yoga seeks to promote health and well-being through

physical exercise. It controls the activities of the mind, and

its methods include ethical disciplines, physical postures,

breath control, and meditation. Many common physical

ailments can be improved through the regular practice

of yoga, and it is never too late or too early in life

to take it up. Anyone can do it.

Yoga Spinning

24 PERFORM

Once you join, go!

Make a commitment

to a regular

workout schedule.

Page 14: Perform 3

PERFORM 27

Patriot Lanes

TRAVEL & LE ISURE

After a nine-day siege by American and French troops underGeneral George Washington, the British surrendered Yorktownon October 18, 1781. It was the last major battle of the War forIndependence. Preserved here are Surrender Field, the siege anddefense lines of the Americans and their French allies, and theBritish, as well as the house where terms of surrender were ironedout. The Moore House is open weekends in the spring and falland daily in summer.

Yorktown offerstwo road tours: the battlefield tour,seven miles andmarked with yellowarrows; and the red-arrowed encamp-ment tour, ninemiles and less heav-

ily traveled. Markers, earth-works, and displays tell thestory of the siege.

From the site of Washington’sheadquarters on the encamp-ment tour, bikers can access theadjoining 8,000-acre NewportNews Park, and another five-mile dirt bicycle trail throughwoods. The park has camping,hiking trails, a lake, and otherrecreational opportunities.

The British surrender ofYorktown was the symbolicending to the Colonial period,and it is a fitting place to endthis historic bicycling tour.

PERFORM 27

Mary Burnham is coauthor of Hiking America Virginia and Exploring the Small Towns of Virginia and Maryland.

26 PERFORM

Patriot Lanes

TRAVEL & LE ISURE

26 PERFORM

you’ll see the Magazine, a round brick building that signals thebeginning of the historic area. Motor vehicles are not allowedinside, but bikes are. Take some time exploring this re-createdthree-hundred-acre town, including eighty-eight original build-ings. A ticket is required to enter most of the buildings, except forthe Colonial Williamsburg taverns and retail shops.

Colonial Williamsburg, or “Middle Plantation”, as it wascalled, grew from a defensive outpost established in the early daysof Jamestown into a thriving settlement. In 1698, officials movedthe Virginia colony’s capital from the then-swampy, bug-infestedJamestown Island to Williamsburg.

Francis Nicholson, the royal governor, took on the task of laying out the new town around the College of William and Mary and the few homes and shop buildings. Thanks to suchearly planning, Williamsburg’s streets are arrow straight andwide. The main thoroughfares are paved, while some side streetsare gravel and crushed oyster shells.

When you’re ready to leave, find Robertson’s Windmill and follow a dirt path to the visitor center. Here begins the thirteen-mile journey to Yorktown. This is a less-traveled section of theparkway, with fewer scenic overlooks. Terrain is rolling andmostly wooded as it follows a log palisade, or protective fence,built by colonists across the entire width of the Virginia peninsula.

About six and a half miles from Williamsburg, the parkwayabruptly opens out onto the York River. From these shores you’llsee Cheatham Annex, an extension of Naval Station Norfolk,and farther down the road, the Naval Weapons Station. Today’snavy takes advantage of the York River’s deep channel, just asBritish General Cornwallis did when he made Yorktown his basein 1781. Historic markers are all that’s left of old plantations andIndian villages that once graced these shores.

Yorktown BattlefieldAt the intersection of Ballard Street, begin looking for mounds

of earth on either side of the road. British soldiers built thesedefensive breastworks during the Revolutionary War, andConfederate soldiers strengthened them eighty years later.

From here, signs direct you to either the visitor center or thebattlefield. The former is a good starting point for this historicpark, and a stopping place for restrooms and water.

PHO

TO

GR

APH

SC

OU

RT

ESY

OF

TH

EC

OL

ON

IAL

WIL

LIA

MSB

UR

GFO

UN

DA

TIO

N, W

ILL

IAM

SBU

RG

, VIR

GIN

IA

The imaginary sights, sounds, and smells of Colonial America vanish into the twenty-first century, where you’re pedaling a twenty-three-mile scenic

parkway spanning three American originals: Jamestown, Williamsburg, andYorktown—representing the beginning, middle, and end of the Colonial period.

Biking Conditions Elevation: The terrain is virtually flat along the James and York rivers, and slightly hilly between, with an elevation range from one to twenty-five metersabove sea level.Traffic: The speed limit is forty-five miles per hour and no commercial traffic is allowed on the parkway. There are no intersections; roadways are elevated over the parkway. Bicycles are not allowed in the tunnel that passesbeneath Colonial Williamsburg. In keeping with the natural scenery of the park-way, there are no lines or shoulders, so be careful to keep to the right and ridein single file.The ride: The pavement of aggregate stone cast in concrete makes for a slight-ly bumpy ride. Be careful of the joints between the large panels of concrete.Skinny tires can get caught in them. Distance markers are in kilometers andbegin in Yorktown.

ServicesThere are no service stations, restrooms, or water sources along the parkway. Fill water bottles at the visitor centers in Jamestown or Yorktown,or in Williamsburg, halfway between. Each has restrooms.Camping: At the Jamestown end is Jamestown Beach Campsites, just off Route 31. Take Route 614 from the parkway for two miles. Open year-round.(757) 229-7609.Newport News Park, adjacent to the Yorktown Battlefield, also has camping.Open year-round. (757) 888-3333.Parking: Park at any of the three visitor centers, but at Yorktown andJamestown you will have to pay the admission fee. Free parking is available atthe Powhatan Creek parking area, just before the Jamestown Island entranceon the left. No overnight parking is allowed here or within either park.

When to GoCrowds and traffic are thickest May through September. The average summertemperature in Virginia is around eighty degrees, but high humidity makes it seem hotter. Breezes off the James and York rivers provide some relief,though. The average winter temperature is 45 degrees, with light snow inJanuary and February.

Getting ThereNewport News/Williamsburg Airport is twenty minutes away; RichmondInternational Airport is forty-five minutes; and Norfolk International Airport is onehour. Amtrak has a train station in Williamsburg. By car, take Interstate 64 to exit 242A. Go six miles west on Route 199, four miles south on Route 31, thenleft on Route 359 south. Pass the Jamestown Settlement and proceed to theColonial Parkway. Directly across the parkway is the Powhatan Creek parkingarea. The Jamestown Island entrance station is to the right.

Admission and HoursHistoric Jamestowne: $8 for adults (16 and under free); good for seven days.The entrance is open daily from 8:30 A.M. to 4:30 P.M. Once inside, visitors and bikers can stay until dark. A new visitor center is under construction,with completion planned for Jamestowne’s four hundredth anniversary in 2007. Meanwhile, a temporary modular visitor center is open from 9:00 A.M.to 5:00 P.M.Yorktown Battlefield: $5 for adults (16 and under free); good for seven days.The visitor center is open from 9:00 A.M. to 5:00 P.M.; the tour roads and battlefield are open from sunrise to dusk.Combination tickets: A $10 pass is good for seven days at both Yorktown and Jamestown.Colonial Williamsburg: There is no charge to walk or bike through the streetsof Colonial Williamsburg. Passes can be purchased to enter the historic buildings. Open daily from 9:00 A.M. to 5:00 P.M.

More InformationColonial National Historical Park(757) 898-3400www.nps.gov/colo

Colonial Williamsburg(800) HISTORYwww.colonialwilliamsburg.org

Williamsburg Area Convention and Visitors Bureau(800) 368-6511www.visitwilliamsburg.com

Two circuit tours, one three miles and the other five, offer vistas of the James River through marsh and quiet woods that,thanks to preservation, have returned to a state resembling whatthe colonists first saw.

Jamestown dates to 1607, when three tiny ships — the SusanConstant, the Godspeed, and the Discovery — brought the 144settlers who established the first permanent English-speaking settlement in North America. Settlement ruins are fragile, so bicycles are not allowed within the Old Town site itself. Leavethem at the bike rack in the parking lot and walk across the footbridge into seventeenth-century life.

A short walking tour takes you by thefoundations of these early structures,including the James Fort, rediscovered 370years after it was built. Until recent years,archaeologists believed the fort had beeneroded by the James River.

Pedal off the island and follow theColonial Parkway past swampland, standsof marsh grass, sandy riverside beaches, andan occasional dairy farm. Chances are goodof seeing a great blue heron or snowy egretalong the banks or shallow shoreline of theJames River. Every mile or two brings a

scenic overlook with markers describing the history of the area.The views of the expansive James — called Powhatan by theIndians — are breathtaking here, as it approaches the end of a 340-mile journey from the Appalachians to the Chesapeake Bay.

As the parkway pulls away from the James, the terrainbecomes more rolling and hilly. At eight miles, there’s a greatpicnic spot beneath towering white oak trees, described by amarker as dating back to 1750.

WilliamsburgAt nine miles, the parkway tunnels one third of a mile

beneath Colonial Williamsburg. Bicycles are not allowed in the tunnel and should exit at the off-ramp where directed. Don’t despair. The detour takes you right through the heart ofColonial Williamsburg.

At the top of the exit ramp, turn left onto Newport Avenueand take the next left onto South England Street. After one block

Page 15: Perform 3

PERFORM 2928 PERFORM

the doctor is inThe Modern Management

of Arthritis Pain

the doctor is in

Q: What are the most common types of arthritis, and howdo I know if I’m treating my joint pain correctly?

A: Osteoarthritis (ahs-tee-oh-arth-RYE-tis), or OA, is themost common. Millions of people in the United Stateshave it. In OA, the cartilage that covers the ends ofbones in the joint wears down. In time, bone begins torub against bone. This often leads to:

• Pain

• Loss of movement

Rheumatoid arthritis (roo-mah-toid arth-RYE-tis), orRA, is one of the most serious and disabling types. It affects women more than men. In RA, the body’s ownimmune system attacks the joint. The joint lining getsinflamed, causing:

• Soreness

• Stiffness

• Aching

If you have pain, stiffness, or swelling in or around ajoint for more than 2 weeks, see your doctor. Symp-toms can come on fast or slowly. Only a doctor can tellif it’s arthritis.

Q: I like running, but joint pain in my hips and knees hasreduced the enjoyment I get out of this exercise. Whatadvice do you have?

A: The right exercise can help you stay active. The key is toavoid excess stress on your joints. You may not be ableto run if you have bad joint pain in your knees or ankles.If this is the case, try a new exercise for a change.

Have you tried biking? Make sure the bike is the rightsize for your body. It should have a soft, padded seat.Make sure your seat and pedals are the right height. Try using lower gears on your bike to reduce the impactof pedaling. A good bike store can help you with this.

Not a biker? Swimming is also a great way to keep flexible and it’s easy on the joints. Talk with your doctor about what is right for you.

Q: I’ve heard conflicting opinions on whether exercisewill help reduce my joint pain. What medical advice doyou have about staying active?

A: Exercise is vital in dealing with arthritis. Starting canseem like a huge task. Try to start slow and make itfun. Begin with stretching to improve your range ofmotion. This will help make daily tasks easier to do.Once this becomes easy, you can move on. Addweights, yoga, or biking.

What if you’re in too much pain? You may want to trya water program. Being in water lessens stress on yourhips, knees, and spine.

Exercise also has many benefits that include:

• Easing joint pain and stiffness

• Building strong muscle around the joints

• Increasing flexibility and stamina

• Helping you sleep better

• Controlling your weight

• Reducing the risk of health problems, such asosteoporosis and heart disease

It’s best to ask your doctor what is right for you.

Are your days free from joint pain? Formany adults, enjoying their day dependson their joint pain. There are good daysand not-so-good days. PERFORM™

offers advice from our medical expert,Jeffrey Gudin, MD, to help get you backto living life as you want to.

In this issue, Dr. Gudin answers common questions peo-ple have about joint pain. Dr. Gudin is clinical director ofthe Pain Management Center at Englewood Hospital andMedical Center. It is part of Mt. Sinai University Schoolof Medicine in Englewood, New Jersey. Dr. Gudin isboard certified in both pain management and anesthesiol-ogy (giving anesthesia for surgery). He has helped manyarthritis sufferers lead healthier, more pain-free lives.

Q: Simple motions like stirring food when I cook tend tomake the joints in my hands and wrists feel weak andsomewhat painful. Is this common, and is there anyway I can reduce this joint pain?

A: The stiffness, pain, and swelling of arthritis can reallyreduce the range of motion in all joints. This is thenormal distance joints can move. However, not beingactive due to pain can in turn lead to muscle loss andweight gain. It’s best to try to stay active and close toa healthy weight. This will help relieve pressure thatcan damage your joints.

Exercise should be part of your complete treatmentplan. It can improve:

• Joint mobility • Muscle strength • Overall physical health

Medications will also help control joint pain. And withthe right exercise, they can help relieve pain and fatigueand protect the joint. You and your doctor can come upwith a program to reduce joint damage and promoteoverall health.

Q: I’ve been taking the same generic pain reliever for myarthritis joint pain for years. Is there anything new forarthritis pain that may help me?

