Cell, Vol. 57, No. 7. June 30,1989 Positions Available Cell Classified Information Cell publishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $225 for a quarter page, $425 for a half page, and $795 for a full page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next available issues are as follows (all material due close of business on due date): dug. 11,1989 issue: copy due July 7,1989 *Aug. 251989 issue: copy due July 21,1989 *Sept. 8,1989 issue: copy due Aug. 4,1989 &ept. 22,1989 issue: copy due Aug. IS,1989 &ct. 20,1989 issue: copy due Sept. 151989 *Nov. 3,1989 issue: copy due Sept. 29,1989 *Nov. 17,1989 issue: copy due Oct. 13,1989 l Dec. 1,1989 issue: copy due Oct. 27,1989 eDso. 22,1989 Issue: copy due Nov. 17,1989 Advertisements should be sent to: CLAUDIA BAEZA Classified Ad Department Cdl 60 Church Street Cambridge, MA 02138 (617-661-7059) FAX Number (617-661-7061). Postdoctoral Position Molecular Immunogenetics Massachusetts General Hospital A position is available for ongoing work related to analysis of mechanisms of genetic susceptibility to autoimmune CNS disorders including multiple sclerosis. Experience in human immunology or in molecular biology desirable. Applicants should possess a Ph. D. or equivalent and have a record of scientific accomplishment. Position is for three years; salary competitive. Please send curriculum vitae and names of three references to: Stephen L. Hauser, M. D. Neuroimmunology Unit Warren 352 Massachusetts General Hospital Fruit Street Boston, MA 02114. Postdoctoral Fellowships M. D. Anderson Cancer Research Center University of Texas We are looking for outstanding, highly-motivated and knowledgeable individuals interested in basic fundamental research in the area of cytokines. The focus of our laboratory is on the identification of novel cytokines (growth inhibitors and stimulators) produced by tumor cells and by the cells of the immune system and involved in tumor cell-surveillance. We are also looking for individuals interested in understanding the role of oncogenes, slgnal-transductior and growth factors in the mechanism of tumor ceil resistance to these cytokines. Applicants with a Ph. D. degree should have an experience in one or more of the following areas: cell biology, protein purification and cDNA cloning. Background in area of cellular immunology and/or tumor biology is desirable but not necessary. Please send curricula vitae and names of three references to: Dr. Bharat B. Aggarwal, Chlef of the Cytokine Research Section, CIBT/Box 41, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030. Equal Opportuniiy/Affrmat Action Employer.
Cell, Vol. 57, No. 7. June 30,1989
Cell C lassified Information Cell publishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $225 for a quarter page, $425 for a half page, and $795 for a full page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next available issues are as follows (all material due close of business on due date):
dug. 11,1989 issue: copy due July 7,1989 *Aug. 251989 issue: copy due July 21,1989 *Sept. 8,1989 issue: copy due Aug. 4,1989 &ept. 22,1989 issue: copy due Aug. IS,1989
&ct. 20,1989 issue: copy due Sept. 151989 *Nov. 3,1989 issue: copy due Sept. 29,1989 *Nov. 17,1989 issue: copy due Oct. 13,1989 l Dec. 1,1989 issue: copy due Oct. 27,1989 eDso. 22,1989 Issue: copy due Nov. 17,1989
Advertisements should be sent to: CLAUDIA BAEZA
Classified Ad Department Cdl
60 Church Street Cambridge, M A 02138 (617-661-7059)
FAX Number (617-661-7061).
Postdoctoral Position Molecular Immunogenetics Massachusetts General Hospital
A position is available for ongoing work related to analysis of mechanisms of genetic susceptibility to autoimmune CNS disorders including multiple sclerosis. Experience in human immunology or in molecular biology desirable.
Applicants should possess a Ph. D. or equivalent and have a record of scientific accomplishment. Position is for three years; salary competitive.
Please send curriculum vitae and names of three references to:
Stephen L. Hauser, M. D. Neuroimmunology Unit Warren 352 Massachusetts General Hospital Fruit Street Boston, M A 02114.
Postdoctoral Fellowships M . D. Anderson Cancer Research Center University of Texas We are looking for outstanding, highly-motivated and knowledgeable individuals interested in basic fundamental research in the area of cytokines. The focus of our laboratory is on the identification of novel cytokines (growth inhibitors and stimulators) produced by tumor cells and by the cells of the immune system and involved in tumor cell-surveillance. We are also looking for individuals interested in understanding the role of oncogenes, slgnal-transductior and growth factors in the mechanism of tumor ceil resistance to these cytokines. Applicants with a Ph. D. degree should have an experience in one or more of the following areas: cell biology, protein purification and cDNA cloning. Background in area of cellular immunology and/or tumor biology is desirable but not necessary. Please send curricula vitae and names of three references to: Dr. Bharat B. Aggarwal, Chlef of the Cytokine Research Section, CIBT/Box 41, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030. Equal Opportuniiy/Affrmat Action Employer.
