PeroxideFormingChemicalsChemicalClassStandardOperatingProcedure
Rev.Date:2017-03-28
PeroxideFormingChemicals(PFCs)
Examples:Tetrahydrofuran,Diethylether,Isopropylether,Acetaldehyde,Styrene
FormorePFCs,seeAppendix
ThisSOPisnotasubstituteforhands-ontraining.
PrintacopyandinsertintoyourlaboratorySOPbinder.
Department: Chemistry
DateSOPwaswritten: Thursday,March23,2017
DateSOPwasapprovedbyPI/labsupervisor: Friday,March24,2017
PrincipalInvestigator:Name:F.Fischer
Signature:______________________________
InternalLabSafetyCoordinatororLabManager:Name:StephenvonKugelgen
LabPhone:510.301.1058
OfficePhone:510.642.8252
EmergencyContact:Name:StephenvonKugelgen
PhoneNumber:510.301.1058
Location(s)coveredbythisSOP: TanHall674,675,676,679,680,683,684
1.Purpose
ThisSOPcoverstheprecautionsandsafehandlingproceduresfortheuseofPeroxideFormingChemicals(PFCs).
ForalistPFCscoveredbythisSOPandtheiruse(s),seethe“ListofChemicals”.ProceduresdescribedinSection12applytoallmaterialscoveredinthisSOP.Achangetothe“ListofChemicals”doesnotconstituteachangeintheSOPrequiringrevieworretraining.Ifyouhavequestionsconcerningtheapplicabilityofanyrecommendationorrequirementlistedinthisprocedure,contactthePrincipalInvestigator/LaboratorySupervisororthecampusChemicalHygieneOfficeratucbcho@berkeley.edu
2.Physical&ChemicalProperties/DefinitionofChemicalGroup
Peroxideformingchemicalsareusuallyflammable,andallmayformexplosiveperoxides.
Awidevarietyoforganiccompoundsspontaneouslyformperoxidesbyafreeradical
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reactionofthehydrocarbonwithmolecularoxygen.Undernormalstorageconditions,formedperoxidescanaccumulateinthechemicalcontainerandmayexplodewhensubjectedtoheat,light,frictionormechanicalshock.
Organicfunctionalgroupslikelytoformperoxidesinclude:
• Ethersandacetals• Alkenesandallylichydrogen• Chloroalkenesandfluoroalkenes• Vinylhalides,esters,ethers• Dienes• Vinylalkyneswithαhydrogen• Alkylalkyneswithαhydrogen• Alkylareneswithtertiaryαhydrogen• Alkanesandcycloalkaneswithtertiaryhydrogen• Acrylatesandmethacrylates• Secondaryalcohols• Ketoneswithαhydrogen• Aldehydes• Ureas,amides,andlactamswithαhydrogenonacarbonattachedtonitrogen
3.PotentialHazards/Toxicity
PFCsarechemicalsthatwhenexposedtoairmayproduceunstableanddangeroushydroperoxideandperoxidesproductsovertime.
PFCsmayalsohaveotherhazardouspropertiesincludingtoxicity.Safeuserequiresassessingallpotentialhazards.
ItisthePrincipal Investigator’s responsibility toensureactivity-specific laboratoryproceduresand/orprocessesaretakenintoaccountwhenusingthisChemicalClassSOP.Please,reviewtheSDSofanychemicalbeforeuse(seeSection11–SDSLocation).
4.EngineeringControls
Lab-specificinformationonengineeringcontrolsmaybeincludedintheProtocol/Proceduresection.ThefollowingisthesetofengineeringcontrolsrequiredwhenhandlingPFCs:
• WorkwithPFC–theworkmustbeconductedinafumehoodunlessothercontrolsaredesignatedinthelab-specificProtocol/Proceduresection.Sashheightmustbekeptaslowaspossibletoavoidescapingfumesandprovideaphysicalbarrier.
• LaboratoriesandroomswherePFCsareusedmusthavegeneralroomventilationthatisnegativepressurewithrespecttothecorridorsandexternalenvironment.Thelaboratory/roomdoormustbekeptclosedatalltimes.