A: Pain relief has come a long way. You don’t need to suf-fer from pain and swelling. Many options are on hand.There are over-the-counter drugs such as acetaminophen(ah-see-tuh-MIN-uh-fen) and ibuprofen (EYE-byu-pro-fen) and prescription drugs such as COX-2–specificinhibitors (Celebrex and BEXTRA are examples). In somecases, surgery is needed. Diet and exercise are also impor-tant. Your doctor may discuss some of these optionswith you.

Which joints does arthritis affect?

Arthritis affects the knees, hips, ankles, elbows, hands, and spine (both neck and back). It can be caused by:

• Redness and swelling within the joint

• Damage from trauma or pressure against the joint

It can often lead to other things, such as:

• Fatigue that can make the pain harder to bear, making it seem much worse

• Depression from not being active, or from no longerbeing able to do activities you enjoy

How do I know if I have arthritis?

You might suspect you have arthritis if you have symptoms that include the following:

• Persistent joint pain

• Pain or tenderness in a joint that is aggravated by any movement or activity, such as walking, getting up from a chair, writing, typing, holding an object,throwing a ball, or turning a key

• Joint swelling, stiffness, redness, and/or warmth

• Loss of flexibility or range of motion in a joint

• Joint deformity

• Crepitus (the cracking noise arthritic joints make upon movement)

Your doctor can diagnose arthritis by looking at your medical history, doing a physical exam, ordering tests, and having x-rays taken.

Information in this article should not replace talking with your doctor about your health.

64342_B.r3 2/10/05 2:54 PM Page 28

Page 16: Perform 3

PERFORM 31

best remembered for his mesmerizing performance as SonnyCorleone in Francis Ford Coppola’s legendary Godfather series.But ask him what he’s proudest of, and his answer may surpriseyou: “I think my proudest achievement is that I’ve never misseda day’s work in my life,” he says.

Raising the barIt’s hard for most of us to imagine attaining such an impressive

career—let alone not missing a single day of filming on countlesssets and locations. But for Caan, who learned the value of team-work and commitment from playing organized sports in hisyouth, it’s no big deal: “You sign on and you finish,” says Caanwith his matter-of-fact delivery. And as for the people he’sworked with, “You don’t have to work with them again, but youhave to finish the season. You can’t quit.”

Throughout his career, Caan has displayed an unstoppablework ethic and an unwavering dedication to whatever projecthe’s involved with. Born in the Bronx and raised in Queens, NewYork, Caan says his work ethic was inspired by his father, whooperated a successful meat business. What was his main inspira-

tion for going into acting? “I didn’t want to lug hindquarters ofbeef all day,” says Caan in his typical tell-it-like-it-is fashion.

Caan’s free-spirit attitude toward life was evident early on. Hespent a year at Michigan State University, where he played foot-ball with the Spartans, and then transferred to Hofstra Universityon Long Island, New York, initially to study law. He eventuallychanged his major to drama after a successful audition at SanfordMeisner’s Neighborhood Playhouse during a spring break.“When I got back, [acting] was sort of like a last resort. I went toschool and hammered out my interests, and acting has continuedto hold my interest actually until now.”

One of Hollywood’s mostversatile actors

In addition to playing football, Caan has a black belt in karate,and spent nine years as a professional rodeo cowboy. So it’s natu-ral that Hollywood looked to him to fill the roles of “tough guy”—especially after the landmark Godfather movies: “After I did Sonny[Corleone], every script I got there had to be twelve people dead bypage twenty or I wouldn’t get it,” he says with a laugh. “But thenI did Funny Lady and For the Boys, and they go, ‘We never knewyou could sing and dance.’ Well, nobody ever asked me!”

Caan enjoys playing the tough-guy roles that suit him so well.But he also knows that to stay in demand, you have to be able toperform well in as many things as possible. “If you’re going to be

James Caan

COVER STORY

a saxophone player, you have to learn how to play a lot of dif-ferent songs to be considered a good player. You can’t just play“Yankee Doodle Dandy” all the time. You know what I mean?”

“Time out” for fatherhoodAfter years of having phenomenal success and enjoying the

Hollywood actor lifestyle, Caan lost his sister and best friend,Barbara, to leukemia in 1981. This tragedy made Caan reflect onhis life, leading to a decision that would add to his legend. Hedecided to leave Hollywood in order to spend time raising hisfamily. “I decided that, unless I had passion for something [act-ing], I wasn’t going to do it. So I basically quit.”

As a father, Caan excels. He revels in the fact that he’s been ableto have a positive impact on the development of his children,including daughter Tara, 39, and sons Scott, 27 (also a successfulactor), Alex, 12, Jimmy, 8, and Jake, 5. He perks up when he dis-cusses his role in coaching his sons’ sports teams. “You see thechanges happening from day to day and your influence. I thinkthat’s why I enjoy coaching so much, too. Take a kid who didn’tthink he could do something and in five minutes’ time have himdoing it, and all of a sudden he goes from a shy little kind of ascaredy-cat to a little banty rooster. Creatively, it’s quite reward-ing, you know?”

Caan also enjoys seeing the results in real time: “You don’t haveto wait six months for them to put music to it and edit it—thingshappen right in front of your eyes.” When asked who he turns towhenever things get tough, Caan immediately points to his chil-dren: “I look to them...they’re the ones who lift me up.” Clearly,playing father is a role Caan is very keen on. When asked whatkeeps him going, Caan answers with trademark honesty andhumor: “What keeps me going? Four wives and five children!”

Some “choice” bits• Turned down lead roles in Mash, The French

Connection, One Flew Over the Cuckoo's Nest,and Apocalypse Now

• Favorite on-screen role: The professional safecracker,Frank, in Thief

• Favorite off-screen role: Dad

“I decided that, unless I had passion for something,

I wasn’t going to do it.”

“Take a kid who didn’t think hecould do something and in fiveminutes’ time have him doing it.Creatively, it’s quite rewarding.”

30 PERFORM

James Caan

COVER STORY

After a brief absence from the limelight, Oscar-, GoldenGlobe-, and Emmy Award nominee James Caan is nowback as the star of the new hit NBC TV series “Las

Vegas” and hit film Elf. The dedicated actor took a few momentsbetween takes on the set to tell PERFORM™ what drives him tosucceed, how he stays in the game, and how he places his role asa father above all else.

James Caan, known as “Jimmy” to friends and fans alike, hasappeared in more than seventy feature films. These include cul-tural and critical landmarks such as A Bridge Too Far, For theBoys, Funny Lady, Honeymoon in Vegas, Misery, Rollerball,The Gambler, The Way of the Gun, and Thief. Of course, he’s

CaanCaanby Jeff Mucciolo

ThePros of Being

Film legendJames “Jimmy” Caan

went from humblebeginnings in Brooklyn

to the heights ofHollywood success.

After taking time off tobe with his family, this

real-world “tough guy”has returned to reclaimhis title and is showing

no signs of slowing down.

“I think my proudest achievementis that I’ve never missed a day’s

work in my life.”

64342_B.r3 2/10/05 2:55 PM Page 30

Page 17: Perform 3

PERFORM 33

James Caan

COVER STORY

“Medicine is moving right along.” He should know—he sits onthe board of the Joan English Fund for Women’s CancerResearch, and he and his wife, Linda, strongly support its variousfund-raising activities.

When asked what advice he would offer people about enjoyinglife, it’s this: “You’ve got to stay in shape, and that’s the keything. I mean, even now, with all my shoulder surgeries and what-not, I’m still able to do what I want—it just takes a little effort.Don’t look at your birth certificate and give up. I know someguys near eighty who still go to the gym, and they can outrun meand you. It’s just a state of mind. There are so many things nowthat can keep us young and fit. There’s a lot available to peopleout there who want to continue to do whatever it is that they liketo do for a long time.”

Just being CaanThroughout it all, Caan doesn’t see himself as anything special—

just an experienced actor who has had success, thanks to hardwork and dedication. “Something I’m proudest of is that I’m stilldoing it, enjoying it, and still in demand. So that’s probably thecrowning achievement, as far as I’m concerned. And getting respectfrom the young guys that I watch and [who I] respect myself.”

“Even now, with all myshoulder surgeries and whatnot,

I’m still able to do what Iwant—it just takes a little

effort. Don’t look at your birthcertificate and give up.”

As further proof that this screen legend practices what hepreaches, Caan has managed to squeeze in an appearance in theupcoming film Dogville, in which he plays Nicole Kidman’sfather. Although he’s thrilled to still be doing the parts he wants—and only the ones he wants—Caan does occasionally miss beingthe up-and-coming Lothario: “I’m getting a little tired of theseyoung, pretty girls coming up to me and telling me how muchtheir mother loves me,” he jokes. Hey, Jimmy, take heart: at leastthey didn’t say it was their grandmother…yet!

The Joan English Fund forWomen’s Cancer Research

The Joan English Fund supports scientific research to help withearly diagnosis, prevention, and treatment of women’s cancers,including ovarian, breast, uterine, endometrial, cervical, and others.Joan English’s family created the fund after she lost her battle withlate-stage ovarian cancer in August 2000, at the age of sixty-nine.

James Caan sits on the fund’s board of directors and takes part infund-raising events with his wife, Linda. The fund is being used tosupport the purchase of state-of-the-art research equipment, whichwill be used to search for gene markers and tumor suppressorgenes. Using this equipment, researchers hope to see rapid break-throughs in detection and treatment. Most of all, they hope theirfindings will help more women win the fight against cancer.

The fund also supports the work of Dr. Ferid Murad, M.D.,Ph.D., a Nobel Prize winner and professor and chairman of theDepartment of Integrative Biology, Pharmacology, and Physiologyat the University of Texas Medical School.

To learn more about the fund,visit http://curewomenscancer.org.

32 PERFORM

James Caan

COVER STORY

Caan hits the jackpot in “Las Vegas”In his first starring role in a television series, Caan plays Big Ed

Deline, the head of an elite surveillance team that is charged withmaintaining security for the fictional Montecito Resort & Casino inLas Vegas. What are the odds that Caan can ride his latest role tothe top? Let’s just say, NBC quickly renewed this funny, sexy seriesfor next fall after it was ranked the #1 new adult drama this season.

With his history of tough roles buoying him, Caan has animposing presence, and is a natural as the chief of security who’snot afraid to mix it up when one of the casino-goers gets out ofhand. “Las Vegas” lets him show off his razor-sharp sense ofhumor, as well as his guiding force as a father: At the Montecito,he serves as father figure to the members of his young and (ofcourse) beautiful security team, including actors Nikki Cox,Vanessa Marcil, Molly Sims, Josh Duhamel, and others. As withanything James Caan does, he is fiercely committed to the future

success of the show. “It takes time. Next yearhopefully will be a lot better than this year, and Ihope it keeps growing to the point where we’re allpretty happy.”

On keeping in shapeFrom football, to a black belt in karate, to nine

years on the rodeo circuit, Caan has clearly led aphysically demanding lifestyle. How does he do it?“I’ve had eleven shoulder surgeries!” he exclaimswith a hearty laugh. “When you’re young youthink you’re indestructible, you know? I’m goingto be sixty-four, which is really hard to say becauseI still feel thirty-two.”

Despite his occasional aches and pains, Caanconfides that he has no plans for slowing down.He remains a firm believer in the power of modernmedicine as an aid to his longevity. Caan is partic-ularly enthusiastic about the future of medicine.

Breaking through barriersAfter years of being out of the mainstream, Caan realized that

to support his growing family he would have to make a return toacting. “I woke up one morning and I didn’t have any money.Absence does not make the heart grow fonder, that’s all I cansay.” But after being one of Hollywood’s golden boys for so manyyears, Caan soon learned that Hollywood is quick to forget evenits most celebrated stars: “People kind of forgot me, so it wasn’tas if I thought that I could just come right back.”

With his mind set on getting back into acting, Caan relied onwhat had gotten him to the top the first time around—hard work,followed by more hard work. After a string of progressively larger roles in the 1990s, he’s reclaimed his golden-boy status. In 2003, he starred as Will Ferrell’s workaholic father in the Christmas blockbuster film, Elf. And now he’s “the man” on “Las Vegas.”

James CaanBy the Numbers

75 feature films

9 years on the professional rodeo circuit

6 years coaching Little League, football, and soccer

4 Golden Globe nominations

1 top-rated new adult drama —“Las Vegas”

1 Academy Award nomination

1 Emmy nomination

1 black belt in karate

0 days of work missed

0 regrets

Actors James and Scott Caan (son) James Caan and cast on the set of his hit TV series “Las Vegas”

64342_B.r3 2/10/05 3:02 PM Page 32

Page 18: Perform 3

“The race is not always to the swift...but to those who keep on running.”

“Act as if it were impossible to fail.”

““WWe come to feel as we behae come to feel as we behaveve..””

“I bend but do not break.”

“Forever is composed of nows.”

–Author Unknown

–Dorothy Broude

––PPaul Paul Pearsallearsall

–Jean de La Fontaine

–Emily Dickinson

“We come to feel as we behave.”–Paul Pearsall

Proud to support individualsliving life in the moment.

