PersonnelPlacement

POSITIONS WANTED

Biochemist, Ph.D. 1980, experience in lipid analysis,phosphoinositide metabolism, ligand-binding assays,keenZy interested in effects of disease and diet on signaltransduction mechanisms, seeks research position, prefer-

ably in the Philadelphia-New Jersey-New York Cityregion. Available fall 1987. Box 48, SCIENCE

4/17, 24; 5/1

Biochemist, Ph.D. Innovative researcher interested indrug and vaccine discovery and development for infec-tious diseases. Research and teaching expenrence in in-

dustry and university. Extensive bibliography. Seeksresearch/teaching position in industry/university. Box 49,SCIENCE. 4/17, 24

Biochemist, Ph.D. Research experience: cell membraneproteins, antibody preparation, immunoassay develop-ment, Western blotting, cell culture, mutant isolation,metabolism, oxidation-reduction and ATPase enzymes.Publications. Johns Hopkins traming. Good communi-cation, creative, and analytical skills. Seeks leadershipposition cutting-edge environment. New Jersey area,other considered. Box 50, SCIENCE X

Bioengineer/Physiologist, Ph.D. Publications, patents,30 years academic, industrial, government biomedicalR&D experience, including basic and applied research,clinical investigation, teaching, product development,administration, patent litigation, and contract manage-ment. Desire free-lance professional assignments, long!short term. P.O. Box 9106, La Jolla, CA 92038. Tele-phone: 619-456-2565. 4/17, 24

344

Polymer Professor. Highest academic qualifications andindustrial experience seeks temporary post in Americas.Patents, books, and 150 research papers on polymers.U.K. citizen. Replies to: 2 Moorfield, Newcastle onTyne, NE2 3NL ENGLAND. X

Renal physiologist/toxicologist. Ph.D. 1977. Eighteenyears of experience in research in membrane physiopa-thology and cell metabolism. Three years ofexperience in

teachin biological sciences. Broad biology background.Seeks challenging research/teaching/consulting positionin university/hospital/industry. Box 45, SCIENCE. X

POSITIONS OPEN

ANATOMYUNIVERSITY OF SASKATCHEWANDEPARTMENT OF ANATOMY

The Department of Anatomy, University of Sas-katchcwan, College of Medicine, invites applicationsfor tenure-track position at the ASSISTANT PROFES-SOR level. Applicants should have experience in teach-ing developmental biology to medic an science stu-

dents as well a teratology and possibly neuroanatomyand/or gross anatomy. Background in molecular biologyis desirable. Applicants should have proven researchbackground an a strong research program. Application,including curriculum vitae, names of three referees, andan outline of proposed research should be submitted to:Dr. G. D. Burkholder, Department of Anatomy,College of Medicine, University of Saskatchewan,Saskatoon, Saskatchewan, Canada S7N OWO. In ac-cordance with Canadian immigration rcquirements, thisadvertisement is directed to Canadian citizens and perma-nent residents.

ANIMAL/CELLULAR PHYSIOLOGIST

Seek a tenure-track assistant or associate professor todevelop a viorous research program in animal physiolo-gy at the celular level. Appropriate areas would be, butare not lited to, mechanisms of hormone action,receptor physiology or membrane physiology, and bio-chemistry. Teaching responsibility will be in a graduate-level course in systenic physiology of domestic animals.Successful candidates will have a Ph.D. in cellular physi-ology and biochemistry with a strong background insystemic physiology and a desire to develop superiorteaching and research programs. Postdoctoral experiencepreferred, as is teaching experience, in systemic physiolo-

gy. Expected to develop extramural funding for researchto supplement appropnated support.Submit a detailed resum of education (including

transcripts), experience, qualifications, and publcationsand a list of three references by 15 May 1987 to: Dr.Elton D. Aberle, Head, Animal Science Department,University of Nebraska-Lincoln, Lincoln, NE68583-0908. AffirmativeActionlEqual Opportunity Em-ployer.

ASSISTANTOR ASSOCIATE PROFESSOR OFPLANT PATHOLOGY AND MICROBIOLOGY.Tcxas A&M University. A permanent, 100% researchposition with an opportunity to teach and supervisegraduate students is available 1 September 1987. Qualifi-cations include a Ph.D. in plant pathology or related fieldand demonstrated ability to do independent and cooper-ative research. The incumbent will participate in aninterdisciplinary small grains program directed towardimplementing disease management strategies based onplant and pathogen populaton dynamics. Research ac-tivities w include deployment of disease resistancegermplasm; determination and flow of virulence factors;influence of resistance, pesticides, and environment onpathogen populations; and quantitative epidemiology.Applicants please send letter of application, detailedresume, transcripts, selected reprints, statement of pro-fessional goals, and names of three references by 15 June1987 to:

Dr. J. Artic Brownig, HeadDepartment of Plant Pathology and Microbiology

Texas A&M UniversityCollegc Station, TX 77843-2132

The Tecas AYMf University System is an AffirmatveActionlEqual Oppotunity Employer.

ASSISTANT DIRECTOR OF ANIMAL CARE,BROWN UNIVERSITY. The Division ofBiology andMedicine is seeking applications for the position ofAssistant Director of Animal Care to begin as early asAugust 1987. The individual will assist the Director ofAnimal Care to provide veterinary management of ani-mal care facilities in the University and in hospitalsaffiliated with the Brown Medical Program. In additionhe/she will review animal research grant proposals, adviseinvestigators and the Animal Research Committees, pro-vide surgical support to investigators as needed, andsupervise animal care personnel. Candidates must holdthe D.V.M., V.M.D., or equivalent degree from anaccredited school of veterinary medicine and have com-pleted a residency in surgery or laboratory animal medi-cine or have equivalent experience. The position offerspotential for collaborative or individual research and forteaching activities. Applicants should submit curriculumvitae and have three fetters of reference sent to: Dr. JeanMarshall, Box G, Brown University, Providence, RI02912 by 15 June 1987. Brown University is an EqualOpportunitylAffirmative Action Employcr.

ASSISTANT MEDICALRESEARCH PROFESSOR

The Division of Genetics and Metabolism is seeking abiomedical mass spectroscopist to enhance an active andexpanding research program. The initial appointmentwill be a nontenured, Assistant Medical Research Profes-sorship. Responsibilities will indude operation andmaintenance of a VG 70-S mass spectrometer, participa-tion in collaborative clinical and biochemical research,maintaining and expanding a service to other depart-ments, and development of an independent researchprogram. This is an excellent opportunity for the success-ful candidate, who is expected to hold a Ph.D. degree inchemistry or biochemistry and to have had at least yearsof previous traiing and experience in mass spectrome-try, preferably with high-resolution instrumentation. In-terested candidates should apply in writing to: Dr. D.S.Millington, Box 3028, Duke University Medical Cen-ter, Durham, NC 27710 before 8 May 1987. Affirma-tiveAction/Equal Opportunity Employer.

ASSISTANT OR ASSOCIATE PROFESSOR ofpharmacology and toxicology. Tenure-track position.Applicants should possess an M.D. or a Ph.D. in phar-macology, toxicology, or a related scientific discipline.Candidates should have 3 years or more of postdoctoralexperience, evidence of excellence in research, interest inteaching medical and graduate students, and ability toestablish and support an independent program of re-search. An active research interest that brings molecularbiological approaches to pharmacology is sought. Sub-mit current curriculum vitae, names of three references,and a statement of research plans to: C. W. Cooper,PhD., Chai;nman, Department of Pharmacology andToxicology, University ofTexas Medical Branch, Gal-veston, TX 77550. Equal Opportunity EmployerlAffirma-tive Action.

ASSISTANT PROFESSORCELL OR MOLECULAR BIOLOGY

The Departmcnt of Biology at Syracuse Universityis seeking a person with a Ph.D. and postdoctoralexperience in connective tissue studies for a full-timetenure-track position. This individual will contribute to amajor program of growth and development within theDepartment, induding construction of new researchfacilities, increased commitment to the graduate pro-gram, and the addition of several faculty members in eachof the next 5 years.The successful candidate will be expected to develop an

active, externally funded research program and to partici-pate in the teaching activities of the Department. Prefer-

ence will be given to individuals with background andinterests appropriate for participation in a current pro-gram project dealing with the effects of hormones andgrowth factors on connective tissues as a function of age.

Candidates should send a current curriculum vitae, astatement of research plans, and the names of threeindividuals from whom letters of reference may beobtained to: Dr. Judith Ann Foster, Biology Depart-ment, 130 College Place, Syracuse, NY 13244-1220.Applications will be accepted until 15 June 1987.

Syracuse University is an Equal OpportunitylAffirmativeAction Employcr.

SCIENCE, VOL. 236

POSITIONS WANTED

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

UNE CLASSIFIED ADVERTISING DEADLINES:Thursday, 2 weeks prior to issue date (mailed on issuedate).

POSITIONS WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSITIONS OPEW, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$35.00 per line; $350 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading and/or extra spaces, and allpartial lines are counted as full lines. To calculate cost,multiply total lines x $35.00 = total cost of ad.

Send copy for all Positions Wanted ads and UneCliMed ads less than 1/6 page in size (39 lines) to:

SCIENCE Claiffied AdvertIsIng1333 H Street, NW, Room 940

Washington, DC 20005Telephone: 202-326-6555

Send copy for Fractional Display ads, 1/6 page andlarger, and all Marketplace ads to:

Scherago Asociates, Inc.1515 Broadway

New York, NY 10036Telephone: 212-730-1050

Blind ad replies should be addressed as follows:

Box (give number)SCIENCE

1333 H Street, NWWashington, DC 20005

POSITIONS OPEN

POSITIONS OPEN

The Department ofVeterinary Biosciences, Collof Veterinary Medicine, University of Illinois, TSr-bana-Champaign is seeking applications for two regulartenure-track positions at the ASSISTANT OR ASSO-CIATE PROFESSOR level in the area of veterinarymacro- or microanatomy. Individuals will teach eithermacro- or microscopic anatomy in the veterinary medicalcurriculum and will bc expected to develop a researchprogram and participate in graduate instruction. Currentresearch interests in the group are in endocrine/reproduc-tive and hard tissue studies.

Candidates should possess the Ph.D. degree or equiva-lent with preference to those who also hold the D.V.M.or equivalent. The applicant must use English fluently.Salary commensurate with qualifications. To ensure fullconsideration, applications should be received by 30 May1987. Starting date on or after 1 July 1987.Send curriculum vitae and three letters of reference to:

Dr. W. C. Wagner, Head, Veterinary Biosciences,University of Illinois, 2001 South Lincoln, Urbana,IL 61801; telephone: 217-333-2506.

The University ofIllinois is an Affirmative AcionlEqualOpportunity Employer.

ASSISTANT PROFESSOR (tenure track). The De-partmentofOphthalmology and the Department ofMicrobiology, 7Biochemistry and Molecular Biologyat the Univcrsity of Pittsburgh School ofMedicine areseeking an individual with an active research program inthe cellular and molecular biology of chlamydial infec-tions. Highly qualified individuals pursuing related areasof research mterest are also encouraged to apply. Thesuccessful candidate will hold a joint appointment in thetwo departments, will be expected to establish an inde-pendent research program and develop an interest in theocular complications of chiamydial infections. Postdoc-toral experience is required, and preference will be givento candidates with funded or pending research support.A competitive salary, start-up funds and research space inThe Eye and Ear Institute of Pittsburgh are available.Please submit your curriculum vitae and research synop-sis (two pages) by 1 July 1987 to: Dr. David K. Wilcox,Department of Ophthalmology, University of Pitts-burgh School ofMedie, Room 1015, Tbe Eye andEar Institute, 203 Lothrop Street, Pittsburgh, PA15213. The Univerity ofPittsfurgh is an Equal Opportun-ityAffirmative Action Employcr.

ASSISTANT PROFESSOR (tenure track). The De-partment of Ophthalmology and the Department ofMicrobiology, Biochemistry and Molecular Biologyat the Universitq ofPittsburgh School ofMedicine areseeking an individual with an active research program inthe molecular biology of the extraccllular matrix. Thesuccessful candidate will hold a joint appointment in thetwo departments, will be expected to establish an inde-pcndent research program and develop an interest inocular diseases associated with scar formation. Highlyqualified individuals pursuing related areas of r chare also encouraged to apply. Postdoctoral experience isrequired, and preference will be given to candidates withfunded or pending rcscarch support. A competitivesalary, start-up fund, and research space in The Eye andEar Institute of Pittsburgh are avaiable. Please submitcurriculum vitae and synopsis (two pages) by I July 1987to: Dr. David K. Wilcox, Department ofOphthalmol-ogy, University of Pittsburgh School of Medicine,Room 1015, The Eye and Ear Institute, 203 LothropStreet, Pittsburgh, PA 15213. The Univety of Pitts-burgh isanEqualOpportynilyAffirmativeActionEmployer.

ASSISTANT PROFESSOR IN MEDICINE-Univcrsity of California, San Francisco. This is atenure-track position for a faculty member in the metab-olism division of the Department of Medicine. Theappointee wlll beexpected to augment the strength ofthe division in clinical diabetes and to develop a researchprogram on the molecular biology of insulin secretion/action and its application to human diabetes mellitus.The appointee must have a background of training andaccomplishments in molecular biology and be Board-eligible/certified in endocrinology/metabolism. Send cur-riculum vitae to: Richard J. Havel, M.D., ScarchCommittee Chairperson, Department of Medicne,Box 0130, University of California, San Francisco(UCSF), San Francisco, CA 94143. UCSF is an EqualOpportunitylAffirmative Action Employer. Women and mi-norities are encouraged to apply.

ASSISTANT PROFESSOR OF BIOTECHNOL-OGY: Biology Department, University of Coloradoat Colorado Springs, invites applications for 1-yearappointment with annual renewal considered. Duties: (i)Conduct research on molecular biology of industrialyeast (75%). (ii) Develop two-semester biotechnologylab for undergraduate and graduate students. Ph.D. andrecombinant DNA experience required. Postdoctoralexperience prcferred. Send curriculum vitae, reprints,and three reference letters to: Dr. James R. Mattoon,Biology Department, University of Colorado, Colo-rado Springs, CO 80933-7150.An Equal OpportunityEmployer.

ASSISTANT PROFESSORCARDIOPULMONARY PHYSIOLOGY

The Department of Physiology, Wayne State Uni-versity School of Medicine, is inviting applications forthe position of tenure-track assistant professor in the areaof cardiopulmonary physiology. Preference will be givento candidates with a strong background and researchinterest in cardiorespiratory physiology. The successfulcandidate will be expected to establish an ipdependentresearch program supported by extramural funding.Teaching responsibilities include the training ofgraduatestudents, and participation in departmental dasses formedical and allied health students. The target date forfilling the position is the winter of 1988. Salary will becommensurate with qualifications and experience. Sendcurriculum vitae, a description of research interests, andthe names of three references to: Dr. J. W. Phillis,Chairman, Department of Physiology, School ofMedicnc, Wayne State University, 540 East Canfield,Detroit, MI 48201, by 30 Junc 1987. An AffirmativeActionlEqual Opportunity Employer.

Applications are currently being accepted for a posi-tion at the level of ASSOCIATE PROFESSOR ORPROFESSOR in the Departmcnt of ExperimcntalTherapeutics and Grace Cancer Drut Ccnter at Ros-well Park Mcmorial Institutc. Candidates will be ex-pected to establish and lead a research program focusedon the identification of the mode of action of anticancerdrugs. Research and demonstrated leadership experiencein biochemical pharmacology with a strong interest incanccr therapy is required. Inquiries should be addressedto: Dr. E. Mihich, Roswell Park Memorial Institute,Buffalo, NY 14263. Equal Opportunity Employer.

