Positions available

Cell, Vol. 55, No. 5, December 2, 1988

Positions Available

Cell C lassified Information Cell publishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $225 for a quarter page, $425 for a half page, and $795 for a full page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next available issues are as follows (all material due close of business on due date):

*Jan. 13,1989 issue: copy due Dec. 9,1988 *Jan. 27,1989 issue: copy due Dec. 23.1988 *Feb. lo,1989 issue: copy due Jan. 6,1989 *Feb. 24,1989 issue: copy due Jan. 20,1989 *Mar. lo,1989 issue: copy due Feb. 3,1989 *Mar. 24,1989 issue: copy due Feb. 17,1989 -Apr. 7, 1989 issue: copy due Mar. 3,1989 *Apr. 21,1989 issue: copy due Mar. 17, 1989

*May 5,1989 issue: copy due Mar. 31,1989 *May 19,1989 issue: copy due Apr. 14,1989 *June 2,198g issue: copy due Apr. 28,1989 *June 16,1989 issue: copy due May 12,1989 *June 30,1989 issue: copy due May 26,1989 l July 14,1989 issue: copy due June 9,1989 *July 28,1989 issue: copy due June 23,1989 dug. 11,1989 issue: copy due July 7,1989

Advertisements should be sent to: Allison Kemmerer

Clartifled Ad Department cell

50 Church Street Cambridge, MA 02129 (617-991-7059).

Postdoctoral Position Molecular Biology University of California, San Francisco

A postdoctoral position is available for an individual with molecular biology background to pursue studies on adrenergic and cholinergic receptors, signal transduction, and hypertrophy in cardiac muscle cells. Funding will be available for at least two years. Salary $25,~30,000 commensurate with experience. Opportunity for independent program development and supervision of ongoing research.

Send resume and names of three referees to:

Dr. Joel S. Karllner Chief, Cardiology Section (1llC) Veterans Administration Medlcal Center University of California, San Francisco 4150 Clement Street San Francisco, CA 94121.

The University of California, San Francisco is an Equal Oppotfunity/Affrmati~ Action Employer.

Assistant Professor of Biological Chemistry Johns Hopkins University School of Medicine

The Department of Biological Chemistry at The Johns Hopkins University School of Medicine invites applications for a tenure track position at the assistant professor level. The department is looking for candidates with a commitment to excellence in research and teaching in biochemistry. Applicants should submit curriculum vitae, list of publications, including representative reprints, three letters of recommendation and a summary of research plans to:

Dr. Gerald W. Hart Search Commlttee Chairperson Department of Blologlcal Chemistry The Johns Hopkins University School of Medicine Baltimore, MD 21205. To insure full consideration, applications should be received by January 31,1999.

Equal Opportunity/Aifirmative Action Employer.

c%Nl, Vol. 55, No. 5, December 2,198tl

Postdoctoral Research Opportunities New York University Medical School

Applications are invited for postdoctoral research beginning in winter/spring 1999 to study:

(1) Mechanisms of signal transduction and induction of gene transcription through cell surface receptor activation of mammalian cells by cytokines; and (2) Role of interferons and other cytokines in the regulation of cell growth.

Experience in eukaryotic molecular biology and/or biochemistry is desirable. Applicants must be eligible for funding from the NIH (US citizens and permanent residents). Send letter of application, curriculum vitae, and names and addresses of three references to:

Dr. David E. Levy Department of Pathology NYU Medical Center 550 First Avenue New York, NY 10016. Minorities are particularly encouraged to apply.

Postdoctoral Research Associates Cell and Molecular Biology of

Lymphocytes HHMl/Yale University

A position is available to qualified applicants to work on the cell biology of antigen processing using a model antibody to peptide:class II MHC complexes. A background in immunoelectron microscopy, cell fractionation, and the cell biology of endocytosis is desirable.

A position is also available to work on the cell and molecular biology of CD4:T cell receptor interactions on T cells. Experience in gene transfection, gene cloning, and vector construction is desirable.

Charles A. Janeway, Jr. Section of lmmunobiology Howard Hughes Medical lnstltute Yale University School of Medicine 310 Cedar Street New Haven, CT 06510. Yale Unbrsify and the Howard Hughes Medical htitute are Equal Opportunity Employers.

Assistant Professor

Department of Microbiology The University of Tennessee

Knoxville, Tennessee

QUALIFICATIONS: Doctoral degree and at least two years postdoctoral experience in microbiology or closely allied biological science; demonstrated research productivity in molecular biology and potential excellence in teaching.

RESPONSIBILITIES: Graduate and undergraduate teaching in microbiology/molecular biology, establishment of a productive independent research program, and academic responsibilities normally associated with a tenure track faculty position.

STARTING DATE: August 1,1989.

Applicants should submit a letter of interest accompanied by a curriculum vitae, a description of the applicant’s research program and career objectives, and the names, addresses, and telephone numbers of three individuals who can evaluate the applicant’s qualifications for the position. Applications from women and minorities are especially invited, All material should be sent to: Dr. Stuart Rlggsby, Chairman, Search Committee, Department of Mlcroblology, University of Tennessee, Knoxville, TN 3799BOB45. Nominations should be made as soon as possible. Evaluation of applications will begin in January, 1989.

The Univsrsity of Tennessee is an EEO\AA \ Title K\Secticn 504 Employer.

Cell, Vol. 55, No. 5. December 2, 1988

Division of Orthopaedic Surgery University of California, San Diego

The Division of Orthopaedic Surgery has an opening for a postdoctoral research fellow in the field of molecular/cell biology. lt is desired that the candidate be skilled in basic recombinant DNA techniques, have experience in mammalian cell culture; mRNA isolation and characterization (i.e. northern blotting and in situ hybridization); and protein purification. The candidate should express interest in the changes of connective tissue genes (i.e. collagen, fibronectin, and actin) as a function of tissue injury. Preference will be given to candidates whose research will complement existing orthopaedic programs (i.e. aging effects on connective tissue; healing of cartilage, tendons, and ligaments; homeostasis response of connective tissues to physical forces; and stress deprivat- ion). Salary ranges from $16,000-24,ooO depending on experience. Excellent research environment, health benefits, and travel funds for scientific meetings are provided. Please send curriculum vitae and reference letters to: Prof. Davld Amlsl, Director, Orthopaedlc Biochemistry, UCSD M-030, La Jolla, CA 92093. UCSD is an Equal Oppotfunify Employer.

Faculty Position Department of Genetics University of Washington

The Department of Genetics seeks candidates for a tenure track appointment at the rank of assistant or associate professor, to begin in 1989 or 1990. The successful applicant will have a notable record of achievement in basic research and a strong commitment to both undergraduate and graduate education. Areas of particular interest to the Depart- ment include neurogenetics, mammalian genetics, and plant molecular genetics. Applicants should arrange to have three letters of recommendation sent and should submit a curriculum vitae and a brief description of research interests by March 1, 1989, to:

Search Committee Department of Genetics, SK-59 University of Washington Seaffle, WA 98195.