B E XTR A . c omPERFORM 35

Grape Expectations

TRAVEL & LE ISURE

We stand in the crisp fall air and watch as a half dozen workers quick-ly load trays of grapes onto a forklift, feeding them into the destem-ming and crushing machine. It’s the last of Ingleside Plantation

Vineyard’s fall harvest, or as they call it around here, “the crush”. By mid-October, the crush is ending for vineyards like this one on Virginia’s

Northern Neck. Colder mountain regions may have several more weeks to go.Harvest is a tough business—watching the weather report, making sure to haveenough workers at the right time, and crushing the grapes before they go bad.

Doug Flemer, whose family has owned this farm since 1890, recalls rushing topick grapes before a hurricane hit, as well as the harvest of 1996, when it rainedevery weekend. “A lot of vines just didn’t get picked that year,” he says.

Virginia’s hard-to-predict weather makes each year’s wine a bit different, simi-lar to the wines of France. In both regions, people look forward to barrel tast-ings. In California, where the weather is more stable, wines taste nearly the same,year after year.

The grapes being crushed today were handpicked under sunny skies and putinto trays known as lugs. The lugs were stacked in a refrigerated truck overnight,to kill bacteria and make the grapes pop open in the crusher.

“All the juice from these grapes is white,” says our guide, Bruce Perrygo. If thisjuice were going to be used to produce a white wine, the grapes would go into apress that keeps the skins separate from the juice. Since this is going to be a redwine, the skins are put in with the juice and are fermented with yeast, whichturns the sugar into alcohol.

The noise of the crushing machine, the strong smell of ripe fruit, and the hun-dreds of fruit flies buzzing around don’t quite fit the romantic image of wine-making that we had in mind. But this is just the beginning. The art and scienceof winemaking start after the crush. It can be a long process—often years—of fil-tering, testing, tasting, and aging. There are many decisions to be made, and allof these choices will affect the taste of the wine.

It isn’t just for breakfast anymoreWinemaker Bill Swain takes a sip of the juice in his laboratory-like workshop,

located in the barn of his century-old farm. He measures the sugar content of thegrapes with a special meter while they are still on the vine. He also uses his owntaste test: When the grape seeds taste like Grape-Nuts® cereal—rich, sweet, andgrainy—they are ready to be picked. The winemaker’s art is the ability to predictwhat this raw grape juice will taste like after years in a bottle.

GrGrapeExpectctationsGrGrape

ExpectctationsGrape

ExpectationsVirginia Wines Come of Age

by Mary Burnham

64342_B.r3 2/10/05 2:57 PM Page 34

Page 19: Perform 3

PERFORM 37

Grape Expectations

TRAVEL & LE ISURE

36 PERFORM

Grape Expectations

TRAVEL & LE ISURE

The father of American wineVirginia has more than eighty farm wineries like Ingleside—

twice as many as ten years ago—from the Chesapeake Bay to theCumberland Gap. Ingleside is one of the older Virginia wineries,producing its first commercial wines in 1980. It already has agreat reputation in Virginia’s young wine industry, where age ismeasured in decades instead of centuries.

In international tasting competitions, Virginia labels are rank-ing up there with the big boys from France. Even CaliforniaWine Guru Robert Mondavi said that Virginia would soonbecome a world player in the wine business.

Although President Thomas Jefferson is credited as being thefather of American wine, and he chose the first vintages to bestocked at the White House, no one really knows if he lived longenough to try any of his native state’s fine products.

Jefferson began experimenting with American grapes, but hestopped when the Revolutionary War broke out. Short-term suc-cess was achieved in the mid-1800s with a mix of American andEuropean grapes. Some of these grapes—Norton, Catawba,Niagara, and Concord—are still grown today. Sadly, most of thevineyards were destroyed in the Civil War. Then, in the early1900s, Prohibition brought the whole process to an end. Wineswere not produced again in Virginia until the 1960s. In the1970s, Chardonnay, Reisling, and Cabernet Sauvignon began tobe bottled in the area. Virginia now ranks eleventh in wine pro-duction among the fifty states.

Growing placesOnly time will tell how Virginia’s young wines will fare against

the best wines of the world, but it didn’t take long for severalnew wineries to make their mark. Virginia’s biggest success storymay be the Williamsburg Winery, the largest in the state. Wewere amazed to learnthat it produces onequarter of the winesmade in Virginia—about sixty thousand toseventy thousand casesa year. That’s a lot ofwine—especially sincethe owner created hisfirst wine, Governor’sWhite, only fifteen yearsago. It is now the mostpopular of all Virginia wines. The Williamsburg Winery has beeninvited to several international tastings, where its wines werepoured alongside some from European vineyards that date backto the Renaissance.

The Kluge Estate Winery and Vineyard Farm Shop, run byPatricia Kluge, is not as large as the Williamsburg Winery. Kluge,owner of a huge estate near Charlottesville, is already a wealthywoman, but her dream is to become one of America’s premierewinemakers. When her winery opened in spring 2003, the publichad one of its first samplings of her Bordeaux-style 2001 NewWorld Red and a sweet aperitif called Cru.

Just three years old, the winery introduced its first vintage infall 2002 with 289 bottles of a limited edition 2000 New World

Red, each bottle signed by Kluge(whose profile is on all herlabels), and boxed in a case madeof American walnut, designed byLord David Linley. Kluge hasspared no expense in achievingher vision, putting together theworld’s top winemaking people.The wine is, as you’d expect,expensive. Still, we found theFarm Shop to have the friendlyfeel of a country store, with ashop for potted herbs andVirginia preserves, and a restau-rant where you can eat lunchwhile you sample the wines.

During Virginia’s Historic Garden Week, Kluge opens her gar-dens, the chapel she designed herself, and her conservatory ofexotic plants to the public.

A few miles away from Ingleside, a brand new winery, Oak Crest, opened its tasting room to the public in 2003. The stone fireplace and outdoor deck tables make a cozy settingfor tastings. Conrad and Dorothy Brandts and their two sons alljuggled full-time jobs while building their vineyard, stoppingwhenever they ran out of money. Making wine seems to be inConrad’s blood. When he was still in high school, his Germangrandfather taught him how to produce wine for their family. In 1985 he purchased fourteen acres on Virginia’s NorthernNeck. In 1986 he started planting vines and, a decade later, started building the winery.

The Brandts make small batches of Cabernet Sauvignon,Cabernet Franc, and Merlot, but their specialty is wine madefrom the white Symphony grape, which is similar to those usedin German Rhine wines. The couple doesn’t plan on getting richmaking wine. It is something they love to do in retirement, andthat they can pass on to their children. Their small, family-operated winery is a prime example that for some, winemakingis more of a passion than a business.

Wine Pronunciation KeyOrdering wine can be

difficult—many of us have

trouble wrapping our tongues

around some of those strange-

looking names. The following crib

sheet will help you at the wine

store or restaurant:

Aperitif (a-par-uh-TEEF)

Beaujolais (bow-jho-lay)

Cabernet Sauvignon (kab-er-nay saw-vee-nyon)

Chablis (sha-blee)

Chardonnay (shar-dun-nay)

Fumé Blanc (foo-may blahn)

Merlot (mer-low)

Pinot Grigio (pee-no GREE-jee-oh)

Pinot Noir (pee-no nwar)

Pouilly Fumé (poo-yee foo-may)

Reisling (REES-ling)

Rosé (ro-zay)

Sancerre (san-sair)

Sauvignon Blanc (saw-vee-nyon blahn)

Vouvray (voo-vray)

Wine 101Though there is an entire

universe of wines to explore,

the three basic categories

below will give you

a good head start.

TABLE WINES. The most commonly pur-chased wines, these are reds and whites thatare served with a meal. Whites are chilled;reds are served at room temperature. Redsare aged and whites, for the most part, are not.

SPARKLING WINES. These are the “bubbly”wines, like champagne, that are usuallyserved on special occasions. Sparkling winesare made around the world, the same way as champagne, but with different grapes.

FORTIFIED WINES. These heavier wines, suchas port and sherry, are made by adding winealcohol or brandy. They are usually servedwith desserts or as an after-dinner drink.

Post Grape-Nuts is a trademark of KF Holdings.

Mary Burnham is coauthor of Hiking America Virginia and Exploring the Small Towns of Virginia and Maryland.

Year-roundVirginia Wine Events

More than 350 Virginia wine events, from individual

barrel tastings to giant festivals, take place throughout

the year. There are polo matches, grape stompings, bluegrass

concerts, garlic and mushroom festivals, and even winemak-

ing seminars. All events are listed in the annual Virginia

Wineries Festival and Tour Guide, which also lists all eighty

of Virginia’s wineries, with maps and directions.

For a free copy of the guide, please contact the Virginia Wine

Marketing Office at (800) VAVINES (828-4637) or visit

www.virginiawines.org.

64342_B.r3 2/10/05 2:57 PM Page 36

Page 20: Perform 3

bright thinking

38 PERFORM

T IPS & TRENDS

PERFORM 39

T IPS & TRENDS

“Optimists coped by taking a negative situation and turning itinto something as positive as possible,” says Carver, who followedthese women for one year. “They said, ‘My life isn’t over; it’s justgoing to be different.’ The pessimistic women were more likely todeny the disease and essentially give up.”

Learn opt imismThe good news for doom-and-gloomers is that they can train

themselves to have a more positive outlook. In his book, LearnedOptimism (Pocket Books), Seligman says you should start by mind-ing your ABCs — that is, keep a record of your Adversity, Beliefs,and Consequences.

Adversity, according to Seligman, can be almost anything — aleaky faucet, a baby who doesn’t stop crying, or being ignored by aspouse. Seligman says the next time a negative event occurs in yourlife, write down your thoughts about what has happened withoutgoing into your feelings. Your beliefs are how you interpret theadversity or bad event. For example, “I just blew my diet” and “I am incompetent” are beliefs. “I feel sad” is a feeling.

Next, write down your feelings and what you did afterward. Didyou feel sad, anxious, guilty? Write down as many feelings andactions as you can. “I ate a carton of ice cream” is a consequence.

By completing this exercise, Seligman says, you’ll find that yournegative beliefs are probably exaggerated. Once you recognize this,challenge those beliefs whenever they occur. “Don’t let your nega-tive beliefs run your emotional life,” Seligman cautions. “Once youget into the habit of questioning your negative beliefs, your daily lifewill be much better and you will feel much happier.”

Hold that thoughtIn order to change the way pessimists think, Emmett Miller,

M.D., author of Deep Healing (Hay House), uses a technique called “selective awareness”, in which people try to train themselvesto think positively.

“I tell my patients to focus on a success in their life,” says Miller.“It can be the birth of a child, or a vacation when you’ve had oneof those perfect moments. You have the power to direct your mindto think about whatever you want. Focusing on a place where youfelt good about yourself will give you more optimism.”

Optimistshave better l i festy lehabits , and recover

f rom i l lnessesfaster than

pessimists do.

brightbrightOptimists are healthier

as well as happierby Samantha Jacqueline

it has started to rain quite hard, and you have forgotten to bringyour umbrella. You think:

(a) It always rains when I don’t have my umbrella with me. (b) I’m going to get soaking wet and be miserable all day. (c) This rain is going to be great for the lawn and garden.

If you chose (c), you are probably an optimist, and psychologistssay that optimists are not only healthier than those who have a neg-ative outlook, they might live longer as well. Evidence also suggeststhat optimists catch fewer infectious diseases, have better lifestylehabits, and may recover from illness faster than pessimists do.

There are a number of ways to measure optimism and pessimism,and the old saying about seeing the cup half full or half empty isonly part of it. According to one expert, it all comes down to theway we explain the events in our lives.

Martin Seligman, Ph.D., professor of psychology at theUniversity of Pennsylvania in Philadelphia, says pessimists believetheir lives are an endless string of pitfalls for which they have onlythemselves to blame. Optimists, on the other hand, do not blame

themselves for their misfortune, which theybelieve is only temporary. In fact,

unlike pessimists, who tend togive up easily, optimists

are inspired to tryeven harder.

Cope with stressAlthough a sunny disposition will not protect you against illness,

research has shown that optimists have fewer physical problems. In a study published in the Journal of Personality and SocialPsychology, ninety law students at the University of Kentucky inLexington were followed from the beginning through the middle oftheir first semester. The students, who were all healthy at the time,were asked to fill out questionnaires to find out what their expecta-

tions were for their lives in general, as well as their expectations for success in law school. The study revealed that the most optimistic students had the strongest immune systems, which protect against illness.

“Optimists cope better with stress, experience fewer negativemoods, and have a healthier lifestyle, all of which could helpstrengthen the immune system,” says Suzanne Segerstrom, Ph.D.,lead author of the study.

Let happy thoughts heal In study after study, researchers have found that lookingon the bright side contributes significantly to a person’s

recovery. For example, when coronary bypass patientswere tested for their level of optimism before and after

surgery, those who were the most optimistic returnedto their normal activities at a faster rate than

pessimists did.

“The optimists got out of bed sooner, reporteda higher quality of life, and were less likely to suffer a heart attack during the surgery,”says Michael Scheier, Ph.D., of CarnegieMellon University in Pittsburgh, whotracked the patients’ responses to surgeryfor six months.

Likewise, accepting one’s fate, ratherthan denying the problem, is another keyfactor in the recovery process, accordingto Charles Carver, Ph.D., professor ofpsychology at the University of Miami inCoral Gables, Florida. Carver tested theemotional well-being of fifty womenwho were diagnosed with breast cancer.