AUDITORY RESEARCHEVOKED POTENTIAL STUDIES (ANIMALS)A nontenure-track, full-time research position is avail-

able immediately for a person with training (Ph.D.) andxperience appropriate to conduct evoked potential stud-

ies on awake and anesthetized animals with chronicallyimnplanted electrodes. Excellent opportunity to pursuebasic and applied study of the auditory system and tocollaborate with others in on-going studies ofthe anato-my, physiology, and histochemistry of the cochlea, audi-tory nerve, and brainstem. Interested persons shouldsend curriculum vitae, the names of three references, anda letter describing rescarch interests to: J. H. Mills,Department of Otolaryngology and CommunicativeSciences, Medical University of South Carolina,Charleston, SC 29425. The Univers is an AffirmativeAction/Equal Oppounity Employr, and encourages appli-ationsfiom minoritygoup membersAUDITORY RESEARCH-HUMAN SUBJECTSA nontenure-track, fill -time research position is avail-

able immediately. This position requires training (Ph.D.)and experience appropriate to conduct audiological, psy-chophysical, and evoked potential studies with humansubjects. Certification in audiology useful but not man-datory. CFY can be arranged. Excellent opportunities areavailable for collaboration. Current projects indude sin-gle-unit studies of the auditory nerve and brainstem,cochlear and neuroanatomy, histochemistry of the coch-lea, and evoked potential studies with infants and experi-mental animals. This position is an excellent opportunityto pursue basic and clinical studies in an active, multidis-ciplinary research setting with state-of-the art instrumen-tation. Interested applicants should send curriculum vi-tae, the names of three references, and a ietter describingresearch interests to: J. H. Mills, Department of Oto-laryngology and Communicative sciences, MedicalUniversity of South Carolina, Charleston, SC 29425.The Univeity is an AffirmativActionlEqual OpportunityEmployer, and encourages applicationsfrom minontygop

meber

ASSOCIATE Ph.D. with at least 8 years of back-ground research and publications in the biochemistry ofdevelopment, to perform research on the regulation ofhemopoiesis, to assist in the supervision of graduate andpostdoctoral students, to design and maintain scientificequipment, and to supervise laboratory computer work.Experience in the purification of membrane growthfactor receptors required 35 hours per week; salary:$34,000. Reply to: Dr. E. R. Stanley, Albert EinstcnCollege ofMedicine, Chanin 513, i300 Morris ParkAvenue, Bronx, Ncw York, NY 10461. An EqualOpportunity Employer.

ASSOCIATE V. ANALYTICAL CHEMIST withPh.D. in chemistry or related field or M.S. in chemistryor related field with a minimum of4 years of experiencein analytical chemistry. Experience in drug screeningand/or forensic sciences methodology using solid-phaseextraction, thin-layer chromatography, immunoassay,and mass spectrometry desirable. Duties relate to super-vision of, and participation m, analysis of drugs inbiological fluids. Submit resume by 24 April 1987 to:Dr. Charles R. Short, Department of VeterinaryPhysiology, Pharmacology and Toxicology, School ofVeterinary Medicine, Louisiana State University(I,SU), Baton Rouge, LA 70803. LSU is an EqualOpportunity Employer.

BEHAVIORAL NEUROSCIENCEResearch position available immediately for someone

with a background in behavior or neuroscience. Preferindividuals familiar with or willing to learn modemcellular and molecular techniques or studying brain-behavior relationships. Our research project concerns theinfluence ofgonadal hormones on neuroendocrine mech-anisms regulating mammalian reproductive behavior,and utilzes quantitative autoradiography, receptor as-says, immunohistochemistry, and neural tract tracingtechniques. Send curriculum vitae and the names, ad-dresses, and telphone numbers offour references to: Dr.Lynwood Clemens, Department of Zoology, Michi-gan State University, East Lansing, MI 48824.

BIOCHEMICAL ENGINEERING, University ofMaryland. Applications are invited for a faculty position(tenure) to be jointly held in the Chemical EngneeringProgram of the Department of Chemical and NuclearEngineering and the Agricultural Biotechnology Center,an iterdisciplinary research unit. Applicants should havean earned Ph.D. and a strong interest in research inbioconversion of agricultural products. Superior appli-cants at any rank will be considered although a reason-

ably senior person is desired. Candidates should submitcurriculum vitae and the names of three references to-Dr. Ted Smith, Director, Chemical Engineering Pro-gram, Department of Chemical and Nudear Engi-nering, university of Maryland, College Park, MD20742-2111. Applications will be accepted until theposition is filled; for best consideration, applicationsshould be submitted before 1 June 1987. The UniverityofMavlnd is an Equal OpportunitylAffirmative AcinEmJloyer and welomes applicationsfrom qualified minoitiesand women.

BIOCHEMICAL ENGINEERING POSITIONSThe University of California, Irvine, is recruiting for

tenure-track faculty positions at any level in BiochemicalEngineerm-R. The School of Engineering is movingtoward establishment of a new department to comple-ment a range of scientific endeavors in biotechnologywithin the University and in the adjacent biotechnologi-cal community. The opportunity to join in the buildingof this new department m a growing research universityin association with surrounding industry should be anaccltig prospect for scholars looking for new challenges.A Ph.D. in chemical engineering or related field isrequired. Responsibilities will include research andteaching at the graduate level. Specific areas of researchto include the following: cellular culturing systems,bioreactors, separation and purification processes, and/oranalytical momtoring methods. Please forward your let-ter of interest, curriculum vitae, and list of references to:Dean William A. Sirigano, Biochemical En nnSearch Committee, School of Engineering,Xniversi-qy of California, Irvine (UCI), CA 92717. UCI is anEqual OpportunitylAffirmat Aaton Employer.

PERSONNEL PLACEMENT 34517 APRIL I987

POSITIONS OPEN POSITIONS OPEN

K~~~~~~~~~~~~~~~~~The Naval Surface Weapons Center, located in subur-ban Washington, DC, is establishing a laboratory forresearch and development in the areas of molecularbiology and microbial genetics. Our Research andTechnology Department is seeking molecular biolo-gists, biochemists, bacteriologists, and biophysicists forpositions in this laboratory. Publication in the open liter-ature is expected.

Salary will be based on qualifications.

For further information, contact Dr. James F. Goff,commercial - (202) 394-2289 or AUTOVON -290-2289. Interested applicants should send a resume(or SF-171 if current or reinstateable Federal Govern-ment employee) including list of publications andpatents, and a detailed description of your experiencein the field to NSWC by May 8, 1987.

i'>SW~0 NAVAL SURFACE WEAPONS CENTERJ~ Attn: Code P60(S), Ms. Doris McNeel

10901 New Hampshire AvenueSilver Spring, MD 20903-5000

* An Equal Opportunity Employer 0

a U.S. Citizenship Required - II iiWe Said NO.SoYouCouldSayYES!IGEN, Inc. turned down a major pharmaceutical

firm's offer to purchase us because we believeIGEN can become one of the major diagnosticsand pharmaceuticals companies of the future.

ELECTROCHEMISTIf you are a Ph.D. in Electrochemistry or Electro-

analytical Chemistry with experience in modifiedelectrode surfaces, spectroelectrochemistry or

electrochemistry at microelectrodes, you maybe qualified for the challenge.The successful candidate will have working

knowledge of organic electrochemistry andthe electrochemical techniques necessary toelucidate electrode reaction mechanisms.IGEN welcomes discussions of these oppor-

tunities with curious qualified candidates whomay not be currently exploring employmentalternatives. Call in confidence to our Director ofInstrumentation (301) 984-7964 or send C.V. withsalary history to: IGEN, Inc., 1530 East JeffersonStreet, Rockville, MD 20852.

An EmerhgingI~NC. Biotchnoogy

An Equal Opportunity Employer

FACULTY AND STAFF POSITIONSBIOLOGY DEPARTMENTTEXAS A&M UNIVERSITY

Faculty Position. A tenure track position is available at any levelin the area of Molecular Genetics of Microorganisms. The successfulcandidate must have demonstrated significant potential to develop avigorous, extramurally funded research program. Researchers inyeast molecular biology are especially encouraged to apply. Contact:Microbiology Search Committee, Dr. Susan S. Golden.

Senior Scientist is sought to supervise a state of the art DNAsequencing and Synthesis Laboratory. Applicants must beexperienced with both Maxam and Gilbert and Dideoxy sequencingprocedures, and with automated oligonucleotide synthesis.Opportunity for pursuit of individual research interests and providingsequencing service and instruction for others. Ph.D. required, or atleast three years of direct participation in sequencing projects.Approximate salary $30,000, but commensurate with experience.Contact: Dr. Timothy C. Hall.

Electronics Repair and Maintenance Support Engineer. Applicantsmust have field experience in repair and maintenance of biologicaland biochemical laboratory equipment. Ability to design andconstruct required modifications to such equipment and conducttraining sessions is essential. Contact: Dr. Timothy C. Hall.

Additional Positions. Postdoctoral and Graduate Research Positionsare available within the department. Contact Dr. Timothy C. Hall.

Applications, including a C.V., a description of goals and interests,and names of three references with addresses and phone numbers,should be mailed directly to the contact person for each position atthe following address.

BIOLOGY DEPARTMENT, TEXAS A&M UNIVERSITYCOLLEGE STATION, TX. 77843-3258

Texas A&M University is an equal opportunity employer.

The Upjohn Company, recognized as a worldwide leader in pharmaceuticalresearch, is seeking applicants for the position of Research Scientist in theBiotechnology Product Development Group of the Control Division.The successful candidate will have experience in developing laboratory meth-odology to determine the presence of microbiological contamination in con-tinuous cell lines and recombinant proteins. In addition, this individual will beexpected to take responsibility for Control product development activities onall Upjohn vaccine products. This will include coordinating research effortsbetween scientists, serving as a representative on project teams, and provid-ing the rationale for product specifications.The candidate will join an inter-disciplinary team that is responsible for provid-ing data to address product registration issues on a worldwide basis. Theposition requires a Ph.D. in virology, microbiology, or clinical chemistry andexperience with modern diagnostic methods used in the identification of path-ogenic organisms. Good oral and written communication skills are required.Kalamazoo is a medium-sized Southwestern Michigan community with imme-diate access to a mix of excellent cultural, educational and recreational pur-suits, including numerous lakes and a four-season climate.For confidential consideration, call toll free 1-800-253-8600, ext. 3- 6767,(inside Michigan call collect 616-323-6767) to request an employmentapplication be sent to you. Please refer to Ad Number 20972-F when calling.

An Equal Opportunity EmployrI 0I

An Equal Opportunity Employer M/F.

p

DIRECTORBRAIN RESEARCH INSTITUTE

Applications and nominations are invited for a new Directorof the Brain Research Institute, University of California, LosAngeles. Of utmost importance in the candidate's qualifications isan outstanding, current research and publication record in neuro-biology. The candidate should have a strong interest in thedevelopment of interdisciplinary activities in neurobiology, awillingness to administer budgetary, personnel and related pro-cesses fairly and efficiently, and the ability to obtain appropriateexternal financial support for the Brain Research Institute.

The Brain Research Institute will reorganize into a series ofmajor laboratories consisting of groups of scientists with commoninterests. The Director of the Brain Research Institute will alsodirect one of these laboratories and, in consultation with anExecutive Committee, govern the Institute and develop excellencein multiple areas of neurobiology.

Applications or nominations including a complete curriculumvitae will receive full consideration and should be sent to:

Search Committee for Brain Research Institute Directorc/o Faye Porche', Administrative AssistantUCLA School of MedicineRoom 12-138Center for the Health SciencesLos Angeles, California 90024

The University of California is an Affirmative Action/Equal Oppor-tunity Employer.

BIOCHEMISTMerck Sharp and Dohme Research Laboratories,a world leader in thd development of ethical phar-maceuticals for human and animal health, is cur-rently offering an excellent career opportunityfor a biochemist to join the Department of BasicMicrobiology.The incumbent would develop and perform en-zyme and rec6ptor binding assays for thediscovery of pharmacologically active fermenta-tion products. Also, he/she would assist in thedevelopment of romputer programs for the man-agement of assay data.

A Ph.D. or equivalent in biochemistry or phar-macology with a strong background in enzyme orreceptor binding assays and purification of pro-teins is required. Experience with computers isdesirable.

Salary and benefits are excellent. Our location isRahway, New Jersey, 25 miles from New YorkCity. Interested applicants should submit acurriculum vitae to Luis F. Ballester, Merck Sharp& Dohme Research Laboratories, P.O. Box 2000,WBD-214, Rahway, New Jersey 07065. Equal Op-portunity Employer.

REQUEST FORRESEARCH GRANT APPLICATIONS

BIOCHEMICAL ANDMOLECULAR ASPECTS OFTHE REGULATION OF ION

TRANSPORT INEPITHELIAL CELLS

The Cystic Fibrosis Foundation invitesgrant applications to define and characterizethe biochemical and molecular aspects in-volved in the regulation of epithelial cell iontransport related to cystic fibrosis (CF), withspecific focus on post-receptor regulatorymechanisms.

This special request is intended to encourageinnovative, meritorious studies focusing onareas including but not limited to: molecular/biochemical identification of transport proteinsand associated regulatory elements; geneticmanipulation of transport models to studyregulation; identification of second messengerpathways and interrelationships among thesepathways; approaches to bypassing or mod-ifying altered transport mechanisms in CFcells. Applications must demonstrate potentialrelevance to CF.Awards will be made as grants-in-aid. Ap-

plicants may request up to $100,000 in totalannual costs (direct and indirect) for up to twoyears.

Interested individuals are encouraged to con-tact the Foundation to discuss the potentialrelevance of their work to the objectives of thisannouncement and to submit a letter of intentby June 1, 1 987. The deadline for submissionof applications is August 1, 1 987. Applicationmaterials are available from the

Cysic Cystic Fibrosis FoundationR~Flbross Arlington RoadFounrois Bethesda, Maryland 20814

(301) 951-4422

Repligen Corporation is a biotechnology company that develops and producesbiochemical and biocatalytic products for the health care, personal care andindustrial markets. We are seeking qualified candidates for the followingpositions:

Manager of Peptide ServicesTo coordinate the synthesis and analysis of peptides and develop quality controlcriteria and therapeutic proteins. This position requires either a B.S. with a minimumof 2 years' experience or a recent Ph.D. in:* Peptide mapping and purification by HPLC* Amino acid analysis by HPLC* Peptide synthesis* Peptide sequencing* Experience with chemical modification of proteins a plus.

Experienced Protein Purification/Process Development ScientistsAt Ph.D. and M.S./B.S. level. Requirements are:

* At least 2 years' experience in developing and scaling up methods forpurification of therapeutic proteins produced by recombinant techniques.

* Working knowledge of GMP manufacturing procedures.* Experience with bacterial fermentation of mamthalian cell culture a plus.

DNA Sequencing Research AssociateTo supervise DNA sequencing service including coordination of sequencing projects.Requirements are:

* B.S./M.S. in biochemistry/microbiology and at least 1-2 years' lab experience.* Extensive experience With DNA sequencing and computer organizationand analysis of sequence data.

* Thorough training in recombinant DNA technology.* Experience in project organization, technician supervision and operation ofa DNA synthesizer a plus.

Repligen offers a competitive salary, excellent benefits and equity partici$ation.Please submit cover letter, resume and references to: Personnel Director-RAD, OneKendall Sq., Bldg. 700, Cambridge, MA 02139. An Equal Opportunity Employer.

E T.7t.W-

ASSOCIATER & D DIRECTOR

CSLAUSTRALIA

CSL is Australia's leading manufacturer of liologi-cals and has a strong commitment to Researchand Development. CSL's major facilities are locat-ed at Parkville which is four kilometers from thecentre of Melbourne, and is in close proximity tothe University of Melbourne, the Walter and ElizaHall Institute of Medical Research and severalother institutions.

CSL is looking for a senior researcher with theability to manage, plan complex R & D activities,develop and implement strategies compatible withour corporate goals, adapt to changing technologi-cal needs, and motivate and direct a team ofresearchers. The right person will make significantcontributions to the identification of new businessopportunities, translate the results of scientific pro-grams into recommendations for corporate action,and make sure projects operate efficiently, effec-tively and economically.

This new position will be one of two AssociateR & D Directors who will each share responsibilityfor the R & D Group and manage their respectiveareas of activities and projects.

Required experience includes a tertiary qualifica-tion to medicine, veterinary science or a higherdegree in one of the biological sciences and aca-demic and/or industrial research experience andpossess ability or potential as a senior researchmanager.

