(Continuedfirom page 804)

606 pp., illus. $109. Institute of Physics ConferenceSeries, no. 86.

Quldditles. An Intermittently Philosophical Dic-tionary. W. V. Quine. Belknap (Harvard UniversityPress), Cambridge, MA, 1987. xii, 249 pp. $20.Radar Days. E. G. Bowen. Hilger, Bristol, U.K.,

1987 (U.S. distributor, Taylor and Francis, Philadel-phia). xiv, 231 pp., illus. $28.Radiocarbon Dating. An Archaeological Perspective.

R. E. Taylor. Academic Press, Orlando, FL, 1987.xii, 212 pp., illus. $39.50.A Reference Catalogue and Atlas of Galactic

Novae. Hilmar W. Duerbeck. Reidel, Dordrecht, 1987(U.S. distributor, Kluwer, Norwell, MA). 212 pp., illus.$48. Reprinted from Space Science Review, vol. 45, nos.

1-2.Reflections on Kurt G6del. Hao Wang. Bradford

(MIT Press), Cambridge, MA, 1987. xxvi, 336 pp., illus.$25.Right Whales. Past and Present Status. Robert L.

Brownell, Jr., Peter B. Best, and John H. Prescott, Eds.International Whaling Commission, Cambridge, U.K.,1986. viii, 289 pp., illus. $60. Reports of the Interna-tional Whaling Commission, Special Issue 10. From a

workshop, Boston, MA, June 1983.Scanning Electron Microscopy and X-Ray Micro-

analysis. GrahamLawes. Published forAnalyticalChem-istry by Open Leaning, London, by Wiley, New York,1987. xviii, 103 pp., lus. Paper, $21.95.Seismic Tomography. With A plications in Global

Seismology and Exploration Geophysics. Guust Nolet,Ed. Reidel, Dordrecht, 1987 (U.S. distributor, Kluwer,Norwell, MA). x, 386 pp., illus. $68; paper, $38.Seismology and Exploration Geophysics.

Setting Limits. Medical Goals in an Aging Society.Daniel Callahan. Simon and Schuster, New York, 1987.256 pp. $18.95.The Stages of Human Evolution. Human and

Cultural Origins. C. Loring Brace. 3rd ed. Prentice-Hall,Englewood Cliffs, NJ, 1988. vi, 154 pp., illus. Paper,$14.

Statistical Analysis with Missing Data. RoderickJ. A. Little and Donald B. Rubin. Wiley, New York,1987. xvi, 278 pp., illus. $34.95. Wiley Series in Proba-bility and Mathematical Statistics.Theory and Models in Vegetation Science. I. C.

Prentice and E. van der Maarel, Eds. Junk, Dordrecht,1987 (U.S. distributor, Kluwer, Norwell, MA). 223 pp.,illus. $122.50. Advances in Vegetation Science, 8. Froma symposium. Uppsala, Sweden, July 1985. Reprintedfrom Vegetati, voI. 69.Thermodynamic Properties of Helium. V. V. Sy-

chev et al. Theodore B. Selover, Jr., English-languageedition editor. Hemisphere (Harper and Row), NewYork, 1987. xvi, 316 pp., illus. $120. National StandardReference Qata Service of the USSR, vol. 1. Translatedfrom the Russian edition (Moscow, 1984). The firstvolume of a series in which volumes on other substances,including methane, ethane, oxygen, and ethylene are alsonow available.Thermophysical Properties of Freons. Methane

Series. V. V. Altunin a al. Theodore B. Selover, Jr.,Enghsh-language edition editor. Hemisphere (Harperand ow. New York, 1987. Part 1, xxxiv, 200 pp., illus.$120. vol. 8. Translated from the Russian edition (Mos-cow, 1980). Part 2, xxxvi, 243 pp., illus. $120. Translat-ed from the Russian edition (Moscow, 1985). NationalStandard Reference Data Service of the USSR, vols. 8and 9.Thin-Layer Chromatography with Flame Ioniza-

tion Detection. Mojmir Ranny. Reidel, Dordrecht,1987 (U.S. distributor, Kluwer, Norwell, MA). 198 pp.,illus. $54.Through the Straits of Armageddon. Arms Con-

trol Issues and Prospects. Paul F. Diehl and Loch K.Johnson, Eds. University of Georgia Press, Athens, GA,1987. xxiv, 279 pp. $32.50; paper, $12.95.The Urban Naturalist. Steven D. Garber. Wiley,

New York, 1987. xiv, 242 pp., illus. $12.95.Water Resources Policy for Asia. Mohammed Ali,

George E. Radosevich, and Akbar Ali Khan, Eds. Bal-kema, Accord, MA, 1987. xii, 627 pp., illus. $63.75.From a symposium, Dhaka, Bangladesh Aug. 1985.Women of Science, Technorogy, and Medicine. A

Bibliography. Else Hyrup. Roskilde University Library,Roskilde, Denmark, 1987. viii, 132 pp. Paper. Skriftseriefra Roskilde Universitetsbibliotek, 15.Wrong Relativity and a New Mathematics. Two

Upsets of Established Belief Systems. Dallas Irvine.Green, St. Louis, MO, 1987. Variously paged, illus.Paper, $50.

12 FEBRUARY 1988

POSITIONS WANTED

Immunochemistry/tumor immunology, Ph.D., 4years of postdoctoral experience in glycoconjugate purifi-cation, characterization, and modification. HPLC,monoclonal antibodies, immunoassays, radioimmunno-scintigraphy in animal models and clinical trials. Supervi-sory and teaching experience. Seeks faculty-level academ-ic or industrial position. Box 19, SCIENCE.

Immunologist, Ph.D. Extensive background in academ-ic and biotechnology research and development. Experi-ence in hybridoma technology, large-scale cell culture,and lymphokines. In-depth knowledge of all phases ofproject and laboratory management. Seeking academic/industrial position. Box 20, SCIENCE.

Ph.D. Biology: Medical researcher in neurosciences.Four years of postdoctoral experience in neuroanatomi-cal techniques, anterograde and retrograde tracing, im-munohistochemistry, double labeling, histology, histo-chemistry, ELISA, tissue culture, etc. Seeking researchposition in industry or university. Box 24, SCIENCE.

POSITIONS WANTED

Microbiologist, M.S. seeking employment as researchassistant or lab technician. Have over 2 years of labora-tory experience in protein purification, column chroma-tography, bacterial cell culture, spectrophotometry, elec-trophoresis. Trained in microbial genetics and physiolo-gy, medical mycology, bacteriology, biochemistry, im-munochemistry, radioisotopes, electron microscopy.David Lambert, 1009 S.W. 17th Street, Willmar, MN56201; 612-235-7518.

Microbiologist, Ph.D. Research experience in genetics,microcosms, plasmid isolation and manipulations (in-cluding DNA probes), bacterial conjugation and trans-formation of anaerobic bacteria. Interests in genetics,plasmid molecular biology, food technology, engineer-ing, SEM, and Japan/Japanese. Seeking industrial orfaculty level academic position. Box 18, SCIENCE.

Ph.D. Biochemist. Two years of postdoctoral experi-ence in protein chemistry and enzymology. Strong publi-cation record. Seeks postdoctoral position in Canada.Box 23, SCIENCE.

Ph.D. Rctrovirologist. AIDS researcher with publica-tions and teaching experience. Cell biologist with somemolecular biology experience. Currcnt research focusedon the neurotropic determinants of HIV. Laboratorymanager with an overview of the functional biology ofthe HIV, and antiviral agents. Seeks academic/industrialor research position with the government in Washing-ton, DC area. Box 25, SCIENCE.

Science Writer/Editor: Zoology/physiology Ph.D., bio-chemical research publications, anatomy textbooks, au-thor of free-lance magazine and newsaper articles. Seek-ing writing/editing, ghostwnting, co a rative, consult-ing projects, any biomedical field. Write: Master Word-works, Route 2, Box 332, Fulton, MO 65251.Telephone: 314-642-9749.

Scientific Programming. Advanced scientific degreeand extensive experience in design and development ofscientific applications. IBM, Apple and VAX experience.Seeks long- or short-tcrm projects. Box 26, SCENCE.

POSITIONS OPEN

ACADEMIC POSITIONIN

MEMBRANE BIOLOGYDepartment of Physiology secks applications for a

tenure-track faculty position, in assistant professor work-ing in membrane biology. The Department tries tomaintain a good environment for serious research.

Please send a statement of your research plans anddreams, curriculum vitae, and the names of a few scientistsfamiliar with you and your work, to: R. S. Eisenberg,Chairman, Department of Physiology, Rush MedicalColiege, 1750 West Harrison, Chicago, IL 60612.

Eastern New Mexico University invites applicationsfor ASSISTANT PROFESSOR tenure-track position.Responsibilities: Teaching in general botany, vascularplant systematics, plant anatomy, plant physiology andintroductory courses in general biology; active research;university service. Qualifications: Ph.D. in field appro-priate to above description of duties. Effective date: 23August 1988 pending funding. Send letter of applicationdescribing teaching and research interest, curriculumvitae, official transcripts and three letters ofrecommenda-tion to: Dr. Newel Jorge , Chair, Search Commit-tee, Department of Life Sciencs, #33, Eastern NewMexico University, Portales, NM 88130 by 20 March1988. ENMU is an Affi AcionEqual OpportunityEmployer.

ASSISTANT PROFESSOR: A position in exercisephysiology for a Ph.D. with postdoctoral research experi-ence in muscle and its response to exercise. Individualswill be expected to obtain external finding, attractgraduate students and to teach. Starting date: 16 August1988. Submit letter of application, curriculum vitae,three reprints, and three letters of recommendation to:Chairman of the Search Committee: R. M. Enoka,Ph.D., Departennt of Exercise and Sport Sciences,University of Arizona, Tucson, AZ 8g721. Applica-tion deadline 11 March 1988. An Afiav AcionEqual Opportunity Employer.

PERSONNEL PLACEMENT 8II

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

LINE CLASSIFIED ADVERTISING DEADLINES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date).

POSTONS WANTED: 400 per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSITIONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth).$38.00 per line; $380 minimum, per week (minimumcharqe covers one inch on a single column; one inchequaTs 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad cost:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra line spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles located within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POUCY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday, ONE week prior to issue date. Cancellationsmust be in writing.

Send copy for all PositIons Wanted ads and LIneClassified ads less than 1/6 page in size (39 lines) to:

SCIENCE Classified Advertising1333 H Street, NW, Room 940

Washington, DC 20005Telephone: 202-326-6555

Send copy for Fractional Display ads, 1/6 page andlarger, and all Marketplace ads to:

Scherago Aociates, Inc.1515 Broadway

New York, NY 10036Telephone: 212-730-1050

Blind ad replies should be addressed as follows:Box (give number)

SCIENCE1333 H Street, NW

Washington, DC 20005

POSITIONS OPEN

ACADEMIC LABORATORY PATHOLO-GIST-The Department of Pathology at the Universityof Pittsburgh is seeking an academilc pathologist withinterest and experience m laboratory medicine for a fill-time faculty position at the assistant professor level. Thesuccessful candidate will work with three other patholo-gists in providing comprehensive laboratory services inan adult ambulatory care setting. Candidates must beBoard-certified or -eligible in CP though eligibility/certification in both AP/CP is also desirable. Applicantswith research intcrests in laboratory medicine are encour-aged to app. Responsibilities also include medicalstudent and resident education. Inquiries will be held instrict confidence. Submit curriculum vitae and biblioVa-phyto: University of Pittsburgh School ofMediane,Dqpartment of Pathology, 776 Scaife Hail, Pitts-burgh, PA 15261, Attention: A. Roman-Kolier. TheUniversity of Pittsburgh is an Affirmative Action/EqualOpportunity Employer. Deadline is 30 June 1988.ANATOMIST-UNIVERSITY OF CALIFOR-

NIA, SAN DIEGO VISrIING PROFESSOR posi-tion open to teach gross anatomy at the UCSD School ofMedicine, Department of Surgery, Anatomy Division.Qualifications indude: Ph.D. in anatomy or M.D. withequivalent training; Professor-level experience in teach-ing medical students gross anatomy with a strong clinicalorientation; Established expertise as a teacher in theuniversity setting; Experience and ability in administra-tion within an academic setting. Four-month appoint-ment (September through December 1988). Salary de-pendent on qualifications. Closing date: 1 April 1988.Successful candidate may be reappointed in future years.Send curriculum vitae and names of three academicreferences to: Nicholas A. Halasz, M.D.; Departmentof Surgery, 225 Dickinson Street, San Diego, CA92103.

ASSISTANT PROFESSOR OF BIOLOGY. Ap-plications are invited for the position of assistant profes-sor of biology, a tenure-track appointment beginningmid-August 1988. A Ph.D. in cellular/molecular biologyis required, and some teaching experience in biotechnol-ogy and/or plant science would be desirabk. Teachingduties will indude first-year biology courses and celibiology. The University of Houston-Downtown is anurban undergraduate institution with an enrollment of7,200. Send a letter of application, rcsume, and thenames and addresses of four references to: Dr. AlAvenoso, Department ofNatural Sciences, UniversityofHouston-bowntown, One Main Stret, Houston,TX 77002. Applications should be postmarked by 8March 1988. The University ofHouston-Downtown is anAffirmativeAction/Equal Opportunity Employer.

ASSISTANT PROFESSORMOLECULAR VIROLOGY

The Departments of Ophthalmology and Virology ofBaylor College of Medicine seek an innovative scientistto develop an independent researeh program on herpesvirus infections. Responsibilities also indude establishingand coordinating a diagnostic ocular virology laboratory.Applicants for this tenure-track position at the assistantprofessor level should have a Ph.D. with at least 2 yearsof productive postdoctoral experience in virology re-search. Salary is commensurate with cxperience. Negotia-ble starting date. Send curriculum vitae, names of at leastthrde references, and a statement of research interests to:Dr. K. R Wllhelmus, Chairperson-Search Commit-tee for Molecular Virologist Position, Department ofOphthalmology, C n vye Institute, Baylor Collegeof Medicne, One Baylor Plaza (NC200), Houston,TX 77030. Equal Opportunity Employer.ASSISTANT RESEARCH PHYSICIST. Applica-

tions are solicited for the position of assistant researchphysicist, to work in the area ofoptical studies ofsurfacesand thin films. Salary range will be $36,600 to $37,800for 12 months, depending on qualifications. A Ph.D.degree in a related field is required. Experience in thefollowing areas is important: Ultra high vacuum meth-ods; modem surface science electron spectroscopies,including AES, LEED, and XPS; laser Raman scatterngspectroscopy of solids and surfaces; prism techniques forradiation coupling to surface modes of thin films; Fouri-er transform mass spectrometry methods; pulscd lasertechnology. Applicants should send their r6sume to:Professor John C. Hmmiinaer, Department ofChemistry, University of hifornia, Irvine, CA92717. UCT is an Affirmative Action/Equal OpportunityEmplvyer.

8I2

POSITIONS OPEN

ASSISTANT DEANMEDICAL SCIENTIST TRAINING PROGRAMThe University ofTexas Southwestern Medical Center

at Dallas seeks an Assistant Dean to manage studentrecruitment for its expanded Medical Scientist TrainingProgram, a dual degree program that awards both M.D.and Ph.D. degrees to outstanding students who com-plete a rigorous course of study and research in medicineand biomedical science.The Medical Scientist Training Program is one of

twenty-five M.D./Ph.D. programs around the countrythat are funded by the National Institutes of Health. Alarge gift from Mr. Ross Perot has enabled Southwest-ern to double the enrollment of this highly selectiveprogram while ensuring that the very best students,wherever they may be, are attracted to it.The Assistant Dean will be expected to build a network

of professional contacts, particularly among premedicaladvisors, science advisors, and science department chairsat colleges and universities. This person will develop andmaintain an extensive database and file system dedicatedto student recruitment, will plan and undertake numer-ous recruiting trips, and will provide support and coordi-nation to the faculty as they assist in rcruitment andadmissions. The Assistant Dean will also assist the Direc-tor of the Program in administrative matters and willplan and coordinate activities for students enrolled in theProgram.The University seeks an energetic, enthusiastic, and

articulate individual who understands biomedical scienceand who conveys its excitement to students. A commit-ment to the highest standards and the ability to recognizeexcellence are essential. A doctoral degree is desirable.The person must be willing to travel extensively.The position carries an attractive salary and fringe

benefits commensurate with applicant qualifications.Resumes and letters of interest or nomination should

be sent no latcr than 1 March 1988, to:Dean's Office

Southwestern Medical SchoolThe University of Texas Southwestern

Medical Center at Dallas5323 Harry Hines Boulevard

Dallas, TX 75235-9003An Affir ive Acton/Equal Opportunity Eployer

ASSISTANT PROFESSORSHIPPOSMON IN SPINAL

RECONSTRUCTIVE SURGERYApplicants must have a specialty interest in bone

histomorphometry. Applicants must have completed anapproved spine fellowship and be capable of performingadvanced spinal reconstructive surgical procedures.Please send r6sume with salary history and requirementsto: Lee Riley, M.D., Department of Orthopedic Sur-gery, Harvey 611, Johns Hopkins Hospital, 600North Wolfe Strect, Baltimore, MD 21205. JobnsHopkins Universt is an Equal Opportunity EmplVer.

ASSISTANT/ASSOCIATE PROFESSORBIOCHEMISTRY/BIOPHYSICS

WASHINGTON STATE UNIVERSITYThe Biochemistry/Biophysics Program is seeking to fill

a tenure-track position beginning August 1988 or later.Appointment will be at the assistant or associate profes-sor level. Applicants should have research interests andexperience in strctural analysis of biological macromol-ecules or assemblies. Appropriate areas include applica-tion of x-ray crystallography, nudear magnetic reso-nance, electron microscopy or spectroscopy to elucida-tion of structure in proteins, nucleic acids, protein-nudeic acid complexes or more complicated assemblies,including membranes. Candidates should have a Ph.D. inbiophysics, biochemistry, or a related discipline, postdoc-toral training, and a record indicating outstanding abili-ties and potential in research and teaching. The successfulcandidate will be expected to develop and maintain avigorous research program supported by extramuralfunding, train graduate students, and particpate in grad-uate and undergraduate teaching. Send a letter of appli-cation, curriculum vitae, statement of research plans andthree letters of reference to: Dr. Gerald L. Hazelbauer,Faculty Search Committee, Biochemistry/BiophysicsProgram, Washington Statc University, Pullman,WA 99164-4660. Deadline is 15 March 1988 or untilposition is filled. WSU is an Equal OpporunitylAffirma-tiveActionEdutr andEmployfr. Protectedgroup membersare encouraged to apply and to identtfy their status.

POSITIONS OPEN

ASSISTANT RESEARCH SCIENTIST: Positionimmediately available for Ph.D. with 1 to 2 years ofexperience in molecular biology, and with a stronginterest in the neurosciences. Applicants using contem-porary approaches are particularly encou to apply.Please send curriculum vitae and statement of researchplans as well as names of three referees to: Joan Har-mon, Personnel Department, NYU Medical Center,550 First Avenue, Ncw York, NY 10016. An EqualOpportunity Employer M/F.

ASSISTANT SCIENTIST POSITION in the fieldof molecular and cellular biology reating to diabeticretinopathy research. Requirements include M.D. degreewith strong background m clinical diabetes plus at least 3years of research experience in molecular and cell biolo-gy. Publication record and ability to attract researchunding essential. Contact: Mara Lorenzi, M.D., EyeResearc Institute, 20 Staniford Street, Boston, MA02114.Equal Oppotunity/AjlrmativAion EmployerM/FIH/V.

