May/June 2014 www.pulmonarypaper.org 11
This issue marks the fourth year
the Pulmonary Paper is publishing
its portable oxygen concentrator
(POC) chart. This year, we’re adding a
checklist of important questions to ask
before purchasing, renting or simply using
a POC.
POCs are seeing even wider acceptance
among oxygen users, home medical equip-
ment dealers and clinicians in the field.
Manufacturers have responded – POC avail-
ability is at an all-time high, with a majority
of current POC models being released within
the last five years. However, throughout
the home respiratory care spectrum there
remain many mis conceptions relating to
the performance capabilities and limitations
of POCs.
Perhaps the most important factor to
consider regarding POCs is that one size
does not fit all. Each POC has limited
oxygen production ability and, generally,
the smaller and lighter the POC is, the
smaller its production capacity is, meaning
it will meet fewer users’ needs than the
larger POCs. Since most oxygen users would
naturally prefer a smaller, lighter device,
manufacturers have made a con scious trade-
off in performance ability that allows for
the POC to be as little and lightweight as
possible while sacrificing oxy gen production
capacity, thereby limiting the total number
of users that could adequately oxygenate
on the device in some or all of their daily
activities.
The smallest available POC weighs
around 3 pounds and produces around
333 mL of oxygen per minute, or 0.33 LPM,
and can only deliver its oxygen in pulse
form while the user is inhaling. It features
no adjustable pulse flow settings, and as the
user breathes faster, the pulse flow volume
delivered actually decreases. Nevertheless,
since this POC is the smallest POC available,
it has clear appeal to a wide range of users,
even though some of them may not know
that the device may not be able to keep them
adequately oxygenated during some or all
of their daily activities.
At the other end of the spectrum, there
are several larger POCs available that can
produce 3000 mL of oxygen per minute, or
3.0 LPM. These units can provide oxygen
at both continuous flow settings and a wide
variety of pulse flow settings, making them
viable options for a wide range of oxygen
users. Yet these POCs can weigh anywhere
from 12 to 20 pounds, and this is before
Portable Oxygen Concentrators:
The Chart and the Checklist
Continued on page 12
12 www.pulmonarypaper.org Volume 25, Number 3
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adding the weight of the various accessories
that come with the POC. To many users,
that is just too much size and weight to
routinely carry with them no matter how
well the POC can oxygenate them.
Unfortunately, despite the variety of
small- and large-form POCs available, POC
options for oxygen users with high flow
needs is still limited. Users with needs in
the 4 LPM to 6 LPM continuous flow range
may find they can oxygenate well in some
or all of their daily activities on some of
the larger POCs set to their higher pulse
Perhaps the most important
factor to consider
regarding POCs is that
one size does not fit all.
settings. However, those with needs greater
than 6 LPM may not be able to routinely use
any of the POCs currently available, though
there may be some select applications and
scenarios where one of these larger POCs
could be an option for use.
Following is a checklist of questions
anyone considering use of a POC should
take with them when deciding what POC
to buy or use. These questions cover what
we feel are some of the most important
factors to think about when determining
what POCs are options for the user, but this
is not meant to be an exhaustive list. The
more these questions are asked, the more
manufacturers and dealers will need to be
clear on the answers. For now, don’t expect
to get immediate answers to all of them, but
do try and find out as much information as
you can before making a decision.
Continued from page 11
May/June 2014 www.pulmonarypaper.org 13
Q What is the oxygen production capac
ity of the POC?
Oxygen production capacity tells you
how much oxygen the POC is capable
of producing per minute. Smaller POC
units tend to produce less oxygen per
minute than larger units, and will meet
a smaller range of user needs than their
larger counterparts.
Oxygen production is typically given
in milliliters (mL) per minute. 1000 mL/
min = 1 LPM.
Q Is the POC continuous flow capable?
