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Polymer Chameleons: Emerging Trends and Polymer Chameleons: Emerging Trends and Opportunities Opportunities Assessing polymers that are designed to act as an 'on-off' switch based on a particular stimulus Aarthi Janakiraman, Industry Analyst © 2013 Frost & Sullivan. All rights reserved. This document contains highly confidential information and is the sole property of Frost & Sullivan. No part of it may be circulated, quoted, copied or otherwise reproduced without the written approval of Frost & Sullivan. Aarthi Janakiraman, Industry Analyst Chemicals and Materials, Technical Insights October 1, 2013
Transcript

Polymer Chameleons: Emerging Trends and Polymer Chameleons: Emerging Trends and OpportunitiesOpportunities

Assessing polymers that are designed to act as an 'on-off' switch based on a particular stimulus

Aarthi Janakiraman, Industry Analyst

© 2013 Frost & Sullivan. All rights reserved. This document contains highly confidential information and is the sole property of

Frost & Sullivan. No part of it may be circulated, quoted, copied or otherwise reproduced without the written approval of Frost & Sullivan.

Aarthi Janakiraman, Industry Analyst

Chemicals and Materials, Technical Insights

October 1, 2013

Today’s Presenter

Functional Expertise

� Expertise covering broad range of sectors including:

• Materials & Coatings• Polymers and Biomaterials• Food & Beverages• Health and Nutritional Supplements • Dietetics and Healthcare

Industry Expertise

Experience base covering broad range of sectors, leveraging long-standing working Aarthi Janakiraman

2

� Experience base covering broad range of sectors, leveraging long-standing working relationships with leading industry participants’ Senior Executives in

• Chemicals and Materials• Coatings• Food and Beverages• Healthcare and Wellness

Education

� Post Graduate Program in Business Administration from Indo-German Training Centre, awarded by German Commerce of Industry & Trade, Germany

� Master of Philosophy from Avinashilingam Institute of Higher Education for Women, Coimbatore, India.

Industry Analyst Technical Insights –Chemicals, Materials and Foods

Frost & SullivanGlobalChennai, India

Agenda

Today’s presentation will cover:

� A Brief Snapshot

� Application Landscape

� Drivers & Challenges and their Impact

3

� Key Developments

� Insights – The Road Ahead

� Conclusions

Technology Snapshot

Sneak Sneak Sneak Sneak

Definition:• “Polymer Chameleons’ are stimuli-responsive polymers, also known as “smart” polymers or

“environmentally sensitive” polymers that undergo rapid changes in their microstructure, triggered by changes in the environment.

• External stimuli, including heat, pH, ionic strength, magnetic and electric fields, light, ultrasound, andchemical species.

• Changes are reversible; and the system is capable of returning to its initial state on trigger removal

Why Is It Important?• Ability to change the wettability, permeability, as well as adhesive, adsorptive, mechanical,

and optical properties of the product.

• Ability to adjust in a predictive manner to a certain stimulus or condition is essential for the

4

Sneak Sneak

PreviewPreview

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PreviewPreview

• Ability to adjust in a predictive manner to a certain stimulus or condition is essential for thedevelopment of targeted delivery techniques and other biomedical applications.

Key Advantages:• Can regain their original shape/characteristics after the stimulus is removed.• Could be fine tuned for obtaining a desired characteristics of the end product.• Can respond to one or more triggers.

Some Examples:• Synthetic polymers such as poly(N-isopropylacrylamide) or PNIPAM, para-Methoxy-N-

methylamphetamine or PMMA, poly(methyl acrylate) or PMA.• Bio-polymers such as Proteins (elastin, collagen), Protein analogs, Protein-based polymers, and

Self-assembling peptides.• Hybrid systems such as Polyethylene glycol (PEG) and bio-reinforced polymers.

Application Landscape—Different Industry Segments

Self-healing surfaces

Types of Reactions

pHpH

Temperature

Temperature

LightLight

Ultra-SoundUltra-Sound

Industry Segments

Drug Delivery

Wound Dressing

Medical stents

Bio-separationApplication

Areas

HealthcareHealthcare

AutomotiveAutomotive

SensorsSensors

Chemical Chemical

Types of Triggers

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Self-Directed Electronic Control System

EnzymeEnzyme

Magnetic field

Magnetic field

Electronic field

Electronic field

Ionic strength

Ionic strength

Areas

Sensors

Protective Clothing

Viscosity Modifiers

Liquid Chromatography

Stakeholders Focus Areas

Shape Memory

Polymers

Light Modulation Materials

Self Healing Materials

Hydrophobic Materials

Conductive Polymers

Biomimetic Materials

OpticalOptical

TextilesTextiles

Personal Care

Personal Care

AerospaceAerospace

PhysicalPhysical

BiologicalBiological

Technology/Business Accelerators and Challenges

Imp

act

Dri

vers

Need for Advanced

Materials With Controlled

Functionality

Growing Government Aided

Research

Low

High Ability to Solve Biocompatibility and

Bio-film Issues in Healthcare

Superior Functional Benefits over conventional

polymers

Wide Application

MarketsReduction of

maintenance and labor cost.

6

Short Term(1-3 years) Medium Term(4-6 years)

Ch

all

en

ges

Imp

act

Long Term (7-10 years)

Long term durability/Mechanical and

chemical stabilityLack of Process

know-how

Low

Low

High

Source: Frost & Sullivan.