5PersonalProtectiveEquipment
Ataminimum,thefollowingPPEmustbewornatalltimes.EyeandFaceProtection
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A. ANSIZ87.1-compliantsafetyglasseswithsideshields,orchemicalsplashgoggles.
• Ordinary prescription glasses will NOT provide adequate protection unless they alsomeetANSIstandardandhavecompliantsideshields.
B. Ifthepotentialforexplosion/splashingexists,andadequatecoverageisnotprovidedbythehoodsash,afaceshieldmustbeworn.
SkinandBodyProtection
1. Glovesarerequiredwhenhandlinghazardouschemicals.• RefertospecificchemicalSDSforinformationongloveselection.• Foradditionalinformationongloveselection,goto:
http://ehs.berkeley.edu/hs/63-laboratory-safety/94-glove-selection-and-usage.html2. Labcoatsarerequiredwhenhandlinghazardouschemicalsinthelab.Selectthetypeoflabcoat
accordingtothehazardsatthespecificworkplace.3. Longpants,closed-toe/closed-heelshoes,coveredlegs,andankles.
RespiratoryProtection
RespiratoryprotectionisnormallynotrequiredforUCBerkeleylaboratoryactivities.Anylabpersonnelconsideringtheuseofarespirator(e.g.N-95respirator,dustmask)mustcontactEH&Sforaworkplaceassessment.
6.FirstAidProceduresandMedicalEmergencies
Intheeventofaninjury,notifyyoursupervisorimmediatelyandEH&Swithin8hours.
GototheOccupationalHealthFacility(TangHealthCenter,oncampus); ifafterhours,gotothenearestemergencyroom(AltaBates,2450AshbyAveinBerkeley);or
Call911(fromacellphone:510-642-3333)if:
• itisalifethreateningemergency;or
• younotareconfidentinyourabilitytofullyassesstheconditionsoftheenvironmentand/orthe condition of the contaminated/injured person, or you cannot be assured of your ownsafety;or
• thecontaminated/injuredpersonisnotbreathingorisunconscious.
Please remember to provide a copy of the appropriate manufacturer SDS (if available) to theemergency responders or physician. At a minimum, be ready to provide the identity/name of anyhazardousmaterialsinvolved.
IncaseofskincontactIfskincontactoccurs,and/orskinorclothingareonfire,immediatelydrenchinthesafetyshowerwithcopiousamountsofwaterfornolessthan15minutestoremoveanyremainingcontaminants.Ifpossibletodosowithoutfurtherinjury,removeanyremainingjewelryorclothing.IncaseofeyecontactRinsethoroughlywithplentyofwaterusinganeyewashstationforatleast15minutes,occasionallyliftingtheupperandlowereyelids.Removecontactlensesifpossible.Ifswallowed
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DoNOTinducevomitingunlessdirectedotherwisebytheSDS.Nevergiveanythingbymouthtoanunconsciousperson.Rinsemouthwithwater.IfinhaledMoveintofreshair.Needlestick/punctureexposureWashtheaffectedareawithantisepticsoapandwarmwaterfor15minutes.
7.SpecialHandling,Storage,TestingandDisposalRequirements
Lab-specificinformationonhandlingandstoragemaybeincludedinSection12-Protocol/Procedure.
PrecautionsforSafeHandling:
• LabeleachcontainerwiththeDateReceived,DateOpenedandDateLastTested.• TestchemicalsforperoxidebeforeanydistillationorpurificationofPFCs.• Donotallowtoevaporatetoneardrynessunlessabsenceofperoxideshasbeenshown.When
possible,addanon-volatileorganiccompound(suchasmineraloil)todiluteanyperoxidesremainingafterdistillation.
• UseextremecautionbeforeconcentratingorpurifyingPFCsasmostexplosionsoccurduringtheseprocesses.
• PFCsmustbestoredintheiroriginalmanufacturer’scontainerwheneverpossible. Thisisveryimportantinthecaseofdiethyletherbecausetheironinthesteelshippingcontainersactsasaperoxideinhibitor.PFCsmustbestoredinsealed,air-impermeablecontainersandmustbekeptawayfromlight(lightcaninitiateperoxideformation).Darkamberglasswithatightfittingcapisappropriate.