We offer a competitive salary, removal expensesand associated benefits for this appointment whichwe would expect to make about mid-1987.

Please send a cv outlining your qualifications,description of scientific and research experi-ence and the names of two referees, to Mr. E.D.Eade, Personnel Director, Commonwealth Se-rum Laboratories, 45 Poplar Road, ParkvilleVic. 3052, Australia, by 15 May 1987. Telephoneenquiries may be made to Dr. Peter Schiff,R & D Director, +613-3891484.

*E L COMMONWEALTHSERUMLABORATORIES

An Affirmative Action/Equal Opportunity Employer

LaboratoryAssistant

Fermentation R&DDepartment

Pfizer Central Research has an immediate opening for alaboratory assistant in its Fermentation R&D Department.You will contribute to the elucidation of biochemical pathwaysfor a wide variety of fermentation products, including antibi-otics. Typical duties will include mutation/selection of organ-isms, enzyme isolation and manipulation of biochemicalpathways to improve production.Applicants should possess a BS or MS in Biochemistry,Microbiology or related field.In addition to a stimulating scientific environment, we alsooffer competitive compensation, benefit package and the op-portunity to live in an attractive Connecticut shore commu-nity. Please send resume and description of researchaccomplishments to: LorraineC. Corr, Personnel Associate,Pfizer Central Research, Eastern Point Road, Groton, Con-necticut 06340.

An equal opportunity employer

MOLECULAR BIOLOGISTSSouthern Research Institute has immediate positions availablefor qualified molecular biologists with post doctoral experience inthe following areas:

Eukaryotic Molecular Genetics. Prefer experience related tomolecular oncology/oncogene research. Must possess skills ineukaryotic cell transfection and expression techniques, DNAsequencing, blot hybridization, plasmid cloning/subcloning, genomiccloning, and other recombinant DNA techniques.

Prokaryotic Molecular Genetics. Prefer experience which alsoincludes some eukaryotic molecular genetics and gene expres-sion. Skills required in both basic and applied molecular biology/genetics, plasmid cloning, DNA sequencing, gene expression inprokaryotic systems/eukaryotic systems, and molecular mecha-nisms involved in microbial pathogenesis.

Duties may involve work on existing and proposed projects,developing expanded programs in oncogene/molecular carcino-genesis research and/or obtaining independent research supportin own area of interest.

Located in a 20-acre complex and with a staff of over 700,Southern Research Institute is a diversified contract researchorganization in its fifth decade of operation. The Birminghamarea, with a population of one million, offers a mild four-seasonclimate, lower-than-average cost of living, diverse recreationaland cultural opportunities and a variety of convenient housingalternatives. To apply, send c.v. to:

Denise D. JohnsonSOUTHERN RESEARCH INSTITUTE

*| - Personnel Office, Dept. B188P.O. Box 55305Birmingham, AL 35255-5305

POSITIONS OPEN

BIOCHEMISTRY/IMMUNOLOGYThe School of Pharmacy, Campbell University,

invites applications for a 12-month, tenure-track positionat the level of assistant or associate professor, begnning 1August 1987. Applicants should have a Ph.D. and broadtraining in biochemistry and inmmunology. The salarv isnegotiable and commensurate with qualifications. Thesuccessful candidate will participate in the teaching ofbiochemistry and immunology in the professional curric-ulum. Excellence in teaching is expected. Applicantsshould submit curriculum vitae, a statement of researchand teaching goals, and three letters of reference to: Dr.Harry Rosenberg, Chairman, Department of Phar-maceutical Sciences, School of Pharmacy, CampbellUniversity, Buies Creek, NC 27506.

An Equal Opportunity Employer

BIOLOGICAL SCIENCES. Teach seed plant anat-omy and physiology and a survey course covering algae,fungi, and plants. Participate in departmental GeneralBiology sequence. Initiate a program of-undergraduateresearch in agriculture and plant biotechnology. Ph.D. inbiology, botany, or agricultural discipline with interest inundergraduate teaching. Instructor or assistant professorbased on experience and qualifications. Send letter andresume by lMay 1987, to: Dr. Carl Hoagstrom,Chairman, Department of Biological Sciences, OhioNorthern University, Ada, OH 45810. AffirmativeActionlEqual Opportunity Employcr.

CARDIOVASCULARELECTROPHYSIOLOGIST ANDMOLECULAR BIOLOGIST

The Department ofPhysiology, University ofMani-toba, invites applications for two positions from investi-gators in the field of experimental cardiology to beappointed at the level of ASSISTANT PROFESSOR(contingent appointment) in the Division of Cardiovas-cular Sciences. The applicant must have a M.D. or Ph.D.degree; and have 2 years of experience. Applicants withbackgrounds inclcctrophysiology and molecular biologyare encouraged to apply. The successful candidates willbe expected to compete for local and national scholarshipawards (for example, MRC) and develop their indepen-dent research programs as well as collaborate with othermembers of the department. Teaching in a graduateprogram will be a requirement. Please submit a copv ofyour curriculum vitae including an outline of yourresearch interests and arrange for three letters of refer-ence to be sent to: Dr. Henry G. Friesen, Professorand Head, Departnent of Physiology, Faculty ofMedicine, University of Manitoba, W mnnipeg, Mani-toba, R3E 0W3 Canada. Deadline for application is 30June 1987. Both men and women are encouraged to apply.In accordance with Canadian Imm,isration requirements,this advertisement is directed to Canadian citizens andpcrmanent residents of Canada.

CHAIRANDEPARTMENT OF MICROBIOLOGY

LOYOLA UNIVERSITYSTRITCH SCHOOL OF MEDICINE

The Stritch School of Medicine, Loyola Universitv ofChicago, invites applications and nominations for theposition ofChairperson ofthe Department ofMicrobiol-ogv. The candidate should possess a Ph.D. or equivalentdegree in microbiologv, have an established and activeresearch program, have a commitment to medical andgraduate education, and have had previous administra-tive experience. Individuals with a strong background inmolecular biological techniques are encouraged to sub-mit their applications. With an ongoing Molecular Biolo-gy Graduate Program and a new Macromolecular Facili-ty, the Stritch School of Medicine has a strong commit-ment to molecular biological research. Currently, thefaculty of the department is pursuing research in: molec-ular biology, cellular immunology, prokaryotic and eu-karyotic genetics, virology, immunochemistry, microbialphysiology, pathogenic mechanisms, and mycology. Ap-plicants should send curriculum vitae and the names ofthree references by 1 July 1987 to: Dr. John X. Thomas,Jr., Chainnan, Search Committee for Microbiology,Stritch School of Medicine, Loyola University ofChicago, 2160 South First Avenue, Maywood, IL

60153. Loyola Univesity of Chiago, Strtch School ofMedicine is an Affirnative ActionlEqual Opportunity Em-ployer.

I7 APRIL I987

CHAIRDEPARTMENT OF BIOLOGICAL SCIENCES

COLLEGE OF LIBERAL ARTSWAYNE STATE UNIVERSITY

We seek nominations, including self-nominations, ofpersons actively engaged in research to chair this Depart-ment, which encompasses a broad range of the lifescience subdisciplines. The Department has 28 facultymembers and approximately 130 graduate students inthe Ph.D. and M.S. programs. A new research building isplanned for occupancy in late 1989. The position isavailable as early as summer 1987 but may be deferred tono later than August 1988. An attractive salary, substan-tial start-up funds, etc. will be negotiated. Please sendcurriculum vitae and other pertinent material to: Profes-sor Henry V. Bohm, Chair, Selection Advisory Com-mittee, Department of Physics, Wayne State Univer-sity, Dctroit, MI 48202. Affirmative Action/Equal Op-portunity Employer.

CHAIRMANDEPARTMENT OF MICROBIOLOGY AND

IMMUNOLOGY

The Medical University ofSouth Carolina is seekingapplicants for the position of Chairman of the Depart-ment of Microbiology and Immunology. An individual issought who has the experience, desire, and ability toprovide strong administrative leadership, direct an activeresearch program, and organize and supervise teachingprograms for medical students and graduate students.The candidate should be an established investigator in an

area of contemporary microbiology or molecular biolo-gy. New resources will be made available to develop astrong department which is expected to play a major rolein the basic science programs of this institution. Thesecurrently include ongoing development of centers inmolecular and structural biology, cancer and cardiovas-cular disease. Curriculum vitae and names of threereferences should be sent to: W. Edmund Farmr, M.D.,Chairman, Microbiology Search Committee, Infec-tious Diseases Division, Medical University of SouthCarolina, 171 Ashlcy Avenue, Charleston, SC 29425.An Equal Opportunity MIF AffirmativeAtion Employer.

DEAN, COLLEGE OF PHARMACY, WASH-INGTON STATE UNIVERSITY. Washington StateUniversity invites applications and nominations for theposition of Dean, College of Pharmacy. The position is

available 1 July 1987. The University is located atPullman, and enrolls approximately 16,000 fiul-timestudents with approximately 200 students in the College.The College's 19 faculty provide vigorous undergraduateand graduate programs leading to the Bachelor of Phar-macy and the M.S. and Ph.D. in pharmacology/toxico-logy. There are approximately 35 graduate students inthe interdisciplinary pharmacology/toxicology progam.The college recently moved to a new facility. A canddatefor the position should have earned a doctorate in a

pharmaceutical or science discipline. Desirable qualifica-tions include a degree in pharmacv, experience withteaching and curriculum development at the undergradu-ate and graduate level, demonstrated research achieve-ments, and an ability to relate to pharmacy practitioners.Salary dependent upon qualifications. Application dead-line is 4 June 1987. Applications should include a currentresume and the names and addresses of five references.Applications and nominations should be sent to: CharlesD. Barnes, Chair, Dean of Pharmacy Screening Com-mittee, 205 Wegner Hall, Washington State Univer-sity, Pullman, WA 99164-6520. Washington StateUniversity is an AffirmativeActionlEqual Opportunity Em-Ployer.DIRECTOR-Center for Great Lakes Studies/

Great Lakes Research Facility University of Wiscon-sin-Milwaukee (UWM). Major research unit of TheGraduate School at UWM seeks applicants for a directorto develop and promote interdisciplinary research pro-grams, manage the research facility, and foster expansionof research activities and laboratory facilities. Must havePh.D., qualifications for tenured faculty appointment,record of research achievement in lake and ocean scienceor technology, and management experience in marineresearch programs. Salary competitive. Apply with letter,curriculum vitae, names, addresses of three references by15 June 1987 to: George W. Keulks, Dean, GraduateSchool and Research, P.O. Box 340, University ofWisconsin-Milwaukee Milwaukee, WI 53201.An Equal Opportunity/Affirmative Action Employer.

UNIVERSITY OF QUEENSLANDEqual Opportunity in Emplkyment is Univerity Policy

CHAIR IN ZOOLOGYApplications are invited from distinguished scientists

with high academic qualifications and tertiarv level expe-rience in teaching and research in the field ofterrestria ormarine biology.The appointee is expected to provide academic leader-

ship in the development of his or her discipline, and inthe scholarly activities of the department, particularly thepromotion of high standards and encouragement ofquality research and postgraduate studies. The appointeeshould be prepared to accept a significant amount ofadministrat've responsibility within the department, in-cluding terms of headship which are applicable to allpermanent members of the academic staff under Univer-sity poficy.

Salary per annum: A$58349. Closing date: 1 June1987. Reference No. 16887Additional information and application forms may be

obtained from: The Director, Personnel Services, Uni-versity of Queensland, St. Lucia Queensland 4067,AustraliaCHEMIST/RESEARCH ASSOCIATE: Perform

experimental research in the synthesization of polyfunc-tional monomers containing photolabile units; imagingby photo-decoupling of cross-links. Ph.D. in chemistrywith coursework in design, synthesis characterization,and application of high-temperature photoresists andpolymer chemistry required. Forty hours per week;$19,000 per year. Mail resume to: NYS Job Service,JO#NY8006933, 175 Remsen Street, 2nd Floor,Brooklyn, NY 11201.

CHIEF OF STAFF-The Veterans AdministrationMedical Center, Portland, Oregon, is seeking aCHIEF OF STAFF for our three-division general medi-cine and surgery facility. We hope to recruit an activeclinician with administrative experience and a record ofresearch accomplishments. We will occupy a new 490-bed acute care hospital and research center in 1987. Anew outpatient clinic and 120-bed nursing home careunit are in full operation. Please send nominations andapplications to: James Metcalfe, M.D., Chairman,Search Committee, clo Medical Staff Coordinator(11), VA Medical Center, P.O. Box 1034, Portland,OR 97207 by 1 June 1987. The VeteransAdministrationis an Equal Opportunity Employer.

COORDINATORSLEEP DISORDERS CLINICAL

RESEARCH CENTERApplications are sought for the position ofcoordinator

of the newly established Eleanor Dana Sleep DisordersClinical Research Center ofthe University ofPennsyl-vania. The coordinator will be accountable to an Execu-tive Group of sleep scientists and will be responsible forsupervising operation of the Research Center includingimplementation of specific protocols and data analvsis.The studies to be performed will all be in humansubjects. The Center will employ research technicianswho will report to the Coordinator for supervision andtraining. Applicants should have a Ph.D., be familiarwith psychophysiological recording (preferably humansleep recording), have at least basic computer skills, andbe interested in pursuing clinical research for a period of1 to 3 years. Salarv depends on previous experience.Applicants should send resumes with names of threeprofessional references to: Mr. Daniel C. Barrett, SlepCenter Search Committee, 975 Maloney Building,Hospital of the University of Pennsylvania, 3400Spruce Street, Philadelphia, PA 19104-4283. Affir-mative ActionlEqual Opportunity Employer; MIF.

ENDOWED CHAIR. Department of Psychiatryand Biobehavioral Sciences, U0niversity of California,Los Angeles (UCLA) School ofMedicine, seeks appro-priate candidates for Della Martin Chair in Psychiatry,endowed professorship for distinguished academic psy-chiatrist (English-speaking, eligible California licensure)committed to research especial[y on major mental illness-es of adolescents and young adults (for example, schizo-phrenia). Send curriculum vitae and letter discussingcareer goals to:

Arnold B. Scheibel, M.D., ChairmanDella Martin Search Committee

UCLA Neuropsychiatric Institute, B8-262760 Westwood Plaza

Los Angeles, CA 90024

349

POSITIONS OPENPOSITIONS OPEN

Micro Chemi Luminescent AssaySystems... MCLAS Technologies,Inc. offers the opportunity to pursuescientific careers in a stimulatingenvironment. We are seeking ex-perienced people interested inbecoming a part of a rapidlyexpanding company. There arecurrently several openings in thefollowing areas:

FOOD MICROBIOLOGIST -TECHNICAL SERVICESB.S. degree in Microbiology/FoodScience. 3-5 years industry experiencein direct microbiological analysis offood products according to AOAC,USDA, FDA procedures. Immuno-chemnisty and quality controlbackground desirble. Individualwill ultimately be responsible forproduct technical service withina region. Travel required.

MICROBIOLOGIST/IMMUNOLOGISTM.S. in Microbiology, Immunologyor related discipline. 3-5 years ex-perience in tissue culture techniquesand animal studies. Previous workwith macrophages desirable.

PRODUCHION MANAGEMENTB.S. and/or M.S., 8 to 10 yearshands-on experience in diagnosticsmanufacturing. Background shouldinclude fermentation, filtration,lyophilization, coating, filling,packaging and sterilization.

RESEARCH ASSISTANTSB.S. in Microbiology with 3-5years experience in virology andbacteriological research.

INSTRUMENTATION DESIGNENGINEERB.S. Electrical Engineering with 5years experience in digital andmicroprocessor design. Previousexperience with photomultipliertube technology desirable.

We offer competitive salaries, benefitsand stability for future development.Please send a resume, bibliographyand references to:

MCLAS Technologies, Inc.18585 Sigma Road,

San Antonio, TX 78258

Merck Sharp & Dohme Research Laboratories is currently offering several excellentcareer opportunities for Molecular Biologists/Cell Biologists to join the expandingDepartment of Cellular and Molecular Biology.

