Post-transcriptional processes

Bibliography of the current world literature

This bibliography is compiled from the journals listed at the end of the issue. It consists of literature scanned between 1 June 1988 and 31 May 1989. The bibliography has been conveniently grouped into topics which relate

to the reviews in this issue.

• Papers considered by the reviewers to be of interest. • • Papers considered by the reviewers to be of outstanding interest.

The number in square brackets following a selected paper, e.g. [7], refers to its number in the annotated references of the corresponding review.

Post-transcriptional processes

Messenger RNA modification

A ~ R ~ t JM, F ~ 3 ~ JE, STt~r i~ Character~atioo of • cytochrome C oxidase HI ~ p t s that ace

edited only In the 3' region. Ce/ /1~ , 55:267-272. [24].

• ~ ' ~ EJ. SA3ff2qA SK, ULSRICH N: ~-sarcin cause• a specific cut In 28 S rRNA when ruler•injected Into Xenotm~ tmcytes, l Biol C ~ n 1988, 263:17076-17083.

ALTSTE~q M, GA~ff.g tL- Dtffece~tial biosynthesis and posttnmsiat innal proceming o f ~ i n and oxymcin In rat brain during embryonic and postt~tal development, f ?;eurosci 1988, 8:3967-3977.

AMRELN111, GERMAN M, NOT~GER ~ T][~ sex-determining gene t r y 2 o f Drosophila extcodes a putative RNA

protein. Ce//1988, 55:1025-1035. BxSS Bt, WF~a~Atm !I: An unwindln 8 acthrliy that • o covalently modifies Its double-stranded RNA

m~b~trate. Cd/1988, 35:1(389--1098. [9]. BASS BL, WE~rn~UB tL CATr&~O IL Bn2z'r~ b ~ Biased • • hy- t ,g~eta t ion o f viral RNA genomes could

be due to unwinding/modif icet ion of double- 8ta'andtd RNA Better]. Ce//1989, 56:331. [16].

BELL l ~ ~ EM, SCHEDL P, CI~z TW: Se~/egha~ a Drmophl la sex de•errata,•fen sw/tch gtme, • .~hlhtts sex-sl~-dfi e RNA ~pl ldng ~ sequelace s tmlb~ty to RNx binding l n ~ e t m . CeU ~9~, 55:1037-1046.

BF2Z~'E R: RNA-editin 8 In ~ c ~ o m e mitochondr t~ o • Bi36/~'m B~f/7),.46ta 1969, 1007:131-139. [20]. BEUaX~ E, Gm~gr T, H~'~ J, KO2Z~L JA, BEtm~ B: • Evolution of the igenome and the genetic

code: selection at the d lnudeot ide level by methylminn and polyrlbonuclemtde cleavage. Prt~ Naa Ac, ad S o . / ~ 1~9~ 86:192-196. [3].

BOSTROM K, LALV.R S J, POKSAY KS, ~ I A Z, TAYIDR JM, • t ~ Tl~ Aimllpoprotein B48 ICNA edit ing

in chimeric apol lpopmt¢in CB. J B~dG~-m 1~9, 264:15701-15~ [4].

CArr~,a~o R. KAEtm K, BACZ~O K, BnJ~r~. M& Measles 0o virus edRin 8 provides an addltiomd cysteine-

r ich protein. Ce//1989, 54~.759-764. [t9]. CA'rrA..',~O R, SCILM~ A, SPIELIIOFER P, KAEI~q K, BA~O K, • TEa M~ULF.N V, pAB~OWnZ J, FL~',~AGA.'~ S, P~',t~ BK, UDLM

SA, BIUE1V.R MA: Mutated and hy-t,g~outated 8~nes of peesistent measles viruses which caused lethal human bcain ~ . t"irv/qg,, in press: lt~l.

O t ~ S-H, WU JH, LI X, LtAO WSI, CK,.,¢ I~ RNA edt t lag In mammal~ is not confined to apollpoproteht B. J Ceil B/a 1989, I09.96a.