Jo in the opt imistsHard-core naysayers might want to consider therapy, but

psychologists say it is extremely helpful to have a positive-thinkingfriend or partner with whom you can talk honestly and get feedbackand support. It is also important to avoid negative thinkers.

“Seek out the people that you want to be like,” advisesPsychologist Christopher Peterson, Ph.D., of the University ofMichigan in Ann Arbor. “It’s rough to be the only optimist in a fam-ily or group of pessimists.”

Avoid pess imismTo a true pessimist, becoming a Pollyanna may sound as unlikely

as changing into a butterfly, but there is still hope. A recent study of224 people middle-aged and older found that avoiding pessimismmay be important for lowering stress and improving one’s health.

“Previously, optimists and pessimists were considered direct opposites,” says Research Psychologist Susan Robinson-Whelan,Ph.D., lead author of the study, conducted at State University ofOhio in Columbus. “We did not find this to be the case. It might beeasier for people who tend to be pessimistic to say, ‘I don’t have tolearn to be an optimist in order to be physically healthy, but I shouldtone down my negative thinking.’”

Psychologists say thatopt imists catch fewer

infect ious d iseases and may l ive longer than those who have a negat ive out look.

thinkingthinking

64342_B.r3 2/10/05 3:04 PM Page 38

Page 21: Perform 3

40 PERFORM

T IPS & TRENDS

Grilled Steak au PoivrePrep: 10 minutes Cook: 6 to 10 minutes Serves: 4

4 shell or rib-eye steaks, cut 3⁄4-inch thick, boned and trimmed

11⁄2 teaspoons olive oil1 teaspoon salt3-4 tablespoons coarsely cracked peppercorns

1. Prepare hot fire. Rub steaks lightly withoil and season with salt. Spread crushed pepper on waxed paper and press both sidesof each steak into peppercorns to coat.

2. Cook steaks on an oiled grill set 4 to 6inches from coals, turning once or twice,until nicely browned outside yet still pinkand juicy inside, about 6 to 8 minutes forrare, 8 to 10 for medium rare. If you likeyour meat cooked more thoroughly, use thehandy tips given below.

Nothing rivals the aroma of a sizzling steakhot off the grill. The secret of this dish is in itssimplicity. Most meat is best cooked quicklyover a hot fire. If you don’t have a meat ther-mometer, touch the meat, using the followingas a guide: If it feels very soft and doesn’tspring back, it’s still raw. Rare meat springsback but feels somewhat soft in the center;well-done meat should feel completely firm.

Maple Barbecued ChickenPrep: 10 minutes Marinate: 2 hours Cook: 35 to 45 minutes Serves: 4

1 cup tomato sauce1⁄4 cup cider vinegar1⁄4 cup vegetable oil2 tablespoons honey or maple syrup2 teaspoons chili powder1⁄2 teaspoon saltDash of cayenne1 3-pound chicken, cut up

1. In a small stainless steel or nonsticksaucepan, combine tomato sauce, vinegar, oil,honey, chili powder, salt, and cayenne. Bringto a boil over medium heat. Reduce heat tomedium-low and simmer, stirring occasionally,until sauce is slightly thickened, about 10 min-utes. Set aside and cool to room temperature.

2. Rinse chicken with cold water and pat dry.Arrange pieces in a glass baking dish andpour sauce over chicken; turn pieces to coat.Cover with plastic wrap and marinate 2 to 3

hours in the refrigerator. Set aside some sauceto brush on the chicken while it is on the grill.

3. Prepare a hot fire. Remove chicken frommarinade and place skin side down on anoiled grill set about 6 inches from coals;reserve marinade. Grill until skin is brownedon bottom, 10 to 15 minutes. Turn piecesover and grill for 10 to 15 minutes, checkingoccasionally for flare-ups. Brush with barbe-cue sauce and continue to grill, turning andbasting frequently with sauce, until chickenis cooked through with no trace of pink nearthe bone, about 15 minutes longer.

Chicken is a low-fat, tasty alternative tobeef and pork. PERFORM™ recommendsmarinating first. A variety of marinades adddistinct smoky flavors. You can preparechicken three times a week and have com-pletely different results every time. Turkey,duck, and game hen can be substituted forchicken in many recipes.

Skewered Marinated Vegetables Italiano Prep: 10 minutes Marinate: 1 hour Cook: 10 minutes Serves: 4

1 medium yellow summer squash, cut into 3⁄4-inch pieces

1 medium zucchini, cut into 3⁄4-inch pieces8 cherry tomatoes8 medium mushrooms3⁄4 cup bottled Italian salad dressing

1. In a large bowl, combine squash, zucchini,tomatoes, and mushrooms with salad dress-ing. Toss to coat well. Cover with plasticwrap and marinate 1 to 4 hours at roomtemperature, or overnight in the refrigerator.

2. Prepare a hot fire. Thread vegetables sep-arately onto 4 long metal skewers, so thateach skewer is filled with the same vegetable.Place on an oiled grill set 4 to 6 inches fromcoals. Grill, turning frequently and brushingwith reserved marinade, until each vegetableis cooked, 2 to 3 minutes for the tomatoes, 8 to 10 minutes for the squash and zucchini,and 10 minutes for the mushrooms.

3. To serve, slide vegetables off skewers andtoss in a serving bowl, or arrange decora-tively on a platter.

Almost any vegetable can be grilled suc-cessfully. The smoky fragrance and crustyexterior accentuate the natural flavor ofeverything, from artichokes to zucchini.

Small vegetables caneasily be cooked on askewer. Even kids whonormally go straight to the hot dogs willreach out for a vegetable kabob. Herbs andspices can be added to almost any vegetablefor variety.

Grilled Tuna Steak with Lemon-Caper ButterPrep: 10 minutes Cook: 10 to 12 minutes Serves: 6

8 tablespoons (1 stick) unsalted butter, softened

3 tablespoons fresh lemon juice1⁄2 teaspoon grated lemon zest2 teaspoons Dijon mustard2 teaspoons capers, drained6 8-ounce tuna steaks, cut 3⁄4-inch thick1⁄4 cup vegetable oil

1. Mix together butter, 2 tablespoons lemonjuice, lemon zest, mustard, and capers. Setlemon-caper butter aside.

2. Prepare a hot fire. Brush tuna steaks withoil. Drizzle remaining 1 tablespoon lemonjuice over fish. Place steaks on an oiled grillset 4 to 6 inches from the coals. Grill, turn-ing once, until firm and opaque at the center,about 10 to 12 minutes.

3. Remove from heat and top each steakwith 1 tablespoon lemon-caper butter.

Whether your fish comes out of the ocean,a freshwater stream, or the local market, ahot grill is a great way to enjoy seafood.When choosing fish, keep in mind that filletswith skin on are much easier to cook on thegrill than skinless fillets. Set fish skin sidedown first, then turn carefully with a widemetal spatula. Because of its delicacy andtendency to break apart, it should only beturned once.

The test for doneness for all fish, shrimp,and scallops is that they should be opaquethrough to the center, but still moist and tender. As with meat, fish will continuecooking for a minute or two after it isremoved from the fire, so be sure to take itoff the grill as soon as you think it is done.You can always put it back for a little longer,but if it’s overcooked, there’s no going back.

Cooking over an open fire dates back to the cave dwellers, and there are plenty of good reasons why it remains a favorite today. It is a wonderful way to prepare healthful foods such as fish, chicken, and vegetables. Whether you’re using a disposable hibachi or a top-of-the-line grill, barbecuing is a perfect way to enjoy spring and summer.

To make sure that every dish is great, try these simple but delicious recipes from 365 Great Barbecue & Grilling Recipes.You will find that they require few ingredients and can be prepared in minutes. Aside from giving you a chance to relax and enjoy the outdoors, these dishes will make you the king or queen of the grill.

Adapted from the book 365 Great Barbecue &Grilling Recipes, by Lonnie Gandara. Published byarrangement with HarperCollins Publishers. All rights reserved.

PERFORM 41

One of our favorite things aboutgrilling is that just about

anybody can do it, regardless of cooking skills or experience.

It is a great way to entertainfriends, and a great gathering

place when you are hosting a large party or family reunion. To top it off, there’s not much to clean up when you’re done.

Here are some tips before you fire up:• Aromatic wood chips such as mesquite, hickory, maple, or oak add a unique smoked flavor. Soak them in

water for about thirty seconds before placing them over lighted charcoal.

• Always heat the grill rack and brush it with oil before placing food on it to reduce sticking, and to get those distinctive grill marks you see at restaurants.

• To light the charcoal, use a tasteless vegetable oil in place of lighter fluid to avoid chemical fumes.

64342_B.r3 2/10/05 3:04 PM Page 40

Page 22: Perform 3

PERFORM 4342 PERFORM

• Lower back pain

• Menstrual cramps

Vane’s work was a big step forward, but it wasonly the beginning. In the 1980s, Dr. PhilipNeedleman found that there were 2 COX enzymes.

Discovering the roles of COX enzymes was abreakthrough in pain management

While working for the Monsanto Corporation, Dr.Needleman went to Sir John Vane’s lab in Englandto study Vane’s methods.

Needleman and his team were soon sure that therewere 2 types of COX enzymes (COX-1 and COX-2)that made prostaglandins. Soon, others agreed withhis finding. Over the next few years, the actions ofthese 2 enzymes were made known. This was a hugeleap in how man could control pain.

This finding made it clear why up to 25% ofpatients who took NSAIDs had side effects. TheNSAIDs would halt the body from making bothCOX-1 and COX-2. Up to 5% of patients had seri-ous issues with their health whiletaking them.

Finding a more selectivedrug was next

Dr. Needleman set out tomake a drug that would bemore selective in treating pain.This drug would block thebody from making COX-2, butnot COX-1, so it would be easieron the stomach. He found successin seeing his vision through.Monsanto was devoted to mak-ing this drug come to life.1

“I mobilized all the medicinalchemists at Monsanto. It was a once-in-a-lifetime chance,”said Needleman in an inter-view conducted in 1998.1

Needleman studied all theNSAIDs. He looked for theones that were effective againstpain but didn’t hurt the stom-ach. He felt these drugs wouldbe more selective for COX-2.1

Needleman’s team of researchers included Dr. JohnTalley. Talley’s job was to isolate molecules thatcould target COX-2. In 1992, Talley’s team foundsome that stopped COX-2. It was a major advance.But there was still much to be done to turn thisfinding into a pill.2

After looking at over 5000 molecules, the firstselective COX-2 was made. In 1995, the first clini-

Have you talked to your doctor about yourjoint pain lately?

Jeff Palmer did. He is an active 53-year-old jogger.On most days he runs 3 miles. It keeps him fit and hefeels better when he’s done.

Jeff wasn’t always able to do this. In 1997, hebegan to have pain flare-ups in his knees. He thoughtthat the pain would go away on its own. He waswrong. He began taking over-the-counter pain reliev-ers called nonsteroidal anti-inflammatory drugs(NSAIDs). These included Motrin®, aspirin, and var-ious other drugs available at the time. Some of themyou could only get from your doctor. They helpedhim cope with the pain.

There are new ways to treat arthritisjoint pain

In time, Jeff’s joint pain grew worse. Finally, the painin his knees was too much to bear. He began to takehis pain reliever every day. He slowly cut down on jogging to rest his knees. Even that didn’t fully relievehis pain.

A year later, in 1998, he met with his doctor. Jeff wassurprised when his doctor told him the pain in hisknees was osteoarthritis (ahs-tee-oh-arth-RYE-tis), or OA.

His doctor told him that about 40 million Americans ofall ages had it (and today it’s actually 70 million). LikeJeff, many of them were caught in a vicious cycle of pain.

Jeff was also having stomach problems. He asked hisdoctor if it could be from the NSAIDs. These drugswere known for treating pain. They were also knownfor causing stomach irritation, and in some cases,stomach ulcers.

Luckily for Jeff, the pain revolution had just begun. TheFood and Drug Administration (FDA) had just approvedthe first COX-2–selective inhibitor (COX-2). As a resultof this revolution, doctors today have a variety of effective options to relieve pain. So you—and Jeff—cankeep running.

The ancient Egyptians started us on the right track

OA is the most common joint disease. It is from wearand tear on the joints and can affect the:

• Knees and ankles• Back and neck• Hips• Hands and fingers

Many people with OA have only mild pain. Overtime the cartilage wears down, causing more andmore pain and swelling. Rheumatoid arthritis (roo-mah-toid arth-RYE-tis), or RA, is also a form ofarthritis. It too causes swelling and pain. RA, howev-er, can affect the whole body. It is a disease in whichthe body’s own immune system attacks the joint, dam-aging it and the way it moves.

Man has been trying to get rid of arthritis pain forthousands of years. Most tried to beat pain in the sameway, it turns out. Ancient Egyptians used myrtle leaves.Hippocrates drew the sap of willow bark. The activedrug in both was salicylic (sal-uh-SILL-ic) acid. In 1897,a more effective drug—acetylsalicylic (uh-SEE-til-sal-uh-SILL-ic) acid, better known as aspirin—was made.

