POSITIONS WANTED

Biomedical Eineer, PhD., M.S.E.E. Seeks resarchposition. Good physiology backpund with resarchcxperience mainly in the visual, vestibular and neuralsystems, but quite flexibk. Clinical postdoctoral andteaching cxperience. Box 37, SCIENCE.

Ph.D. I have 7 years of experincc in the diagnostcsindustry, as well as 3 years as a postdoctorate, and havetakn 20 products from the laboratory bench to thecustomes hands; with all that is ntailkd My back-ground indudes immunology, biocheniistry, recombi-nant DNA, and an ent e al spirit rm booing fora key position with a small or start-up company, thatwants to become a major player. Box 4, SCENCE.

POSITIONS WANTED

Physiologist, MD. Resch experience in nephrophys-iology (hemodynaniics, endorinology). Clinical experi-ence in general internal mecn Teaching expeienc mmedical physiology. Box 31, SCIENCE.

POSITIONS OPEN

THE UNIVERS1TY OF WISCONSIN-PLATIEVHLLE

DEPARTMENT OF BIOLOGY1 Univerty Plaza

Plattevill Wi 53818-3099The Department of Biology is soeeng applicants for a

tenure-track faut posiiom at the ASSISTANT PRO-FESSOR. vl to begn in fal 1988. Ph.D. in anatomyor zoology required. Tea responsibilities will in-dude comparatve anatomy, anatomy and physiobhistology, emb yolgy, phxysiobogy and fixsccourse. Salary isS25,?0 to $28,000. A strong commit-mnt toexcelnce in aduateteaching is required.The individual will be expectd to initate a researchprogram involving underuate students. Send curric-ulum vitac, sand tree letters ofrcom -tion to: hai , Search and Scr Cmby 15 April1988.An Affa Aion/Eqal Em .

Women a i e cou ed to .

ASSISTANT PROFESSOR IN FOODSThe Foods and Nutition Division soees applicants for

a 9-month, tenure-tack position sing 21 August1988. Responsibilities indude develping i entresearch prgram in an area of foods reerh, teachingand advising undergraduate and grdate s nPh.D. in foods, fod science, or dosely related fidd

roquired; teach expience, demonstrd researchp d curriculum vitae, research inteest

statement, ranscipts, and three letters ofrferenc by 1June 1988 to: Dr. Sharon Nickols, Director, School ofHuman Rsors and Family Studies, Univeriy of

inoi, 905 Sotth Goodwin Avenue, Urba, IL61801. The University ofIois is anAffimaieAationlEqua Oppwtunity Explyfr.

ASSISTANT PROFESSORPHARMACOLOGY-TENURE TRACK

The Faieigh S. Dickinson, Jr. Colkeg of DentalMedine secks a foil-time, tenure-ack assismt ofes-sor in its Deparnt ofPharcogy. Respobilitiesincude: Tching und a and graduate dentaland dental hygiene students; developi competitiveresearch programs, and serving on mmttes.

Requirements: Ph.D. in pharmacolgy, clinical degree(D.M.D., D.D.S.) or 2 years ofpdocoral eence.Submit curriclum vitae and three letters o recom-

mendation by 25 April 1988 to: Univrity mo-ment O Fice, airigh on Uni , 1060River Road, Teanc, NJ 07666.FDU is an Equal Opposnity/AJlnasive Actio Em-

ployff. M/F

ASSOCIATI DIREBCORFOR STATISTICAL STANDARDS AND

METHODOLOGYU.S. BUREAU OF THE CENSUSDEPARTMENT OF COMMERCEEqual Emplyment Opportunity Exmkrjer

Do you possess e in statistcs with manaeialskills? The Bureau ofthe s is seeking a mathemati-cal staiscian who has demonstrated a i compe-tcnce and tchnical skills to serve on the Exctve Saffof one of the nation's foremost statistical or niA Ph.D. in mathematics, statistics, or a rlted field is

.desirable.Salary is in the executive range ($65,994 to $77,500)

depending upon qualifications.citizenship is required.

For infonmation and application mateials, pkase call:Sara Overbagh or idaPs at 301-763-2116, orwrite:

Personnel DivisionU.S. Bureau of the Census

Room 3245-3Washington, DC 20233

POSITIONS OPEN

MARYVILLE COLLEGE (TENNESSEE)ASSISTANT PROFESSOR OF BIOLOGY

Tenure-track position available Septenber 1988, toteach in areas ofplant physiology, botany, microbiology,and ecology/cnvironmental st6dies in a 4-year, church-related liberal arts institution that emphasizes superiortaching. Some coursework in introductory biology formajors and in general education for non-majors is expect-ed. Fidd workin the Grcat Smoky Mountains s yencouraged. Ph.D. in bio (pl hasis), pntecology and syste cs or relatd area required; teach-ing experience prefrred. Central location in suburbanKnoxvill, near Oak Ridge and the Great Smoky Moun-tains, offiers extensive opportunities for research and fieldstudies. Send letter, curnculm vitae, and thre refernceletters by 18 April 1988, to: Dr. Robert Naylor,Chairman, Department of Bioloby and Chemi,MaryvilkCog Marvile TN 7801.EqualOpprtunity Ep .

ASISrANTPROFESSOR OF FISHERIESMA-1INE FISH/SHELLFISH ECOLOGY-Candidateswith demonstrabk xperse in harvest or culure ofcommerncdl eploitedstc willbe given preference.ASSISTANT PROFESSOR OF WILDLIFE

MANAGEMENT (POPUIATION ECOLOGYAND ORNITHOLOGY)-Candidates with a strongbackgund in mathematics, populai biology, apliedecology and/or pofessinal wildlifc expericncc will begiven special consideration.

Ph.D. in appropriaterelated field required and teach-ingaexpenrince at the university level preferred for bothpositions. Both positions are full-time, tenure-track, andsta fall 1988. Qualified candidates should submit aktter of application, curriculum vitae (induding reprintsof publications), a transcript ofacademic work, andthreeletters of recommen ion to: Dean Richard L. Riden-hour, College ofNaal euces Hmboldt StateUniveity, Arcata, CA 95521. Teephone: 707-8263561. Apilicaiion deadline: 1 188 fr ail papers.Humbl* tate Uniw*y ir a ql OpponAfir-m AcaionITikEIXEpyr.ASSISTANT PROFESSOR OF PHARMACOL-

OGYAND TOXICOLOGY. A foi-time, tenure-trackposition in biodmcal toxicology begning 1 Septem-br 1988. Candidates should have a doctoral degree intoxicolosy or rlatd field and 1 or 2 years ofpostdoor-al cxpenenoc. Pre will be given candidates whoemphasizc the application of in vitro techniques toproblems in toxicology, and who have experise in theareas of immunotoxicology, r e toxicoloy,molcular biolgy/genetcs, or edcnology. Apphcants should send curiculum vitae, a statement of re-search plans, and the names of three references to: Dr.Jame LIVelC, Chaimn, Search Commi U-92, School of Pharmacy, Univerity ofC t,Storr, CT 06268. An information packet on the Pro-gram in Biodmal Toxicology is availabkl by teke-phone: 2034864683. Scr ing of applications wiilfin 23 March 1988 and continuc until the position isfiled. (Search #8A245).

T;be Unxi'esiy of Coxneaicu is an Ajirmatie Acaion/Equa Opporuity Employer.HARVARD SCHOOL OF PUBLIC HEALTH

ASSISTANT ORASSOCIATE PROFESSOR

Applications are being accepted from persons withgraduiate training, postdoctora experience, and provenaccomplishment in nutrition or the following scinesrelated to nutrition: chemistry, biochemit, and phar-macology. Applicants must de ate te abilit todevelop an independent research proram and tea achemical approach to the bioogical effects of fiods andtheir constuents. Prrnce wil be g tcto andidaeswhose rsearch has a chemical or mocur orntation.It is hopd to make-an appointmnt as early as Septem-

E%pp=sion ofixterest is &aocueiyinveedi qual4edwomen and m ritya .Send curriclm vitae, a summary of past accomplish-

ments, a statement of foture interests i research andteaching, and the names and addresses ofthree refercesto:

Professor Peter GoldmanHarvard School of Public Healt

665 Hund AenAucBoston, MA 02115

SCIENCE, VOL. 239

PersonnelPlacement

SCENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

LINE CLASSIFIED ADVERTIN DEADLNES:Thursday. 10 a.m., 2 weeks prior to issue date (mailedon issue date).

POSflONS WANTED: 40t per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayrent requied. This rate is available only toindividumals seeking jobs.

UNE CLASSIFIED (POSIONS OPEN COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$38.00 per line; $380 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad cost:Structure ad copy on a separate page, on lines of 52characters and s aces. Include any desired heading.Each line of heading and/or extra line spaces, and allpartial lines (including centered reply infornation) arecounted as full lines. Ad titles icated within the textare printed in boldface caps and are only 32 charac-ters per Hne. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This is anapproximate cost ONLY: low for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POLICY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday ONE week prior to issue date. Cancellationsmust be in writing.

Send copy for all PosItIorn Waned ads and UneClasalfiad ads less than 1/6 page in size (39 lines) to:

SCIENCE Csaffled A1333 N Street, NW, Room 0

Wahhklon, DC 20005Telephoe: 202-3264Z555

Send copy for Frwtonal DIplay ads, 1/6 page andlarger, and all M e ads to:

SdhrajoAeaoclatee Inc.

No York NY I03Telphone: 212-730-1050

Blind ad replies should be addressed as follows:Box gsnum ber)

SCIENCE1333 H Stre, NW

Wahlngton, DC 20005

Ph.D. Bioogy (Enmol). Good PC, Fortran,nuth, wnrting, plant/insect identifion, phogaphyskils; 70 pap and entire book. Seek industy/universi-ty position. ames Scott, 60 Ets Stet, Lakewood, CO80226. Telphone: 303-2334568.

140

POSITIONS OPEN

ASSISTANT PROFESSORPLANT SYSTEMATICS-CORNELL UNIVERSITY

The L. H. Bailey Hortorium, a unit of the Division ofBiological Sciences and the New York State College ofAgriculture and Life Sciences, Cornell University, seeksapplicants for a tenure-track position in plant systematics,starting date negotiable. Seventy-five percent oftime willbe devoted to research and twenty-five pereent to teach-ing. The research effort includes developing and main-taining a vigorous, independent rcscarch program inplant systematics and assuming a leading role in theHortonum's special research program on the CukliatedFlora ofthe Unied Statas. Tcaching duties will emphasizethe taxonomy of cultivated plants, as well as assistance inteaching the introductory plant taxonomy course andparticipation in the Hortonum's graduate student pro-gram. The appointee must have a-h.D., and interest inthe taxonomy of cultivated and/or economically impor-tant plants. An interest in tropical plant groups is desir-able. Applicants should send their curriculum vitae,teaching experience, and a detailed statement of futureresearch interests, and arrangc to have four letters ofrecommendation sent to: Dr. Jeffrey J. Doyle, SearchCommittee Chair, L. H. Bailey Hortoriun, 467Mann Library Building, Cornell University, Ithaca,NY 14853. To be assured of receiving consideration,applications should be received by 2 May 1988. CoellUneity is an Equal OppertunitylAffirnnmActium Edu-cator and Employer.ASSISTANT PROFESSOR OF MEDICINE, Sec-

tion on Endocrinology and Metabolism, Bowman GraySchool ofMedicine ofWake Forest University, Winston-Salem, NC. Full-time faculty position for postdoctoralbasic scientist. Salary $30,000 to $34,000.

Significant research experience and record of scientificpublcation required in two areas: sex hormone physiolo-gy and plasma lipoprotei metabolism.Send curricula vitae by 1April 1988 to: Dr. Norman

E. Miller, Head, Section on Endocrinology and Me-tabolism, Bowman Gray School of Medane, 300South Hawthorne Road, Wimston-Salem, NC 27103.Affirmati ActionlEqual Opportunty Employer.

Department of Zoology anticipates two tenure-trackASSISTANT PROFESSORSHIPS for fall, 1988. (1)GENETICS/EVOLUTIONARY BIOLOGY. Seek-ing geneticist to explore population genetics and cvolu-tion in animal systems using modern analytical tech-niques. Must be able to effectively teach broad range ofevolutionary/genetic topics. (2) ESTUARINE ECOL-OGY. Must have interest in estuarnne systems. Preferencemay go to candidates working empirically with zoo-plankton/larval ecology and interested in interactionsamong populations. Minimum qualifications: Ph.D. inappropnate discipline. Salarycomn with qualifi-cations and experience. Candidates should exhibit com-mitment to teaching at undergraduate and graduatelevels, and evidence of strong research potential. Sendcurriculum vitae statement of research goals, and threeletters of reference by 11 April 1988 to: Peter F. Sale,Chair, Department of Zoology, University of NewHampshire, Durham, NH 03824. Non-citizens mustinclude current visa status. UNH is anAffirmativeAaionlEqual Emponnt Opportunity Emplyer.

ASSISTANT/ASSOCIATE PROFESSOR-Ten-ure-track, Department of Radiation Medicine-George-town University. Ph.D. with postdoctoral experience inmolecular biology (oncogenes and anti-oncogenes)-tojoin research group in radiation biology.

Send curriculum vitae to:Anatoly Dritchilo, M.D., ChairanDepartment of Radiation Medicine

Georgetown Univity Medical Center3800 Resoir Road, N.W.Washington, D.C. 20007

ASSOCIATE RESEARCH SCIENTIST: positionavailable immediately. Ph.D. with training in mycoplas-mology/molecular biology tojoin ongoing research teamstudying human pathic mycoplsmas and mycoplas-ma host interactions. expenience with current electronmicroscopy techniques helpful. Salary range: $25,000 to$30,000, based on experience. Send curriculum vitae andthree letters of reference to: Millicent Coker-Vann,Ph.D., 2455 Army Navy Drive, Arlington, VA22206.

ASSISTANT/ASSOCIATE PROFESSORS-Twotenure-track faculty positions in clinical laboratory sci-ences: (1) microbiologist or clinical laboratory scientistwith microbiology experience, certification in microbiol-ogy preferred; and (2) clinical laboratory scientist withexperience in molecular biology. Individuals will beexpected to conduct a strong research program, supevsegraduate students, and teach in the B.S. and M.S.programs. Ph.D. required and experience in health sci-ences education preferred. Rank and salary commensu-rate with experience. Submit curriculum vitae and threeletters of recommendation by 15 April 1988 to: Chair,Department of Health Sciences, School of AlliedHealth Professions, Unerity ofWisconsin (UWM),P.O. Box 413, Milwaukee, WI 53201. UWM is anAffirmatimeAcionEqual Opportunity Emplyer.

ASSOCIATE VICE PRESIDENTFACULTY AFFAIRS AND RESEARCHCALIFORNIA STATE UNIVERSITY,

HAYWARDResponsibilities: (i) fostering campus research and

faculty development and administerng sabbatical leavesand faculty exchanges, (ii) providing inormation and aidin grant and contract procurement, wnting, and submis-sion, (iii) coordinating campus research committees, and(iv) administering faculty personnel policies, studentgrievances and other assignments. The Associate VicePresident will be aided by a half-time Assistant VicePresident. Qualifications: Doctorate and significantteaching, administrative and research experience at theuniversity level and related to the requirements of theposition. A record of successful professional activity andresearch and a knowledge of funding mechanisms areexpected. Salary and fringe benefits are competitive.Expected appointment date is 15 June 1988. Applica-tions and/or nominations will begin to be considered 1April 1988; those received after I May 1988 cannot beassured consideration. Please direct al correspondenceto: Chair, Selection Committee for the Assodate VicePresident, Research and Faculty Affairs, c/o Office ofthe Provost, Califomia State University, Hayward,Hayward, CA 94542-3007. An Equa OppounitylAffirmative Ain Employer. Women and ethnic minotyfizculty are especially encouraged to apply.

STANFORD UNIVERSITYThc Department of Biological Sciences is searching for

a BEHAVIORAL ECOLOGIST at the level of assist-ant professor. We seek an ecologist whose interests focuson behavior. The successful candidate must have anoutstanding record of research. Tea n rsponsibilitieswill indude an undergraduate coursc in bchavioral ecolo-gy. Stanford Unieity is an Equal Opporunty Emplyer.Women and minority cadidates are aepecially invited toapply. Send curriculum vitae and the names of threereferences to: Behavioral Ecology Search Committee,Department of Biological Sciences, Stanford Univer-sity, Stanford, CA 94305-5020.

BIOCHEMIST/MOLECULAR BIOLOGIST. Atenure-track faculty position is available in the Depart-ment of Biological Chemistry, Dental Branch, The UJni-versity of Texas Health Science Center at Houston.Applicants should have a Ph.D., postdoctoral experience,and an active research p ram, preferably utilizingbiochemical or molecular biological techniques to studyproblems concerning mineralized or oral tissues. Theapplicant will be expected to develop an extramurallyfunded research program. Responsibilities include teach-ing dental and graduate students. Salary and rank will becommensurate with qualifications. Send curriculum vitaeand names of three references to: Dr. William T. Butler,Chairman, Department of Bioloical Chemistr,Dental Branch, The Univrsity of Texas Health Sci-ence Center, P.O. Box 20068, Houston, TX 77225.The University of Texas is an Equal Opporunty Employer.Women and minoritis are encuraged to apply.

BIOCHEMIST, PhJD.-CIBA Corning Diagnos-tics, in Irvine, California is seeking a Ph.D. with exper-ence in the stabilization ofenzymes and proteins. Hemo-globin experience helpful. Postdoctorate and/or industryexprience acceptable. Rdocato assistance provied.Qualfied applicants should send risumn with salary re-quirents to: Karen Kdl, Human Rs es Manag-er, 17395 Daimler Stret, Irvine, CA 92714. We arr anEqual Oppotuniy EmployerMVFIHIV Empler.

BIOCHEMISTSTenure-track faculty positions are available for candi-

dates interested in developing strong and independentresearch programs with long-term growth potential. Allareas will be considered, but emphasis will be in: largeDNA viruses; extracellular matrix molecular biology;dental biochemistry; molecular endocrinology. The De-partment of Biochemistry has excellent facilities and isundergoing substantial expansion. Teaching includesmedical, dental, and graduate students within a sizablemedical complex. Salary is commensurate with experi-ence. Curriculum vitae, brief statement of present andfuture research intercsts, and three letters ofrecommen-dation should be sent to: Dr. R D. Wells, Departmentof Biochenistry, The University of Alabama at Bir-mingam, Birmingh AL 35294.AnEqualOpportu-nty/AffiratveAtion Employer.

BIOLOGY: Two biologyFACULTYPOSMONS.Applications are invited for two assistant professor posi-tions beginning August, 1988 (Ph.D. required). (i)Microbiologist with expertise to teach related coursesincluding botany. (ii) Physiologist with expertise to tcachcomparative anatomy and related courses. Ability andwillingess to teach introductory biology required. Adedication to undergraduate education is essential. Xavi-er University is a small, Black, Catholic, liberal artsinstitution. Application deadline: 7 April 1988. Scndr6sumi and three letters of recommendation to: SearchCommittee, Biology Department, Xavir Umversity,New Orleans, LA 70125.

BIOLOGY-SABBATICAL REPLACEMENT.One-year appointment (late August 1988 to early May1989) at the assistant professor rank. Appropriate doc-torate required. Duties include teaching anatomy andphysiology, microbiology, pathophysiology, and non-majors general biology. Send letter ofresume by 15 April1988 to: William Putnam, Dean, School of NaturalSciences and Mathematics, Mesa College, GrandJunction, CO 81502. Mesa GClge is an AffirmativeActionlEqual Opportunity Emploer.

CELL BIOLOGIST-The Institute for Environ-mental Medicine ofthe University ofPennsylvania Medi-cal Center seeks a cell biologist for a tenure-track ap-pointment as assistant professor. Successful candidatewill establish an independent research program and willsupervise a core electron microscopy laboratory. Re-search areas of special interest include lipid-protein inter-actions, endocytosis, secretion, epithelial cell differentia-tion, macromolecular synthesis, and lipid peroxidation.Guaranteed salary support, a well-e9juipped laboratory,and generous start-up funds are available. Deadline forapplications is 15 May 1988. Send curriculum vitae andstatement of research interests to: Cell Biology SearchCommittee, c/o Maureen Doran, Executive Assistant,Institute for Environmental Mediane, University ofPennsylvania, One John Morgan Building, 36thStreet and Hamilton Walk, Philadelphia, PA 19104-6068. The Univerty ofPennsylvania is anEqual Opportu-nitylAffirmativeAtAion Employer.

The University of Illinois is searching for candidates toCHAIR THBE DEPARTMENT Of PATHOLOGYat its College of Medicine at Peoria. The Institution atPeoria, one of four regional sites, provides a program inmedical education for 160 M-2, M-3, and M-4 students.The College utilizes hospital-based pathologists to con-duct its undergraduate teaching program in pathology.Support for further departmental development is avail-ab[e. Candidates should have a record of excellence inteaching undergraduate medical students, a commitmcntto excellence in research and demonstrated administrativeabilities. Opportunities for service are availabk. Al-though an M.D. is preferred, candidates with a Ph.D. inpathology will be given serious consideration. Initialinquies will be confidential. Interested candidatesshould send curriculum vitae to: Phillip C. Jobe, Ph)D.,Pathology Search Commlittee, University of MllinoisCollege of Medicne at Peoria, Box 1649, Peoria, IL61656. Preference will be given to applications reccivedprior to 30 May 1988. The Univert ofIllinois is anEqualOppotunitylAffirmave Action Emplr.