MOLECULAR BIOLOGISTSResponsibilities for these positions will include the utilization of a broad spectrumof techniques, including construction of cDNA and genomic DNA libraries, DNA/RNApreparation, blot analyses, DNA sequencing, and transfection and culturing of mam-malian cells.

An M.S. or B.S. degree in Biochemistry, Molecular Biology, or the equivalent with atleast 2 years of broad and significant experience in molecular biology are required.

CELL BIOLOGISTResponsibilities for this position will include maintenance, characterization andanalEsis of mammalian and invertebrate cultured cell lines, serum-free mediadevelopment, scale-up culture, and cell and media harvesting and processing. In ad-dition, molecular biological procedures, such as DNAIRNA preparation, plasmid vec-tor construction, DNA transfection, and transient and stable gene expressionanalysis will be performed. These techniques will be applied to the analysis and ex-pression of genes of potential pharmaceutical interest.

An M.S. or B.S. degree in Cell Biology, Biochemistry, or the equivalent, with at least2 years of significant experience in mammalian cell culture are required. Experiencein molecular biological techniques is a plus.Excellent salary and benefits programs accompany these positions at our newresearch building in Rahway, New Jersey. Please send your resume, three profes-sional references whom we may contact, and salary requirements in complete con-fidence to: Mr. Jacques P. Kueny

Me9k Sharp & Dohme..earch LaboratoriesResearch Personnel (8MomL1)P.O. BOX 2000 RallwaV, NJ 07065I o ~~~~~EEIAV/Epoe

ME KE

THE AUSTRALIAN NATIONAL UNIVERSITY. Applications areinvited from suitably qualified men and women forappointment as PLANT CELL AND MOLECULAR BIOLOGISTSin the RESEARCH SCHOOL OF BIOLOGICAL SCIENCES.Several research posts (Postdoctoral Fellow (PDF) orResearch Fellow (RF)) are available to support andaugment a major new program focused on Arabidopsis.They are: a PDF to study genetic aspects of production,selection and characterisation of mutants; a PDF to selectand study mutations affecting allocation of seed andphotosynthate resources toward growth; a PDF to charac-tense mutations affecting C02 transport and photosynthe-sis in physiological, biochemical and molecular terms; aPDF to study the genetic basis of regeneration in tissuecultures, particularly the role of the cytoskeleton and toundertake work on transformation; and a PDF or RF formolecular studies of morphogenesis and the cytoskeletonand calcium regulatory systems. A PDF (or RF) is alsoavailable to work in an associated program on grasssystematics and evolution, aimed at complementing thepresent work of the Taxonomy laboratory on the broaderaspects of grass classification. Relevant experience incellular/molecular/genetical/biochemical research is de-sirable. Starting dates are negotiable in the period mid-1987 to mid-1988. Further particulars are available fromthe School Secretary, Research School of Biological Sci-ences. Closing date: 15 May 1987. Ref BS: 12.3.1. Salarywill be in accordance with qualifications and experiencewithin the range: Postdoctoral Fellow Grade 1 (at a fixedpoint) $A24,013 - $A27,507 p.a.; Research FellowWA27,859 - $A36,000 p.a. Appointment will be: ResearchFellow normally up to three years with the possibility ofextension to maximum of five years; Postdoctoral Fellownormally two years, with the possibility of extension tomaximum three years. Superannuation, maternity leaveand assistance with travel available. The Universityreserves the right not to make an appointment or to makean appointment by invitation at any time. Applicantsshould quote the reference number when submittingapplications to R.V. Dubs, Registrar, GPO Box 4, Canber-ra, ACT, 2601 Australia. THE UNIVERSITY IS AN EQUALOPPORTUNITY EMPLOYER.

United StatesDepartment ofAgriculture

ric Agricultur

ResearchvService

AGRICULTURAL RESEARCH SERVICE is seekinginnovative scientists for challenging positions inbiochemistry research at the Northern RegionalResearch Center. Three positions will be avail-able this Fall as part of an expanding teaminvestigating microbial and enzymatic interac-tions with carbohydrate polymers from plants:

1. POLYSACCHARIDE BIOCHEMIST (GS-1 1/12)to study novel enzymatic approaches for intro-ducing unusual functionalities into complex car-bohydrate polymers. (Position No. 1W2560);

2. ENZYMOLOGIST (GS-11) to study carbohy-drate modifying enzymes from microbial sources.(Position No. 1W2561); and

3. BIOCHEMIST (MICROBIOLOGY) (GS-11) tostudy substrate recognition and attachment phe-nomena between microorganisms and insolublesubstrates. (Position No. 1W2562).

Position (1) is a permanent position. Positions(2) and (3) are Research Associates with amaximum appointment of 4 years. PhD or equiv-alent required for each position. Salaries: GS-1 1,$27,172; GS-12, $32,567. The Northern Re-gional Research Center is a large, well-equippedmajor research facility of the USDA, housingmore than 320 scientists and support personnel.To apply send resume and names of threereferences before June 1, 1987 to: Dr. J. Mi-chael Gould, USDA/ARS Northern Regional Re-search Center, 1815 N. University Street, Peo-ria, IL 61604. Applications in response to this admust be marked 7N005. Please specify clearlythe position for which you are applying. TheUSDA/ARS is an Equal Opportunity Employer.

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The Board of Regents of theUniversity of Nevada System

PRESIDENTDesert Research Institute

The Board of Regents of the University of Nevada System invitesapplications and nominations for the position of President of theDesert Research Institute. This autonomous statewide divisionof the university system conducts research programs in atmos-pheric sciences, water resources, energy and environmental en-gineering, social sciences and biological sciences funded by bothgovernmental and private sources. Established in 1959, the In-stitute has a current annual budget of $12 million and a facultyof 100 professionals. There is a close association between insti-tute research and university graduate programs. The Presidentreports through the Chancellor to the Board of Regents; the po-sition is equivalent to President of the other university campuses.The President is responsible for management of a diverse butcoordinated research institute, for relationships with the re-search sponsors, the university system, the Board of Regents,the legislative and executive branches of the federal and stategovernment and should be prepared to play an active role in as-sisting economic diversification in the state of Nevada. Qualifi-cations include demonstrated management and leadership abili-ties, a distinguished record of achievement in scientific or engi-neering research, a broad background in the funding and con-duct of research, and proven effectiveness in the areas of gov-ernmental, university, and community relations. A record ofsuccessful and substantial institutional fundraising is important.The committee will begin a review of applications with vita in-cluding a list of publications and summary of career researchand support, on May 1, 1987. To apply, or for further informa-tion, contact: DRI Presidential Search Committee, University ofNevada System, 405 Marsh Avenue, Reno, Nevada 89509. Anequal opportunity, affirmative action employer.

ANALYTICAL BIOTECHNOLOGY

MACROMOLECULAR ANALYSIS

lhe Drug Metabolism Department ofHoffmann-La Roche is expanding, creatingmethods development opportunities for the

isolation, characterization and quantification of novelpeptide/protein drugs in clinical samples.

SR. SCIENTISTYou will be responsible for validated methods develop-ment. Requirements include Ph.D. and postdoctoralexperience in Chemistry, Biochemistry, Immunology ora related field. The combination of Immunoassay, Bio-assay and Chromatographic based quantification exper-ience is highly preferred. Please respond to EleanorM. Malone, Dept. DL-1.

ASSOCIATE SCIENTISTYou will assist in the above methods development,and must possess BS or MS in Chemistry, Biochem-istry, Immunology or a related field, and 3-5 years ofrelevant experience. Please respond to Fran Newman,Dept. DL-2.

If selected, you will be rewarded with an attractivecompensation package including salary, bonus andprogressive benefits. For confidential consideration,please send your resume and salary (only thoseresponses including present salary will be acknowl-edged), to the appropriate person and department at:Hoftmann-La Roche Inc., Nutley, New Jersey 07110.

are an equal opportunity employer.

Hoffmann-La Roche

Working Today ForA Healthier Tomorrow.

NewZZand I[Daily Research Insitute|

D I R E C T O RApplications are invited for the vacancy created by the retirement of the Director of theNew Zealand Dairy Research Institute from early January 1988. The appointment will befor an initial period of five years, with renewal(s) by mutual agreement.

The Institute undertakes Fesearch and development in all matters related to theconversion of milk into dairy products, including the market-oriented requirements of theNew Zealand Dairy Board, through development work in new products and processes andfunctional variations of traditional ones. Other major activities include work formanufacturing dairy companies and the implementation of research findings.Excellent laboratories and pilot plant are situated at Palmerston North adjoining theMassey University campus and adjacent to three major Divisions of the New ZealandDepartment of Scientific and Industrial Research.

The Institute's staff totals 235 (105 Research Officers). Current annual expenditure,including the associated small-scale dairy plant, is about NZ$11.4 million.

Applicants should have a good degree in a relevant field, and have shown ability andleadership in research and the management of science/technology at a senior level. Thisexperience should preferably include involvement in the identification and development ofresearch projects in a commercially orented environment.

The position carries a good level of remuneration related initially to qualifications andexperence. Generously subsidized superannuation and a car are available.

Further information may be obtained from:

The DirectorNi.Z. Dairy Research InstittePrivate BagPalmerston NorthNEW ZEALAND

Applications, marked "Confidential" and addressed to The Chairman at the aboveaddress, should include personal details, curriculum vitae and the names of threereferees. Applications close on 15 May 1987.

D

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POSITIONS OPEN

DIRECTOR OF CLINICAL TRIALSInternational research organization concentrating on

family health (including familv planning) program seeksa Director for its Clinical Trials Group. Successful candi-date will have an M.D., plus a master's level in pharma-cology or a Ph.D. in pharmacology, pharmaceutics, orclosely related field with a minimum of 5 vears ofexpenence in planning, executing, and evaluating clinicaldrug development studies. Ph.D.'s in biostatistics withextensive clinical research management experience will beconsidered. Experience in drug regulatory affairs desir-able. Must be well published. A working knowledge of atleast one Third World country's health research capabili-ties and needs desirable. Demonstrated experience in

preparation and review of research materials required.Superior location for good living and intellectual stimu-lation in Research Triangle area of North Carolina. Sendresume to: President, Family Health International, 1

Triangle Drive, Research Triangle Park, NC 27709.An Equal OpptunityAffirmativeAtAion EmpJyer MtFIH.

DIRECTOR OF RESEARCH RESOURCES FA-CILITY-D.V.M. licensed to practice in the District ofColumbia with postgraduate training in laboratory ani-mal medicine. ACLAM Diplomate or eligibility forcertification desirable. Demonstrated interest and com-

petence in research, administration, and communicativeskills. The Director is responsible for the management,development, and accreditation of a new "state-of-the-art" animal facility consisting of approximately 25,600gross square feet of floor area which serves the researchand educational needs of the Georgetown UniversitvMedical Center. The position has administrative, secre-tarial, and staff support. The successful candidate isencouraged to develop his/her own research program andparticipate in collaborative research. Salary and academicappointrnent are commensurate with experience andqualifications. Position is available immediately. Sendcurriculum vitae and names of references to: Dr. PeterA. Kot, Chairman, Search Committee, Department ofPhysiology and Biophysics, Georgetown UniversitySchools of Medicine and Dentistry, 3900 ReservoirRoad, NW, Washington, DC 20007. Geogetown Uni-vei*yis An Equal OppmTunityAfinniveAcimn Emp.oyer.

FACULTY MEMBER/COLLEGE OR UNIVER-SITY: CELLULAR IMMUNOLOGIST: primarilvresearch position (1 year, renewable annually) to beoffered at $25,000 to $32,000 per year depending onexperience and qualifications; 40 hours per week. Re-sponsibilities include: developing effective immunologi-cal agents and methods against livestock diseases cocci-diosis and cryptosporidiosis; conducting and publishingindependent research on cell-mediated immunity (CMI)to parasitic protozoa; supervising and advising graduatestudents and staff in the laboratory; assisting in teachinggraduate seminars. Required qualifications: Ph.D. inimmunology; 3 years of postdoctoral, research assistant,or professional research expenrence in T cell-, macro-

phage-, and lvmphokine-mediated immunity; expertisem cell-mediated immunitv to parasitic protozoa of hu-mans and livestock; and an established record of publica-tion in peer reviewed journals. Send a letter of applica-tion, curriculum vitae, and names and addresses of threereferences to: Bozeman Job Service, ATIN: NancyLeafdak, 121 North Wilson Avenue, Bozeman, MT59715. Refer to Job #0518120. An Equal Opporeuni-tylAffirmative Action Employer.

FACULTY POSITIONUNIVERSITY OF CALIFORNIA, IRVINEThe Department of Physiology and Biophysics is

seeking a faculty member with research interests inmolecular, cellular, and/or structural aspec of biology.The appointment will be at the ASSISTANT PRO-FESSOR (tenure-track) level commencing fall, 1987 orwinter, 1988. The successful candidate will be expectedto conduct a vigorous, independent research programand contribute to the teaching of medical and graduatestudents. Applicants should have postdoctoral experienceand demonstrated abilitv as a creative scientist. Sendcurriculum vitae, a brief description of research interestsand the names of three referees to: Professor StephenH. White, Chairman, Department of Physiology andBiophysics, Univcrsity of California, Irvine, CA92717.

The University of California, Irvine is an AffirmativeAction/Equal Opportunity Emplyer.

FACULTY POSITION. The Department of Biolo-gy at Viterbo College invites applications for a 1-

year/possible tenure-track position at the assistant profes-sor (Ph.D.) level. The successful candidate should haveexperience in teaching microbiology, biochemistry, andimmnunology. Application, including curriculum vitae,three letters of reference, undergraduate and graduatetranscripts, and a one-page statement of teaching andresearch interests should be sent by 1 May 1987 to: Dr.Linda Malick, Chairperson, Department of Biology,Viterbo College, 81SSouth 9th Street, LaCrosse, WI54601.

Viterbo Collge is an Equal OpportunitylAffirmative Ac-tion Employer.

FOREST SCIENTISTQUALITY ASSURANCE SPECIALIST

Northrop Services, Inc. (NSI) is seeking a qualifiedindividual to assist in the Quality Assurance (QA) Pro-gram for research on the effects of atmospheric deposi-tion on forest ecosystems, part of the National AcidPrecipitation Assessment Program. The individual willinteract with researchers, organize and interpret perform-ance evaluations, audit research sites, and prepare QAreports. The QA Specialist will be located near Philadel-phia, Pennsylvania. M.S. degree or equivalent experiencem forest science or related environmental science isrequired. Laboratorv experience required. Familiaritywith forestrv field measurements and greenhouse opera-

tion required. Communication skills, general knowledgeof QA, and familiaritv with atmospheric depositionresearch is desirable. Salarv commensurate with qualifica-tions. Send resume and names of three references by 1

May 1987 to:

Ms. Susan CareyNorthrop Services, Inc.200 SW 35th StrectCorvallis, OR 97333

NSI is an AffirmativeActonlEqual Opportunity Employer

GLYCOPROTEIN/CARBOHYDRATEBIOCHEMIST

POSTDOCTORAL POSITION available for per-

son trained in glvcoprotein and/or carbohydrate bio-chemistry (particularly chromatographic methods forsugars, oligosaccharides, and glycopeptides) to partici-pate in ongoing research concerning role of roteinglycosvlation in photoreceptor membrane morphogen-esis and retinal degenerations. Send curriculum vitae,recent repnnts, and names of three references to: Dr.Steven J. Fliesler, Bascom Palmer Eye Institute, Uni-vcrsity of Miami School of Medicine, P.O. Box016880, Miami, FL 33101.

MICROSURGEON

University of Pittsburgh Department of Surgery isseeking an outstanding individual to join the researchefforts of its Microvascular Surgical Transplantation Lab-oratory. The microsurgeon will perform heterotopicheart transplants in rodents along with pre- and post-operative immunological monitoring of grafted animals.The ideal candidate will possess a MS. degree withextensive experience in all aspects of microsurgery. Abackground in immunology is essential. Salarv to low$20's. Send resume to: Paul J. King, 172 ThackerayHall, University of Pittsburgh, PA 15260. AffinnativeActionlEqual Opportunity Employer.