ASSISTANT/ASSOCIATEPROFESSORS IN BIOLOGY

Two tenure-track positions available in an expandinDepartment of Biological Sciences. Modem well-equipped facilities and modem programs provide excep-tional opportunities for teaching and research. Nine- and10-month appointments start September 1988 at salariescommrensurate with qualifications and experience.BIOCHEMICAL ENGINEER: Teaching and re-

search position in a new biotechnology program. Teach-ing responsibifities indude courses in biotechnology,biochemical engineering and other departmental coursesrelated to area of expertise for undergraduate and gradu-ate (master's degree) students. Applicant must havePh.D.; demonstrated experience in fermentation anddownstream processing; and commitment to teaching ina prnmarily undergraduate program and directing studentresearch. Facilities include state-of-the-art fermentationfacility with downstream processing equipment.MEDICAL TECHNOLOGY: Ten-month position

with responsibilities of directing University's baccalaure-ate MT program; teaching clinical courses and courses inrelated area ofexpertise; maintaining rapport with associ-ated hospitals; and participating in departrental opera-tions. Applicant must have MT (ASCP) or equivalentcertification; recent clinical laboratory experience; anddoctorate in related fields. Those wishing to establishresearch programs are encouraged to apply.Mankato State University has a current enrollment of

15,000 students. The Greater Mankato area, population42,000, is located 80 miles from the Minneapolis-St.Paul Metro area. Scnd names ofthree references, curricu-lum vitae, complete undergraduate and graduate tran-scripts, and a brief statement of teaching and researchinterests to: Dr. John Frey, Chairperson, Departmentof Biolgy, Mankato State University, Mankato,MN56001. Applicant must be able to leg%y accept employ-ment in the U.S. and have demonstrated ability tocommunicate effectively with students and colleagues.Closing date for applications is 31 March 1988, or untilfiled.Mfankato State is an Equal OpportunityEducator andEmployer.

ASSISTANT/ASSOCIATE PROFESSOR OFPHYSIOLOGY. The DcpartmentofPhysiology, LoyolaUniversity of Chicago at the Medical Center is seekingcandidates for a tenure-track position at either the assist-ant or initial associate professor level. The departmenthas strong research programs in cardiovascular physiolo-gy and pathophysiology. We are seeking an individualwith a cellular and molecular emphasis which is comple-mentary to our systemic and integrative cardiovascularinterests. Candidates must have a Ph.D. or M.D., anindependent research program, and postdoctoral or pre-vious faculty status experience. A commitrnent to excel-lence in teaching medical and graduate students is re-quired. Applicants should send curriculum vitae includ-ing a list of publications, teaching experience, a briefstatement of research interests, and at least dthee namesof references by 15 March 1988 to: James P. Filkins,Ph.D., Professor and Chairman, Department ofPhysiology, Loyola University of Chicago, StritchSchool of Medicine, 2160 South First Avenue, May-wood, IL 60153.

Ioyola Umni y of Chico is an Equal OpportunitylAffirmativeAcion Emploer.

SCIENCE, VOL. 239

I IAFFINITY

CHROMATOGRAPHYCHEMIST

Sigma Chemical Company, a leadingmanufacturerofbiochemicals and organiccompounds, is seeking a Biochemist/Chemist for its afflnity chromatographygroup. Thesuccessfulcandidatewill havea degree in Chemistry or Biochemistryand experience in affinitychromatographypreparation techniques. Responsibilitiesinclude bench level production ofaffinitymedia, protein purification and new pro-duct development. The position requiresability to do independent work as wellas strong written and verbal communi-cation skills.

Sigma offer competidve salaryand fullcompany paid benefits. Please send resumewith salary history in confidence to:

Personnel Manager (CAM)SIGMACHEMICALCOMPANYP.O. Box 14508St. Louis, MO 63178An Equal Opportunity Employer

SIGCMA

| ~~PHYSICALBIOCHEMISTRY

GD. Searle is a worldwide leader in the pharmaceuticalindustry. Expansion within our Drug Delivery area has

created an outstanding opportunity for a Research Scientist whocan combine an understanding of the physical nature of proteinsand peptides derived from biotechnology with interdisciplinary teamsworking on drug delivery systems.Key responsibilities include:Develop, implement, and execute methods and procedures to charac-terize the physical and chemical properties of proteins, peptides,and small organics.Interact with interdisciplinary teams to develop delivery systems forparticularproteins, peptides, and small organics.Direct scientists and provide "hands on" support when necessaryto accomplish projects.Qualifications include a Ph.D. in Physical Biochemistry or relatedfield and 3-5 years of laboratory experience in the characterizationof physical and chemical properties of biological molecules. Welldeveloped oral and written skills required.This position offers an excellent salary, high visibility, and a compre-hensive benefits package. Our location offers access to a variety ofcultural and recreational facilities, several fine universities and activescientific community. Please submit your resume in strict confidenceto: G.D. Searle & Co., Professional Staffing, Dept. HG, 4901Searle Parkway, Skokie, IL 60077. An Equal Opportunity Employer.

SE4RLE_E

IN OUR PHARMACOLOGICAL R&D LABSTHE FOCUS IS ON INNOVATION

For creative scientists, BERLEX Laboratories provides the ideal setting to initiate in-novative projects. We are a growing pharmaceutical company and a leader in phar-maceutical R&D, and at our Cedar Knolls, NJ facility, you can work on one of the in-dustry's most talented teams of research professionals.SECTION HEAD OF BIOCHEMICAL PHARMACOLOGYDirect the work of several Ph.D. scientists and biologists in a multidisciplinary environ-ment to initiate novel research in cellular aspects of cardiovascular diseases. At thesame time, you will be encouraged to pursue your own scientific interests. Thebiochemistry section includes a new cell culture facility for basic research in vascularand cardiac pharmacology.To qualify, you should be a well-recognized professional in an area of biochemistry/phar-macology related to cell biology, and have demonstrated excellence in scientific creativi-ty. At least 5 years of postdoctoral experience is essential, as are good communica-tion skills and the ability to work in a team environment.

POSTDOCTORAL RESEARCH SCIENTISTWork with biologists and chemists on new approaches to the treatment of cardiovasculardiseases and initiate novel research in a multidisciplinary environment.To qualify for this two year appointment, you must be a Ph.D. in an area related tomuscle/endothelial cell biology.BERLEX provides a generous salary, comprehensive benefits, and unusual oppor-tunities for growth. Send your CV with salary history, in strict confidence, to: Attn: LILABERNSTEIN, Manager,Human Resources, R&D, Dept S, BERLEX LABORATORIES,INC, 110 E. Hanover Avenue, Cedar Knolls, New Jersey 07927. Equal OpportunityEmployer M/W/H.

IMMUNOCHEMIST-IMMUNOLOGIST

For Studies ofCytochromes P-450

Laboratory of MolecularCarcinogenesis

NATIONAL CANCER INSTITUTEPosition of Senior Staff Fellow or Ex-pert to use immunological andimmunochemical approaches, par-ticularly monoclonal antibodies tostudy cytochrome P-450 immuno-chemistry, their multiplicity, struc-ture and function, their role in themetabolism, activation and detox-ification of xenobiotic carcinogens,drugs and endogehous compounds.Salary Range: $20,688-$44,430. Ap-plicants must be U.S. Citizens, per-manent residents, or non-citizensfrom a treaty-allied country. Send cur-riculum vitae and three reference let-ters to Dr. Harry V. Gelboin, Chief,Laboratory of Molecular Car-cinogenesis, National Cancer In-stitute, National Institutes of Health,Bldg. 37, Rm. 3E24, Bethesda,Maryland 20892.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

("I

POSITIONS OPEN

ASSISTANT/ASSOCIATE PROFESSORNEURAL REGENERATION

The Departnent of Anatomy, School of VeterinaryMedicine, Purdue University, is seeking to fill twotenure-track positions at the kvel of assistant or associateprofessor (depending on experience). Their primary ap-pointment wil be in the Center for Paralysis Researchwhere their responsibility will be to develop and fundtheir own independent research laboratories within theCcnter. The candidates should posscss exemplary aca-demic credentials, and a corresponding record of grantacquisitions. Research ecperience should bc in mammali-an neuroscience, with an emphasis on development andregeneration of the nervous system. Relevant experiencecould indudc the analysis of behavioral deficits in spinalinjured mammals, spinal cord electrophysiology, tract-tracing techniques and analysis of electric field effects intissues. Novel approaches to problems of regenerationusing mammalian neuronal tissue culture techniques arealso of interest. Applications must bc accompanied by acurrent curriculum vitae, the names of three references,be postmarked no later than 15 March 1988, and beaddressed to: E. J. Hinsman, Departmcnt ofAnatomy,School of Veterinary Medicine, Purdue University,West Lafayette, IN 47907.Purdue Univ y is an Equal Opportunity/Affinnaie

Action Employer.

ASSISTANT/ASSOCIATE PROFESSOR OFPHARMACOLOGY-Applications are invited for atenure-track position available 1 June 1988. Responsibil-ities include teaching in a team-taught pharmacothera-peutics course and establishing a research program.Experience in neuropharmacologyof spmecial intercst.Undergraduate pharmnac degree also desirable. Interest-ed applicants should submit curriculum vitae and namesofthree references to: J. Mark Winston, PhD., Collegeof Pharmacy and Health Sciences, Drake Univmrsity,2842 Forest Avenue, Des Moines, IA 50311. AnEqual Oppomniy/AffwaiaiveAction Employfr.

U.S. DEPARTMENT OF ENERGYASSOCIATE DIRECTOR FOR HEALTHAND ENVIRONMENTAL RESEARCHOFFICE OF ENERGY RESARCH

The Dtment of Energy (DOE) is seeking appli-cants for Senior Executive Service position of asso-ciate director for Health and Environmental Rescarch.This executive plans, manages and assesses Office ofEnergy Rescarch supported basic and applied research.Program aspects include molecular and subcellular mech-anisms underlying human somatic and genetic processesand their responses to environmental toxicants; atmo-spheric, marine and terrestrial processes; nudear medi-cinc and epidemiology, structural biology, and advancedinstrumentation.Thep r candidate will be a U.S. citizen with a

M.D. or Ph.D. degree in an appropriate biologicalscience. He/she will have experience in directing basicand applied researh in health and medical sciences;integrating intemal and external program and policyissues; directing/guiding programs, projects, or policydevelopment; and program monitoring and evaluation.Salary range: $64,700 and $75,500. Position location:DOE facihity, Germantown, Maryland.Dirct inquiries to and obtain application materials

from: Ms. Rosalee Wdlliams-SM/8S/2,MA-204.1; Of-fice of Pernnl, U.S. DOE, 1000 In eAvenuc, S.W., Wasington, D.C. 20585, or call: 202-586-8461. Completed applications must be postmarkedno later than 2 March 1988.

U.S. DOE is an Equal Opportnity Employei.

ASSOCIATE RESE CH SCIENTISTS (twopositions) to study microvascular blood flow by intravitalmicroscopy in sickle cell disease and other blood disor-ders. Requirements: Ph.D. in bioengineering, physiolo-gy, or pathokogy. Related experience desirable. Sendcurnculum vitac with names of three references to: Dr.Herbert H. ipowsky, Department ofPhysiology andCellular Biopscs, College of Physicians and Sur-geons, Cohlumbia Univerity, 630 West 168 Strect,New York, NY 10032.

Columbia University is an Equal OpprtunityAffinnatieAction Employer

POSITIONS OPEN

BIOCHEMISTSBioActives Inc. is a rapidly growing company involved

in the development ofbiom andX ,chmcal prod-ucts based on novel molecules found in a variety ofnatural products, particularly invertebrate venoms. Weseek two biochemists to isolate and purify bioklgicallyactive molecules from venoms and to assist in determin-ing their structures. One position requires a Ph.D. inbiochemistry or chemistry, and extensive practical experi-ence in high-performance liquid mato hy(HPLC); the other position requLres a bachelor's degreeand HPLC experience. The positions are available inme-diately. The salary is negotiabk and depends uponexperience and qualifications. A generous benefits pack-age is offered. Please apply by sending curriculum vitaeand the names of three refrees s to:-Dr. T. N. Parks,BioAcdves Inc., 420 Chipet Way, Univsity ofUtah Rcsearch Park, P.O. Boa 8327, Salt Lake City,UT 84108. An Equal Opportunity Emloyer.BIOCHEMISTRY/MOLECULAR BIOLOGY

MEHARRY MEDICAL COLLEGETwo faculty positions are available in July 1988 in the

Department ofBiochemisty at the level of ASSIST-TOR ASSOCIATE PROFESSOR for well-

trained or experienced candidates in biochemistry andmolecular biology/molecular genetics. Successfult appli-cants will be expected to develop and/or maintain afunded research program of high quality and to partici-pate in the graduate and professional (medical, dentaland allied hcalth) school teaching programs of the Dc-partment. Applicants should send curriculum vitac,names of four individuals who may be contacted forreference, and a snunary of research intcrests or ongo-ing projects to: Ifeanyi J. Arinze, Ph.D., Chairman,Department of Biochenist, Meharry Medical Col-kge, Nashvill, TN 37208. Deadline fior rceipt ofapplications is 1 April 1988. Mehaty MedcalC isan Equal OpportuniyAffimativct Emo r.

BIOLOGICAL OCEANOGRAPHERDALHOUSIE UNIVERSlTY

The Department of Oceanography at Dalhousie Uni-versity in Halifax, Nova Scotia invites applications for atenure-track position in biological oceanography, efifc-tive 1 July 1988. Applicants should have a doctoraldegree in oceanography, and a strong, proven trackrecord in quantitative approaches to biological oceano-graphic problems. The successfil applicant would beexpectedtO interac vith physical, chemical, and grologi-cal oceanographers both at the research and taingleve. Weight will be given to those candidates whoseresearch programs integrate a quantitative, problem-solving approach to pelagic or benthic processes into abroad oceanographic context.

Interested individuals should send a copy of theircurriculum vitae, the names of at least three referes, anda briefsununary of past rescarch achievements and fituregoals to: Dr. A. J. Roen, o Ockanogra-phy, Dalhousie Unirsity, Halifax, Nova Scotia,3H 4J1.Deadline for applications is 31 March 1988. In acord-

ance with Canadian Immgration requirments, thit adver-tisement is dirctdpim to cins or pe n restdents of Canada. Daihousie Uips hs apoliq ofAffinniaAciaon with repect to the e y ofwomenfacsuty.

BIOLOGYHARTWICK COLLEGE

Applications are invited for two full-time positions.Commitmcnt to undergraduatc tcaching and the Ph.D.(or near completion) are required.

(i) DEVELOPMENTAL BIOLOGY-A tenurc-track position, to teach embryology, comparativc anato-my, gencral biology, and a new coursc in the arca ofdevelopmcnt for non-majors, and to direct undergradu-ate rcscarch in animal developmcnt. A strong molecularbiology background is preferrd.

(ii) ECOLOGIST-A 3-year appointment with thepossibility of renewal, to teach ecology (upper-levelcourse for majors), cvolution, forest ecology, and acourse in area of ecpertise, and to direct undegraduateresearch in ecology. A strong statistical background is

Send lettcr of application, rdsumE, and three leters ofreference by 26 Fcbruary 1988 to: ML Richard Sena,Chair, Deprtment of Bioogy, Harnwick ColOneonta, NY 13820. An Equt Opportunity Employer.

POSITIONS OPEN

BOTANISTNATURALIST, ASSISTANT PRO-FESSOR. Tenure-track position for an individual com-mitted to excllence in teaching and having an intcnt toconduct ficld-oriented research with the participation ofundergraduatc and/or graduate students. The positionincludes the teaching of botany, ecology and generalbiology courses and coordinating ofeducational comput-ing activities. Earned doctorate in a biological science,demonstrated ability in research and cassroom, andcomputer literacy are required. Send curriculum vitae,statement of research interest and names of three refer-ences to: Dr. J. Michael McCormick, Chair, Depart-ment ofBiology, Montclair State Collee, Box C316,V-12, Upper Montclir, NJ 07043. Closing datc forapplications is 1 March 1988. Montclair State Collge isan Equal Opportuit/finieArction Insiuto.

CHEMISTRY, DEPARTMENT CHAIRBALL STATE UNIVERSITY

MUNCIE, INDIANAThe Chemistry Department at Ball State University

invites applications and nominations for DepartmentChair. Candidates must have a Ph.D. in chemistry. Weintend to scelct candidates for interviews who can teachin the areas of inorganic chemistry or biochemistg.Experience in relating lectronic technology to the teach-ing of chemistry would also be welcome. In addition todemonstrated leadership and administrative abilities, thesuccessfil candidate wil bc required to develop an activeresearch program for undergraduatc and master's degreestudents. Our department of 13 faculty is dedicated toexcellent teaching and research. We will begin evaluatingapplications 11 March 1988 and continue until theposition is filled. Women and minoy candidates arencoureged to apply. Send r6sum6, official transcripts,researchplan, and three original leters of reference to:Dr. Ralph Jer, Chair, Dprm t of Chemistry,Bal State Univei, Munce, IN 47306.BaU State Uiverst Pntcer Equal Opportuity in

Education and Emplyment.COLLECTION MANAGERDIVISION OF FISHES

Field Musuem of Natural History, Division of Fishcsseeks to fill full-time staff position having primary re-sponsibility for the maintenance and carc of collection ofworld-widc scope. Dutics include identification, cura-tion, loan mana t as well as responding to scientificand pubic inquins. Will also bc cexpectd to coordinatewith cataloguin and skeletal preparation prorams, andto superisetucnt and volunteer assistants. Opportuni-ties for teaching and participation in field work andresearch. B.S. and 3 years of experience in majormuseumcollection or equivalent required. Previous supervisoryand computer experience desirabl. Send curriculumvitae with names and telephone numbers of three refer-ences, and statement of career objectives to: KathrynHill, Field Museum of Natural Histo RoosevltRoad at Lae Shore Drive, Chicago, ILd605. Appli-cation deadline is 26 February 1988. FiedMuseum s anEqual ppeutEmployer. Women and minots en-

DIRECTORINTERDISCIPLINARY CENTER FORBIOTECHNOLOGY RESEARCHTHE UNIVERSITY OF FLORIDA

The University of Florida is seeking applicants for theposition of Director of the Interdiscplinary Center forBiotechnolgy Rcscarch. The Center was founded inMay 1987 to foster research and develpment in themolecular life sciences, and is funded by a special legisla-tive initiative. The Director will codinat all biotech-nology activities at the University of Florida.We invite nominations of, or applications from, indi-

viduals with an camed doctorate and a strong record ofachievement in scholarship and research.

Applicants should provide curriculum vitae, a briefdescription of current activities, and three letters ofreference to:

Roxanna AM BruceOffice of the Vice President for Reearch

223 Grinter HallUniversity of FloridaGaieviie FL 32611

The dosing date for applications is Friday, 1 April1988.The Unierity ofFlorida is anAffinnativeAtioiEqual

Opportunity Employer.

SCIENCE, VOL. 2398I4.

* Land and Water Quality StudiesEPRI, on the San Francisco Peninsula, an R&D firm chartered to pro-vide research and development for all segments of the U.S. electric util-ity industry, seeks a senior professional to develop technical requirementsand to initiate and manage research contracts in land and water qualitystudies. Specifically, you will develop research concepts, prepare proj-ect implementation strategies, and manage research on the environmentalbehavior and fate of chemicals (especially organics) discharged by util-ity operations.

Candidates will have a PhD/Earth Sciences (or equivalent related field),5-10 years experience in conducting and directing research in ground-water quality and soils contamination, experience in conducting geo-

chemical and hydrochemical experiments and modeling. Provenmanagement ability in contract research and good communication skillsrequired. Knowledge of electric utility industry wastes desirable.EPRI offers a stimulating environment, competitive salaries and compre-hensive benefits. For immediate consideration, please send your resume,including salary requirements, to D. Staten, Human Resources Dept.SCI-763, EPRI, 3412 HilMew Avenue, P.Q Box 10412, Palo Afto, CA 94303An equal opportunity employer.