Cell, Vol. 57. No. 7, June 30, 1989
Assistant Professor Department of Cancer Biology Harvard School of Public Health The Department of Cancer Biology is seeking applications for a position of assistant professor in the Laboratory of Radiobiology. Candidates should have training in molecular genetic technology, and an interest in pursuing research in molecular carcinogenesis and/or radiobiology. The successful candidate will be expected to develop a strong research program and assume limited teaching responsibilities including supervision of doctoral students. A doctoral degree with two to three years of postdoctoral research experience is required, with demonstrated evidence of innovative research capability. Send curriculum vitae with a complete bibliography, representative reprints, description of research interests, and the names and addresses of three references to: Dr. John B. Little, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02116. Harvatd University is committed to increasing representation of women and minority members among its faculty and particularly encourages applications from such candidates.
Postdoctoral Position Molecular Biology of Human Granulocytes Beth Israel Hospital Harvard Medical School
Grant funded position available immediately for new Ph. D. or more senior associate, preferably with experience In protein chemistry/cell biology, gene cloning and sequencing. Research involves the cloning, regulation of expression, and structure-function relationships of granule proteins of human eosinophilic and basophilic leukocytes. Send curriculum vitae and three letters of reference to:
Dr. Steven J. Ackerman Department of Medicine Beth Israel Hospital 330 Brookline Avenue Boston, MA 02215.
Biochemist, Molecular, and Biomechanicai Engineers Department of Orthopaedic Surgery
University of Pittsburgh School of Medicine
The Department of Orthopaedic Surgery is currently seeking biochemist, molecular biologist, and biomechanical engineers at the Assistant, Associate, and full Professor levels. These are tenure track positions with secondary appointments either in Engineering or the Departments of Microbiology, Biochemistry, and Molecular Biology.
Successful applicants at the junior level will be expected to pursue independent research within the Ferguson Laboratory for Orthopaedic Research in the Department of Orthopaedio Surgery. Senior level candidates should have a track record of original research in biochemistry and molecular biology. Preference will be given to candidates interested in animal models of osteoarthritis and biochemical changes that occur in the carti laginous matrix during osteoarthritis. lt is also expected that successful candidates will participate in the Department’s teaching program. Each candidate should have a Ph. D. degree and suitable postdoctoral experience.
Interested candidates should send their curriculum vitae and three letters of recommendation to: James H. Herndon, M. D. Professor and Chairman
Department of Orthopaedic Surgery University of Pittsburgh School of Medicine
Room M272 Scalfe Hall Pittsburgh, PA 15261.
The University of Pittsburgh School of Medicine is an Equal Opportunity and AiCmative Action Employer. Women and minorities are encouraged to apply.
Cell, Vol. 57. No. 7. June 30,1989
1 IMMUNOLOGY POSTDOCTORAL FELLOWSHIPS i . 2 ‘% , 2’ Memorial Sloan-Kettering Cancer Center
‘*L,I.ID \’ Postdoctoral fellowships, supported by an NCI National Research Service Award, are available immediately within the Immunology Program at Momorlal SloaneKoBorln# Cancer Cantor. The main research areas of the Faculty cover the biolopicsl, blochemlssl and molecular aspects of immuno#onatlcs, cellular lmmunolopy and tumor lmmunolo#y.
Anthony t! Albino - Gncogenes in pathogenesis of melanoma; in vitro transformation of normal cells &I Uupont - Genetic, molecular and biological aspects of the MHC in humans Noal Flomonber# - Activation, function and regulation of human T and B cells Ulrlch ttammsrling - Immunogenetics of murine and human cell surface antigens: special emphasis on T cell activation Alan Hounhbn - Differentiation and transformation-related an- tigens of human cancer Robert Knowles - Serological, biochemical and genetic character&ion of human lymphocyte cell surface molecules Janot be - Analysis of structure, function and regulation of human MHC genes Konnoth Ueyd - Biochemical analysis of Qlycoproteins and Qfycolipids of human tumor cells
Hsrborl Oott#en - Humoral and cellular immune responses to human cancer and development of biological approaches to cancer therapy UN Old - Cell surface antigens of mouse and human cancers and development of immunological approaches to the therapy of human cancer Richard 0’Rallly - Siology of allogeneic bone marrow transplan- tation in humans and primates; cellular interactions in engraft- ment, graft-host tolerance and effective immune reconstitution WoU#an# Rottl# - Immunogenetics of differentiation and malig- nant transformation in human tumors Bl/an Batal - Studies of epidermal keratinocytes and Langerhans cells and lymphocyte-epidermal cell interaction Oslas Stutman - Development and maintenance of functional T cells in mice; role of T and non-T cells in tumor-host interactions Soo YeunQ Ysn# - Gene organization and regulation of gene ex- pression in human class I MHYC region
Curriculum vitae, statement of research experience and future goals, and names of three references should be sent to: Konnoth 0. Lloyd, Ph.D., Chairman, Immunology Pro#ram, Memorial Sloan-Kottorln# Cancer Center, 1275 York Avonua, Naw York, NY 1tWl. MSKCC is committed to equal opportunity through affirmative action and therefore, members of minority groups are encouraged to apply.