Not all POCs can provide con-
tinuous flow oxygen. Many of the
smaller POCs are pulse-only devices,
meaning that all oxygen volumes are
delivered via pulses as the user breathes
in. Pulse delivery of oxygen has
fundamentally different characteristics
compared to con tinuous flow oxygen
deliv ery, so do not assume pulse settings
have liter flow equivalency (e.g., 2 pulse
setting = 2 LPM). Use of a pulse-only
POC during sleep is not recommended
unless the user has completed an overnight
study with the device showing that
they stayed oxygenated throughout the
night.
Q What is the range of pulse settings
available – and continuous flow
settings if applicable, and what are the
associated pulse volumes at resting and
active breathing rates?
For example, a POC with settings of
1, 2, and 3 may deliver:
1 = 16 mL @ 15 BPM 8 mL @ 30 BPM
2 = 32 mL @ 15 BPM 16 mL @ 30 BPM
3 = 48 mL @ 15 BPM 24 mL @ 30 BPM
Pulse settings on POCs will vary from
device to device – one POC model set
to “2” pulse delivery will not be the
same on another POC model set to “2”.
Additionally, some POCs reduce the pulse
volume deliv ered at a setting as the user’s
breath rate goes up (aka, minute volume
delivery), whereas others keep the pulse
volume the same no matter the rate of
breathing (aka, fixed pulse delivery). Some
units combine both! Know that on minute
volume delivery POCs and some fixed
pulse POCs, you may need to increase
the pulse setting when you are active to
maintain adequate oxygenation.
Q What is the POC’s typical battery life
for each pulse setting at resting and
active breath rates? What are the battery
run times for continuous flow settings, if
available?
Battery life can be dependent on a
variety of factors. For example, a POC
with settings of 1, 2 or 3 may operate from
a full battery charge for:
1 = 4 hrs @ 15 BPM 3 hrs @ 30 BPM
2 = 3.5 hrs @ 15 BPM 2.5 hrs @ 30 BPM
3 = 2.5 hrs @ 15 BPM 1.5 hrs @ 30 BPM
Continuous flow opera tion, when
available, will go through battery power
much faster than a setting in pulse
operation. In pulse delivery, the setting
selection and the user’s breath rate are
significant factors in determining battery
life. Knowing how long each battery will
Continued on page 14
14 www.pulmonarypaper.org Volume 25, Number 3
last in the conditions it will be used in can
help to determine how long the user can
be away from a power source or will need
to swap in a freshly charged battery. Per
FAA regulations, traveling with a POC
requires bringing enough battery power
to last the user 1.5 times the duration of
the flight.
Q Is the device limited when being pow
ered by the DC power supply?
Some users find out too late that they
can’t use the device as they normally
would when using DC power. DC power
is provided through fixtures like car
adapters, and most POCs come with a
DC supply for travel purposes.
However, some POCs have limits on
their functionality when operating from
DC power. These limits may include non-
operation at higher flow and pulse settings
and/or the inability to charge the battery
while the device is in use.
Q How much does the POC unit weigh,
with and without all of the included
acces sories?
Manufacturers often will only report
what the unit plus one battery weighs,
which ignores the weight that is added
when toting a wheeled cart, AC/DC pow-
er supplies, extra batteries and other
accessories.
Carrying all of these addi tional pieces
can significantly add to the total weight
of the POC, which can make a difference
to those who may have trouble lifting and
maneuvering the equipment.
Q What is the manufacturer’s warranty
on the POC? If the POC needs repair
(under warranty or not under warranty),
will a substitute POC be supplied while it
is in for service?
If you are buying a POC new, be aware
that the warranty will typically cover the
unit, but not the battery, which will have
its own warranty terms. While the repair
cost may be covered, users who return a
POC for warranty service may be asked
to pay for shipping costs. Some, but not
all, dealers will provide a backup unit
while the defective POC is in for repair. If
a POC is bought used, the manufacturer’s
warranty may not be honored, so check
to see if the seller offers any warranty
guarantees.