EPRELECTRIC POWER

RESEARCH INSTITUTE

DEPARTMENT OF HEALTH AND HUMAN SERVICESPUBLIC HEALTH SERVICE

NATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESOPENING DATE: January 18, 1988 CLOSING DATE: March 4,1988

(All applications must be postmarked before closing date)Position: Director, Division of Digestive Diseases and Nutrition

The National Institute of Diabetes and Digestive and KidneyDiseases invites nominations and applications for the position ofDirector, Division of Digestive Diseases and Nutrition (DDN). Thecandidate must be internationally recognized within the scientificcommunity as an authority in digestive diseases. In addition, thecandidate should demonstrate an interest and a commitment tonutrition research. This Institute conducts, fosters, and supportsresearch and research training in the prevention, management,and cure of diabetes and related endocrine and metabolicdiseases; kidney, urologic and hematologic diseases, anddigestive diseases and nutrition. Programs encompass intramurallaboratory research and extramural (grants and contracts) ac-tivities in fundamental diabetes digestive and kidney disorders.The incumbent serves as the primary official with responsibilityfor planning and executing the Institute's digestive diseases andnutrition extramural programs. This includes basic and appliedresearch, training fellowships, institutional training awards,multipurpose research centers, clinical trials, and data collection.Advises and participates with the outside voluntary healthorganizations and the National Advisory Council in identifying andaccessing the needs and requirements for research and manpowerdevelopment in the digestive diseases and nutrition disorders. Ad-ditionally, the incumbent serves as principal advisor to the In-stitute Director on matters and policies pertaining to these areas.Also, the incumbent will conduct intramural research projects inthe areas of digestive related diseases and nutrition.This is a Civil Service position in the Senior Executive Service(SES), with a salary range from $64,760 to $73,400 per annum,depending on qualifications. Currently the payable salary islimited to $73,400. Physicians may be eligible for an additionalcomparability allowance up to $10,000 per year. (Alternatively, can-didates may be eligible for appointment in the Commissioned

Corps of the U.S. Public Health Service). Mandatory profes-sional/technical qualifications are a medical degree and researchprogram administration and/or clinical experience in digestivediseases and nutrition. Further information on these qualificationsare available by contacting Mr. Syd Carter, Personnel Manage-ment Specialist, National Institute of Diabetes and Digestive andKidney Diseases, 9000 Rockville Pike, Building 31, Room 9A30,Bethesda, Maryland 20892, (301) 496-4231.Mandatory managerial/executive qualifications include evidence ofmanagement of a basic or clinical research program,demonstrating ability to assume leadership responsibilities indeveloping program goals; representing the program to outsidegroups; directing program planning, execution, and evaluation;and conducting a fair and equitable employment program, in-cluding the attainment of EEO objectives.Candidates who meet the mandatory qualifications will be furtherevaluated by the Search Committee on the degree to which theyexceed the mandatory managerial/executive qualifications, and onthe following desirable qualifications: scientific reputation/peerrecognition, training and education, leadership of a basic orclinical research or research administration program, and honorsand awards.APPLICATIONS (APPLICATION FOR FEDERAL EMPLOYMENTSF-171) should be sent to Mr. Clifford Moss, Executive Secretary,Search Committee for Director, DDN, Building 31, Room 9A30, Na-tional Institute of Diabetes and Digestive and Kidney Diseases,Bethesda, Maryland 20892, telephone (301) 496-4231.

A current curriculum vitae and bibliography must accompany allapplications. Applications from women and/or minority groupmembers are especially solicited.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

DEAN, DENTAL SCHOOLTHE UNIVERSITY OF TEXASHEALTH SCIENCE CENTERSAN ANTONIO, TEXAS

Nominations and applications are invited for the position ofDean of the Dental School of The University of Texas HealthScience Center at San Antonio. In addiion to its interest ininnovative teaching, the Dental School has a special commit-ment to scholarship and research, an expanding program ofcommunity service, and comprehensive patient care. Teach-ing, research and community programs are enhanced by closeintegration with programs and faculty of the other schools ofthe Health Science Center-the Graduate School of Biomedi-cal Sciences, the School of Medicine, the School of AlliedHealth and the School of Nursing. The Dental School enrolls368 students in the undergraduate program and 91 studentsin the graduate residencies and Masters programs, whichinclude Dental Diagnostic Science, Endodontics, Periodontics,Pediatric Dentistry, Prosthodontics, Oral Surgery, the GeneralPractice Residency Program and the Advanced Education inGeneral Dentistry Program.Candidates must have prior experience in academic adminis-tration, planning, and fiscal matters, as well as an estab-lished record of scholarship and research. The Dean reports tothe President of the Health Science Center, provides leader-ship for the dental school's 207 full and part-time faculty,participates in govemance of the University through member-ship on the Health Science Center's Executive Committee, andworks closely with the dental practicing community.All nominations and applications should be received by March31, 1988. Further information is available from and nomina-tions and applications, including a curriculum vita, should besubmitted to:

Joseph M. Berrong. D.D.S.Chairman, Dentl Dean Search CommitteThe Uniersiy of Texas H.S.C.Department of General Practice7703 FlW Curl DrieSan Antonio, Toxas 78247914(512) 567-3450

The University of Texas Health Science Center at San Antoniois an Equal Opportunity/Affirmative Action Employer.

...j

0

F0 m

7

Hybrldoma/Monoclonal

_ ybrldoma/Monoclonal=Antibodies

Abbott Laboratories. A S4.4 billion leader in health careproducts recognized for exceptional management and ahighly advanced scientific environment. A history ofbreakthrough R&D has made our Diagnostics Divisionthe undisputed world leader in Diagnostics. Now,we seek a Scientist to participate in our aggressiveresearch studies.This position will inlve the development of monoclonalantibodies for new immunoassay products, and willrequire some supervision of technical personnel. Thequalified candidate will be a PhD Immunologist or CellBiologist with at least 2-3 years experience in theproduction and characterization of mornoconal antibodies.Abbott is located in an attractive suburban setting just30 miles north of Chicago on the Lake Michiganshoreline. We offer an excellent salary and fullbenefits package that includes profit sharing and stockretirement plan. For consideration, send your resumeincluding salary history in confidence to: Peggy Taylor,Corporate Placement, Dept. SCV2-12. Abbott is anaffirmative action employer.

ABBOTT PARK IL 60064"HEALTH CARE WORLDWIDE"

i-

XOMA Corporation, a leading biotechnology oompany lo-cated in the San Francisco Bay Area is currently in search ofa PhD to assume the scientific & administrative direction ofthe Toxicology & Animal Research Department. This hands-on manager will be responsible for acute and subcronic toxi-cology studies under GLP guidlines, pharmacokenetic andtissue distribution studies and efficacy studies using modelsystems appropriate for product development programs.

The ideal candidate will possess a PhD in Pharmacology,Toxicology or related discipline. 3-5 years post doctoralexperience and experience with tumor model systems andGLP toxicology studies.

To explore this opportunity further please send your CVand salary history to:

Director of Human ResourcesXOMA Coporation

2910 7th St.

EOE Berkeley, CA 94710

ICRISAT'V needs a

PRODUCTION AGRONOMISTat Hyderabad, India

The International Crops Research Institute for the Semi-AridTropics (ICRISAT) seeks applications for the post of ProductionAgronomist. He/She will work with a team including agronomists,agroclimatologists, soil scientists and economists and will beresponsible for planning and implementing a program of fieldresearch at ICRISAT Center and on farms beyond the Center inassociation with the national research service. Contact with similarprograms in the international institutions will also be required. Theprogram of the Production Agronomist will center on the develop-ment and testing of management systems which increase andstabilize the yield of grain and fodder from crops grown in thesemi-arid tropics. Emphasis will be placed on the need for efficientresource use and for the long-term sustainability of productionsystems.Essential Qualifications: A Ph.D. in agronomy or clearly relatedaspectof agricultural sciencewith at least5to lOyears'experiencein the management of crops and/or fodder species in a researchinstitute or university. A good knowledge of English is essentialand preference will be given to candidates with experience oftropical agriculture and of trials on farms.The position is for 2 years with possibility of extension. Salary at

principal staff level, according to qualifications and experience.Send resum6, including present salary level and names ofthree refer-

ences within 60 days from the date of the advertisement, to:The Director General, ICRISAT, Patancheru, A.P. 502 324, India.

Postdoc inProtein Biochemistry

Genentech, Inc., a leader in the field of biotechnology, iscurrently seeking a Postdoc in Protein Biochemistrv to char-acterize growth hormone binding and signal transductionby the growth hormone receptor. To qualify, you should beable to apply a variety of methods to the purified, solubilizedreceptor including spectroscopic analysis, chemical modi-fication, monoclonal antibody mapping, limited proteolysisand conformantional analysis. A background in chemistryand experience with receptors or membrane proteins wouldbe a plus.Genentech, Inc. offers an excellent salary and benefits pack-age, coupled with the opportunity to make a significant con-tribution to our organization. Please send resume to: SherrieD.L. Wilkins, Genentech, Inc., 460 Point San Bruno Blvd.,South San Francisco, CA 94080. An equal opportunityemployer.

Genentech, Inc.3(Bn(S[n(&Goh Dn(&

OUR LABORATORIES0)11 IALSO DEVELOP

[SUCCESSFUL CAREERSPHARMACEUTIcAL

G@x SCIENTISTSGlaxo Inc. is one of thepremier research basedpharmaceuticalcompanies in America. Ranked in the nation's Top 10, we are atechnically advancedforcefor innovation that is constantlyadding new and important ethical andproprietarypharmaceuticals to its long list ofsuccesses.We are offering important, career expanding positions in ourPharmaceutics Department to Scientists who would like to beinvolved with the newest technology, the most challengingprojects, and major new product introductions.

Join us in one of these cballenging positions in ResearcbTriangle Park, N.C. (near Raleigb/Durbam)

RESEARCH ASSISTANTS, ASSOCIATES,AND RESEARCH SCIENTISTSProduct Formulation /Clinical Supplies Manufacturing

Candidates will be involved with allphases ofGlaxo's diversifiedR&D dosageform developmentprograms. Familiarity withCGMP's, clinical supplies manufacture andproduct scale- up isrequired. Manufacturing experience is desirable. Thesepositions offer excellent opportunities for world- wide travel.

Candidates responding to this posi1ion sbould refer toJob Pb. D. on all resumes.

CLINICAL SUPPLIES PROJECT LEADERClinical Packaging and SuppliesWorking in our Pharmaceutical Development Department, youwill be responsible for coordinating Pharmaceutics, AnalyticalChemistry, Medical, Biostatistics and Regulatory Affairsclinical development supplies activities; coordinating clinicalsupplies inventories obtainedfrom contract suppliers and ourUnited Kingdom parent; and, assisting in the clinicalpackaging and labeling study design. This is an excellentopportunityfor travel to contract manufacturers, packagersand to Glaxo UKQualified candidate must have a BS in Pharmacy or relatedfield with 2 -5years relevantpharmaceutical industry experience.Must have excellent oral and written communication skills andorganizational skills.Candidates responding to this position sbould refer toJob Pb. D. - I on all resumes.At Glaxo, growtb opportunities are complemented by a locationthat has excellent resources in close proximity. Prestigiousuniversities, scenic vistas, lively recreational areas, andexciting cultural opportunities ... all a part of the daily life ofthe Glaxo professional.Further, we reward talent and creativity with excellent salaries,comprebensive benefits programs (including a completelyequipped, on -site athletic facility) and rapid recognition.Candidates interested in these positions, please send yourresume, including salary history and CORRESPONDINGJOBEAS MENTIONED ABOVE, to:

Human Resources Department

Glax(o Inc IPO Box 13398

Research Triangle Park, N.C. 27709

(No Pbone Cal, Please)No Private Aency Referral, Please

An Equal Opportunity Employer M/F/HI/V

Paving the way to a healthier world.

DIRECTOR OFCLINICAL RESEARCH

Nelson Research & Development Company head-quartered on the University of California campus inIrvine - adjacent to the medical school - is asmall, highly creative research company com-mitted to the discovery and development ofnew drugs.Our recent acquisition by the Ethyl Corporationaffords us the opportunity to expand our ProductDevelopment activities. As part of this expansion,we have the need for a dynamic individual to headour Clinical Research DepartmentReporting to the Vice President of Developmentyou will be responsible for initiating, planning andcoordinating all clinical trials to support productregistration of our novel therapeutic agentsworldwide.

The ideal candidate will hold a Ph.D., or M.D. andwill have a minimum of 5 years industrial experi-ence or ademonstrated ademic research achieve-ment in a clinical facility. Excellent oral and writtencommunication skills are obviously essential.The position offers a rare challenge and uniqueopportunity for professional growth along with thechance to contribute to the overall success of agrowing Company.Nelson Research offers a professional environ-ment and competitive salary and benefits. Inter-ested candidates may send their resume withsalary history to:

Personnel ManagerNelson Research & Development Company

1001 Health Sciences Rd. WestIrvine, CA 92715

An Equal Opportunity Employer

SENIORASSISTANTSCIENTIST

PHARMACOLOGYParke-Davis Pharmaceutical ResearchDivision, Warner-Lambert Company hasan immediate opening for a researchscientist for our cardiovascular drug dis-covery/development program. This indi-vidual will assist in developing testingprocedures, conduct experiments, ana-lyze experimental data, and prepare re-search reports. The successful candidatewill have a strong background in cardio-vascular research and will possess therequisite technical skills.QUALIFICATIONS: MS in physiology orpharmacology with emphasis in cardio-vascular research, or BS with 2-3 years ofexperience in cardiovascular pharmacol-ogy. Experience working with laboratoryanimals and good communication skillsare essential.

Qualified applicants should send re-sume/curriculum vitae in confidence to:Ms. Sharon Moorehead, Parke-Davis,2800 Plymouth Rd., Ann Arbor, Michi-gan 48105.

"EQUAL OPPORTUNITY IN ACTION"

PARKE-DAVISDIVISION OF *^ANER LAM8E'T COMPAN-

POSITIONS OPEN

CHAIR, DEPARTMENT OFBIOCHEMICAL PHARMACOLOGY

The School of Phannacy of the State University ofNew York at Buffalo invites nominations and applica-tions for the position ofChair, Department ofBiochemi-cal Pharmacology. The appointee should hold a Ph.D. orM.D. degree and have an established, funded and cre-ative research program in an area of molecular pharmna-cology. The School of Pharmacy offers an already stimu-lating research environment in its graduate departmentsof Biochemical Pharmacology, Medicinal Chemistry andPharmaceutics and plans to strengthen, in collaborationwith the Department of Biology, its research capabilitiesin appropriate areas of molecular biology. The appoint-ment will be made at the level of associate or fullprofessor and opportunities exist for additional facultyappointments. Applications and nominations should besubmitted by 15 April 1988: David J. Trigple, Ph.D.,Dean, School of Pharmacy, State University ofNewYork at Buffalo, 126 Cooke Hall, Buffalo, NY 14260.

The State Univsty ofNew York at Buffalo is an EqualOpportunity/AffirmatipeAtion Employer

UNIVERSITY OF OTAGODUNEDIN-NEW ZEALAND

CHAIR OF PHYSICSApplications are invited for appointment to a Chair in

the Department of Physics. Applicants should have asubstantial research record in some area or areas ofphysics, preferably in a field with some broad connectionto those fields currently pursued in the department-atomic and laser physics, the physics of the magneto-sphere and the earth's environment, thin-film optics,energy physics, medical physics.

Professorial salaries are presently paid within the range$NZ68,000 to $NZ85,000 per annum.

Furthcr particulars are avaiable from the undersigned,P.O. Box 56, Dunedin, New Zealand.

Applications quoting reference number A87/85 closewith the Registrar on 31 March 1988. or as soon aspossible thereafter. D. W. Girvan, Registrar.

CYTOSKELETON POSTDOCTORALPOSMON

Postdoctoral position is available to study cytoskeletalreorganization in lving cells. Questions to be examinedindude cell motility, cell division, membrane-cytoskekl-ton interactions, oncogenic transformation, and myogen-esis. The approach involves state-of-the-art methods offluorescence niicroscopy, microinjection, image intensifi-cation, digital imnage processing and fluorescence pho-tobleaching.

Applicants should submit curriculum vitae, descrip-tions of previous research with reprints, and three lettersof recommendation to: Dr. Yu-li Wang, cto PersonnelOffice, Ceil Biology Group, Worcester Foundationfor Experimental Biology, 222 Maple Avenue,Shrewsbury, MA 01545.An Equa OpprtunityMAffinaiveAction EmployerM/FIH.

DEAN, COLLEGE OF LIFE SCIENCESAND AGRICULTURE

UNIVERSITY OF NEW HAMPSHIRE (UNH)UNH seeks an energetic/innovative leader for its newly

restructured College of Life Sciences and Agriculturewhich now indudes all eight biological science depart-ments. as well as departments with emphases in agricul-ture and natural resources. UNH is both a Land Grant/Sea Grant institution, with a total enrollment of approxi-mately 10,500. In addition to 10 departennts with 25major curricula leading to B.S. or B.A. degrees, 13 M.S.programs, and 7 Ph.D. programs, the Dean has responsi-bity for the New Hampshire Agnculture ExperimentStation and the Thompson School of Applied Science,which offers six 2-year programs leading to an A.A.degrec. Applicants should possess an earned doctorate, arecord of successful teaching/scholarly achievement anddemonstrated taknt for administration. A letter of inter-est, curriculum vitae, and the names offive references arerequested. Non-citizens must include current visa status.Salary will be competitive and commensurate with expe-rience. Nominations and applications should be sent to:Joan Weeks, Secretary, Office of VP for AcademicAffairs, Thompson Hail, University of New Hamp-shire, Durham, NH 03824. Application screening be-gins 29 January 1988 and applications will be accepteduntil the position is filled. UNH is anAffirmativeAcionlEqual Opportunity Employer.

8I8

POSITIONS OPEN

COUNTY DIRECTOR/ADVISOR: The Universi-ty of California, Division of Agriculture and NaturalResources, Cooperative Extension (CE) is seeking acareer-track academic candidate who is responsible forthe conduct of CE Program in Colusa Co. Administer,direct and provide leadership. Develop and implement aneducational program. A minimum of master's degree orequivalent combination of education and experience inone of the following areas: Home economics, humandevelopment, consumer science, or in other disciplinesapplicable to CE in Colusa County is required. Five yearsof experience at the county level preferred. Assure Affir-mative Action in development and delivery of programs.Salary in the assistant dtrough associate advisor rank. Forcomplete description, contact: CE Personnel, 6thFloor, 2120 University Avenue, Berkeley, CA 94720.Tclephone: 415-6444320. Closes 4 March 1988. Re-fer #A-87-180. AffirmativeAtionlEqual OpportunayEm-ployerM/F/H.

DEAN, COLLEGE OFLIBERAL ARTS AND SCIENCES

The University of Colorado at Denver seeks a personto provide vigorous academic leadership and directionfor the faculty ofthe College ofLiberal Arts and Sciencesin an institution committed to excellence in research/creative work and teaching. Appointment is planned forno later than the fall of 1988.

Please send nominations and applications, which in-dude a letter and an up-to-date curriculum vitae by 4March 1988 to: Dr. Bmce W. BergLand, Chair, CLASDean Search Committee, University of Colorado atDenver, 1200 Larimer Street, Campus Box 168-C,Denver, CO 80204-5300.