Postdoctoral Positions Cancer Biology Research Laboratories Queen’s University
Positions are available in an expanding multidisciplinary group for individuals with research backgrounds in molecular biology and protein chemistry Research topics include studies on: protein/DNA interactions involved in developmental and hormonal regulation of gene expression; cellular and molecular mechanisms involved in tumor progression; and acquisition of multi drug resistance. Excellent laboratory and technical service facilities are available.
Interested applicants should provide a brief description of previous research experience, a curriculum vitae and the addresses of three references to:
Dr. R.G. Deeley, Dlrector Cancer Biology Research Laboratories Botterell Hall Queen’s University Kingston, Ontarlo Canada, K7L 3N6
Postdoctoral Position Molecular Biology of Photosynthesis Louisiana State University At least one postdoctoral position is anticipated to become available after September 1 to study the structural and functional effects of mutagenesis within the large extrinsic loop region of CPa-1 (CP47) in the cyanobacterium Synecbocystis 6803. This project will entail the production of mutants by saturation and oligonucleotidedirected mutagenesis, screening for photoheterotrophic growth and temperature-sensitive phenotypes, DNA sequencing, and characterization of the photosynthetic properties of the isolated mutants. Experience with standard molecular procedures (DNA isolation, restriction enzyme analysis, DNA sequencing) is highly desirable. Initial appointment is for one year with reappointment depending on performance. Applicants should send a curriculum vitae and names of three reference to: Dr. Terry M. Brlcker Department of Botany Loulslana State University Baton Rouge, LA 70803. LSLJ is an Equal Opportunity/AtTrmative Action Employer.
Cell. Vol. 57, No. 7, June 30.1989
Postdoctoral Position Cellular Biology University of Virginia
A fully funded postdoctoral research position is available immediately to study the biochemical basis for membrane trafficking between intracellular organelles of the eukaryotic cell. The research program focuses on lipid metabolism, pathways for uptake from the plasma membrane, and epithelial cell polarity with particular emphasis on glycosphingolipids. Experience in tissue culture, subcellular fractionation, and techniques of lipid characterization desirable.
Applicants should send their inquiries, curriculum vitae, and the names/phone numbers of three references to:
Dr. William W. Young, Jr. Department of Pathology University of Virglnla Health Sciences Center Charlottesville, VA 22908.
An Equal Oppottunity/Wirmative Action Employer.
Two Assistant Professors Gene Expression/Molecular Structure
The University of Texas at Dallas
The Molecular and Cell Biology Program of the University of Texas at Dallas invites applications for two tenure track positions at the assistant professor level beginning no later than September 1, 1990. Applicants should have at least two years of postdoctoral experience and show evidence of the development of a vigorous and independent research program with the capability of obtaining external support. Candidates should be actively engaged in research in the broad areas of either (1) structural molecular biology or (2) the biochemistry or genetics of gene expression (eukaryotic or prokaryotic), which could include, for example, the molecular biology of development. Applicants must be qualified to teach part of a graduate core course in molecular biology or cell biology or in macromolecular physical chemistry. The Molecular and Cell Biology Program is well equipped and currently has 13 faculty and 43 graduate students, almost all of whom are Ph. D. candidates. Send curriculum vitae (identification of sex and ethnicity for Affirmative Action statistical purposes is requested but not required), a short description of research plans, and names of three or more references to:
Academic Search Number 291 The University of Texas at Dallas
P. 0. Box 830888 Richardson, TX 75083-0888.
Applications should be received by August 31, 1999.
The Univwsity of Texas at Dallas is an Affirmative Action/Equal Opportunifv Employer.
Cell, Vol. !V. No. 7, June 30.1989
Molecular Geneticist Berman-Gund Laboratory Harvard Medical School
Position available in the Berman-Gund Laboratory, Harvard Medical School. To apply recombinant DNA techniques to the study of hereditary retinal degenerations. Ph. D. and two years postdoctoral fellowship required. Background in molecular biology and interest in gene expression preferred. Experience with expression vectors desirable. Harvard tenure track appointment commensurate with experience. Send curriculum vitae and names of three references to:
Dr. Eliot L Berson, Director Berman-Gund Laboratory Massachusetts Eye & Ear lnflrmary 243 Charles Street Boston, MA 02114.