The Uniwwsify of Washington is an Equal Opporfunify/ Affi~afiwa Action Employer.

c\ %f$ Faculty Positions pi The Ohio State University is expanding its search for

faculty at all levels with expertise in gene expression in the nervous system to complement existing strengths in developmental neurobiology, neural plasticity and regeneration, structural chemistry, receptor-mediated events and molecular genetics. The College of Medicine and the Biotechnology Center have designated Molecular Neurobiology as a top priority for development. Three to five tenure track positions at the Assistant to Full Professor level are available now at the Ohio State Biotechnology Center, with appointments in appropriate academic departments. At leas: five additional appointments will be made as the core group develops. Can didates qualified for appointment to Professor may also be considered for the position of Associate Director of the Biotechnology Center.

These positions offer newly remodeled laboratories, start-up funds and the opportunity to participate in the development of new interdisciplinary programs at a University committed to excellence in research and graduate education.

Send nominations, or applications including C.V., a brief statement of research plans, and the names of three references to: Dr. P.E. Kolattukudy. Director, Ohio State Biotechnology Center, 206 Rightmire Hall, 1060 Carmack Road, Columbus, OH 43210-1002. Equal Op portunity/Affirmative Action Employer.

Cancer Pharmacologist Childrens Hospital of Los Angeles

A tenure track position at the assistant professor level is open in the Pharmacology Section of the Division of Hematology-Oncology, Dept. of Pediatrics, University of Southern California at Childrens Hospital of Los Angeles. Candidates will also be considered for a joint appointment in a basic sciences department and membership in the USC-Norris Comprehensive Cancer Center. Excellent laboratory space is available on the pharmacology floor of our new research tower. Candidates should have a Ph.D. in pharmacology or biochemistry and postdoctoral training in cancer pharmacology or molecular biology related to potential anticancer drug therapy. Send curriculum vitae, representative publications, a statement of research interests, and the names of three references to: John Holcenberg, M.D. Division of Hematology-Oncology Children8 Hospital of Los Angeles P.O. Box 54700 Los Angeles, CA 99054-9700. An Equal Opportunify Employer.


Postdoctoral Position Cell Biology/Molecular Biology

Rockefeller University

A postdoctoral position is available immediately to study signal transduction by the epidermal growth factor receptor and &B protein, Some experience in molecular biology or peptide chemistry and tissue culture preferred. Candidate should be a recent Ph.D. graduate.

Send curriculum vitae and names of two references to:

Dr. Stuart Decker Rockefeller University

1230 York Avenue New York, NY 10021.

Molecular/Cellular Biologist Iowa State University

Iowa State University invites applications at any level for a tenure track or tenured faculty position. The successful applicant will be expected to lead a vigorous, externally funded research program involving state-of- the-art molecular, cellular, and/or genetic approaches to study areas related to endocrinology such as: signal transduction, control of secretion, or the regulation of growth and development. This position is part of a multi million dollar, campus-wide effort to promote excellence in molecular biology and biotechnology. Central nucleic acid, protein, image analysis, fermentation, molecular structure and cell-sorting facilities with the most advanced equipment available have already been estab. lished. Salary will be competitive and research start-up funds of up to $15QCNXJ are available. Teaching responsibilities will be modest. A description of research interests, curriculum vitae, and at least three references should bs sent to: Dr. T. Ingebritsen, Dept. of Zoology, Iowa State University, Ames, IA 50011, by January 15 1999. Women, minorities, and members of other ptM9cted groups an9 strong& encouraged tc apply. ISU is an Equal Opportunity/Afirmativs Action Employer.

CELL BIOLOGIST YALE UNIVERSITY SCHOOL OF MEDICINE

The Department of Cell Biology, Yale University School of Medicine, is accepting applications for a tenure track position at the assistant professor level with a starting date no later than July 1, 1989. Preference will be given to candidates with expertise in the in vitro assembly of the nucleus, or the application of confocal m icroscopy to living cells. However, applications from investigators in all areas of cell biology will be welcomed. It is anticipated that successful candidates will establish independent, externally funded research programs and be willing to collaborate with other members of the Department whose research interests focus on the structure, function and dynamics of intracellular membranes and organelles. Involvement in teaching of cell biology to medical and graduate students and supervision of graduate students is required. Candidates must hold the Ph.D. or M .D. degree and have at least two years of postdoctoral experience.

Applicants should submit their curriculum vitae, statement of research and teaching interests and names of three references before February 1,1989 to:

Dr. James D. Jamieson, Chairman Department of Cell Biology

Yale University School of Medicine 333 Cedar Street

New Haven, CT 06510-0082

Yale University is an equal opportunity/affitmative action employer.

Cell, vol. 55, No. 5. December 2, 1988

Post Doctoral Position Available

Immediately To study Fc (IgG) receptors on natural killer cells and granulocytes. The projects focus on: (1) mechanisms of signal-transduction and gene transcription upon FcR-ligand interaction; and (2) regulation of FcR function/expression by ligands and lymphokines. Experience in membrane protein biochemis- t v3:

and/or molecular biology is preferredThe rstar Institute is a non-profit biomedical

research facility located on the University of Pennsylvania campus in Philadelphia. Wistar is organized as a community of laboratories which fosters both individuality and creativi- ty using a multi-disciplinary approach to our research. Candidates should send curriculum vitae and the names of three references to: Dr. Bite Perussia, Associate Professor, The Wistar Institute, 36th & Spruce Sts., Phlla., PA 19104. Equal Oppor- tunity Employer, M/F

Postdoctoral Position University of Pennsylvania

School of Medicine

A postdoctoral position is available for a recent Ph.D. to study molecular mechanisms of lymphocyte activation, Research will focus on the involvement of immediate-early response genes in transducing receptorgenerated signals or the biochemical dissection of receptor signalling using signalling mutants. Experience with molecular biological and/or biochemical techniques is required.

Send curriculum vitae and names of three references to:

Dr. John G. Monroe Department of Pathology Unlverslty of Pennsylvania

School of Medicine Room 274-John Morgan Bldg./G3 Philadelphia, PA 19104.

Postdoctoral Position

Molecular Biology of Cardiac and Skeletal Muscle Development

University of California, San Francisco

A postdoctoral position is available immediately to study transcriptional regulation of contractile protein genes during the differentiation of cardiac and skeletal muscle cells. Current emphasis is on the characterization and isolation of trans factors interacting with the cardiac- and skeletal muscle-specific regulatory elements governing transcription of the cardiac troponin T gene promoter (see J. Cell Biol. 107: 573, 1988; and Proc. Nat. Acad. Sci. 85: 8404, 1988). Send letter of interest, curriculum vitae, and the addresses and telephone numbers of three references to:

Dr. Charles P. Ordahl s-1334/-x 0452 University of Callfornla, San Francisco San Francisco, CA 94143.

L

Postdoctoral Position Genetics of Scrapie Prions

and Murine Hosts McLaughlin Research institute

This multidisciplinary collaborative project with Dr. S. Prusiner’s UCSF group emphasizes formal and molecular genetics as tools to reveal mechanisms of prlon replication. McLaughlin Research Institute is a small facility in Great Falls, Montana specializing in mammalian genetics. Excellent facilities and more than 100 distinct inbred strains of mice provide an outstanding genetic resource. Great Falls provides a pleasant environment, low cost of living, and excellent schools. Outdoor recreational opportunities are superb. Applicants should have a strong research background in genetics, molecular biology, or immunology. The position provides the opportunity to gain expertise in mammalian genetics while pursuing a fascinating biological problem. Please send curriculum vitae to: George A Carlson, Ph.D., Cc-Director, McLaughlin Research Institute, 1626 3rd Avenue North, Great Falls, MT 59401, (406) 4526206. An Aftirmatiw Action/Equal Opportunify Employer.