The Uniesity ofColorado at Denver is anEqual OpportunitylAffirmativeActon Employer

DIRECTOR, DIVISION OFINFECTIOUS DIS-EASES: The Department of Internal Medicine of St.Louis University School ofMedicine invites applicationsand nominations for the position of Director of itsDivision of Infectious Diseases. We seek a physician-scientist with a substantial publication record and ahistory ofpeer-reviewed grant support. The Director willbe responsible for developing and leading a vigorousresearch-oriented Division. Generous new research spaceand financial support will be provided. Please forwardnominations and applications to: Coy D. Fitch, M.D.,Chairman, Department of Internal Medicne, St.Louis University School of Medicine, 1325 SouthGrand Boulevard, St. Louis,MO 63104. Equal Oppor-tunity Employer M/FIVIH.

ENVIRONMENTAL STUDIES: The Environ-mental Studies Program at Williams College seeks a 1-year sabbatical leave replacement for 1988 to 1989 withthe possibility that a regular opening will occur in thefollowing year. Teaching responsibdlities will includecourses in the candidate's fiefd, incuding one with apolicy focus and probably an introductory course. Thecandidate is expected to have a Ph.D. degree or equiva-lent, and expenence in the environmental field. Rank andfield are open, but prefcrence will be given to candidateswith a bacgound in public policy, environmental law orengineering, geography or human ecology.

Excellent facilities for scholrly research are available.Send curriculum vitae and the names of three referencesto: Professor William R. Moomaw, Director, Centcrfor Environmental Studies, W'iliams College, Wil-liamstown, MA 01267. Applications should bc receivedby 29 February 1988. Wiliams ispartiulary interested inattracting women and minory caniates.

The School for Field Studies (SFS) seeks innovativeFACULTY (Ph.D./M.S., field leadership, and relevantresearch experience) for undergraduate 1-month summercourses on Acid Rain (Northeast United States), CoralReef Ecology (Virgin Islands), Alpine Ibex BehavioralEcology (Switzerland), Deforestation (Costa Rica),Humpback Whale Ecology (Gulf of Maine), Ecology ofSeabirds (Scodand), Coastal Ecology (Sardinia) andLandscape Ecology (Colorado). Salary: Senior faculty$2100 to $2400; associate faiulty $1300 to $1600 percourse plus travel/field expenses. Send letter, curriculumvitae, and three references to: Prgram Director, SFS,376 Hale Street, Beverly, MA 01915. Equal Opportu-nity Employer.

POSITIONS OPEN

EUKARYOTIC CELL BIOLOGISTIndiana University of Pennsylvania and the Biology

Department invites applications for a tenure-track posi-tion at the assistant/associate professor level in eukaryoticcell biology starting fall 1988.

Qualifications: Ph.D., and should have teaching cxpe-rience and a strong research record. Commitment toquality teaching and research is essential. Preference willbe given to applicants with a specialty in the molecularbiology of yeast.

Duties: Will indude teaching undergraduate cellphysiology, M.S. level graduate courses, establishing aquality research program, and teaching department gen-eral course offerings.

Submit letter of application, r6sumr, undergraduate/graduate transcripts, statement of research goals, andthree letters of reference to: Dr. William E. Dietrich,Jr., Cellular Biology Search Committee, Biology De-partment, Indiana Univeity of Pennsylvania, Indi-ana, PA 15705. Application deadline has been extendedto 1 March 1988. Minonty applica arc encuruWed toapply.

IUP is an AffirmativeAction/Equal Opportuity.

EXPERIMENTAL ZOOLOGISTApplications are requested for a junior-level faculty

position (tenure-track assistant professor, dependingupon experience) in a research division devoted to thestudy of cephalopods (presently four faculty, total 18personnel). Within the division is a large mariculturefacility in which numerous cephalopod species are cul-tured throuhout the year. Faculty and staff expertise liemainly in e areas of animal behavior, neuroscience,nutritional biochemistry, and pathology. Considerabkpotential exists for porductive, interdisciplinary collabo-ration. Applicants should have a background in zoology,postdoctoral training, and specific experience in aquaticanimal physiology. Preference will be given to candidateswith interests in postembryonic developmental studiesrelated to physiology. The successful applicant will beexpected to maintain a vigorous research program andconduct a minor amount of teaching at the graduatelevel. Please send curriculum vitae, names, and addressesof three references and a description of future researchgoals to: Roger T. Hanlon, Ph.D., Chief, Division ofBiology and Marine Resources, Marine BiomedicalInstitute, University of Texas Medical Branch, 200University Boulevard, Galveston, TX 77550-2772.UTMB is an Equal Opportunity Employer.

FACULTY POSMIIONS INAPPLIED BIOCHEMISTRY/MOLECULAR BIOLOGY

OREGON GRADUATE CENTERThe Oregon Graduate Center is expanding its program

in bioconversion technology. We are inviting applica-tions for the following positions:FUNGAIfYEAST MOLECULAR BIOLOGIST:

Experience in gene expression/regulation, protein secre-tion, or biodegradation with novel organisms.MICROBIAL BIOCHEMIST: Background in bio-

chemistry and/or molecular biology with experience inthe degradation/transformation of natural or xenobioticcompounds.PROTEIN BIOCHEMIST/ENGINEER: Back-

ground in protein chemistry, enzymology, immunologyand/or genetic engineering. Prefer candidates with expe-rience in utilizing molecular genetics to study structure-function relationships with enzymes.PLANT BIOCHEMIST/MOLECULAR BIOLO-

GIST: Candidates with expeience in the enzymology,secondary metabolism or ost-microbe interactions ofhigher plants, and/or molecular biology offorest trees areparticularly encouraged to apply.

Requirements: Ph.D., several years of postdoctoralexperience, and ability to develop a strong researchprogram and graduate level courses in areas of specialty.Appointments will be made at the level of assistantprofessor or higher depending on qualifications.Send curriculum vitae, a statement of research inter-

ests, and the names, addresses, and telephone numbers ofthree references by 1 March 1988 to: Dr. Michael H.Gold, Search Committee Chair, Department ofChemical and Biological Sciences, Oregon GraduateCcnter, 19600 N.W. Von Neumann Drive, Beaver-ton, OR 97006-1999. Equal Opportnity Employer.

SCIENCE, VOL. 239

The Department of Biological Process Sciences isinviting highly qualified scientists and engineers to join amultidisciplinary team responsible for fermentationprocesses involving recombinant microbial and animalcells. The Department develops cell lines, geneexpression systems, and fermentation technologiessuitable for scaling-up to pilot plant and manufacturingcapacities. Current projects are concemed with tissueplasminogen activator, second generation thrombolytics,and therapeutics for AIDS. All staff are expected toconduct self-initiated research with general applicationsas well as research which supports specific productopportunities. Department staff will be located within anew 70,000 ft2 Biopharmaceutical Pilot Facility to becommissioned later this year.The following positions are available:

Associate Senior Investigator/Cell BiologyThis scientist will conduct research in the area of theanimal cell physiology and will compliment geneticsstrategies aimed at producing high, stable expressionsystems in low serum or serum-free media suitable forlarge-scale processes. Applicants must have a Ph.D. inCell Biology or a related discipline, 1-3 years ofpostdoctoral experience, a growing publication record inareas relevant to this position, and well developedcommunication and interpersonal skills. Refer toposition #412.

Scientist/Microbial PhysiologyThis position will be concerned with the influence ofmicrobial physiology on the expression of heterologousproteins in Escherichia coli, yeast and St eptmpces infermentation reactors. Candidates must have a MS inMicrobiology or related discipline and modernfermentation equipment. Candidates with a BS and 2-3years of pertinent experience will also be considered.Refer to position #436.

Associate Scientist/FermentationTechnologyThis person will conceive and evaluate new processcontrol strategies to optimize microbial fernentationsproducing recombinant products in a state-of-the-artcomputer controlled pilot plant. Candidates must have aBS in Biochemical or Chemical Engineering includingcoursework in microbiology and biochemistry, or a BS inMicrobiology including coursework in engineeringrelated subjects. A background in process control andcomputer programming is required and experience withprocess control instrumentation is desirable. Refer toposition #17.Postdoctoral Scientist/Microbiologyor GeneticsA scientist is sought to study the production of proteasesin Streptomyces and their role in the accumulation ofrecombinant products. Candidates for this position musthave a strong research background in microbialphysiology, enzyme regulation, and/or regulation ofprotein degradation. Special consideration will be givento candidates with experience in Streotomycesphysiology. This person will work closely with membersof the Streptofivces gene expression group within theDepartment of Molecular Genetics. Our postdoctoralappointments are normally for a two year duration.Refer to position #19.Biological Process Sciences is part of theBiophannaceutical R&D Area within Smith Kline &French Laboratories, located in suburban Philadelphia,Pennsylvania. We offer excellent compensation,benefits, and relocation packages as weDl asopportunities for personal and professional growth.Please forward your C.V., the names of threereferences, and the appropriate position referencenumber to: Robert F. Obst, Manager, PersonnelRelations, R0123, Research and Development Division,P.O. Box 1539, King of Prussia, PA 19406-0939. We arean Equal Opportunity Employer, M/F/H/V.

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GRADUATEOPPORTUNITIES

In Space BiologyThe DIVISION OF BIOLOGY at KANSAS STATE UNI-VERSITY is offering an exciting opportunity for you inBIOSERVE SPACE TECHNOLOGIES, a NASA CENTERFOR THE COMMERCIAL DEVELOPMENT OF SPACE.Graduate assistantships, with an annual stipend ofS 10,200, are being awarded to qualified students forstudies that combine interests in SPACE with researchcareers in BIOLOGY

Applications are invited for graduate studies in:

* virology & oncology* microbiology & immunology* cell & developmental biology* molecular biology & genetics

* physiology & ecology

For further information write:

BIOSERVE SPACE TECHNOLOGIESDIVISION OF BIOLOGY-ACKERT HALLKANSAS STATE UNIVERSITYMANHATTAN, KS 66506

KSU is an equal opportunity/affirmative action employerh.

Your scientific creativity willearn you a spot on a top R&D team

Link your professional future to BERLEX Laboratories, agrowing pharmaceutical company and a leader inpharmaceutical R&D. This current oppty offers challenge,recognition, and generous rewards for individuals withexperience in animal models of reperfusion injury, myocardialsalvage, or infarct size determination to develop a researchprogram in cytoprotection and reduction/prevention ofmyocardial ischemia. Experience with in vivo methods incardiac electrophysiology is desirable, but not essential.

The position requires a Ph.D. with 1 or more years of relevantpost-doctoral experience. The successful applicant will havedemonstrated a high degree of scientific creativity, excellentcommunications skills, and the ability to work in a teamenvironment, supervising a small group of scientists.BERLEX provides a generous salary, comprehensive benefits,and unusual opportunities for growth. Send your CV with salaryhistory, in strict confidence, to: Attn: LILA BERNSTEIN, Manager,Human Resources R&D, BERLEX LABORATORIES, INC.,110 E. Hanover Avenue, Cedar Knolls, New Jersey 07927. EqualOpportunity Employer M/W/H.

Postdoctoral FellowSeeking a Postdoctoral Fellow to participate in the mutagen-esis and mammalian cell expression of the envelope glyco-protein of the HIV-1 retrovirus within an ongoing collabora-tive project between Dr. Phillip Berman of Genentech, Inc.and Dr. Don Wiley of Harvard Universit,v

Competence in recombinant DNA technology and an interestin protein structure are essential. Experience in proteinchemistry and/or immunology is desirable. This grant fundedposition will be available in early 1988. It is anticipated thatthe great majority of time will be spent at Genentech, Inc. inSouth San Francisco with an opportunity to also spend timeat Harvard University in Cambridge.

Please send a resume of educational background, experienceand publications, with the names of three references to: Dr.Phillip Berman, Department of Molecular Biologv and Immu-nology, Genentech, Inc., 460 Point San Bruno Blvd., SouthSan Francisco, CA 94080. An equal opportunity emplover.

Genentech, Inc.Osnsm&o%Dm(o

OAK RIDGE NATIONAL LABORATORY

The Oak Ridge National Laboratory invites nominations andapplications for the position of Director of the Laboratory.With a staff of over 4300, ORNL is the largest multiprogramenergy laboratory in the U.S. Department of Energy R&Dsystem. The Laboratory's primary missions are (1) to con-duct applied research and engineering develpment in sup-port of DOE's programs in fusion, fission, conservation, fos-sil, and other energy technologies and (2) to perform basicscientific research in selected areas of the physical and lifesciences. The Search Committee is seeking candidates whohave demonstrated management and leadership abilities anda distinguished record of achievement in scientific orengineering research. AN communications should be sent toDr. M. W. Rosenthal, Oak Rgbe National Laboratory,Building 4500N, Post Ofice Box X, Oak Ridge, TN37831-6241. All applications must be received no later thanMarch 15, 1986.

operated by

for theU.S. Department of Energy

An Equal Opportunity Employer

US. Citizenship Required (Security clearance will be required)-4

1I.

mr-

1%

Molecular BiologyResearch BS/MS

The Molecular Biology Research Group, part ofUpjohn's expanding Biotechnology program, isresponsible for conducting basic research in molecularbiology and collaborating with scientists throughoutUpjohn. We are seeking Research Associates atthe BS or MS degree levels with relevant researchexperiences, demonstrated skills in experimentaldesign, state-of-the-art analyses and interpretation ofdata for the following positions:

Mammalian Cell Molecular Biology:Experience in basic recombinant DNA techniquesand mammalian cell culture is required; a backgroundin virology studies is highly desirable; this position willinvolve research on regulation of viral geneexpression.Atherosclerosis and Thrombosis: Positionrequires a BS or MS degree in Biochemistry or relatedfield, and research experience in recombinant DNAtechniques; experience in cDNA synthesis, proteinpurification and/or mammalian cell expressiontechniques is highly desirable.Nucleotide Sequencing Analyses: Participatein collaborative DNA sequencing projects; performmanipulations of recombinant DNA and large DNA

sequencing projects, prepare data analysis usingcomputer and assist in implementation of newmethodology.Plant Molecular Biology: Develop plant genetransfer systems for crop-species; a BS or MS in plantcell biology, plant molecular biology, or other relatedarea desirable; experience in plant tissue culture andregeneration methods required; knowledge of plantmolecular biology, DNA cloning and transformationsystems helpful.Kalamazoo is located in Southwestern Michiganmidway between Chicago and Detroit and offersvaried cultural events, cosmopolitan shoppingand entertainment, lakes and woodlands minutesaway, abundant year-round sports and recreation.Upjohn offers advancement opportunities, a highlycompetitive salary commensurate with experience,comprehensive benefits and relocation assistance. Forprompt, confidential consideration, please send yourcurriculum vitae to M. William Rex, EmploymentRepresentative, The Upjohn Company, 7000Portage Road, Kalamazoo, MI 49001. Please referto advertisement number 1791-A in yourcorrespondence. An Equal Opportunity Employer,M/F.

Our Commitment to ScientificExcellence Continues...

POSITIONS OPEN

Santa Monica College is recruiting for a full-timetenure-track FACULTY POSMON to teach Astrono-my. This position requires a master's degree in astrono-my, planetary or space scicnce and a valid CaliforniaCommunity College Credential. College level teachingexpenence m astronomy lecture and laboratory courses ispreferred. Start date is 13 September 1988 with a salaryrange of $23,339 to $46,680, based upon academicpreparation and teaching expenence. Distnct applicationmust be received by March 1988. Contact: SantaMonica Coilege, Office of Personnel Services, 1900Pico Boulevard, Santa Monica, CA 90405. Tcl-phone: 213-452-9336. Equal Opportunity Employer.

FACULTY POSITIONS INMOLECULAR NEUROBIOLOGY

Applications and nominations of individuals with ac-tive research programs in molecular neurobiology arerequested for faculty positions at the full, associate, orassistant professor level. Rak and salary will be based onacademic and research record. Substantial start-up fundsand modern laboratory space are available. Excellentopportunities exist for interaction with neuroscience andmolecular biology faculty associated with formal neuro-science and genetics programs as well as from basicscience and clinical departments. Minimum requirementsinclude the Ph.D. and/or M.D. degree, and 2 years ofpostdoctoral training. Candidates should send acrricu-lum vitae, a description of research activities, repre-sentative reprints, and the names of three or morereferences to:

Dr. Peter GcttingDepartment of Physiology and Biophysics

The University of IowaIowa City, IA 52242

GROWTH FACTORSRESEARCH AND DEVELOPMENT

Otisville BioPharm, a growth-oriented company, hasthe following challenging positions availablc in the fieldof:CELL BIOLOGIST-Senior position. Anplicant

should have extensive experience in mammalian cellculture, with hematopoietic and tumor cells.QUALITY CONTROL AND ASSURANCE SU-

PERVISOR-Must be experienced in virus, mycoplas-ma detection and GMPs.BIOCHEMICAL RESEARCH ASSISTANT-

Must be experienced in biochemical techniques, chroma-tography and electrophoresis.

Otisville BioPharm, Inc.P.O. Box 567

Otisvile, NY 10963914-386-2891

IMMUNOLOGISTTenure-track assistant professorship anticipated begin-

ning August 1988. The Ph.D. degree is required inimmunology, or cellular immunology with postdoctoralexperienced favored. The individual will be expccted todevelop a research and graduate program within somearea modern immunology and teach an undergraduateand graduate course in immunology. A commitment toexcellence in research and teaching is required. To assurefiull consideration, send curriculum vitae, statement ofresearch goals, and the names of three references by 1April 1988 to: Dr. Glenn Todd, Head, Department ofBotany and Microbiology, Oklahoma State Universi-ty, Stillwater, OK 74078. An Equal OpportunitylAffir-mati Action Employr.

INSTRUCTOR IN MEDICINE needed to designand conduct kinetic experiments of photobleaching ofnucleic acids, fluorescent dyes and chromosomes; writeand validate computer programs in Fortran and C formulti-compartment, multi-component kinetic analysis;formulate mathematical models of kinetic processes andtest these theories by computer simulation and statisticalerror analysis. Instruct postdoctoral fellows and graduatestudents m usage of digital imaging data processingsoftware. Must have Ph.D. degree in chemistry, with 2years of experience in research in chemistry and appliedmathematics. Salary $28,080 per year; 40 hours perweek. Apply at: The Texas Employment Commission,Houston, TX, or send r&sume to: Thc Texas Employ-ment Commission, TEC Building, Austin, TX 78778,J.O. #4422587. Ad paid by an Equal Employment Op-portunity Employer.

822

POSITIONS OPEN

HARRINGTON CANCER CENTERIMMUNOLOGY POSMONS

The Harrington Cancer Center, a non-profit, ambula-tory treatment center located in Amarillo, Texas is ex-panding its research capability, and anticipates two posi-ions i the area ofmolecular immunology. One positionwould be an upper level (equivalent to an assistant orassociate professor) for an individual experienced in flowcytometry. This position would include responsibility forrunning the dinical flow cytometry laboratory in addi-tion to initiating an independent research program. Thesecond position would be for an individual at the post-doctoral level, and would be for research in the area ofmonoclonal antibodies directed against B cell tumors.These individuals will join an already established immu-nology group at the Harnington Center, The Texas TechRegional Academic Health Sciences Center and theAmarillo Vaetrans' Administration Hospital.To apply for these positions, please send curriculum

vitae to:Dr. K. John Morrow, Jr.

Department of BiochemistryTexas Tech lJniversity Health Sciences Center

Lubbock, TX 79430

MRI/MRS EDUCATIONAL DIRECTOR. TheDepartment of Radiology of the Hospital of the Univer-sity of Pennsylvania is seeking applicants for a facultyposition as Director ofMR Education in the Departmentof Radiology. This individual will direct ongoing con-tinuing education programs in magnetic resonance imag-ing and sproscopy for physicians and technologists,and will also have the opportuity to pursue an activeresearch program in MRI/MRS. Applicants should havcdemonstrated research and teaching experience in MRI/MRS, as well as outstanding written and verbal commu-nication skills. Rank and salary commensurate withexprience. Send curriculum vitae to: Herbert Y. Krcs-

scl M.D., Chief, Magneic Resonance Imagng, Hos-pital of the University of Pennsylvania, 340 SpruceStreet, Philadelphia, PA 19104. The Uniemy ofPenn-sylvania is an Equal OpportunieylAffinnative Action Em-ployer. Qualfiedfma and minority candidate are encur-aged to apply.