MOLECULAR BIOLOGIST

The Central Laboratory for Human Embryology inthe Department of Pedaatrics has a position at theresearch assistant professor level for a molecular biolo-gist. Qualifications: M.D., Ph.D., or M.D./Ph.D., withpostdoctoral experience in recombinant DNA technolo-gy. Candidate will be expected to direct a researchprogram using human embryonic/fetal tissues and toparticipate in an NIH-funded tissue distribution pro-gram. Candidate will also be expected to interact withthree faculty members whose research interests are in thefield of teratology and to participate in a course entitledHuman Embryologv and Teratologv offered each year.Applicants should send their curriculum vitae along witha list of three scientists who might supply supDortingletters to: Dr. Thomas H. Shepard, Hcad, Centr;aLaboratory for Human Embryology, Department ofPediatrics RD-20, University ofWashington, Seattle,WA 98195.

IMMUNOCHEMISTRYSeragen Diagnostics, Inc., an Indianapolis-based

manufacturer of instruments and reagents, has an imme-diate opening for an experienced scientist within theimmunoassav products group. The position encompassesbroad responsibilities from conception of technical ideasand reduction to practice to market introduction of newproducts.The individual we seek should have 3 to 5 years of

expenence in immobilization of biological material inaddition to experience mi non-isotopic immunoassaydevelopment. The successful candidate should be highlyself-motivated and goal oriented with strong oral andwritten communcation skills. A Ph.D. is desired, but notnecessary providing stated qualifications are satisfied.

Seragen Diagnostics offers competitive salary (com-mensurate with experience) and benefit programs. Forprompt confidential consideration, please send resumeand salarv history to: Personnel Manager, SeragenDiagnostics, Inc., P.O. Box 1210, Indianapolis, IN46206.

Equal Opportunity Employer.

MOLECULAR BIOLOGIST/GENETICISTVivigen, Inc., a leader in genetic testing, has an

immediate opportunitv for a scientist with a Ph.D. to setup and run a DNA probe laboratory. The companycurrently operates the largest chromosome analysis labo-ratory m the country.

Candidates must be familiar with all aspects ofmolecu-lar biology, especially nucleic acid hybridization andRFLP analvsis. The successful candidate will direct an

effort to industrialize DNA probe analysis, making theaccurate processing of large sample volumes possible.This technology will be applied to a number of gcnetictests. This position will also involve working with aca-demic and industrial scientists in the transfer oftechnolo-gv to Vivigen.

Vivigen is located in Santa Fe, New Mexico, in thesouthern tip of the Rockv Mountains. The region is richin culture, and has abundant resources for outdoorrecreation. Santa Fe is an hour away from both the LosAlamos National Laboratory and the University of NewMexico Medical School, providing opportunity for inter-action with the scientific community. The company willprovide a salarv commensurate with experience and anattractive package of benefits. Please contact: Gregg L.Mayer, Ph.D., at 505-988-9744, or at the followingarss, for more information:

Vivigen, Inc.435 St. Michael's DriveSanta Fe, NM 87501

NEUROPHYSIOLOGY RESEARCH position toconduct voltage-clamp studies on neurons in gastropodmollusks. Work will be in conjunction with behavioral,pharmacological, and histological studies, and will over-lap with studies dealing with parallel processing. Ph.D.or equivalent research experience is required. Computerexperience is desirable. Salary: $18,000 to $20,000.Available 1 July 1987 to 9 January 1989; extensionpossible. Closing date: 10 June 1987. Send three lettersof reference and curriculum vitae to: George J. Mpitsos,Oregon State University, Mark 0. Hatfield MarineScience Center, Newport, OR 97365. Equal Opportun-itylAffimaive Action Employer.

SCIENCE, VOL. 236

MOLECULAR IMMUNOGENETICSWe are seeking an individual to coordinate

development of a histocompatibility typing labusing nucleic acid hybridization technology.This program will involve the use of polvmerase-catalyzed gene amplification, and of nonradioac-tive probes. The position will entail interactionwith the immunogenetics section of the researchdivision. Minimum requirements are an M.S. orequivalent with expenence or a recent Ph.D.Please send resume to:

Richard H. Aster, M.D., PresidentThe Blood Center of Southeastern Wisconsin

1701 West Wisconsin AvenueMilwaukee, WI 53233

352

POSITIONS OPEN POSITIONS OPEN

PHARMACEUTICAL

RESEARCHASSOCIATES

The Squibb Institute for Medical Research, a recognizedleader in the research and development of noveltherapeutic agents, has several exciting opportunitiesavailable in the Department of Pharmacology. Respon-sibilities will be to conduct experiments in animals in-volving the measurement of cardiovascular and renalfunctions. Qualifications for these positions include a B.Sor M.S. in a biological science plus at least two years ex-perience involving conscious animal models, smallanimal surgery and experimental hypertension.The Squibb Institute is located in Princeton, NJ, apleasant semi-rural setting convenient to both Philadel-phia and New York. In addition to an excellent salary andcomprehensive benefits package, we can offer the oppor-tunity for exceptional scientists to pursue stimulatingcareers. For consideration, please submit your cur-riculum vitae to: The Institute for Medical Research,Human Resources Department 435, P,O Box 4000,Princeton, NJ 08543-4000. An Equal OpportunityEmployer.

SQU1BBWhere science comes to life.

POSTDOCTORALRESEARCH

FELLOWSHIPSMOLECULARBIOLOGY-MOLECULARIMMUNOLOGY

We are looking for Postdoctoral Research Fellowsto join Dr. Mario Geysen's group working in a newera of drug development through the wide andsystematic application of a unique peptide synthe-sis technology and concepts. Target areas covervirtually all therapeutic categories, e.g. hormoneanalogues, antiviral agents, vaccines, etc. A rele-vant PhD is essential with preference being givento candidates who have had one previous postdoc-toral position.

These positions offer the prospect of independentresearch and publication will be strongly encour-aged.

CSL is Australia's leading manufacturer of biologi-cals and has a strong commitment to Researchand Development. The unique work in molecularimmunology is conducted through Dr. Geysen'sgroup and has very significant levels of fundingand autonomy; the work is already being pro-gressed on many fronts and through importantinternational collaborative projects.

CSL's major facilities are located at Parkville whichis four kilometers from the centre of Melbourne,and is in close proximity to the University ofMelbourne, the Walter and Eliza Hall Institute ofMedical Research and several other institutions.

We offer competitive salaries and travel and asso-ciated benefits for these 2 year appointments.Appointees will commence with us during thesecond half of 1987.

Please send a cv outlining your qualifications,description of scientific experience and thenames of two referees, to Mr. E.D. Eade, Per-sonnel Director, Commonwealth Serum Labo-ratories, 45 Poplar Road, Parkville, Vic. 3052,Australia, by 15 May 1987.

COMMONWEALTHSERUMLABORATORIES

DIRECTOR, DIVISION OF SAFETYDepartment of Health and Human Services

Public Health ServiceNational Institutes of Health

Office of the Director, Division of SafetyThe National Institutes of Health is seeking applicants for the position of Director, Division ofSafety. The position provides direction to the occupational medicine, occupational safety andhealth, environmental protection, radiation safety, security and emergency management programof the National Institutes of Health. Interested individuals must possess a high degree oftechnical competence and a broad managerial background in order to provide nationalleadership in laboratory safety, occupational and environmental health risks associated withbiotechnology, disposal and treatment methodologies for hazardous research wastes, emergencypreparedness and protection from external threats.

Candidates must possess three years of general experience and three years of specializedexperience. At least one year of the specialized experience must have been at a level of difficultycomparable to that of the next lower grade in the Federal service. The general experiencerequirement may be substituted by a full four-year course of undergraduate study in anaccredited college or university. Credit will also be given to graduate education in appropriatefields. Specialized experience is professional experience in occupational safety and health,industrial hygiene, industrial engineering, health physics, environmental protection, safetyengineering or related scientific fields. In addition, candidates must possess: (1) expertknowledge of safety and occupational health, environmental health, emergency management andsecurity programs and issues relative to a biomedical research environment; and (2) skill inprogram management and evaluation processes.

Desirable qualifications include: (1) Ph.D. or equivalent degree in an appropriate field; (2)extensive background in public health, environmental health or institutional health and safetyprograms.

The position will be filled through the Civil Service or Commissioned Corps of the Public HealthService. The salary range is $53,830 to $69,976. Benefits include a retirement plan, health andlife insurance, sick and annual leave. Duty location is Bethesda, Maryland. Citizenship isrequired.

Applicants must submit a Personal Qualifications Statement-Standard Formr 171. To receiveconsideration applications must be postmarked by May 4, 1987.

For additional informatin you may cal: Ms. Nadgy P. Roey or Ms. Paricia Southcom on(301) 41-6521 or write to Natfonal Insftttes of Nimh, Oice of the Director, PersonnlOfice, 9000 Rockville Pike, BMI 31, Room 1C23, Betlesda, Maryland 21612.

An Equal Opportunity Emplorer

L

"The world expectsexcellence from Merck.

Link your future with ours!"ENZYMOLOGISTS

Merck Sharp and Dohme Research Laboratories has several excellent oppor-tunities available in the newly created department of Enzymology.

SENIOR RESEARCH BIOCHEMIST-Ph.D. in Biochemistry/Chemistrywith two or more years of post-doctoral experience in enzymology. This posi-tion will involve purification of enzymes from mammalian sources, enzymeinhibition and catalysis kinetics, and enzyme mechanistic studies. The suc-cessful candidate should have a strong record of achievement as evidencedby publication in refereed journals. Excellent oral and written communica-tion skills are essential.

STAFF BIOCHEMISTTemporary and permanent positions are availablefor candidates with a B.S./M.S. in biochemistry or chemistry with experiencein enzyme purification and a working knowledge of enzyme kinetics.Merck Sharp & Dohme Research Laboratories is located in Rahway, NewJersey approximately 20 miles south of New York City. Our salaries, benefits,and growth potential are excellent.Interested candidates should submit their curriculum vitae with a publi-cation list, salary requirements, and the names of three references to:Ms. Alaina L. Love, Merck & Co., Inc., P.O. Box 2000, R80M-TLI, Rahway,New Jersey 07065.

EQUAL OPPORTUNITY EMPLOYER

Correspondence will be kept strictly confidential.

ASSISTANTPROFESSORPHARMACOLOGY

THE PHILADELPHIA COLLEGE OFPHARMACY & SCIENCE invites appli-cations for a tenure-track position inPharmacology.

Candidates should have a PhD in Pharm-acology with experience in the area ofCardiovascular Pharmacology. Preferencewill be given to individual with Post-Doctoralexperience.

Candidates must be capable of mountinga vigorous research program in support ofour graduate programs in Pharmacologyand Toxicology.

In addition, they must participate in theteaching of undergraduate Pharmacy andToxicology students. The position is to befilled on or before August 15, 1987.

Applicants should submit curriculum vitaeand a list of references by May 1, 1987 to:

Mr. Gary L. Lage, PhD.Chairman, Department of

Pharmacology & Toxicology

PHILADELPHIACOllEGEOFPHARMACY & SCIENCE

Woodland Ave. at 43rd St.Philadelphia, PA 19104

EOE M/F/H/V

A highly qualified Toxicology Center in Rome

is seeking an

EXPERIENCED SCIENTIST

endowed with great organizing qualities to fill a challenging top management position.

The successful candidate will be responsible for organizing the activities of the Center and forpromoting its high scientific image. He will be assisted, whenever necessary, by internationallyrecognized experts.

An attractive salary-relative to qualification and experience-and cultural opportunities at thehighest level are offered.

Qualified candidates are kindly requested to submit their curriculum7vitae to:

A. MENARINI S.A.S.-Pharmaceutical Industries-Vla Sette Santi, 350131 Florence, Italy.

RESEARCH

INVESTIGATOR

G. D. Searle is a worldwide leader in thepharmaceutical industry. An outstandingopportunity exists for a qualified individual

in our Research and Development Division located inthe northern suburbs of Chicago.Primary responsibilities include investigation of platelet-receptor ligand interactions. A strong background inplatelet adhesion, activation, and aggregation, as wellas the biochemistry and/or pharmacology of the coagu-lation system is required. The qualified candidate willhave a Ph.D. and 1-3 years of experience with a goodpublication record in the field. The position has super-visory responsibility and requires strong interactionwith members of the team.Searle offers an excellent salary, high visibility, and goodupward mobility. Qualified candidates please forwardyour resume in strict confidence to David Wackrow-UF9, G. D. Searle, Research and Development A-1,4901 Searle Parkway, Skokie IL 60077. An EqualOpportunity Employer.

BIOCHEMISTSHercules Incorporated, a Fortune 500 Company involved in the develop-ment and production of chemicals, fibers, and plastics, has immediateopenings for 2 Biochemists at its main Research facility in suburbanWilmington, Delaware.The successful candidate will have a Ph.D. in Biochemistry, Biophysics,or a related area. Research activities will include the chemical and phy-sical modification of proteins particularly collagen or other structuralproteins. As principal investigator, responsibilities will include the gener-ation and execution of new ideas for the modification of materials forappropriate uses. Experience in biochemistry and biopolymers is essentialfor successful performance in this position.Hercules Incorporated offers a competitive salary in addition to a compre-hensive benefits package. Qualified applicants should forward a resumewith salary requirements to: James Jaquin, Supervisor, Human Resources.

Hercules IncorporatedHERCULES Research Center

____________________ Wilmington, DE 19894Equal Opportunity Employer

PharmacologistThe Procter &Gamble Company has an immediate entry levelopening for a Ph.D. pharmacologist or physiologist withresearch experience in neuropharmacology and electro-physiology. The position is in the analgesic research pro-gram at Miami Valley Laboratories in Cincinnati, Ohio. Theapplicant should have a Ph.D. in pharmacology or physi-ology with 0-2 years postdoctoral research experience.Requirements include a good understanding of the in vitrotechniques used to study the actions of neurotransmittersand novel drugs on neuronal function. Specific responsi-bilities will include studying the effects of novel analgesiccompounds on the peripheral and central nervous system.Besides offering a stimulating environment for professionalgrowth, the company provides a competitive employmentpackage including paid relocation, and Company-paidhealth, dental and profit sharing benefits.Candidates must be U.S. citizens or hold a permanentresident visa. Resumes with list of publications should besent to:

Dr. T. J. Logan, ManagerPh.D. RecruitingPharmacologist PositionThe Procter & Gamble CompanyMiami Valley LaboratoriesP.O. Box 39175Cincinnati, Ohio 45247

Procter & GambleAN EQUAL OPPORTUNIlY EMPLOYER No agency referrals

Idw- =1%11

GROUP LEADERENZYMOLOGY

The Pharmaceutical Research Division of Warner-Lamberthas an immediate opening for an outstanding Ph.D. in Enzy-mology to the position of Group Leader/Enzymology in our Bio-chemistry Section. The selected candidate will head a smallteam and will participate in a multidisciplinary environment,generating novel drug discovery strategies and evaluationtechniques for a variety of therapeutic categories.Qualified applicants will possess the following:* Ph.D. in Enzymology* A minimum of 5 years postdoctoral experience with astrong background in enzyme reaction mechanisms,techniques of enzyme purification and in vitro assay.Experience in the enzymology of arachidonic acidmetabolism would be considered an advantage.

* Excellence in research and oral communication skills areessential as are proven supervisory skills.

We offer excellent compensation and benefits at our modernfacilities adjacent to the University of Michigan campus. Quali-fied applicants should send curriculum vitae in confidence to:Ms. S. Hultquist, Human Resources Representative,Warner-LambertParke-Davis, 2800 Plymouth Rd., AbnArbor, Michigan 48105.

WA RA IELAMOERTEQUAL OPPORTUNITY IN ACTION

I S _A PhD level position in Microbiology isavailable at Du Pont's Experimental Station. As amicrobiologist, you will conduct independent researchprograms focusing on the molecular biology of grampositive bacteria and mechanisms of protein secretion inprokaryotes. To qualify, you should have post-doctoraltraining in microbial genetics, recombinant DNAtechnology and biochemistry, followed by experiencedirecting an independent research program.