• Keepawayfromsourcesofignition–Openflames(e.g.,Bunsenburner).Inparticular,takemeasurestopreventthebuild-upofheatorelectrostaticcharge.
• Eliminateorsubstituteforalesshazardousmaterialwhenpossible.• Designyourexperimenttousetheleastamountofmaterialpossibletoachievethedesired
result.• DonotexceedthescaleofproceduresspecifiedinProtocol/Proceduresectionwithoutapproval
ofthePI.• Verifyyourexperimentalset-upandprocedurepriortouse.• Knowthelocationofthenearesteyewash,safetyshowerandfireextinguisherbeforebeginning
work.• Uponleavingtheworkarea,removeanypersonalprotectiveequipmentwornandwashhands.• Attheendofeachproject,thoroughlydecontaminatetheworkareaaccordingtothematerial
beinghandled.
ConditionsforSafeStorageandShelfLife
• Peroxidestendtoforminmaterialsslowlyoverseveralmonthstoyears.Therefore,itisimperativethatresearchersareawareoftheageoftheirPFCs.
• PFCsmustbestoredintheiroriginalmanufacturer’scontainerwheneverpossible.MinimizeperoxideformationinethersandotherPFCbystoringintightlysealedcontainersinacoolplaceintheabsenceoflight.
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• SomePFCsmustbekeptunderinertatmosphere,butothersthatcontaininhibitorsrequireoxygentofunction.Refertomanufacturer’srecommendationforproperstorageofthosematerials.
• EachcontainerofaPFC,uponarrivalinthelaboratory,mustbedated.Itmustalsobedatedwhenopenedforthefirsttime. Speciallabels,providedbyEH&Sandattachedtothecontainer,areusedtorecordthesedates,asshownbelow.Additionally,datesoftestingmustbeaddedtothelabel.
VisualInspection
VisuallyinspectallPFCsbeforeanyoperation.
Forliquids:Evidenceofpossibleperoxideformationinliquidsincludes:
• Solidsorcrystalsareobservedineithertheliquid• SolidsorcrystalsareobservedaroundthecapofPFCs• Visiblediscoloration• Liquidstratification
Diethyletheriscommonlysoldinsteelcontainerswhichpreventsvisualinspectionoftheliquid.Therefore,diethylethercontainerswhoseageandusehistoryareunknownmustbeassumedtocontaindangerouslevelsofperoxidesandmustnotbedisturbed.
Forsolids:Evidenceofpossibleperoxideformationinsolids(potassiummetal,potassiumamide,andsodiumamide)includes:
• Formationofasurfacecrust(forexample,potassiummetalformsayellowororangesuperoxideatthesurface)
• Discolorationofthesolid
Evaluationofalkalimetalsandtheiramidesisbasedonvisualcriteriaonly.Thesesubstancesreactstronglywithwater,andtheSOPforhandlingwaterreactivematerials(WR)mustbefollowedforthesechemicals,aswellastheprecautionsdescribedinthisSOP.
Onlychemicalsthatpassvisualinspectionmustbetested.
TestingforPeroxides
• Researchersmustnevertestcontainersofunknownageororigin.Oldercontainersarefarmore
PeroxideFormingChemicalsChemicalClassStandardOperatingProcedure
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likelytohaveconcentratedperoxidesorperoxidecrystallizationinthecapthreadsandthereforecanpresentaserioushazardwhenopenedfortesting.
• NevertrytoforceopenarustedorstuckcaponacontainerofaPFC.
• AllPFCswhicharetobedistilledmustbetestedpriortodistillationregardlessofage.
ThemostconvenienttestmethodistheuseofperoxideteststripsmanufacturedbyAldrichandseveralothersuppliers;theymaybeobtainedfromEH&S.Stripsthatoffera1-100ppmperoxiderangeareusefulfordeterminingifthematerialisbelowthecontrolpointof100PPM. Othertestingmethodsareavailable.ContactEH&Sat642-3073formoreinformation.