PERSONNEL PLACEMENT 1441I8 MARCH I988

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

CELIDEVELOPMENTAL BIOLOGIST, non-tenure track, assistant professor level, beginning August1988. Ph.D. and strong interest in undergraduate teach-inm required. Collaborative research with members ofthecl biology group Ls encouraged. Send resumd and threelette of reterence by 1 April 1988 to: Dr. Kathy A.Suprenant, Department ofPhysiol and Cell Biolo-gy, University of Kansas, Lawce, KS 66045.Affir-matieA Eqa Opportunity Employer

CELLULAR IMMUNOLOGISTThe Department of General Surgery at Rush-Presby-

terian-St. Luke's Hospital of Rush University invitesapplications for a full-time position as assistant professorand associate scientist. Interested applicants must have anM.D. and/or Ph.D. degree with experience in basictumor and transplant immunology. Ongoing investiga-tions indude: phenotypic and functional characterizationof tumor-infiltrating leukocytes, therapeutic potential oflarge rularhocytes in bone marrow transplanta-tion, flow cytometric analysis of solid tumors, and pre-dictors of rejection in renal and hepatic transplantation.Qualitics of the successful applicant should indudc theability to pursue a research program bridging basiclaboratory investigaton with clinically relevant problemsin oncology an transplantation. Intcrested personsshould submit curriculum vitae and three lctters ofrecommendation to:

Steven G. Economou, M.D., irmanDepartment of General SurgeryRush-Presbyterian-St. L s

Medical Center1653 West Congress Parkway

Chicago, IL 60612

CHAIRMNDEPARTMENT OF BIOMEDICAL

ENGINEERINGUNVERSITY OF TENNESSEE, MEMPHISNominations and applications are invited for the posi-

tion of Chair of the newly created Deparm t ofBiomedical Engineering in the College of GraduateHealth Sciences beginnng summuer, 1988.

Candidates must possess a doctoral degree in biomedi-cal enipneering or in a related discipline, a demonstratedrecord of achievement in research and research trainingand in developing interdisciplinary programs in resmeac,service, and graduate education. The department headwill be expected to excrt inovativ leadership in mnnnew faculy lines ind two chairs of excclknce aswleas in the develo ofao ae grduat degeeprogram i Bidical Engin with the HerffCollegeof Enginering at Memps State niversity.

Application materials, induding ersum&s and thenames, addresses and telephone numbers of at least threerefcrences should be sent to:

Ray H. Cypess, DeanCollege of Grduate Health Sdcnces

62 South DunlapMemphis, TN 38163

Applications must be received by 15 April 1988, forfull consideration.

The Univerity of Tennessee is an Equal Opporunity/AffirmativeActon Employer.

CHAIRPERSON OFDEPARTMENT OF BIOLOGY

FOSTER G. McGAW ENDOWED CHAIRLake Forest College invites nominations or applica-

tions for the Position of Chairperson of the BiologyDepartment and Foster G. McGaw Chair in Biology.Candidates should present a strong record of teachingand scholarship and must be interested in involvingundergraduate students in research. Any subfield ofbiology tat is clearly an important element of a fineundergraduate program will be appropriate. The personappointed must demonstrate thei quality of kadershipthat will develop a distinguished biology department.The chairperson will have the opportunity to replacemost ofthe members ofthe department over the next fewyears. This appointment will be at a rank of msociateprofessor or professor. Send nominations or applicationswith names offour references to: BailgD n , Deanof the Faculty, Lake Forest Colkge, Lake Forest, IL60045. Lake Forest Clkge actvely encourages aplionsfim minorities and women.

CHAIRPERSONDEPARTMENT OF PSYCHIATRYUNIVERSITY OF ALABAMASCHOOL OF MEDICINE, UAB

The University ofAlabama School ofMedicine, UAB,is secking a person to fill the position of Chairperson,Department ofPsychiatry. The department is responsiblefor teaching medical students, residents, and graduatestudents in psychiatry and relevant areas of the neurosci-ences, as wellas conducting multidisciplinary research onpsychiatric disorders and related topics in the neurosci-ences. Patient care responsibilities indude a comprehen-sive mental health center, inpatient and outpatient serv-ices, as well as substance abuse programs. A certificate ofneed for a new 90-bed psychiatric hospital has recentlybeen obtained, and it is anticipated that construction ofthis facility will begin shortly.UAB is strongly committed to research. Its medical

research programs are undergirded by excellent basicscience de ts, facilities and state-of-the-art equip-ment and shared resources.

Inquiries and application should be received by 30June 1988, and should be addressed to:

Mrs. A. D. HycheOffice of the Dean

University ofAlabama School ofMedicineUAB Station

Birmingham, AL 35294An Affi reAction/Equ Opporunity Employr

DEVELOPMENTAL BIOLOGISTUNWERSITY OF CALIFORNIA, IRVINEThe Department of Developmental and Cell Biology,

University of California, Irvine, invites applications for atenure-track position in developmental biology at theassistant professor leve. The department currently hastwelve faculty working in tissue, cellular, or molecularaspects ofdevelopment. We are seeking candidates work-ing on molecular approaches to some aspect ofembryon-ic development. Candidates will be selected primarly onthe quality of their rescarch, as opposed to the specifictopic, but the department wishes to build strength insome specific areas, induding molecular genetic aspectsofpattern formation; molecular nature of cdl detemiina-tion; role of growth factors or oncogenes in develop-ment; and developmental neurobiology. Candidatesworking on any metazoan will be considered, but we areparticularly interested in adding someone working withmammals. The successful candidate will be expected todirect a vigorous, indepcndent, extramurally funded re-search program, to participate in the developmentalbiology graduate training program, and to teach at theundergraduate levl. Applicants should submit curricu-lum vitae, copies of significant recent reprints, andconcise statement of research accomplishments andplans, and arrange for three ktters ofreference to be sentto: Chair, Developmental Biology Search Committee,Department ofDevelopmental and Cell Biology, Uni-versity of Califomia, frie, CA 92717. Applicationsshould be received by 30 April 1988. The Ufnies ofCalifiwnia is an Equal Opprtunity/AffimatieAcation Em-player

DIRECTOROFFICE OF RADIATION SAFETY

Washington State University invites applications/nom-inations for the full-time, non-tenured track faculty posi-tion of Director, Office of Radiation Safety. Salary$35,000 to $45,000 per year. Position is available 1 July1988. Deadline for applications/nominations is 15 April1988.Candidates must hold a master's degree in the area of

health physics, nudear sciences, radiation safety or relat-ed area, have experience in handling ofand knowledge ofregulations relating to radioactive materials, and havecommunication skills. Ph.D. degree preferred and experi-ence in administtion andin daling with users and statecompliance officers desirable. Complete position descrip-tion available upon request.Send applications/nominations (induding curriculum

vitae and names of three references) to: Dr. Mack .Johnson, Assodcate Vice Provost forR rch, Wash-ington State Universit, Pullman, WA 99164-1030.Telephone: 509-335-3535.

Wathingeon State University is an Affirmative ActionlEqual Opportunity Eduator and Employer. Protectedgroupmemben are encouraged to apply and to ident thir status.

NATIONAL SCIENCE FOUNDATIONWashington, D.C. 20550

DIRECTOR, DIVISION OFINSTRUMENTATION AND RESOURCESNSF's Directorate for Biological, Behavioral and So-

cial Sciences is seeking qualified candidates for theposition of Director, Division of Instrumentation andResources. The Division coordinates support for infra-structure and research resources in the biological, behav-ioral, and social sciences. Emphasis is on multiusernstrumentaton, instrumnctation development, and bio-logical facilities. In addition, the Division coordinatesBBS cross-directorate programs and provides ADP sup-port for the divisions within the Directorate.This Senior Executive Service position, with a salary

range of ES-1 ($65,994) to ES4 ($73,400), is an-nounced on a career appointment basis. Applicants musthave a Ph.D. or equivalent experience in biophysics,structural biology or related discipline (e.g., biochemis-try, molecular biology); substantial research contribu-tions or innovative leadership in research administrationin the biological sciences; and the ability to achieveorganizational objectives through the supervision andmanagement of subordinates.

Applicants should contact: Margaret Cadenartorion 202-357-7601 (hearing impaired individuals maycall TDD 202-357-7492) to request Announcement EP88-2 fior complete qualification requirements and appli-cation procedures. Applications must bc received by 15April 1988.

Equal Opportunity Emplyer

DIRELCTOR OF STATEWIDE CYTOGENET-ICS PROGRAM. Board-certified or -eligible cytoge-neticist with experience and interest in molecular biologyto direct established cytogenetics laboratory and initiateplanning for a regional DNA lab. Primarily serviceobligations, but research strongly encouraged. The Cyto-genetics and Molecular Cell Biology Laboratory is aDivision in the Department of Medical Genetics/Mon-tana Medical Genetics Program. Faculty appointment atMontana State University possible. Salary commensuratewith training, experience and certification status. AnAffiative Acio/Equal Opportunity Employer. Contact:John M. Opitz, Shodair Hospital, Box 5539, Helena,MT 59604. Tdelphone 406-442-1980.

ECOLOGISTThe Department of Biological Sciences ofthe Univer-

sity ofPittsburgh is seeking an established scientist with astrong reputation in any branch of ecology. The success-ful candidate will help to develop the graduatc programin ecology and evolution, and will serve as Director ofthe Pymatuning Laboratory of Ecology, a well-equippedfield station located 100 miles north of Pittsburgh.Experience in generating external funding is important,and some administrative background would be desirable.The appointmcnt will bc made at the level of tenuredassociate or full professor, and will be available as early asSeptember, 1988. One or two junior appointments willbe made available in the next 2 years as a part of thisprogram expansion.

Applications should include curriculum vitae, copies ofrecent publications, a statement of rcsearch interests andfuture plans, and the names and addresses ofat least threepotential refercnces. Address applications to: EeologySearch Committ, Dep rt of Bioloial Sc s,Univrsity of Pitsh, Ps PA 15260. AnEqual Opprtniy Ai a n Emplyer.

ECOLOGISTThe Department of Biology of Loyola University of

Chicago, Lake Shore Campus, invites applications for a9-month, tenure-track position at the [evel of assistantprofessor. A Ph.D. is required; postdoctoral experience isdesirable. Individuals should be engaged in modern andimaginative research in experimenta aquatic ecology.The successful candidate will develop an active, funlddresearch program, direct graduate students, and teachundergraduate and graduate courses. Submit curriculumvitae, a description of r h interests, and three lettersof recommendation by 15 April 1988 to: Dr. RobertHamilton, Chairman, Search Committee, Depart-ment of Biology, Loyola University ofChiago, 6525North Sheridan Road, Chicago, IL 60626.An EquaOpporunity Employer.

SCIENCE, VOL. 239144-2

POSITIONS OPEN POSITIONS OPEN

Ann- ~BIOCHEMIST/DRUG

METABOLISMMarion Laboratories, Inc. is a dynamic compary in therapidly expanding health care industry. Due to our con-tinued growth and expansion, the Preclinical Drug Meta-bolism group of the Biological Affairs Department is seek-ing a Ph.D. Biochemist interested in performing animalstudies of disposition and pharmacokinetics of drugs inthe discovery and development. This position will belocated in Kansas City, Missouri.The successful candidate will have at least three yearsof experience in drug metabolism, pharmacokinetics anddrug analysis. Industry experience is desirable. The in-dividual must possess superior oral and written communi-cation skills to effectively interface with all levels ofmangementWe offer an excellent total compensation and benefitspackage including bonus, stock options, profit sharing,comprehensive group health, dental, and life insurance.Please send a detailed resume including salary historyin confidence to: RecrultIng & Placement, DepL P1KH,lP.O. Box 9627, Kansas City, MO 64134. Equal Oppor-tunity Emoplnyer.

LltntborUtories, Inc.The__COnapac

I

The Department of Cell Biology at Smith Klne & French Labom-tories, located near Valley Forge, Pennsylvania, is seeking a CellBiologist/Biochemist to join the Department of Cell Biology toinvestigate the expression, processing and secretion of heterolo-gous gene products in mammalian cells. Familiarity with anumber of biochemical and immunological techniques (e.g., 1-Dand 2-D gel electrophoresis, immunoprecipitation, epitope map-ping and nucleic acid hybridization) is essential.Candidates must have:* Ph.D. in Cell Biology/Biochemistry or Biology.* 0-2 years postdoctoral experience.We consider postdoctoral studies to be of major importance inan individual's career and encourage publication of findings inleading journals and full interaction with the scientificcommunity.We offer excellent compensation and benefits, and an attractiverelocation policy. For confidential consideration, send your cur-riculum vitae and the names of three references to: Ms. Barba-ra J. Schwartz, S0028, R&D Associate Employment Administra-tor, Department of Human Resources, Smith Kline & FrenchLaboratories, 709 Swedeland Road, King of Prussia, PA 19406-2799. We are an Equal Opportunity Employer, M/F/H/V.

CANCER IMMUNOBIOLOGYThe University of Texas Southwestem Medical Center at Dallas hasannounced a new Cancer Immunobiology Program under the director-ship of Dr. Ellen S. Vitetta. The plan is to develop the program into anew Center devoted to research on the immunobiology of cancer, withparticular focus on leukemia/lymphoma.The Program is located in a research complex that also houses theHoward Hughes Medical Institute, several other Centers conductingbiomedical research, and an immunotoxin production laboratory togenerate material for human clinical trials. The Program has access tocentral facilities, including common equipment, and animal rooms.

The first individuals are being recruited for September, 1988. Scien-tists are being sought at the associate or full professor levels to headgroups which will interact to develop new approaches to the biologyand therapy of lymphoid tumors. Their research will include tumorigen-esis, dormancy, effector cells, lymphokines, immunotoxins and geneti-cally engineered reagents. Such individuals should have strong back-grounds in either cell biology, molecular biology, pharmacology ortumor immunology.Individual salaries, research space, and start-up funding are provided.Members of the Program may have academic appointments in basicand/or clinical departments and membership in graduate school pro-grams. Investigators will be able to interact with clinicians at ParklandMemorial Hospital and the soon-to-be-completed University Hospital.Candidates must hold M.D. or Ph.D. degrees (or their equivalents) andmust have a record of major research achievement.Please address inquiries and applications (with Curriculum vitae,references and statements of interests) to:

Dr. Ellen VlteaCancer ImmunoblologyUnhrsIty of Texas Southwestem Medical Center5323 Harry Hines BoulevardDallas, Texas 75235-9048

The University of Texas Southwestem Medical Center at Dallas is anEqual Opportunity/Affirmative Action employer.

ImmunoTherapeutics Inc., a public biotechnologycompany involved in the development of humanimmunopharmaceuticals, has three positions openimmediately.

VICE PRESIDENTFOR RESEARCH & DEVELOPMENT

A senior-level position is open for an individual who willcoordinate and direct research and product develop-ment. Knowledge of GLP and GMP essential. Theindividual will be responsible for patent matters.

IMMUNOLOGISTA senior-level position is open for an individual direct-ly responsible for product research and developmentrelated to monoclonal antibodies, and for the evalua-tion of biological response modifiers in-vivo andin-vitro.

PROTEIN CHEMISTAn organic-protein cheniist position is open for anindividual who holds a Ph.D. and has at least two yearsofexperience. Major areas of responsibility are proteinmodification, protein purification and lipopolysac-charide purification.ITI offers a competitive salary, benefits and a stockincentive/stock option program for these positions.

TM

iI1mmuNoTHERAPEUTICS INC.

Rel wit C.V. or rem md tree referces to Geraldl Vesea, Preudestand Reseach Diector,Iim tincs lac., 35S Riverview Ckde,WM1edMNW50,(701)23-S.

POSITIONS OPEN

ECOLOGIST: Seaver College, the undergraduateliberal arts college of Pepperdine University is seekingapplicants for a -year appointment (assistant professorlevel) in plant or animal ecolgy.Ph.D. is prefcrred, althoudh all-but-dissertation candi-

dates will bc given full consideration. The faculty mem-ber will teach a onc-semester coursc in gcneral ecolgy,general botany or general zoology for majors, and sec-tions of biology for non-majors. Preferencc will bc givcnto applicants who arc cffective teachers, although oppor-utmties exist to supervise undergraduate student researchprojects. Pepperdine is an inde t Christian Univcr-sity under the control of a self-perpetuating Board ofRegents and is related to the Church of Chrst

Applications will be accepted until 15 April 1988, andshould be addre to: Dr. Noman EHhes, NaturalScnce Divis , P dine Unirsity, Malibu, CA90265. Minoriy dm appli are encounged to

ECOLOGIST, ASSISTANT PROFESSOR. One-year sabbatical replacement position for ecologist withbotanical training. Commitment to undergraduate teach-ing and the Ph.D. (or near completion) required. Re-sponsibilities include teaching ecology and field meth-ods, participation in the biology core for majors, team-teaching a general biology course for non-majors, andteam-teaching an interdisciplinary course in populationfood, and poverty. Closing date for receipt of applica-tions is 5 April 1988. Scnd curriculum vitae and threeletters of r ecncc to: Dr. John T. Carlson, Depart-ment of Biology, Pacific Lutheran University (PLU),Tacoma, WA 98447. PLU is an Equal Opprtunity/AffirmativeAction Employer.

ENDOWED PROFESSOR AND HEADBIOLOGY PROGRAMS

THE UNIVERSITY OF TEXASAT DALLAS

Applications are invited for the position of professorand head, Biology Programs, at The University ofTexasat Dallas. The position will be supported by an endowedProfessorship m Biology. The Bidlogy P ms at TheUniversity ofTexas at Dallas, fo a rivate rsearchinstitute, have a long history of and graduateeducation in cell andm l biolgy. The faculty areactively engaged in research in molecular and cell biolo-gy, graduate education at the Ph.D. level, and under-graduate education at the junior and senior levels. Weseek a program head who will provide lcadership andvision commensurate with the rcsearch and educationalgoals ofthe Pograms. The successfil candidate will havemajor input in the hiring ofnew faculty members and inthe renovation of the space of the Biology Programs.Candidates should currently hold a tenure-appointment,have had experience in graduate education m molecularand cell biology or in related areas of biochemistry orbiophysics, and havc a current extramurally supportedresearch program. The position is available from 1January 1989 with a preference to fill the position beforesummer 1989. Applicants should submit curriculumvitae (indation sew a etnicsty for Affima0tiveActionstastlpups is requested but not required) by 15 July1988 to:

Acadeic Search #286The Univcrsity of Texas at Dallas

P.O. Box830688Rchardson TX 75083-0688

The Univity of Tomat at Dalas a an AffirmatiActionlEqual Opportity Employer.EXTENSION POSIHARVEST HORTICUL-

TURIST: The Department ofVegetable Crops and theDivision of Agiculture and Natural Resources, Univer-sity of California, Davis, seek applicants for an academic,11-month, 3-year career-track position. Primary respon-sibility will bc to conduct research and cducation pro-grams on postharvest aspects of transportation and mar-king of fresh horticukural commodities. Candidatesmust have a Ph.D. in horticulture, plant physiology, orrelated arcas. Expcrtmse in postharvest is essential; inplant pathology, marketing, or enginering is desirabk.Send a lettcr of application, curriculum vitae, tranripts,and names and addresses of four rceferencs by 16 May1988 to: Marita Cantwell or Shang Fa Yang D -ment of Vegetble Crops, Unversi of C o ,Davis, CA 95616. Tdephone: 916-752-1410. Referto #A-88-027.AffinmativeActimEqual Opportunity Em-plyr M/FIH.

1444

POSITIONS OPEN

ENVIRONMENTAL TOXICOLOGISTNASA Johnson Space Center invites applications for

an Environmental Toxicologist position. Applicantshould havc academic ramng an/r cxperence in atleast two of the following areas: toxicological risk asscss-ments, environmental health, inhalation toxicology, andanalysis ofgases. Duties will indudecvaluaton oftoxicological hazard potentials ofa variety ofspacecfightecperi-ments and operations, and establishing standards forcontrolling these hazards. Inhalation and other types oftoxicology research opportunities are available. Sendcurriculum vitae with references to: P. J. Cleary, NASAJohnson Space Center, Code AH73, Houston, TX77058. NASA is an Equal Oppotunity Emplyer.

EVOLUTIONARY BIOLOGYDepartment of Biological Sciences ofRutrs Univer-

sity is searching for an ASSISTANT ORASSOCIATEPROFESSOR in cvolutionary biology, particularly ascientist working on evolutionary questions by usmgmodem molecular techniques, with any group of orga-nrsms. Applicants must have demonstrated researchachievement, and develop an active, funded researchprogram, teach, and participate m a large ecology andevolution graduate program within a diverse Depart-ment. Excellent start-up funds and laboratory facilities.Send, preferably by15 April 1988 rdsun, staemnt ofresearch interests, reprints, and names ofthrce refcrencesto: Profssor Steve N. Handel, Chair of EvolutionScarchDrtnent of Biobdcal Sciences, Rut$ers

Unicrl,Zicatwv,NJ 039551059. Ruter ss axEqua Opporuni aieAceiom Employfr.Temple University, Departent of Medicine, Section

of Pulmonary Disease and Critical Care Medicine, seeksto recuit several new FACULTYMEMBERS. Individ-uals with well-defined research interest in the followingareas of investigation are being sought: Physiology andbiochemistryof smooth muscle contraction; structure,function and biological properties ofrespiratory epitheli-al ceDls; neurophannacology of airway tissues. Positionsare available at the assistant, associate professor, andprofessor rank. Send r6sum6s to: Dr. S.cKels ChieSection of Pulmonary Disease and Critcl CareMedicine, Temple Univerit Healh Sciences Center,931 Parkinson Pavilion, Broad and Tioga Streets,Philadephia, PA 19140.