ST JOHN’S UNIVERSITY New York
Department of Biological Sciences Postdoctoral Research Associate - A position is available immediately to study signal transduction in Aspergillus nidulans. The research will involve cloning and disruption of the gene for a calmodulin-dependent pro- tein kinase (Proc. Nat. Acad. Sci. 85, 3279). Experience in molecular and microbiological research is desirable. Salary and benefits are competitive. Please send a curriculum vitae and names of three references to: Dr. Diana Barteit, Department of Biological Sciences, St. John’s University, Grand Central & Utopia Parkways, Jamaica, NY 11439. St. John’s University is an equal opportunity employer-M/F.
Director of Pediatric Endocrinology Department of Pediatrics
University of Minnesota Medical School Minneapolis, Minnesota
The University of Minnesota, Department of Pediatrics is seeking a Director of the Division of Endocrinology. This is a senior position and has high priority in the Department of Pediatrics and the Medical School. The candidate should have leadership, clinical and research experiences necessary to direct an Endocrinology and Metabolism Program in a strong academically oriented department.
Qualifications: Candidate must have an M. D. degree or equivalent. This position will be a Tenured/Associate or Full Professor with the rank to be commensurate with the years of experience and aocomplishments. The candidate must have demonstrated professional distinction in research and writing, have an active ongoing research program which has attracted national funding, and have demonstrated effectiveness in teaching and advising. Candidate must be approved by the Promotions Committee of the Department of Pediatrics and the Medical School.
Last date for receipt of application is July 31,1989 with the earliest start date being January 2, 1990. Applications and nominations, (include names and addresses of three referees), should be sent to:
S. Michael Mauer, M. D. Chairman, Search Committee for Head of Pediatric Endocrinology and Metabolism
University of Minnesota Medical School Box 491 Delaware S. E.
Minneapolis, MN 55455. The University of Minnesota is an Equal Opportunity educator and employer and specifiially invites and encourages applications.
Cell, Vol. 57, No. 7, June 30,1989
Molecular Viral Pathogenesis
National Institute of Neurological Disorders and Stroke
National Institutes of Health Public Health Service
Applications are invited from scientists having a Ph. D. and/or M.D. degree and at least 6 years of postdoctoral experience to lead an NIH intramural research section studying the molecular basis of intracellular host factors controlling viral infections in animal models and humans, and to head a transgenic mouse facility serving the needs for transgenics of several laboratories. The position requires that the incumbent have expertise and creativity in the planning and performance of complex research projects, requiring a multidisciplinary approach, and for training of section personnel. The incumbent must satisfy the following specific requirements: Proven ability to produce creative research in cellular and molecular analysis of host gene control of viral infections with emphasis on viral gene expression, replication and assembly; Experience in molecular and cellular virology, cell culture, cell microinjection techniques, production, purification and use of peptide specific antibodies, and recombinant DNA techniques including eukaryotic expression systems; Experience in animal viral pathogenesis, and the design, production and analysis of transgenics; Experience with antivirals such as interferon; Thorough interest in transcription factors regulating viral and host genes; Familiarity with human viral diseases. A medical background is highly desirable for a wider perspective of basic research that could lead to clinical applications. The position is located in Bethesda, Maryland at the general schedule (tenured) level with a salary of $41,121 to $48,592 per annum depending on experience and qualifications. For further information please contact Mrs. Christine M. Steyer at (301) 496-6334. Please send curriculum vitae, a detailed description of your past activities and future research plans and three letters of recommendation to:
Mrs. Christine M. Steyer National Institute of Neurological Disorders and Stroke &- IN+4 National Institutes of Health $ Building 31, Room 8A23 z (k\ 3 9000 Rockville Pike “/.& Bethesda, Maryland 20892 (U.S.A.)
NIH IS AN EQUAL OPPORTUNITY EMPLOYER
Faculty Positions Molecular Biology, Biochemistry, Cell Biology The Department of Dermatology at Case Western Reserve University and University Hospitals of Cleveland has established the Skin Diseases Research Center. To build a leading center for research and education in skin diseases, we are developing our research programs, recruiting new faculty and expanding facilities. We expect individuals will obtain joint appointments in basic science departments as part of the Center’s interdisciplinary approach to biomedical research. Several junior and senior tenure-track faculty positions are available for Ph. D.s or M. D.s with strong biomedical research programs in molecular biology, biochemistry, and/or cell biology as applied to the skin. Special expertise in protein structure/function, immunodermatology, photobiology and carcinogenesis is desirable. Submit curriculum vitae, statement of research interests, names of three references, and selected reprints to: David R. Bickers, M. D., Director, Skin Diseases Research Center, Case Western Reserve University, 2074 Ablngton Road, Cleveland, OH 44106. CWRU is an Equal Opportunity/%%mative Action Employer.