Disposal
● APFCmustbedisposedofbytheendoftheexpirationdate,ortestedforperoxidecontent.● Assumethatcontainersthatexhibitanyunusualvisualcharacteristicscontaindangerous
levelsofperoxidesanddonotdisturbthecontainer.NotifyEH&S,whowillassistinthefurtherevaluation.Ifthereisanydoubtaboutthesafetyofhandlingachemicalcontainer,notifyEH&Simmediately.
● Anycontainerfoundtohaveaperoxideconcentrationgreaterthanorequalto100ppmmustbedisposeof.ContactEH&Sat642-3073forassistance.
● Materialswhichareolderthanthesuggestedshelflifebuthavebeentestedandhaveperoxideconcentrationslessthan100ppmmayberetainedbutmustbetestedatregularintervals(seemanufacturer’srecommendationforpropertestinganddisposal).
● Wastematerialsgeneratedmustbetreatedasahazardouswaste.● TheemptycontainermustberinsedthreetimeswithaCOMPATIBLEsolvent;leaveitopen
inthebackofthehoodovernight.Solventrinsesandwaterrinsemustbedisposedofashazardouswaste.
● Asanalternative,unrinsedemptycontainerscanbedisposedofthroughEH&Sashazardouswaste.Theunrinsedemptycontainersmustbecapped.
● Donotmixwithincompatiblewastestreams.● Decontaminationofcontainersinordertousethemforotherpurposesisnotpermitted.
8.SpillandAccidentProcedure
Spill–Assesstheextentofdanger;ifnecessaryrequesthelpbycalling911(fromacellphone:510-642-3333)foremergencyassistanceor510-642-3073fornon-lifethreateningsituations.Ifyoucannotassesstheconditionsoftheenvironmentwellenoughtobesureofyourownsafety,donotenterthearea.Ifpossiblehelpcontaminatedorinjuredpersons.Evacuatethespillarea.Avoidbreathingvaporsfromspill.Ifpossible,confinethespilltoasmallareausingaspillkitorabsorbentmaterial.Keepothersfromenteringcontaminatedarea(e.g.,usecautiontape,barriers,etc.).
• MinorSpill–Intheeventofaminorspill,ifthereisnopotentialforhazardouschemicalexposure,reportthespillto510-642-3073andproceedtocleanit,ifyouaretrained.Useappropriatepersonalprotectiveequipmentandclean-upmaterialforchemicalspilled.Doublebagspillwasteinclearplasticbags,labelandrequestpick-up.
• MajorSpill–Anyhazardouschemicalspillthatinvolveschemicalexposure,anychemicalspillthatduetosizeand/orhazardrequirescapabilitiesbeyondyourtraining,oranychemicalspillthatgivestheperception(becauseofodor,forexample)thattherehasbeenahazardousrelease.Call911or510-642-3073forassistance.
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9.CleaningandDecontamination
Lab-specificinformationondecontaminationmaybeincludedinSection12-Protocol/Procedure.
• WearingproperPPE,laboratoryworksurfacesmustbecleanedattheconclusionofeachprocedureandattheendofeachworkday.
• Decontaminateallequipmentbeforeremovingfromadesignatedarea.
10.HazardousWasteDisposal
LabelWaste
• Labelallwastecontainers.SeetheEH&SFactSheet,“HazardousWasteManagement”forgeneralinstructionsonproceduresfordisposingofhazardouswaste.
DisposeofWaste
• Disposeofregularlygeneratedchemicalwastewithin6months.
• ContactEH&Sat642-3073ifyouneedassistance.
11.SafetyDataSheet(SDS)Location
SDScanbeaccessedonlineathttp://ucsds.com
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12.Protocol/Procedure–PeroxideFormingChemicals(PFC)
Procedure/Use Scale EngineeringControls/Equipment
PPE(eye,face,gloves,clothing) ProcedureStepsandSpecialPrecautionsforthisProcedure
1.PFCusedasareagent.
Upto100gassuppliedinthereagentbottle.RemembertoobtainPIapprovalifhigherscaleisnecessary.Documentthisapprovalinyournotebook
Allreactionsusingthesematerialsmustbeperformedinaproperlyoperatingfumehoodwiththesashaslowaspossibleorinaninertatmosphereglovebox.Openflamesandpossiblesparkingandstaticelectricitymustbeavoidedwheneverpossible.BlastshieldisrequiredifaPFCmaybedistilledtodrynessorevaporatedtodryness.