FACULTY POSITIONSMOLECULAR AND CELL BIOLOGY

PENN STATEApplications are invited for faculty positions at any

rank mn the Department of Molecular and Cell Biology.We seek exceptional candidates whose research interestsencornpass any area of molecular and cell biology butspecial consideration will be given to those whose re-search complemcnts our areas of strength and futureinterest including (i) prokaryotic molecular genetics,regulation, development, and pathogenesis; (ii) struc-re/futin of proteins, and m e interac-

tions; and (iii) eukaryotic cell proliferation, differentia-tion, interactions, immune mechanisms, and regulation

of anidte ae xpctdto have exceptional researcharedentials and a commitment to teaching at the graduateand undergraduate levels in onc or more of the disci-plines represented by the Department. The Departmentis contemporary and vigorous and is responsible forresearch and teaching programs in biodeistry, micro-biology and mokcular ancrcel biology. The Departmenthas 30 research faculty and 80 graduate students. Wemaintain an aggressive research enviromnent and cncour-age cooperative and intcrdisciplinary projects within andoutside ofthe Department. Strong interactions existwiththe Chemistry Dcpartment, the College of Agicukurc,and the ncwly cstablshed Biotechnology Insttute withwhich joint appointments may be possible. Applicationswill be reviewed starting 1 May 1988 and contnue untilthe positions are filled. Candidates should submit ar6sunn incuding a statement of research interests andgoals, copies of no more than three recent publicationsand the names, addresses, and telephone numbers of atleast threercferencs to: Dr. Robert W. Bernlohr,Chairman of the Search Committee, Dertment ofMokcular and Ceil Biology, 108G ouse Labora-tory, The Pennsylvania State University, UniversityPark, PA 16802.

The University isanAfmi eAction/Equa 0 ni-tyEmplVyer. Women ax#dmiote c ln to apply.

POSITIONS OPEN

FACULTY POSMONCOLUMBIA UNIVERSITY

DEPARTMENT OF ANATOMY ANDCELL BIOLOGY

The Departnent of Anatomy and Cell Biology seeksapplicants for a tenure-track faculty position for a candi-atc with background and teaching cxperience in gross

human anatomy, who is interested in participating in thedevelopment of computer-assisted instruction and iscapabl of establishing an independent research programin cell biology, cellular neurobiology, or a related area.Please send curriculum vitae, statement ofresearch goals,and the names of three professional references to: Dr.Michael D. Gershon, MD., Chairman, DepartmentofAnatomy and Cell Biology, Columbia University,Collge of Physicians and Surgeons, 630 Wcst 168Street, New York, NY 10032. lmbi Uni stanAffirmativeAct-ion/Equal Opportunity Emlyr

FACULTY POSMON INMOLECULAR PHYSIOLOGY/BIOLOGY

The Department of Physiology at the Medical Collegcof Wisconsin is seeking an investigator at the assistant/associate professor level for a tenure-track position in thearea ofmolecular genetics. Applicants will be expected todevelop a research program in an area related to cardio-vascular and/or renal physiolo y, and interact with cellu-lar and integrative physiolksts in a collaborative re-search program investigating arterial blood pressure reg-ulation. Candidates experienced in molecular technicuesfor studying membrane function, contractile protems,hormone synthesis, and endothelial or vascular musclecell growth are especially desired. Teaching responsibil-ities icude participation in graduate and mcdical schoolcourscs. The Department of Physiology offers a coopera-tivc scientific cnvironment and is located in a modemfacility. A new building connected to the Deparmnent ofPhysiology is presently being constructed, which willhouse an interdepartmental molecular biology affinitygroup with varied research interests. Applicants shouldsend curriculum vitae, a statement of career objectives,and the names ofthree references to: A. W. Cowle, Jr.,Ph.D., Professor and Chairman, Departent ofPhysiology, Medical College ofWisconsi, 8701 Wa-terown Plak Road, Milwaukee, WVI 53226.An Equa Opportunity Emplyer.

FACULTY POSMON-GENETICIST: Ph.D.,must maintain active research, supervise M.S. students,consult and collaborate with biology faculty and thecommunity. Demonstrated record of research productiv-ity in cellular/organismal genetics as shown by publica-tions and funding. Excellent teachirg is required m threeto four assigned genetics courses andin a g-ncral biologyclss. Position is in a vigorous department of 16 facultyon an 8000-student university located at Cheney andSpokane, a region that offers a high quality of life.Renewabk 1-year term appointment at assistant profes-sor level to start September 1988. Send curriculum vitae,statement ofresearch interests and three lettcrs ofrecom-mendation to: Genetic Search Committee, Depart-mn t of Biolgy-MS #72, Eastem WasingtnUnivrty, Cheney,WA 99004-9989. Equal Op -nty EmplyerAffirmative Actson.

The Center for Molecular Biology invites applicationsfor three tenure-track FACULTY POSITIONS forsummer 1988 to early 1989 hire date, at the level ofassistant, associate, or full professor. Tenure will be in anappropriate department. Multiple research-track facultypositions at the level of assistant, associate, or fullprofessor (research) are availabk with the same hiredates. Gcnerous start-up funds are available. These posi-tions are a part of a major University-wide expansion inmolecular biology. The focus of the Center is on health-related research. Candidates with a Ph.D. or M.D.degrce, postdoctoral cxperience, and demonstrated re-search excelence in an appropriate area of molecularbiology will be considered. Send applications (deadline:1 June 1988) including curriculum vitae, the names of ateast three references, and a statement offuture researchplans to:

Orlando J. Miller, DirectorCenter for Molecular Bioogy

Wayne State University540 East Canfield

Room 1201 Scott HallDtroit MI 48201

SCIENCE, VOL. 239

POSITIONS OPEN

FACULTY POSMON INNEUROSCIENCES

The Dc rtment of Veterinary Biosciences has a ten-ure-track faculty position opening in the area ofneurobi-ology. All candidates with research expertise in a modemneuroscience area will be consideZ4 t preference willbc given to physiolos/anatomists studying problemsat the cellular and molecular levels. The candidate will beexpected to devdop an independent active research pro-gram as well as teach in the College's professional andgraduate programs. Candidates with active independentrcsearch progams will be considered for semor levdfaculty appomtments. Applicants should have a Ph.D.degree together with postdoctoral expenence. Deadlinefor applications is 8 April 1988 or unil position is filled.Submit curriculum vitae, deoription of research inter-ests, and letters from three references to: Dr. HaraMisra, Head, De t of Veterinary Bi ces,Virnia-Maryland Reonal Colkcge of VeterinaryVicine-Maryland TecV, B acks VA 24061.Vrgna T~c isan Equal OpporteunityLffirtwati Ac-

tion Emploer.

WEST VIRGINIA UNIVERS1IYFACULTY POSMONS IN

PHARMACOLOGY/TOXICOLOGYWest Virginia University invites applications for two

tenure-track positions at the assistant professor leve.Applicants should have a doctoral degree in pharmacolo-gy, toxicology or related discipline and postdoctoralresearch experience. Rescarch accomplishments and evi-dence of ability to develop independent, extmally fund-ed research wiJl be prime considerations in the selectionprocess. The positions will begin on or about 1 JulyT1988. Applicants should submit curriculum vitae, indud-ng comp~lete bibliography, and request three letrs ofreerence be sent to: Dr. Robert E. Stitzl at theDepartment of Pbarmacky and Toicology, WestVnia Unim"scsy M a Center, Morgantown,W526506 by 1 April 1988.TOXICOLOGIST: Prefcrence will be given to appli-

cants whose research expertise focuses on the celfular,biochemical and/or molecular events of toxicity. Teach-ing responsibilities require a broad knowledge oftoxicol-ogy.PHARMACOLOGIST: Prefercnce will be given to

those applicants whose research expertise focuscs on thecelular, biochemical and/or molecular aspects ofpharma-cology. Teaching responsibilitics requirc a broad knowl-edge of pharmacology.

West Virginia Univenity is an Affirmative ActionlEqualOpportnity Empkyer.

TWO FACULTY POSMONS IN FOOD SCI-ENCE AND NUTRMON. Assistant Professor/Asso-ciate Professor, Dcpartment of Food Science and Nutri-tion, University ofMinnesota, St. PauL Tenurc-track ortenured. Must havc Ph.D. in nutrition, or related ficld.Apply by 10 May 1988 to: Dennis A. Savaiano, Chair,Search Committee, Department ofFood Science andNutrition, University ofMinota, 1334 Eckles Av-enue, St. Paul, MN 55108. Tdelphone: 612-624-6232. Application indudes curriculum vitae and namesand addresses of at least three references. Start on orbefore 1 September 1988.The Universt ofMinnesota is an Equal Opportuniy

Educator and Emlyer and pecicalUy invite and enour-ages women and minoritie.

HEAD

DEPARTMENT OF ANIMAL SCIENCE

The Collegc ofAgriculture and Life Sciences ofNorthCarolina State University is searching for an outstandingindividual to adminiser the teaching, research and exten-sion pograms of the Department of Animal Science.Candidates for the position should havc a Ph.D., and ancellent professional reputation in an animal science or

related field. Administrative experience or demonstratedleadership potential in academic affairs, rmsearch, andexension is preferred. Write for a complete job descrip-tion or appy by sending a lettr cxplaining mterest,qualifications, r .sune and euest three letters of refer-ence by 1S May 1988, to: Dr. B. E. Caldweil, Chair-man, earch Committee: Box 7620, North CarolinaState University, Raleih, NC 27695-7620. NorthCAlina State Univen*i ts an Equa Oppirtnty/Affirna-ieAaion Employer.

I8 MARCH 1988

R.P. Scherer Corporation is an interna-tional developer of drug formulations anddelivery systems and the world's largestproducer of softgels (soft gelatin capsules)for the pharmaceutical and nutritional sup-plements industries. The firm also pro-vides other diversified health care pro-ducts and services.R.P. Scherer has established a new phar-maceutical research and developmentcenter in Ann Arbor, Michigan. Ann Arboroffers an exceptional quality of life in-cluding a wide variety of sophisticatedcultural and educational environmentswith a seemingly affordable high standardof living.Positions are available for staff with ex-perience at all levels of education to workin new and exciting areas of drug deliveryresearch:* Development Pharmacists

(Ph.D.)-Responsible for design anddevelopment of unique drug deliverysystems. 1-5 years experience.

* Development Pharmacists (M.Sc.,B.Sc.)-Laboratory experience in for-mulation and development. 1-5 yearsexperience.

If you would like to join a new and excitingresearch enterprise, please send yourresume for consideration to:

R.P. Scherer CorporationPersonnel Manager, Dept. SM318P.O. Box 6070 * Troy, Ml 48007Equal Opportunity Employer M/F/HN

a*Rp

National Institutes of HealthU.S. Public Health ServiceNATIONAL INSTITUTE OFNEUROLOGICAL ANDCOMMUNICATIVE

DISORDERS AND STROKEStaff/Senior Staff

FellowshipThe Surgical Neurology Branch (SNB),Division of Intramural Research (DIR),National Institute of Neurological andCommunicative Disorders and Stroke(NINCDS), National Institutes ofHealth (NIH), Public Health Service(PHS), announces a Staff Fellowshipopening. This postdoctoral tenure-track fellowship is available to studythe cell biology, endocrinology ormolecular biology of the pituitarygland and pituitary tumors. The ap-pointee will be expected to initiate in-dependent research. SNB seeks ascientist who can relate laboratory ef-forts to clinical pituitary problems andwho is eager to interact with an activepituiatry surgery program.

For the NIH Staff Fellowship Program,candidates must be U.S. citizens orresident aliens within four (4) years ofreceiving U.S. citizenship, and musteither have been awarded their doc-toral degree in fields closely related tothe position, or have been certified by auniversity as meeting all the re-quirements leading to such a doc-torate. Candidates with less than 3years of professional level post-doctoral research experience may beconsidered for entrance into the pro-gram as Staff Fellows (SF). SeniorStaff Fellowships (SSF) may be con-sidered for those having 3 to 7 years ofprofessional level post-doctoralresearch experience. The salary rangesfor the SF Program are $20,000pa(PhD's)/$24,688pa (MD's) to $35,491pa(PhD's)/$37,997pa (MD's). The salaryranges for the SSF Program are$24,000pa (PhD's)/$28,000pa (MD's) to$42,600pa (PhD's)/$49,266pa (MD's).Starting salary is commensurate withexperience. The initial appointment isfor two (2) years with additional exten-sions of up to five (5) years possible,for a total of seven (7) years in the pro-gram.

Further position information andqualifications requirements may be ob-tained by calling Clifford Schein on(301) 496-6334. The position is locatedin Bethesda, Maryland. Interested can-didates should send a curriculumvitae, a brief statement of research in-terests and the names of three (3)references to:

Dr. Edward H. OldfieldChief, Surgical Neurology Branch

DIR, NINCDSBuilding 10, Room 5D37National Institutes of Health9000 Rockville PikeBethesda, MD 20892Telephone: (301) 496-5728

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

Assistant orAssociateScientist

Applications are sought to fill twotenure-track positions in the Depart-ment of Chemistry at the Assistantor Associate Scientist level. Theopenings are in the general areas ofisotope chemistry (stable and/orradioisotopes) and in ary area oforganic biogeochemistry. Applicantsshould have a PhD, preferably post-doctoral experience, and a strongbackground in basic physical, organicor analytical chemistryas applied tothe study of chemical rates andprocesses in marine systems. Pleasesend a letter of inquiry and curri-culum vitae including a statement ofresearch interest to:Chairman, Chemistvy Department

P.O. Box 54P

0~

00

WOODS HOLEOCEANOGRAPHIC

INSTITUTIONWoods Hole, MA 02543

An equal opportunity employerM/F/H/V

r

L

POSITIONS OPEN

FACULTY POSMON-Department of AvianMedicine, the University of Georgia. Basic researchposition requiring Ph.D. degree, responsibility for grad-uatc student training. Biotechnology skills and postdoc-toral trainiing or equivalent desirable. Rank and salaryopen. Receipt of applications deadline is 1 May 1988.Inquiries should be directed to: Dr. Oscar J. Fletcher,Head, Avian Medicine, 953 College Station Road,Athens, GA 30605. An Equal Opportunity/AffirmativeAction Institution.

FELLOW-at the University of Cincinnati. To studythe genetic regulation of globin synthesis, especially inreference to the fetal hemoglobin switch. Research activi-ties will entail coning DNA from putative rcgulatoryregions ofhuman genes, and studying their expression inappronsit expression vectors. Ideally, candidatesshuld have prior training in molecular genetics. Forapplicants with the M.D. the fellowship can be struc-tured around either medical genetics or hematolgy.Send curriculum vitae to: Donald L Ruckgel,

M.D., Ph.D., Comprehensive Sickle Cel CenterChildren's Hospital Medical Center, Elland and Be-thesda Avenues, Cincnnati OH 45229.

An Equal Opportunity Employer

HUMAN GENETICSThe Wadsworth Center invites applications for two

tenure-track STAFF SCIENTIST positions equivalentin rank to an assistant professor. Both positions requirethe applicants to possess a Ph.D. or M.D., have postdoc-toral experience, and have an interest in molecular genet-ics applied to the human genome.

Position 1: Candidates are sought who are applyingmodem experimental approaches to the study of thehuman genome. They will be expected to carry out avigorous independent program in basic human geneticresearch.

Position 2: Candidates are sought whose particularinterests are the application of probe technologies tocytogenetic rearrangements, human genome probe li-branes, genetics diagnostic probe techniques, and thedevelopment of quality assurance programs for probetechnology with opportunities to pursue human geneticresearch.The Wadsworth Center is a research-oriented institu-

tion with a staff of over 150 scientists. It offers a uniqueopportunity to engage in state-of-the-art research pro-grams which have impact on public health. Both posi-tions can include participation in the new SUNY PublicHealth Sciences graduate school program. Send curricu-lum vitae to: Dr. Lorraine Flaherty, Laboratory ofImmunology or Dr. Ann W0ile,laboratory of Hu-man Geneics, Wadsworth Center for Laboratoriesand Resea, P.O. Box 509, Albany, NY 12201.

INDUSTRIAL POSITIONSH. T. McCormick Associates, Inc., a nationally recog-

nized executive search firm, has exclusive openings forthe following positions: ASSOCIATE MEDICAL DI-RECTOR: Drug Regulatory Affairs M.D./Ph.D. re-quired. ASSOCIATE MEDICAL DIRECTOR: In-ternal Medicine. ASSOCIATE MEDICAL DIREC-TOR: Infectious Diseases. Board-certified M.D. AS-SISTANT CLINICAL RESEARCH DIRECTOR:M.D. with research/fellowship training in cardiovascularmedicine. Six figure compensation. DIRECTOR OFIMMUNOLOGY: Monoclonal antibody production.DIRECTOR OF IMMUNOASSAY DEVELOP-MENT: Ph.D. Immunology. Some industrial expen-ence. To $70,000. PRINCIPAL RESEARCH SCI-ENTIST: Tumor biologist to develop new in vivohuman and murine tumor models. Expenence in use ofathymic nudc mice for propagation of human tumors.SENIOR RESEARCH SCIENTISTS: infectious dis-ease, cardiovascular and atherosclerosis assays. Ph.D. inimmunology, pharmacology, biology. Some industrialcxperience. To $65,000. SENIORRESEARCH SCI-ENTIST: Ph.D. biochemist for blood platelet develop-ment. To mid-$50,000. CLINICAL RESEARCHAUDITORS: To mid-$40,000. Submit curriculum vitaein confidence to: Ann F. Lees, Director of ScientificRecruitmcnt, H. T. McCormick Associates, Inc., P.O.Box 1206 Princeton, NJ 08540; or 3086 Route 27,Suite #5, Kendall Park, NJ 08824; or facsimilenumber: 201-297-7391.

CHEMICAL EDUCATION FOR PUBLICUNDERSTANDING PROGRAM (CEPUP)Salary range: $31,800 to $52,000 annual. The project

is seeking two INSTRUCTIONAL DEVELOPERSto develop instructional materials to work in classroomsand with public groups. Qualifications: M.S. or Ph.D.degree in sciences or science education, experience work-ing with teachers, developing instructional materials and/or related experience. Strong academic background inchemistry and/or physics required. Submit resume, appli-cation letter describing qualifications, and names andaddresses of three professional references to: CEPUP,Lawrence Hall of Science, University of California,Berkeley, CA 94720. Application deadline: 15 April1988. Anticipatcd starting date: 1 July 1988, or byagreement. The Unierity ofCa4fomia is an Equal Oppor-tunitylAffirmativeAction Employer.

INSTRUCTOR OR VISrIING ASSISTANTPROFESSOR in ecology/evolution or cell biology/genetics for 1-year appointment with possible renewal,to begin 1 September 1988. Major teaching responsibil-ities in large introductory biology course (ecology, cell ororganismic biology) and possibly an appropriate ad-vanced course. Preference for candidates with strongteaching credentials. Ph.D. required for assistant profes-sor, masteres degree for instructor level. Salary commen-surate with rank and experience. Send resum, tran-scripts, and three letters of recommendation by 4 April1988 to: Dr. Timothy S. Wood, Visiting FacultySearch Committee, Department of Biolnuical Sci-ences, Wright State Umversity, Dayton, OA45435.W*kgt State Univerity is an Equal OpportunitylAffir-

mativeAction Employer.

LABORATORY DIRECTOR/RESEARCH AS-SISTANT PROFESSOR sought for Blood Vessel Re-search Group. Responsibilities include: administration oflaboratory activity, supervision of research in vascularpharmacology, conduction of independent research andteaching of graduate and undergraduate students. Thecandidate is required to have a Ph.D. in vascular pharma-cology. This position is nontenure track and the candi-date is expected to compete for external funding. Appli-cants must send letter of application, curriculum vitae,and four letters of reference by 1 April 1988 to: John A.Bevan, M.D., Department of Pharmacolony, CollcegofMedicine, University ofVermont, Burlington, VT05405. The Univensy ofVermont is an Equal Opportuni-ty/AffirmativeAction Employer. Women and minoritis are

encouraged to apply.

MEDICAL MICROBIOLOGYFACULTY POSITION

Applicants are invited for a tenure-track position at theassistant/associate professor level. Previous teachingexperience in pathogenic bacteriology and demonstratedpotential for independent research are desirable. Respon-sibilities include teaching medical, podiatric, and physi-cian assistant students. Research interests are open, andlimited institutional funds are available. Rank and salaryare dependent on qualifications and experience. Sendcurriculum vitae, and names of three references to:William J. Dyche, Ph.D., Associate Dean for Pre-Clinical Affairs, University of Osteopathic Medicineand Health Sciences, 3200 Grand Avenue, DesMoines, IA 50312. An Equal Opportunity Employer.

MANAGERCHILDHOOD AMPUTEE CENTER

Mary Free Bed Hospital and Rehabilitation Center hasan immediate opening for the Manager of SpecialityRehabilitation program servicing children with limbdeficiencies. Responsible for directing multi-disciplinaryprograms, developing/coordinating research activities.Opportunity for academic affiliation. Master's degree inhealth care specialty required, research experience/addi-tional research training preferred. Send resume indudingsalary history to:

Medical DirectorMary Free Bed Hospital and

Rehabilitation Cecnter235 Wealthy SE

Grand Rapids, MI 49503Equal Opportunity Emtloyer

MARINE BACTERIOLOGISTThe Department of Oceanography at Texas A&M

University in College Station, Texas, is seeking a marinebacteriologist for a tenure-track position at the assistantor associate professor level, beginning 1 September1988. Emphasis will be placed on potential contnbutionsthat the candidate can make to ongoing interdisciplinaryefforts in the areas of sediment and water column biologyand chemistry. Present studies emphasize organic matter

clin and nutrient regeneration. Salary and rank aredependent on qualifications. The Department of Ocean-ography is in the College of Geosciences and indudes 30full-time faculty in disciplines of biology, chemistry,physics, and the earth sciences; the Geochemical andEnvironmental Research Group; a MultidisciplinaryModeling Group, the international office ofWOCE, andan Ecosystems Research Group. Facilities indude anROV and the 182-foot RN Gyre. The Texas A&MUniversity System indudes the Texas Sea Grant Pro-gram, the headquarters of the Ocean Drilling Program,and research facifities with a runng seawater system inGalveston. Please send letters of inquiry, resume, state-ments of research and teaching interests, reprints, andnames of three references to: Dr. Eric Powell, Depart-ment of Oceanography, College Station, TX 77843.Deadline for recipt of application material follows thedate of this issue by 4 weeks. Texas Ati'M iS an EqualOpporunity Emplyer.