Chief Executive Officer V. P. Research and Development
MDSI develops medical diagnostics and therapeutics using recombinant DNA technology and monoclonal antibodies. Current projects include diagnostic tests for Epstein-Barr Virus infections and assays for Hepatitis B Virus. Candidates should have a Ph. D. and five plus years experience as a Principal Investigator of an NIH grant with expertise in cloning and expression of foreign genes, protein purification, immunological assays, and monoclonal antibody development.
Send resume and list of references to: President Molecular Diagnostic Systems, Inc. Department of Biochemistry Johns Hopkins University School of Hygiene 615 North Wolfe Street Baltimore, MD 21205.
Equal Opportunity Employer.
Cell, Vol. 57, No. 7, June 30,198Q
Postdoctoral Positions Department of Biochemistry
SUNY at Stony Brook
The Department of Bioohemisby, State University of New York at Stony Brook has postdoctoral positions available in the laboratories of the foHawlng faculty members.
Dr. Will lamL~nnarz: Mechanism of assembly of glycoproteins. Structure and function of glycoproteins in cell differentiation and embryonic development. Dr. Kenneth Marcu: Transcriptional control of the murine o-myc protooncogene by cis-acting positive and negative elements and their associated nuclear regulatory factors; biological properties of the mylc gene product. Dr. Jakob Schmldh Regulation of acetylcholine receptor subunit expression during development and in response to plasma membrane activity. Dr. Sanford Slmon: Cell biology/biochemistry of inflammatory processes, e.g. inflammatory cell activation, degradation of extracellular matrix and oytokines. Dr. Rolf Sternglanr: DNA topoisomerases and their roles in DNA replication, transcription and recombination, Histone acetylation and its role in chromatic structure and gene expression. Send curriculum vitae and three letters of references to:
Drs. Lennarz, Marcu, Schmidt, Slmon or Sternglanz Department of Blochemlstry
State Unlvershy of New York at Stony Brook Stony Brook, New York 11794-521s by 15 August 1989.
State University of New York at stony Book is an Affirmative Action/Equal Opportunity Educator and Employs-,
Postdoctoral Position Cell Biology University of California, San Francisco
Positions available to study the platelet cytoskeleton or role of lipoproteins in lipid metabolism. Experience with light and electron microscopy required. Send curriculum vitae and three references to:
Personnel Gladstone Foundation Laboratories University of California, San Francisco P. 0. Box 40606 San Francisco, CA 94149-0606.
Senior scientist responsible for scientific leadership of a group involved in the identification and characterization of the gene defect in Huntington‘s Disease. Duties involve RFLP analysis, development of new genetic markers, and identification of candidate genes using techniques in molecular and cell biology including cell culture and animal based gene expression systems. Minimum requirements include a Ph. D. in medical biophysics, or cellular or molecular biology, together with at least three years of postdoctoral experience in the area of mammalian gene regulation. Also required Is demonstrated expertise with recombinant DNA techniques (cDNA and genomic DNA cloning, construction of expression vectors, DNA sequencing, Sl analysis, Northern and Southern analysis) and cell culture techniques (specifically gene transfer) as evidenced by publications or research. Salary range Is $3QooO to $4o,ooO per year. Qualified applicants only respond with resume to: J. 0. # 9607, Massachusetts Department of Employment and Training, Special Programs Department, 19 Stanlford Street, Boston, MA 02114.
Cell, Vol. 57, No. 7, June 30, l=
Junior Faculty Department of Pathology and Laboratory Medicine University of Pennsylvania
Due to cont inued expansion, the Department of Pathology and Laboratory Medicine has vacancies for junior faculty in several areas of laboratory medicine including coagulat ion, hematology, Immunology, microbiology, and toxicology. Candidates should have I commitment to a research oriented career and possess M. D. or M. D./Ph. D. degrees and should be Board eligible or certified in clinical pathology. An Interest in basic science is particularly desirable. Applications with curriculum vitae and names of three references should be sent to:
Dr. D. S. Young, Department of Pathology and l&oratory Medicine, Hospital of the Univerrity of Pennsylvanla, 3400 Spruce Street, Philadelphia, PA 19104-4263.
The Unhwsily of Pennsylvania is an Equal Opportuni ly/~~a~ Action Employer; women and minodty candidates am encouraged to apply.