Eyeprotection:WearANSIApprovedtight-fittingsafetygogglesorsafetyglasseswithsideshields.FaceProtection:Faceshieldsaretobeusedwhenthereisariskofsplashingorsprayingandthereisnoprotectionfromthehoodsash.HandProtection:Confirmcompatibilityofglovematerialwithchemicalbeingused.Generalguidance(unlessotherwisespecifiedinthespecificSDS):Nitrileglovesmustbeusedtopreventincidentalcontact.Forspillhandlingorforpotentialcontactwithlargerquantities,usedoublenitrileorheaviergaugenitrileorneoprenegloves.Glovesmustbeinspectedpriortouse.Washanddryhandsafteruse.Clothing:Wearlabcoat;full-lengthpantsorequivalent;andclose-toed,close-heeledshoes.
Donotallowtoevaporatetodrynessunlessabsenceofperoxideshasbeenshown.Chromatography,distillation,orevaporationofPFCsefficientlyremovesallstabilizers.Collectedfractionsandrotavapcondensatemustbetreatedasunstabilizedandshouldnotbestoredinairforprolongedperiods.
Notes AnydeviationfromthisSOPrequiresapprovalfromPI.
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Procedure/Use Scale EngineeringControls/Equipment
PPE(eye,face,gloves,clothing) ProcedureStepsandSpecialPrecautionsforthisProcedure
2.UsingPFCsassolventsinreactions,forextractions.
Upto2Lassuppliedinthereagentbottle.RemembertoobtainPIapprovalifhigherscaleisnecessary.Documentthisapprovalinyournotebook
Allreactionsusingthesematerialsmustbeperformedinaproperlyoperatingfumehoodwiththesashaslowaspossibleorinaninertatmosphereglovebox.Openflamesandpossiblesparkingandstaticelectricitymustbeavoidedwheneverpossible.BlastshieldisrequiredifaPFCmaybedistilledtodrynessorevaporatedtodryness.
Eyeprotection:WearANSIApprovedtight-fittingsafetygogglesorsafetyglasseswithsideshields.FaceProtection:Faceshieldsaretobeusedwhenthereisariskofsplashingorsprayingandthereisnoprotectionfromthehoodsash.HandProtection:Confirmcompatibilityofglovematerialwithchemicalbeingused.Generalguidance(unlessotherwisespecifiedinthespecificSDS):Nitrileglovesmustbeusedtopreventincidentalcontact.Forspillhandlingorforpotentialcontactwithlargerquantities,usedoublenitrileorheaviergaugenitrileorneoprenegloves.Glovesmustbeinspectedpriortouse.Washanddryhandsafteruse.Clothing:Wearlabcoat;full-lengthpantsorequivalent;andclose-toed,close-heeledshoes.
Donotallowtoevaporatetodrynessunlessabsenceofperoxideshasbeenshown.Ifarotaryevaporatorisused,useanopencoldtrapsystemtocondensethesolventvaporandventtheexhaustintothefumehood.Distillation/evaporationofPFCsefficientlyremovesallstabilizers.Collectedfractionsandrotavapcondensatemustbetreatedasunstabilizedandshouldnotbestoredinairforprolongedperiods.Pressurecanbebuiltupwhenthesesolventsareusedinclosedreactionvessels.Adequateventilation(e.g.pressurebubbleronSchlenkmanifold,oranequilibratingballoon)mustbeusedtopreventdangerousoverpressurization.Pressuremaybebuiltupwhenperformingextractions.Adequateventilation(openthevalvefrequentlyduringtheextraction)hastobeusedtopreventdangerousoverpressurization.Thevaporinsuchaprocessmustbereleasedinafumehood.Ifheated,thereactionapparatushastobefittedwithanadequatelysizedcondenserwithadequatecoolingtopreventevaporation.Coolanthoseshavetobesecuredwithhoseclampstothecondenserandtheoutlet.
Notes AnydeviationfromthisSOPrequiresapprovalfromPI.