MEDICAL INSTRUMENTATION DESIGNENGINEER, 40 hours per week, 8:00 a.m. to 4:00p.m., $30,780 per year. Will design, develop, and imple-mcnt measurement transducers for controlled biologicaland physical measurement devices using optical, thermaland magnetic sensors. C-language and assembly pro-gramning languages are used for optimizing simulationof experimental data and for microprocessor interfacedriver dcsign and development. Utilization ofanalog anddigital circuits for sensonng, displaying and instrumentdesign. Master of science degree in physics, and 6months of experience as a medical instrumentation de-sign engineer or 6 months of experience as a systemsprogrammer required. Experience must indude workwith analog and digital circuitry or applicant must have abachelor of science degree in electncal engineering. Sixmonths of pnor expenence must include the use of C-language and assembly programming languages. Sendresumes to: Illinois Department of Employment Se-cuity, 401 South State Street-3 South, Chicago, IL60605. Attention: L. Donegan, Reference #7831-L.An employer paid ad.

MOLECULAR GENETICISTNathan S. Kline Institute, Orangeburg, New York, is

seeking to fill a research scientist position immediately. APh.D. in biochemistry or molecular biology is requiredfor projects involving the molecular bases and biochemi-cal regulations of genetic differences in brain neuraltransmission. Applicants should have a good backgroundin recombinant DNA techniques, and experience withpreparations and analysis ofmammalian DNA, construc-tion and screening DNA libraries, vector construction,Southem blotting, RFLP analysis and enzyme assays.Salary commensuratc with experience. We are located inOrangeburg, 20 minutes from New York City. Submitcurriculum vitae, list of publications, recent reprints, andthree letters of recommendation to: Dr. Csaba Vadasz,Laboratoq of Neurobehavioral Genetics, Nathan S.Kline Institute, Orangeburg, NY 10962.

SCIENCE, VOL. 239

Boston Biomedical Research Institute (BBRI)invites inquiries from INVESTIGATORS whowould like to work in central Boston in a private,non-profit, basic research organization with ex-cellent facilities, where achievement in research isthe major commitment. The successful candi-dates will be expected to obtain grant support.The Institute would especially like to expand itsresearch in cell biology, immunology, and neu-robiology, but applications from innovative in-vestigators in other biomedical fields would alsobe welcomcd. There is no deadline for applica-tion. A resume and a briefdescription ofresearchinterests should be addressed to: The ExecutiveDirector, Boston Biomedical Research Insti-tute, 20 Staniford Street, Boston,MA 02114.BBRI is an Equal Opportunity Employer.

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POSITIONS OPEN POSITIONS OPEN

FACULTY AND POSTD RALPOSITIONS AT THE DENTALRESEARCH CENTER, UNIVERSITYOF MEDICINE AND DENTISTRYOF NEW JERSEY-NEW JERSEYDENTAL SCHOOL.

Applications are invited for positions at thenewly-established Reseah Center. SeeldngD.D.S, Ph.DorM.D. indMdualswithinterestand experence in the area of chemistry andfunction of salivary and gastrointestinalsecretions. Preference will be given tomolecular biologists, biochemists, im-munologists, or physiologists pursuingresearch in gIVoprotein snthss and pro-cessing, biochemical pharmacology, en-zymology, lipid and protein metabolism,connective tissue and bone mineraliation,membrane receptors and signal transduc-tion, and immune and nonimmune mehn -

sm in the healfth ofthe oral cavity. Excetsalary/benefits. Send resurne, statementofinterests, and references, to: Dr. B.L.Slomiany, Director, DentalResearch Center, UMDNJ-NewJersey Dental School, (S), 110BA eSt, -NewNow07103-2425.

The UMDNJ is an Affirmafive kction/R EalN JpW ERSEY WF/HN.

N E W I E R S E Y_

COLUMBIA UNIVERSITYVice Provost for

Research & Technology DevelopmentColumbia University invites applicationsfor the position of Vice Provost for Re-search and Technology Development.The Vice Provost reports to the Provostof the University and works closelywith the Vice President for Arts andSciences and the Vice President forHealth Sciences. The Directors of theOffices of Science and Technology De-velopment and Projects and Grantsreport to the Vice Provost.

The Vice Provost will:-provide leadership to the University inthe planning, development and admin-istration of reseach activities supportedby government, foundations, andindustry;-facilitate collaboration between theUniversity and private industry, partic-

ularly in the health sciences. the basicand applied sciences, and engineering;Qualifications: Earned doctorate in sci-ence, medicine, or engineering, with arecord of distinguished research expe-rience and significant experience in anacademic, governmental, or industrialsetting. Candidates should possess anappreciation of university process anda demonstrated ability to develop andimplement new programs.Send curriculum vitae with letter of ap-plication including salary history beforeApril 3, 1988 to:Auerbach AssociatesBox 2681Cambridge, MA 02238Columbia University is an AffirmativeAction, Equal Opportunity Employer.

CHEMIST,MEDICINAL OR FORMULATIONThe Aquired Immunodeficiency Syndrome(AIDS) Program of the National Institute ofAllergy and Infectious Diseases (NIAID) ofthe National Institutes of Health is seeking aMedicinal Chemist or Formulation Chemistto join the Drug Development and Applica-tions Section of the DevelopmentalTherapeutics Branch. The Branch is respon-sible for planning and directing a federal pro-gram of extramural research projects for thediscovery and preclinical development ofpotential therapies for the treatment of AIDSand its associated opportunistic infections.Major efforts presently underway or plannedin the Section include dose ranging studiesof experimental drugs in retrovirus-infectedanimals, pharmacokinetics of new agents innormal and diseased animals, preclinicaltoxicity studies of potential drugs, informa-tion exchange and planning of new ini-tiatives. A Ph.D. or D.Pharm. in medicinalchemistry, formulation chemistry or relateddiscipline is desired but not essential. Rele-vant experience in clinical drug formulation,drug synthesis, production scale-up andanalytical chemistry may be considered asimportant as specific degree training. Salaryrange is $39,501 - $60,683 per annum.

U.S. citizenship is required. Send curriculumvitae, bibliography and names of referencesto Dr. Charles L. Litterst, NIAID/AIDS Pro-gram, Room 244p, 6003 Executive Boulevard,Bethesda, Maryland 20892.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

POSITIONS OPEN

MICROBIOLOGISTTenure-track position, assistant professor level, begin-

ning August 1988; to teach undergraduate courses inmicrobiology, related areas (immunology or parasitolo-gy), and/or in general biology. Conduct research work-ing with students. Ph.D., bilingual candidate (Spanish/English). Submit curriculum vitae, statement of teachingand research interests, and three letters of recommenda-tion by 25 April 1988 to: Dr. Ansa L. Acevedo, Chair-person, Biology Department, University of PuertoRico (UPR), Cayey, Puerto Rico 00633. UPR is anEqual Opportunity/AffirativeAction Employr.

MOLECULAR BIOLOGISTA tenure-track position for an assistant professor with

demonstrated experience in DNA repair mechanisms isanticipated for fall 1988 in the Department of BiologicalSciences, Northemn Illinois University. A Ph.D. andpostdoctoral experience are required. The successful can-didate will be expected to develop a vigorous, extemallyfunded research program and direct graduate (M.S. andPh.D.) students. Preference will be given to individualsexperienced with prokaryotic or lower eukaryotic DNArepair mechanisms and able to contribute to the radiationbiology program. Teaching obligations will involve theequivalent of one course per semester, occasionally in-duding introductory biology courses. Northern IllinoisUniversity's proximity to Chicago also allows collabora-tive research with institutions such as Argonne NationalLaboratory.Send curriculum vitae, statement of research goals,

three most significant publications, and three letters ofreference by 30 April 1988 to: Dr. Marvin J. Starzyk,Chairman, Department of Biological SaewesNorthern Illinois University, DeKaIb, IL 60115-2861. Telephone: 815-753-1753. The Univerity is anAffirmativeAction/Equal Opportunity Employer.

MOLECULAR BIOLOGYApplications are invited for one and possibly two

TENTURE-TRACK POSMONS from persons withstrong backrounds in recombinant DNA technology,postdoctora[ research experience and publications mmolecular and/or cellular biology. One position will be atthe assistant or associate protessor rank, and the otherwill be open to all ranks. The positions will complementexisting research programs in molecular and cellularbiology. The appomtees will be required to maintain anactive research program and to teach courses in eithergenetics, microbiology, cell biology or biochemistry. Theposition will begin 15 August 1988, and the salary andrank will be commensurate with experience.The faculty of the Department of Biological Sciences is

strongly committed to research and to their responsibil-ities to offer both undergraduate and graduate programs.Oakland is a state-supported university on a 1,400-acrecampus 25 miles north of Detroit.

Applicants should submit curriculum vitae, a briefdescnption of their research plans, and have three refer-es send letters of recommendation before 1 April 1988to:Dr. F. M. Butterworth, Chair Search Committee

Department of Biological SciencesOakland University

Rochester, MI 48309AffirmativeActionEqual Oppotunity Employer

NMR SPECTROSCOPISTCandidate must have a Ph.D. in Biochemistry and a

minimum of 5 years of experience in the practicalapplication of NMR spectroscopy to the elucidation ofprotein structure. Knowledge of all 2D techniques isessential and preference i1 be given to those withpostdoctoral experience (preferably in the pharnaceuti-cal industry) and who are experienced in protein isola-tion and purification. Experience in computer graphictechniques is also highly desirable.The starting date is 1 June 1988 (or earlier, if re-

quired), with a yearly salary in the range of $30,000 to$35,000 depending on expenence.

Applicants should send curriculum vitae induding afull description of experience, relevant reprints, and thenames of three referees to: Dr. Neil MacKenzie, De-partment of Pharmaceutical Sciences, University ofArizona, Tucson, AZ 85721. Telephone: 602-626-4898. Closing date for applicants is April 1988.

The Univmity ofArzona is anAffirmativeAction/EqualOpportunity Empoer.

MEDICAL (Ph.D.) CYTOGENETICIST. TheCalifornia Prenatal Diagnosis Institute SPDI in San Jose,California, has a fill-timc position available for an experi-cnced Ph.D. cytogenetcist (AMBG-cligible or certifiedwith a minimum of 4 years of expericnce) at a cytogenet-iCS prenatal diagnosis laboratory program. Suc-essfulcandidates should be professioned in amniotic cell, tis-sue, and blood cultures, photomicroscopic and darkroomskills, banded chromosome identification and karyotyp-ing. Salary is commensurate with experience and compet-itive with San Francisco Bay area laboratories. Sendr6sumr to: CPDI, Post Office Box 9249, number 104,San Jose, CA 95157.

MOLECULAR VIROLOGIST-BIOCHEMIST.The Institute fur Moleculr Virology and the Depart-ment of Biochemistry, University of%sconsin-Madisonseek applicants for a joint tenure-track, professorial ap-pointment in the area of the molecular biology andbiochetmi of viruses. Appointments will be consid-ered at any level, but applicants in an expansion phase intheir career will be given preference. Applicants musthave an outstanding record of achievement m research invirology and biochemistry. They must have a researchprogam suitble for training and supporting postdoctor-al fellowsand graduate students. They must have interestin and demonstrable aptitude for providing instructionto students in bioch niisty. The deadline or receipt ofapplications is 20 April 1988. Applicants should requeststandard application furms or, alternatively, should sub-mit vitae, a narrative descnrption of their scientific inter-ests and achievements, and the names of four referees.Wc especially welcome application by women and byminonties. The University of Wisconsin is an AffirmativeAction/Equal Opporunity Empyer.

Application forms may be obtained from and materialsshould be sent to:

Paul Kaesberg, ChairmanInstitute fr Mo[ecular Virology

1525 linden DriveUniversity ofWimsconsinMadison, WI 53706

608-262-2205

NUTRIMONTWO TENURE-TRACK POSMONS available in

Department of Home Economics, July, 1988. Appoin-tees will be expected to establish strong research programin clinical, community, or expeimnental nutntion provid-ing opportunities for training graduate students. Candi-dates should have ability to attract external funding anddevelop national recognition as scholar. Undergraduateand graduatc teaching in nutrition and dietetics. Oneposition will direc AA Plan IV/V program. Ph.D. innutrition required, RD and postdoctoral experience pre-ferrcd. Closmg date: 1 April 1988 or until suitablecandidates are found. Send curriculum vitae, three lettersof reference, transcripts, and statement of teaching andresearch interests to:

Dr. Adria RL Sherman, ChairDepartment of Home Economics

Rultgers UniversityDavio Hall, Cook CollegeNcw Bru ick, NJ 08903Telephone: 201-932-9516

An Equal Oppotunity/Affim ie Action Employer.PALEOZOIC INVERTEBRATEMACROPALEONTOLOGIST

U.S. Geological Survey, Branch of Paleontology andStratigraphy, announces vacancy for invertebrate macro-paleontologist to study lower and/or middle Paleozoicrocks. Prefer applicants with Ph.D.; must be U.S. citizen.Prefer experienced, field-onented researcher specializinin established biostratigraphically useful fossil group(s).Salary and grade negotiable based on career expenence(salary range $33,218 to $60,683 per annum, GS-12 toGS-14). Duty station will be deternined at time ofseection.Scnd application to: A. G. Harris, U.S. Geological

Survey, U.S. National Museum, E-501, Washington,DC 20560. Teekphone: 202-343-3495 by 15 April1988; must indude Standard Form 171 (Personal Quali-fications Statement) available from above address or anyFederal personnel office and complete list of publica-tions.

The U.S. Geolgical Survey is an Eqal OpportunityEmployer.

PHARMACOLOGIST. Applications are invited fora tenure-track faculty position in the Departnent ofPharmacology, University of South Carolina School ofMedicine. Ph.D. and/or M.D. degree and postdoctoralexperience required. The successful candidate will beexpected to develop an independent research programwhich merits extramural support and to teach medical/graduate students. Individuals should submit curriculumvitae, statement of professional goals, and the names ofthree references to: Dr. D. 0. Allen Chairman,nD-prtinent ofPharmacokogy, University ofSouth Car-olina School of Medicine, Columbia, SC 29208. TheUnierity of South Carolina is an Equal OpportuntylAffirmatieAction Employer.

PHYSIOLOGIST: The Cerebrovascular ResearchCenter Department ofNeurology is seeking applicationsfor a full-time research position at the level of assistant orassociate research professor. The applicant must havc hadextensive laboratory experience in research on the cere-bral circulation with a proven record of research accom-plishments. Candidates should have a strong interest incercbrovascular disease. Applicants should send curricu-lum vitae, a description of research interests, and threektters ofreference to: Dr. Martin Reivich, Cerebrovas-cular Resarch Ccnter, 429 Johnson Pavilion, Uni-verst of Pennsylvania, Philadelphia, PA 19104-6063. The Unieity of Pennsylama is an AffirmatieAcinEqul Oppounity Emloyer.PLANT BIOCHEMIST: Department ofBiochemis-

try, University of Nebraska-Lincoln. A 12-month ten-ure-track position with 80% research and 20% teachingat the assistant or associate professor level. Will beexpected to develop a plant rsearch ro m that relieson modem biochemical and molecular iological tech-niques. A Ph.D. in biochemistry, or dosely reted area,and postdoctoral experience are required.Submit curric-ulum vitae, statement of research interests and plans,representative reprints, and three letters of reference by 2May 1988 (or until suitable applicant is found thereafter)to: Dr. Robert Klucas, Dcpartment of Biochemistry206 Biochemistry Hall, University ofNebraska-Lin-coln, Lincoln, NE 68583-0718. Telephone: 402-472-2932.

AffirmativeAction/Equal Opportunity Employer

PLANT GENETICSISOYBEAN. Applications areinvited for a tenure-track ASSISTANT PROFESSORposition (80% research, 20% teaching). A Ph.D. degreein plant genetics or a related ficld, and a thoroughknowledge of fundamenltal genetics at the whole plantand molecular level is required. Research will be directedtoward soybean improvement. Participation in the genet-ics teaching program is expected. Direct applications to:Dr. M. W. hillips, Head, e t oAronomy,Purdue University, West Lfaytte, IN 47907. In-dude a r6sumi, transcripts of all University degrees, andthrec letters of end . An Eq OpportuntylAffirmativeAction Epoyfer.

PLANT PHYSIOLOGISTThe South Dakota State University Biology Depart-

ment invites applications for a 9-month, tenure-trackposition at the assistant professor level. The positionrequires undergraduate teaching of plant physiology andrelated graduate courses, guidance of graduate studentresearch in plant physiology, and ability to obtain extra-mural funds to support an active research program. Theapplicant must have a Ph.D. degree with a specializationin plant physiology. Postdoctoral researeh experience inplant cell physiology is preferred. Applicants shouldsubmit by 18 April 1988, curriculum vitae, names andaddresses of three refcrences, a one-page statement ofteaching goals and research objectives, and transcripts to:Dr. C. H. Chen, Biology Department, South DakotaState University, Box 2207B, Brookings, SD 57007.Affirmaiv Action Opportunity/EqualEm ent Oppor-tunity Emplyr FIM.

POSTDOCTORAL ASSOCIATE: NIH-fundedproject to study the neuroanatomy of the brain stemgustatory system. Experiments involvc EM-HRP andautoradiography. Experience in neuroanatomy, immun-ohistochemistry or neurophysiology desirable. Send cur-iculum vitae and statement of research interests to: Dr.Mark C. Whitehead, The Ohio State Uniesity,Collegc of Dentistry, Deparlbncnt of Oral Biology,305 West 12th Avenue,CoIlmbus, OH 43210.

SCIENCE, VOL. 239144

POSITIONS OPEN POSITIONS OPEN

CIBA-GEIGY, a worldwide leader in ethical phar-maceuticals, has three positions open in its DrugDiscovery Profiling Unit in Summit, NJ. All three posi-tions require a demonstrated interest in phar-macological approaches to receptor function at themolecular level with emphasis in the followingtherapeutic areas; inflammation, osteo and rheumatoidarthritis and atherosclerosis.The first position is for a PhD with 2-5 years of postdoc-toral experience and a proven record of independentresearch capabilities. This is a supervisory position withresponsibility for providing RIA support to otherresearch groups on the Summit site. Good interper-sonal skills and the ability to interact with outsideclinical investigators would be advantageous. In addi-tion, this individual is intended to provide the Unit witha strong focus in immunologically related diseasemodalities. Experience in receptor related research atthe molecular level is essential.The second position is for a BS/MS level with abackground in biochemistry and/or pharmacology.

The third position is at the postdoctoral level for a per-son with a background in neuromodulatory peptideresearch and/or immunology interested in investigatingreceptor function in peripheral tissues usinghomogenate/intact tissue radioligand bindingtechniques.All three positions require a strong sense of teamworkand the ability to focus on goal-oriented researchrelated to drug discovery. The opportunity exists tointeract with multidisciplinary therapeutic researchunits in the areas of atherosclerosis, inflammation andcardiovascular. Publication of experimental data is ac-tively encouraged.CIBA-GEIGY is located in a pleasant suburban environ-ment in close proximity to New York City and offerscompetitive salaries with appropriate benefits. Pleaseforward your resume, to: Mr. Al Aronson, The Phar-maceuticals Division, CIBA-GEIGY Corporation, Dept.389, 556 Morris Avenue, Summit, NJ 07901. We arean equal opportunity employer mi/f/h/v.

Science Serving Mankind

CIBA-GEIGY

Opportunities In BiotechnologyRepligen Corporation is a leader in the application of Biotechnology to the health care and personal care markets. We arecurrently developing an AIDS vaccine and AIDS therapeutic products, products for the treatment of infectious diseases,cancer therapies and novel blocompatible personal care products. We take pride in the high caliber of our scientific staff andour collaborations with major research institutions and corporate partners In Europe and the United States. The expansion ofour efforts has created the following opportunities:

Molecular BiologyResearch Associates (200-9/26), MS or BS with 2 or more years' experience in Molecular Biology, Biochemistry or relatedfield. Two openings exist for individuals having experience with gene cloning, sequencing and expression in procaryotic oreukaryotic systems; immunological and protein chemistry techniques helpful but not essential.

Biorganic ChemistryResearch Associate (200-30), BSIMS in Biology, Chemistry or related field. This position in Biochemistry requiresexperience in enzyme purification and characterization. Relevant experience in assay development will be an advantage. Successfulcandidate will work independently as a member of a project team.

Research Associate/Research Technician (200-13), BS/MS. This position requires a solid background inchemistry or biochemistry. Experience with analytical techniques will be considered a strong asset.

Repligen Corporation offers a competitive salary, excellent benefits and equity participation. Please submit a cover letter, resume andreferences to the Director of Human Resources, Repligen Corporation, One Kendall Square, Building 700, Cambridge, MA02139. (Please refer to job code number when applying.) An Equal Opportunity Employer.

0

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NPOSITIONS OPEN

PLANT PHYSIOLOGIST/MODELERIncumbent will assume project scientist role in the

design and conduction of air pollutant effects studies onphysiological/growth responses of forest seedlings andsaplings, and in developing physiological process modelsfor simulating and predictig the response of maturetrees to air pollutants from experimental studies. Appli-cants must possess a Ph.D. (or equivalent) in plantphysiology, forest science or dosely aligned disciplinerelating to tree physiology and plant process modeing.Experience with the effects of air pollutants on plants isdesirable. Send cover letter, resume, transcripts (unoffi-cial) and the names and addresses of three references to:Ms. Susan Carey, Northrop Services, Inc.-Environ-mental Sdences, 1600 S.W. Western Boulevard, Cor-vallis, OR 97333. Application deadline is 29 April1988. Equal Opportunity Employer.PIANT/SOIL MICROBIOLOGIST. The NifTAL

Project, a leader in biological nitrogen fixation andRhizobium ecology research, is recrwting a plant/soilmicrobiolgist with interests in plant-microbe symbioticsystems research and development. The candidate isexpected to develop an active research program, super-vLse research support personne and advise graduatestudents. A Ph.D. in soil microbiology, crop physiologyor forestry is required. Preference will given tocandidates with a proven ability to obtain extramuralgrant funds and experience in symbiotic associations withtropical trees. Submit r6sumr, reprints and drafts ofmanuscripts and names of three references to: Director,NifTAL Project, 1000 Holomua Avenue, Paia, HI96779.