You'll find a highly stimulating scientificenvironment in a modern research facility located nearWilmington, DE. We offer excellent compensation andbenefits including relocation. Our Mid-Atlantic locationoffers an attractive lifestyle with easy access to a widerange of academic, cultural and recreational activities. In-terested candidates should send their resumes with salaryrequirements and references to: S.T. Toy, Employee Rela-tions Department, Room X50734, Du Pont Company,Wilmington, DE 19898.

_________________ _U.S. Citizeniship or Pernanent VISA Required.UyAi Eqial Opportunity Employer M/F/H/V

S;X,.,.a S

E; IDEC IncorporatedU ~~~ ~ ~ ~ ~ ~~~---

IDEC Incorporated, a recently formed biotechnology companylocated in Mountain View and La Jolla, California is a leader inresearch involving immunoregulation with anti-idiotype antibodies.IDEC is currently conducting clinical trials at leading institutionswith its proprietary technology. IDEC currently has excellent careeropportunities for the following positions:

Research Director: Experienced research manager sought to leadcorporate research programs. Candidate must have a recent recordin the conception, execution, and management of innovativebiological research, preferably in a product oriented environment.Candidate must demonstrate the ability to contribute meaningfullyto the corporate research and development planning process, and tosuccessfully lead scientists in pioneering biological research.Suitable candidate should possess a Ph.D. and/or M.D. or equivalentdegree specializing in cellular biology and/or immunology withseveral years of managing experience.

Senior Scientists/Research Scientists: All levels of scientistswith experience in immunoregulation, anti-idiotype networkimmunobiology, and molecular immunology are sought. Successfulcandiates should have academic or industrial experience with theability to lead research programs. Suitable candidates must possessa Ph.D., and/or M.D. or equivalent degree.

Research Assistants: Candidates should have at least two yearsexperience in an immunology lab. Experience should includetechnical expertise in hybridoma antibody development, tissueculture, immunochemistry and related areas. Candidate must havea B.A./B.S. or M.S.

For prompt, fully confidential consideration, please send yourresume to Personnel Director, IDEC Incorporated, 291 NorthBernardo Ave., Mountain View, Ca. 94043.

An Equal Opportunity Employer.

FERROSAN RESEARCH DIVISIONCOPENHAGEN

The independent Division has during the last decade establishedseveral discovery drug research programmes based on novelneurobiological mechanisms with relation to most central nervousdiseases. The innovative organisation will continue the strongcommitment to research and development within neuropsycho-pharmacology.

Ferrosan Research Division is centrally located just outsideCopenhagen.

With the expansion of our research we need:

EXPERIENCED BEHAVIORALPHARMACOLOGIST

Applicants having at least 2 years experience in rodent behavior-al pharmacology e.g. models for memory, tolerance develop-ment, withdrawal or abuse potential will be preferred. Pleasedirect applications including full CV to:

Dr. Leif Helth JensenHead of Behavioral Pharmacology Dept.A/S FerrosanResearch Division5 SydmarkenDK-2860 SoeborgDenmark(Phone: (1) 69 21 11)

PRECLINICAL RESEARCHCorporate headquarters of the NutraSweet Company is expanding itsPreclinical Research staff The successful candidates will join a

dedicated project team involved in the design, development, andassessment of chemical and food additive research.

PHARMACOKINETICISTFIELD OF WORK AND DUTIES: Involved in metabolic assessment ofnew chemical candidates in support of new food additive petitions.Direct work in pharmacokinetics and development of bioanalyticalmethods is required. Expected to design and supervise studies relatedto absorption, distribution, metabolism, and excretion (ADME).REQUIREMENTS: PhD in pharmacology/biochemistry/organic chemistry.Four to Seven years post degree expenrence in a pharmaceuticalcompany, and solid interpersonal and oral/written communication skills.A strong background in isolation/identification of metabolites andexperience within vivo and in vitro methods used for ADME studies andfamiliarity with GLP's are a real plus.

NEUROTOXICOLOGISTFIELD OF WORK AND DUTIES: Involved in neurotoxicological/neuropharmacological assessment of new chemical candidates as wellas conduct of both applied and basic research designed to support newfood additive petitions. Interact with academic/industrial scientists;design study protocols, implement and monitor studies; review reports;monitor general toxicology studies as needed.REQUIREMENTS: PhD in toxicology/phormacology (neurotoxicologyemphasis) 3-5 years post degree experience with pharmaceuticalcompany. Solid interpersonal and oral/written communication skills, andfamiliarity with GLP's.For consideration, send resume including salary history in confidence to:The NutraSweet Company, Employment Supervisor, Box III1,Dept. PN, Skokie, Illinois, 60076 equai opportunity employer m/f/h

The NutraSweet Company

-S

The Central Nervous System Research Unit of The Upjohn Company isbuilding a group to develop strategies for the promotion of post-traumaticaxonal regeneration and the treatment of neurodegenerative diseases.The successful Research Associate candidate will have a BS or MS degreeplus at least one year of research experience in related neurobiologicaltechniques. A research background in neurotrophic factors, extracellularmatrix molecules, or neuronal development and response to injury isneeded. Desirable techniques include: microsurgical implantation of pros-thetic devices into experimental animals; immunohistochemical localiza-tion of neuronal markers in prepared specimens; and 2-D electrophoreticseparation of isotope-labeled proteins. The position will include responsi-bility for laboratory organization, staff supervision, independent projectsand preparation of research reports.Kalamazoo is a medium-sized Southwestern Michigan community withaccess to a rich mix of cultural, educational and recreational pursuitsincluding numerous lakes and a four-season climate. Upjohn offers theopportunity for career growth, a competitive salary commensurate withexperience, a comprehensive benefits program and relocationassistance.For confidential consideration, please call from outside of Michigan tollfree 1/80C!253-8600, ext. 3-6767, (inside Michigan call collect 616/323-6767) to request an employment application be sent to you immediately.Please refer to ad number 21099-A when calling.

6 . 0 6

An Equal Opportunity Employer M/F

L-

POSITIONS OPEN

PATHOLOGIST-Must qualify for a facultv ap-pointment at the rank ofAssistant to Associate Professorof Pathologv, Brown University. Requirements includecertification by the American Board of Pathologv(AP/CP), training in hematopathology, experience anddemonstrated capabilitv in anatomic and clinical patholo-gv, teaching, research, and administration. The MiriamHospital is an Equal EmploymentlAffirmative Action Em-ployer. Resumes should be sent by 1 June 1987 to: TheChairman ofthe Search Committee, Sumner I. Zacks,M.D., Pathologist-In-Chief, The Miriam Hospital,164 Summit Avenue, Providence, RI 02906.

Ph.D. IN MOLECULAR BIOLOGYPh.D. in Molecular Biology desired for position in an

Oncology Hospital-based research laboratorv, to initiateresearch program involving: growth factors, oncogenes,and gene rearrangements in both solid and hematologicmalignancies.

Individual with several vears of postdoctoral experi-ence as well as record of independent, original researchpreferred. Send curriculum vitae and reference letters to:

Larry Nathanson, M.D.Wmthrop-University Hospital

222 Station Plaza NorthRoom 300

Mineola, NY 11501

PHYSICS-Oakland University's Physics Depart-ment invites applications for a 1-year position as VISIT-ING FACULTY for fall 1987, the rank to be deter-mined by qualifications. Responsibilities include teach-ing two courses per semester and active participation inresearch. Minimum qualifications are a Ph.D. degree inphysics or a related field and a record of research.Preference will be given to theorists and to experimental-ists who can interact with existing programs althoughcandidates in any subfield of physics will be considered.Send curriculum vitae including a statement of researchinterests and the names of three references to: ProfessorB. K Berger, Physics Department, Oaldand Universi-ty, Rochester, MI 48063. Telephone: 313-370-3416.To be given full consideration, the application should bereceived by 15 May 1987. Oakland Univerity is anAffirmativeActionlEqual OpportunityEmployer and encour-ages applicationsfrom women and minorities.

Immediate opening for a PLANT SCIENTIST tosupport research and development activities related tothe Controlled Ecological Life Support System Pro-gram at Kennedy Space Center. Ph.D. with minimumof 3 years of experience in greenhouse or growth cham-ber work related to crop sciences or biomass productionrequired. Specific experience in crop management inclosed systems, knowledgeable in hydroponic plant sup-port, plant nutrition, plant pathology, plant physiologi-cal ecologv or other related areas is preferred. Work withinterdiscplinary team of engineers/scientists in operationand maintenance of a large closed plant growth chamberused in study of bioregenerative processes for foodproduction and recycling of water, oxygen, and carbondioxide. Equal Employment Opportunity. Submit curricu-lum vitae to: J. R. Puleo, The Bionetics Corporation,BIO-1, Kennedy Space Center, FL 32899, by 8 May1987.

POPULATION, BEHAVIORAL, OREVOLUTIONARY ECOLOGIST.

Indiana State University, Terre Haute, IN 47809.The Department of Life Sciences invites applications fora position as assistant professor (tenure track) beginningfall 1987. Applicants must possess a Ph.D. Applicantswith research interests in terrestrial studies of animals orplant-animal interactions and a strong background inecological and evolutionary theory are encouraged toapply All applicants must have a strong interest inteachig and research at the undergraduate and graduatelevels and in directing doctoral dissertations. Applicantmust be a U.S. citizen or a permanent resident. Applica-tions received after 10 May 1987 cannot be assured offull consideration.Send curriculum vitae and three letters of reference to:

Dr. WVilliam J. Brett, ChairpersonDepartment of Life SciencesIndiana State UniversityTerre Haute, IN 47809

An Equal OpportunitylAffirmative Action Employer.

POSITIONS OPEN

POSTDOCTORAL FELLOWHYPERTENSION/RENAL

Wyeth Laboratories has a postdoctoral position avail-able in the Hvpertension/Renal Section to study thehemodynamic and renal actions of atrial natriuretic factorand other novel antihypertensives in conscious and anes-thetized animals. Applicants must possess a doctorate inphysiology or pharmacology with a strong researchbackground in cardiovascular and/or renal function.

Position is located at our company headquarters insuburban Philadelphia, PA. Interested candidates areinvited to send curriculum vitae and three letters ofreference to: Manager ofRecruitment, Wyeth Labora-tories, P.O. Box 8299, Philadelphia, PA 19101. EqualOpportunity Employer, MIFIVIH.

POSTDOCTORAL POSITION available immedi-ately for BIOCHEMIST or BIOPHYSICIST. Projectinvolves use of UV laser to study the mechanism ofaction of an enzyme with antigrowth and antiviral func-tions. Prior experience in laser technology not required.Salary range: $19,000 to $26,000. Send curriculum vitaeand names of three references to: Dr. Robert Silverman,clo Civilian Personnel, Uniformed Services Universi-ty of the Health Sciences, 4301 Jones Bridge Road,Bethesda, MD 20814-4799.

POSTDOCTORAL POSITION available in theDepartment of Medicine, Harvard Medical School,for a recent Ph.D. to study the control of blood celldifferentiation. Current work focuses on the molecularbiology and biochemistry oferythropoietin and its mech-anism of action. Experience with molecular biologicaland/or protein biochemical techniques preferred. Sendcurriculum vitae, statement of research interests, andnames of three references to: Dr. Arthur Sytkowski,New England Deaconess Hospital, 185 PilgrimRoad, Boston, MA 02215.

POSTDOCTORAL POSITION-ReproductiveBiology Laboratory, Case Western Reserve Universi-ty. Laboratory focused upon receptor binding, proteinkinases and phosphorylation in placenta, and amnionwith correlation to hormone release. Also molecularbiology ofaromatase. Background in protein purificationand molecular biologv desirable. Salary: $18,000 peryear minimum. Bv 15 May 1987 send curriculum vitaeand references to: Dr. John J. Moore, Department ofPediatrics, Cleveland Metropolitan General Hospital,Cleveland, OH 44109.

POSTDOCTORAL POSITION available to studyDNA replication and cellular aging in yeast. Experiencein veast genetics and recombinant DNA techniques isdesirable. Send curriculum vitae, including bibliography,and have three letters of reference sent to: Dr. S. M.Jazwinski, Department of Biochemistry and Molecu-lar Biology, Louisiana State University Medical Cen-ter (LSUMC), 1901 Perdido Street, New Orleans,LA 70112. LSUMC is an Equal OpportunitylAffirmativeAction Employer.

POSTDOCTORAL POSITION available Septem-ber 1987 to a person interested in studying chloroplastevolution and the site of synthesis of various plastidproteins in algae using EM immunocytochemistry and insitu hvbridization. Experience in electron microscopy isdesirable. Send curriculum vitae and the names of threereferences to: Dr. Sarah P. Gibbs, Department ofBiology, McGill University, 1205 Dr. Penfield Ave-nue, Montrial, Quebec, Canada H3A lBl.

Full-time POSTDOCTORAL POSITION availableimmediately for biophysicist trained in cellular electro-physiology to study calcium action in single neurons.Annual salary rate $21,948 to $27,360 depending onexperience. The dependence of membrane currents andoftransmitter release upon intracellular calcium activitvwill be measured using photosensitive calcium chelators.Presynaptic calcium will be measured during synaptictransmission and after post-tetanic potentiation usingfluorescent or absorbance-indicating dyes. Send resume,reprints, and two names of references to: Dr. RobertZucker, Department of Physiology-Anatomy, Uni-versity of California, Berkeley, CA 94720. Applica-tions must be received by 8 May 1987. The Univerity ofCaliforzia is an Equal OpportunitylAffirmativeAction Em-ployer.

358

POSITIONS OPEN

POSTDOCTORAL POSITION available immedi-ately for 2 or 3 years, to study expression of erythrocyteprotein antigens and blood groups. Methodologies in-clude hybridoma and immunochemical techniques, pro-tein purification and sequencing, and cloning of erythro-cyte membrane proteins. Experience in molecular genet-ics preferred; knowledge of immunology and/or giyco-protein biochemistrv helpful. Spring 1987 graduatesacceptable. Send resume, summary of interests, andnames of three references to: Dr. M. Telen, Division ofHematology-Oncology, Box 3387, Duke UniversityMedical Center, Durham, NC 27710. Duke Universityis an Affirmative ActionlEqual Opportunity Employer.

POSTDOCTORAL POSITION available for 2 or 3years, from 1 July 1987 to study neuropeptide isolation,characterization, and receptor interaction in a well-equipped neuroendocrine laboratory. A strong back-ground in biochemistry with training in peptide purifica-tion techniques, RIA, and cell culture of advantage. Sendcurriculum vitae and names of three references to: IvorJackson, M.D., Director, Division of Endocrinology,Brown University/Rhode Island Hospital, 593 EddyStreet, Providence, RI 02902. An Equal Opportuni-ty/Affirmative Action Employer.

POSTDOCTORAL POSITION available immedi-ately to study molecular mechanisms of visual transduc-tion in vertebrate photoreceptors, using biochemnical andimmunological approaches. Background in protein puri-fication, hybridoma production desirable. Please sendcurriculum vitae, copies of reprints, and three letters ofrecommendation to: Dr. H. E. Hamm, Department ofPhysiology and Biophysics, University of Illinois Col-lege of Medicine at Chicago, Box 6998, Chicago, IL60680. The University ofIlnois is an Equal OpportunityAffirwmive Action Employer.

POSTDOCTORAL POSITIONIN BIOPHYSICS

A 2-year position to continue work on the noveltechnique ofdifferential polarization microscopy in theareas of (i) long-range organization ofmammalian chro-mosomes, (ii) linear and circular dichroism and birefrin-gence imaging studies in cytoskeleton is available.The candidate will need a Ph.D. degree in biology and

some training in optical biophysical chemistry and mi-croscopy. Preference will be given to the applicant whohas demonstrated ability in subeellular isolation tech-niques, specific staiiing methods (including immuno-fluorescence), and has a practical knowledge in comput-er instrument interfacing.

Please send curriculum vitae, a letter of intent, and oneletter of recommendation to: Professor Carlos Busta-mante, Chemistry Department, The University ofNew Mexico, Albuquerque, NM 87131.