Postdoctoral Fellow in Antileukemic and Antiviral Drug

Pharmacology Chiidrens Hospital of Los Angeles

A postdoctoral fellow position is open with funding for two to three years in the Division of Hematology/ Oncology, Department of Pediatrics in the Pharmacology Section, University of Southern California at Childrens Hospital of Los Angeles for studies in the cellular pharmacology of anti-HIV and antileukemic nucleoside analogues. Fully equipped laboratory space is available for use in the new Research Tower. Send curriculum vitae, a statement of research interests, and the names of three references to:

Vassllios I. Avramls, Ph.D. Division of Hematology/Oncology Children8 Hospital of Los Angeles P.O. Box 54700 Los Angeles, CA 90054-0700.

An Equal Opportunity Employer.

MOLECULAR DEVELOPMENTAL

BIOLOGIST . ..with excellent scientific credentials to develop independent program at appropriate professorial rank from assistant through full professor in the tenure track. Submit curriculum vitae, a short statement of future plans and direct three letters of recommendation to be sent to Dr. Gerald Litwack, Deputy Dlrector. Feis institute for Cancer Research

and Molecular Biology Temple University School of Medicine 3420 North Broad Street Philadelphia, PA 19140 An equal opportunity employer

Molecular Virologist Washington State University

The Department of Microbiology at Washington State University (WSU) invites applications for a tenure track faculty position at the assistant/associate professor level. Preference will be given to individuals with research interests in the molecular basis of pathogenesls. Applicants must have postdoctoral training. The successful candidate will be expected to establish an active research program and participate in graduate, medical student, and undergraduate teaching. Send curriculum vitae, statement of research interests and professional objectives, and names of three references to: Dr. LP. Mallavia Search Committee Department of Microbiology Washington State University Pullman, WA 99184-4340. Application deadline January 3, 1989 or until position is filled. An Equal Oppoftuni&/497rmathm Action Educator and Employer. Protected group members am encouraged tc apply.

Postdoctoral Fellow

Seeking a postdoctoral fellow to participate in the mutagenesis and mammalian cell expression of the envelope glycoprotein of the HN-1 retrovirus for structural and X-ray crystallographic studies. Competence in recombinant DNA technology and an interest in protein structure are essential. Experience in protein chemistry and/or immunology is desirable. This grant-funded position is available immediately and is part of an ongoing collaborative project with Dr. Don Wtley of Harvard University. lt is anticipated that the great majority of time will be spent at Genentech in South San Francisco, CA with an opportunity to also spend time in Cambridge, MA, Please send a resume of educational background, experience, and publications with the names of three references to: Dr. Phillip Berman, Department of Developmental Biology, Genentech, Inc., 480 Polnt San Bruno Blvd., South San Francisco, CA 94080. We actiwaly support AMrmathe Action and Equal Employment Opportunity. Women and minodties aTB encouraged tc apply.

GENENTECH, INC.

Cell, Vol. 55, No. 5, December 2.1988

CAREER OPPORTUNITIES ONCOGENE SCIENCE is expanding its basic discovery research and product development programs in the application of oncogene technology to innovative drug development. We currently have postdoctoral and staff scientist positions available in the following general areas:

MOLECULAR BIOLOGY

l Gene Cloning l Eukaryotic Gene Expression l Transcriptional Regulation

MECHANISMS OF ONCOGENE ACTIVATION

l Gene Amplification l Chromosomal Rearrangements l Point Mutations

SIGNAL TRANSDUCTION

l PI Turnover l Protein Kinases l G Proteins

PROTEIN BIOCHEMISTRY

l Protein Purification l Solid Phase Peptide Synthesis l Protein Characterization

lMMUNOLOGY/ IMMUNOCHEMISTRY

l Hematopoietic Factors l Immunoassay Design l Hybridoma Development

CELL BIOLOGY

l Tissue Culture l In Vitro Drug Evaluation l Wound Healing

The Company also has openings in its patent and business development/ marketing groups for individuals with Ph.D.s and up to three (3) years’postdoctoral experience in molecular biology/drug discovery Prior patent or business/marketing experience, while desirable, is not required.

academic institutions in the New York City metropolitan area.

Oncogene Science offers an excellent compensation and benefits package. Qualified candidates should send their resumes, including a list of publications and references to:

Oncogene Science is strategically located on the North Shore of Long island, with ready access to major

Personnel Administrator 350 Community Drive Manhasset. New York 1 1030


Faculty Position in Molecular Biology Tuskegee University

The Department of Biology at Tuskegee University invites applications from molecular biologists who use molecular genetic approaches to study fundamental problems in biology. The position is at the senior faculty level and is available immediately. A completely equipped biotechnology laboratory is available to the appointee. Our search will consider candidates in all areas of molecular biology research. Applicants should have a doctoral degree, postdoctoral experience, and proven ability for independent research. The appointed candidate will join an active graduate program and is expected to develop a strong independent research program. Please forward curriculum vitae, a research proposal, summary of teaching interests, and three references to: Dr. J.H.M. Henderson Chairman of the Molecular

Biology Search Committee Department of Biology Tuskegee University Tuskegee, Alabama 36066.

I Chairman, Anatomy Search Committee Professor, Department of Pathology

& Laboratory Medicine University of Pennsylvania School

of Yedkine 6th Floor Founders Pavilion Philadslphla, PA 191644263

CHAIRMAN Department of Anatomy

The University of Pennsylvania School of Medicine is seeking applicants for the position of Professor and Chairman of the Department of Anatomy.

Application is invited from individuals with outstanding achievement in research, demonstrated leadership ability, and appreciation for the role of a department of anatomy in educating both medical and graduate students. We are seeking candidates from a broad spectrum of disciplines and departments related to anatomy and cell, structural, neuro and developmental biology.

The University is an equal opportunity, affirmative action employer. Women and minority candidates are encouraged to apply.

Interested applicants should send curriculum vitae to:

Dtuseppe g. Pietra, M.D. . -

Senior Research Associate

Senior Research Associate (Biochemist) to study chemical processes involved in degenerative lung disease. Produce, isolate, characterize and use antibody-producing hybridomas to immunoreactive components of lung macrophages and alpha-1-antitrypsin. Research performed utilizing knowledge of production of monoclonal antibodies including alpha-l-antitrypsin, generation of antibodies using proteins (native and degraded) and synthetic peptides; lung biochemistry especially with proteases and inhibitors; biohazardous materials and tissue culture; and analytical chemistry. Research involves use of resected human material; duties involve small animal work, culture of human and other animal cells, immunoassays and other immune-techniques, radioactive procedures, HPLC and other chromatographic methodologies and enzymology. Design, implement, analyze data achieved and prepare reports for journal publication and present at research meetings. Require a Ph.D. or equivalent in Biochemistry or Chemical Analysis, Will consider ABD as meeting educational requirement. Require two years experience in job offered or two years of directly related research. Demonstrated publication record required. Full time position. $25,000 per year.