POSTDOCTRAL ASSOCIATE available on site-specific targeting ofAIDS DNA. Background in molecu-in biophysics with experience in gel ectophoresis/DNA sequencing methodology desirable. Send curricu-lum vitae and three letters of recommendation to: Dr.James Dabrowiak, Department of Chemistry, Syra-cae University, Syracuse, NY 13244-1200. Dead-line: 1 April 1988. An Equal OpportunityAffirmativeAaion Employer.

POSTDOCTORAL FELLOW: Cellular pharmacol-ogy ofprolactin related to proliferation, drug effects, i.e.,TCDD and cydosporine on receptor binding, PKC,onithine decarboxylase. Cell culture, RIA or EIA, West-em and Northern blots. Opportumnity to uncover newinsight into cell function related to proliferative diseases.Salary commensurate with NIH guidelines. Resume to:Diane H. Russell, Ph.D. Chair, Deprmt of Phar-macology and Therapeutics, Unmrsi of outhFlorida College of Medicine, 12901 30th Steet,MDC-9, Tampa, FL 33612.

POSTDOCTORAL FELLOW. A position is openimmediately for a Ph.D. with experience in moleculargenetics (including doning and expression) to participatemi researh using transgenic mice as animal models forAlzheimer disease, Down syndrome, and other humanchromosomal disorders.Send curriculum vitae, reprints, and names of three

rferenccs to: Dr. Charles J. Enstein, Department ofPediatics, Universi of Cafornia (1CSF), SanFrancsco, CA 94143-0106. UCSF is an AffirmativeActioEqual Opportunity Employer.

POSTDOCTORAL FELLOW-NEUROBIOLOGY

A position is available immediately for a postdoctoralfellow (2-year duration) to isolate cDNAs/gencs forreceptor protcins that are relevant to the nervous system.Cloning will be followed by studies on structure/functionrelationships of roceptors and on the mechanisms thatregulate their gene expression. Candidates with a strongworking knowkdge in molecular biology will befavored;however, competent applicants with a related back-ground will be considered. The research will be carriedout at the newly established Fishberg Research Centerfor Neurobiology, in collaboration with the Departmentof Psychiatry at the Mount Sinai School of Medicinelocated opposite Central Park on Fifth Avenue, a fewbklcks "upstream" from the Guggenheim Museum. Sala-ry: $22,000 per annum. Please contact: Dr. JurgenBrosius, Ccntre for Neurobiology and Behavior, Co-lumbia Univrty, 722 West 1&6 Street, New York,NY 10032. Telephone: 212-960-2245. An Equal Op-porunity Eployer.

POSTDOCTORAL FELLOW/RESEARCH AS-SOCIATE in neurophysiology sought to study thecaninc model of the sleep disorder narcolepsy. Thesuccessful candidate will work in conjunction with exist-ing eprse in in vivo voltammetry and dialysis. Amultidisciplinary approach to examination of this disor-der is underway in the lab ofW. C. Dement at StanfordUnivcrsity, encompassing analytical neurochemical, re-ceptor pharmacological, neurommunnological, and mo-kcular immunogenetic approaches to both human andcanine forms of narcolepsy. Send curriculum vitae andthree reference letters to: William C. Dement, MD.,Ph.D., Sloep Research Center, Department ofPsychi-atry TD-114, Stanord University School of Medi-cie, Stanford, CA 94305.

POSTDOCTORAL FELLOW/RESEARCH AS-SOCIATE POSMONS available to study the neuro-biological and molecular bases of sleep and its disorders.At Stanford University a multidisciplinary approach isunderway to understand fundamental sleep mechanismsand sleep disorders, integrating expertise in analyticalneuhc , receptor pharmacology, ne -logy and mo ecular biology, as well as conventionalskep-state neurophysiology. Areas of research interestinclude neural and molecular bases of sleep, circadianrhythmicity, and mammalian hibernation. We particular-ly seek highly qualified and highly motivated individualswith expenience in cellular neurophysiology, analyticalneurochemistry, and/or molecular biology. Send curricu-lum vitae and three reference letters to: W. Craig Hcller,Ph.D., Sleep Research Center, Department ofPsychi-atry TD-114, Sanford Univty School of Medi-cine, Stanford, CA 94305.

POSTDOCTORAL FELLOWSI have several postdoctoral Positions available in my

laboratory beginning 1 July 1988. Persons who have abackground in pharmacology, physiology and biochem-istry and who have an interest In cardiovascular pharma-cology and physiology or in diabetes mellitus are urgedto apply. A minimum of 1 year of funding is available,and it is hoped that the applicant would be eligible forfellowship funding for future years. Experience m isolat-ed cardiac preparations and routine biochemical assayswould be an asset.

Please write and enclose curriculum vitae and thenames of three referees to:

John H. McNill, Ph.D.Professor and Dean

Faculty of Pharmacetical SciencesThc University of British Columbia

2146 East MallVancouver, B.C.

V6T iW5Tclephone: 604-228-2343

POSTDOCTORAL POSMON in the design,preparation, and devclopment of new biodegradable,polymer-based delivery systems for vaccines with particu-

phasis on application to sub-unit vaccines. Musthave Ph.D.in polymer chemistry, pharmaceutical chem-istry, chemical aegneernmg, or related discipline. Salary$21,000, plus fringe benefits. Send resumc and twoletters of reference to: Professor Robert J. inhardt,College of Pharmacy,U ity of Iowa, Iowa City,IA 52242. The Un y ofowa is anAffirmativeActionEqual Opportunity E r.

POSITDOCIT)RAL POSITIONUNIVERSITY OF CALIFORNIA, IRVINEA position to study the control of gene expression

during morphogenesis in the opportuistic pathogenCadda alncans. Studies will involve gene cloning andtransformation, together with other modecular biologicaltechniques. Excellent training opportunities in moleculargenetics in eukryotic microbes. Send curriculum vitaeand three letters of reference to:

Paul S. SypherdDepartment ofMirobioloy and Molecular Genetics

College of MedicineUniversity of California

Irvinc, CA 92717AnAffinmtiveActinmlEqua Opporunity Employer

POSTDOCTORAL POSMON available for a bio-chemist, chemist, or cell biologist to study specificproteases in biological and medcal research using anewly developed technique. Send resume and threeletters of recommendation to: Professor C. W. Wu,Department of Pharacological Sacinces, SUNYStony Brook, Stony Broo,NY 11794. SUNY StonyBroolt is anAffirmaeAcion/Equal Opportunity Eduratorand Employer. AK #51.

A POSTDOCTORAL POSMON is available tostudy the role of idiotype recogition in the humoralresponse to HIV infection and also in the context ofauto-anti-idiotypic rcsponses to ligands of physiologicalreceptors. Projects involve T-celarecognition of sdio-types, studies of auto-anti-idiotypic responses, and prep-aration of monodonal auto-anti-idiotypic antibodies tophysiological receptors. Experience with the applicationof recombinant D5NA technology to immunoglobulingenes is preferred. Send curriculum vitae and names ofthree references to: Dr. W. L. Cleveland, DepartnltofMicrobiology, Columbia University, 701 Wes 168Street, New York, NY 10032. Telephone: 212-554-6929. Position is offered through: The Department ofMedicine, St. Lu 's/Rooevelt Hospital Center, 428West 59th Street, New York, NY 10019. An EqualOpportunity Emplyr MIF.

POSTDOCIORAL POSMON for recent Ph.D.beginning July to September 1988 to study signal trans-duction mechansins in chondrocyte differentiation.Modulation and reexpression of this phenotype are re-versible and the latter is induced by change in cell shapeor microfilament modification [JCB 106, 161-179(1988)]. Research experience in biochenistry/cell biolo-gy is preferred. Send curriculum vitae inmuding detailedsummary of rescarch experience and three letters ofrecommendation to: Dr. Paul D. Benya, OrthopaedicH tal, 2400 South Elower Sect, LosACA %W07-2697.AnAffirmaiv AaiolEqual O/ennity Emnployer-

POSTDOCTORAL POSMONHARVARD MEDICAL SCHOOL

Available 1 July 1988. Organic chemist will synthesizeradionuclide carrier molecules as part of a multidis-ciplinary program studying the toxic effects of internalemitters m cancer radiotherapy. Salary contingent onexperience (NRSA Guidelines). U.S. citizenship or per-manent residency status required. Please contact: Dr. A.L. Kas, HarvardMedicl School, SWRL, 50 BinneyStreet, Boston, MA 02115. Tcelphone 617-732-2184.An Eqal OpportunitylAffirmativeAction Employer.

POSTDOCTORAL POSMON. Study processingof macromolcules and receptor ligand interactions bybile duct epithelial cells. The applicant should be a recentPh.D. with a strong background in cell biology andcxperience in morphology and cell culture. Send curricu-hlm vitae, summary of research experience, and names ofthree references to: Dr. N. F. LaRusso, Mayo MedicalSchool, Rochester, MN 55905.An Equal OpportunitylAffirmatieActon Ititutn.

POSTDOCTORAL POSMON availabk for cecl/mokcular biological/immunological studies ofthe mech-anisms of subcellular compartmentalization of p-gluc-uronidase within the endoplasmic reticulum [Medda etal., Cel 50, 301 (1987)]. Available immediately. Sendcurriculum vitae and names and addresses of three refer-ences, and description of research experience and inter-csts to: Dr. Richard T. Swank, Roswell Park Memori-al Institute, 666 Elm Street, Buffalo, NY 14263. AnEqual OpportunityAffirmatiweAation Employer.POSTDOCTORAL POSMIION available immedi-

ately to study bacterial degradation of organic pollutantsfound in groundwater. Emphasis is on development andstudy of strains able to degrade substitutedmaromaticcompunids. Background in microbial Physiology, mo-=eCu biolgyo, and strain construction helpful. Positionis at Tyn Air Force Base, Panama City, Florida.Annual stipend range is $30,800 to $34,500. Doctoraldegree received within 3 years of starting date required,as Is U.S. citizenship or PRA status. Contact: Postgrad-uate R a dall, University Pr Pms -

sion, Oak Ridge Associated Unversities, P.O. Box117, Oak Ridge, TN 37831-0117. Telephonc: 615-576-3190.

SCIENCE, VOL. 239I450

POSITIONS OPEN POSITIONS OPEN

DIRECTORResearch& Development5 Prime - 3 Prime, Inc. has an immediateopening fora dynamic individual to directasmall, creative R&D group focused on thedevelopment of products for use in recom-binant DNA research. The Company is seek-ing a proven leader with a record of signi-ficant scientific contribution in MolecularBiology, Prior product development experi-ence in an industrial setting is preferred. Theposition requires a Ph.D. in MolecularBiologyor Biochemistry.The Company, located in the attractivesouthwestern suburbs of Philadelphia, offersan entrepreneurial environment with un-limited opportunity for personal and profes-sional advancement. The right candidatewill be eligible for an extremely attractivecompensation package.

Send C.V. and 3 References to:Director, Scientific Recruitment5 Prime - 3 Prime, Inc.19 E. Central AvenuePaoli, PA 19301(215) 644-4710

5 Prime_ 3 Prime, Inc.

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POSTDOCTORAL RESEARCH SCIENTISTBIOCHEMICAL TOXICOLOGY

The Upjohn Company, a leader in research and development of pharmaceuticals,currently has an opening for a Postdoctoral Research Scientist in the Pathology and Toxi-cology Research unit.The candidate selected for this position will participate in a research program studyingthe biochemical mechanisms of drug-and/or chemical-induced toxicity. Additionalobjectives include the development of new models/methodologies for the assessmentof toxicity in animals or other test systems, and evaluation of their relevance to potentialhuman health effects. Research results will be communicated to the world-widecommunity through publication in peer-reviewed joumals.Candidates should have a Ph.D. in toxicology or a closely related field and 0-3 yearspostdoctoral experience, with demonstrated experience in the biochemicaVmechanisticapproach to toxicology. Additionally, the candidate should possess excellent interper-sonal skills to allow effective collaboration with scientists in Pathology/Toxicology andother research units.Kalamazoo is a medium-sized Southwestern Michigan community with immediateaccess to a mix of excellent cultural, educational and recreational pursuits, includingnumerous lakes and a four-season climate. Upjohn offers a very competitive salary,commensurate with experience and an outstanding benefits program.For confidential consideration, please call toll free 1/800/253-8600 ext. 3-6767, (insideMichigan call collect 616/323-6767) to request an employment application be sent to you.Please refer to Ad Number 20858-F when calling.

An Equal Emplyrnent Opportunky Empoyer M/FOur commitment to scdntific excellence conlnues...

SENIOR RESEARCH SCIENTISTACQUIRED IMMUNODEFICIENCY SYN-DROME (AIDS) PROGRAM, National In-stitute of Allergy and Infectious Diseases(NIAIDINIH) is seeking a senior level scien-tist in microbiology (to include virology), im-munology or molecular biology, to serve as

Chief of the Pathogenesis Branch. Respon-sibilities of the position include planningand directing major extramural research ef-forts in the areas of basic research into thebiologic properties, molecular biology, andhost response to infection by HIV and its se-

quelae in order to improve the basicunderstanding of the causative agents, toimprove diagnostic and prognostic in-dicators, and to develop and improvemethods of prevention and treatment. Ap-plicants should have a Ph.D.; a broadbackground in microbiology, virology, im-munology and molecular biology; postdoc-toral laboratory research experience; ex-

perience in research program administra-tion; publications in recognized referencedjournals in field of scientific expertise, andknowledge of Federal Government extra-mural research program administration.

Salary range is $54,907 to $71,377. U.S.citizenship is required. Send curriculum vitaeto: Daniel F. Hoth. M.D., Acting Director,AIDS Program, NIAID, NIH, Building 31,Room 7A48, 9000 Rockville Pike, Bethesda,Maryland 20892.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

Opportunities in BiotechnologyFor over 25 years, we have been investing our time and resources in thefuture of biotechnology. Today, our investment is paying off with outstand-ing career opportunities in this rapidly expanding field. CollaborativeResearch is a leader in the development, manufacture and marketing ofbiotechnology products and services for healthcare and industry.

HUMAN GENETICS -Post docs (temporary; 2 year positions)Scientific Computer Applications - We seek an individualwith research interests in applicatons of computing to human moleculargenetics. Responsibilities will be to work with a Mathematician/MolecularBiologistn developing techniques for applying linkage analysis with DNAmarkers to the study of quantitative traits and complex diseases. A PhD inGenetics, Molecular Biology, Biology or Mathematics, programming ability,and knowledge of saistics are essential. Experience with molecular clon-ing techniques is desirable.Molecular Geneticist - We are also seeking a MolecularGeneticist with expertise in staof-the-art molecular techniques to applyto the genetics ofhumans and the development of medical diagnostics. Theposition requires a PhD in Genetics, Molecular Biology or related disciplineFor consideration, please submit your CV, list of publications and the namesof 3 references to the Human Resources Dept.,(10), Collaborative Research,Inc, Two Oak Park, Bedford MA 01730. An equal opportunity employer.

Where new techologies come to life

Coxlabo~research',,IncoqxaIed,4ff

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U.S. PATENT AND TRADEMARK OFFICEPOSITION: MicrobiologisVPatent Examiner Opportunity in-volves the scientific and legal evaluation of patent applica-tions involving recombinant DNA, molecular and cellularimmunology, molecular genetics, microorganisms, cell biolo-gy, cell culture, fermentation, enzymology or clinicalchemistry.OUAUFICATIONS: A full 4-year or longer professional curric-ulum in an accredited college or university leading to aBachelor's Degree or higher with specific study in MolecularBiology, Biochemistry, Immunology, Enzymology, Embryolo-gy, Protein Chemistry, Microbiology or Cell Biology.A Ph.D. or M.S. degree with relevant research experience ispreferred. A B.S. degree with significant research experiencewill be considered.Research Experience in any of the following areas would bebeneficial: DNA cloning, protein chemistry, gene expression,sequencing techniques, muteins, hybridoma technologies,monoclonal antibody applications, mammalian or plant celllines, cell culture, immunossays, hybridization techniques,fermentation, enzymatic reaction, diagnostics and automationof clinical analysis.SALARY: Dependent upon experience and qualifications.LOCATION OF POSITION: Arlington, VAFor further information contact:

Patent and Trademark OfficeOffice of Personnel, C&ECPK 1, Suite 700Washington, D.C. 20231703-557-3631Toll free: 800-368-3064

ZOOLOGICAL INSTITUTEUNIVERSITY OF BASLE-

SWITZERLANDTwo assistant positons are foreseen for 1 October 1988 inEvolutIonary Ecology and PopulaIon Blology. Successfulcandidates will have d ated originality, rigor and productiv-ity in using evolutonary insights to solve problems in ecology,genetic or behavior. One position will go to a person who canteach ethlogy and socioblogy, but research in this area is not apre-requisite. Quality of research and prospecs for fitting into astrong working group are more important than the particularquestion asked or the particular organism used. We seek abalance within the group between field and laboratory and be-tween theory and experiment.

A doctoral degree and the ability to teach immediately in Germanare both required, and 2-3 years of postdoctoral experience ispreferred. Successful candidates will be expected to direct inde-pendent research programmes, to seek their own grants, to offeran upper division undergraduate course in the area of theirexpertise and to teach in the core courses of the Zoologycurriculum.

The term of appointment will be 3-5 years, and the salary will be inthe range SFr. 50,000-70,000. Both will depend on experienceand qualffications. Habilitation will be possible.Please send a curriculum vitae, representative reprints and thename of two references by 30 April 1988 to:

Professor S. SteamsZoologlsches lnstitutUniversltAt BaselRheinsprung 9CH --4051 BaselSwIzerland

0tsAgracetus N

ResearchAssistants!Technicians

Agracetus, a world leader in agriculturalbiotechnology, seeks innovative and self-motivated individuals to join our plantgenetic engineering group. They will be partof an exciting program directed towardsunderstanding and developing genetransfer and expression in plants. Candi-dates must have a B.S. or M.S. degree wrthone or more years laboratory experience inmolecular biology. Letters of applicationshould include a detailed description ofexperience with recombinant DNAtechniques.We offer a competitive salary, a compre-hensive benefits package and advancementopportunity.Please send your resume to: PersonnelDepartment, Agracetus, 8520 UniversityGreen, Middleton, WI 53562.

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICS ABOUT YOUR PROPOSEDLAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

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Sandoz Pharmaceuticals Corporation is responsible forproducts that improve the quality of life. Our develop-ments are the result of research conducted by profes-sionals who specialize in many different fields.

The Sandoz Research Institute is seeking seniorscientists to play vital roles in molecular biologyresearch. These positions offer unique opportunitiesto develop creative, independent research programsutilizing recombinant DNA and other molecular bio-logical technology to identify novel therapeutic ap-proaches in the following areas: glucose regulation anddiabetes mellitus, lipoprotein metabolism and athero-sclerosis, monoclonal antibodies, and platelet activatingfactor and other mediators of inflammation and immunefunction. Successful candidates will work closely withinterdisciplinary teams of intramural scientists andcollaborate with extramural scientists.

Joseph P. Castellano/\ Director, Human Resources 403/1

SANDOZ RESEARCH INSTITUISANDOZPHARMACEUTICALS CORPOREast Hanover, New Jersey 07936An Equal Opportunity Employer M/I

Requirements for these positions include a Ph.D. inMolecular Biology or closely related discipline, and aminimum of 2 years' postdoctoral experience in mole-cular biology preferably with emphasis on eukaryoticgene expression. In addition, you must have demon-strated ability to plan sound scientific projects, toconduct innovative independent research, to achieveresearch goals and to make significant intellectual con-tribution. A record of significant publications in majorscientific journals as well as excellent written and oralcommunication skills are also required.Positions at Sandoz offer personal satisfaction, profes-sional opportunity/challenge, competitive salaries andan excellent benefits package. Our campus-like facilitiesare conveniently located in northern New Jersey.For prompt consideration, please forward your resumeand salary requirements in confidence to:

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Immunopharmacology at Smith Kline & French Laboratories, locatednear Valley Forge, Pennsylvania, is seeking to fill several positions.These include a postdoctoral scientist in collaboration with the Depart-ment of Molecular Pharmacology and two outstanding scientists at ei-ther the Senior Investigator or Associate Investigator level. We are ex-panding current research programs studying the cellular-molecularpharmacology of supressor cells, and mechanistic studies of cytokineand ligand-receptor interactions, and immunoregulation.Suppressor Cell Pharmacology (RI 1)We are seeking a Postdoctoral Scientist to join a multidisciplinary teamstudying the cellular and molecular pharmacology of supressor cell in-duction in an attempt to design novel therapeutic strategies for immuno-regulation. The successful candidate will use a variety of in vitro and invivo techniques to identify and characterize suppressor cell populationsresulting from pharmacologic induction as well as the cellular and mo-lecular mechanisms underlying these events.We consider postdoctoral studies of major importance in an individuarscareer and encourage publication of findings in leading journals and fullinteractions with the scientific community. Our postdoctoral appoint-ments are normaly for two years duration. Candidates are required tohave:* Ph.D. in Immunology or Cellular Biology with 0-2 years Postdoctoral

experience.* Experience in in vitro and in vivo models of immunoregulation.

* Knowledge and interest in receptor interactions and molecular as-pects of cell activation.