POSTDOCTORAL POSITION IN PRIMATEREPRODUCTIVE ENDOCRINOLOGY availableimmediatelv to Ph.D. to study peptide and steroidproduction by fetoplacental unit during baboon preg-nancy. Background in reproductive endocrinology andU.S. citizenship essential. Send curriculum vitae to:Eugene D. Albrecht, Ph.D., Department of Obstet-rics and Gynecology, University of Maryland Schoolof Medicine, 655 West Baltimore Street, Baltimore,MD 21201.

POSTDOCTORAL POSITIONSResearch on ion channels and sensory transduction in

microbes. Projects include stretch-activated channels,chemotaxis, and osmotaxis in E. coli; ion-channel mutantsin yeast, cloning of mouse acetylcholine receptor genesinto yeast; calmodulin-defective channel mutants andother channel mutants in Paramecium. Interdisciplinarytraining environment: patch clamp, recombinant DNA,protein chemistry, and microbial manipulations.

Salary commensurate with NIH guidelines. Send cur-riculum vitae and three references to: Julius Adler(Dcpartment of Biochemistry), Ching Kung, or Mi-chael Culbertson (Laboratory ofMolecular Biology),University of Wisconsin, Madison, WI 53705.The University of Wisconsin is an Equal Opportunityl

Affirmative Action Employer. Applications from minorityand women candidates and other qualified persons areencouraged.

SCIENCE, VOL. 236

The Protein Biochemistry Department in Biopharmaceutical Research and Development at Smith Kline &French Laboratories is seeking outstanding scientists with expertise in protein isolation and characterization.A variety of positions in process improvement and scale-up development as well as research in proteincharacterization (structure and function) are available.

ASSOCIATE SENIOR (ref: PB 1)INVESTIGATORResponsible for isolation of proteins fromrecombinant and natural sources and fordeveloping procedures to producebiopharmaceuticals for clinical trials andcommercialization. Resp'onsibilities will includedeveloping new protein purification methodsamenable to large scale. The successful candidatewill have a Ph.D. in Biochemistry or BiochemicalEngineering and have at least two yearspostdoctoral experience in modemchromatographic techniques such as HPLC, ionexchange and affinity chromatography.

SENIOR SCIENTIST (ref: PB 2)Responsible for planning, scheduling andsupervising large scale protein purificationaccording to cGMP's in order to support clinicalsupply needs and the development of commercialprocesses. Additional responsibilities will involveaccumulating and analyzing laboratory andproduction data, collaboration with other scientiststo develop appropriate scale-up procedures and thedesign of automated scale-up purificationtechniques. The successful candidate should havean MA/MS degree in a biochemical science with atleast five years relevant experience or a BA/BSdegree with at least eight years relevantexperience in conducting experiments in largescale protein purification. Familiarity withregulatory guidelines, laboratory automation andpreparation of products for human use is highlydesirable.

ASSISTANT DIRECTOR (ref: PB 3)Seeking a candidate with at least 8-10 yearsexperience and strong record of scientificachievement in the field of hemostasis and/or

fibrinolysis. Must have distinct leadership skills andpotential to grow in this area. Will manage six toten scientists including Ph.D.'s and associates indiscovery of novel thrombolytics and developmentof drug targets for use in rational design/discoveryof pharmaceuticals. Strong skills in verbal andwritten communication needed. Prior experience indrug discovery and development is desirable butnot a must.

POSTDOCTORAL SCIENTIST (ref: PB 4)Responsibilities include developing new techniquesfor isolation and purification of recombinantproteins. The successful candidate will have aPh.D. in Chemistry or Biochemistry with thesiswork involving separation of proteins and othermacromolecules. Experience in HPLC ofbiopolymers, counter current chromatography orpreparative electrophoresis is preferred.

ASSOCIATE SCIENTISTS (ref: PB 5)Two openings exist for associate scientists(BS/MS) with degrees in'Biochemistry or inChemistry or Biology with relevant biochemicalexperience.

Position A will focus on the preparation of novelprotein separation media such as affinity sorbentsor new HPLC supports, and the use of thesematerials to develop new protein isolationprocedures. The successful candidate will havedemonstrated skills in organic synthesis andprotein isolation.Position B will be devoted to the isolation andpurification of natural and recombinant proteinsboth at bench and large scale and to thedevelopment of new high performancechromatographic procedures for purification ofrecombinant products. Strong candidates will haveproven skills in protein purification and familiaritywith HPLC and electrophoresis.

We offer an excellent compensation and benefits package and an attractive relocation policy as well as awork environment that offers considerable opportunity for personal and professional growth. For confidentialconsideration, send your C.V. and names of three references, citing the appropriate reference number listedabove to Robert F. Obst, R&D Senior Employment Administrator, SmithKline Beckman Corporation, 1576Spring Garden Street, Philadelphia, PA 19101. We are an Equal Opportunity Employer, M/F/H/V.

POSITIONS OPEN

POSTDOCTORALPOSITION/BIOPSYCHOLOGY

Available imnmediately at Brooks Air Force Base, SanAntonio, TX. Studies of the effects of psychopharma-cological and nutritional intcrventions on human per-formance and physiology will be conducted. Experiencein psychopharmacology (especially human), electrophys-iology, and use of laboratory computers desirable. Appli-cation cutoff date: 30 May 1987. Send resume to:Administrator, Clinical Research Center E17445,Massadusetts Institute of Technology, Cambridge,MA 02319.

POSTDOCTORAL POSITIONS IN MOLECU-LAR NEUROBIOLOGY are immediately available tostudy the regulation, expression, and structure of specificgenes in the central nervous system. These genes includethe amyloid gene of Alzheimer's disease (Dr. C. G.Rasool), genes involved in neuro-immune function likeInterleukin-1 (Dr. M. P. Vitek), and various receptorgenes (staff). A background in molecular biology orbiochemistry is preferred. Please send curriculum vitaeand names of three references to: Dr. A. J. Blume,Molecular Neurobiology, CNS Biology, c/o Ms. Mau-reen Quigley, Professional Employment Repre-sentative, Lederle Laboratories, Pearl River, NY10965. Equal Opportunity Employer.

POSTDOCTORAIJRESEARCH ASSOCIATEPosition available for biochemical/biophysical studies

of membrane structure and lipid-protein interactions.Opportunities to combine biochemical studies of mem-brane lipids and membrane receptor-ligand interactionswith biophysical methods (calorimetry, x-ray/neutrondeffraction, electron microscopy, NMR).A doctorate in biochemistry, biophysics, chemistry, or

related area is required. Please send curriculum vitae, listof publications, and names of three references to: Dr. G.Graham Shipley, Bio-physics Institute, Boston Uni-versity School of Medicine, 80 East Concord Steet,Boston, MA 02118. Boston Univerity is anAffinativeActionlEqual Opportunity Employer.

POSITIONS OPEN

POSTDOCTORAL RESEARCH ASSOCIATEto study structure, molecular genetics, and endocrineregulation of glutathione transferases. Knowledge ofrecombinant technology and molecular endocrinologyand spectroscopic theory reuired. Salary: $26,000.

Please send rLsume to:irving Listowsky, Ph.D.,Department of Biochemistry, Albrt Einstein Collecgof Medicine, 1300 Morris Park Avenue, Bronx, NY10461. An Equal Opportunity Employer.

POSTDOCTORAL OR RESEARCH ASSO-CIATE position available immediately to study bio-chemical basis for antiviral activity of novel nucleosideanalogs. Experience in enzymology, nucleic acid bio-chemistry, and cell culture is desirable. Send resurn andthree letters of reference to: Dr. W. Prusoff, Depart-ment of Pharmacology, Yalc University School ofMedicine, New Haven, CT 06510.AnEqual Opportun-ity/lAffiatie Action Employer.

POSTDOCTORAL RESEARCH ASSOCIATE.Positions are now available to join a multidisciplinarygroup studying the structure and regulation of the genesor the catecholamine neurotransmitter biosynthetic en-zymes. Applicants should have a strong background ineither recombinant DNA technology or neurochemis-try/neuropharmacology. Send curnculum vitae, state-ment of research interest, and the names of three refer-ences to: Dr. Barry B. Kaplan, Molecular Neurobiolo-gy Program, Wester Psychiatric Institute and Clinic,University of Pittsburgh School of Medicine, Pitts-bug,PA 15213.

POSTDOCTORAL OR RESEARCHPOSMIION AVAILABLE IN MOLECULAR-

CELLULAR IMMUNOLOGYFOR Ph.D. OR M.D.

Studies deal with human lymphokine regulation andcell and gene doning as part of a major program on theinduction of transplant tolerance. Salary range from$24,000 to $34,000, depending on pnor expenence.Send curriculum vitae together with names of three

references to: Marvin R. Garovoy, M.D., Director,Immunogenetics and Transplantation Laboratory,HSE-520, University of Cafrnia, San Francisco,Third and Parnassus Avenues, San Francisco, CA94143.

The Univemity of Calonmia iv an Equal OpportunitylAffirmative Action Employer. Women and minorities areencouraged to apply.

POSTDIOCTORAL RESEARCH ASSOCIATES

Positions for NCI postdoctoral training program inmolecular and cellular mechanisms of carcmogenesis areavailable at The University of Texas System CancerCenter (UTSCC)-Scicnce Park Research programsfocus on the following areas: somatic cell genetics, DNArepair and mutagenesis, carcinogen metabolism and ad-duct formation, rumor promotion, mechanisms of lym-

phomagenesis, normal and tumor cell differentiation,biochemical genetics, growth factors. Current approach-es in whole animal and in vitro culture systems include:flow cytometry (BD FACS 440), HPLC, monoclonalantibody production, Southern blot analysis and DNAsequencing, isoenzyme analyses and electron microscopy.Applicants must be U.S. citizens or permanent residentsand have a Ph.D., M.D., or D.V.M. degree. For applica-tion forms contact: Dr. Thomas J. Slaga, Director,UTSCC, Scicnce Park-Research Division, P.O. Box389, Smithville, TX 78957. Tdelphone: 512-237-2403.An Equal OpportunitylAffirmatn'eAction Employer.

DEPARTMENT OF DERMATOLOGYPOSTGRADUATE RESEARCH BIOCHEMIST

Ph.D., experience in cell biology and biochemistry.Incumbent will investigate the binding and processing ofthe angiotensins substance P and erythropoietin by endo-thelial cells and the induced cellular events/gene activa-tion. Salary: negotiable.Submit a letter of interest, curriculum vitae, and the

names offive references to: Dr. Tania L. Weiss, Derma-tology Department-190, University of CaliforniaSan Francsco, VA Medical School, 4150 ClementStreet, San Francisco, CA 94121. Filing deadline:open until filled.

The University ofCalifornia, San Francivco, is an Affir-mativeActionlEqual Opportunity Employer.

POSITIONS OPEN

RESEARCH ASSISTANT for hospital located innortheastern Ohio to conduct research, compile data andstudy reports on newborn babies being breast-fed; com-pile data pertinent to response of immature kidney tovariabk sodium and calorie load presented by breast milkin first few days of life. Requires M.D. (or equivalentdegree/credentials determined to be equivalent to re-quired U.S. degree by an approved credentials evaluationagency) or Ph.D. in physiology, and 6 months ofexperence in the job described or 6 months internship inpediatrics specializing in malnourished babies. Fortyhours per week, $22,000 per year. Qualified applicantsreply immediately with resume to: R. Lechler, JO#3032783, Ohio Bureau of Employment Services,P.O. Box 1618, Columbus, OH 43216.

RESEARCH ASSISTANT PROFESSORModern, well-equipped department of oral biology

seeks individual with experience in molecular biology.Research interests should complement those of activedepartrnental members including characterization of sali-vary glycoproteins and bacterial surface antigens. Partici-pation in pre- and postdoctoral teaching is desirable.Send r6sumi and three letters ofreference by 1 May 1987to: Chairman, Oral Biology, 3435 Main Street, Fos-ter Hall, SUNY at B No,NY 14214. An EqualOpportunity Employer MIF.

RESEARCH ASSOCIATE with Ph.D. in electricalengineering or biophysics needed to participate in devel-opment and operation of a human motor physiologylaboratory studying basic mechanisms underlymg controlof voluntary movement and motor disability caused byneurological disease. Physiological, electronics and com-puter programming experience required. Write to: Tim-othy A. Pedley, M.D., Chairman, Committee onAppointments and Promotions, Department ofNeu-ro ogy, College of Physicians and Surgeons, 710West 168 Street, New York, NY 10032. ColumbiaUniversity is an Equal OpportunitylAffirmativeAction Em-ployer.

RESEARCH ASSOCIATE-Position available tostudy T-cell immune regulation in multiple sclerosis.Background T-cell fractionation, cloning, and lympho-kine research preferred. Anplicants should send curricu-lum vitae and names of &ree references to: Jeffrey I.Groenstein, M.D., Department ofNeurology, TempleUniversity School ofMedicne, 3400 North BroadStreet, Philadelphia, PA 19140.

Equal Opportunity Employer.

RESEARCH ASSOCIATES: Two positions tostudy regulation of key enzymes involved in carbohy-drate energy metabolism in complex biological systems,e.g. hepatocytes, synaptosomes etc. Ph.D. or M.D. re-quired. Previous experience in enzymology/biocnerge-tics, and/or ion fluxes desirable. Submit curriculum vitaeand have three letters of recommendation sent to: Dr.Tarun B. Patel, Department of Pharmacology, Uni-versity of Tennessee, Memphis, The Center forHealth Sciences, 874 Union Avenue, 100 CroweBuilding, Memphis, TN 38163.

RESEARCH ASSOCIATE, EXPERIMENTALHIGH ENERGY PHYSICS: Design, build, and installequipment for experimentation on Small Angle Proton-Antiproton Elastic Scattering at Fermilab Collider. Willbe senior physicist in charge of the construction of driftchamber telescopes for the experiment. Record data fromthe experiment using a PDP-11 computer. Analyze thedata using super-mini and mainframe computers. Writeand publish results. (Will spend about 6 months per yearat Fermilab and 6 months per year at NorthwesternUniversity.) Requires Ph.D. degree in experimental highenergy physics. Also requires 1 year experience in the jobto be performed or 1 year experience as a researchassistant, experimental high energy physics. Experienceto include data acquisition systems for high physicsexperiments, construction and operation of drift cham-bers, and the use of super-mini and mainframe comput-ers. Experience can be during academic training. Hours:9:00 a.m. to 5:00 p.m., 40 hours per week at $24,000per year salary. This is a university position. Please sendresume to: Ilfinois Departmcnt of plo ent Secur-

ity, 401 South State Street, 3 South h Illinois60605, Attention: Robert S. Felton, Reference #V-IL 6908 F. An employer-paid ad.

SCIENCE, VOL. 236

FACULTY POSITIONS IN NEUROBIOLOGYNEUROBIOLOGY RESEARCH CENTER

UNIVERSITY OF ALABAMA AT BIRMINGHAMMEDICAL SCHOOL

The University of Alabama at Birmingham hasrecently established a new Neurobiology ResearchCenter. Several tenure-track faculty positions areavailable beginning September 1988 to be filled atany level (Assistant, Associate or Full Professor).Faculty will hold appointments in basic sciencedepartments (Physiology and Biophysics, CellBiology and Anatomy, etc.) but be housed togetherin the Neurobiology Research Center. Faculty willstrengthen existing research programs in integra-tive and cellular Neurobiology and extend theUniversity's excellence in cellular and molecularbiology to the Neurosciences. Excellent facilities,start-up funds and ongoing support are available.

Applicants in all areas of Neurobiology areencouraged to apply. Initial recruiting will placeemphasis on integrative sensorimotor neurophysiol-ogy with attention to modeling, synaptic biophy-sics and molecular neurobiology of plasticity. Can-didates should hold the Ph.D. or M.D. degree andhave a minimum of 2 years postdoctoral experi-ence. Successful candidates will be expected tomaintain strong extramurally funded research pro-grams. Teaching responsibilities are minimal.

Please send a curriculum vitae, statement of futureresearch plans and names of 4 references to:

Dr. Michael FriedlanderDirector, Neurobiology Research Center

Volker HallUniversity of Alabama at BirminghamBirmingham, Alabama 35294 U.S.A.

UAB is an equal opportunity/affirmative actionemployer.