The POC comparison chart compiles
information from manufacturer specifica-
tions, device manuals and manufacturer-
supplied material found in the American
Association of Home Respiratory Care’s
A Guide to Portable Oxygen Concen
trators, which can be downloaded for free
at https://www.aarc.org/resources/oxygen_
resources/portable_oxygen_concentrators_
guide.pdf. Please note that some POCs
previously included have been discontinued
and are no longer listed. Every effort has
been made to present the most accurate and
up-to-date infor mation in this comparison
chart – if you no-
tice an error please
contact Ryan
Diesem at rdiesem
@inspiredrc.com.
Continued from page 13
May/June 2014 www.pulmonarypaper.org 15
1,000 mL/min(1.0 LPM)
1 to 5
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 66 mL
30 BPM: 33 mL
6 lbs.
2.0 hours
12,000 ft.
333 mL/min(0.33 LPM)
NoneSelectable
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 22 mL
30 BPM: 11 mL
3 lbs.
1.5 hours
10,000 ft.
AirSep AirSep AirSep Inogen Focus™ FreeStyle™ 3 FreeStyle™ 5 One G2
PRODUCTION AND DELIVERY
Please consult with your doctor or therapist before deciding to use or purchase any of these devices.
2014 Portable Oxygen ConcentratorsINTERMITTENT FLOW (PULSE ONLY) POCS
Maximum Oxygen
Production (mL/min)
Available Settings
Pulse Delivery
Type
Maximum Delivered Pulse
Volume
Unit & Battery (Approx.)
Approx. Battery Time at Pulse
Setting 2
Max. Altitude
500 mL/min(0.5 LPM)
1 to 3
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 33 mL
30 BPM: 17 mL
4 lbs.
2.5 hours
12,000 ft.
1,260 mL/min(1.26 LPM)
1 to 6
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 60 mL
30 BPM: 30 mL
7 lbs.
4.0 hours(est.)
10,000 ft.
DOSE VOLUMES PER BREATH***2 LPM Continuous Flow: 15 BPM: 44mL 30 BPM: 22mL
4 LPM Continuous Flow: 15 BPM: 88mL 30 BPM: 44mL
6 LPM Continuous Flow: 15 BPM: 133mL 30 BPM: 66mL
WEIGHT (UNIT + STD. BATTERY); ADD UP TO 5LBS. FOR ACCESSORIES
STANDARD SINGLE BATTERY OPERATION TIMES
ALL UNITS APPROVED FOR FLIGHT BY FAA
High Flow
840 mL/min(0.84 LPM)
1 to 5
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 56 mL
30 BPM: 28 mL
6 lbs.
2.5 hours
10,000 ft.
16 www.pulmonarypaper.org Volume 25, Number 3
Inogen Inova Labs Invacare Oxus One G3 Activox™ XPO2 POC
PRODUCTION AND DELIVERY
INTERMITTENT FLOW (PULSE ONLY) POCS
450 mL/min(0.45 LPM)
1 to 3
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 30 mL
30 BPM: 15 mL
5 lbs.
4.0 hours
10,000 ft.
850 mL/min(0.85 LPM)
1 to 5
Fixed Delivery8.5 mL
per setting
43 mL
10 lbs.
3.0 hours
8,000 ft.
WEIGHT (UNIT + STD. BATTERY); ADD UP TO 5LBS. FOR ACCESSORIES
STANDARD SINGLE BATTERY OPERATION TIMES
ALL UNITS APPROVED FOR FLIGHT BY FAA
Maximum Oxygen
Production (mL/min)
Available Settings
Pulse Delivery
Type
Maximum Delivered Pulse
Volume
Unit & Battery (Approx.)
Approx. Battery Time at Pulse
Setting 2
Max. Altitude
Please consult with your doctor or therapist before deciding to use or purchase any of these devices.
2014 Portable Oxygen Concentrators
840 mL/min(0.84 LPM)
1 to 4
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 56 mL
30 BPM: 28 mL
5 lbs.
3.0 hours(est.)
10,000 ft.
****Approximate Continuous Flow volumes at 2, 4, and 6 LPM are provided for comparison to maximum volumes delivered by the selected POC.