Discovering how aspirin works was the keyto modern pain relief

In 1971, Sir John Vane of Britain found out howaspirin took away pain. It blocked the body from mak-ing a type of chemical called an enzyme. The enzymewas cyclooxygenase (COX). And it in turn helps makeprostaglandins (prahs-tuh-GLAN-dinz)—chemicals thattrigger swelling. These are made only when the body ishurt. This was a great finding that would lead to betterways to treat pain. Vane won a Nobel Prize for his work.

By this time, these pain relievers had become widelyprescribed for:

• OA and RA

• Acute pain episodes (from events such assprains, strains, or surgery)

Emerging from theShadows of Pain

Shedding Light on the Evolution of Arthritis and Pain MedicationThe development of COX-2 drugs has greatly improved

the treatment of arthritis and pain

cal trials were started. In 1998, it was approved bythe FDA for the treatment of arthritis. This drug isnow sold by Pfizer.

Millions of people have used COX-2s since 1998

Since then, a number of COX-2s have been put on the market. More than 56 million people around the world have asked their doctor for, or used, aCOX-2 for arthritis pain. As a result, 2 out of every5 prescriptions for a pain reliever in the UnitedStates are for COX-2 drugs.

COX-2s have been highly effective in relievingarthritis pain. The latest of these drugs to beapproved by the FDA was BEXTRA® (valdecoxibtablets). It has quickly earned a place as a strong drugthat works and is gentle on the stomach. Doctorswant their patients to stay active, with whateveractivity that is right for them. BEXTRA may be agreat choice for those who want to do things theyenjoy doing. The success of BEXTRA is evident.Since it became available in 2002, more than 5 mil-lion people have tried it—in the United States alone.

COX-2s are effective and cause few side effects

Like Jeff Palmer, you want to be active when youfeel like it. You’re tired of the pain in your knees orhands holding you back. Talk with your doctor. Heor she has more options to fit your needs today thanever before. The COX-2 drugs are effective andcause fewer side effects than other pain relievers.

A COX-2 inhibitor targets the action of COX-2…while allowing COX-1 to protect the stomach lining

COX-2 allows chemicals to be produced that cause the pain and inflammation of arthritis.

=pain =no pain =protected=not protected

Elbow Joint Stomach

COX 2

COX 2

COX 2

COX 2

COX 2

COX 2

COX 2

COX 2

COX 1

COX 1

COX 1

COX 1

COX 1

COX 1

COX 1

COX 1

COX 1

COX 1

64342_B.r3 2/10/05 3:06 PM Page 42

Page 23: Perform 3

44 PERFORM

American Pain Society prefers COX-2–selective inhibitors for the treatment of OA/RA pain and inflammation

Important information about COX-2–selective inhibitors

BEXTRA is not for everyone. PrescriptionBEXTRA should not be taken if you’vehad allergic reactions to certain drugscalled sulfonamides, aspirin or otherarthritis medicines or if you’ve hadaspirin-sensitive asthma or are in latepregnancy. It is not recommended if youhave advanced kidney disease. Tell yourdoctor if you have kidney or liverproblems. In rare cases, serious stomachproblems such as bleeding can occurwithout warning. Tell your doctor rightaway if you develop blisters in the mouthor a rash, as it can be a sign of a seriousskin reaction that may be life threatening.If you experience other unusual symptomswhile taking BEXTRA, tell your doctorimmediately. The most common sideeffects are headache, abdominal pain,indigestion, upper respiratory infection,nausea and diarrhea.

Dr. Mona Wahba was on the medical team thatbrought COX-2s to the public. Being able to helpmillions of people is a dream she has had since theage of 4. “I am so proud to be working on medicinesthat are making an impact in the lives of peoplearound the globe,” says Dr. Wahba.

What isyouropinionofhowpainwastreatedbeforeCOX-2s?There have always been options for patients with joint pain. Theproblem was, those that worked the best often hurt the stomach.

What was it like working on the COX-2s?Oh, it was such a thrilling time for the entire industry. We knew thatwe had something that could be a true breakthrough in treating pain.

Where does treating pain go from here?The goal is always to offer the most pain relief with the fewest sideeffects. The COX-2s are a nice step in the right direction.

References1. Groopman J. Super aspirin: new arthritis drug—Celebra. The New Yorker. June 15, 1998:32-37. 2. Krasner J. Slugger on deck: start-up signs a champ in the world of drug discovery. The Boston Globe. April 3, 2002. In the News Web site.

Available at: http://www.microbia.com/news/A04_03_02.html. Accessed February 24, 2004. 3. Simon L, Lipman A, Jacox A, et al. Guideline for the Management of Pain in Osteoarthritis, Rheumatoid Arthritis, and Juvenile Chronic

Arthritis. 2nd ed. APS Clinical Practice Guidelines Series, No. 2. Glenview, Ill: American Pain Society; 2002:44-55.

Motrin (ibuprofen) is a registered trademark of McNeil Consumer Products Company.

PERFORM 45

Finance

FAMILY & L IV ING

Your Monthly

MONEY CALENDARby Nolan Wainsworth

Whether you’re looking to invest, cut taxes, save money, or retire early, PERFORM’s financial navigatorcan help you reach your goal. In this issue, the Monthly Money Calendar offers smart, no-nonsense

tips and strategies for getting the most out of what you have. This to-do list acts as both a moneymanagement guide and a friendly reminder that can have a big payoff at the end of the year.

Manage your 401(k).If you haven’t already doneso, alter your contributionso that you max out yourcompany’s match. Mostcompanies contribute fifty

cents for every dollar that you put in, up toa certain level—usually 6 percent. That’s animmediate 50 percent return on your money.The maximum 401(k) contribution for 2004is $13,000 per person ($16,000 if you’reover fifty). If your company doesn’t matchyour contributions, try to set aside that extraamount yourself in a savings account.

JUNE✔ Monitor your ATM

withdrawals and cashpurchases. Decide howmuch cash you willtake out each weekand make it last. Try

to decrease your withdrawals over time.If you have money left over at the endof the month, invest it or put it into asavings account. People who keep trackspend far less and save more. Youmight want to keep a little notebookwith you to record your cash purchases.

JULY✔

Pay off your carloan and tune up yourcar. Interest on yourcar is not deductibleunless it’s through a home-equity loan.

Even then, the rate is probably higherthan that of your mortgage. Pay it offand save. And while you’re at it, avoidcostly car repairs by having the oil andfilter changed every 3,000 to 5,000miles, and radiator fluid every twoyears. Also, have your local service sta-tion check the engine belts for cracksor tears and change the transmissionfluid if it has turned murky brown.

AUGUST✔

Open an IRA. Whilemost money expertsagree that IRAs are a smart investment,you should decide ifyou are better off

paying taxes up front, or if you willbenefit more from a traditional tax-deferred plan. If you expect to be in a lower tax bracket at the time youwithdraw, the traditional tax-deferredIRA is probably your best bet. Eitherway, many consultants suggest thatyou max out your company’s retire-ment plan first.

SEPTEMBER✔

Update your home-owner‘s insurance.Make sure your cover-age hasn’t changedsince you originallytook out the policy.

Changes can cost you a lot, so stayingup-to-date is crucial.

OCTOBER✔

Make a documentlist. Keep yourdeductible expensesand property taxreceipts, mortgageinterest records,

canceled checks, and checkbook registers in well-marked folders. This is a great time-saver at tax time.

JANUARY✔ Use up the money in

your flexible spendingaccount and plan nextyear’s deduction. Flexiblespending accounts (pretax money deducted

from your salary for health-care expenses)are great unless you have a balance at the end of the year. The use-it-or-lose-itpolicy makes it important to estimatenext year’s contribution accurately. In the meantime, ask a plan representativeor someone in your human resourcesdepartment for spending suggestions if you’re in danger of having money left over at the end of this year.

DECEMBER✔

Make your homemore energy efficient.Check the weather-stripping around yourdoors and windows,clean heat ducts,

change the furnace filter, and tune up your oil or gas unit. A typicalhousehold can save up to 50 percentoff utility bills this way. You might alsowant to consider having a professionalhome inspection that includes the roof,drainage system, crawl space, andfoundation. It may cost around $400,but it can save you thousands of dollars in repairs down the road.

NOVEMBER✔

Start saving.Setting aside 10 per-cent of your income is optimal, but if youcan’t do that rightnow, try to set aside

a smaller amount, even if it is just $25a week. Write a check for whateveramount you choose every Friday, orhave your bank automatically debityour checking or savings account, andput the money into a mutual fund.Look for funds with below-average risk,low minimum purchase requirements,and a record of steady, solid returns.

MAY✔

Start paying a littleextra on your mortgage.You don’t have to com-mit to paying a specificamount. Simply roundup your monthly pay-

ment to the nearest hundred. If you prepay $100 a month on a $150,000loan, you will save $72,952 in interestand shave seven and a half years off theloan. Also, if current mortgage rates areat least two percentage points lower thanthe rate you have now, you might wantto think about refinancing, but ask yourbank if it is offering rate modificationsbefore you do. To keep your business,some banks will lower your rate, usuallyfor a small fee, without changing theother terms of your mortgage.

APRIL✔

Photograph yourpossessions. Spring is a great time to takepictures of your valu-ables, such as jewelryand furniture, and

any other assets in your home. Keepthe photos in a safe deposit box sothey aren’t destroyed in the event of a fire. This will be a great help if youever need to file a claim for damage or theft.

MARCH✔

Lower your creditcard debt. Check yourcredit cards to see ifthe annual percentagerate (APR) you’re paying is above

average for a comparable card listed on www.bankrate.com. If the APR is higher, call your issuer and ask for arate adjustment. Often the companywill lower your rate rather than loseyour business. You can save hundredsof dollars this way. If you have a$7,000 balance, cutting your rate from 16 percent to 10 percent would save you $420 a year.

FEBRUARY✔

Our articles, columns, and other features should not be construed as investment advice,nor does their appearance imply an endorsement by PERFORM™ of any specific securityor trading strategy. An investor's best action must be based on individual circumstances.

Osteoarthritis • With moderate-to-severe pain and/or inflammation: COX-2–selective NSAIDs recommended first-line

Rheumatoid arthritis • Concomitant with DMARDs, COX-2–selective NSAIDs recommended prior to nonselective NSAIDs

when NSAID treatment is indicated

Expert Opinion

64342_B.r3 2/10/05 3:09 PM Page 44

Page 24: Perform 3

PERFORM 47

Festivals are truly the perfect getaway for those of us wholike to relax, have fun, and enjoy activities all on our owntimetable. PERFORM™ shows you how to plan a vacation

around some of the best festivals in the country.

Proud to support individualsliving life in the moment.

B E XTR A . c om

“The race is not always to the swift...but to those who keep on running.”

““Act as if it werAct as if it were impossible to fail.e impossible to fail.””

“We come to feel as we behave.”

“I bend but do not break.”

“Forever is composed of nows.”

–Author Unknown

––Dorothy BroudeDorothy Broude

–Paul Pearsall

–Jean de La Fontaine

–Emily Dickinson

“Act as if it were impossible to fail.” –Dorothy Broude

64342_B.r3 2/10/05 3:10 PM Page 46

Page 25: Perform 3

Whether you are the kind of person who likes to go atyour own pace, or fill your time with structured activ-ities, festival vacations have something to offer. Since

most festivals take place in interesting areas, you can organize as much of your day as you want around the events of the festival, and spend the rest of your time exploring and enjoyingthe surrounding area.

PERFORM decided to send me to some of the best (but notnecessarily biggest) festivals in the country, and show you howto create an enjoyable getaway around them.

Sturgis Motorcycle Rally (August)When I went to this festival last year, it was the first time I had

been to South Dakota. But every year in August (this year it willrun from August 9 to 15), nearly half a million motorcycle rid-ers converge here for the rally.

I have only ridden a mountain bike, so I was a little intimidat-ed at the thought of going to the rally. But as soon as I got there,I was struck by the friendliness of all those who attended. Ilooked past the studded biker jackets and huge Hogs, to marvelat just how passionate these folks are about motorcycle rid-ing…even the mayor of Sturgis rides.

If you are a riding enthusiast, Sturgis offers tour rides aroundthe beautiful Black Hills area of South Dakota. For those whoare coming to be part of the 2004 celebration, the rally will offermusical acts such as ZZ Top, the Beach Boys, REO Speedwagon,and Heart. In addition, vendors offer up everything from tattoosto alligator meat. You can also check out the Motorcycle ExpoExhibit—a great show, whether you ride or not.

Accommodations are plentiful, ranging from campgrounds(Rolling Thunder Campground, 12913 Bear Butte Lake Road,Sturgis; 605-347-2118), to hotels (Budget Host Jackpot Inn,Highway 385 South, Deadwood; 605-578-7791),even to historic mansions (Homestake Mansion,108 Fairview Avenue, Lead; 605-722-6176).

So remember, you don’t need to be an expert,and tattoos are optional. Just expect to have agreat time with half a million of your closestmotorcycle buddies.

PERFORM 49

Festival Getaways

TRAVEL & LE ISURE

Terlingua International ChiliChampionship (November)

If you love to eat, a food festival getaway may be just the thing.There are festivals for everyone—from chocoholics to garliclovers. But there is probably no food that creates as much of astir as chili. Planning a vacation around it is an unusual concept,but once you’ve tasted the delights of the Terlingua InternationalChili Championship, you may become hooked on the idea andstart pioneering a secret recipe back at your ranch.