MANAGER, PILOT PLANT,PENN STATE

BIOTECHNOLOGY INSTITUTEThe Penn State University seeks an individual to

supervise the design, construction, and operation of amajor new pilot pEt as part of the expanding activitiesof its Biotechnology Institute. Individual will report tothe institute director, but will have the ability to workindependently with architects, equipment manufacturersand users from the university and private sector. Experi-ence in design and operation of pilot plants and processdevelopment is required. Experience with scale-up ofbiological processes, especialy genetically engineeredcells, preferred. Supervisory experience desirable. Sendapplication letter and resume to: Dr. Jean E. Brencbley,Director, Penn State Biotechnolo Institute, 519ABiotechnology Headquartm Building, UniversityPark, PA 16802. Review of applications will begin 15March 1988 and continue untit the position is filled. AnEqual Opportunity/AffinmativeActiom Employer.

MEDICAL DIRECTORPosition immediately available for M.D./Ph.D. to head

clinical evaluation program of new diagnostic agents fora subsidiary of a major worldwide manufacturer ofmedical products. Please forward curriculum vitae to: M.Sovak, M.D., 3333 North Torrey Pines Court #100,La Jolla, CA 92037.

MICROSCOPIC ANATOMIST OR VETERI-NARY PATHOLOGIST/TOXICOLOGIST. Ph.D.or D.V.M./Ph.D. to teach microscopic anatomy anddevelop an extramurally funded research program. Sendletter, resume, and names of three references: N. E.Hutton, Veterinary Medicine, Oregon State Universi-ty, Corvallis, OR 97331, before 15March 1988. EqualEmplyment OpprtnstylAffirmatiActionEmployer, com-plies Secaion 504 RehabilitationActof1973 and rsapoive todua-car couple.

POSITIONS OPEN

The Centers for Disease Control is seeking a MEDI-CAL VIROLOGIST with M.D. or equivalent degreeto work with biosafety level 4 viruses (mduding Lassa,Ebola, Marburg, Congo Crimean hemorrhagic fever andHantaan viruses) in a Maximum Containment Labora-tory and under field conditions. Must have a minimum of3 years of laboratory experience in virology including 2years ofworking with biosafety level 4 viruses, indudingisolation and purification of viruses, as well as experiencein designing and conducting experiments on diseasepathogenesis, utilizingrrent concepts and tcchniquesin virology, immunology, hematology, and physiologyunder biosafety level 4 conditions. Must have at least 1year of dimcal and epidemiologic experience with viralhemorrhagic fevers incuding therapy and study ofpathophysiology of disease in humans. Must be willingto travel internationally in order to organixe and conductepidemic investigations, set up field and clinical studiesin remote areas. Must be able to direct laboratory groupon studics ofd4iaosis, immunology and pathogenesis ofviral hemorrhagic fevers, and have expenence in evalua-tion of vaccines in primates. Fluency in French and atleast one other foreign languagc is highly desirable.Preferred candidates should have an earned doctoraldegree (M.D., Ph.D. or equivalent) and a record ofdistinguished service resarc'h. Salary level $45,763 to$50,338, commensurate with experience. Interested ap-plicants should submit curriculum vitae and names ofthree professional references to: Sharlyn Wilkinson,Personnl Management Office, Room 1058, Centefor Disease Control, 1600 Clifton Road, Atlanta, GA30333. Telephonc: 404-639-3274. CDC is an EqualOpportunity Employer and pnride a smoke-fiee work envi-ronment.

MOLECULAR BIOLOGISTThe Research Division ofHenry Ford Hospital invites

applications for the position ofsenior staffinvestigator inmolecular biology. Persons interested in oncogene regu-lation or transplantation immunology are particuladrlyencouraged to apply, although strong applications usingmolecular biological approaches in research areas broadlyrelated to human diseasc will be considered. Substantialresources will be available including the possibility ofacademic affiliations.

Applicants should have completed several years ofpostdoctoral study, and will be expected to develop astrong research program capable of attracting extramuralfunding. Curriculum vitae and the names of three refer-ences should be sent to:

Dr. Leonard C. Lutter, ChairmanMoloular Biology Search Committoe

Research DivisionHenry Ford Hospital

2799 West Grand BoulevardDetroit, MI 48202

MOLECULAR BIOLOGISTThe Division of Rheumatology, Departnent ofMedi-

cine, at the University of Colorado Health SciencesCenter, invites applications for a position at the begin-ning faculty leve. Applicants should have completed atleast 2 years of postdoctoral work with experience in theregulation of gene expression. The position is full-timeresearch in a laboratory interested in regulation of syn-thesis ofinterleukin 1 in human monocytes. The positionis availble in 1988 with applications considered throughthe end of April. Salary and start-up funds willprovided but appointee will be expected to partici-pate in applying for rcsearch support. Plcase submitcurriculum vitae, summary of research experiences, and alist of four references to: William P. Arend, M.D.,Profcssor and Head, Division ofRhoumatology, Uni-versity of Colorado Health Sciences Center, BoxB115, 4200 East Ninth Avenue, Denver, CO 80262.The Univety of Corado is an Affiwmative Action/EqualOppornunity Employer.

MOLECULAR BIOLOGY RESEARCH TECH-NICIAN-B.S./M.S. or equivalent, with experience inplant transformation, regulation ofgene expression, genedoning and/or vector construction. Emphasis on tissue-specific and developmentally regulated exprcssion offoreign genes in plants with the long-term goal of cropimprovement. Send resume and three references to: Dr.Gary Hufnian Department of Biotechnology Re-search, Pioneer Hi-Bred International, Box 38, John-ston, IA 50131. An Equl OpportunityAffirmative Ac-tion Employr.

SCIENCE, VOL. 239

POSITIONS OPEN

MOLECULAR GNETICIST (M.D. or M.D.-Ph.D.) wanted as Chief of new Genetics Division in theDepartmn of Pediatics of Case Wester Reserve Uni-versity Schol of Medic at Raibo Babies amdChildrens HospitaL Imbewill be expectd wo devel-op and recuit addiional re-seachpcw compleientsart stegh in epi-ialg amlbiabp, qsiic ff i muog andnonat lm ito face with sciene de-parn Preference will bc gven to a dinaly inedphsician-scientist who develop rearci

oitsnmecular gencs within the -met of Pediatrics. Faculty rank/salary commensuratewith xp c. 5 a _inxwmben ar St Ce IL Beger,M.D,Ph.DDD MofP,&2tcswW enResrve Unisi oodi, 2074 Abig-ton Rod,m Clevnd, OH 44106. Teleo 216844-3237. CWRU isan Eq OAaim Employcr.

MOLECULAI GENTICISTPostdoctoratl p aib imdi o studygS invohled in siter chrmatid recmbonatin andnhvmqce- n in. Dv E ien

gentcs and b desired n c ivite aid names of r refreics to: Dr. Sbr7Eno;, OfS1k.1 DUcMaldEl Ce, h NC 277MDt*ap Eqw B.Ps)~~xk

MOLECULAR GENETICISTYAL SCHOOL OF ICINE

The Deparment of Human Gemeics ivite appica-tions for a posit as an assstant professor, a tenure-a positin wih ecdn l o fa , in asimuigenvironment. We c who have aPh.D. orM.D. degree, a record of _h in

researchinest,and toarrage t have the aetesoprgam reerh at< ied

in de d to apply-

ro nt set to:Dr. Charn AL Raddng

airman, Faculty Search CmitDe~mrtuentf HmanGenetics

School ofMedicP.O.B 3333

New Haven, Cr 06510Applications should be sumited befire 31 March

1988. Yak Uusmnisy ir as Equa OpwemudylAjinpuazfAauo Empkycr.

MOLECULAR VIROL1GST. Tenure-tra as-sstant proessor on amibe after 1 July 1988.

rescarhsinterests in virology atthe molcular biology lev RmibiLiiesihecon-tribution to effort ad patipa-t in a jomt wit thc SdhooofMdkinc.U Ibe wbaDis1amin

sumAmm rse ad _ rcompCe fo fi-mpport.Apphcan should curricuuiey

Tell-licai, D_ ~Of PittbbuPi-bb,PA1261. Cbsng d lb po isr-Ap1988.~~~~ ~dtl*cIrE ~ 0

NEUROPHARMACOLOGY FACULTY POSI-TION: The D ment ofP amcol at New YorkMedical Colf appi o ir an assistant orass e pros,tenure-track p4 Apl ssould have an M.D. or Ph.D. dere in ph ,biohemistry, siology cell or in a reedfildd,and abilrtvrto decop Pan research

try, moklular and ceal t the invga of'prokin --D.Pex-w-ardl hah ,aitof pu nedence--t, s by 30Mad 1988 to: M. eGzzDe,

andnnu, Ofrtn ef c -ogy,NewYorkMedi lCge,Valafla,NY 10595.

I2 FEBRUARY 1988

U.S. PATENT AND TRADEMARK OFFICEPOSmON: MicrobiologisVPatent Examiner Opportunity in-volves the scientific and legal evaluation of patent applica-tions involving recombinant DNA, molecular and cellularimmunology, molecular genetics, microorganisms, cell biolo-gy, cell culture, fermentation, enzymology or clinicalchemistry.QUALIFICATIONS: A full 4-year or longer professional curric-ulum in an accredited college or university leading to aBachelor's Degree or higher with specific study in MolecularBiology, Biochemistry, Immunology, Enzymology, Embryolo-gy, Protein Chemistry, Microbiology or Cell Biology.A Ph.D. or M.S. degree with relevant research experience ispreferred. A B.S. degree with significant research experiencewill be considered.Research Experience in any of the following areas would bebeneficial: DNA cloning, protein chemistry, gene expression,sequencing techniques, muteins, hybridoma technologies,monoclonal antibody applications, mammalian or plant celllines, cell culture, immunossays, hybridization techniques,fermentation, enzymatic reaction, diagnostics and automationof clinical analysis.SALARY: Dependent upon experience and qualifications.LOCATION OF POSmON: Arlington, VAFor further information contact:

Patent and Trademark OfficeOffice of Personnel, C&ECPK 1, Suite 700Washington, D.C. 20231703-557-3631Toll free: 800-368-3064

BERGER ItNGELHE"I d'vlPmn~nc.,an~Iovator in the researc. deves anOPent

and. ~a lretnno ethical drugs5 cuirrentl? has loanted*nd marktou esearth an eeopmen aiiY oaeinaor ''Cct4ECTICUT eVna

Thea(Mf Cemistry Departiment, in a-TeAnalYtical C astrong backgrOun inth

?h..lve ScentstWith andustrial e)(perleneithPhD eelSince and ofmd ncoaatbdeBioanalytica, cesig Srn ete

release and stabilitY testn ofpronuctsonas arvntleodierand related V prodchngowritteand oral cmrnUnasstfr ahsPeos' proTenALeaership skills ae a

~ Elm PV-4ARMAnCenftBOEFVIp,1NGERING EL n adbnfton.ffers a com Staence and theo

pack,age. relocao asr~c0g96ed thav contribu'Cons edyuFor confidenti deIo. snd.you

'-- f.leot. 1C IS. 90

RESEARCHTOXICOLOGIST

Alcon Laboratories is a $500 million multinational phar-maceutical company and the recognized industry leader inophthalmic research. The growth of our basic researchgroup has created an Immediate requirement for a SeniorScientist within our Research Toxicology Section. Thisposition will take a leading role in the design and conductof studies investigating biochemical and cellular mecha-nisms of toxicity of drug candidates and therapeuticmodalities.

Requirements include:

* Ph.D. in Toxicology or related discipline* Postdoctoral and research experience in in vitro

techniques, xenobiotic metabolism or oxidativemechanisms of tissue injury highly desirable

* Good oral/written communication skills

This position offers an excellent opportunity for profes-sional recognition and career growth. We offer a com-petitive starting salary, company paid benefits, an ex-cellent profit sharing plan, and a desirable Fort Worth loca-tion with numerous recreational, cultural, and economicadvantages. If you are seeking a career opportunity in-volving challenging work within a dynamic, state-of-the-art research environment, please send resume with salaryhistory to: Sherry H. RIghtmer, Employment Supervisor,Alcon Laboratories, Inc., P.O. Box 6600, Ft. Worth, TX76115.

Equal Opportunity Employer, M/F/V/H * Principals Only. Please

_~~ kE]U I

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICS ABOUT YOUR PROPOSEDLAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1I515 BROADWAYNEW YORK, N.Y. 10036

m

BACTERIAL GENETICS-MOLECULAR BIOLOGY

EG&G Idaho, Inc., Prime Operating Contractor for theDepartment of Energy's Idaho National Engineering Lab-oratory has a Staff/Postdoctoral position available in itsBiotechnology Group. Qualifications should include labora-tory experience with most or all of the following: methods ofbacterial identification/classification, mutant production andcharacterization, bacterial mating/strain construction, bac-teriophage isolation and manipulation, plasmid and chrom-somal DNA isolation and characterization, nucleic acidhybridization, recombinant DNA techniques/cloning, micro-organism transformation, DNA sequencing. Experience withenvironmental microbes would be advantageous but is notessential.The Biotechnology Group studies the capabilities of a varietyof environmental microorganisms and the application ofthose capabilities to problems in energy, materials, wastemanagement, etc. The Group and its programs are steadilyexpanding. Their laboratories are located in the INELResearch Center, a newly completed 50,000 sq. ft. facilitylocated in Idaho Falls. This facility also houses researchgroups in chemistry, physics, environmental sciences,advanced materials, etc. This high technology environment islocated within easy reach of several major year-aroundoutdoor recreation areas, including some of the largestremaining wilderness areas in the U.S.We offer a competitive salary and benefits package. Positionand salary will be commensurate with qualifications andexperience. Please send your resume, references and salaryhistory to: Employment Services, (HD-38), EG&G Idaho, Inc.,P.O. Box 1625, Idaho Falls, Idaho 83415. We are an equalopportunity employer M / F / H/V. U.S. Citizenship required.

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BIO-RAD LABORATORIES is a worldwideleader in the fields of clinical diagnostics,chemical separations and analytical instrumen-tation. Our Clinical Diagnostics Division is con-tinuing to expand in order to undertake thedevelopment of new immunoassay systems forthe 1990s. We are looking for motivated, goal-oriented professionals with experience in thefollowing areas:

Business Unit ManagerThis leadership position is responsible for theresearch and development, and marketingactivities for major product lines both existingand planned. These responsibilities include thechallenge of providing general managementdirection to a strong team of talented researchand marketing professionals. Experience indiagnostics or a related health industry with atechnical education is desired along with theability to plan and implement product/marketingstrategies.

Research andDevelopment ManagerYou will need 5 or more years' experience indiagnostics with at least 3 years of projectmanagement. Excellent people skills and thedemonstrated ability to manage multidisciplin-ary teams are essential.Marketing, service, and a strong customer ori-entation are part of the culture and directionwe desire for these positions.We also have a variety of positions availablein immunoassay development, microbiol-ogy, and instrumentation engineering.

Be part of the team in our new facilitiesoverlooking the Bay in Hercules,California.

For consideration, please submit resume toBio-Rad Laboratories, Human Resources,Dept. #293-S0212, 1000 Alfred Nobel Drive,Hercules, CA 94547. EOE.

Laboratories

THE INTERNATIONAL RICE RESEARCH INSTITUTE (IRRI)SEEKS A DEPUTY DIRECTOR GENERAL

FOR RESEARCHRESPONSIBILITIES:* Provide leadership in multidisciplinary research among scientists in various agrcul-

tural disciplines from both developed and developing countries.* Develop, budget, monitor, and evaluate research conducted within a decentralized

management structure* Establish and maintain collaborative research programs that complement those of

national agricultural research systems in rice-growing countries

QUALIFICATIONS:* PhD in agricultural or biological sciences with excellent scientific record and

recognition* Demonstrated vision and experience in the planning and accomplishment of

interdisciplinary research* Ability to motivate an internationally recruited staff from different cultural, and social,

and scientific backgrounds* Extensive experience in administrative and financial management* Experience in international collaborative research, both with national agncultural

research systems in rice-growing countries and advanced institutesThe deputy director general for research will live at IRRI headquarters on the campus ofThe University of the Philippines, Los Banos-60 km south of manila. Substantialintemational travel will be required. The salary and benefits will be commensurate withsalaries and benefits of similar intemational institutes and programs in agriculture.IRRI is an intemational, non-profit, agrcultural research institute funded by about 30donor nations and organizations. IRRI conducts research on the rice plant and on allphases of rice production, management, distrbution, and utilization. Its goal is toenhance rce production and sustainability to benefit the more than one billion people inthe worid who are dependent on rice for their livelihood and as their basic food.Applications due: 30 March 1988Submit curriculum vitae and the names of three references to:

Dr. Klaus J. Lamps, Director General-DesignateIRRIP.O. Box 933Manila, Philippines

Reply to U.S. Telex no. 4900009251 (49000092511RR UI)

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POSITIONS OPEN

NEUROBIOLOGY-POSTDOCTORAL ASSOCIATES

Two openings are now available in the laboratory ofDr. Robert O'Connell to study Olfactory Ncurobiolo-gy. One position seeks to explore olfactory transductionat the membrane level. This research involves biophysicaland biochemical approaches to the molecular mecha-nisms responsible tor pheromone detection in insectolfactory receptor neurons. Experience with either mem-brane reconstitution, second messenger system biochem-istry or single-channcl recording techniques is required.The second position seeks to explore mechanisms ofolfactory communication at several levels. The plannedresearch involves a multidisciplinary approach to theanatomical, behavioral, chemical, electrophysiological,and hormonal substrates of olfactory communication inseveral mammalian species. Experience in one or more ofthese areas is required. Salaries are commensurate withexperience. The Worcester Foundation is situated on awooded 100-acre campus only a few minutes from theMedical School and other universities in Worcester andin close proximity to Boston, Hartford, and Providencearea academic and research institutions. Send curriculumvitae, a statement of past research interests, and thenames ofat least three references to: Dr. Robert O'Con-nell, c/o Personnel Office, Worcester Foundation fbrExperimental Biology, 222 Maple Avenue, Shrews-bury, MA 01545.An Equal Oppotna yAfinwa6veAaion Emplk)erMFIH.

ORGANIC SYNTHETIC CHEMISTSubsidiary of the Cook Group of Companies, world-

wide medical technology manufacturers, seeks an cxperi-enced, dynamic Ph.D. to lead an exciting research group,primarily but not exclusively focused on diagnostic drugssuch as radiographic contrast media. Competitive salaryand benefits. Please forward resume with statement ofavailability to: Cook Imaging, 3333 North TorreyPines Court, #100, La Jolla, CA 92037.

PHYSICAL CHEMIST-Williams College has anopening for a tenure-track position in physical chemistryfor fall 1988 (Ph.D. required; postdoctoral experiencepreferred). Applicants should have a strong commitmentto both teaching and research. Teaching assignments willencompass physical chemistry courses and other coursesin the chemistry curriculum consistent with the person'sbackground and interests. A semester teaching loadnormally includes complete responsibility fbr one coursewith laboratory and supervision of senior research pro-jects. Williams College is a highly selective, coeducation-al, liberal arts institution of approximately 165 faculty,1950 undergraduates, and 25 to 35 chemistry majorseach year, located in northwestem Massachusetts. TheChemistry Department is accredited by the ACS, and hasexcellent facilities for teaching and research. Send resu-me, undergraduate and graduate transcripts, descriptionof research interests for undergraduates, and names ofthree references to: Dr. James P. Skdnner, Chairman,Department of Chemistry, Williams College, Wil-liamstown, MA 01267, by 11 March 1988. EqualOpporunitylAffirmativeAtion Employer. We are especiallyintcrcstcd in identifing minority and women candidates.