Postdoctoral Position Department of Biochemistry University of Louisville School of Medicine A postdoctoral posit ion to start 1 September 1gSg is available to study the regulat ion of alcohol dehydrogenase (ADH) genes in Dmsophi la. Utilizing an approach involving the introduction of foreign genes into the germ line of D. me/anogaster and the product ion of gene fusions, we have localized sequence: involved in differential t issue-specific expression of various ADH genes. The present focus is in analyzing the frans-actlng regulatory components that interact with these regions. The long term goal is the elucidation of the mechanisms underly ing tissue-specific regulat ion of this class of complexly regulated genes. Salary is at current NIH approved level. Some exper ience in molecular biology or biochemistry required. Send vitae, summary of research background and interests, and the names and addresses of three references to: Mark Brennan, Department of Blochemlstry, University of Louisvil le School of Medicine, Health Sciences Center, Louisville, KY 40292.
Tenure Track Faculty Position Medical Genetics/Molecular Biochemistry Northwest Center for Medical Education Indiana University School of Medicine The Northwest Center for Medicel Education, Indiana University School of Medicine, seeks appl icants for a faculty posit ion in the areas of biochemistry, molecular biology, and biochemical genetics. Exper ience beyond the Ph. D./M. D. is required. Successful appl icant will be expected to participate in providing services in an establ ished Medical Genet ics Clinic and Cytogenet ics Laboratory and establish a strong independent research program in the area of specialty. Candidates should submit a curriculum vitae and request that three letters of recommendat ion be sent to: Dr. P. G. latrldis Assistant Dean and Director Northwest Center for Medical Educat ion Indiana University School of Medicine 3400 Broadway Gary, IN 46406. Indiana University is an Equal Oppcttunity/Affimat Action Employx.
I Genetics Institute is a company known for its innovative ap- pmach to the scientific research, development and maoufac-
tore of human therapeutic agents. including fibrinolytic and :,:~.~,,; clotting factors, bone morphogenic factors and :,.,;:,, : ..::.. hematopoietic growth factors. The successful application of .,.: .2 a sound business strategy in the development of our corn- ::: ’ patty enhances our strength and promising future in biotech- ” ‘1 nology. g. ,:
Research Associates . ..j.. Several openings exist to join our Molecular and Cellular i$; Genetics and Fibrinolysis Groups. These positions would be r:.$: responsible for the characterization of cell lines. Ideal can- didates will have a BS/MS in the life sciences and solid cell
culture and tissue culture experience.
Molecular Immunology/ .I.....:
/ . . . ,:.. : Mamma lian Gene Expression 1, :;i We are actively recruiting for an individual to join our dis- covery research group studying native and recombinant im-
: i <. ‘:
mttnoglobins intended for therapeutic purposes. The ideal .: candidate will have a ES/MS in the life sciences and experi- ence in mammal ian cell expression. protein characterization
and immunological assay development. A background in !$
recombinant DNA is also beneficial but not a prerequisite :.;. “: ,:
for the position.
We offer a stimulating and dynamic work environment plus ‘.: an excellent salary and comprehensive benefits package. . . . ;
An Equal Opportunity Employer M/F/HIV
Cell. Vol. 57, No. 7, June 30.1989
Assistant Professor of Molecular Biology Department of Environmental Science and Physiology Harvard University Applications are invited from individuals with expertise in molecular biology and protein chemistry and a potential interest in respiratory biology, especially macrophage biology or fibrogenesis. Competence and publications required in some of the following areas: recombinant DNA technology, DNA probe hybridization, regulation of gene expression, isolation and characterization of proteins and peptides. Responsibilities include teaching, but research predominates. Requirements: Doctorate and two to three years experience. Send resume and names of three references to: Dr. Joseph D. Brain Respiratory Blology Program Department of Environmental Science and Physiolog] Harvard School of Public Health 666 Huntington Avenue Boston, MA 02116. Women and minority candidates am particularly invited.
Postdoctoral Position RNA Editing Seattle Biomedical Research lnsitute
A postdoctoral position is available to study RNA editing, a process that changes the nucleotide sequence of mRNA by the addition and removal of nucleotides; see Cell 53: 401,53:4X3 & 55: 267,1988. The research will concentrate on elucidating the molecular basis of this recently discovered posttranscriptional genetic regulatory process, including characterization of the catalytic machinery. Send curriculum vitae, three letters of recommendation and a brief statement of research interests to:
Dr. Kenneth Stuart Seattle Biomedical Research Institute and University of Washington 4 Nickerson Street Seattle, WA 961091651. (206) 264-6646
Equal Oppottunify Employer.
?kRC Funded AIDS project’ Beckenham, Kent
Wellcome is to receive financial support from the MRC for HlV research. This has resulted in the following PhD and graduate level appointments-
sckdst - virology b14,ooo-E17ooo You will study the molecular biology of simian immune deficiency virus with a view to designing novel prophylactic
and chemotherapeutic approaches to the treatment of simian AIDS as a model system for the human disease. Suitable applicants would be expected to have considerable experience in bacterial and eukaryotic expression sys-
tems and some knowledge of molecular immunology would be useful though not essential.
sdenw - Immuno~ology E14,ooo-E17ooQ Located in the Department of Experimental Immunobiology, your main objective will be to carry out research into the
control of the immune response to genetically-engineered HIV antigens by immunological adjuvants. The candidate should have a PhD in Immunology/Virology/Biochemistry, Previous experience in HlV research is
Senior T&h - ImmunobioIogy c.aoJoo Researching adjuvants for HlV antigens, you will be required to carry out a variety of immunological assays, and to
prepare synthetic peptide antigens. Applicants should have a degree in a biological subject.