This four-day event takes place each year in Terlingua, Texas—in the heart of Big Bend Country—starting on the first Saturdayin November. Technically, the championship is the culmination ofa year’s worth of chili cook-offs, sponsored by the ChiliAppreciation Society International (CASI). Though “international”

might be a stretch, contestants from all across the country com-pete in regional chili cook-offs, earn points, and then get invitedto this chili bonanza held at the Rancho CASI de los Chisos.

Festival events for the public begin on the Wednesday beforethe start of the competition. For only $20, you can enjoy therugged terrain and unusual vendors at the ranch—and, of course,copious amounts of chili. There are also nightly musical attrac-tions and all the amenities of nearby Big Bend National Park forbeautiful countryside, raft trips, jeep tours, and horseback rides.

Sundance Film Festival (late January or early February)

I am a movie enthusiast, so when PERFORM suggested that I go to the Sundance Film Festival a few months ago, I wasintrigued. Visit the place where independent films make theirmark and be a part of the festival that has launched so manyaspiring actors and directors into superstardom? See new films before they’re released to the general public? Absolutely! So I headed to Park City, Utah.

The trip, which centered on watching new and independentfilms, was fantastic. And it wasn’t just the film viewing that madethe vacation. The atmosphere, the enthusiasm of the festivalgoers,the quaintness of the town, area activities such as sleigh rides, and the attractions of nearby Salt Lake City all contributed to a

wonderful vacation.Though Park City is a ski resort

town, people with wallets of all shapes andsizes can enjoy the Sundance FilmFestival. There are hundreds of filmsshown at the ten-day festival (heldannually in late January/early February).

You can purchase film passes that fit your budget and level of enthusi-asm. Full-access Sundance passes for2004 were $2,500, but smaller ticket

packages were available for a few hundred dollars, and individualscreening tickets were $10. Prices have not yet been set for the 2005 festival. I opted for one of the smaller ticket pack-ages, which can get you in to as many as seventeen feature filmsor documentaries.

There are two great things about these ticket packages. First, I could select the movies I was interested in seeing. And since thesefilms have multiple showings, I had the flexibility to do otherthings throughout the day.

Preservation Society of Charleston’sCandlelight Tours of Homes andGardens (September and October)

Every year, from late September through most of October, thehistoric city of Charleston, South Carolina, opens up its homesfor the Preservation Society’s candlelight tours of homes and gardens. These tours are a great vacation option that appeals tothose who appreciate history, architecture, and interior design.Since many of these homes date back centuries, homeowners areliterally opening their doors to the past.

What surprised me most was that many of these homes are notmuseums. People still live in these excellent examples of eigh-teenth- and nineteenth-century architecture, and generouslyallow the public to come in and view them. There are a varietyof tours, which highlight different historic districts of the city.They each feature eight to ten sites and are self-paced and self-guided, with volunteers stationed in the home or garden toanswer questions.

I took three tours. The Broad Street tour featured homes ofGreek Revival and Victorian design built during the Civil War.

The East Battery/Lower Tradd Street tour featured panoramicviews of Charleston Harbor. And the King Street (named afterKing George I of England) tour included some of the oldesthomes in the country.

If you are looking for a slightly quieter pace than the SturgisRally, Charleston may be the place for you.

48 PERFORM

Once you’ve tasted the delights of theTerlingua International Chili Championship,you may start pioneering a secret recipeback at your ranch

64342_B.r3 2/10/05 3:11 PM Page 48

Page 26: Perform 3

Festival Getaways

TRAVEL & LE ISURE

What are those other things in and around Park City? You cantake a stroll along quaint Main Street and check out the widevariety of shops. If you are especially lucky, you might have acelebrity sighting. Though I had no such luck, I did experiencesome great restaurants, ranging from French (Chenez, 710Lower Main Street; 435-940-1909), to Asian (Bangkok Thai onMain, 605 Main Street; 435-649-THAI), to American (350Main Brasserie, 350 Main Street; 435-649-3140).

If you are adventurous, you can enjoy Park City’s other famousoffering, the skiing. They say that the powder here is the best inthe country. But there are plenty of activities available for non-skiers, too, including snowmobiling and sleigh rides, plus somefantastic day spas where you can pamper yourself.

Though Sundance gets bigger and biggereach year, it still offers a nice mix of small-town charm and Hollywood glamour. So evenif it’s on-screen only, how many people get tosee a celebrity on their vacation?

New Orleans Jazz andHeritage Festival (lateApril/early May)

It may be the second biggest party in NewOrleans, but the New Orleans Jazz andHeritage Festival could be the best event in thisgreat city. Held in late April/early May, it’s notas crowded or physically demanding as chasingfloats at Mardi Gras, but can be just as exciting.

Attending this spectacular cultural event wasdefinitely a thrill. It has an easygoing atmos-phere and offers an escape into a world of richmusic. The 2004 festival offered the opportu-nity to see timeless artists such as Ray Charles,the Neville Brothers, Bonnie Raitt, B.B. King,Harry Connick, Jr., and Smokey Robinson per-form, as well as an eclectic group of otherartists, from zydeco bands and gospel choirsall the way to a high school jazz ensemble.

Most of the musical events are held at theFair Grounds Race Course, located ten minutes from the FrenchQuarter. Thousands of people show up for those shows, andthere are many other festival events held at venues throughout theFrench Quarter. This gives you the chance to check out all the funparts of this great city. It is easy to get around in New Orleans,with its network of taxis, buses, and the beloved streetcars downSt. Charles Avenue.

You can catch performers at Irma Thomas’s Lions Den (2655Gravier Street; 504-822-4693) or the House of Blues (225Decatur Street; 504-529-2624). As always, Bourbon Street pro-vides many more places to see musical acts, as well as enjoy someof the best Cajun food New Orleans has to offer—if your tonguecan handle it!

Next year will be the thirty-sixth anniversary of this wonderfulevent. Accommodations are frequently booked up months inadvance, so it pays to plan ahead. To soak up as much atmos-phere as possible at this festival, stay in the French Quarter andtry some crawfish, while you relax and enjoy fantastic music.

BEXTRA IS GENERALLY WELL TOLERATED.

The most common side effects in clinical trials wereheadache, abdominal pain, indigestion, upper respiratoryinfection, nausea and diarrhea. In clinical studies, the percentage of patients treated with 10-mg BEXTRA who discontinued therapy was similar to that of patients taking placebo (7.5 vs. 6.0 for placebo).

IS BEXTRA RIGHT FOR YOU?

Important Information. BEXTRA is not for everyone.Prescription BEXTRA should not be taken if you’ve hadallergic reactions to certain drugs called sulfonamides,aspirin or other arthritis medicines or if you’ve hadaspirin-sensitive asthma or are in late pregnancy. It isnot recommended if you have advanced kidney disease.Tell your doctor if you have kidney or liver problems. Inrare cases, serious stomach problems such as bleedingcan occur without warning. Tell your doctor right awayif you develop blisters in the mouth or a rash, as it canbe a sign of a serious skin reaction that may be lifethreatening. If you experience other unusual symptomswhile taking BEXTRA, tell your doctor immediately.

Knowledge is POWER

BEXTRA PROVIDES POWERFULARTHRITIS JOINT PAIN RELIEF.

Once-daily BEXTRA hits joint pain hard.• 24-hour relief. It’s what many people with joint

pain seek.• Tough on joint pain, swelling and stiffness.• Powerful and convenient. One dose takes on both

osteoarthritis and adult rheumatoid arthritis pain.

Studies show that one BEXTRA (10 mg) once a dayrelieves joint pain as well as one naproxen (500 mg)twice a day. (Naproxen is the active ingredient inNaprosyn.* It’s often prescribed for arthritis.)

For more information call 1-866-864-2600 or visit www.BEXTRA.com

Please see brief summary of important Product Information on page 54.

In addition to staying active, knowing how BEXTRAcan help relieve arthritis joint pain will give you apowerful edge.

*A registered trademark of Roche Laboratories Inc.

Festival Contact InformationFestival Contact Information

Sturgis Motorcycle RallyFor more information, visit www.sturgismotorcyclerally.com or call (605) 720-0800

Charleston Home and Garden ToursFor more information, visit www.preservationsociety.org/tour1.htm or call (800) 968-8175

Terlingua International Chili ChampionshipFor more information, visit www.chili.org/terlingua

Sundance Film FestivalFor more information, visit www.sundance.org. To order tickets or festival passes, call (877) SFF-TIXS

New Orleans Jazz and Heritage FestivalFor more information, visit www.nojazzfest.com. To find out about special festival packages, call (800) 380-FEST

50 PERFORM

64342_B.r3 2/10/05 3:12 PM Page 50

Page 27: Perform 3

PERFORM 53

Cartoons

THE L IGHTER S IDE

52 PERFORM

Quiz

THE L IGHTER S IDE

That’s it! Now look on page 53 and get to know yourself!

1. As I step outside on that glorious firstday of spring, I can’t help but think about:A. The beauty of the forsythia bloomsB. How I’m going to make my garden even better

this yearC. What fun a block party would beD. Getting work done on the yard and garden

2. The most important component of my idealspring dinner is:A. Delicious tasteB. Lots of fresh fruits and veggiesC. Great companyD. Someone else’s cooking

3. The best way to learn something new is to:A. Read a how-to bookB. Ask a teenagerC. Take a courseD. Consult an expert

4. When I wake up in the morning, I tend to:A. Lie still and try to remember my dreamsB. Leap out of bed and into the dayC. Do some gentle stretching exercises

and/or yogaD. Hope somebody brewed the coffee and

started breakfast

5. Just before I fall asleep, I often:A. Look forward to a pleasant dreamB. Think about what the next day will bringC. Do some deep-breathing exercisesD. I don’t remember—I just fall asleep

6. In planning a trip, I have to:A. Have peace and quietB. Visit someplace new and different C. Organize every detailD. Know a good travel agent

7.The classic tune that best describes my outlook on life is:A. “Imagine” by John LennonB. “My Way” by Frank SinatraC. “Bridge Over Troubled Water” by Simon

and GarfunkelD. “Satisfaction” by the Rolling Stones

8. I love:A. The Pillsbury DoughboyB. The Energizer BunnyC. Ronald McDonaldD. The Jolly Green Giant

9. If I were a pet instead of a human being, I’d most likely be a:A. SongbirdB. DogC. Tropical fishD. Cat

10. My favorite childhood TV show was:A. “The Adventures of Rocky and Bullwinkle”

B. “The Adventures of Superman”

C. “Captain Kangaroo”

D. “Mister Rogers’ Neighborhood”

Here’s a simple and fun way to discover a little bit about yourself. Take this quiz alone, or enjoy it with family and friends!

Select the letter that comes closest to describing your reaction to each of these ten situations. Enjoy!

10 to 20 points:You are a realist. You see things the way they are—and don’tlet yourself get caught up in details. You like to do things yourway and are not afraid to ask others for help when you thinkyou need it.

21 to 30 points:People like you for a very simple reason: you like people.They enjoy spending time with you and feel comfortable when you are around because you have the ability to acceptothers just as they are. You bring joy to friends and relatives.

31 to 40 points:Every day is just one more adventure for you to experience.You’re a doer, and you like things done right. Fortunately for you (and for everybody around you!), your charm and talents bring out the best in others.

41 to 50 points:You are an optimist—you help others believe that, as terrific as today is, tomorrow is bound to be even better. And withyour influence, it often is! People respond to your creativesolutions to problems and appreciate your imagination.

Give yourself: 5 points for every “A” 4 points for every “B” 3 points for every “C” 1 point for every “D”

“Getting to Know You!” Results

GettingtoKnowYou!GettingtoKnowYou!

64342_B.r3 2/10/05 3:12 PM Page 52

Page 28: Perform 3

Talk to your doctor today about prescribing BEXTRA for the joint pain of arthritis

Visit www.BEXTRA.com to print your certificate for a FREE 7-day trial

www.BEXTRA.com

Important Information. BEXTRA is not for everyone. Prescription BEXTRA should not betaken if you’ve had allergic reactions to certain drugs called sulfonamides, aspirin or otherarthritis medicines or if you’ve had aspirin-sensitive asthma or are in late pregnancy. It is notrecommended if you have advanced kidney disease. Tell your doctor if you have kidney orliver problems. In rare cases, serious stomach problems such as bleeding can occur withoutwarning. Tell your doctor right away if you develop blisters in the mouth or a rash, as it canbe a sign of a serious skin reaction that may be life threatening. If you experience otherunusual symptoms while taking BEXTRA, tell your doctor immediately. The most common sideeffects are headache, abdominal pain, indigestion, upper respiratory infection, nausea anddiarrhea. Please see important Product Information on page 54.

Form a powerful partnership against joint pain…

Brief summary of prescribing information.

INDICATIONS AND USAGEFor relief of the signs and symptoms of osteoarthritis and adult rheumatoid arthritis. For the treatmentof primary dysmenorrhea.