PLANT PHYSIOLOGIST. The Department of Bi-ology at Trinity University invites applications for atenure-track faculty position at the assistant professorlevel available August 1988. Candidates must have aPh.D. in biology with a preference given to persons witha speciality in plant physiology or plant cellular andmolcular biology. Duties include the development of alecture and laboratory course in the area of specialty,participation in core courses for majors, and academicadvising. The successful candidate will be expected toestablish a vigorous research program in one of thefollowing areas: cellular/molecular biology, developmen-tal genetics, comparative physiology, embryogenesis, orecological physiology of plants. Salary will be commen-surate with education and experience. Trinity Universityis a private, primarily undergraduate 4-year liberal artsand sciences institution of 2600 students. Applicantsshould send curriculum vitae, summary of research expe-rience and interests, and names of three references to:Professor Thomas L. Koppenheffir, Chairman, De-partment of Biology, Trinity University, San Anto-nio, TX 78284. Application deadline is 7 March 1988.Trnity Unweiety u an Equal OpportunitylAffirmativeAction Employer.

826

CIBA-GEIGY PharmaceuticalsCIBA-GEIGY, a leader in pharmaceutical research, currently has a uniqueopportunity available at the Summit, New Jersey, Division headquarters.Candidates will participate in an innovative, multidisciplinary effort targetedat the rational design of receptor antagonists. A recent PhD in MolecularBiology or a related area and experience with gene expression and muta-genesis are required. An interest in protein structure is preferred.At CIBA-GEIGY, you'll find a stimulating environment offering competitivesalaries, excellent benefits and an ideal opportunity to grow both personallyand professionally. Please send your resume, in confidence, to: Ms. SandraLatzer, Dept. SL, The Pharmaceuticals Division, CIBA-GEIGY Corporation,556 Morris Avenue, Summit, NJ 07901. We are an equal opportunity em-

ployer in/f/h/v.

Science Serving Mankind

CIBA GEIGY

Sr. ScientistlSectionLeader Microbiology

SANDOZ CROP PROTECTION CORPORA-TION, a company widely recognized for excel-lence in agricultural research and manufactur-ing, has an opening for a Microbiologist as Sr.Scientist/Section Leader in Biological Devel-opment. The function of this position will be todirect fermentation development for MicrobialInsecticides. Requirements include:

* Ph. D. in Microbiology with minor inBiochemstry and/or immunology

* At least 5 years experience in Microbialphysiology research with bacterialcultures and 2 years fermentabonprocess development.

* Skills in modern biotechnologytechniques desired.

For consideration send resume to:

SANDOZ CROP PROTECTION CORP.Denise WileyP.O. Box 220Wasco, CA 93280

EEO/AA

PHARMACOLOGISTINFLAMMATIONIMMUNOLOGY

Ph.D. level with a minimum of 3 yearsindustrial experience in Inflammation/Immunomodulation drug discovery.Knowledge of in vivo and in vitromodels of disease highly desirable. Ahigh energy level and a strong knowl-edge of the relevant literature is essen-tial. Our team employs the very latest incomputer assisted drug design tech-nology, by utilizing the Computer Auto-mated Structure Evaluation (CASE)program. We are looking for a phar-macologist who will work closely withour theoretical and synthetic chemists,using artificial intelligence techniquesto identify new chemical eritities. If anopportunity for self-direction and sci-entific leadership is appealing, pleaseapply.BIOFOR, INC. is located in North-eastern Pennsylvania near the beauti-ful Pocono Mountains. We offer oppor-tunity for substantial growth. All in-quiries will remain confidential.Send resume to:

BIOFOR, INC.P.O. Box 577Waverly, PA 18471

SENIOR MICROBIOLOGISTS

Rohm and Haas Company, a Fortune 200 manufacturer of specialty chemicals for industryand agriculture, has several immediate openings for Senior Microbiologists in the BiocidesResearch Department. These positions are at our Corporate Research Center in SpringHouse, PA twenty miles north of center-city Philadelphia. They represent significantgrowth in our commitment to develop leading biocidestoaddtoourKathon@ product lines.

SENIOR MICROBIOLOGIST:Applications Research

Ph.D. or experienced M.S. microbiologistwith extensive experience in:

Water Treatment* Cooling towers* Paper making* Oil production

orPreservatives

* Metalworking fluids* Cosmetics* Consumer products

This scientist will be responsible for researchto determine how best to use antimicrobialcompounds (biocides) in a variety of indus-trially important products and processes.

SENIOR MICROBIOLOGIST:Biocides Evaluation

Ph.D. or experienced M.S. microbiologist,with extensive knowledge of screening andevaluating biocidal candidates for commer-cial applications.Responsibilities involve integrating ourscreening operations to facilitate selection ofcandidate biocides for applications testingand development, and reporting evaluationsto management.

SENIOR MICROBIOLOGIST:Microbial Physiology

Ph.D. microbiologist, with emphasis inmicrobial physiology or microbial ecology.Research projects include:

* Determining the mechanisms of actionof selected antimicrobial agents.

* Investigating the ability of microorgan-isms to develop resistance to selectedantimicrobial agents in specific indus-trial applications.

No previous industrial experience requiredfor this position.

SENIOR MICROBIOLOGIST:Biodeterioration Mycology

Ph.D. or experienced M.S. scientist withexperience in fungal biodeterioration. Thisscientist will work in our applied mycologygroup on projects toestablish how bestto usebiocides to prevent fungal damage. Applica-tions that the group is currently investigatinginclude:

* Wood degradation* Plastics* Paints and coatings* Textiles* Distillate fuels

Besides superior technical accomplishments, successful candidates must exhibit excel-lent written and oral communication. Also important are thoseorganizational and interper-sonal skills that ease effective collaboration with scientists of otherdisciplines. Candidatesshould be U.S. citizens or permanent residents.Rohm and Haas offers a highly competitive salary and benefits program, includingrelocation assistance. Our staff enjoys modern research facilities, a high investment inresearch, and outstanding analytical support. There are many opportunities for profes-sional development and, whenever possible, we promote from within.Please send your resume, including three professional references, in confidence, to:

Corporate Staffing #888

ROHMIEPHILADELPHIA, PA. 19105

An Equal Opportunity Employer M/F.

A postdoctoral Visiting Scientist position isable within the MedicalProducts Department

at Du Pont's Experimental Station in Wllmington,Delaware. The successful candidate will conductbasic research on the renin-angiotensin system,angiotensin II receptor. Candidates should have astrong backgound in cardiovascular, renal and/ormolecular pharmacology. The appointment will befor one year, renewable for a second year uponmutual agreement.

At the world renowned Du Pont Company,youll find a highly stimulating multidisciplinaryresearch environment in addition to an excellentsalary. To be considered, please send your resume,bibliography, and references to: Dr. Stephen T. Toy,Employee Relations Department, Room X51005, DuPont Company, Wilmington, Delaware 19898.

( ~ f ~ ) U.S. Citizenship RequiredAn Equal Opportunitv

"C. OF"Employer M/F/H/V

*,c us .t . .

UNDERGRADUATERESEARCH

The U.S. Department of Energy offerscollege juniors and seniors theopportunity to do research at five federallaboratories. Qualified students spendone academic term in energy-relatedresearch at the frontier of science withstate-of-the-art facilities and equipment.

BENEFITS* Stipends up to $175 per

week* Round-trip travel and

housing* Academic credit may be

arranged through thehome institution

* Research Areas include:computer sciences,engineering, environmentala life scences.mathematics, and physicalsciences

For detailed information and applicationforms, please write to this address:Science and Engineering Research Semester

U.S. Department of EnergyOffice of Energy Research, Room 3F-061

1000 In ce Avenue, SWWashington, D.C. 20585

Application Deadline: March 15, 1988

TENURE TRACK STAFFPOSITIONS AT THE

BIOLOGICAL RESPONSEMODIFIERS PROGRAM, NCI

The Clinical Research Branch, Biological Response Modifiers Pro-gram, Division of Cancer Treatment, the National Cancer Institute,National Institutes of Health, Public Health Service, is accepting ap-plications for two staff positions. Positions are available to physi-cians who are either Board eligible or Board certified in medical on-cology.

The incumbent will be responsible for primary patient care and thedesign and conduct of clinical trials utilizing biological responsemodifiers. Emphasis is also placed on continuity of patient care,principles of patient management, and correlation of clinicalresponse with changes in immunologic parameters.

Staff Fellows will be assigned to Civil Service positions with an an-nual salary between $24,000 and $49,266 (based upon experience)and an increase up to $1,500 for each additional year up to a max-imum of $49,266. Staff Fellows are eligible for all benefits includinghealth insurance, life insurance options, vacation, and sick leave. Inaddition, travel expenses for the Fellow to his duty station areavailable.

For further information and application procedures, please contact:

Ronald G. Steis, M.D.Medical Pavilion,Frederick Memorial Hospital335 Park AvenueFrederick, Maryland 21701(301) 698-5929U.S. CITIZENSHIP ORPERMANENT RESIDENCY REQUIREDAN NIH ASSOCIATE TRAINING PROGRAMNIH IS AN EQUAL OPPORTUNITY EMPLOYERDeadline for applications is March 15, 1988.

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VETERINARY

PATHOLOGIST

4W're Caring For the Wbrld:Join A leading Subsidiary of

ETHICON, INC., the world's leader in woundclosure development seeks an experienced Tox-icologic Pathologist to participate in wound heal-ing research and the safety assessment ofwoundhealing pharmaceuticals and devices.

This position requires a DVM Pathologist with aminimum of 3 years experience in toxicologicpathology associated with drug development.The ideal candidate will have ACVP board cer-tification ortrainingappropriatetositforthe boardexamination.

Excel lent verbal and written communication ski Isare required. Send resume orCV to: Mr. Walter L.

Pino, Employment Manager

ETH I CO 1Na Company

Route 22, Somerville, NJ 08876

A Corporation With a ConscienceEqual Opportunity Employer M/F

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Several B.S. or M.S. Degree level positions in chemistry and biochemistry with 0-5 years of experience are availablewithin the PharmaceuticalsOivision of our Medical Products Department.

Process Development Chemist: This position involves developing processes for the preparationof our bulk pharmaceuticaTs and drug candidates. Responsibilities indude both lab syntheses and support of Semiworkscampaigns to produce material for the pre-Clinical and Clinical studies. The qualified candidate will have extensiveknowledge and interest in organic synthesis, experience in purifying and characterizing organic compounds and theability to communicate well in a team environment. Experience with Good Manufactunng Practices is a definite plus.

Process Development Biochemist: This position involves developing processes for the prepara-tion of biological materialsTr pre-Cinical, Clinical and Diagnostic studies. Responsibilities indude laboratory and scale-upprograms for the production of large quantities of these biotechnology compounds. The qualified candidate will havean excelelnt command of biochemistry induding practical experience with extraction, purfcation and characterizationof proteins and nudeic acids. Excellent oral and written communication skills are required to work on this multidisciplinaryteam. Experience with FDA regulation, particularly Good Manufacturing Practices, is a definite plus.You will find a highly stimulating scientific environment in a modern research facility located near Wilmington, Delaware.We offer excellent compensation and benefits, including relocation. Our mid Atlantic location offers an attractive life-style with easy access to a wide-range of academic, cultural and recreational activities. Candidates should send theirresumes and references, indicating positions of interest, to: Professional Staffing, Employee Relations Department, RoomX51038, Du Pont Company, Wilmington, Delaware 19898.

An Eual rtunity Employer M/FIHIVU.S. titizensipRequired

ftc us * -w

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Develop DesktopMedical Diagnostics

Imagine taking the capabilities of a hospital laboratoryright to the patient's bedside or into the office of anydoctor anywhere. New technology from MolecularDevices will do just that, merging microelectronics andbiochemistry to create a powerful portable medical diag-nostic system. Explore the following openings:

Development MicrobiologistDevelop immunoassays for microbial systems (includingSTDs), screen appropriate antibodies, and design novelreagent formats.

Development ChemistDevelop diagnostic procedures using expertise of gen-eral clinical chemistries, particularly in area of lipiddetermination.Both positions require a PhD (or equivalent) with 5 years'demonstrated hands-on experience.Send your resume to Professional Staffing, MolecularDevices Corporation, 3180 Porter Drive, Palo Alto, CA94303. An equal opportunity employer.

Molecular

Industrial PostdoctoralPosition:

Human Model Systemsin Toxcology

The Environmental Health Laboratory of Monsanto AgriculturalCompany, located in St. Louis, Missouri, is seeking a PostdoctoralScientist to participate in toxicology research aimed to developexperimental systems to predict human toxicity.The successful candidate will participate in our ongoing researchprogram on the validation of cultural hepatocytes as anexperimental system to study species companson of chemicaltoxicity. Hepatocytes cultured from human and other animalspecies will be studied. The candidate may also participate inthe development of other relevant experimental models to predicthuman toxicity of chemicals.Candidates are required to have a Ph.D. in Cell Biology,Biochemistry, Toxicology or other related disciplines, andexperience in hepatocyte cultures and measurement ofxenobiotic metabolism.This position is renewable on an annual basis with an anticipatedduration of 2 years. Extemal publications and participation inthe scientific community will be encouraged.Monsanto provides a generous compensation package relativeto your responsibilities and qualifications. Interested candidates,please forward your resume to: Vemon L Bozarth; Mal ZoneB3N&; MONSANTO COMPANY; 800 N. Undbergh Blvd.; StLouis, MO 63167. An Equal Opportunity Employer

M/F/H/V.

0

1-m-M iii9

POSITIONS OPEN

PHYSIOLOGY POSMONPHYSIOLOGIST: A tenure-track position at the

level of assistant professor is anticipated Au-gust 1988. An carned doctorate is equired with pOSt-

doctoral experience preferred. The successful applicant

will be expected to develop a vigorous rescarch programand supervise graduate students. Teaching responsibil-ities wil incude upper division courses in human ph i-

ology, including neurobiology, and possibly introduc-tory biochemistry. Submit a letter ofapplication, curricu-

lum vitae, and official transcripts, and have tree lettcrsof reference sent to: Physiolovy Section Committee,Department of Biological Scnces, Idaho Ste Uni-very, Pocateilo, ID 83209. Dcadlinc 15 March 1988.Idaho State Uniersty is an Equal Opportunity Emplyer.

PIANT ECOLOGISTThe Dcpartment ofEcology and Evolutionary Biology

at the University ofConnecticut invites applications for atenure-track assistant professorship in plant ecology atthe Hartford Regional campus to begi in Scptember1988.The successful candidate will be.expected to develop a

vigorous research program, and to teach beginning andadvanced undergraduate courses in biolog and wil have

ampl opportunitics to intcract with collagues at thenearby main campus on a recular basis. We will provide

an office at the main campus m addition to facilities at theHartford campus. Applicants should submit curriculumvitae, a statement of research interests, reprints of pub-lished papers, and at least three letters of reference to:Dr. Kent B. Holsinger, Chairman Plant EcologySearch Committee, DEartment ofEcology and Evo-ltionary Biology, U43, 75 North Eagleville Road,Storrs, CT 06268. Applications should be roceived nolater than 7 March 1988. Search #8A270. AffiwatinvActionlEqual Opportunity Employer.

The Austalian National University Applicain arAy pi cations areinvited for anpointmcnt to the position otPOSTDOC-TORAL FAbOW (National Resarch Fellow), Re-scarch School of Biological Sciences. The ResearchSchool ofBiological Sciences seeks a Postdoctoral Fellow(National Research Fellow) to work in collaborationwith Drs. G. D.Farquhar and MLR Badger of thePlant Environmental Biology Group and Dr. T. J.Andrews of the Plant Molecular Biology Group. The

School is undertaking a major expansion of recombinantDNA research in plant molecular biology, focusing onthe molecular analysis of plant performance. A personwith a background in plant molecular genetics and/ormutant selection procedures is required to participate in a

program investigating the genetic basis of plant water-use efficiency using Ar thaliana as a modelsystem. The appointee will investigate natural and in-duced genetic variation in water-use efficiency as reflect-ed by differences in carbon isotope discnination andwill be involved in the physiological and genetic charac-terization ofsuch variance. The position is available for 3years, and can be filled immediately; ideally it should befillcd by mid-year. Applicants sbould bold, or expect togain shortly, a Ph.D. m an appropriate field. Contact Dr.T. J. Andrews (062 49421 before 15 Februy 1988)or, Dr. G. D. Farquhar (062 494492 after 15 Fcbruary1988). Closing date: 29 February 1988. Reference:BS.21.1.1 Salary: Postdoctoral Fe ow Gradc 1 (fixedpoint); $A24,535 to SA28,029 per annum. Applicationsshould be submitted in duplicate to: Thc Registrar, Thestralian National Univerity, GPO Box 4, Canber-

ra ACT 2601, quoting refercnce number and includingcurriculum vitae, list of publications and names of at leastthree referees. The Umversity reserves the right not tomake an appointmcnt or to appoint by invitation at anytime. Furthier information is available from the Registrar.

The Univerity is an Equal Opportunity Employer.

POSTDOCTORAL POSMON AVAILABLE

pporunity for postdoctoral research in biomedicalNMR Medical School NMR facility instrumentationincludes 500-MHz, 360-MHz and 200-MHz Brukerspectrometers, and 40-cm-bore, 2.0-T and 5.0-T in vivospectromeers. Applicant should be skilled in modemNMR techniques and instrumentation. Interest in meta-bolic studies vivo a plus. Please send curriculum vitae,bibliography, and three letters of reference to: Dr. JohnS. Leig, Professor, Biochemistry and Biophysics,University ofPenn vhnia, D501 kichards Building

Philadelphia, PA 19104-6089.

POSTDOCITORAL FELLOW: The Rcgional BoneCcnter at Hclen Hayes Hospital is seeking a postdoctoralfellow to participate in studics on the mode of action,regulation and ontogeny ofthe osteoclast (Project Direc-tor: Dr. David Dempster). Thc successful candidate willjoin a group of investigators engaged in basic and cinicalstudies on osteoporosis as part of a national SpecializedCenter of Research in Osteoporosis funded throughHealth Research, Inc. by the NIH (Principal Investiga-tor: Dr. Robert Lindsay). Studies will be based on an

established in vitro model of isolated ostcoclast activity.Prefcrence will bc given to candidates with a strongbackground in ccll biology and experience in cell and

tissuc culture. Formal training in immunology, hematol-ogy, or biochemistry would also bc advantageous. Start-

pg selaryraiee: S20,000 to $25,000, depending onfiin bencfits. The position is

availabl for 5 years in the flst instancc. Hceln HayesHospital is a Columbia Univcrsity-affiliated, New YorkState Department of Hcalth facility located within casyreach of Ne York City. R esum should bc submittedto: Human Resur Hden Hayes .Hoital Route9W, West Haversw, NY 10993. Health Rsearch,Inc. is an Equa OpportunstylAffimativeAction Employer.

POSTDOCTORAL FELLOWSHIPSHIPPLE CANCER RESEARCH CENTER

Postdoctoral positions are immediately available forPh.D. biochemists, molecular biologists, or experimentalhematologists who wish to concentrate on one of thefollowing:

(i) purification and characterization of hematopoieticgrowth factors relevant to blood cell differentiation andproliferation (Dr. M. J. Murphy).

(ii) interferon receptors and interferon-mediated reg-ulation of cellular gene expression and the underlyingbiochemical mechanisms (Dr. S. L. Gupta).