Apply at the Texas Employment Commission, Tyler, Texas, or send resume to the Texas Employment Commission TEC Building Austin, Texas 70776 J.O. #5166963.

Ad paid by an Equal Opportunity Employer.

Cell. Vol. 55. No. 5, December 2, 1988

Assistant Professor Dartmouth College

The Department of Biological Sciences, Dartmouth College, invites applications for a full time, tenure track position at the assistant professor level in cell biology, beginning July, 1969. Applicants should have completed at least two years of relevant postdoctoral experience. While applications from individuals in any area of cell biology are welcome, we are particularly interested in those using modern molecular techniques to address problems in cell division, chromatin structure, or molecular targeting. The successful candidate will initiate a vigorous, independent research program that will attract outside funding, enlist graduate student participation, and provide research experiences for exceptional undergraduates; participation in the undergraduate and graduate teaching programs of the department is also required. The College offers a generous start-up package of major equipment plus funds for expendable supplies, in addition to resources that include facilities for DNA and peptide synthesis, digital image processing, TEM, SEM, etc. Please send letters of application, curriculum vitae, reprints, a statement of research and teaching interests, and at least three letters of recommendation to:

Search Committee Biological Sciences Dartmouth College Hanover, New Hampshire 03755. Application review will begin on January 10,1999.

Dartmouth College is an Equal Opportonity/Affirmative Action Employer. Applications from wmen and members of minority groups are strongly encouraged.

PROTEIN BIOCHEMIST . ..with excellent scientific credentials to develop his/her own program preferably in the areas of growth factors or recep tors to qualify for a tenure track position at any professorial rank. Submit curriculum vitae, a short statement of future plans and direct three letters of reference to be sent to Dr. Gerald Litwack, Deputy Director.

Fels Institute for Cancer Research and Molecular Biology

Temple University School of Medicine 3420 North Broad Street Philadelphia, PA 19140

An equal opportunity employer

ASSISTANT RESEARCH MOLECULAR BIOLOGIST

The Department of Neurology, University of California, San Francisco, is seeking a molecular biologist to perform research on degenerative neurolological disorders. The candidate must have three years postddoctoral training in molecular biology. An extensive knowledge of recombinant DNA technology is required with specific experience in the following areas : (1) cDNAcloning. (2) construction and analysis of cosmid libraries. (3) identification, purification, cloning and analysis of specific nucleic acids from complex mixtures (4) design, construction and use of recombinant plasmids. (4) use of a wide variety of eukaryotic expression vectors in mammalian cell culture systems (5) DNA transfection of mammaliancells. (6)siteslirected mutagenesis. Someexpe. rience with basic techniques for protein analysis including immunoaffinitychromatographyand Western blotting isalsc necessary. The candidate will supervise a group of research. ers studying the design, construction and structure/function analysis of novel neural proteins. The candidate will also be responsible for organizing, maintaining and distributing the recombinant plasmid and cosmid constructions developed during this work. Salary range will be $36,600 to $45,700 pel annum,depending on experience. Pleasesubmit curriculurr vitae, including list of publications and the names of three references, by l/14/88 to : Dr. Stanley 8. Pruslner, Depart ment of Neurology, Universlty of California, San Fran. clsco, CA. 94143. The Uniuwsify of California is an equa opportunity/affi~ative action employer.

Cell, Vol. 55, No. 5, December 2,1988

Eminent Scholar in Protein Engineerin!

The Department of Biochemistry at The Ohlo State University invites applications and nominations of distinguished individuals for an Eminent Scholar faculty position at the rank of professor. We seek an exception. al individual who has an outstanding record and an ima! inative and highly productive research program in the area of protein engineering. The Eminent Scholar position is an Endowed Chair and the successful candidate will command a highly competitive salary, a modern, spacious laboratory, with adjacent specialized rooms, generous set up funds, and a recurring annual budget for personnel, supplies, and equipment. The primary responsibility of the Eminent Scholar is to direct a research program in protein engineering and to participate in some teaching in this area. The Eminent Scholar will also play a leadership role in determining future direct- ions of Biochemistry at Ohio State. Individuals may be nominated or may themselves apply for this position. Please submit a resume and a concise statement of research interests to: Dr. George Marzluf, Eminent Scholar Search Committee, Dept. of Biochemistry, Ohlo State University, 484 W. 12th Ave., Columbus, OH 43210. The Ohio State Uniwsily is an AA/EOE.

MOLECULAR

BIOLOGIST

Albert Einstein College of Medicine

An entry level faculty position is immediately available to join a laboratory actively involved in various aspects of reproductive immunology (Science 225: 342, 1984; Pm. Natl. Acad. Scl., USA, 87: 857, 1988).

Applicants should have a Ph.D. in molecular biology with a strong background in recombinant DNA technology. Send curriculum vitae to:

Dr. Flajesh K. Naz Director of Research

Department of Obstetrics & Gynecology Room 123 Ullmann Building

Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, New York 10461.

Postdoctoral Position RNA Processing and Stability Dartmouth Medical School

A postdoctoral position is available beginning September, 1989, to work on the regulation of polyadenyiation and RNA stability in eukatyotic cells. Experience in the techniques of molecular biology is highly desirable.

Please send a curriculum vitae, and the names of at least three references to:

Dr. Charles N. Cole Department of Biochemistry Dartmouth Medical School HB7200 Hanover, New Hampshire 03756.

Datimouth Medical School is an Equal Opportunity Employer. Women and members of minofiiy groups are encouraged to apply.

Postdoctoral Fellowships Lineberger Cancer Research Center University of North Carolina Chapel Hill

The Lineberger Cancer Research Center of the University of North Carolina at Chapel Hill will have openings in 198490 for persons completing graduate studies to train with highly qualified investigators in molecularly oriented research in virology, chemical caroinogenesis, biochemical pharmacology, cell biology and immunology. Training includes areas such as regulation of gene expression, DNA replication, mutagenesis, molecular enzymology, control of cellular proliferation, growth factors, immunogenetics, protein phosphorylation, DNA and RNAviruses, and combined programs utilizing a broad range of contemporary technology. Unique resources and core facilities housec in the Lineberger Center and strong interdisciplinary orientation enhance training. Candidates must be U.S. citizens or permanent residents. Write for brochure and application sending brief statement of interests to: Director, Uneberger Cancer Research Center, CB# 7295, Rm. 102, Chapel Hill, NC 27599. UNC’s Cancer Research Center is an Affifmetivw Action/E0 Employer.

cell, Vol. 55, No. 5, December 2, 1988

RESEARCH SCIENTWB Genzyme Corporation, located in the Boston area, is an integrated health care company committed to the discovery and development of new technologies related to protein glycosylafion and carbohydrate chemistry. Our research is focused on the applications of bio-active carbohydrates, therapeutic glycoproteins and carbohydrate polymers. We are current/y broadening our research efforts, and our expansion has created the following opportunities to join Genzyme:

We seek a Ph.D. with a strong background in oligosaccharide structural analysis. Can- didates should be familiar with instrumen- tation and techniques used in elucidating carbohydrate structures.