CONTRAINDICATIONSBEXTRA should not be given to patients who have demonstrated allergic-type reactions to sulfonamides, patients with known hypersensitivity to valdecoxib or those who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs are possible in such patients (see WARNINGS – AnaphylactoidReactions, and PRECAUTIONS – Pre-existing Asthma).

WARNINGSGastrointestinal (GI) Effects - Risk of GI Ulceration, Bleeding, and Perforation: Serious GI toxicity(bleeding, ulceration and perforation of the stomach, small intestine or large intestine) can occur at anytime with or without warning symptoms in patients treated with NSAIDs. Minor GI problems such asdyspepsia are common and may also occur at any time during NSAID therapy. Therefore, physicians and patients should remain alert for ulceration and bleeding even in the absence of previous GI tract symptoms. Inform patients about the signs and symptoms of serious GI toxicity andthe steps to take if they occur. Only 1 in 5 patients who develop a serious upper GI adverse event onNSAID therapy is symptomatic. Upper GI ulcers, gross bleeding or perforation caused by NSAIDs occurin about 1% of patients treated for 3 to 6 months and 2-4% of patients treated for one year. These trendscontinue, thus increasing the likelihood of developing a serious GI event at some time during the courseof therapy. However, even short-term therapy is not without risk. Prescribe NSAIDs with extreme cau-tion in patients with a prior history of ulcer disease or GI bleeding. Most spontaneous reports of fatalGI events are in elderly or debilitated patients and therefore special care should be taken in treating thispopulation. For high risk patients, consider alternate therapies that do not involve NSAIDs. Studies haveshown that patients with a prior history of peptic ulcer disease and/or GI bleeding and who use NSAIDs have a greater than 10-fold higher risk for developing a GI bleed thanpatients with neither of these risk factors. Pharmacoepidemiological studies have identified several otherco-therapies or co-morbid conditions that may increase the risk for GI bleeding such as: treatment with oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, alco-holism, older age, and poor general health status. Serious Skin Reactions: Serious skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported through postmarketing surveillance inpatients receiving BEXTRA (see ADVERSE REACTIONS–Postmarketing Experience). Fatalities due toStevens-Johnson syndrome and toxic epidermal necrolysis have been reported. BEXTRA should be dis-continued at the first appearance of skin rash or any other sign of hypersensitivity.Anaphylactoid Reactions: In postmarketing experience, cases of hypersensitivity reactions (anaphylactic reactions and angioedema) have been reported in patients receiving BEXTRA (seeADVERSE REACTIONS–Postmarketing Experience). These cases have occurred in patients with andwithout a history of allergic-type reactions to sulfonamides (see CONTRAINDICATIONS). BEXTRAshould not be given to patients with the aspirin triad. This symptom complex typically occurs in asthmatic patients who experience rhinitis with or without nasal polyps, or who exhibit severe, potentially fatal bronchospasm after taking aspirin or other NSAIDs (see CONTRAINDICATIONS and PRECAUTIONS–Pre-existing Asthma). Seek emergency help in cases where an anaphylactoid reaction occurs.Advanced Renal Disease: Treatment with BEXTRA is not recommended in patients with advanced kidney disease, but if it is used, close monitoring of the patient’s kidney function is advisable.Pregnancy: Avoid BEXTRA in late pregnancy because it may cause premature closure of the ductus arteriosus.

PRECAUTIONSGeneral: BEXTRA Tablets cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. The pharmacological activity of valdecoxib in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions.Hepatic Effects: Borderline elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs, and notable elevations of ALT or AST (about three or more times the upper limit of normal) have been reported in approximately 1% of patients in clinical trials with NSAIDs. These lababnormalities may or may not change with continuing therapy. Rare cases of severe hepatic reactions,including jaundice and fatal fulminant hepatitis, liver necrosis and hepatic failure (some with fatal outcome) have been reported with NSAIDs. In controlled clinical trials of valdecoxib, the incidence of borderline (defined as 1.2- to 3.0-fold) elevations of liver tests was 8.0% for valdecoxib and 8.4% for place-bo, while approximately 0.3% of patients taking valdecoxib, and 0.2% of patients taking placebo, hadnotable (defined as greater than 3-fold) elevations of ALT or AST. A patient with symptoms and/or signssuggesting liver dysfunction, or in whom an abnormal liver test has occurred, should be monitored carefully for evidence of the development of a more severe hepatic reaction while on therapywith BEXTRA. Discontinue BEXTRA if clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur (e.g., eosinophilia, rash).Renal Effects: Long-term administration of NSAIDs has resulted in renal papillary necrosis and otherrenal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, NSAIDs may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which mayprecipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impairedrenal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state. Usecaution when initiating treatment with BEXTRA in patients with considerable dehydration. Rehydratepatients first and then start therapy with BEXTRA. Use caution in patients with pre-existing kidney disease. (See WARNINGS – Advanced Renal Disease.)Hematological Effects: Anemia is sometimes seen in patients receiving BEXTRA. Patients on long-term treatment with BEXTRA should have their hemoglobin or hematocrit checked if they exhibitany signs or symptoms of anemia. BEXTRA does not generally affect platelet counts, prothrombin time(PT), or partial thromboplastin time (PTT), and does not appear to inhibit platelet aggregation at indicated dosages. Fluid Retention and Edema: Fluid retention and edema have been observed in some patients takingBEXTRA. Use BEXTRA with caution in patients with fluid retention, hypertension, or heart failure.Preexisting Asthma: Due to the potential for cross reactivity, do not use BEXTRA in patients with aspirin-sensitive asthma because of the risk of severe bronchospasm, which can be fatal. Use with caution in patients with preexisting asthma.Information for Patients: Inform patients that BEXTRA can cause GI discomfort and, rarely, more serious GI side effects, which may result in hospitalization and even fatal outcomes; to be alert for thesigns and symptoms of ulcerations and bleeding, and seek medical advice should these be observed;to promptly report GI ulceration or bleeding, skin rash, weight gain, or edema; to stop therapy and seekimmediate medical attention if they experience the warning signs and symptoms of hepatotoxicity (e.g., nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness, and flu-like symptoms); to seek immediate emergency help in the case of an anaphylactoid reaction; and to avoidBEXTRA in late pregnancy due to potential premature closure of the ductus arteriosus.Laboratory Tests: Physicians should monitor for signs and symptoms of GI bleeding.Drug Interactions: The drug interaction studies with valdecoxib were performed with both valdecoxiband a rapidly hydrolyzed intravenous prodrug form. The results from trials using the intravenous prodrug are reported in this section as they relate to the role of valdecoxib in drug interactions. General:In humans, valdecoxib metabolism is predominantly mediated via CYP 3A4 and 2C9 with glucuronidation being a further (20%) route of metabolism. In vitro studies indicate that valdecoxib is amoderate inhibitor of CYP 2C19 (IC50 = 6 µg/mL or 19 µM) and 2C9 (IC50 = 13 µg/mL or 41 µM), anda weak inhibitor of CYP 2D6 (IC50 = 31 µg/mL or 100 µM) and 3A4 (IC50 = 44 µg/mL or 141 µM).Aspirin: Concomitant administration of aspirin with valdecoxib may result in an increased risk of GIulceration and complications compared with valdecoxib alone. Because of its lack of anti-platelet effect,

valdecoxib is not a substitute for aspirin for cardiovascular prophylaxis. In a parallel group drug interaction study comparing the intravenous prodrug form of valdecoxib at 40 mg BID (n=10) vs placebo (n=9), valdecoxib had no effect on in vitro aspirin-mediated inhibition of arachidonate- or collagen-stimulated platelet aggregation. Methotrexate: Valdecoxib 10 mg BID did not show a significant effect on the plasma exposure or renal clearance of methotrexate. ACE-inhibitors: Reportssuggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. This interaction shouldbe given consideration in patients taking BEXTRA concomitantly with ACE-inhibitors. Furosemide:Clinical studies, as well as post-marketing observations, have shown that NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis. Anticonvulsants (Phenytoin): Steady state plasma exposure(AUC) of valdecoxib (40 mg BID for 12 days) was decreased by 27% when coadministered with multiple doses (300 mg QD for 12 days) of phenytoin (a CYP 3A4 inducer). Patients already stabilized onvaldecoxib should be closely monitored for loss of symptom control with phenytoin coadministration. Valdecoxib did not have a statistically significant effect on the pharmacokinetics ofphenytoin (a CYP 2C9 and CYP 2C19 substrate). Drug interaction studies with other anticonvulsantshave not been conducted. Routine monitoring should be performed when therapy with BEXTRA is eitherinitiated or discontinued in patients on anticonvulsant therapy. Dextromethorphan: Dextromethorphanis primarily metabolized by CYP 2D6 and to a lesser extent by 3A4. Coadministration with valdecoxib (40 mg BID for 7 days) resulted in a significant increase in dextromethorphan plasma levels suggestingthat, at these doses, valdecoxib is a weak inhibitor of 2D6. Even so, dextromethorphan plasma concentrations in the presence of high doses of valdecoxib were almost 5-fold lower than those seen inCYP 2D6 poor metabolizers suggesting that dose adjustment is not necessary. Lithium: Valdecoxib 40mg BID for 7 days produced significant decreases in lithium serum clearance (25%) and renal clearance(30%) with a 34% higher serum exposure compared to lithium alone. Lithium serum concentrationsshould be monitored closely when initiating or changing therapy with BEXTRA in patients receiving lithium. Lithium carbonate (450 mg BID for 7 days) had no effect on valdecoxib pharmacokinetics.Warfarin: The effect of valdecoxib on the anticoagulant effect of warfarin (1 - 8 mg/day) was studied inhealthy subjects by coadministration of BEXTRA 40 mg BID for 7 days. Valdecoxib caused a statistically significant increase in plasma exposures of R-warfarin and S-warfarin (12% and 15%,respectively), and in the pharmacodynamic effects (prothrombin time, measured as INR) of warfarin.While mean INR values were only slightly increased with coadministration of valdecoxib, the day-to-dayvariability in individual INR values was increased. Anticoagulant therapy should be monitored, particularly during the first few weeks, after initiating therapy with BEXTRA in patients receiving warfarinor similar agents. Fluconazole and Ketoconazole: Ketoconazole and fluconazole are predominantly CYP3A4 and 2C9 inhibitors, respectively. Concomitant single-dose administration of valdecoxib 20 mg withmultiple doses of ketoconazole and fluconazole produced a significant increase in exposure of valdecoxib. Plasma exposure (AUC) to valdecoxib was increased 62% when coadministered with fluconazole and 38% when coadministered with ketoconazole. Glyburide: Glyburide is a CYP 2C9 substrate. Coadministration of valdecoxib (10 mg BID for 7 days) with glyburide (5 mg QD or 10 mg BID)did not affect the pharmacokinetics (exposure) of glyburide. Coadministration of valdecoxib (40 mg BID(day 1) and 40 mg QD (days 2-7)) with glyburide (5 mg QD) did not affect either the pharmacokinetics (exposure) or the pharmacodynamics (blood glucose and insulin levels) of glyburide.Coadministration of valdecoxib (40 mg BID (day 1) and 40 mg QD (days 2-7)) with glyburide (10 mg gly-buride BID) resulted in a 21% increase in glyburide AUC(0-12hr) and a 16% increase in glyburide Cmax lead-ing to a 16% decrease in glucose AUC(0-24hr). Insulin parameters were not affected. Because changes in glu-cose concentrations with valdecoxib coadministration were within the normal variability and individualglucose concentrations were above or near 70 mg/dL, dose adjustment for glyburide (5 mg QD and 10mg BID) with valdecoxib coadministration (up to 40 mg QD) is not indicated. Coadministration of gly-buride with doses higher than 40 mg valdecoxib (e.g., 40 mg BID) has not been studied. Omeprazole:Omeprazole is a CYP 3A4 substrate and CYP 2C19 substrate and inhibitor. Valdecoxib steady state plas-ma concentrations (40 mg BID) were not affected significantly with multiple doses of omeprazole (40 mgQD). Coadministration with valdecoxib increased exposure of omeprazole (AUC) by 46%. Drugs whoseabsorption is sensitive to pH may be negatively impacted by concomitant administration of omeprazole and valdecoxib. However, because higher doses (up to 360 mg QD) ofomeprazole are tolerated in Zollinger-Ellison (ZE) patients, no dose adjustment for omeprazole is recommended at current doses. Coadministration of valdecoxib with doses higher than 40 mg QDomeprazole has not been studied. Oral Contraceptives: Valdecoxib (40 mg BID) did not induce themetabolism of the combination oral contraceptive norethindrone/ethinyl estradiol (1 mg/0.035 mg combination, Ortho-Novum 1/35®). Coadministration of valdecoxib and Ortho-Novum 1/35® increasedthe exposure of norethindrone and ethinyl estradiol by 20% and 34%, respectively. Although there is little risk for loss of contraceptive efficacy, the clinical significance of these increased exposures in termsof safety is not known. These increased exposures of norethindrone and ethinyl estradiol should be takeninto consideration when selecting an oral contraceptive for women taking valdecoxib. Diazepam:Diazepam (Valium®) is a CYP 3A4 and CYP 2C19 substrate. Plasma exposure of diazepam (10 mg BID)was increased by 28% following administration of valdecoxib (40 mg BID) for 12 days, while plasmaexposure of valdecoxib (40 mg BID) was not substantially increased following administration ofdiazepam (10 mg BID) for 12 days. Although the magnitude of changes in diazepam plasma exposurewhen coadministered with valdecoxib were not sufficient to warrant dosage adjustments, patients mayexperience enhanced sedative side effects caused by increased exposure of diazepam under this circumstance. Patients should be cautioned against engaging in hazardous activities requiring completemental alertness such as operating machinery or driving a motor vehicle.