OAgg JM~ Nov,el non-templsted nucleotide m, dtditlon reactinm catalyzed by ~ o t i c and e~a~aryotle DNA polymg~'a~. Nuc/e~ Adds Res 1988, 16:9677-9736.

CO~xILO PS, GRAY MW: RNA edit ing In plant • mitocho~drla. Nature 1989, 341~62-666. [28]. DA;'II~ON NO, ~ LM, WAIL/S SC, SCOTT j: Thyroid • hormooe modulates the introductinn of a stop

codon In rat l iver apollpoprotein B messenger RNA. f B:~3/Ox, m 1988, 263:13482-13485. [71.

Dxx~.s MS, WMJaS SC, Dg~COLL DM, W'/~",X JK, WRJa&~ts GW, • PO~XLL LM, ScoYr J: Sequence requlrtmaents for

apollpoprotein B RNA edit ing in transfected rat helm•Ore• cells, jr B/c/Ox.m 1989. 264:13395-13398. [11.

D i ~ JN, WAHBA AJ: Mechanism of the nu¢.leotide each•riSe reaction In eukaryotic pulypeptide chain init iation. Characterizstino of the guanine nucleotide exchange factor am a GTP-binding protein. J B/o/O~em 1989, 264346-550.

Dm~LL DM, WY~.~'E JK, WALL!S SC, SCOTt J: An/71 tat•to • o system for the edl t in 8 o f apolipoprotein B

mRNA. Ce~ 1989, J8:519-525. [2]. FEAGL'q JE. ABRAHAM JM, STUArt K: Extenslv~ editing 00 of the cytochrome C 0 x i d a ~ m transcript in

T ~ brucel. Ce//1988, 53:413-422. [25]. FORD MJ, A.~,qON IA, LA.%~ DP: Nuclear protein with • sequence homology to trattsiatlon fohlat lon

factor elF-4A [letter]. Nature 1988, 332:736-737. it31.

GUMBEgro J~ L LLMAvrt2qA L, BOh.'NARD G, WEILJ tL • GRm,%X,'~ERGER J-M: RNA edit ing in wheat

mltochondrla results in the conserradon o f pro•t-in sequences. Nature 1989, ~411~3(=~O~362. [27].

I~.SEL I~ ~3X';INGER B, SOR3STER W, BRL%~CI~ A: RNA • edhlng In plant mitochondrla. Science, In press:

1291. IImLL'~ 11, .Y~rmFF~q~R M, RLgT~ T, STAHL 1[: RNA hellca~e • activity a.~odated with the human l~g peotein

[letter]. Nature 1989, 339:%2-564. [14]. JACKS T, blx~t~a liD, MASV~Z FR, VAS.ML'S HE: Signals for

ribosomal frameshifting In the rous sarcoma 8a~po/ reg ion . Cd/1988, 55:447-458.

KIK3Om~ S, LAWRENCE J-J: Processing of p53 mRNA dur ing Induced differentiation of routine erythroleukemia cells: Is an altered splicing mechanism tx-ponsible for the post- transcrlptinnal control o f gene expression? Gene 1988, 72:177.

KIMELK~.'q D, KIRSVL%XR blW: An a n ~ mRNA directs • e the covalent modification of the transcript

encoding fibrobiast growth factor In Xenopus oucytes. CeU 1989, ~9.687-696. [t2I.

btAIZE~ N, WEL'~R & RNA editing: In s,~J'ch of a O• template. Nature 1988, 334:469-470. [26]. Mb'~t~'I~ T, NISt~<AWA K, NEMOTO F, K t ~ O Y, • NtmlL'-~A S, ~A.ZAWA T, yOKOYA.%~, S: Codon and

amino-acid spectficltles of a transfer RNA are both converted by a s insle p O s t - ~ p t l o n a l modification [letter]. Nature 1988, 3.36:179-181. [6"].