Gap between laboratory and marketplace

Identifying potential partners and protection of

IP

Lack of material standardization

Note: Longer the arrows, higher the impactBusiness Drivers Business Challenges Technology Drivers Technology Challenges

Technology Trends

Early Current Future

Polymers

Shape memory polymersConductive Polymers Ferroelectric polymers

Functional Fillers

Polymeric GelsHydrophobic materialsTemperature Sensing

PolymersReinforcements

CopolymersBiopolymers Biomimetics

Advances in

nanotechnology and

functional chemistryInnovations in Chemical

formulations

Ongoing investigations in

complex structures and

formulations

7

Early Current Future

Manufacturing Processes

Spray-on CoatingsDeposition Techniques

Thin filmVapor DepositionPeel off process

Hybrid SystemsSelf Assembly

Reel-to-reel die-coating

Advances in Precision

manufacturingAdvances in deposition

processes

Advances in retrofitting

and integration of different

techniques

Recent Developments

Temperature Threshold Polymers

Light ModulationMaterials

Case Western Reserve University, USA -------- Piezochromic liquid-crystalline fluorophores--------Temperature threshold sensing devices-------Sensors and Optics.

Landec Corp, USA ------- Intelimer® polymer technology ---------- Personalcare applications.

FujiXerox, Japan---------Stimuli-responsive gel (NIPAM) containing a highconcentration of pigments -----------Electrical Signals --------Electricals Industry.

Recent

Temperature Sensitive Polymers

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Conductive

Polymers

Massachusetts Institute of Technology, USA ---------Shape-memory plastics / “molecularswitches,” ------- manufacturing of SRPs.

Recent Developments

Shape Memory Polymers

Vivamer, UK --------- Polymeric backbones ----- Healthcare as a localized drugdelivery system and therapeutic imaging.

Encapsulated Polymers

Textronics, USA --------- Textro-Polymers ---------- Protective Clothing andSport equipment.

Emerging Opportunities for Stakeholders—Dashboard SummaryComparative Assessment- Current Scenario

HealthcareHealthcare Automotive & TransportationAutomotive & Transportation Electricals & ElectronicsElectricals & Electronics

Sensors & OpticsSensors & Optics TextilesTextiles Personal CarePersonal Care

0

1

2 3

4

5

3.5

0

1

2 3

4

5

3.5

0

1

2 3

4

5

3.75

9

Factors considered include: Patent Strength, Research Efforts, Impact of drivers and challenges on industry sectors, Potentialof addressing demands in Market and Breadth of Applications

Source: Frost & Sullivan.

0

1

2 3

4

5

4.0

0

1

2 3

4

5

3.0

0

1

2 3

4

5

1.5

Key: High

1 52 3 4

Application Adoption Roadmap

MEMS

Self Monitoring

Drug Delivery

Microfluidics

Self-healing materials

Biomedical Sensors

Biofilm protection

Contamination Detection

Thermally responsive

materials for

personal care

F&B Packaging

Fuel cells

10

2013 2015 2017-18Source: Frost & Sullivan

2020

MEMSMonitoring

Devices

Delivery Devices and

ImplantsElectronics Integrated

Textiles

Flexible Chips & Displays

Bio-separation

Detection

Potential Scenarios for Convergence across Industries Opportunities in Healthcare, Textiles and Energy Harvesting

Polymer Chameleons

Smart Energy manage

ment

Targeted Drug

Delivery

Targeted case specific drugs for specific tissues . Controlled release of drugs on specific sites.

Manufacture of fuel cells and energy storage materials.

Stakeholders include Stanford University, USA & Northwestern University, USA.

Stakeholders include Tokyo Institute of Technology and National University of Singapore.

11

Smart Textiles

Personalized Implants

Protective Clothing that can be fine tuned based on external atmospheric conditions.

Leveraging 3D printing for personalized implants to increase patient turnaround time.

Stakeholders include Creganna & mNemoscience GmbH

Stakeholders include 3DO and M2 Polymer Technologies Inc.

New Market Creation

Increased interaction between Electronics and Textile Industries

Key Success Factors for Commercialization

•Scalability tests to find the suitability of the polymers for large scale adoption across various sectors, esp. in case of electronics and healthcare.

•Collaborative research focusing on bridging the industry needs with academic capabilities.

•Establishing knowledge transfer networks

Bridging the Gap

between Academia

and Industry

Scalability for large

scale production

Standard Quantitative

Establish USP for application sector

Establish Supply Chain

Alignment of Design

12

•Pre- market harmonization

•Regulations to govern the use of SRP

• Framing industry standards

•Understand •Understand chemistry between the polymeric structure and their interactions.

•Data on long term durability, safety and reliability of these polymers, esp. for healthcare.

Standard Regulatory Framework

s and Guidelines

Quantitative data on

Characteristics, Safety

and Reliability

Alignment of Manufacturing and Testing processes

Standardization of materials and methods

Commercialization

Year of Impact Market Potential Global Footprint

IP Activity Funding Breadth of Industries

To Summarize….

13

Potential Points of Convergence

Next Steps

Develop Your Visionary and Innovative SkillsGrowth Partnership Service Share your growth thought leadership and ideas or

join our GIL Global Community

14

Join our GIL Community NewsletterKeep abreast of innovative growth opportunities

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For Additional Information

Liz Clark

Corporate Communications

Chemicals, Materials, & Food

210-477-8483

[email protected]

Aarthi Janakiraman

Industry Analyst

Materials & Coatings

(91) 044-66814102

[email protected]

17

Arpita Mukherjee

Senior Research Analyst

Materials & Coatings

(91) 033-66813359

[email protected]

Aravind Chander V

Industry Manager

Materials & Coatings

(91) 044-66814103

[email protected]


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