Immunopharmacology (RI 2)We have two openings for Senior Investigators (4-6 years postdoctoralexperience) which could be filled at the Associate Senior Investigatorlevel (24 years postdoctoral experience). These individuals will be in-volved in a multidisciplinary research effort focused on mechanistic andimmunoregulatory studies of receptor-ligand interactions for the devel-opment of novel immunodulatory/immunoregulatory moieties. Bothlymphocytes and macrophages are targets. Candidates are required tohave:* Ph.D. in Immunology or Molecular Immunology.* Expertise and/or practical knowledge in receptor-ligand interactions,

signal transduction and molecular immunoregulation.* A strong publication record.* Excellent oral and written communication skills.* Ability to interact with a multidisciplinary research team.We offer excellent compensation and benefits as well as an attractiverelocation policy. For confidential consideration, send your C.V. andnames of three references to: Robert F. Obst, Manager, Personnel Rela-tions, R0125, Smith Kline & French Laboratories, Research and Devel-opment Division, P.O. Box 1539, King of Prussia, PA 19406-0939. In re-sponse please refer to the above reference number. We are an equalopportunity employer, M/F/H/V.

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POSITIONS OPEN

(Anticipated) POSTDOCTORAL POSMONavailable 1 August 1988 for studics on the control of iontransport in freshwater mussels. Experience in enzymeassays, use of isotopes and/or scparation techniques(HPLC) prefcrred. Scnd curriculum vitae and threeletters of recommcndation by 15 April 1988 to: Dr. T.Dietz, Department of Zoology and Physiology, Loui-siana State University LX), Baton Rouge, LA70803-1725. LSU is an Equal Opporunity Employer.

POSTDOCTORAL POSITIONHUMAN TUMOR IMMUNOLOGY

A position is available 1 September 1988 to study thercgltion of anti-tumor immune responscs in patientsreceiving immunotherapy for melanoma. Applicantsshould havc Ph.D. or M.D. with experience in ccllularimmunology. Send curriculum vitae and refcrences to:Dr. Davi iAcrd, Thomas Jefferson University, 1015Walnut Street, Suite 1005, Philadelphia, PA 19107.

POSTDOCTORAL POSITION INAIDS IMMUNOLOGY

Position available now to study mechanism of cellularimmunity to HIV. Our laboratory is utilizing human Tcell dones and HIV envelope and core pcptides to defineT cell-dependent epitopes of the virus. An active multi-disciplinary program with biochemists, molecular biolo-gsts and cinicians is availabk. Please send curriculumvitae and names of threc references to: Daniel Stites,M.D., Box 0100, University of California, San Fran-ciso, CA 94143. The Uneity of Cal!fornia is anAffirmatimeAcinlEqua Oportunity Employer.

POSTDOCTORAL POSMON available immedi-ately to carry on genetic engineeinn of and to studyregulation of gene for histidine drboxylase from Lac-tobaciluxs. Background in microbial genetics is desirable.Send curriculum vitae, short r6sum6 oflaboratory expen-ence, and names of three references to: Jon Robertu,Department of Chemistry, University of Texas, Aus-tin, TX 78712. Telephone: 512471-3175.

POSTDOCTORAL POSMON available immedi-ately for project invohling molecular mechanisms ofchemical carcinogenesis, induding detection of onco-genes and growth factors in preneoplastic and neoplasticoral mucosa. Experience with cell culture and immuno-cheiustry desirable. Send curriculum vitac with names ofdtree refercnces to: Dr. Dennis Solt, NorthwesternUniversity, Departnent of Pathology, 303 East Chi-cago Avenue, Chicago, IL 60611.

POSTDOCTORAL POSMONS available in De-partments ofAnatomy, Biochemistry, Microbiology andImmunology, Pharmacology, and Physiology. Appli-cants must have a Ph.D. or M.D. degree. Positionsavailable during 1988 to 1989. Closing datc: 1 October1988, or until positions are filled.Send applications to appropriate department head:

Univcrsity of Arizona Hcalth Sciences Cen-ter, Tucson, AZ 85724.An Equal OpportunitylAffirma-tiveAction/Titk IX/Sectio 504 Emplyer.

POSTDOCTORAL POSIMONS available imme-diately for biochemists, biophysicists, and molecularbiologists to study (i) the mechanism and regulation ofgene exprcssion in both prokaryotic and cukaryoticsystems, and (ii) the nuclic acid-protein interactionsSend resume and three letters of recommendation to:Professor Cheng-Wen Wu, Department of Pharma-cological Sciences, SUNY Stony Brook, Stony Brook,NY 11794. SUNY Stony Brook is an Affirmative AaionlEqal Opportunity Educator and Employer. AK #52.

POSTDOCTORAL POSITIONS arc available tostudy mechanisms ofhepatic glutathione metabolism andtransport (with Dr. N. Ballatod) and molecular mecha-nisms of metal transport and toxicity (with Dr. ThomasW. Clarkson). Experimental models currently in use inour laboratories indude plasma membrane vesides, iso-lated hepatocytes, and the perfused rat liver. Please sendcurriculum vitae, repmnts, and names of three referencesto: Dr. Thomas W'. Clarkson, Environmental HcalthSdcenes Center, Univcrsity ofR School ofMedice, Rodester, NY 14642. The Univrm ofRoctr i an Eqal OpportunityL4ffirnnma Acton Em-ployr.

POSTDOCTORAL POSMON IN MOLECU-LAR NEUROBIOLOGY to work on the molecularbiology of sodium channel isoforms, induding cardiacsodium channel. Cloning, expression, structure-functionrelationships. Applicant should have strong backgroundin recombinant b]NA technology. Excellent environmentavailable through strong interdepartmental p m incell physiology inducing patch-clamp electrophysiologyin adjacent lbs. Send currculum vitae and two to eletters of reference to: Richard B. Rogart, M.D.,Ph.D., Department ofMedicne, Hospal? Box #249,University of Chicago, 5841 South Maryland Ave-nue, Chicago, IL 6067.

POSTDOCTORAL POSMONS available imme-diately for studies of HIV immnunochemistry and immu-nobiology. Areas of research interests include develop-ment ofyan effective synthetic peptide vaccine (Dr.Gordon Dreemn); idiotype-anti-idiotype network,gene cloning, immunoglobuliui variable regon sequenc-, and peptide chemistry (Dr. Ronald C. Kennedy)

definition of HIV B and T cell epitopes, murine andhuman monoclonal antibodies and human T cell doning(Dr. Tran C. Chanh); and simian immunodeficiencyvirus (Dr. Jonathan S. Allan). Annual salaries rangefrom $20,500 to $23,920, dependent upon ecpericnce.Please mail curriculum vitae with names and telephonenumbers of three references to: Personnel Director,Southwest Foundation for Biomedical Research,P.O. Box 28147, San Antonio, TX 78284. EqualOpporunity EmployerM/F.

POSTDOCTORAL POSITIONSDRUG TARGETING

RESEARCH PROGRAMUNIVERSITY OF SOUTHERN CALIFORNIAPositions available immediatcly for recent Ph.D.'s in

biomedical or pharmacutical sciences to particpatc inmultidisciplinary research projects cmphasizing biologi-cal, biochemical, and pharmacokinetic aspects oftargeteddrug delivery. Currcnt rcsearch projects include: (1) Dr.James D. Adams, "Mechanisms of induction of Parkin-son's disease by MPTP"; (2) Dr. Kenneth Chan, "Phar-macokinctics of metabolic activation of drugs usingstabk isotope methodology"; (3) Dr. Karl Hwang,"DnT rgeting to hepatocytes and macrophage actva-tion y (4) r. Robert Koda, Transdealdrug delivcry and drug disposition"; (5) Dr. Vincent H.LLee, "Drug targetng to the eye and mucosal peptidedelivcry", and-(6) Dr. WeChiang Shen, "Endocytosis,tnsosis, and intracellular processing of dmg conju-gates". Interested persons should send curriculum vitaeto the appropriate faculty member at: Universi ofSouthern California, School of Pharmac, JohnStauffer Pharmaceutical Sciences Center, 1985 ZonalAvenue, Los Angdes, CA 90033. Equal OppotunityExqkyerrM/F.

SAINSBURY LABORATORYMOLECULAR PATHOLOGY OF PLANTS

POSTDOCTORAL ANDRESEARCH ASSISTANT POSTS

The Sainsbury Laboratory, which is being establishedat the John Inncs Institutc, Norwich, will undertakebasic rsearch with the eventual aim of developingdiseasc-resistant crop plants. It has becn set up with agrant of £15 million from David Sainsbury through hisGatsby Charitable Foundation.

Applications are invited for postdoctoral and researchassistant positions to investiatc various aspects of theinteractions betwen plant viruses and their hosts. Thequalifications are an enthusiasm for a molecular approachand talent for laboratory work.Some positions will be availabk in the summer/au-

tumn of 1988 and it is cxpected that further recruitmentwill be in the summer of 1989 when the new laboratorybuiding will be complete. Further details can be ob-tained from: Dr. David Baulcombe, IPSR CambridgeLaboratory, Maris Lane, T n n, Cambridge.

Salaries wil be in the range £9,86 to£15,720 for thepostdoctoral positions and £8,675 to £11,680 for theresearch assistant posts. Contribury superannuation.

Aplications should be sent to: Tfe Personne Offi-cer, John Innes Institute, Colny Lane, Norwich,

and, NR4 7UH including full curriculum vitae andthe names of two refcrees. Pkase quote reference SIUB.

POSTDOCTORAL POSITIONYEAST MOLECULAR BIOLOGY

A position is available to join a laboratory investigat-ing mechanisms of genc cxpression in Saccharomycesacisia. Applicants should have a recent Ph.D. in

molecular biology, biochemisty or genetics. Send cur-riculum vitae and names and addresses ofthree referencesto: Dr. Lawrence W. Bergm, Clippinger Labora-tories, Department of Chenisty, Ohio University,Athens, OH 45701. An EquaW OpportunitylAffirmativeAction Employer.

POSTDOCTORAL POSITIONS IN SYNTHET-IC ORGANIC CHEMISTRY AND BIOCHEMIS-TRY (ITHREE). Synthcsis of carbocyclic and hetcrocy-clic compounds for carcinogencsis studies; in vitro and mvivo metabolism studics of drugs and cnvironmcntalcarcinogcns; 32P-posdabeling ofmodificd DNA adducts.Scnd curriculum vitac and names of three references to:Dr. Edmond J. LaVoie, Department of Pharmaceuti-cal Chemistry College of Pharmac, Rutg Univer-sity, PO Box 789, Piscataway, NJ 08855. Rutgers isanEqu Oppotnity/AffirmativeAtion Employer.POSTDOCTORAL POSMIIONS available to

study: (1) stucture and function of the receptor fortumor necrosis factor and (2) the cellular and molecularbiology of actions mediated by tumor necrosis factor innormal and transformed cclls. Rccent Ph.D. with train-ing in protcin purification, cellular, or molecular biologypreferred. Send curriculum vitae and names, and tcle-phone numbers of three references to: Dr. David B.Donner, Memorial Sloan-Kettering Cancer Center,1275 York Avenue, New York, NY 10021.

POSTDOCTORAIARESEARCHASSOCIATE POSMON

Postdoctoral/research associate position is available tostudy the structure and fiunction of dynein and otherflagellar ATPases. Experience in rapid-Tteeze/deep etchor immuno EM, cDNA cloning, in vitro translocation ofmicrotubules using video-enhnced DIC, protein phos-phorylation, amino acid sequencing, or selection andanalysis ofChlamydomonas mutants is desirable. TheWoreester Foundation offcrs cxcellent facilities, a stimu-lating atmosphere, and the op rtunity to carry outresearch unencumbered by teaching or administrtiveduties. Starting date negotiabk; salary commensuratewith experience. Scnd curriculum vitae and names ofthreerences to: Dr. George B. Witman, WorcesterFoundation for Experimenal Biology, 222 MapkAvenue, Shrebry, MA 01545.An Equal OppotsunityLAfwmafivAction Employer M/F/H.POSTDO)CTORAL OR RESEARCH ASSO-

CIATE, Yale School of Medicine. Position available forPh.D. to study neural plasticity and regeneration, neuro-glial interactions, cellular recognition in CNS/PNS, ormyelination. Incumbent will join multi-disciplinary re-search group (morphology, immunology, physiolgy,pharmacology) in new research center. Backgound Inneural transplantation, immunocytochemitry, ultra-structure or freexe-racture desirable. Send curriculumvitae and names of three references to: Stephen G.Waxman, M.D., Ph.D., Chairman, Department ofNeurology, Yale School of Medicne, 333 CedarStreet, New Haven, CT 06510. Equal OpportunitylAffirmativ Actio Employer.POSTDOCTORAL RESEARCH ASSOCIATE,

Ph.D. or M.D. to work on cell and molecular biologyof hormone receptors. Special emphasis is on the regula-tion of the glucocorticoid receptor in tumor cells andculture. Send curriculum vitae and names of three refer-ences to: Gerald Litwack, Fels Research Institute,Tempk University School of Medicne, 3420 NorthBroad Street, Philadelphia, PA 19140. An EqualOpportunytlAffirmativActown Eployer.POSTDOCTORAL RESEARCH ASSOCIATEoition available immediatcly for studies of ncurodevc-omen muants in Drosopbila. We are particularlyinterested in mutants that alfect neuronal determinationand selective connectivity in the adult nervous system.Genetic and/or molecular genctic xperience is desirable.Salary commnensurat with experience. Please send curric-ulum vitae and names of tee reerences to: Dr. ForaKatz, Howard Hughes Medical Institute, Unhersityof Txas Southwestern Medical Center, 5323 HarryHines Boulevard, Dafll, TX 75235-9050.

SCIENCE, VOL. 239145+

POSITIONS OPENPOSITIONS OPEN

I

Join a World leader in drugdelivery and make a difference

ALZA's innovative drug delivery systems make a real differencein people's lives. Here's how you can be part of the team.

Research Scientist - Biological SciencesA Research Scientist is required to participate in and coordinate aresearch program on the mechanisms and prevention of irritationin epidermal and mucosal tissues. Candidates should have exper-tise in microvascular physiology and,br the pharmacology of irri-tation. Experience in electrophysiology would also be desirable.The position requires a Ph.D. in an appropriate biological sciencetogether with significant postdoctoral experience.

Staff Scientist - ToxicologyA Staff Scientist is needed to ensure compliance with GLP regula-tions and to direct toxicology studies investigating issues of bio-compatibility and tissue irritation. The position requires a Ph.D. orequivalent in an appropriate biological science with subsequentexperience in experimental pathology, histology or surgery.

Please send your resume, indicating area of interest to ALZACorporation, Employment Department, 950 Page Mill Road, P.O.Box 10950, Palo Alto, CA 94303-0802. We are an equal opportunityemployer.

aiz

POSITION AVAILABLE

IMMUNOLOGISTThe 1Itmationa Laboratory for Research on Animal

(LRAD), is an internationally funded, mna-or instition with the mandate of developing im-prved methods to conrd two important diseases of

hbd 1001111 and theierios. The mul-fdisciplinary research program includes blomi-

try, molecuar bbbgy, in , cell biology,patoogy, parasigy, elecron mkcoscopy andentol omNoogy wih appropriate potg units.

Cabis are invited for position of:

IMMUNOLOGIST-POSITION REF: PD/6/88/1

A potdocoral position is availab in a muitidis-cipliny resarch group studying cellular immunerwpones of cattie to the proton parasite 77Te-smpavaThe 1UOSJ MWI1eWImwgthepr T cell respos specific for parasitsed cells,with the aim of dentin p ste antgens impor-ten in protectve immunity.

Applants wil have a PhD in immunology andrelevant exe of the analis of cell-mediatedimmune medcnisms. An initial veterinary qualirica-tion and/or exrience in ruminant immunology willbe edvand ge.

This is an International staf position and salry willbe paid in US dollars. Initial salary will be determinedby qualifiabons and experience. Scientic stat areepected to contrbut to the trainig program. Mov-ing, houing, commutation and education allow-ances are paid and there are medical and retirementbenefits. Applants should inciude current curricu-kim vitae and names and addresses of three refer-ees. Applications, cit the position reference num-ber, should be sent by April 15th, 1988 to:

The Chief Po-sennel OffIewILRADP.O. Box 3079

KenAR

MOLECULAR BIOLOGIST,IMMUNOLOGIST, VIROLOGISTThe Acquired Immunodeficiency Syndrome(AIDS) Program of the National Institute ofAllergy and Infectious Diseases (NIAID) ofthe National Institutes of Health is seeking aMOLECULAR BIOLOGIST, IMMUNOLOGIST,and RETROVIROLOGIST to join the TargetedDrug Discovery Section of the DevelopmentTherapeutics Branch. The Branch is respon-sible for planning and directing a federal pro-gram of extramural research projects for thediscovery and preclinical development ofpotential therapies for the treatment of AIDSand its associated opportunistic infections.Major efforts presently underway includegovernment-industry-academia cooperativedrug discovery groups, animal models forevaluation of immunomodulators, basicbiochemical, immunological and virologicalresearch directed toward targeted drugdiscovery, information exchange, data coor-dination, and planning of new initiatives. APh.D. in molecular biology, immunology,virology, or another related discipline is re-quired. Research experience in mammalianand/or prokaryotic expression systems,biological response modifiers, orretrovirology is desirable but not required.Experience with HIV or simian immunodefi-ciency virus (SIV) would be helpful. Salaryrange for these positions is $39-501 $60,683.

U.S. citizenship is required. Send curriculumvitae, bibliography and names of referencesto Dr. Margaret I. Johnston, NIAID/AIDS Pro-gram, Room 245p, 6003 Executive Boulevard,Bethesda, Maryland 20892.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

NEUROSCIENTmSPH.D. LEVEL

PHARMHACEUTICALRESEARCH

Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company,has an immediate opening for a scientist to join the Neuroscience Sectionwithin our Pharmacology Department. The selected candidate will have in-terest in neurotrophic influences on regeneration and degeneration in themammalian nervous system and will join a group work focusing on develop-ment of agents to treat neurodegenerative disorders such as Alzheimer'sDisease.Successful applicants will possess the following:*A Ph.D. in a neuroscience-related discipline* Experience in studying the biological actions of neurotrophic agents us-ing tissue culture or molecular biological approaches

* Excellent oral and written communication skills, as well as a documentedrecord of research excellence

We offer excellent compensation and benefits at our modern facilities ad-jacenttothe Universityof Michigan campus. Interested, qualified candidatesshould forward curriculum vitae and salary requirements to: Ms. S. Hultquist,Warner-Lambert/Parke-Davis, 2800 Plymouth Road, Ann Arbor Ml 48105.

"EOUAL OPPORTUNITY IN ACTION"

PARKE-DAVISDIVISKON OF WARNER-LAMBERT COMPANY

POSITIONS OPEN

POSTDOCORAL POSMIIONS IN PROTEINENGINEERINGFOLDING available June, 1988.Molecular genetic techniques are used to introduce spe-cific changes in protein primary structure. Mutation-induced changes in tertiary structure, internal dynamics,function, and the process of structure formation-pro-tein folding are evaluated with biophysical methods.

Applicants with interest in mokcular genetic or bio-physical aspects of the project are encouraged to apply.lease submit currculum vitae induding names and

addresses of three references to: Dr. Barry T. Nail,Biochemistry, Uversity of Tcxas Hcalt ScenceCenter, 7703 Floyd Curl Drive, San Antonio, TX78284-7760.POSTDOCIORAL RESEARCH ASSOCIATE po-

sition available immediatcly to study the molecular biolo-gy of membrane proteins and their rok in parasite attach-na nt ongoing projects incdude the invesigatonof the role of sialglycoproteins as malarial parasite rcep-tors and gene expssion of gIycohorin during dcvelop-mt. Expeienc in either molecu biology or in parasi-tobgy is desirable. Annual salary ofrs $18,000 to$24,000 commensurae with expenence. Submit curricu-hln vitae and two to: Dr. Donea J. Wilson,Division ofBimedicl Sdences, Meharry Medical Col-lege, 1005 D.B. Todd Boukvard, Nashville, TN 37208.Equal Oppwtuiy Emplo)r.POSTDOCTORAL RESEARCH POSMONS

available immediately to study molecular aspects of hor-mone action and aging. Opportunity to partcipate incollaborativc rsearch between the Division ofMolecularGenetics of the OB/GYN Department, and the Depart-ment of Cellular and Stutural Biology. Excellent re-scarch facilities including the transgenic core. Experiencein any one of the following areas is required: molecularcloning, DNA sequencing, mammalian transfection, ste-roid receptor analysis and enzyme purification. Sendcurriculum vtae with names ofthree refercnces to: ArunL Roy, Ph.D., Professor and Head, Division ofMolcular Gcentics, Department of Obstetrics andGynccology, University ofTcxas Health Scienc Cen-ter, San Antonio, TX 78284.An Equal Opporunity/AffinnativeAction Emplyfr

POSTDOCTORAIJRESEARCH ASSOCIATESIN PROTEIN BIOCHEMISTRY. Positions availablefor 3-year, federally funded study on hormonally regulat-ed proteins. Research involves purification,pde map-ping, sequencing, analysis of posmransltional modifica-non, etc. $18,000 to $24,000 per year commensuratewith experience. Submit curriculum vitae and names,addresses, and telephone numbers of three references to:Box 41, SCIENCE.