ML'RA.~ff~U T, YOKOYAMA S, HO~ N, MATSUUA A, UEDA T, • Y£~tMZLq~I 7., KUCHL'NO Y, NISrfL'~LV, A S, MIYAZAv~A T: A

nov t l lysine-substltuted nude • s ide in the first posi t ion of the an t ic •don of minor isuleucine tRNA from ~ co~ J B/o/¢~om 1988, 263:9261-9267. [5]-

lq/¢~,yA.~l p, R ~ ' q F/~E An D~ tqtro •3,stem for • accurate methylat inn of Internal adenoeine

re~ldoes In ~ RNA. Scwnce 1988. 242:1159-1161. [8].

NOILM&NZy J, ABELSON J: tRNA Identity. Annu Rev Bioc.h'.m • 1989, 58:1029-1049. [30]. PAPas J, Os13o~\~ 1 I]3, COUTLV.mR A, I£ GUELt£C R, PIIILLIPPE

~ t-hart~-S In the polyadenyiation of specific stable RNA dur ing the early development o f X ~ / a e t ~ t s . Gene 1988, 72:169-176.

Rg~3EL L~L I~'OL',7~Z-To.%~S C, D.~ftrs ME, G.~GUO P: Poll•virus-induced modification of host cell RNA polymerase 110 is prevented by cycfohexhnide and zinc. J B:k~/C~.m 1988, 263:19267-19269.

SO/EFF~Y.R M, KN'IPPEI~ R, STAHL li: ILNA unwinding • acttvity of SV40 iarSe T antigen. Ce//1989,

57:955-963. [15]. SeaPsoN L SHAW J: ILNA editing and the mltochondrial I t crypt•genes of kinetoplastid protozoa. Ce//1989.

57355-566. [21]. STUART K: T ~ o • o n l a t i d s : taltochondrtal RNA 00 e d i t i n g - - a minh'evtew. E.~Paraslro/1989,

68:~-490. [22]. STuARt K, FEAGL~ JE, AB~t~M J.~ RNA •dittoS: the • e re • t i e • of n u d e • t i d e sequences In mlU~IA - -

a mlnletwiew. Gene 1989, 82:155-160. [23]. TEIL'~ MP, JACOB ST: Role of puly(A) pulymeras, e In

the cleavage and pulyadenyiation of mRNA precursor. 3Io/Ceil El•~ 1989, 9:1 ~L55-1444.

THOM~ SM, L ~ RA, p^TEW, ON RG: Two mRNAs that • • differ by two nontemplated nudeolldes encode

the amino coterminal proteins P and V of the paramyxoviru$ SVS. Ce//1988, 54.891--902. [18].

WAGNER 1~7, NISI~(URA I~ A l l a~21tl~tfy In • cells which modifies adenosines to In•sines In

double-stranded RNA, J Cefl Biol I989,109~96a. [11]. WAGN'~R R~', SMITH JE, COOPEILMAN B~, N ~ S | ~ A ]Q • A double-stranded RNA unwinding activity

Introduces structural alterations by me*ns of adenosine to In•s ine conveeslons In mammalian cells and XenOltmS eggs. Pr0c ?;a.q Acad Sol USA 1989, 86:2647-2651. [10].

WIEBAL~ K, Jill•,3" j: In t~ ro correction of G-T • mispalrs to G-G pair* In nuclear extracts from

human cells [letter]. Nature 1989, 339:234-236. [311.

WIL~ON T, "I '~.%~ R= Foe C-terminal mutations block down-regulatfoo of c-los transcelptinn following serum stimulation. F-5/BOJ 1988, 7:4193-4202.

Gene regulation through mRNA stability

AEKE~.~V~'~ EJ. SAXXNA SK, ULB~QI N: a-sarcin camu~ a Specific cut In 28 S rRNA when mlcroinjected into Xenopus oocytes. J B ~ / ~ 1~8, 263:17076-17083.

. ~ x JF, IDDEH IW: Specific mI~NA destsbilizaflon In D k a ~ z e / ~ m dXscodt, t ~ r equ t r~ RNA synthesis. MolC.ellBiol 1988. 7:4585-A588.

A/~IGO S, BEEMON K: Regulation of toes sarcoma virus I~'A splicing and stability. Md Cell Bid l f ~ , 8A858--4867.