Two positions are available in our recombinant glycoprotein area. The first is for a Ph.D. in cell biology or related field. Experi- ence with receptor binding assays and molecular trafficking in mammalian cells is highly desirable, as well as a strong background in the biology and biochemistry of protein glycosylation.

The second position requires a Ph.D. in molecular biology with several years’ experience in mammalian gene regulation and expression. A thorough understanding of overexpression of Iherapeutic proteins in mammalian cells, and a knowledge of molecular virology is desirable.

Genzyme offers an excellent compensation package, and a stimulating research environment. For confidential consideration, please send a letter and resume to: Human Resources, Genzyme Corporation, 75 Knee/and Street, Boston, MA 02177.

An Equal Opportunity Employer

Assistant Professor Biochemistry The Ohio State University

The Department of Biochemistry at The Ohio State University invites applications for two nine month tenure track faculty positions at the level of assistant professor available October 1, 1989 or later. We welcome applications from individuals in any area of biochemistry or molecular biology but are particularly interested in candidates with expertise in proteins and protein engineering, including the areas of enzymology, membranes and membrane receptors, growth factors, signal transduction, and neurobiochemistry. We seek individuals who will establish active, original research programs, and teach general and advanced level biochemistry courses. Candidates should have a Ph.D., postdoctoral experience, and a strong record of research productivity. Please submit a resume, a concise statement of research interests, and the names and addresses of three references to: Faculty Search Committee, Dept of Blochemlttry, Ohio State Univer- sity, 484 W. 12th Ave., Columbus, OH 43210. Review of applications will begin Jan. 1. The Ohio State .!/niver- sity is an Equal Oppottunily/At?Zmatiw Action Employer.

Cell, Vol. 55, No. 5. December 2.1988

Postdoctoral Positions Eukaryotic Transcriptional Regulation The Salk Institute, San Diego

Position available to study the developmental regulation of globin genes in the chick red cell system. The mechanism of gene activation will be examined by assembling cloned globin genes into artificial minichromosomes in the presence of red cell proteins isolated from various stages of erythroid development. The effects of specific chromatin structures formed in the promoter and enhancer regions by the interaction of purified factors will be analyzed by in vitro transcription. Interested individuals should forward their curriculum vitae and three letters of recommendation to Dr. Beverly M. Emerson.

Position available to characterize transcriptional regulation of gene expression for human immunodeficiency viruses by cellular and viral transactivator proteins. Projects include functional characterization of purified transcription factors, development of in vitro systems to study fat function, and analysis of events leading to premature termination downstream of the HIV promoters. Candidates should have experience in protein biochemistry and molecular systems. Forward resume and three letters of reference to Dr. Katherine A Jones at the address listed below.

The Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla, California 92037 (619) 453-4100.

Equal Opportunity Employer M/F/H/V

Postdoctoral Position Department of Molecular Biochemistry Beckman Research Institute

of the City of Hope

A postdoctoral position is available immediately to study the mapping of human DNA polymorphisms. Projects involve the identification of DNA sequence variation, development of a mapping strategy using DNA amplification techniques, and the mapping of genetic disease loci using newly generated markers. Experience in molecular biology is desirable.

Applicants should send curriculum vitae and three references to:

R. Bruoe Wallace, Direotor Department of Moleoular Biochemistry Beckman Research Insthute of the City of Hope 1460 E. Duarte Road Duarte, CA 91010.

Postdoctoral Position Dana-Farber Cancer Institute Boston, Massachusetts

A postdoctoral position is available immediately for a two year grant to study the immunobiology of virus infection, Experience with cell culture, molecular virology, recombinant DNA technology, and/or protein biochemistry is preferred. Salary will be commensurate with experience. This position holds an appointment at Harvard Medical School. Send cufflhxdum vitae and a list of references to:

Robert W. Finberg, M.D. Associate Professor of Medicine Chief, Laboratory of Infecttour Diseases Dana-Farber Cancer Institute 44 Btnney Street Boston, MA 02115.

DFCl is an Equal Opportunity Employer.

Cell. Vol. 55, No. 5. December 2, 1988

POSTDOCTORAL EELLOWSHIPS in

MOLECULAR BIOLOGY Howard Hughes Medical Institute

at The University of Chicago Postdoctoral positions are available for study in the following areas: (I) Molecular aspects of gene expression during difieren- tiationldevelopment in human epithelia, particularly skin. Research involves transgenic mouse technology, recombl- nant DNA methods & cell culture. Emphasis: epithelial- specific gene regulation, structure/function of keratlns and epithelial-mesenchymal interactions. (2) The function and regulation of heat-shock proteins. Utilizing genetic, molecular and lmmunologlcal methods to study hs gene regulation at the level of translation and RNA solicine and to investieate the molecular functions of the m$or hsis in Saccharofices cerevisiae and Drosophila melanogaster. Applicants should submit a curriculum vitae and names of three references to:

(1) Dr. Elaine Fuchs or (2) Dr. Susan Lindquist Howard Hughes Medical Institute

Department of Molecular Genetics and Cell Biology THE UNIVERSITY OF CHICAGO

Chicago, IL 60637 The Howard Hughes Medical Institute/ The University of Chicago Is an

Equal OpportunitylAfirmatk Action Employer.

Postdoctoral Fellowship Signal Transduction in T Lymphocytes

Harvard Medical School Massachusetts General Hospital

One postdoctoral position is available to study the mechanisms of signal transduction in T lymphocytes. Mutants defective in signal transduction will be utilized to dissect the relevant pathways leading to interleukin-2 gene induction. Applicant should have a Ph.D. or equivalent in molecular biology or biochemistry and have a record of scientific accomplishment.

Please send curriculum vitae and names of two references to:

Dr. Edward T.H. Yeh Arthritis Unit

Department of Medicine Massachusetts General Hospital

Boston, MA 02114.

Postdoctoral Training McArdle Laboratory for Cancer Research University of W isconsin-Madison

Postdoctoral fellowships are available to carry out research in the area of chemical carcinogenesis at the McArdle Laboratory for Cancer Research. Excellent research environment. Faculty and their research interests are listed below: Norman Drinkwater: Molecular mechanisms of chemical carcinogenesis and mutagenesis. William E. Fahl: Aberrant expression of cellular oncogenes in human cells; mdecular overexpression of

carcinogen-metabolizing enzymes.

Charles B. Kasper: Regulation of membrane-bound enzymes responsible for the metabolic activation of chemical carcinogens.

James A Miller: Biochemistry of chemical carcinogenesis, with emphasis on the metabolic activation of chemical carcinogens and their interactions with tissue constituents.

Gerald C. Mueller: Mechanisms of action of estrogenic hormones; studies of cell differentiation in culture; molecular biology of alcohol dependency.

Henry C. Pitot: Regulation of genetic expression in normal and neoplastic liver in viva and in cell culture: quantitative studies in hepatocarcinogenesis; genetic disease mechanisms.

Alan P. Poland: The Ah receptor and tumor promotion; mechanisms of action of halogenated aromatic hydrocarbons.