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Procedure/Use Scale EngineeringControls/Equipment
PPE(eye,face,gloves,clothing) ProcedureStepsandSpecialPrecautionsforthisProcedure
3.UsingPFCsassolventsincolumnchromatography(CC)orthinlayerchromatography(TLC).
Upto2Lassuppliedinthereagentbottle.RemembertoobtainPIapprovalifhigherscaleisnecessary.Documentthisapprovalinyournotebook
Allreactionsusingthesematerialsmustbeperformedinaproperlyoperatingfumehoodwiththesashaslowaspossibleorinaninertatmosphereglovebox.Openflamesandpossiblesparkingandstaticelectricitymustbeavoidedwheneverpossible.BlastshieldisrequiredifaPFCmaybedistilledtodrynessorevaporatedtodryness.
Eyeprotection:WearANSIApprovedtight-fittingsafetygogglesorsafetyglasseswithsideshields.FaceProtection:Faceshieldsaretobeusedwhenthereisnoprotectionfromthehoodsashandariskofsplashingorsprayingexists.HandProtection:Confirmcompatibilityofglovematerialwithchemicalbeingused.Generalguidance(unlessotherwisespecifiedinthespecificSDS):Nitrileglovesmustbeusedtopreventincidentalcontact.Forspillhandlingorforpotentialcontactwithlargerquantities,usedoublenitrileorheaviergaugenitrileorneoprenegloves.Glovesmustbeinspectedpriortouse.Washanddryhandsafteruse.Clothing:Wearlabcoat;full-lengthpantsorequivalent;andclose-toed,close-heeledshoes.
Donotallowtoevaporatetodrynessunlessabsenceofperoxideshasbeenshown.ChromatographyandevaporationofPFCsefficientlyremovesallstabilizers.Collectedfractionsandrotavapcondensatemustbetreatedasunstabilizedandshouldnotbestoredinairforprolongedperiods.ColumnChromatography:collectfractionsofinterestandconcentrateasneeded.Ifmorethan2Loftotalsolventisrequiredfortheoperation,dispense,collect,andconcentratenomorethan2Latatime.Ifarotaryevaporatorisused,useanopencoldtrapsystemtocondensethesolventvaporandventtheexhaustintothefumehood.Afteruseinthecolumn,allowthesolventtoevaporatefromthepackingmaterialpriortoproperdisposalofthepackingmaterial.
Notes AnydeviationfromthisSOPrequiresapprovalfromPI.
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Procedure/Use Scale EngineeringControls/Equipment
PPE(eye,face,gloves,clothing) ProcedureStepsandSpecialPrecautionsforthisProcedure
4.UsingPFCsassolventsforcleaningglassware
Upto0.5Latatime.RemembertoobtainPIapprovalifhigherscaleisnecessary.Documentthisapprovalinyournotebook
Allreactionsusingthesematerialsmustbeperformedinaproperlyoperatingfumehoodwiththesashaslowaspossible.Openflamesandpossiblesparkingandstaticelectricitymustbeavoidedwheneverpossible.BlastshieldisrequiredifaPFCmaybedistilledtodrynessorevaporatedtodryness.
Eyeprotection:WearANSIApprovedtight-fittingsafetygogglesorsafetyglasseswithsideshields.FaceProtection:Faceshieldsaretobeusedwhenthereisnoprotectionfromthehoodsashandariskofsplashingorsprayingexists.HandProtection:Confirmcompatibilityofglovematerialwithchemicalbeingused.Generalguidance(unlessotherwisespecifiedinthespecificSDS):Nitrileglovesmustbeusedtopreventincidentalcontact.Forspillhandlingorforpotentialcontactwithlargerquantities,usedoublenitrileorheaviergaugenitrileorneoprenegloves.Glovesmustbeinspectedpriortouse.Washanddryhandsafteruse.Clothing:Wearlabcoat;full-lengthpantsorequivalent;andclose-toed,close-heeledshoes.
Glasswarerinsedwithisopropanoltodryitasafinalstepincleaningmaybeallowedtodryonadryingrackoutsidethefumehood.AllowglasswarerinsedwithotherPFCstodryinthefumehoodbeforeputtingaway.