B.~<xEa O, A~.','BL~3 AC, NOTEBOK,~ ~fl~L WL'.qXR AJ, GAB: Turnover products of the ape very low density

(~ Current Science Lid ISSN 0955-0674 1249

1250 Post-transcriptional processes Gene regulation through mRNA stability

l ip•pro te in H me.~.nger RNA from chicken liver. A'uc2e~ Ac/ds Res 1988, 16:10109-I0130.

BAI£m,~ F JR, O~'~X "l~l, Fff~ATR~CK-bICELUGOTr S, WOL~ON B: Coordinate hormonal and synoptic regulation or W r e s s i n m ~ s e r RNA. M/once 1988, 241:978-980.

BARBtEPa L, BOtOGN~St A, CF~,,'e,a P, FAtASC~ AI, I~NGHETTI A, GAROF&NO L, GUICCIARDI A, LAPPI D, ~,~LIY-R SP, STW.PE F: Rlbosome-inactlvating proteins from plant ceils in culture. Bi(~lwm.]1989, 257:801-807.

BEt&~CO JG, CH~,~ C-YA: Mechanism of puf mRNA degradation: the role of an intercistronlc stem- loop structure. Gene 1988, 72:109-117.

BELASCO JG, tfIGGIN~ CF: Mechanisms of mRNA decay In • bacteria: a perspective. Gone 1988, 72:15-23. [1]. BE~.NSTELN P, PEL~Z SW, RC6S J: The poly(A)-poly(A)- • b inding protein complex is a major determinant

o f m~NA stsbll i ty in vOrtx 3f~/Ce~-/Bio11989, 9:659-670. [71.

BETT&NT ArE, tOUGHI~ L, MOORE J: Messenger RNA degradation in S a c v b a ~ cerm,/s/a~ Gone 1988, 72:151-160.

BREWER G, Rc6s J: Regulation o f c-myc mRNA stabili ty • • bt t ,4 tmbyalab l ledes ta lMl izerwt thanessen t la l

nucleic a d d compot~oL MO/Ce//Eta/1989, 9:1996-2006. [S].

BuOct~ AJ, Vm IL SONX'~tE~ GE,/~LLER R& Defective T IFmphocytes In old mice: d iminished production of mature c-myc ml tosen exposure not attributable to alteratinns in ~ p t i o n or RNA stability. J lmmuno11988, 140:2442-2446.

CARTER KC, COOPER R, PAPACON.'STA.~ J, RrroIIE DG= Mit t • tubule depolymerlaaflon Inhibits the regulation of al-ucld glycoprotein mRNA by hepatocyte st imulating factor. J Biol O>em 1989, 264;515-519.

CASEY JL, HENqX~ blW, KOELLER DM, CAUGtLMAN SW, ROUAULT 0 • TA, KIAL.~'*'ER RD, ILM~=ORDJB: Iron-rgsponsiv~

elements: regulatory RNA sequences that cootrol mRNA levels and translation..~k, nce 1988, 240;924-928. [14].

OtXN U:/mtl-lgM antibodies inhibi t lgM expression In lipopohlsa¢charld¢-stimulated normal murtne B-cells study of RNA metabolism and translation. Gone 1508, 72:209-217.

OtOUD~tL~ K, CHOUt~tL~Y 1, Euc~tm GI~ Metabolism of small RNAs in cultured human celis.JCellpI~,tol 1989,138:433.

CI~XL~ND DW: Autoregulated lxuttahillty of tubul in mRNA~: a novel eukaryotlc regulatory mechanism. Trends Biocbem Set 1988,13339-342.

C.OOtg~N'E AW, DEELEY RG: E s t r o g e ~ t activation of the avian very low density apolipoprotein I1 and vi tel logentn genes. Tr~mslent alterations In mRNA poIy~denylatinn and smblllty early dur ing Induction. f M~/B/o/ 1988, 203:555-568.

CU~tL',W,S A. SO,%~0,'tLLE J: Protein activ/ty associated with stored messenger r i b • n u d e • p r o t e i n imrtidea o f Xenopu* oocytes. J Co//Bt~/19~, 107:45-56.