Carcinogenesis, mutagenesis, impairment of fertility: Valdecoxib was not carcinogenic in rats givenoral doses equivalent to approximately 2- to 6-fold human exposure at 20 mg QD as measured by theAUC(0-24hr) or in mice given oral equivalent to approximately 0.6- to 2.4-fold human exposure at 20 mg QDas measured by the AUC(0-24hr) for two years. Valdecoxib was not mutagenic in an Ames test or a mutation assay in Chinese hamster ovary (CHO) cells, nor was it clastogenic in a chromosome aberrationassay in CHO cells or in an in vivo micronucleus test in rat bone marrow. Valdecoxib did not impair malerat fertility at oral doses equivalent to approximately 3- to 6-fold human exposure at 20 mg QD as measured by the AUC(0-24hr). In female rats, a decrease in ovulation with increased pre- and post- implantation loss resulted in decreased live embryos/fetuses at doses equivalent to approximately2-fold human exposure at 20 mg QD as measured by the AUC(0-24hr) for valdecoxib. The effects on female fertility were reversible. This effect is expected with inhibition of prostaglandin synthesis and is not theresult of irreversible alteration of female reproductive function.

Pregnancy: Teratogenic Effects: Pregnancy Category C. The incidence of fetuses with skeletal anomalies such as semi-bipartite thoracic vertebra centra and fused sternebrae was slightly higher in rab-bits at an oral dose equivalent to approximately 72-fold human exposures at 20 mg QD as measured bythe AUC(0-24hr)throughout organogenesis. Valdecoxib was not teratogenic in rabbits up to an oral dose equiv-alent to approximately 8-fold human exposures at 20 mg QD as measured by the AUC(0-24hr).Valdecoxib was not teratogenic in rats up to an oral dose equivalent to approximately 19-foldhuman exposure at 20 mg QD as measured by the AUC(0-24hr). There are no studies in pregnant women.However, valdecoxib crosses the placenta in rats and rabbits. Use BEXTRA during pregnancy only if thepotential benefit justifies the potential risk to the fetus. Non-Teratogenic Effects: Valdecoxib causedincreased pre- and post-implantation loss with reduced live fetuses at oral doses equivalent to approximately 19-fold human exposure at 20 mg QD as measured by the AUC(0-24hr) in rats and an oral doseequivalent to approximately 72-fold human exposure at 20 mg QD as measured by the AUC(0-24hr) in rabbitsthroughout organogenesis. In addition, reduced neonatal survival and decreased neonatal body weightwhen rats were treated with valdecoxib at oral doses equivalent to approximately 7-fold human exposure at 20 mg QD as measured by the AUC(0-24hr) throughout organogenesis and lactation period. Nostudies have been conducted to evaluate the effect of valdecoxib on the closure of the ductus arteriosusin humans. Therefore, avoid use of BEXTRA during the third trimester of pregnancy. Labor and Delivery:The effects of BEXTRA on labor and delivery in pregnant women are unknown. Nursing Mothers: It is notknown whether this drug is excreted in human milk. Because of the potential for adverse reactions in nurs-ing infants from BEXTRA, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother and the importanceof nursing to the infant. Pediatric Use: Safety and effectiveness of BEXTRA in pediatric patients belowthe age of 18 years have not been evaluated. Geriatric Use: No overall differences in effectiveness wereobserved between elderly patients and younger patients.

ADVERSE REACTIONSAdverse events occurring in >2.0% in controlled arthritis trials of three months or longer regardless of causality at doses of 10mg (N=1214) and 20 mg (N=1358) respectively: Hypertension1.6%/2.1%, Back pain 1.6%/2.7%, Edema peripheral 2.4%/3.0%, Influenza-like symptoms 2.0%/2.2%,

Injury accidental 4.0%/3.7%, Dizziness 2.6%/2.7%, Headache 4.8%/8.5%, Abdominal fullness2.1%/1.9%, Abdominal pain 7.0%/8.2%, Diarrhea 5.4%/6.0%, Dyspepsia 7.9%/8.7%, Flatulence2.9%/3.5%, Nausea 7.0%/6.3%, Myalgia 2.0%/1.9%, Sinusitis 2.6%/1.8%, Upper Respiratory TractInfection 6.7%/5.7%, Rash 1.4%/2.1%. 7.5% of arthritis patients receiving valdecoxib 10 mg daily, 7.9% of patients receiving valdecoxib 20 mg daily and 6.0% of patients receiving placebo discontinued due to adverse events in placebo and active controlled clinical trials. Inthe seven controlled OA and RA studies, the following adverse events occurred in 0.1–1.9% of patientstreated with BEXTRA 10–20 mg daily, regardless of causality: Application site disorders: Cellulitis, dermatitis contact; Cardiovascular: Aggravated hypertension, aneurysm, angina pectoris, arrhythmia,cardiomyopathy, congestive heart failure, coronary artery disorder, heart murmur, hypotension; Central,peripheral nervous system: Cerebrovascular disorder, hypertonia, hypoesthesia, migraine, neuralgia,neuropathy, paresthesia, tremor, twitching, vertigo; Endocrine: Goiter; Female reproductive:Amenorrhea, dysmenorrhea, leukorrhea, mastitis, menstrual disorder, menorrhagia, menstrual bloating,vaginal hemorrhage; Gastrointestinal: Abnormal stools, constipation, diverticulosis, dry mouth, duodenal ulcer, duodenitis, eructation, esophagitis, fecal incontinence, gastric ulcer, gastritis, gastroenteritis, gastroesophageal reflux, hematemesis, hematochezia, hemorrhoids, hemorrhoids bleeding, hiatal hernia, melena, stomatitis, stool frequency increased, tenesmus, tooth disorder, vomiting; General: Allergy aggravated, allergic reaction, asthenia, chest pain, chills, cyst NOS, edema gen-eralized, face edema, fatigue, fever, hot flushes, halitosis, malaise, pain, periorbital swelling, peripheral pain; Hearing and vestibular: Ear abnormality, earache, tinnitus; Heart rate and rhythm:Bradycardia, palpitation, tachycardia; Hemic: Anemia; Liver and biliary system: Hepatic function abnormal, hepatitis, ALT increased, AST increased; Male reproductive: Impotence, prostatic disorder;Metabolic and nutritional: Alkaline phosphatase increased, BUN increased, CPK increased, creatinineincreased, diabetes mellitus, glycosuria, gout, hypercholesterolemia, hyperglycemia, hyperkalemia, hyper-lipemia, hyperuricemia, hypocalcemia, hypokalemia, LDH increased, thirst increased, weight decrease,weight increase, xerophthalmia; Musculoskeletal: Arthralgia, fracture accidental, neck stiffness, osteoporosis, synovitis, tendonitis; Neoplasm: Breast neoplasm, lipoma, malignant ovariancyst; Platelets (bleeding or clotting): Ecchymosis, epistaxis, hematoma NOS, thrombocytopenia;Psychiatric: Anorexia, anxiety, appetite increased, confusion, depression, depression aggravated, insomnia, nervousness, morbid dreaming, somnolence; Resistance mechanism disorders: Herpes sim-plex, herpes zoster, infection fungal, infection soft tissue, infection viral, moniliasis, moniliasis genital, otitis media; Respiratory: Abnormal breath sounds, bronchitis, bronchospasm, coughing, dyspnea, emphysema, laryngitis, pneumonia, pharyngitis, pleurisy, rhinitis; Skin and appendages: Acne,alopecia, dermatitis, dermatitis fungal, eczema, photosensitivity allergic reaction, pruritus, rash erythematous, rash maculopapular, rash psoriaform, skin dry, skin hypertrophy, skin ulceration, sweating increased, urticaria; Special senses: Taste perversion; Urinary system: Albuminuria, cystitis, dysuria, hematuria, micturition frequency increased, pyuria, urinary incontinence, urinarytract infection; Vascular: Claudication intermittent, hemangioma acquired, varicose vein; Vision:Blurred vision, cataract, conjunctival hemorrhage, conjunctivitis, eye pain, keratitis, vision abnormal;White Cell and RES Disorders: Eosinophilia, leukopenia, leukocytosis, lymphadenopathy, lymphangitis, lymphopenia. Other serious adverse events that were reported rarely (estimated <0.1%) in clinical trials, regardlessof causality, in patients taking BEXTRA: Autonomic nervous system disorders: Hypertensiveencephalopathy, vasospasm; Cardiovascular: Abnormal ECG, aortic stenosis, atrial fibrillation, carotidstenosis, coronary thrombosis, heart block, heart valve disorders, mitral insufficiency, myocardial infarction, myocardial ischemia, pericarditis, syncope, thrombophlebitis, unstable angina, ventricular fibrillation; Central, peripheral nervous system: Convulsions; Endocrine: Hyperparathyroidism; Femalereproductive: Cervical dysplasia; Gastrointestinal: Appendicitis, colitis with bleeding, dysphagia,esophageal perforation, gastrointestinal bleeding, ileus, intestinal obstruction, peritonitis; Hemic:Lymphoma-like disorder, pancytopenia; Liver and biliary system: Cholelithiasis; Metabolic: Dehydration;Musculoskeletal: Pathological fracture, osteomyelitis; Neoplasm: Benign brain neoplasm, bladder carcinoma, carcinoma, gastric carcinoma, prostate carcinoma, pulmonary carcinoma; Platelets (bleedingor clotting): Embolism, pulmonary embolism, thrombosis; Psychiatric: Manic reaction, psychosis; Renal:Acute renal failure; Resistance mechanism disorders: Sepsis; Respiratory: Apnea, pleural effusion, pulmonary edema, pulmonary fibrosis, pulmonary infarction, pulmonary hemorrhage, respiratory insufficiency; Skin: Basal cell carcinoma, malignant melanoma; Urinary system: Pyelonephritis, renal calculus; Vision: Retinal detachment.

Postmarketing Experience: The following reactions have been identified during postmarketing use of BEXTRA. These reactions have been chosen for inclusion either due to their seriousness, reporting frequency, possible causal relationship to BEXTRA, or a combination of these factors. Because these reac-tions were reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency or establish a causal relationship to drug exposure.General: Hypersensitivity reactions (including anaphylactic reactions and angioedema)Skin and appendages: Erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxicepidermal necrolysis

OVERDOSAGESymptoms following acute NSAID overdoses are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain, which are generally reversible with supportive care. Gastrointestinalbleeding can occur. Hypertension, acute renal failure, respiratory depression and coma may occur, butare rare. Anaphylactoid reactions may occur following an overdose. Manage patients by symptomaticand supportive care following an NSAID overdose. There are no specific antidotes. Dialysis is unlikelyto be useful in overdose. Forced diuresis, alkalinization of urine, or hemoperfusion may not be useful.

DOSAGE AND ADMINISTRATIONOsteoarthritis and Adult Rheumatoid Arthritis - 10 mg once daily.Primary Dysmenorrhea - 20 mg twice daily, as needed.

HOW SUPPLIEDBEXTRA Tablets 10 mg are white, film-coated, and capsule-shaped, debossed “10” on one side with afour pointed star shape on the other, supplied as:NDC Number Size0025-1975-31 Bottle of 1000025-1975-51 Bottle of 5000025-1975-34 Carton of 100 unit doseBEXTRA Tablets 20 mg are white, film-coated, and capsule-shaped, debossed “20” on one side with afour pointed star shape on the other, supplied as:NDC Number Size0025-1980-31 Bottle of 1000025-1980-51 Bottle of 5000025-1980-34 Carton of 100 unit doseStore at 25˚C (77˚F); excursions permitted to 15-30˚C (59-86˚F). [See USP Controlled RoomTemperature]Rx only May 2004Manufactured for:

G.D. Searle LLCA subsidiary of Pharmacia CorporationChicago, IL 60680 USAPfizer IncNew York, NY 10017, USA

by: Searle Ltd. Caguas, PR 00725

bexb1002.c1102 B-4-S

© 2004 Pfizer Inc.

BEXTRA®(valdecoxib tablets)

64342_B.r3 2/10/05 3:13 PM Page 54

Page 29: Perform 3

“The race is not always to the swift...but to those who keep on running.”

“Act as if it were impossible to fail.”

“We come to feel as we behave.”

““I bend but do not brI bend but do not break.eak.””

“Forever is composed of nows.”

–Author Unknown

–Dorothy Broude

–Paul Pearsall

––Jean de La FJean de La Fontaine ontaine

–Emily Dickinson

“I bend but do not break.” –Jean de La Fontaine

Proud to support individualsliving life in the moment.

B E XTR A . c om

Printed in the USA/June 2004© 2004 Pfizer Inc. All rights reserved.BX180682A

64342_B.r3 2/10/05 3:14 PM Page 56


Recommended