Applications, including curriculum vitae, description of research interests, and the names of three references, should be directed to individual faculty members at the McArdle Laboratory for Cancer Research, University of Wisconsin-Madiscn, 450 North Randall Avenue, Madison, WI 53706.


Faculty Positions Molecular Biophysics and

Biochemistry Yale University

The Department of Molecular Biophysics and Biochemistry seeks applicants for two positions at the level of assistant professor in the general areas of biophysics, biochemistry, and molecular biology. Qualified applicants would be expected to develop an independent research program and to participate in departmental teaching. Candidates should submit a curriculum vitae with a summary of present and future research interests, and request that three letters of recommendation be sent no later than February 15, 1999 to: Dr. Wflliem McGinnis Chairman, Search Committee Dept of Molecular Biophysics and Biochemistry P.O. Box 6666 260 Whitney Avenue New Haven, CT 06511. Yale is an Equal Opportunity,LAr%matbs Action Employer and particularly encourages applications from wOrnen and minorities.

ASSISTANT/ASSOCIATE PROFESSOR LABORATORY OF TOXICOLOGY

HARVARD SCHOOL OF PUBLIC HEALTH AND DEPARTMENT OF BIOLOGICAL CHEMISTRY

AND MOLECULAR PHARMACOLOGY HARVARD MEDICAL SCHOOL

The Laboratory of Toxicology is searching for a junior faculty member to establish an independent research program on molecular and/or biochemical mechanisms of cellular injury. Research interests should complement those of current faculty which include molecular mechanisms of mutagenesis in bacteria, yeast, and mammalian cells; DNA repair genes; receptor-mediated toxicity; chemical carcinogenesis and tumor promotion; molecular events regulating the mammalian cell cycle; and biochemical and molecular regulation of epithelial cell differentiation. The position includes the opportunity and responsibility for doctoral and postdoctoral teaching and training. Send curriculum vitae, a statement of research interests, and the names of three references to: Prof. Armen H. Tashjian, Jr., Laboratory of Toxicology, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115. Harvard Univer- sity is committed to increasing rrspresentation of minority members and wvmen among its faculty and particularly encourages applications from such candidates.

Tenure Track Position University of Kentucky Medical Center/L.P. Markey Cancer Center

The Departments of Surgery and Microbiology and Immunology invite applications for a tenure track position at the level of assistant/associate professor. Candidates should have a strong background in cell or molecular biology with an interest in the biology of cancer cells. of particular interest are candidates with expertise in the mechanisms of tumor invasion and metastasis, the role of retroviruses in tumor etiology and development, or the role of viral or cellular oncogenes in tumor progression. The applicant will join an active group of cell and molecular biologists located in the recently completed Dorothy Enslow Combs Building of the Lucille Parker Markey Cancer Center. Applicants must hold the Ph.D., M.D., or D.V.M. degree and have at least two years of postdoctoral experience. Associate professor candidates must have an established research program. An attractive start-up package is available and the 12-month salary is competitive and commensurate with experience.

Applicants should submit an application letter, curriculum vitae, a statement of research interests, and send three letters of reference to:

Stephen G. Zlmmer, Ph.D. Chairman, Search Commfttee Department of Microbiology and Immunology LP. Markey Cancer Center 600 Rose Street Lexfngton, KY 406364Wl.

The IJniwrGty of Kentucky is an Affirmative Action/Equal Opportunity Employer.

Cell. Vol. 55, No. 5. December 2, 1988

MOLECULAR AND CELLULAR BIOLOGY PROGRAM (IMCBP) at the UNIVERSITY OF WASHINGTON

invites application to the multidepartmental program in Molecular and Cellular Biology, leading to the Ph.D. degree in the sponsoring departments in the School of Medklne: Biochemistry, Bitengineering, Biological Structure, Immunology, Microbiology, Pathology, Pharmacology and Physiology-Biophysics and in the College of Arts and Sciences: Botany, Genetics and Zoology. Faculty members participating in the IMCBP are located on the University of Washington campus and at the Fred Hutchinson Cancer Research Center.

The University of Washington is a leader in developing technologies used in molecular and cellular biology and in applying these to advance the understanding of basic biological processes. Faculty research interests encompass both prokaryotic and eukaryotic (animal and plant) cells in such research areas as:

Cell Membranes/Ion Channels and Membrane TransporVCell Receptors; Cell Division/Cell Proliferation/Ceil Cycle; Cell Differentiation; Intracellular Organelles; Cytoskeleton/Biomechanics; Cell Transformation/Tumor Bbbgy/Oncogenes/ Oncogenesis; Molecular Genetics/Regulation of Gene; Expression/Growth Factors/Hormones; DNA Replication/Mut- agenesis/Repairand Recombination; Chromosome Structure and Functiin; Gene Structure and Gene Families; Viruses/ Retrovimses; Molecular Structure (MRI/X-ray Crystallography)/Protein Structure

For more information about the IMCBP graduate study or the IMCBP Undergraduate Summer Research Internships PrOgtWII at the University of Washington, send inquiries to: Dr. Karen Holbrook, Director, IMCBP, School of Medicine SC-64, University of Washington, Seattle, WA 98195.

-------------------------------------------------“--------------- Graduate Program Applkations due February 1,1989

Undergraduate 1989 Summer Program Applications due March 1,1989

Postdoctoral Position La Jolla Cancer Research Center

A postdoctoral position is available to study the retinoio acid receptor and other novel members of this nuclear receptor family, their mechanisms of gene regulation, and their role in differentiation and oncogenesis. Competence in DNA technology and tissue culture are desirable.

The La Jolla Dancer Research Foundation is a growing basic research center located in the biomedical research park of San Diego. Please send curriculum vitae with names of three references to:

Dr. Magnus Pfahl La Jolla Cancer Rerearch Foundation 10991 North Torrey Pine8 Road La Jolla, CA 92037.

An Equal Oppotidty,,Affirmat Action Employer.

Postdoctoral Position Transcriptional Regulation in

Drosophila University of California, San Diego

A postdoctoral position is presently available to study RNA polymerase II transcription in Drosophila. The research will involve biochemical analysis of RNA polyrnerase II transcription as well as identification and characterization of factors that regulate the spatial and temporal expression of genes during development of the embryo.

Please send curriculum vitae and at least two letters of reference to:

Dr. James T. Kadonaga Department of Biology, &022 Unlverslty of California, San Dlego La Jolla, CA 92093.

The Uniwsrsity of California is an Equal Opportunity/ Affirmatiw Action Employer.

Cell, Vol. 55, No. 5, December 2,1988

Faculty Positions Department of Biochemistry and Molecular Biology St. Louis University School of Medicine

The E.A. Daisy Department of Biochemistry and Molecular Biology at St. Louis University intends to make two faculty appointments at the junior or senior level to strengthen current expertise in the following areas:

Protein Structure and Function: Individuals with research experience and interest in the mechanisms of enzyme catalysis, protein-protein and/or protein-nucleic acid recognition, and allosteric effects are encouraged to apply for this position.

Cellular Regulation: Individuals with research experience and interest in membrane biochemistry and function, biosynthesis of membrane lipids and carbohydrates, organelle biogenesis, and transport mechanisms are encouraged to apply for this position.