All of the above appointments will be of a maximum duration of 3 years (current period of funding) and will qualify for Wellcome’s standard terms and conditions of employment. This will include 25 days’ holiday, protit sharing, pension scheme, first class sports and social facilities and subsidised restaurant.
Pl6?WMU?fit4!Withfd career detaila to, Andrew W&l~t. Persona el txfice, The wdcome Rd Labocstortes. Lengley Court, Beckenham, Kent BR3 3B5, quoting retbence 9l/S4. . AwddludalnE4~1~ . Novelthaqudic~dv8ah1u 0 BtablfshedInlS82 . A mbddly ofthe Welkome Founddon L3d.
bd OPF-mdQ JhPlsa WELLCOME BIOTECH
Cell,Vol. 57, No.7, Jur~30,1989
Tenure Track Assistant or Associate Professor Positions Department of Microbiology, Biochemistry, and Molecular Biology
University of Pittsburgh School of Medicine
The Department of Microbiology, Biochemistry, and Molecular Biology, University of Pittsburgh School of Medicine, invites applications for several tenure track assistant or associate professor positions. In 1990, the department will move into 38,tlCNl square feet of a new Basic Biomedical Research Building. Over the next three years, eight to ten new faculty will be recruited. All positions will require a teaching commitment in our medical school biochemistry or microbiology courses and participation in a combined graduate program. New laboratory facilities, start-up funds, and access to a full complement of modern ccre facilities will be available. Candidates must have a Ph. D. or M. D. degree with postdoctoral experience and a demonstrated ability to develop an independent and productive research program. Individuals with research interests in molecular pathogenesis, virology, immunology, gene expression and oncogene biology, protein structure and design, and developmental biology to include gene transfer techniques are especially encouraged to apply. Send curriculum vitae, a statement of research interests and the names of three references to:
Dr. Joseph C. Glorioso, Chairman Unlverslty of Pittsburgh School of Medlcine
Department of Microbiology, Biochemistry, and Molecular Biology 718C Scaife Hall
Pittsburgh, PA 15281.
Postdoctoral Position Molecular Oncology Columbia University Two postdoctoral fel low/research associate positions are available in a new laboratory in the Division of Cellular and Molecular Biology of the Department of Pathology to study the molecular mechanisms involved in the growth and differentiation of normal and neoplastic human B-cells. The following lines of research are being pursued: i) elucidation of the mechanism of regulation of the c-myc protooncogene. In particular, a negative auto-regulatory mechanism of the c-myc gene has been identified and characterized allowing for further studies on the identification of proteins and genes mediating this mechanism and its derangement on growth-transformed cells; ii) structural and functional characterization of novel oncogenes identified by a newly established human B-cell transformation assay. Applicants should have a-strong background in molecular genetics. Send curriculum vitae and the names and addresses of three references to: Dr. Rlccardo Dalla-Favera, Department of Pathology, Columbia University, 830 West 188th Street, New York, NY 10032.
Molecular Immunologist/Cell Biologist Department of Microbiology & Immunology University of Maryland School of Medicine
Tenure track position is available immediately for a Ph. D. or M. D. with training and research interest in molecular biology of the immune system. Preference will be given to investigators in the fields of regulation of gene expression and molecular genetics of lymphocyte receptors. The appointee is expected to establish an independent research program within an expanding academic department with research activities in molecular and cellular immunology, immunopathology of viral infections including HIV, and pathogenesis of rickettslal and parasitic diseases. Send curriculum vitae, description of research interest, list of publications and names and addresses of references to: Jan Cerny, M. D., Ph. D. Department of Microbiology & Immunology University of Maryland School of Medicine 880 West Redwood Street Howard Hall/Room 345 Baltimore, MD 21201.