360

Port MoresbyVACANCY

Applications are invited from suitablyqualified persons for the following position:

LECTURER/SENIOR LECTURERIN BIOCHEMISTRY

Basic Medical SciencesRef. No: W821004/87

The above position will become vacant inJune 1987, in the Department of Basic Medi-cal Sciences in the Faculty of Medicine. ThisDepartment undertakes the pre-clinical train-ing of medical and dental students in Bio-chemistry, Anatomy, Pharmacologyand Phys-iology, and is responsible for post-graduatecourses in basic medical sciences. Departmen-tal and interdepartmental research isencouraged. The successful applicantwill havehad experience in teaching biochemistry tomedical students; it is the aim of this Depart-mentto present the pre-clinical medical sub-jects in a functional and clinically relevantcontext. Teaching/research experience in ade-veloping country would bean advantage.

SALARIESSeniorLecturer -K22,015, pa plus 24% gratuityLecturer 2 - K20, 165, pa plus 24% gratuityLecturer 1 - K18,315, pa plus 24% gratuity

Applications will betreated as strictly confi-dential and should includethree copies of a fullcurriculum vitae, a recent small photograph,the names and add resses ofthree referees anddate of availability. In orderto expeditthe ap-pointment procedure, applicants are advisedto contact their referees to send confidentialreports directly to the University without wait-ingto be contacted. Applications should befor-warded to the Deputy Registrar (Staffing),University of Papua New Guinea, P.O. Box320, University Post Office, Papua NewGuinea.

Applications close 30 April 1987

F P DIALA (MR)REGISTRAR.

HRA 8785

POSTDOCTORALRESEARCH

OPPORTUNITIESAT CSL AUSTRALIA

We are looking for MOLECULAR BIOLOGISTSand MOLECULAR IMMUNOLOGISTS to join Dr.Mario Geysen's group working in a new era of drugdevelopment through the wide and systematicapplication of a unique peptide synthesis technolo-gy and concepts. Target areas cover virtually alltherapeutic categories, e.g. hormone analogues,antiviral agents, vaccines, etc. Postdoctoral expe-rience in an appropriate laboratory of high reputa-tion, demonstrated ability to be innovative and thecapacity to run a research project are essential.

These positions offer the prospect of independentresearch and publication will be strongly encour-aged.

CSL is Australia's leading manufacturer of biologi-cals and has a strong commitment to Researchand Development. The unique work in molecularimmunology is conducted through Dr. Geysen'sgroup and has very significant levels of fundingand autonomy; the work is already being pro-gressed on many fronts and several importantinternational collaborative projects have been es-tablished.

CSL's major facilities are located at Parkville whichis four kilometers from the centre of Melbourne,and is in close proximity to the University ofMelbourne, the Walter and Eliza Hall Institute ofMedical Research and several other institutions.

We offer competitive salaries, removal expensesand associate benefits for these appointments.Appointees will commence with us during thesecond half of 1987. The terms of the appoint-ments are flexible in that we are prepared toequally consider those interested in a minimum of2 year appointment or a longer term career oppor-tunity.

Please send a cv outlining your qual-iications,description of scientific experienc,e and thenames of two referees, to Mr. E.D. Eade, Per-sonnel Director, Commonwealth Serum Labo-ratories, 45 Poplar Road, Parkville, Vic. 3052,Australia, by 15 May 1987.

EEL COMMONWEALTHSERUMLABORATORIES

POSITIONS OPEN

Applcations are invitcd for the position of RE-SEARCH ASSISTANT PROFESSOR in the Dcpart-ment of Biochemistrv from individuals with at least 2vears of postdoctoral experience in the biochemistry ofblood coagulation. Qualified applicants with a provenability to obtain extramural fundng must possess exten-sive experience in the following areas: Purification ofproteins associated with blood coagulation includingfactor V; characterization of blood clotting proteinsutilizing synthetic phospholipid vesicles; development ofmonoclonal antibodies; enzvmologv, including steadv-state and rapid-reaction kirietics, hvsteretic transients,steady-state transient analysis and the use of active-sitedirected inhibitors; fluorescence techniques indudingstopped-flow, fluorescence polarization and the use offluorescent probes to define macromolecular complexassemblies. Salarv $30,000 per vear; 40 hours per week.Respond to: Robert Mattson, Supervisor Job Service,Department of Employment and Training, P.O. Box488, Montpelier, VT 05602.

RESEARCH ASSOCIATE to devise and carrv outthe svnthesis of biologicallv active peptides like comple-ment component C-3 and C-5a, human interferon andmouse cysteine proteinase and other unnatural proteinslike betabellins, introducing active and binding sites tomimic the natural enzymes. Ph.D. in organic chemistrvwith 1 year of experience in peptide chemistry, to includeworking knowledge of the synthesis of peptides andproteins and experience using HPLC, NMR, and TLC.Salary $22,000. Contact: The Job Service at 317 Cald-well Street Extended, Chapel Hill, NC 27514, or theJob Service Office nearest you. Refer to Job Order #NC 6103932.

RESEARCH PROGRAM CHIEFALFRED I. duPONT INSTITUTE OF THE

NEMOURS FOUNDATIONThe Alfred I. duPont Institute is a growing children's

hospital dedicated to multispeciality patient care, re-search, and education. The Institute plans to implement anew research and development program concerned withthe application of digital electronic and computer tech-nology to the needs of our handicapped patient popula-tion. We are seeking a senior-level scientist-engmeer toprovide leadership for this program. This individualshould possess an advanced degree(s) in electrical engi-neering, computer science or biophysics, and demon-strated experience in the application of these fields toadaptive human physiology for handicapped individuals.

Interested applicants please forward curriculum vitaeand names of three references to: Charles R. Hartzell,Ph.D., Director of Research, The Alfred I. duPontInstitute of the Nemours Foundation, P.O. Box 269,Wimington, DE 19899. Equal Opportunity Emplayer.

RESEARCH STAFF MEMBER: Performs inde-pendent research on polymeric materials for o ticalrecording and optical device applications. Research in-dudes: lucidation of molecular structure-mechanical,thermal, optical property relationships, induding designand development of measurement methodologies, dataanalysis and modeling; building of prototype opticaldevices (recording discs, optical elments, patterned sub-strates) and testing of performance lifetime characteris-tics; building of electrical/semiconductor test devices forevaluating polymer properties and optical prototypeperformance characteristics; requires Ph.D. or equivalentin applied physics with emphasis on polymeric materials(ifno Ph.D., then strong record of independent researchrequired); 2 years of research experience with optical andclectrical properties of polymer; strong background inpolymer structure-property relationships [requires expe-nence with thermal analytical techniques, mechanicalanalytical techniques, dielectric techniques, x-ray (smalland wide angle), IR spectroscopy]; experience withprocessing of polymer materials including blending ofpolymers, extrusion of films and modeling of polymers;working knowledge of solid-state devices including met-al-polymer-semiconductor test structures, piezo-andpyroclectric polymers, liquid crystalline polymers, opticaldevices; demonstrated ability to carry out independentresearch and publish results. Forty hours per week;$52,000 per year. Job and interview site: San Jose, CA.Send this ad and resume to: Job #MA2771, P.O. Box9560, Sacramento, CA 95823-0560, not later than 2May 1987. Equal Opportunity Employer.

RESEARCH ASSOCIATESIMMUNOLOGY/PROTEIN BIOCHEMISTRY

AND MOLECULAR BIOLOGYROSWELL PARK MEMORIAL INSTITUTESeveral positions for research associates with 2 years of

postdoctoral experience are available to study the mecha-nisms of immune system regulation by biological re-sponse modifiers. Projects within the group are flexible,ranging from isotype-switch regulation in the IgA systemto activation of gene expressson bv lymphokines andhemopoietic growth/differentiation factors. Salary will becommensurate with background and experience. Pleasesend curriculum vitae, statement of research interests,and names of three references to:

Thomas B. Tomasi, M.D., Ph.D.Director, Roswell Park Memorial Institute

Chairman, Department of Molecular Medicineand Immunoloy

Roswell Park Memorial Institute666 Elm Street

Buffalo, NY 14263Roswell Park is an AffirmativeActionlEqual Opportunity

Emplyer.

SENIOR RESEARCH PHYSICIST. Perform fun-damental and applied research on the preparation ofphysical, electricaL, and optical properties of amorphoussemiconductors; constructing integrated circuit evicesand identifving aspects which lead to business opportuni-ties; lead work in Amorphous Semiconductor Group ofthe Phvsical Technology Division of Corporate Researchat firm's Research Center. Ph.D. in physics required with3 vears of experience in the job offered or 3 years ofexperience as Chief Physicist and/or Group Leader,Amorphous Semiconductors and Optoelectronic Pro-gram. Experience as ChiefPhysicist and/or Group Leaderrequires investigation of thin-film amorphous semicon-ductors and developing optoclectronic devices and otherIII/V compound semiconductor devices. Forty hours perweek, M/F, 8:30 a.m. to 5:00 p.m., $67,000 per year.Send resume and Social Security Number to: IllinoisJob Servicc, 401 South State, 3 South, Chicago, IL60605, Attn: Mr. L. Boksa, Reference #6683. Anemployer-paid ad.

RESEARCH BIOLOGIST VA Medical Center, St.Louis, Missouri requires professional background inmicrobiology, biochemistry and veterinary medicine andexperinece i purification techniques and eukaryoteDNA cloning. Salary: $27,172 per annum. To applycontact: Ms. Blair, (05-JB) VA Medical Center, St.Louis, MO 63125. Telephone: 314-894-4676. EqualOpportunity Employer.

KEUKA COLLEGEKEUKA PARK, NEW YORK

Entry-level, TENURE-TRACK position to teach KI-NESIOLOGY and NEUROANATOMY/PHYSIOL-OGY to occupational therapy majors, and to carry someresponsibility or anatomy and physiology and/or compara-tive animal physiology. Keuka College is a independentcoeducation college located in the Finger Lakes region ofupstate New York. Applications consisting of curriculumvitae, three letters of reference, and transcripts should besubmitted by 15 May 1987 to: Dr. J. E. White, ChimDivision Of Natr Sdencs, Kuka Park, NY 14478.

TWO POSTDOCTORAL POSIIONSMOLECULAR BIOLOGY OFHUMAN LEUKOCYTESBETH ISRAEL HOSPITAL

HARVARD MEDICAL SCHOOLAvailable immediately for Ph.D.'s in molecular biolo-

gy, preferably with experience in gene doing andsequencing. One position to study human granunocyte/monocyte differentiation through the cloning of andanalysis of genecxpression of mycloid specific antigens.The second position, with long-term grant support, isavailable for a new Ph.D. or more senior researchassociate to work on gene cloning, regulation of expres-sion, structure and function of major proteins of humancosinophilic and basophilic leukocytes. Send curriculumvitae and three ktters of reference to: Dr. Steven J.Ackerman or Dr. Daniel G. Tenen, Department ofMedicine, Beth Israel Hospital, 330 Brookline Ave-nuc, Boston, MA 02215.

DEPARTMENT OF PATHOLOGYUNIVERSITY OF ARIZONACOLLEGE OF MEDICINE

Applications are solicited for a TENURE-TRACKFACUJLTY POSITION in anatomical pathology, witha major commitment to neuropathology and neuro-muscular disorders. Minimum requirements are: medicaldegree, certification by the American Board of Pathologyin anatomical pathology (anatomical and clinical pathol-ogy certification desirable), and neuropathology. At least5 years of experience in neuropathology, and the abilityto sustain an investigative and research program incuropathology with past experience in the developmentof a research program. The position will require teachingexperience at graduate and postgraduate level with medi-cal student and house officer contact. Applicants shouldsend curriculum vitae to: Jack M. Layton, M.D., Head,Department ofPathology, University ofArizona Col-lege ofMedicine, Tucson, AZ 85724.An Equal Oppor-unityAffirmativeAction/Tite 1/XSecton 504 Employer.

SUMMER INSTITUTE

FIFT-H SUMMER INSTITUTEIN RISK MANAGEMENT IN

ENVIRONMENTAL HEALTH ANDPROTECTION

16 to 19 June 1987. Legal, financial, and decision-making aspects of risk management; risk perception, riskcommunication; quantitative risk assessment. Emphasisupon hazardous and toxic waste problems. Bachelor'sdegree or equivalent required. Write: Summer Institutein Risk Management/Graduate School of Public Ad-

nNew York University, 4 WashingtonSquare North, New York, NY 10003; or telephoneProfessor Zimmerman at: 212-598-3725.

SYMPOSIUM

SYMPOSIUM: Swaimonine and relaed glycosidaseinhibitors, 10 to 14 August 1987, at Utah State Univer-sity, Logan, Utah. Topics include comparison ofinducedand genetic glycoprotein storage disease; effects of glyco-sidase inhibitors (e.g., swainsonine, 1-deoxynojeremy-cin) on glycoprotein and carbohydrate processing; chem-istry and biology of glycosidase inhibitors (synthesis;toxicology; sources). Oral presentations or posters wel-come. Contact: L. F. James, Poison Plant ResearchLaboratory, 1150 East 1400 North, Logan, UT84321; telephone: 801-752-2941, or C. D. Warren617-726-3748; R. J. Molyneux 415-486-3557; AlanElbein 512-567-3750.Title deadline: 1 June 1987

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIP IN DEVEL-OPMENTAL RESPIRATORY CONTROL IN RE-LATION TO NEUROMODULATORS. The suc-cessful applicant (M.D./Ph.D.) will have experience withnerve/CKS recordings, microiontophoresis. Plese sendletter, resume, and three references to: I. R. Moss,M.D., Ph.D., Director, Pediatric Pulmonary Divi-sion, The University of Texas Health Science Ccnterat Dallas, 5323 Harry Hines Boulevard, Dallas, TX75235-9063. An Equal Opportunity Employer.

MARKETPLACE

SCIENCE, VOL. 236362

POSITIONS OPEN POSITIONS OPEN

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You'll only need __L15 minutes to learn .ENhow Gilson HPLCsystems put you intotal control with minimum effort.Our new 714 HPLC System Controllersoftware runs on an IBM PC ATTM,using MS DOSTm and MicrosoftWindows.m This windows formatgives you fast, easy access to allparameters for method develop-ment and data analysis.The 714 controls up to four Gilsonpumps, in addition to major periph-

erals like our 231/401 Auto-Injectorand 1 16 UV Detector. And it doesn'tstop there. Other application pro-grams, like word processing and.graphics, are supplied with our soft-ware, so you can use your computerfor everything it was built to do.

Data analysis that's sophis-ticated, yet simpleOur data analysis func-tions offer the sophis-tication you need witha simplicity you'll enjoy.Save, analyze and plot

- up to four channels,applying different pa-

rameters to each channel foroptimal analysis.- Get real-time, on-screen chromatography display inaddition to hard copy printouts ofall methods, plots and reports.

Gilson systems.Built to grow. Built to lastOur systems are modular,"so youcan combine-components to bestsuit your needs-from microbore toprep, at up to 100 ml/min. As yourneeds change, you can easily addcomponents to meet those needs.And every Gilson system is built tokeep on running, day after day. Soit stays on your lab bench. Not ona Workbench.

We've done everyt g wecan to simnplify HPLC. .the rest is up to you.For immediate response, call toll-free

Re-analyze one or a hundred files 800-445-7667 for your free demoall automatically. The high-capacity diskette. Or, circle the reader serv-memory is ice numbers below for moreideal for the information.

IBM PC AT Is a regstered trademark of IrnternationalBusress Machaens Corporation.MS DOS and Windows are registered trademarks of Macrosoft Corporation.

© 1987 Gilson Mecical Electronics, Inc.~GILSON

INTERNATIONAL

GILSON MEDICAL ELECTRONICS, INC., BOX 27, 3000 W. BELTLINE HWY., MIDDLETON, WI 53562 USA, TEL.: (608) 836-1551 TELEX: 26-5478IN EUROPE: GILSON MEDICAL ELECTRONICS (FRANCE) S.A., 72 RUE GAMBETTA, B.P. NO. 45,95400, VILLIERS-LE-BEL, FRANCE, TEL.: (1) 39.90.54.41 TELEX: 696682

For literature circle reader service number 233To have a representative call circle reader service number 234