Of particular interest are those applicants who combine classical biochemistry and modern strategies in an innovative independent research program. Successful candidates will complement ongoing research in the areas of metabolism and regulation, molecular and developmental biology, genetics, cell biology, and physical biochemistry and can participate in the multidepartmental Cell and Molecular Biology program at St. Louis University School of Medicine. Excellent start-up funds and salary are available. Curriculum vitae, description of research plans, and at least three letters of recommendation should be sent by February 1, 1989 to: Search Committees c/o Dr. Willlam S. Sly, Chairman, Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, 1402 South Grand Boulevard, St. Louis, M O 63104. St. Louis University is an Equal ~portunity/AfY7rmatiw Action Emphysr.

Research Scientists Gilead Sciences, Inc.

We seek talented, energetic, Ph.D. or postdoctoral level molecular biologists, cell biologists, and cellular virologists who would like to work as a team with other first-rate scientists in developing a novel class of human therapeutics. Qualified scientists will face unparalleled opportunity in a new, well-funded life sciences company.

We are located in the San Francisco Bay Area, offering excellent salary and benefits, including employee stock ownership.

Strict confidentiality is assured.

Please send curriculum vitae to:

Gilead Sciences, Inc. 344 Lakeside Drive Foster City, CA 94404.

Molecular Biologist University of Plttsburgh School of Medicine

The Department of Pathology at the University of Pittsburgh School of Medicine is seeking a molecular biologist with a Ph.D. and postdoctoral training to join its Clinical Molecular Biology Unit at the level of assistant professor. A strong background in cloning and hybridization methods is desirable. Responsibilities will include the application of molecular techniques to the diagnosis of disease and development of an independent research program. Send curriculum vitae and three references to:

Dr. Joseph Locker Associate Director Clinical Molecular Biology Unit c/o A Roman-Keller University of Pittsburgh School of Medicine Department of Pathology 776 !3calfe Hall Pittsburgh, PA 15261.

Cell, Vol. 55. No. 5. December 2,1988

Postdoctoral Molecular Biologist

Albert Einstein College of Medicine

A position is open for a Ph.D. in biochemistry/ molecular biology to study the pathogenesis of viral infections in animals. Minimum two years postdoctoral research training is required which should include experience with glycoproteins, and recombinant DNA including sequencing, site directed mutagenesis, and expression of mutant viral genes in mammalian cells. Familiarity with growth of viruses and the infection of laboratory animals is important. Salary will be $24,OOO/yr. Send resume and three letters of reference to:

Dr. Marshall Horwitz Dept of Microbiology and immunology

Albert Einateln College of Medicine 1200 Morris Park Avenue

Bronx, NY 16461.

An Equal Opporhmity Employer.

Doctoral Studies in Biology and Molecular Biology

University of Maryland Baltimore County

The Department of Biological Sciences of the University of Maryland Baltimore County offers courses of study leading to Ph.D. degrees in Biological Sciences, Molecular and Cell Biology, and Marine Estuarine- Environmental Studies. The research interests of the 25 faculty of the Department include microbiology, molecular biology of prokaryotes and eukaryotes, plant biology, genetics, cell and developmental biology, physiology, ecology, and evolution. The Department is equipped with state-of-the-art facilities for modern research in biology, and is located on the most rapidly growing campus of the University of Maryland system. Graduate assistantships offered to incoming students include a 12 month stipend of $10,325 and remission of tuition. To obtain an application form and further information please write to: Dr. Paul S. Lovett, Chairman, Graduate Programs In Bloiogicai Sciences Department of Biological Sclence8, University of Maryland Baitimore County, 6401 Wfikens Avenue, Baitimore, MD 21226.

Cardiovascular Research Training at the Massachusetts Institute of Technology Program of Excellence in Molecular Biology

Postdoctoral Research Training Fellowships in the Molecular Biology of the Blood Vessel Wall are available for candidates with an M.D. or Ph.D. degree at an NIH-HLB sponsored Program of Excellence in Molecular Biology of the Cardiovascular System. The twin goals of this Program are:

1) to develop an environment in which the most effective strategies of molecular biology will be employed to expand our knowledge of the function and malfunction of the cardiovascular system 2) to train young investigators who will apply basic science approaches to the continued resolution of major unanswered questions in this area.

Our training program is designed to foster extensive interactions between the trainees and senior faculty at MIT as well as at a variety of universities and medical institutions and to prepare these scientists for independent research careers. Research opportunities are available in the laboratories of one or more of the following participating training faculty: Robert Rosenberg (Endothelial Ceil Receptors), Monty Krieger (Genetic Analysis of Acetyl-LDL Receptors & Foam Cells), David Housman (Genetic Predisposition to Cardiovascular Disease), Richard Hynes (Fibrinectin and Cardiovascular Structure/Function), Harvey Lodish (Glucose Transporters), Rudolf Jaenish (Collagen and Cardiovascular Structure/Function), Richard Mulligan (Genetic Therapy of Hyperlipidemia), Earl Ruley (Oncogene Induced Lipogenesis). Interested candidates should send a resume indicating any preferences in possible mentors to: Robert D. Rosenberg, Program Director, Program of Excellence in Molecular Biology of the Cardiovascular System, Marsachusetts institute of Technology, Department of Biology, 77 Massachusettr Avenue, Cambridme. MA 02139. Teleahanet I15171 ?S!LAAfid.

cell. vol. 55. No. 5, December 2, 1988

Postdoctoral Fellow Stanford University School of Medicine

Seeking postdoctoral fellow to work on studies involving the regulation and expression of neurotransmitter synthetic enzymes. Experience in molecular biology and biochemistry essential. Experience in tissue culture desirable. Projects focus on genomic transcriptional and translational regulation of neurotransmitter enzymes in vivD and in vitro. Funding is available immediately.

Send a copy of curriculum vitae and three letters of reference to:

Dr. Dona Lee Wong Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine Stanford, CA 94895.

Stanhd is an Egual Opportunity/Affirmathw Action Employer. Minority and bwmen candidates an? encouraged to apply.

POSTDOCTORAL POSITION

University of Southern California

A postdoctoral position is immediately available for molecular studies in neurobiology of aging. Funded studies include genomic responses in the hippocampus to Alzheimer’s Disease and to stress: see Neuroscience Society Abstracts 74: abstracts Xl 1, 12, 361.1, and 361.11 (1988).

Send curriculum vitae and names of three references to:

Caleb E. Finch, Ph.D. USC Gerontology Center 3715 McCllntock Avenue

Los Angeles, California 98989-8191.

Graduate Student and Postdoctoral Fellowships in Environmental Molecular and Cellular Carclnogenesis and Mutagenesis

University of Cincinnati College of Medicine

The University of Cincinnati College of Medicine offers a modern interdepartmental training program in environmental molecular and cellular carcinogenesis and mutagenesis. Cincinnati is a leading academic and industrial center for environmental studies providing numerous employment opportunities. Experimental approaches within the program include the role of growth factors and oncogenes in cellular transformation, the use of transgenio cells and animals, and molecular toxicology. Participating faculty are: Dr. Roy Albert (carcinogenic mechanisms and risk assessment); Dr. Stuart Baxter (tumor promotion); Dr. Michael Lleberman (growth factors and differentiation); Dr. John Loper (P45g systems in yeast); Dr. Steven Potter (insertional mutagenesis in transgenic mice); Dr. Howard Shertzer (chemoprevention of carcinogenesis); Dr. Peter Stambrook (mutagenesis in transgenic cells and mice); Dr. Edward Stavnezer (oncogenes and cell transformation); Dr. James Stringer (recombination and gene targeting in ES cells); and Dr. David Warshawsky (mechanisms of chemical carcinogenesis).