DAAR 10, MAQUAT IF: Preolat~re ~ l a t l o n • termlo.tt lon mediates triopho*phat¢ i somera~

mRNA degradation. Mo/Co//B/o/1988, 8:802-813. [20].

DA',IS BB, blAGGE S, MUCL'~K~ CG, ~ P,L: Insulin- mediated p o e t - ~ r l p t i o m d regulation of hepatic mallc enzyme and albumin mRNA~. Bio6bem B i q ~ s Res Common 1~88, 154:1081-1C67.

EISLNSI~N RS, ROSEN J.M: Both cell sub~trt tum • regulation and hoemomd regulation of milk

protein gene expression are exerted primarily at the po*ttranscrlptinnal k"veL M~/Ce//B/o/1988, 8:3183-3190. [2].

EP.X~r "I'J, RtTCHIE AR, DLMETRI GD, GP.WF~ ~ gegulatloB of granuloo/t¢- and ~ ¢ - ¢ o l o n y s t imula th~ factor mILNA levels In bnman blood mooocy t~ Is mediated primarily at a p o ~ t * ~ p l l o n a l leveLJBiol~ern 1989, 264:5700-5703.

FFa~F~ BK, lime_OPOULOUCtTd~S, ~ C, COPEL~ND T, PA~ZAKIS GN: l lev protein of human immonodef idency v i rus type I affects the st.xblllty mad transport o f the viral tuRN&. Proc Nat/Acad ~ 1989, 86:1495-1499.

FLORES S, TOBLN F.~ Cytokln|n modulat ion of LIlCP mRNA levels: the involvement o f po*t- ~ p l l o n a l rggulallon, PlantMolEiolI988, 11.-409-416.

FOMLNAYA JM, G.,.XCaA.SEGU'RA .D,i, GA~.~.A.W.S JG= RIbO~-RNA.~ inhib i tor complex from rat testis. Porification o f the RNAase inhibitor . Bioc~m B~r~s Acta 1988, 954:216-223.

GAY DA, SISODL:~ SS, CLE~ZIAND I~gg': Autort'gulatory • control o f beta tubulin m]LNA stability is l inked

to translation elongation. Pr0C ?,~d Acad 5a USA 1989, 86:5763-5767. [5].

GIBSON WC. ~ BW, BURST P: Po0t-transcrtptlothal control o f the dtfferemlal expression of phnsphoglycerate kin•so genes In Trypanosoma M J Ma Bib/1988, 201".315-326.

GONG Z, BX~.'~T~ORST B: Autogenous regulation of tubul in ~ t h e s l $ v/a RNA stability dur ing sea u txhln embryoBenesis. De~/qOment 1988, 10231-43.

GONG Z, BRANDItORST B: Autogenous regulation of tubulin sTnthesL~ t4a I~NA stabllity during sea urchin embcyoBenesis. De~/~pment 198~. 10231-44.

GONG Z, BPA.N'DItORST BP: $tabifiz~tlon of tubul ln mRNA by Inhibit ion of protein synthesis In sea urchin embcyns. Mo/Co//Bio11988, 83518-3525.

GROSS G, ttOLLATZ I- Coliphatge lambda t o terminator lowers the stability o f mes.*etxger l~WA In Eacberk~a co//h~sts. Gone 1988, 72:119-128.

HARLA.~'O R, MISHXR L: 5tabLilty o f RNA in do t • lop ing X e n o / ~ embtTos and identification o f a de$tablli~|rt s s~ue~ce in ~ m e ~ - ~ g f f l~kNA. Det~/~ment 1988,102.837-852.

}t£RRLrER ?~t, MAGER ~ i , R.~.L~ ]IA, VREKY.N P, WtLMS E, PLANTA RJ: Mild temperature shock affects ~ p t i o n of yeast ribosomal protein geues as well as the stability of thei r ml~NAs. A'tw./e/~ Ack/s Res 1988,16:7917.