Notes AnydeviationfromthisSOPrequiresapprovalfromPI.
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13.DocumentationofTraining(signatureofallusersisrequired)
• PriortoconductinganyworkwithPeroxideFormingChemicals,designatedpersonnelmustprovidetrainingtohis/herlaboratorypersonnelspecifictothehazardsinvolvedinworkingwiththespecificchemical(s)used,workareadecontamination,andemergencyprocedures.
• ThePrincipalInvestigatormustprovidehis/herlaboratorypersonnelwithacopyofthisSOPanda
copyoftheSDSprovidedbythemanufacturer.IhavereadandunderstandthecontentofthisSOP:
Name Signature Identification Date
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Appendix:ListofPeroxideFormingChemicals(non-exhaustivelist)ListA:Chemicalsthatformexplosivelevelsofperoxideswithoutconcentration.Thesearethemosthazardousandcanformexplosiveperoxidelevelsevenifnotopened.Testforperoxideformationordiscardafter3monthsofreceivingthechemicals.Isopropylether Divinylacetylene PotassiummetalPotassiumamide Sodiumamide VinylidenechlorideDivinylether
ListB:Chemicalsthatformexplosivelevelsofperoxidesonconcentrationthroughdistillation,evaporation,orexposuretoairafteropening.Testforperoxideformationordiscardafter12months.
Acetal Acetaldehyde Benzylalcohol2-Butanol Chlorofluoroethylene Cumene(isopropylbenzene)Cyclohexene 2-Cyclohexen-1-ol CyclopenteneDecahydronaphthalene(decalin) Diacetylene(butadiyne)(gas) DicyclopentadieneDiglyme Diethylether(ether) EthyleneglycoletheracetatesFuran 4-Heptanol 2-HexanolMethylacetylene(gas) 3-Methyl-1-butanol Methylisobutylketone4-Methyl-2-pentanol 2-Pentanol 4-Penten-1-ol1-Phenylethanol Tetrahydrofuran(THF) Tetrahydronaphthalene(tetralin)Vinylethers Secondaryalcohols DioxanesEthyleneglycoldimethylether(glyme) Methylcyclopentane
ListC:Chemicalsthatmayautopolymerizeasresultofperoxideformation.Testforperoxideformationordiscardafter12months
Acrylicacid Styrene AcrylonitrileTetrafluoroethylene(gas) Butadiene Vinylacetylene(gas)Chloroprene Vinylacetate Chlorotrifluoroethylene(gas)Vinylchloride(gas) Methylmethacrylate VinylpyridineChlorobutadiene Vinylidenechloride
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ListofChemicals
Chemical(s) Chemical(s) Chemical(s)–Use(s):1,2,3,4-Tetrahydronaphthalene 1,2-Dimethoxyethane 1,3-Butadiene1,4-Dioxane 2-(2-Butoxyethoxy)ethylacetate 2-(4-CHLOROPHENOXY)-N-(5-(3,4-
DICHLOROBENZYL)-1,3-2-Butoxyethylacetate 2-Ethoxyethanol 2-Ethoxyethylacetate2-Furylmethylketone 2-Methoxyethanol 3,4-Dihydro-2H-pyran4-Methyl-2-pentanone Acetal AcrylicacidAcrylonitrile Allylether AnetholeAnisole Butylglycidylether ChloroprenesolutionChlorotrifluoroethylene Cumene Cyclohexenecyclopentadiene Cyclopentene Decahydronaphthalene,mixtureof
cis+transdiacetylene(gas) Dibenzylether DibutyletherDicyclopentadiene Diethylether DiethyleneglycoldimethyletherDiisopropylether Dimethoxymethane DiphenyletherDipropylether divinylacetylene divinyletherEthylvinylether Ethyleneglycolbutylether FuranIsoamylether iso-butylether IsopropylalcoholMethylmethacrylate Methylcyclopentane p-Anisaldehydepotassiumamide Propyne SodiumamideStyrene Tetrafluoroethylene TetrahydrofuranVinylacetate vinylacetylene(gas) Vinylidenechloride