POSTDOCrORAL RESEARCH OR RE-SEARCH ASSOCIATE POSMON available on 1July 1988 in an ongoing research program studyingmetabolic responses of plants to interacting stresses,including air pollution. Individuals should have primarytraining in plant biochemistry and/or plant molecularbiology, with secondary training in plant physiologyagronomy, or other plant science. Send curriculum vitaeand names of three references to: Leonard H. Wein-stein, Program Director for Environmental Biology,Boyce Thompson Institute at Cornell University,Tower Road, Ithaca, NY 14853.An Equal OpportunityMffinnatimeAaton Emplyer

POSTDOCTORAL RESEARCH POSMON an-tici ted for Ph.D. neuroscientst to join multidis-ciplinary basal ganglia research laboratory in the Depart-ment of Neurology, Hahnemann University School ofMedicine in Philadephia. Position involves participationin neurocdmical, behavioral, and ekctrophysiolgicalstudies of experimntally induced parkinsonism and re-covcry of function following brain damage. Applicantwith neurochemistry or electrophysiology back4roundand wiingness to learn other techniques preferred.Position open beginning 1 July 1988. Send curriculumvitae, summary of research experience, outlinc of re-search/career objectives, and three letters of reference to:Dr. J. S. Schneider, De t of Neurology,UCLA School of Medicne, Reed N lo -

seach Center, Los Angels, CA 90024.Hahneman University is an Affirmative AaionlEqual

Opportunity Emplyner.

RESEARCH ASSISTANT, Ph.D. to study molecu-lar mechanisms of B cell deveiopment and genetics ofdifferentiation. Experience in molecular genetics, recom-binant DNA technology, primary tissue explantation andlong-term tissue cuultre, preparation of dendritic cellsandhlper T cells, and aworking knowledgee of immu-nology, bacteriology and virology required. Qualifiedpersons contact: Johanna A. Griffin, Department ofMicrobiology, Univ ofAlabama at Birmingham,Birmingham, AL35294.

RESEARCH ASSISTANTPROFESSOR, Depart-ment ofMedicine, Ph.D. in physiology or pharmacologywith postdoctoral fellowship in rena physiology and/orexpenmental hypertension. Knowledge of radioim-munoassay, chromatography, receptor assays desired.Will develop/direct experimental animal laboratory. Sendcurriculum vitae and three refercnces to: John Bauer,MD., Professor ofMedicinc, Unvrsiyq ofMissouri-Columbia, Columbia, MO 65212. AnAffi ative Ac-tionlEqual Oppounity Employer

RESEARCH ASSOCIATEDEVELOPMENTAL CENTER FOR

HANDICAPPED PERSONSThis position will study immune function and autoim-

mune mechanisms in patients with autism and theirfamily members. Opportunity exists for cventual ap-pointment to a professorial rank in appropriate academicdepartment. Earned doctorate in immunology, 2 years ofrelevant postdoctoral expcrience, and dcmonstratedexperience in performing immunologic techniqucs suchas tritiated-thymidine incorporation, chromium releaseand cell separation (a knowledge of flow cytometrytechniques is desirable but not required). Salary range for12-month position is $25,000 to $30,000, depending onexperience and qualifications. To apply, send letter ofapplication, curnculum vitae, and names of thrce refer-encs or lettrs of remmendation to: Dr. Reed War-ren, Devlomntal Centcr for Handicapped Persons,Utah State Univity (USU), Logan, UT 84322-6895. Review of applications will begin 8 April 1988.USU is an Affi A ActioEqual O it and

Immgratio Refgnw and ContolActEmpoyr.

A

POSTDOCTORL

POSITIONS

offmann-La Roche, a research-intensive pharmaceutical comparry locaed in suburbanNew Jerse, 12 rriles from New Ybrk City, is seeking Research Associates (post-doctoral fellows) with expertise in virology and immunobgy to join multidisciplinary

teams of cell biologists, molecular biologists, medicinal cherrists, protein biochemists and physicachemists. These positions will offer the successful candidates an opportunity to carry out basic researchwhile interacting with colleagues silled in translating relevant events into therapeutic approachesPublication of basic research results is encouraged.

VIROLOGYlwo positions are available for individuals to carry out AIDS research. We are seeking a Molecular

VItlegIst to study mechanisms of actlon of the tot and at regulatory proteins of human immunodefi-ciency virus. A molecular biology background is essential and aeperience in the area of regulation of geneexpression is desirable. The second positlon is for a Mlmelar BlelsosUtBebemt to investigatestructure/function reationships of HIV-encoded enzymes by site-directed mutagenesis. Experience inmolecular biology or protein chemistry is required.

IMMUNOLOGYTwo positions are available for Cellular lImusolglts to investigate (1) mechanisms involved in

macrophage recognition and cytolysis of tumor cells, and (2) the regulation of cytolytic lymphocyteresponses by cytokines, using both in vitro and in vivo models. Candidates should have a PhD in im-munology with a strong background in biochemistry or cefl biology.

Interested individuals should send curriculum vitae and names of three references to: Dr MIchal

Sherman, Dr r of Cell Biolgy, Roche Reseh Celu, NulNey, New Jesy 07111 We are an equalopportunity employer

Hoffunann-La Roche

Working Today For A Healthier Tomorrow.

ENGINEERSCollier County, in beautiful Na-ples, FL, has career opportuni-ties available for Engineeringprofessionals in several spe-cialty areas: Transportation,Water Management, Utilitiesand Environmental. Bachelor'sdegree with 2-4 years experi-ence required; Florida PE pre-ferred. Challenging positionsavailable due to exciting OneStop Community PermittingProcess. Salary to low 40's withexcellent fringe benefits.For further information and ap-plication, please call HumanResources COLLECT at (813)774-8465, or send resume andsalary history to:COLUERCOUNTY GOVERNMENT

Human Resources Dept.-E3301 E. Tamiami Trail

Naples FL 33%2Targeted Screening Date 5-188Equal Opportunity Employer

r..

POSITIONS OPEN POSITIONS OPEN

POLLUTANTTRANSPORT ANDREACTIONS IN SOILSOR INDOORATMOSPHERESThe Lawrence Berkeley Laboratory's IndoorEnvironment Program is seeking outstand-ing candidates for two positions devoted toperforming research on the behavior oforganic chemicals or of radon and its decayproducts inside buildings or in the groundnear building foundations. A Ph.D. or equiv-alent degree in chemistry, physics, geology,environmental engineering, or related fieldsis required, with substantial experimental ortheoretical capabilities applicable to inves-tigation of fundamental transport and reac-tion processes and their dependence onenvironmental and physical factors, eitherin or around homes and other buildings.Processes of interest include interactions ofspecific pollutants with other substancesand with interior surfaces or soils, as well astransport by convection or diffusion eitherin soil, into buildings or within them.

DIVISIONAL FELLOW (C/4580) Requires2-5 years' experience, in addition to thePh.D. and strong evidence of exceptionalresearch and leadership capabilities. Ap-pointment is for a 5-year term with the in-tention of subsequent promotion to theposition of Senior Scientist. The Fellow willinitially perform research in existing areas,with the expectation of developing new ef-forts, in either case undertaking a substan-tial and growing leadership role. Position re-quires capabilities and interest in conduc-ting fundamental and outstanding researchin an essentially interdisciplinary field, theability to work well with and stimulateothers, and a proven record of effectivecommunication and publication.POSTDOCTORAL FELLOW (C/4572)Available for an individual who has recentlycompleted the Ph.D. and demonstrated astrong capability for productive research inareas related to those of the program. Posi-tion is for one year, normally renewable fora second year.

Competitive salarycommensu rate with expe-rience, plus comprehensive benefits. Pleasesend resume, including publication list,names of references (must indicate Job C/4580or C/4572) to: Employment Office, LawrenceBerkeley Laboratory, 90-1012, 1 CyclotronRoad, Berkeley, CA 94720 (415)486-4226. AnEqual Opportunity Employer, M/F/H.

LAWRENCEBERKELEYLABORATORY

RESEARCH SCIENTISTReceptor Pharmacology

G.D. Searle, a worldwide leader in thepharmaceutical industry, now seeks a

Ph.D. Scientist to design and conduct studieson drug receptor interactions, and receptorisolation and characterization.Position also requires development of laboratoryand program-related objectives in the Molecular& Cell Biology group, and interactions with ap-propriate molecular biology staff regarding puri-fication and cloning of receptor molecules. Ph.D.in biological science (Pharmacology preferred)or equivalent work experience required, alongwith at least 3-5 years in drug/receptor inter-actions. The preferred candidate will also haveformal training in receptor pharmacology andreceptor isolation.We offer an attractive salary plus comprehen-sive benefits. For confidential consideration,please send your resume with salary history to:G.D. Searle & Co., Dept. HY4, 4901 SearleParkway, Skokie, IL 60077. Equal OpportunityEmployer M/F/H/V.

I

S j

Candidates should have a recent Ph.D. in Pharmacology,Biochemistry, Cell Biology or related field with 1-3 yearsrelevant postdoctoral experience. Our laboratory is cur-rently involved in the search for new chemotherapeuticstrategies for the treatment of malaria. We pioneered workin the area of inhibition of polyamine biosynthesis for thetreatment of parasitic diseases. We are also interested inresearch in the areas of nucleoside/nucleotide meta-bolism cytoadherence, membrane biochemistry andglycoprotein biosynthesis. This is an opportunity to workon basic research problems in an exciting, goal orientedenvironment. Work includes cell culture, enzymology,HPLC and other basic biochemical/pharmacologicaltechniques.We offer excellent compensation, comprehensivebenefits, and relocation assistance. Please send your cur-riculum vitae with bibliography, salary expectations, andnames of three references in confidence to:

Job Code AJBPersonnel ServInces Manager

Merrell DowMERRELL DOW

RESEARCH INSTITUTE2110 E. Galbraith RoadCincinnati, Ohio 45215

US Citizenship or Permanent Visa RequiredAn Equal Opportunity EmpkwymM/F/HNv

Smith Kline & French Laboratories, a leader in pharmaceutical research, is seek-ing an experienced scientist with a background in protein chemistry or protein bio-chemistry for its Drug Metabolism Unit located in suburban Philadelphia.The successful candidate will:* apply multidisciplinary techniques to study disposition of therapeutic proteins to

support drug development and diswDvery.* study protein and protein-ligand interactions involving specific disposition

process.* study the intrinsic and extrinsic factors governing the pharmacokinetics and

metabolism of proteins of therapeutic interest.* Plan and develop analtical approach as needed to conduct these studies.Candidates are required to have:* Ph.D. in protein chemistry or potein biochemistry or related areas with strong

background in protein chemistry.* experience in bioanalytical methods development required; e.g., immunoassays,

HPLC and enzymatic assays.* experience in modifying protein/peptide molecules with specific properties.* familiarity with general analytical tools applicable in protein biochemistry re-

quired; e.g., electrophoresis/isoledrofocusing, immunoblotting, protein columnchromatography, etc.

* knowledge in enzyme kinetics.* demonstrated ability to integrate and apply multidisciplinary approaches in re-

search problems.* knowledge in drug metabolism and pharmacokinetics preferred.We offer an excellent compensation, benefits and relocation package as well as op-portunities for personal and profesional growth. For confidential review, pleaseforward your C.V. and names of three references to: Marianne J. Shandy, Man-ager, Personnel Relations, J0003, Smith Kline & French Laboratories, Research &Development, P.O. Box 1539, King of Prussia, PA 19406-0939. We are an EqualOpportunity Employer, M/F/H/V.

0 lIlfililZLIlil

RESEARCH SCIENTISTSIntegrted DNA Technologes, Inc. is seeking qualifiedscientists to conduct research in exciting new areas of clinicaldiagnostics and therapeutics. These positions will provide anopportunity for original research and leadership within a growingorganization.All positions require a Ph.D. degree; relevant postdoctoral orindustrial experience would be desirable.

MOLECULAR BIOLOGIST: Experience in recombinantDNA technology and DNA probe hybridization systems, with somebackground in clinical or diagnostic microbiolgy.

VIROLOGIST: Experience in clinically relevant virology,recombinant DNA technology, and tissue culture; for research onantiviral therapeutics.

MOLECULAR GENETICIST: Experience in molecular biol-ogy and DNA hybridization technology as related to cancer/oncology or genetic disorders.

BIOORGANIC CHEMIST: Experience in nucleic acid, nucle-oside or backbone modification, and affinity/solid support chemis-try.

In addition to a stimulating scientific environment, we offer acompetitive compensation/benefit package and relocation assist-ance. IDT is located in an attractive midwestem community and isin close proximity to a major university and medical schoolcomplex. Please send a resume and descrption of researchexperience to: Peornnel, Inteated DNA Technologbs, Inc.,Tech hnnovatlen Centr, Oakdab Campus, kea City, IA 52242.

RATED

'OLOGIES, INC.

I D T INTEG]DNA

*_________ TECHW

WALTHER ONCOLOGY CENTERFACULTY AND

POSTDOCTORAL POSITIONS

MOLECULAR BIOLOGYTHE WALTHER ONCOLOGY CENTER at the INDIANA UNIVERSI-TY SCHOOL OF MEDICINE, is seeking motivated and productivecandidates to pursue original basic research in the areas of:

Gene transfer (transfection, retroviral infection, trans-genic mice), gene cloning, regulation of gene expres-sion (including oncogenes), especially as they relate togrowth and differentiation factors and their receptors,and genetic mechanisms of multi-drug resistance tochemotherapeutic agents.

Faculty (tenure- and non-tenure-track) and post-doctoral positions areavailable for candidates with PhD, MD and MD/PhD degrees. Primaryappointments will be in clinical and/or basic science departmentswithin the Medical School. Laboratory space will be in the new ClinicalResearch Building.

Interested candidates should send their C.V., publication list, researchgoals and the names and addresses of at least three references to:

Hal E. Broxmeyer, PhDProfessor of Medicine,Microbiology and ImmunolegyScientific Dlrector, The Walther Oncology CenterIndiana University School oIMedicineClinical Building, Rm 379541 Clinical DriveIndianapolis, Indiana 46223

Indiana University is an Affirmative Action/Equal Opportunity Employer

SENIOR SCIENTISTS -MOLECULAR BIOLOGY

THE LISTER HILL NATIONAL CENTER FOR BIOMEDICALCOMMUNICATIONS, the research division of the NationalLibrary of Medicine located at the National Institutes ofHealth in Bethesda, Maryland, is seeking qualified in-dividuals for a Senior Scientist position in its BiotechnologyInformation program. The candidate is expected to establishand conduct a research program in molecular biology com-puting which may include, but is not limited to, prediction ofstructural or biological function from sequence data, com-parative analyses of physical and genetic maps, patternrecognition in sequence data, or evolution of gene se-quences. Computing facilities include twenty Sun worksta-tions and servers, DEC Vax 111780s, IBM mainframes, a net-work link to a Cray S-MP at the National Cancer Institute, anddirect Arpanet access. Programming staff support is alsoavailable.Applicants must have a Ph.D. in molecular biology or arelated field and a publication record in the above researchareas. Appointment is for a one to two-year period, exten-dable to four years. Salary range is $40,000 to $65,000 depen-ding upon experience.Send curriculum vitae and the names of three references to:

Dennis Benson, Ph.D.Lister Hill National Center for

Biomedical CommunicationsNational Library of MedicineNational Institutes of Health, Public Health Service8600 Rockville Pike, Bethesda, MD 20894For further information call:Ms. Yvonne Reid (301) 496-4441NIH IS AN EQUAL OPPORTUNITY EMPLOYER

Senior ScientistGeneticist/Cell Biologist, Ph.D., postdoctoral experience pre-ferred, to join our effort in producing improved crop plants.Candidate should be a well-trained plant biologist with an inter-est in the problems of agriculture and the ability to contribute tothe solution of these problems. Background in agriculturalaspects of plant science desirable, as is experience with plant celland tissue culture, transformation, and the analysis of transgenicplants.

Zoecon Research Institute has been a leader in innovative agri-cultural research for more than 15 years. The institute hasestablished research programs in herbicide design, plant bio-technology, insect physiology/biochemistry and chemistry.Research in plant biotechnology supports the plant breedingefforts atNorthrup King Seeds, Rogers Brothers Seeds, and otherSandoz seed companies. Our research environment encouragesinteraction with other scientists throughout the world.

To apply for the position, please send a letter describing yourinterests, a curriculum vitae and the names of three references to:

SANDOZ CROPPROTECTION CORPORATIONZoecon Research InstituteHuman Resources Department975 California AvenuePalo Alto, CA 94304

AA/E0E /

CELL BIOLOGY OPPORTUNITIESMARKETING * R&D

Molecular biology, tissue culture, cell biolo and immunology- all areareas ofinterest in our expanding circl ofscienc Formd in 1983froma merger of Bethesda Research Laboratores (BRL) and the GIBCOLaboratores Division of the Dexter Corporation, Life Technologiesis a preeminent and innovative leader in the expanding life sciensresearch community, the bioprocessing marketing anddthebiotechnologyindustry.We have now made a major commitment to expand ourproduct offering in cellular biology. We are looking for thefollowing managers with industry experience and a workingknowledge of cell growth factors, hormones and receptors.membrane reagents, oncoprotein reagents. second messen-ger and related reagents.

MARKETING MANAGERCreate strategic plan and forecast for Cell Biology business.Initially serve as Marketing ManagerAND Product Manageruntil business supports additional staff A record of successwith 3+ years relevant marketing and/or product manage-ment experience required. MBA preferred.

DIRECTOR, CELL BIOLOGY R&DOrganize, staff and manage R&D function with capacity topropose, design and develop new products or improveexisting products. We seek a Ph.D. with post doctoraltraining. Business experience with exposure to Sales/Marketing. Operations and other business functionsessential.Interested candidates should send resume, in confidence, to:

Director of Human ResourcesLife Technologies, Inc.8717 Grovemont CircleP. 0. Box 6009Gaithersburg, MD 20877An equal opportunity emplover. M/F/V/H

4 ~ResearchOppoitntes

The Plant Molecular Biology Group of MonsantoCompany is seeking outstanding scientists to expand ourresearch efforts in several areas of plant biology. Positionsare available for:

Senior Scientist with a Ph.D. in Molecular Biology,Biochemistry or Plant Paffitogy, and a significant recordof accomplishment. Post Doctoral experience isdesirable.Research Assistants and Associates with a BSorMS in Biochemistry, Molecular Biology or related fields.Experience in protein purification, gene isolation or planttissue culture is especially desired.Post Doctoral Research Assocites in MolecularBiogy, Biochemistry, Virology, Plant Pathology or PlantTissue Culture/Transformation.Monsanto offers an excellent salary and benefits packageand stimulating work environment Please send yourcurriculum vitae, a summary of your research interests,and 3 letters of reference to: MONSANTO COMPANY;John Bussen; Department BB5BO-AG; 700Chestilield Village Pwlway, St. Louis, MO 63198.Equal Opportunity Employer M/F/H/V.

4Monsanto)

PROJECTMANAGERIf you're interested in a career with a leading healthcare company, why not begin your search with acompany respected the world-over for its profoundcommitment to care, to quality, and to innovation?Baxter Healthcare Corporation has demonstratedthat commitment for over 30 years.Currently, our Baxter Hyland Division is seeking aqualified individual to plan and implement programsto improve quality and yield of blood-derived thera-peutic proteins; coordinate and implement projectsfrom inception to completion; conduct feasibilitystudies; organize scale-up activities; and providesupport for transfer of technology into production.A technical degree or equivalent experience (Ph.D.in Protein Chemistry or an M.S. with 7+ years proteinpurification experience desirable); strong super-visory, communication, and project organization ex-perience; and knowledge of standard lab equipment,production equipment and statistical proceduresrequired.Baxter offers a fast-paced, stimulating work environ-ment, attractive benefit and compensation plans,and the opportunity to work for a world-class leaderin the health care industry. For consideration, pleasesend a current resume with salary history to: Ms.Vickie Thrasher, Baxter Hyland Division, 4501 WColorado Blvd., Los Angeles, CA 90039. PRINCI-PALS ONLY, PLEASE. Equal Opportunity Employer.

Hyland Division

Baxter

__m I

IE:jIl

f

NPOSITIONS OPEN

RFSEARCH ASSOCIATEFull-time position available 1 April 1988 for scientist

with Ph.D. or M.S., and rs experence in ekctronmncroscop to study mechanisms ofmlin degenaionin cdl culture and to supvise routn peraon ofbo Contact: Dr-rsAMisic, DesA.

manat=f NeUrOg, St. LI;s Ui,36Avenue, St Louis, MO 63110. Telpone: 314-577-6082.

RESERCH ASSOCIATEIhe Center for Lascer and Applied Technolgy, Char-

lote Mcmorial Hospital and Medical Center invitesappikations for a full-time resarch assoat position.The position will involve rsach in cardiovasulr appli-cations of lasers. Individuals appi should have previ-ous experience in small anial cardiac surgry, cardiac

catheizato cardiopulmonary bypass fsion ofcanines, and the use oflasers. A 2- or 4-year degree in ardated fidd is also required.

Intersted applicants should submit curriculum vitaeand lettes of recommendation by 15 April 1988 to:

Geow TatsisHememan Me Researh Labor

P.O. Box 32861Charlot, NC 28232

Equd 0Op ity Employer

Imediate opening. RESERCH ASSOCIATE-Ph.D. with exprince in protein purification, HPLC,immunochemical nmthods, monoonal antibody, and soforth. Salary $25,000 to $30,000. Send r&sumi to: AdelA. Yunis, M.D, De of Mediine (RL-38),University of Miami Sool o Medine, P.O. Box016960, Mimi, FL 33101.

An Equal Oppo0tuity Emplyment

RESEARCH ASSOCIATEPOSTDOCTORAL

Position now opCe to study the role ofsp protin-ases involved in mammalia phasis is onthe nchanism of action and mgulaion of thetp ro-sin-acrosin enzyme system. This positon will m forindepndnt rescarch as well as rainin in an area ofinterest to the academic, mdical and pham tical

community. Applicants with interest in cell/molecular

biology, biochemical, or immunological aspects of the

g

are ouraged to aply. Send curriculum vitae,Zng cizenship status, lie names ofthree referncs

and research and career goals to:

Kenneth L.Pakoski, Wh), Department ofObstet-rics and Gyneolo, Wahn University, 4911Barnes Hpil a, St. Louis, MO 63110. AnEqual OppwrftityL4firmatvActon Employer.