(iii) isolation and biochemistry of melanoma growthfactors (Dr. M. D. Bregman).Send letter describing research experience/interest, in-

cluding curriculum vitae and names of three referees to:Human Resources Consultant, Hiple Cancer Re-search Center, 4100 South Keteng Boulevard,Dayton, OH 45439-2092.

POSTDOCTORAL POSMON available immedi-ately to study cyclic AMP phosphodiesterasc and Gprotein in Phycomces blaksleanus including their charac-tcrization, modc of action and reconstitution in a heter-ologous system. Experience in a related area of mem-brane biochemistry is desirable. Send resume and names

ofthree references to: Robert J. Cohen, Ph.D., Depart-ment of Biochemist and Molecular Biology,'Uni-versitq of Florida, Collge of Medicne, GaisvilleFL 32610.

POSTDOCTORAL POSITION available immedi-ately for a recent Ph.D. immunologist or molecular

biologist to study at a molecular leve cytokinc produc-tion and disease mechanisms in experimental models ofinflammation. Prior experience in cellular immunologyand/or molecular techniques is desirable. Send curricu-lum vitae and three references to: Roger Kurlander

M.D., Box 3486, Duke UniversityM l Center,Durham, NC 27710. AffirmatiAon/Eqal Opportu-nity Employer.

POSTDOCTORAL POSMONAvailable to study genetic recombination; genetic and

molecular approaches to analyze recombination initia-tion and mismatch repair using prokaryotic systems.

Send curriculum vitae incuding references to: Dr.Brooks Low, Radiobiology Labortores, Yale Uni-versity School of Medicne, 333 Cedar Strect, NewHaven, CT 06510. Yak Univr*y is an Equal Opportu-nitylAffirmativeAton Uniesiy.

POSTDOCTORAL POSMONS available tostudy: (i) The molecular basis of natural killer cellfunction and phenotype (C. Dahl); (ii) The molecularbasis of oncology stimulating factor driven myeloid cellproliferation and diffcrentiation (D. Tweardy); and (iii)The molecular cytogenetics of tumor development andprogression (S. Golin). Background in molecular biolo-gydesired. Additional experience in cellular immunologyor mammnalian cell culture usefil. Send curriculum vitae,summary of research experience, and names of three

references to: Dr. Caro Dah Pitsbuh Cancer Insti-tute, 3343 Forbes Avenue, Pitsb PA 15213. AnAffirmatieAcionlEqual Opounity Empyloyr.

POSTDOCTORAL POSMONA postdoctoral position is available immediately to

study microtubule-associated motility factors and othermicrotubule-associated proteins. Projects involve molec-

ular doning of microtubule-associated protcins frombrain tissue and sea urchin eg; and molecular, biochemi-cal and immunological anaIssis of proteins involved infast axoplasmic transport and mitosis. Send curriculumvitae and three letters of recommcndation to: Dr. Rich-ard Vallee, Prncpal Scicntist, Co-Director of theCancer Cter, c/o Personnel Office, WorcesterFoundation for Experimental Bioloy, 222 MapleAvenue, Shrewsbury, MA 01545.AnEqua Opportuni-ty/Affirmative Action EmployerM/FIH.

POSTDOCTORAL POSMON in molecular biol-ogy available immediatcly to work on cither oftwo NIH-funded projects: eukaryotic ribosomal RNA processing,or growth-related gene expression in polycystic kidneydisease. Applicants should have a recent Ph.D.degree inbiochemistry or molecular biology and experiencc in

recombinant DNA, cDNA cloning, DNA sequencing, or

expression systems. Send curriculum vitae and names ofthree references to: Dr. James P. Calvet, Deprtmentof Bio mistry, Unirsit of Kansas Mcl Cen-

ter, Kansa City, KS 66103. Affinmatie Action/EqualOpportunity Employer.

POSTDOCTORAL POSMONSLipids-Atheroscerosis-Nutrition Training Program

funded by NHLBI. Postdoctoral traineeships are avail-able for research and training in areas of (a) lipoproteinstructure and metabolism, (b) cholesterol and bile acidhomeostatic mechanism, (c) arterial wall and pathogene-sis of atherosclerosis (d) parenteral nutrition and lipidmetabolism, (c) modulation of lymphocyte physiologyand (f) molecular genetics of hyperlipoproteinemia. Fac-ulty includes M. Ashra£ Ph.D., W. P. Balistrei, ALD.,B. N. Campaigne, Ph.D., J. A. Harmony, Ph.D.,D. Y. Hui, Ph.D., J. E. Heubi, M.D., J. E. Fischer,M.D., R L. Jackson, Ph.D., J. M. Vander Bcl-Kahn,M.D., E. A. Stein, M.D., F. Schroeder, Ph.D, D. L.Sprecher, M.D., F. Suchy, M.D, M. T. R Subbiah,Ph.D., andR C. Tsang, M.D. Candidates with a Ph.D.dcgree in biomcdical fields and those with M.D. dcgree,with appropriate reearch experience, are eligible toapply. Applmcantsst be U.S. citizen or hold an immigrant visa.

Send curriculum vitae with three letters of recommen-dation indicating thc special area of research interest to:Dr. M. T. R Subbiah, Program Director, Univerityof Cincinnati Medical Center, 234 Goodman Street,K-Pavilion, M.L #540, Cincinnati, OH 45267.

POSTDOCTORAL POSITIONS IN MOLECU-LAR GENETICS. Positions are available for work ineither of two areas. Projects involve studies on the

structurc, cvolution and impact of SINEs in the humangenome (sec: Annu. Rev. Biohem. 55, 631-661; andTrend in Genetics 2, 76-80) and studies of the cxprcs-sion and mcchanism of cell-cycle regulation ofthe humanthymidinc kinase genc (sec Gene 52, 267-277). Facili-ties, scientific environmcnt and funding for thesc studiesare cxcellent. Salary and starting datc are negotiable.Scnd curriculum vitae and names, addrcsses, and phonenumbers of three references to: Dr. Prescott Deimnger,Department of Biochemisty and Molecular Bioloag,Louisiana State University Medical Ccnter(LSUMC), 1901 Perdido Street, New Orlcans, LA70112. Telephone: 504-5684735. LSUMC is an EquaEmplosent OpporunikyLAffirwPeAaieon Enmpyer.

Function, biochemistry and chemistry of glycoconju-gates has become the focus of our research studies. Atpresent THREE POSTDOCTORAL POSMONSare likely to be available. Two to study physico-immuno-chemistry, expression and function of leukocyte lectin.Experience in protein chemistry/molecular biology pre-

ferred. Studies involve protein sequencing, binding siteanalysis, immunocytochemistry, metabolic and genetic

regulation; opportunity for gene doning and sequencingfor the outstanding applicant. One to investigate chemi-

cal and enzymatic synthesis of oligosaccharides. Cndi-

dates expected to interact with collaborating researchgroups in cell, molecular, and immunobiology. Antici-pated start date 1 April 1988. Reply with curriculumvitae and three references to: Dr. Howard Allen andDr. Xhushi Matta, Roswell Park Memorial Institute,Buffalo, NY 14263.

SCIENCE, VOL. 239

POSITIONS OPENPOSITIONS OPEN

830

PEPTIDE/PROTEIN BIOCHEMISTSThe Maristone Corporation is seeking biochemists inthe following areas of specialization:

Peptide BiochemistPrincipal Investigator/Research ScientistPhD with 2-5 years experience in the pharmaceuticalor agrichemical business, specializing in the structureand function of peptides and the design of syntheticpeptide analogs. Management and planning skillsnecessary.

Computational BiochemistResearch ScientistPhD with postdoctoral experience, specializing inprotein structure analysis by computational methods.Experience with molecular dynamics calculations,energy minimization and water models essential.

Located in the San Francisco Bay Area, The MarlstoneCorporation has developed proprietary technologyfor the rational design of peptides and proteins. Thepositions involve application of that new technologyas well as continued development as part of an inter-disciplinary team.

Please send resume to:Ms. Barbara NovaTheMarlstone Corp.24 Belvedere, Suite HSan Rafael, CA 94901

SUPPORT FOR NEW USERS ATSYNCHROTRON RADIATION ANDNEUTRON BEAM RESEARCH FACILITIESThe NSLS/HFBR Faculty/Student Support Program isdesigned to encourage new users to BNL's NationalSynchrotron Light Source (NSLS) and High Flux BeamReactor (HFBR). The program supports faculty/studentresearch groups by covering expenses incurred duringexploratory visits to BNL and while performing initialexperiments at the NSLS and HFBR. Expenses coveredinclude travel, housing, per diem, and some incidentalcosts.

Both the NSLS and the HFBR are large interdisciplinaryresearch facilities. The NSLS is a dedicated synchrotronradiation user facility with two electron storage rings-avacuum ultraviolet (VUV) ring which operates at anelectron energy of 750 MeV and provides infrared,ultraviolet, and soft X-ray photons, and an X-ray ringwhich operates at 2.5 GeV and provides usable photonfluxes at energies from below lkeV to above 20 keV.Instruments for performing photoelectron,photoionization, fluorescence, and infraredspectroscopy, lithography, microscopy, EXAFS (ExtendedX-ray Absorption Fine Structure), small-angle scattering,diffraction, crystallography, topography, medicalimaging, and other studies are available. Scheduling of

experiments is underway on the VUV ring. Scheduling ofthe X-ray ring is expected to begin during the fall of1988, following completion of a major upgrade programpresently underway.The HFBR comprises a 60 megawatt research reactor,systems for irradiation experiments, and nine beamtubes which supply neutron fluxes to 15 experimentalstations. A cold neutron source is available for inelasticand small-angle neutron scattering experiments.Monochromatic neutron beams in both the thermal andepithermal energy ranges are provided. Instruments areavailable for a wide range of scientific studies Includingneutron diffraction, inelastic scattering, chemical andbiological structure studies, and a number of areas innuclear physics.This program is funded by the U.S. Department of Energy,and is open to U.S. citizens or permanent resident aliensfrom U.S. institutions of higher education.To receive an application form or for further Information,contact: Susan White-DePace, User Administrator, NSLSDepartment, Building 725B, Brookhaven NationalLaboratory, Associated Universities, Inc., Upton, L.l., NewYork 11973. Equal Opportunity Employer m/f.

1)111 BROOKHAVENNATIONAL LABORATORY

[|1I[||ASSOCIATED UNIVERSITIES INC.

DEPARTMENT OF GENETICSA vacancy is available for a Mammalian Population, Cell or MolecularGeneticist at the Assistant Professor level. Candidates with interests inhuman systems will be accorded particular consideration. The tenure-track appointee will be expected to teach an advanced course onhuman genetics, as well as participating in more general offerings atintermediate and/or introductory levels. An appropriately qualifiedappointee may be eligible for substantial research establishmentfunding from the Alberta Heritage Foundation for Medical Research.Candidates for the position should have a Ph.D. and postdoctoralresearch experience. Establishment of an independent research pro-gram will be an integral part of the appointee's duties and excellentresearch potential is considered imperative. The appointment willcommence eariy in the 1988/89 academic year. Salary will be in therange $31,612-$5,340, commensurate with qualifications.Genetics currently has thirteen faculty, housed in a modern researchfacility in the Faculty of Science; research emphasis is molecularbiological. The University of Alberta, Alberta's senior university, has25,000 students. Heavy emphasis on biosciences is found in theFaculties of Science, Medicine and Agriculture and Forestry. Wideopportunities for collaborative research are available. Edmonton is acity of 500,000, a supply centre for agriculture and petroleum indus-tries and Alberta's capital.Optimal starting date is July 1, 1988. Applications will be accepted untilthe position is filled, but would be appreciated before March 31, 1988.Applicants should send a curriculum vitae, reprints of four (or more)recent research publications and the names and addreses of at leastthree referees to:

Dr. David NashChairmanDepartment of GeneticsUniversity of AlbertaEdmonton, Alberta T6G 2E9Canada

The University of Alberta is committed to the principle of equity inemployment. In accordance with Canadian Immigration requirements,priority will be given to Canadian citizens and permanent residents ofCanada.

POSITIONS OPEN

POSTDOCTORAL POSITION in area of electro-physiology (patch camping) as applied to immunophar-macology i a multidiscipllnary setmng. Salary competi-tive. Send curriculum vitae, statc research intcrests, pro-vidc address and tclephone number of threc refrencesto: Dr. RobertM. Donahoe, Laboratory ofPsychoim-Munology, DeEpartsct of itry,Emory Univer-sity School ofMedicne, Georgia Mental Health Insti-tute, 1256 Briardiff Road, Adanta, GA 30306. AnEqu OpportustylAffirnmats Acwn Empkyer.POSTDOCTORAL POSITION: Avaiabie spring

1988 to study the role ofDNA methylation in Ewchericacali. Topics indudc: the specificity of basc mismatchrepair (e.g., NudeicAAd& Rts. 15, 8205); the regulationof gene expression (c.g.,Annu. Rep. Genet. 21, 113) andthe regulation of dm genc cxpression. Background inmicrobiology/molecular biology/genetics an advantage.Send curriculum vitae and names of three refcrences to:Dr. M. G. Marinus, Department of Phmacology,Uniersity ofMasachuss Medical School, 55 LakeAvenue North, Worcester, MA 01655. UAMC is anEqual OpportuniteyffissativeAcain Employer.POSTDOCTORAL POSMONS arc available in

two research areas: (i) the molecular biology of generegulation, high frequency transposition and develop-mental timing in Dicrgteelum, and (ii) the regulation ofcell motility and chemotaxis at the behavioral and molec-ular level in Dicayoeum d4cideum. Send curriculumvitae and names oftwo references to: Dr. DavidR Soil,Departmnct of Biology, University of Iowa, IowaCity, IA52242. ThU niy of Iowa is an EqualOpporunitylAffitatie Action Emetr

POSTDOCTORAL POSMIIONSSYSTEMS ECOLOGY RESEARCH GROUPARCTIC TERRES IAL ECOLOGIST-Partic-

ipate in research project examining ecosystem responseto disturbance near Toolik Lakc, Alaska. Responsibilitiesinclude coordinating ficld research in tussock tundra oncommunity composltion, canopy structures, carbon bal-ance, and production. Expericnce in arctic ecosystcmsand computcr modeling desirable.ECOSYSTEM MODELERS (three)-Two posi-

tions to participate in Toolik Lakc ecosystem modelingproject; cxpcrtise opcn but prefcrcnce given to individ-uals with cxperiencc in arctic ecosystems. Onc position toparticipate in joint project with Dr. F. Ba (HarvardUnmversity) in modeling ofplant competition m rcsponseto elevated carbon dioxidc.

All positions availablc immediately. Send curriculumvitac and names of threc references to: Systems Ecology

arh Group, San Diego State Unimv ity, SanDiego, CA 92182, Attention: Dr. John D. Tenhunen.Tclephonc: 619-229-2862 for terrestrial ecologist;and attention: Dr. James F. Reynolds. Telephone:619-229-2887 for modeing positions. An Equal Op-portntlAffinmative on Employr, Titl IX.

POSIDOCTORAL POSMIIONS are available atthe National Heart, Lung, and Blood Institute, NationalInstitutes of Health, Public Health Service to study thebiochemistry and cell biology of the cytoskceeton andmotility systems of non-muscle cells. Current activitiesinclude the resulation of actin polymerization by actin-binding proteins, and the structure, enzymatic activityand cellular function ofactin-associated and microtubule-associated translocators. These positions have a salaryrange of $20,000 to $37,997 per annum. Salary will becommensurate with experience. These positions are lo-cated on the National Institutes of Health (NIH) campusin Bethesda, Maryland. Please send curriculum vitae andthree letters of recommendation to: Dr. Edward D.Korn, Chief, Laboratory of Ccll Biolgy, NationalHcart, Lung, and Blood Institute, 9000 RockvilkPike, Buildng 3, Room B1-22, Bcthesda, MD20892. An Equal Opportunity Emplyer.POSTDOCTORAL RESEARCH ASSOCIATEPosition availabk to study electrophysiology induding

intracellular recording, single fiber recording and bio-chemical pharmacology of gastointestinal smooth mus-de and ncrves. Ph.D. degrec with prior rcsearch experi-ence desirable. Excellent research facilities. Send curricu-lum vitae and names of threc refcrences to: Raj KYGoyal, MD., Gastroentrology Division, Depart-ment ofMedicne, Bcth Israel Hospit, Boston, MA02215. AffinnativeActionlEqual Opporunity Emlyer.

832

POSITIONS OPEN

U.S. DEPARTMENT OFAGRICULTURE (USDA)

AGRICULTURAL RESEARCH SERVICE(ARS)

POSTDOCTORAL RESEARCH ASSOCIATEPOSITIONS-Positions are available at the NorthernRegional Research Center, Peoria, Illinois, in four areasofresearch: (i) glycoprotein biosynthesis and secretion inmaize endosperm including enzymology of synthesis,structural studies of oligosaccharides, and targeting ofproteins; (ii) regulation of lipid metabolism in soybeansinduding the measuremnts of enzyme activities duringtemperature acdimation and isolation and characteriza-tion of the enzymes; (iii) gcnetic repulation of oligosac-charide biosynthesis in soybeansm mduding enzymolo-gy, protein structure and cloning of key metabolic en-zymes; (iv) characterization ofamylases, glucosidases anddextrinases found in germinating corn including identifi-cation of enzymes capable of invasion and hydrolysis ofintact starch granules. Knowledge and experience inenzyme assays, protein isolation or purification required.Appointments will be at GS-11 ($27,716) for 1 year andcan be extended. Please send curriculum vitae and namesof three references to: Hekn Sweeny, Personnel De-partment, USDA-ARS-Northern Regional ResearchCenter, 1815 North University Street, Peoria, IL61604. Applications in response to this announcementmust be marked 8N005. Additional information may beobtained by calling: (i) J. A. Miernk, (ii) Tom M.Cheesough, (iii) Tsung M. Kuo, (iv) Clarce A.Knutson at 309-685-4011.ARS isa#Equal Op uni-ty Employfr.

POSTDOCTORAL RESEARCH ASSOCIATE-Ph.D. in immunology/medical microbiology with aminimum of 2 years of cxperience in hand micerabbits, viruses; tissue culture; isolation and culture oflymphoid cells; production purification, and analysis ofmonoclonal antibodics and lymphokines; HPLC andcolumn chromatography. Must be proficicnt in the de-sign of ecperimcntal protocols, and in writing of reportsand papers. The supervision of one to three technicians,graduate students, and other research associates in relatedresearch projects is required. Also, the supervision andupkeep of equipment for a group of eight to twelveinvestigators IS required. Full-time 40 hours per week, 9a.m. to 5 p.m., Monday to Friday. Salay Ls f22,500 peryear. Send rsumd to: Case #8217 Division of Em-ployment Security, Charles F. Hurley, EmploymentSecurity Building, Government Center, Boston, MA02114.

BOSTON UNIVERSITYCENTER FOR MOLECULAR BIOPHYSICSPOSITDOCTORAL RESEARCH FELLOWSSeveral positions are available for postdoctoral re-

searchers to participate in studies of macromolecularassemblies using x-ray and neutron diffraction and elec-tron microscopy. The focus of these studies is thedevelopment ofnew methods for the study ofmacromo-lecular struure. Biological systems being studied in-dude filamentous bacteriophages, membrane gap junc-tions and amyloid fibers. Background in x-ray crystallog-raphy, electron microscopy, image analysis or membranebiochemistrypreferred. Please send curriculum vitae andthe names ofthree references to: Dr. Lee MakowskCenter for Moleculr Biophysics, Department ofPhysics, Boston University, 590 Commonwealth Av-cnuc, Boston, MA 02215.

Boston Unn y is an Equal Opptuty Employer.