Cell, Vol. 57, No. 7, June 30, 1969
POSTDOCTORAL FELLOWSHIPS IN MOLECULAR STUDIES OF EVOLUTION
Alfred P . Sloan Foundation
Up to ten postdoctoral awards in molecu- lar studies of evolution are available. Total compensation for each award is $25,000 plus $10,000 research funds per year. The awards are tenable for 1 to 2 years at uni- versities or non-profit research institutions in the United States or Canada. Applicants should be prospective or recent Ph.D.‘s in molecular biology, evolutionary biology, or related discipline. The deadline for receipt of all application materials is September 8, 1989. For details contact:
Dr. Michael S. Teitelbaum Alfred P. Sloan Foundation
630 Fifth Avenue, Suite 2550 New York, NY 10111
Molecular Cell Biologist School of Medicine Emory University The Department of Anatomy and Cell Biology at Emory University invites applications for a tenure track position at the Assistant/Associate Professor level. Candidates must have a Ph. D. or M D. degree, competitive research program and publication record, and be able to participate in team taught courses in cell biology. Individuals with demonstrated excellence in research with molecular approaches are especially encouraged to apply. Specific research programs migh include mechanisms of eukaryotic gene regulation, cell surface-cytoskeleton interaction, role of oncogenes, expression and regulation of receptors or ion channels, and molecular aspects of the action of hormones or growth factors. Interviews will begin in early Fall. Candidates should submit a letter of application, curriculum vitae, key reprints, brief description of research interests, and names and addresses of three references to: Dr. W. S. Sale, Search Committee, Roon 100, c/o Ms. M. Patterson-Roberts, Department of Anatomy and Cell Biology, Emory University School < Medicine, Atlanta, GA 30332. Emory University is an Equal Opportunity/Affirmati~ Action Employer.
RESEARCH ASSOCIATE PHARMACOLOGY
Research Associate, Pharmacology- To conduct the uptake studies of anti-aids agents In monocytio lymphoid cell lines, and to determine from tissue culture the antiviral activity of these drugs in human immunodeficiency virus infected cell lines. THe candidate will also conduct studies of pharmacokinetics and enzymatic experiments in mice and rabbits to determine the extent and rate of various prodrugs of AZT (azidothymidine) in brain tissue and cerebrospinal fluid. Candidate should be familiar with modern techniques such as: tissue culture, cytotoxicity measurements, metabolic studies, animal care and handling, enzymatic studies and computer graphic. The candidate along with familiarization of techniques such as cytotoxity measurements and metabolic studies must be familiar with computer graphics and HPLC (High Pressure Liquid Chromatography). A Ph. D. in Pharmacology or Microbiology is required. Must have a minimum six months experience as Research Assistant. 40 hours per week, 8:W a. m. to 5:OO p. m.. Salary $10.13 per hour. Contact:
Louisiana Office of Employment Security 617 Saint Charles Avenue New Orleans, IA 70130.
Job Order Number 550593 Equal Oppottunity Employer.
Cell, Vol. 57, No. 7, June 30, 1989
Postdoctoral Position Department of Cellular and Structural Biology University of Colorado School of Medicine
A position is available to study the control of nuclear structure and function through the cell cycle. Current research is examining the regulation of nuclear envelope assembly-disassembly and chromosome condensationdecondensation in cell-free extracts of Xenopus laevis eggs.
Interested applicants should send curriculum vitae, description of research background and the names and addresses of three references to:
Dr. Manfred Lohka Department of Cellular and Structural Biology University of Colorado Health Sciences Center 4200 East 9th Avenue, B-l 11 Denver, CO 80202.
Institute of Medical and Veterinary Science Adelaide, Australia
POST DOCTORAL POSITIONS
in the Division of Human Immunology in the areas of
l Growth factor design and expression l Transcriptional regulation of growth
factor genes l Vascular Cell Biology Experience in either protein chemistry, molecular biology or cell biology are required. The Division is engaged in research on growth factors and has active Cell Biology, Molecular Biology and Biochemistry sections as well as clinical interests. Positions will be available from September, 1989, for 2 years in the first instance. Salaries and conditions will be in accordance with NH & MRC Regulations. Further information may be obtained from the Head of the Division: PmfessorM.A.Vadas,I.M.V.S. Box 14, Rundle Mall Post Office Adelaide, 5000, Australia. Closing date for applications is July 31st, 1989. $
Postdoctoral Fellow Cloning and Expression of interferon Receptors University of Medicine and Dentistry of New Jersey Position available, starting immediately or as late as December 1, 1989 for two years. Studies of interferon receptors, particularly by cloning and expression of native or genetically engineered receptors in eukaryotic systems. Other receptors may be similarly studied as comparative or complementary systems. Ph. D. with experience in recombinant DNA technology and eukaryotic expression systems strongly preferred. The Medical School (formerly Rutgers Medical School) is a rapidly growing institution adjacent to the Science campus of Rutgers and the New Jersey Center for Advanced Biotechnology and Medicine (CABM). The department is particularly strong in interferon research, virology and recombinant DNA technology. We are located in central New Jersey, about one hour from Manhattan and one and a half hours from Philadelphia. Send curriculum vitae and names of three references to: Dr. Jerome A Langer, Department of Molecular Genetics 61 Mlcroblology, UMDNJ-Rober Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854-5635. Phone: (201) 463-5224.