RESEARbCH TECICIANS-Applications areimied for two full-time technicians in uatic research.OnC poition is availabk to assist in expeamental studiesof miog and nutrients/herbivores in marinc andfrehwater ecoysem. A second position is available toassit in studies ofnutrient and gieffts on freshwatcrphytoplankton communities. The positions are assuredforyatlast 2 years. Experience with agae and/or aquaticch sry, and a B.S. degre are preferred. For informa-tion, contact: Dr. JoAnn BurOhoder,D t ofBotany, Box 7612, North Carolina UStateU(NCSU), Raligh, NC 27695. Tephone:

2726 or 919-7a7-2727. NCSUis AffitAction/Equa Opotunity Employer.

REBSEARbCH TOXICOLOGIST with interest inbiohdemical mechanisms of chemical tonxacty and carci-nognicity to kad original research projects. Ph.D. inbiochemistry, toxicology, or a related area, and at kast 2years of podoc research perience in drug ordcmial carcnoge metabolism required Experiene isrequiredinthedconofDNA adducts using radioact-

tv arnopes and by 32P-posabing,pues invlving radioisotps chmcl analysis by

SMRandmass pemy, chromatographic tech-

niques induding HPLC and GC, operation of a super-

cond spe r. Salary $46,000 peryear.

Forty hours per wee. Contact: The Job Servie at 516

North Mangum Street, Durham, NC 27701, or thejob Serice t you. Refcr to Job Order NumberNC 7102163.

RESEARCH ASSOCIATE OFMICROBIOLOGY AND IMMUUNOLOGY

Research associate: Minimum r ts: Ph.D.,M.D., or equivalnt, with knwledge of ceIllar and/ormolcular immunology to work on project conceni gthe s of chronic inflamnmtory diseases. An-

en S20,000 and $28,000,dpding onan quafto. Send rourn to: Mr. K E.

Id,vUivrk of Illois at Chicago, Depr-mca of noiagy, E-703 AISA,835 South Wolott, IL 60612. The Uxireis anAf ai mi/EqA p Exlyer.

MOLECUIAR GENETICS/PATHOLOGY LABORATORY

UNIVERSITY OF NORTH CAROLINACHAPEL HILL, NORTH CAROLINA

(Under the directi ofDrs. Olir Smithia and Nobuyo Maeda)

RESEARCH TECHNICIAN m to ppat intesarch leading to producto of tawnsg c animals by

injection ofembryonics cels intobDancss. Overallresearch is aimed at modifying specific genes m a predict-able way with a view to gene therapy and the geneaionof animal models of human genetic diseases. B.S. inbiological scince is required. M.S. in biological scicnceand at last 1 year of expeerince with microuniction andembryo tr , and in mouse breding rred.

Ihlis position is open 1 Junc 1988 atThe Univesity ofNorth Caolina at Chapel Hil, but is available immedi-ately if the successful candidatc is willing to begin workat the University of Wiconsin at Madison. Startsalry c s with background and expence.Salary range: $19,944 to $30,264. For an appLication,contact Ms Carolyn Van Sant at:

UNC EmplymCB# 1040, l11 PettigEw HailChapel Hill, NC 27591040Telepoe: 919-962-2991

Equa OppoutnixylApffwwuaaivAcion Explyer

Professional Carecr Oortunities at our 600+ bedtertiary care affiliate of Moinell Universiredical Col-lege. ECHNOLOGISTMOLEC IMMU-NOLOGY: Skiled in molecular bioklic techniqucs andtissue cukure work quwired. Minimum: 3 to 5 years ofexperience in molecular biolog and immunokgy. R1E-SEARCH AND ASS1SI&4T-NEPHKOTOGY:Laboratry or kidney discase and hypetnsion Mini-mum: 1 year of research experience essential, p yinvolving RIA and smalla surgery. B.S. degee orequivalent Comprehensive salary and bencfits pacage.Reslpond by rdsun, or call: Personnl D n,North Share Univest Hospital, 300 CommunityDrive, Manas NY 11030. Teqpoae 516-562-4690.Ax Equal p E e.

VISrTNG ASSISTANT PROFESSOROF BIOLOGY

Hope Colege is seeking to fill the positim of visitingasstnt profesor of biology. This appointmnt will befor a 2-year period, with the possibility of renewal for anadditional 2 year. Thc individual selected for this posi-tion will be expcted to teach general microbioyadvanced micobio, and p ae in the introduc-tory program for biogy maors. The individual will bcstrongly eouragd to take advantage of the opportuni-ty to partipate in onc ofthe ongoing research prgrin the de . The Biology biculty has a strongrecord ofactiityin externall fundedrecA list ofresearch oppotunities provided upon requestHopecolege is ad is Chrisin co-educa-

tional, residential liberal arts e affiliated with theReformed Church in America HopcCollege has main-tained a strong tradition in sci that involves bothtecigandrsarch. Aopplcatiomfim women and me-n nd .Aypm ar9artiulary enoured

Qualified applicants should arrange to have curriculumvitae, transcipts, a statement of taching competencesand indication ofresearch orientation, andthree tt ofrcm ndation forwarded as soon as possibk to:

Dr. James M. Genile, ChairmanBiology DprtmnHopc~ Coilg

Iplicaions will be acccpted until this position is

SCIENCE WRITER-Manning, Selvage & Lee, amajor New York City public relations agency producingmaterial for science wnters and broadcasters, is currentliylooking for an eperienced (1 to 3 years) science writer towork on a leading phamaceutical company account.Ph.D. or similar advanced decgre required. Candidatemust be capable ofwriting for lay audiences, and shouldhave epenene in cental nervous sytne and cardiovas-cular diseases and diabete.Send ktter, rtsumi, and salary history to:

Mnnin& kkei e&Lee79 Madio AD _BentHR

New tori, NY 10016

ANIMAL AND PIANT HEALTHINSPECIION SERVICE

UN1TED STATES DEPARTMET OFAGRICULTURE

Innovativc SCIENTISTS with good research writingskills and advanced education or work expenc inbioe dy are bein rcred for svcral newly

created pso with the Biolopcal Asxsment Sup-port StS Biot?cnlgy Permit UJnit.This challng opportunity will involvc the technical

assessment and1valuation of submissions for release tothenv nd transport of eically

Ies iwfividuaFs will guide and de p pdicconcerning the egulation df se gansms as wel astrvld uo the U.S. incng with the scentific

Sil candidates iEveavacd dcation orwork experience in one or more of the following areas:moAlcular biology, microbiology, moecular genetics orplant breeding and genetics. Salary range starting at$27,716 to $43,181 per year. Interested individuals call:202-382-1364 to request a copy of announcementnumber W-411A-88 fur application requimcnts.USDA i an Equal Opotuty Employer.

TUMOR BIOLOGISTApplications are invited for a tenure-track position at

the assistant profiessor evelinthe Head and NeckTumorBiolgy Program at Eastem Virginia Medical SchooLThe successful candidate will have a joint appointment inthe Deparqxn ofMicrobiology/Immunogy and 0oaryngl gy-Head and Ned Su . An ND. and/orPh. and postc ral experience are required. Investi-gators with reseah imerets in molecular and cellularaspec of cancer are eurag to apply. Applicationsfiom indiduals th r expen e in had andneck oncobgy, oncnes, in vivo models, steroid and

Pobhorumoncsreceptors, and cytogmentics areFtwccmd. Intmsed candidate sxxld send

their curriculum vitae, a brief descipton of fitureresearch intsts, and the names of three refrenes to:Dr. Kenneth D. Somcrs, Chairman, Search Comit-tee, Department of Microbiology andImmEastern Virga Medical School, P.O. Box 198,Norflk VA23501.

VERTEBRATE PHYSIOLOGISTApplications are invited for a tenure-track assisant

profesorshipinthe Department of Zoology, UniversityofToronto,beinning 1July 1988 or thereafter. We areseeking an outsding and innovaivc scentLst who hasrecently received his/her Ph.D. degree, but applictonsfrom more established inveastitors will be considedThc successful candidate wil e cxpcted to establish avigrous, i et rarch pam, preferably inenvironmentally related vertebrate pysioogy andtcachat underraute and grdate levels. Salary, currntybetween $t30,000 and $51,000 for an assitnt professor,will be comm uate ith expericic and quiions.By 15 April 1988- applicants should send a currentcurriculum vitae, a description of their fure researchplns, and a list of the names and addresses of at leastthree eferes. If the wish, applicants may arrange withtheir referees to send ktters on their behal. Send mate-als to:Dr. John Mac,Physi,t Sa ,

Depar_ment of Zodoloy, Univrsity of Toronto, 25St, To , Ontario 15S lAl, Csnad

In acrda with Cana Im r rt*hisaver sm ni diree i thean citem and landed In acrdance with th

Eq Poy of the Unirty Of Torot,inaitedf aquaed wwomn and men.

SCIENCE., VOL. 239

POSITIONS OPEN POSITIONS OPEN

DEVELOPMENTAL NEUROBIOLOGY

The Research Institute of the Hospital forSick Children, one of the largest and mostactive of its kind in the world, is seeking anoutstanding scientist with a Ph.D. or M.D. tocarry out basic research and developmentalneurobiology as related to Sudden InfantDeath Syndrome (SIDS).

The appointee will be expected to collabo-rate with an established group studyingSIDS and will also develop his/her own re-search program. The appointment will be ata rank equivalent to assistant or associateprofessor.

Send curriculum vitae, a brief description ofresearch interests and the names of 3 refer-ences before April 15, 1988 to: Dr. Barry T.Smith, The Research Institute.

1 1< | 555 University Avenue, Toronto, Ontario M5G IX8

THE HOSPITALFOR SICK CHILDREN

Bio-Rad Laboratones is a worldwide leader in thefields of clinical diagnostics, chemical separationsand analytical instrumentation. Our Clinical Diag-nostics Division has outstanding opportunities forexperienced, goal-oriented research scientists toassume leadership roles in developing diagnosticreagent systems for the 1990s.

MicrobiologyThis position requires experience in the isolation,characterization and detection of infectious diseaseantigens in clinical specimens. An MS/PhD inMicrobiology or equivalent experience is required.Dept. #271-0318S.

Instrumentation EngineeringFive or more years experience as a senior projectengineer coordinating both mechanical and elec-tronic engineering of instruments. Demonstratedability to work in a multidisciplinary environment.Strong communication skills are required. Dept.#293-0318S.

Immunoassay DevelopmentThese positions require a strong background in thedevelopment of commercial immunoassays and anMS or PhD in biological sciences or chemistry.Experience in automated immunoassay is desirable.Good communication, leadership and problem solv-ing skills are essential. Dept. #292-0318S.

Organic ChemistThe position will work with an interdisciplinary teamin the development of novel organic compounds foruse in immunoassays. The position requires a PhDin chemistry with a strong background in organicsynthesis. Dept. #288-0318S.

Sr. R&D ChemistThis position will develop and evaluate HPLCmethods and instrumentation for drug analysis. Anadvanced degree in analytical or clinical chemistryis desirable plus experience in chromatography,instrument design, electronics and computers. Dept.#294-0318S.Be part of the team in our new facilitiesoverlooking the SF Bay in Hercules,California.For consideration, please submit resume, indicatingappropriate department, to Bio-Rad Laboratories,Human Resources, 1000 Alfred Nobel Drive,Hercules, CA 94547. EOE.

- 9Z:: Bio-Rad Laboratories

IkPdoctor4 ScienlistGenentech, Inc., a leader in the field of biotechnology,is currendy seeking a Postdoctoral Scientist. In this posi-tion, you will be involed in the development of in vitroand in vivo cellular and animal models which can beused to predict the efficacy of protein or peptide immu-nobiotherapeutics.Requirements include experience in tissue culture andin the preparation and handling of human blood leuk-ocytes. Experience in the development and use of immu-noassays and in animal handling is desirable.Genentech, Inc. offers an excellent salary and benefitspackage, coupled with the opportunity to make a signifi-cant contribution to our organization. Please sendresume to: George Cianciolo, Scientist, Genentech, Inc.,460 Point San Bruno Blvd., South San Francisco, CA94080. An equal opportunity employer.

Genentech, Inc.3&mmaRh,O noo

M-

0---

a

m

GRADUATE TRAINING

SECURITY POLICY STUDIES: Thc Program onInternational Pcacc and Socurity at Carngic MellonUniversity secks a PTOC T FELLOW toperform a serics of assessments ofadvanced technologiescritical tO military modenization. Applicats shouldhave Ph.D. in ectkical or computcr egineerng orphysics. Appl to: Gnger M n or Bnoit Morel,LX mmbf and-PuofiqPORCY, Came-gieMelon U J,P PA 152i3. Tel-phone: 412-268-2672.

VETERINARY PATHOLOGISTThe Laboratory ofBiochemical and Gentic Toxicolo-

gy of the Wadsworth Center for Laboratories and Re-search invites applications for a position of vetrinarypathlogist. The candidate must possess a D.VJM. de-gree or equivaknt, and be Board-eLigible or ccrtified bythe American CoLke of Verinary Pathologists. Theindividual is expectd elp a sf-sdlcted, indepen-dent rescarch program compatibk with the broad gencr-al interests ofthe Center, and to conduct service patholo-gy evaluations of a wide range of toxicology and otheranimal studics. Research collaborations with WadsworthCenter scientists, who arc engaged in all aspects ofbiomedical research, are so enurage R chtime commitment will be approximae 70%, and ser-vice time commitment will be 30%. There are alsoopportunities tO tach and recruit graduate studes inthe recenty initiated School of Public Helth Sciences, ajoint venture betwen the Wadsworth Center and theState Univcrsity ofNew York at Albany. Thc grade kvel,academic ranking, and salary will be commensurate withprofessional cxperience. Send curriclum vitac and throeltrs of reference, within 1 month, to: Dr. LaurenceKaminaky Wadsworth Ccenter for aboratories andResearc<h,P.O. Box 509, Albany, NY 12201.

AWARDSThe Charles A. Dana Foundation announces that the,

3rd annual CHARLES A. DANA AWARDS FORPIONEERING ACEVEMENTS IN HEALTHAND HIGHER EDUCATION will be made in No-vember 1988. These awards, which include an honorari-um of $50,000, rcognize oustanding contributions inhealth promotion/disease preventon and, se ly, tothe improvement of undrgraduate eduction. Nomina-tions mustbe posmaredby 1 June 1988. For fiuthcrinfrmation, contact: Joseph P. Wells, The Charle A.Dana Foundation, 150 East 52nd Street, Box S, NewYork, NY 10022. Tdlphone: 212-223-4040.

GRADUATE PROGRAM

Ph.D. degrees in aquatic ecology, chizing theefficts of nutrients and light on phytoplanmo in NorthCarolina lakes. Two -and73-year graduate RESERCHASSISTANTSHIPS are availabletOhighly qualifiedstudents, at $8,400 to $10,000 pe year. For informa-tion, contact: Dr. JoAnn Burkholder, Department ofBotany, Box 7612, North Carolina State U(NCSU), Raleigh, NC 27695. Teephone:2726, and Dr. Val Smith, Dep t of BioloyUnivers of North Carolina (UNC), Chapel HlNC 27599. Tephone: 919-962-6930. NCSU andUNC are E Opptunity Emplyer.

WORKSHOPWORKSHOP ON

BIOLOGICAL DATA FORPHARMACOINETIC MODELING

AND RISK ASSESSMENT23 to 25 MAY 1988

Sponsored by the ILSI Risk Scicnce Institute and theU.S. Environmental Protection Agency, held at GreatSmokies Hilton, Asheville, NC. Workshop will provideinsights and guidance to risk assessors with respect to thergor of anaysis, focus on makin% the uncertainties inmoedeling more explict, commumcatc to biologist thevalue ofpharmacokinei models and the kinds of dataneeded, and identify resarch/data needs for usc ofpharmacokinctic models in risk assessment. The meetingwill bc limited to approximatcly 100 particina'ts.

Detais and apicafim forms frcon: s1 ieSd;|=Eatem Re i Grup 6Whiore Stret, Arling-ti,MA 02174. Tdqn 617-648-78107809.

1462

GRADUATE TRAININGIN NEUROSCIENCE

The De of Physiology and Biophysics atHahnemann University has graduate stipends availableto support stdnts pursuig a Ph.D. degree in physiolo-gy beginning in September 1988.The dpartmeLt has patiular research strengths in

neurophysiobgy, neuropharmacoloy, and neuroanato-my. Specific areas include: extrahc~iamic actons ofsex steroids (Sheri S. Smi), alia fnction(Jay cb corx functio, neural net-work simulaions and alcohol (John L Chapin), andcentral miooamn sysm, cpilep and drugs ofabuse(Barry D. Watehouse).Thc program is open to students with a B.S. or M.D.

degree. Further inforation and application forms arcavailable from: Dr. Joseph Torres, OfPhysNiob ThyBiq, M.S.40, hnUnivrsity, Broad and Vime, Philadelphia, PA19102-1192. AffirtiaemAaion Expobyer.

TRAINING PROGRAM

REPIODUCTIVE BIOLOGY TRAININGPIROGRAM: Pre- and postdcoral posiions are avail-able at the Oregon Health ScSinces University (OHSU)and at the Ovegon Primate Research Center that aresuorted by a NICHD training grant beginning 1 July1 . Studnts may enroll in tIe graduate programthrugh the Departes of Physiolgy or Cell BilogSyand Ana , OHSU and ma participate in intdisci-plinary grduate pro$rams in neurobiology, or cell andmolecular biology. Eighteen faculty members offer multi-discpinary ning inern doriolg (C. L.RrV.B. Cr w,M.J.KeI,A.J. Lcwy, S. R

Ojeda, 0. LR ); biolgy o the gonads andreproductive tract (R. Brenner, A. Masar, R LStma&r)- gamete biology and ferilization (D. D. Hoe-, D. P. Wolf); pregnancy and fetal development a.

IL Bisone_t J. A. Resko); cellar mechanisms ofhom"one action (M. IL Melner, C. B. Rowlli); sexualbehavior (C. H. Phoenix); and rep ve toxicogy(D. L Hess).Applcant must meet NRSA, U.S. idzenship and

residency requirements. Predoctoral candidates can re-ceive infonraion on the grduate program from theaddress below. Postdoor candidates should send aleJtr of imtst, curriculm vitae, and names of threcreferences to: John A. Resko, Ph.D. Cairman, De-

of Orcaon Health ScencesUniverdty, Po OR 97201. OHSU is an EqulOpp orqity Exq*er.

FELLOWSHIPS

HARVARD SCHOOL OFPUBLIC HEALTH

INTEBRDISCIPIINARY PROGRAMSIN HTH

POSTDOC`ORAL FELOWSHIPS

Te Program in Envirmnt Healt and PublicPolicy inv applications from promising graduates of

advanced degrec programs in thc nantral or social sci-ences. The program focuses on thc scientific and analyi-cal foundations for cnvironnmntal decisions. In addition

to individual research, fllows are cncour-ag to colle with each other and fculty memberson projects of mutual intarest. A group project mightconsider, for example, the effict ofscientific uncertatieson enironmna decisions.

Felows will be appointed for a term of 1 year, startingSeptember 1988. Award may be rcnewed. lication

dedline: 15 April 1988. Decisions announced m May.For information, write to:

Professor DonaldF. HonigHarvard School of Public Heth

665 Huntington AvenueBoton, MA 02115

Telhone: 617-732-1258

TOXICOLOGY UPDATE 1988CURRENT CONCEPTS IN

REPRODUCTIVE TOXICOLOGY6 to 8 JUNE 1988

This coursc will examine the principles necessay toundertand how chemicals intcract with the rroductivesystem and the consequences of such intcractions. Thekctures will providc a general overview of toxicologicpinciples and ofmale and female reproductive physiolo-gy. DIrcoS: M. A. Trush and T. W.Keler. Forfrther information contact: Dr. J e Corn, TheJohns Hopins School ofH and Pub Heal,615 North Wolfe Stret,'x wc, MD 21205.Telepone: 301-955-2609.

PROGRAMCAREER CHANGE OPPORTUNITY

This uniquc program offers the candidate with ancamed doctorate in the sciences the opportunity toobtain a doctor of optometry (O.D.).degre in twocalendar years. Emplomnt opportunitics exist in pri-vat raxce, industry, education, and research. Contact:

D. Program Director, Admissios Office,The Ncw Englnd Colkge of Optometry, Room 14,424 Beaon Street, Boston, MA 02115.

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIP INCLINICAL LABORATORY MUMUNOLOGYApplications are invted for a 2-year fellowship in

clinical laboratory immunology at North Carolina Mle-morial H'ital (NCMH) and the University of NorthCamlina (UNC). Fellowship provides residency-typetraining in laboratory immunoiogy through laboratoryexperience, conferences, and rescarch. Send curriculumvite and three kttrs of reference before 20 April 1988to: Dr. James D. Folds, PhD., Dirctor, ClinialMicrobiology-Immunology Room1035 PST, North Carolina Memorial Hospial, Cha-pel Hill, NC 27514. The UNCaWCMHr an EqualOp AuitielAffivmaaiveAain Employer.POSIDOCTRAL FELLOWSHIPS (two) atThe

University of Chicago to conduct research in (a) evolu-bology and(b) genetics. Both fellows will also

ide half-time assistnce in the design, coordinationand teaching of introductory biology labs. Twelve-monh position beginning 1 September 1988, renewabkfor 1 year. Salary:$18,0s00. Submit curriculum vitac,three letters ofrefnce, and a statement which discussesyour teacling interests and identifies a University ofChicago faculty sponsor for your proposed research.Applications should bc sent before 11 April 1988 to:Postdocora Search Committee, Dr. Ro Pot-ter, Biogical Sciences Collete Division, 940 East57 S , Chkago, IL 60637. Equl Opp0unityl

MARKETPLACE

ers SeMc8e;araSCIENCE, VOL. 239

POSITIONS OPEN COURSE

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