POSTDOCTORAL RESEARCH SCIENTIST-Columbia University, the Ncw York Orthopacdic Hos-pita Research Laboratory. A 3-year postdoctoral posi-tion is available within tec biochemistry section of anactive multidisciplinary rescarch team in a newlyequipped laboratory. Arcas of interest indudc the com-position, turnover and degradation of articular cartlageand intcrvertebral disc. Candidates should be knowledge-able in protein/carbohydrate biochemistry, immuno-chemistry, tissue culture and/or molecular biology. Com-petitivc salary range of $26,000 to $32,000 per annum.Interested candidates should send their curriculum vitaeto: A. Rateliffe, Ph.D., Orthopaedk Resarch Labora-tory, Columbia-Presbyterian Medical Centa, 630West 168th Street, Ncw York, NY 10032. CoumbiaUniversny is an Equal Opportunity Employer.

POSITIONS OPEN

POSTDOCTORAI/RESEARCH ASSOCIATE-position available immediately to conduct research in thearea of genetic recombination and microbial differentia-tion, analyzing cloned genes required for genctic trans-formation in Strepoocu pneumosae. Candidate musthave Ph.D. and a background in microbial genetics ormolecular biology. Salary commensurate with experi-ence. Send application letter, curriculum vitae, andnames of three references to: Dr. Donald A. Morison,Professor, Laboratory for Cell, Molecular, and Devel-opmental Bioky, lUmversit of Iinois t Chio,(m/c 067), P.O. BOX 43f hcp L660.Telephone: 312-996-6839. An EqsA3pp /Af-fitmativcAction Employr.PROFESSORSHIP IN BIOLOGICAL NMR.

AND MACROMOLECULAR STRUCTURE atHarvard Medical School. The Department of BiologicalChemiistry and Molecular Pharmacology ised inbuilding a program in structural biology an mvitesapplications for a professorship in biological NMRApplicants should have an outstanding record ofachieve-ment in NMR in structural proteins and/or mechanisticstudies of proteins, glycoproteins, or nudeic acids. Wcseek individuals with strong interdisciplinary interests tointeract with current biochemistry and pharmacologyfaculty.

Interested candidates should send curriculum vitae to:Professor Christopher Walsh, Department ofBiolog-ical Chenistry and Molr Pacogy, Har-yard Medical School, 25 Shattuck Street, Boston, MA02115. Harvard Mdal Sdool is an Affirmative AcionEqual Opportunity Employer.RESEARCH ASSOCIATE: Will perform research

and analysis of the physical properties of biologicalmacromolecules using NMR techniques. Will study thestructure and dynamics of peptides and DNA and theirinteraction using NMR spectrometer and HPLC. Willperform molecular modehng using computers and devel-op appropriate techniques for studies of structures anddynamics of DNA and peptides by modiing NMRtechniques through development of computer software,new pulse sequence techniques, and hardware develop-ment. Requires Ph.D. degree in chemistry. Education toinclude 2 years of research on peptide structures andDNA dynamics using NMR spectrscopy, indudingmaintenance and software development as well as com-puter molecular modeling. Hours: 8:30 a.m. to 5:00p.m. Forty hours per week at $20,700.00 per year salary.This job is a university position. Please send r6sumi to:TIinois Deprtment of Employment Security, 401South State Stroet South, Chicago, IL 60605.Attention: Marie Ninneman, Reference #7594-N, AnEmployer paid ad.

RESEARCH ASSOCIATEConduct cardiovascular research directed toward the

study of ionic and/or non-ionic drugs such as renografin,iopamidol, iohexol, iovesol, and angiovist and their effecton the cardiovascular system. Applying knowledge ofsurgical techniques and working with test animals, candi-date will inject dogs with aforerentioned drugs throughcardiac catheterization to study effects on cardiovascularsystem and their relationship to hemodynamic changes(cardiac functions), cardiac rhythm disturbances (ECGevaluations), ventricular functions, aortic blood pressureand related activity to prevent serious arrhythnia andsudden heart death during coronary angqzography. Study,evaluation and analyses of angiograms. Th-is is a universi-ty position. Candidate must have medical degree orPh.D)., and 4 years of direct experience. Salary offered$22,010.00 per year, 40 hours per week, 8:30 a.m. to4:30 p.m., Monday to Friday. Send resume to: IllinoisDepartment of Employment Security, 401 SouthState Street-3 South, Chicago, IL 60605. AttentionRobert S. Fehon, Ref. #V-L 7448-F. An employerpaid ad.

RESEARCH ASSOCIATEResearch associate with Ph.D. in pesticide chemistry

to carry out studies on the phannacokinetics and metabo-lism of organophosphorus compounds and the naturallyoccurring malc contraceptive gossypol using GLC,HPLC, and TLC, as well as scintillation counting. Fortyhours per week. Salary: $20,000. If not a U.S. citizen,please indicate visa status. Apply: Employment SecurityCommissi 516 North Mangum Stroet, Durhm,NC 27701 or your local job service office. Job ordernumber NC 7101097. DOT codes 090.227-010. Affir-matnvcAcaion/Equal Opportunity Employer.

SCIENCE, VOL. 239

POSITIONS OPEN

RESARCH ASSOCIATE po avae forqlifi candidate to wdok in a multidiscplinary unitwithin aCenter ofCell andMolerlarBiobgyintheaof unolg with a pnc_ inm anti-bodies, -LSA and asynmhods. For fiutherinformation call: 312-702-1775 or write: Dr. A. hLScau, L Study Unit, 841 South Mar-lad A e, Box 231, Chiago, IL 60637. seUniverstyfCloiCAro sras Equa Opp0misy Emplwr.

RESEARCH ASSOCIATE-BIOCHIEISETYAresearch asatsIrin is available incinMx-ray and

neutron dn .Ainalysof.hydmrenhbondingr networks wilFxmn=szdl -rnsion hese studies into p a nudcic ads isanticipated. Exprinc in crystlorpybyiocheistrydesirable. Send risuzni to:

Dr. Bran E. HigertyOak Ridge Natonal LIboratory

Hudthan(USsety Resarch DhisonBuildHn 9207, MS 002Oak Ridg, TN 37831

An Equa OppeunityLdfImmasimcAaim Explyer

RESEARCH FACULTY POSMONI epDqmen of Obstetrics and Gyncolog, Uni-

versty of Forida Colkge of Medicne, under t direc-tionofByronJ. M.D, Profso and Chair-man, is seekng applian for a temur-rack fiauly

position(Ph.D.) st gAust 1988 for candidatesdemonstrating exceptionalresearch abiities with astog bakron and exeiec in ulrstrcuastudies, wound heali~ plantation, eletrn micralpy, and moecur . The individual should beprepard to establish an, ah p mand assume teachinglesponsibilites. Po r expe-rince in arlaed fied is ruir Salay ad rnkdepnd upon qualicio For fiull i ,applicas should submit Acrrium vitae and a bifstatemnTt of research interest by 1 March 1988 to:William C. Buhi, Ph.D, Depat of O eriand G o,U of Fida Cole ofMe.dicn, Gain,esville,FL3 10.

An Equa Emplyment OAMAaionE r

SCIENTISrIhe Universities Spae Research Association (USRA)

has a nced for a scecntto p dina, orixe,documnat, and miabute rtdto various microgvit sience expeimn ininUSRA, NASA and univesity s Work sinchlude coordinon ofmu er nds, fic evalu-ation of re m s as rrds im I, en-handng co un among proecr scienist andbtweensc and implemention persnL Candi-dates should hold a mimum of a masters degree inphysics, matrials scienoe, materials me-chanial engineerng, or a related field and appeboth physical and biom cal p r d tomicrgravity science. Candidate wih a Ph.D. are en-couraged to applr. Good vebal and written skills as wellas a williness to travd are also nede Adthe must have a gofoelips bwen various NASAco s(elhrMasl pace Fligt Center), USIA, dhs-

sponsored university scientists as eds the evolion ofmiCrogravity scmcne experit m t l hy-pothcsis irough tos l flight hardwe. Work wllkbconducood at the Marshal Space Fit Center. Salrycommensurate with (minimum $35,000 peryear) with full medical and bmen fits. Sendrdsuma to: USRA, Dr. Jame ML Van Altne, 139-AMcMurtrie Drive, H e, AL 35806. USRA is anEqua OpperrukylAjlmaiwAais Emplyer.

INSTITUTE FOR MOLECULARBIOLOGY (IMB), TAIPEI

SCIENTISTS with Ph.D.s are invited to ayp forpositions in plant moleulr biology, pteeeintaInd macroeula x-r aycrytllograpy. rdescrptn Of research pla, d two ktrs of room-mendation befioe 15M 1988 to: Dr. Ray Wu,Section ofBichemistry andbMobulr Biology, Cor-nell Uniersy, Ithaca, NY 14853.

I2 FEBRUARY 1988I

POSITIONS OPEN

SENIOR RESEARCH SCIENTISTPDS Research Laboratories is seeking a person with a

Ph.D. degree and experience in virology, molecularbiology, and/or protein chemistry. Applicants must haveI to 3 years ofpostdoctoral training with published workin his or her research area. This position reauires a goodunderstanding of human retrovirology an offers highvisibility and interaction with members of prominentscientific institutions including National Institutes ofHealth, U.S. Department of the Army and Food andDrug Administration through collaborations, publica-tions and presentations. Salary commensurate with expe-rience, and comprehensive benefits.

Applicants are invited to send a complete curriculumvitae to:

PDS Research LaboratoriesAttention: Dana Lee

13 Taft CourtRockvie, MD 20850

Telephone: 301-294-2297

STAFF SCIENTISTMaeronk Inc., the international leader in implanable

pacanakers, is seeking an individual with gradate orpostgraduate work in bi n ing or physiology, andseveral years of expeicne in cardiovascular research. Thisperson will conduct studies and work with dinical consul-tants in evaluating the feasibility of novel pacing and othercardiovascular diagnostic and therapeutic concept. Experi-ence in acute and chronic ani studies and use ofappropriate inst nts is essential. A Ph.D. in this field ispreferred. Submit rmcurriculum vitae to: Vera Brew-crs, Medtronic Inc, 7000 Cental Avenuc NE, Minne-apols MN 55432. Equl Oppotunity Employer.

VISION SCIENCE. Tenured or tenure-track posi-tion, rank and salary commensurate with qualifications.Vigorous research program in visualpsychophysics, will-ingness to particpate in teaching vision sacnce to op-tometry students. Scnd lettcr of application, curriculumvitae, names of three references to: Dr. Jerry L. Chris-tensen, School of Optometry, Univesity of Missou-ri-St. Louis, 8001 Natu Bridge Road, St. Louis,MO 63121. Application deadline: 24 March 1988. AnEqual Opporunity Inesumn.

ZOOLOGIST/ECOLOGIST, tenure-track, startingfall, 1988. Ph.D. and strong intercst in underrduateteaching (induding gencral biology) required. ABDsconsidered. Send resume, and threcletters of recommen-

dation to: Director of Personnel Services, SouthwestState Univeity, Marshall, MN 56258. Screening willbegin 1 March 1988.

Southwest State University is an Equal Opportunity Edu-caor and Employr.

COURSE

MARICULTURE: CULTURE OF MARINE IN-VERTEBRATES FOR RESEARCH PURPOSES.Designed to teach the basics of mariculture to advancedstudents, this course is scheduled for 22-28 May 1988.Tuition: $850 (indudes room and board). Applicationdeadline is 1 April 1988. For fiuther information, con-tact: Thc Office of Sponsored Programs, MarincBiological Laboratory, Woods Hole, MA 02543.Tclcphone: 617-548-3705, extension 216.

INTERNSHIP

ILLINOIS LEGISIATIVE SCIENCE INTERN.Sanganon State Univcrsity invites applications fromgraduates of science or engineering programs (baccalau-reate, mastcr's, doctoratc) for two 10½2-month scienceintemships beginning 1 October 1988 as part of theIllinois Lcgislative Staff Intcrnship Program. Thc scicnceinterns will be assigned to the Springfield and Chicagooffices of the Illinois Legislative Rcscarch Unit whichprovide legislators with information and research aboutpolicy issucs. Thc scicncc intcrns will partcipate in anacadcmic seminar with other legislativc intcrns. Sendcurriculum vitae by 15 March 1988 to: Dr. KentRedfield, Coordinator, Illinois Legslativ Staff In-ternship Program, an State Unvty

Sprngfid, IL 62794-9243.

834

TRAINING PROGRAM

FELLOWSHIPS

FELLOWSHIP IN CELL-MICROCIRCULA-TORY PHYSIOLOGY. A position is available 1 July1988 for the study of cell-cell communication in mi-crovessels. Applicants should have an advanced degree inphysiology, pharmacology, or cell biology. Training in

electron microscopy, electrophysiology, or cell-cell com-munication is desirabl. Applicants should send letters ofrecommendation and resum£s to: Dr. Brian R. Duling,Department of Physiology, School of Medicine, Box449, Charlottille, VA 22908. We are an EqualOppounity Enmloyer.

INTERNATIONAL CANCER RESEARCHFELLOWSHIP

The Hayashibara Mutual Aid Fund, a non- rofit-making organization within the Hayashibara groupannounces a fellowship program. Two awards will bemadc annually. Fellowship will be taken up at the newlyopened Fujisaki Cell Center which is devoted to basicand applied related to problems in humancancer. The fellowship is normally madc for 1 year and isrenewablc for up to 5 years. The fellowship will beexpected to commen c within 6 months ofthe announcc-ment of the awards. The awards arc for high qualityresearch work in onc of the threc categorics describedbelow.

1) Fundamental Leukia-Lymphoma Rcsearch,2) Cytokine-Lymphokine Rcscarch,3) Hematopoietic Ccll Culturcs.Qualified person who has a Ph.D., an M.D. or equiva-

lent qualifications will be awarded on merit to suitablyqualified research proposal and experiences. Additionalinformation and application forms will be obtained fromJun Minowada, Mi)., Dirctor, Fujiski Cell Center,675-1, Fujisaki, Okayama 702, Japan.

MARINE BIOLOGICAL LABORATORYMARINE ECOLOGY FELLOWSHIPS

Outstanding applicants to the 1988 summer MarineEcology Course (see Scince 8 January 1988 issuc) by 1March 1988, are eligible for two, full fellowships (tu-ition, plus room and board). Information available from:Marine Biological Laboratory, Woods Hole, MA02543. Telephone: 617-548-3705, extension 216.

THE ARNOLD ARBORETUM OFHARVARD UNIVERSITY

THE KATHARINE H. PUTNAMFELLOWSHIPS IN TREE SCIENCE

Applications are invited from established scholars seek-ing sabbatical opportunities or from young scientists,who wish to pursuc research which would substantiallybenefit from access to the living woody plant collectionsof the Arnold Arboretum, and their supporting herbariaand libraries. Fellowships are tenable for up to 1 year.Fields of research can indude theorctical and appliedbotany, horticulture, forestry, landscape architecture andrelevant social scicnces. Appointees must be willing totcach a course in the University. The fcllowship willprovide a salary plus fringe bencfits according to HarvardUniversity norms. Travel costs to Boston will be rcim-bursed.

Applications for 1988 to 1989 should be forwardedtO: Pctr S. Ashton, The Arnold Arboretum of Har-vard University, 22 Divinity Avenue, Cambridge,MA02138, by 29 February 1988.

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIPMEDICAL UNIVERSITY OF

SOUTH CAROLINAOne-year intensive training program in alcohol re-

search. Funded faculty research programs include alcoholteratology, behavioral pharmacology, neurochemistry,and membrane biophysics. Fellows available begin-ningrJuly 1988. Applicants must beU.S. citizens withPh.D. or M.D. Send curriculum vitae and three refer-ences to: Dr. Carrie Randall, Alcohol FellowshipDirector, Research Servicc, 109 Bee Street, Charles-ton, SC 29403. Application deadline is 15 March 1988.Equal Opporuniiy Enmloyer.POSTDOCTORAL FELLOWSHIP: In biological

chemistry and molecular biology, to study the purifica-tion, antiserum production, and molecular cloning froma cDNA library of transforming growth factors inducedby x-irradiation of plateau-phase mammalian bone mar-row stromal cell lines. Ph.D. in molecular biology orbiochemistry. Please send curriculum vitae and threeletters of recommendation to: Joel S. Greenberger,M.D., Department ofRadiation Oncology, Universi-ty ofMassachusetts Medical Centcr, 55 ]Ck AvenueNorth, Worcestcr, MA 01655. UMMC is an EqualOpportunitylAffirmativeAtion Employer.

The California Institute of Technology, Division ofEngineering and Applied Scicnce, invites applications forPOSTDOCTORAL FELLOWSHIPS, including:

THE DR CHAIM WEIZMANNPOSTDOCTORATE FELLOWSHIP

FOR SCIENTIFIC ANDENGINEERING RESEARCH

(Restricted to U.S. citizens)THE MYRON A. BANTRELL

POSTDOCTORATE FELLOWSHIPFOR SCIENTIFIC AND

ENGINEERING RESEARCH(Rcstricted to U.S. and Israeli citizens)

Caltech's Division ofEngineering and Applied Sciencewill award a limited number of postdoctoral fellowshipsfor research in Engincering and Applied Science. Thefellowship will have a onc- to two-year duration, begin-ning in the fall or winter of 1988. The program isintended for those who have just completed their Ph.D.

Inquiries should be addressed to: Professor Paul C.Jennmngs, Chairman, Division of Egineering andApplied Science, California Institute of Technology,Pasadena, CA 91125. The deadline for completedapplications is 30 May 1988.

The Imutea s An Equal OppwtunityAffinnaiw AaonEnq*or a weksne andwnd o.*.

POSIDOCTORAL RESEARCH FELLOW-SHIPS-VISION LMMUNOLOGY. The Vision-Im-munology Center of the University of ConnecticutHealth Center currently has available postdoctoral re-search fellowships for qualified individuals (Ph.D., M.D.or equivalents) m the areas of ocular inflammation andrepair, transplantation, autoimmunity, cellular and mo-lecular immunology. All positions are supported by NEITraining Grant and salaies and fringe benefits are con-sistent with NIH Guidelines. For fiuther information,send requests and curriculum vitae to: Dr. JamesO'Rourke, Vision-Immunolo Center, University ofConnecticut Health Center, amingto, CT 06032.An AffirmativeActionlEqual Op ni Employer.

PREDOCTORAL FELLOWSHIPSIN BIOMEDICAL ANDPHYSICAL SCIENCES

Biochemisty * Biology * Biomathematics * Biomedi-cal Engineering * Biophysical Sciences * Biostatistics eChemistry * Computer Science 0 Cell Biology andAnatomy * Environmental Health * Epidemiology SGenetics * Immunology 0 Materials Engineering SM.D.-Ph.D. * Medical Genetics * Medical Psychology SMicrobiology 0 Molecular Cell Biology * Neuroscience* Nutrition Sciences 0 Pathology * Pharmacology.Physics * Physiological Optics * Physiology * PublicHealth * Virology

Well-funded faculty with diverse intrests. Good post-graduation placement record. Above-average stipendsinclude payment oftuition. Ready access to CRAY-XMPsupercomputer. Contact: The Graduate School (A),University ofAlabama at Birmingham, BirminghAL 35294; Tdelphone: 205-934-8246. Equal Opportu-niav/AffitwafiveAcaion Instution.

SCIENCE, VOL. 239

NEUROSCIENCE TRAININGPROGRAM EMORY UNIVERSITYApplications are invited for graduate fellow-

ships in neuronal cell biology and biophysics,neural systems and psychobiology. The programcombines intensive interdepartmental training inneuroscience with the opportunity to specializein one of the traditional disciplines. Interestedcandidates with a strong background in biologi-cal and physical science may obtain further infor-mation from: Director, Neuroscience Pro-gram, Department ofAnatomy and Cell Biol-ogy, Emory University, Atlanta, GA 30322.Telephone: 404-7274315.

When you

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