Positions are immediately available and are funded through a national research training program. Applicants must have U.S. citizenship or permanent residency and have completed a Ph.D. degree or equivalent. Candidates should send curriculum vitae and three letters of recommendation to:

Dr. Peter J. Stambrook, Department of Anatomy and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45987.

An Equal Oppottunily/A@irmat Action Employer.

Cell. Vol. 55, No. 5. December 2. 1988

EMBRYOGEN

Embryogen is an advanced biotechnology company whose major focus is in transgenic animal technology. Embryogen is developing animal models of human diseases, new approaches to molecular farming and genetic engineering of farm animals.

Openings are available in our new Molecular Biology Center in Princeton, N.J. and our Animal Sciences Center in Athens, Ohio. Both locations offer close working relationships with academic laboratories and excellent living environments. Available Senior Positions are in three Divisions:

1. Molecular Biology, Director and Senior Scientists.

2. Gene and Protein Engineering, Director and Senior Scientists.

3. Animal Sciences, Associate Director and Senior Scientists.

In addition, positions are available at the MS and BS level for experienced lab supervisors and technicians.

All senior candidates will have several years of relevant postdoctoral research experience and a proven track record. Experience in Recombinant DNA Technology, Molecular Genetics, Protein Chemistry, Pathology, Physiology, Embryology or Gene Transfer is required. Please send your curriculum vitae with a list of publications and the names of three references to:

Steven H. Hoitzman, 1 President St., Athens, OH 45701-2979.

Postdoctoral Position Harvard Medical School Molecular Biology of

Growth Factor Signals

Applications are invited from candidates with (projected) Ph.D. or M.D. degree who are interested in studying the molecular mechanism of growth factor receptor signal transmission in mammalian cells and yeast (see Nature 324: 6&70 [ 19861, Science 236: 197- 200 [lQ87], and PNAS 85: 1477-1481 [lQ88]). Candi- dates with expertise in recombinant DNA teChnOlogy, mammalian cell biology, protein chemistry, or yeast biology are especially encouraged to apply. Please send curriculum vitae, a 1-2 page summary of your scientific background, reprints, reprints or abstracts (where available), and the names of three references or call: Dr. Helmo Reidel Section of Molecular Biology Joslin Diabetes Center 1 Jorlin Place Boston, MA 02215 (617) 732-2691.

Faculty Position Eukaryotic Molecular Genetics Illinois State University

The Department of Biological Sciences at Illinois State University seeks applicants for a tenure track appointment at the assistant or associate professor level. Applicants using molecular techniques to study gene regulation and/or development are preferred, and should have demonstrated research potential through postdoctoral experience and recent publications. The successful candidate will be expected to maintain an independent, extramurally funded research program, and to participate in the training of MS. and Ph.D. candidates. Teaching responsibilities will include a graduate course in the candidate’s specialty and involvement in the undergraduate program. Applicants should send their curriculum vitae, a brief description of future research plans, and the names, addresses, and telephone numbers of three references by January 6, 1989 to: Dr. David Borst, Department of BIologIcal Sciences, Illlnols State University, Normal, IL 61761. Illinois State Uniwsity is an Equal Opportunity/ Affirmaf/ve Action Employs.

Cd, Vol. 55, No. 5, December 2,19&3

Postdoctoral Positions Department of Agriculture (USDA) Agricultural Research Service

ARS has openings for two research biologists/genet- icists. One position will investigate the effect of high temperatures on the synthesis of wheat endosperm storage proteins. The other position will study storage protein mRNA transport from the nucleus to the cytoplasm in the developing wheat endosperm cell. Candidates for the first position should have experience with the use of radioisotopes, mRNA isolation, and western blotting. In vitro translation and in situ hybridization experience would be useful. Candidates for the second position should have experience in mFiNA isolation and microinjection techniques. Salary will be commensurate with experience ($27,716 to $88,218 per annum). For information on the research program contact Dr. John E. Bernardin (415)559-5761 Applications in response to this advertisement should be marked 9W9W. Applications must be received by December 15, 1988. Mailing address: Dr. John E. Bernardin, Western Regional Research Center, 800 Buchanan Street, Albany, CA 94710. An Equal Opportunity Employtv.

Postdoctoral Research Position I

Molecular Mechanisms of Mammalian Cell Growth Control

Mayo Clinic/Mayo Foundation I

A postdoctoral position is available January 1, 1989 to study the molecular and cellular biology of peptide growth factors. Specific areas of research include the identification and cloning of growth factor-regulated genes and the delineation of specific protein-DNA interactions involved in transcriptional control. Applicants should possess a strong background in one or more of the following areas: recombinant DNA methodology; protein biochemistry; mammalian cell culture techniques. Send curriculum vitae and three references to:

Dr. Michael J. Getz Department of Bkchemiatry and Molecular Biology Mayo Clink/Mayo Foundation Rochester, MN 55905.

An Equal Opportunity/Afirmatiw Action hMtution. 1

Assistant Professor of Biochemistry North Dakota State University

Two tenure track positions are available in the Depart- ment of Biochemistry, North Dakota State University. Ph.D. in biochemistry/chemistry and postdoctoral experience required. Ability to communicate clearly is essential. Candidates with research interests in physical biochemistry, protein/membrane structure, enzymology, or cell/developmental biology are encouraged to apply. Successful candidates are expected to develop a strong independent research program with potential for grant support and participate in teaching of graduate and undergraduate students. Send curriculum vitae, transcripts, a brief description of current and future research interests, and three letters of reference to: Dr. Arland E. Oleson Search Committee Department of Biochemistry North Dakota State University Fargo, ND 69105. Available July 1, 1989; closing date is February 1, 1989. An Equal Oppottunity/Afirmatiw Action Employer.

Assistant Professor University of California, San Francisco

The Lung Biology Center at the University of California, San Francisco, is seeking a cell and molecular biologist to lead an independent research program examining the molecular biology of cell surface adhesion, with special reference to molecules potentially relevant to lung injury and repair. This faculty member will also be expected to take part in the regular teaching activities of the departments of Medicine and Pharmacology. Candidates must have a Ph.D. degree, and at least four years of postdoctoral research experience in adhesion receptor biology. The annual salary will be $50,900 - 80,000 depending upon experience. Please send resume and the names and addresses of four references to: Dean Sheppard, Dlrector, Lung Biology Center, Bldg. 1, Rm. 1 SO, San Francisco General Hospltal, 1001 Potrero Avenue, San Francisco, CA 94110. Deadline for receipt of application is l/10/89. The University of California, San Francisco, is an Equal Opportunify/ARrmative Action Employer. Women and minorfrIes ant encouraged to apply.

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