HIGGLX5 CF, M ~ ' q I~ NE~'i3L'RY SF: REP sequences, mRNA stablJlty and gone exprtSslon: evolution by gone conversIoo? - - a re•dew. Gone 1988, 723-14.

ttOKIGUOU J, S.,¢~l/~.'q E, KLTI~ D:. T ~ p t i o n a l and posttransertpttonal regulation of ~ 1 gene e x p r t ~ i o n In human monocytes. Mo/Ce/ /B~ / 1988, 83951-3954.

IIUR,~m M. PALKAMA T, SI~XXA ~ In ter leukin4 |nhlhlt~ interIeuidn-1 synthesis by a post-transcriptional mt'~hanl~m. BR~l~em B i o ~ l~s Commun 1988, 157:861~866.

IT• M, BELL J, LYO:,~ G, I',L,XXSON R: Synthesis turnover of late H2B his tone nx]~NlA In developing embrytm of the sea urchin, $tronay/ocentron~ purpu ratu~ Dev B ~ ~988, 129:147-158.

JL',?~O Y, M£RLL'O GT, PAST&'~ 1: A novel effect of EGF on mRNA stability." Nude~ ~ Res 1988,16:4957-4988.

KAB.X'ICK KS, IIOUSMA.'q DE: Determinants that • contribute to cy topi~mlc stability o f hnman

c-ft~ and [~llobin mRNA~ are located at ~ v e r a l sites in each mRNA. MolCelIBiol1988, 8:3244-3250. I l l ] .

KATSUKM3A A, IRITA.Nq N, FLq~'DA H, NOGUO41 T, TAN.MOt T: Transcriptional and p o ~ p t i O t x a i relpalation of malic enzyme synthesis by h ~ u l l n and trtindothyronlne. Biochim B i o t ~ A~ta 1988, 950:113-117.

KEOLLER DM, CASEY JL, lIL~qTz MW, G E ~ E~L CH&N 00 LN, KLAUS.N'ER P~, HARFORD JB: A C~gO~'OliC protein

binds to structural elements wi thin the iron regulatory region of the transferrin receptor mRNA. Pro~ Nad Acad So/USA 1989, 863574-3578. [181.

KIL-,x~'q SP, HOL~mS K~ MORSE IIC m, THOP.GEmSSON 5,5: T ~ p t i o n a l and poet-transcripllonal relF~lation of omyG c.myb~ and p53 during proliferation and differentiation o f routine crythroleukemla ceils treated with DFMO and DMSO. ~ Ce//Res 1988,178:185-198.

KOZXK M: Leader length and secondary s t r u m modulate mgNA function under cot~ditinns o f stress. Mo/Ce//Bt2~/1988, 8:2737-2744.

LEE ~ F , L~ C, CURP~.N T; Activation of the trtamfot'mhtg potential o f the human fo* pluto- oncogene r~lUires message stabilization and results In Increased amounts of partially modified foe protein. Mot Ce//E/o/1988, 8:5521-5527.

IIF.BOU3 EA, MU?~O ILN: C~opla~mlc protein bin¢is • tin tsttr~ to a hl#aly comu.-rved aequence in the

5 untrmmlated region of ferrl t ln heavy- and l l ~ t a u b m f l t mLN&s. Pr0c Natl Acad Sol ~ 1988, 85:2172-2175. [161-

LDa3S3~N T, JUNX CAL THO.Va~ON CB: Mnlttple m ~ m s regulate o m y c gene expre~ ion dur ing normad T cell activation. ~ f B O f 19~, 7:2787-2794.

LOUIS JM, MCFAm~\'D VW, ~9.Y P, MOK', IT: The pho~phoprotein p53 is down-regulated po0t-

U'anscriptlonally dur ing emb~-ogenesls In vertebrates. B:~bira B ~ A c t a 1988, 950395-402.

LO~ HI), ALLEN-K~H A JR, Z~L~,O Q, K~.',.~ON GA: mRNA stability p l~ ' s a major role in regulating the temperature-specific expression of a Tetrabymena thermopbaa surface protein. 3Io/ Ce//B/o/1988, 8:427-432.