DOSE VOLUMES PER BREATH***2 LPM Continuous Flow: 15 BPM: 44mL 30 BPM: 22mL
4 LPM Continuous Flow: 15 BPM: 88mL 30 BPM: 44mL
6 LPM Continuous Flow: 15 BPM: 133mL 30 BPM: 66mL
Precision DeVilbiss® Invacare EasyPulse iGo Solo2®
PRODUCTION AND DELIVERY
3,000 mL/min(3.0 LPM)
1 to 6Continuous 1 to 3 LPM
Fixed Delivery 14 mL
per setting
84 mL
19 lbs.
4.7 hours(20 BPM)
13,123 ft.
May/June 2014 www.pulmonarypaper.org 17
WEIGHT (UNIT + STD. BATTERY); ADD UP TO 5LBS. FOR ACCESSORIES
STANDARD SINGLE BATTERY OPERATION TIMES
ALL UNITS APPROVED FOR FLIGHT BY FAA
Maximum Oxygen
Production (mL/min)
Available Settings
Pulse Delivery
Type
Maximum Delivered Pulse
Volume
Unit & Battery (Approx.)
Approx. Battery Time at Pulse
Setting 2
Max. Altitude
Please consult with your doctor or therapist before deciding to use or purchase any of these devices.
2014 Portable Oxygen Concentrators
780 mL/min(0.78 LPM)
1 to 5
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 52 mL
30 BPM: 26 mL
7 lbs.
3.2 hours(est.)
9,000 ft.
3,000 mL/min(3.0 LPM)
1 to 6Continuous
0.5 to 3 LPM
Minute Vol.Delivery: Dose
decreases as rate rises
15 BPM: 133 mL
30 BPM: 66 mL
20 lbs.
3.5 hours
10,000 ft.
INTERMITTENT FLOW (PULSE ONLY) POCS CONTINUOUS FLOW POCS
O2 Concepts Respironics™ SeQual® SeQual® OxLife Independence SimplyGo Eclipse 3/5 eQuinox
PRODUCTION AND DELIVERY
2,000 mL/min(2.0 LPM)
Pulse 1 to 6Continuous
0.5 to 2 LPM
Combination Fixed/Minute
Vol. Delivery**
15 BPM: 72 mL
30 BPM: 66 mL
10 lbs.
3.0 hours(20 BPM)
10,000 ft.
3,000 mL/min(3.0 LPM)
Pulse 1 to 6*Continuous
0.5 to 3 LPM
Fixed Delivery16 mL
per setting
96 mL*
19 lbs.
5.1 hours(12 BPM)
13,123 ft.
18 www.pulmonarypaper.org Volume 25, Number 3
3,000 mL/min(3.0 LPM)
Pulse 1 to 6*Continuous
0.5 to 3 LPM
Fixed Delivery16 mL
per setting
96 mL*
14 lbs.
2.75 hours(12 BPM)
13,130 ft.
WEIGHT (UNIT + STD. BATTERY); ADD UP TO 10 LBS. FOR ACCESSORIES
STANDARD SINGLE BATTERY OPERATION TIMES
ALL UNITS APPROVED FOR FLIGHT BY FAA
Maximum Oxygen
Production (mL/min)
Available Settings
Pulse Delivery
Type
Maximum Delivered Pulse
Volume
Unit & Battery (Approx.)
Approx. Battery Time at Pulse
Setting 2
Max. Altitude
CONTINUOUS FLOW POCS
Please consult with your doctor or therapist before deciding to use or purchase any of these devices.
2014 Portable Oxygen Concentrators
3,000 mL/min(3.0 LPM)
Pulse 1 to 6Continuous 1 to 3 LPM
Fixed Delivery16 mL
per setting
96 mL
19 lbs.(w/2 batteries)
2.9 hours****(20 BPM)
13,123 ft.
****The Eclipse models also have pulse settings of 128, 160 and 192mL, but have additional breath rate restrictions for use. See Eclipse 3 manual for more information.
****The SimplyGo has two IF delivery modes: Pulse Mode and Night Mode. Shown volumes are for Pulse Mode. Night Mode has Minute Volume Delivery.
****The Independence is packaged with (2) batteries that can be used simultaneously, doubling the reported operating time.