M~',mOw RE, JXCOBSON k mltNA decay rate* In late- developing DkW)~ukVdum disroideum cells are heterogeneous, and cyclic AMP does not act directly to stabilize cell-type-specific ml~NAs. MOl Cell BR~/1988, 8:4088-4097.

I~L~N'~OW RE, SHAPIRO IL~, HERmCK D, STEEL LF, BILN'DER D, J.~COBSON A: Regulation of mRNA stabifity and the poly(A) problem in DtcO'ostelium ~ m ~ Dev Goner 1988, 9:403--420.

M,&'CONI RT, IIILL WE: Evidence for a tRNA./riLNA interaction site wi thin the peptidyltransferase center o f the ~ coli ribosome. B/x_bem/str_v 1989, 28:893-899.

MARZIL'FF WF. PA.','OEY h'B: Multiple regulatory steps • control hL~tooe mlLNA concentrations. Trends

B~2x:bem Sc/1988,13:49-52. [3[. M~5ON JO, WILt.~5 GT, NEL~BF.RGR ~,LS; The half-life of

tmmuooglobulin miLNA lncreas~ during B-cell dtfferentlatloo: a possible role for targeting to membrane-bound poIysomes. Genes Dev I988. 2:1003-1011.

MCCLL~ B.~ GLqLFO~E T: Rapid redistr ibut ion of auxin-regulated RNAs dur ing gravttrCqDlsm. SoL•nee 1989, 243:91-92.

l~ss~qA Jh Insulin and deamJm.ethasone regulation of a rat helmtoma me~enger ribonuclelc acid: insul in ha* a transcriptional and a postteanscrtptional effect. End•or/no/•D, 1989, 124:754-761.

MC~L,%'ER EW, KCVLN LC: A stem-loop In the 3 * untranslated region mediates lron-dependtmt

tx-gulatlon of transferrtn receptor mRNA stability in the cytoplasm. Co//1988, 53:815-825. 115].

MUH.N'ER E~', IqELTERT B, KL1LN LC: A SpeCifiC mRNA • binding factor regulates the iron-dependent

stabRlty of cytoplasmlc transferrin receptor mi~NA. Ce//1989, 58:373-382. [17].

MLq~LIDItAR MG, JOItNSON IF: Delayed proceed- Ing/export or messenger l~NA under condit ions of rt, duced protein ~ynthesta. J Co//P/~/1988, 135:115-121.

PACE CN. G~xtst£Y GP~ Rlbonuclease T I is stabilized by cation attd anlon bhadirtg. B.*~tn/stry 1588, 27:3242-32~15.

PARIS J, OSBORNE liB, COUTLq~IER A, LE GCELLEC R, I>Fm.LIPPE l~t Oh.noes in the polyadenylation of specific stable 1LNA during the early development of Xenopua ~ Gene 1988, 72:169-176.

PAYIWI~N BV, RL,~EL R, BACHVAROVA P,: ~han~.eS in state of adenylatinn and t ime course of degradation of maternal mRNAs dur ing oocyte maturation and early embryonic development in the mouse. Dev Bio11988,129:304-314.

PEI R, CAL~m K: Differential stability o f o m y c • mRNA.~ in a cell-free tWstem. Mo/CeU B/o/1988 ,

8 : 2 8 6 0 - ~ . [9]. Pr2¢I'r~x'~ RP, KOBAY~HI S, BOR.',~I'EL~ P: Tran*forming

growth factor ~ Increases mI~NA for matrix proteins both in the presence and in the absence of changes in ml~NA stability, proc Nat/ Ac-ad S~f UX4 1988, 85:1105-1108.

P~xI~,oN R, I~'DQLaST S: The ~ hsp70 message is rzpldly degraded at normal temperature and stablized by heat shock. Gone 1988, 72:161-168.

PRA.V~',~K SK, MEADCS WJ, BAG J: Regulation or translation and stability of an mRNA coding for a 40-kD-a polypeptide In rat L6 muscle cells. Eur f Bt~bem 1988, 172:355-362.

PRENDERGAST GC, COLE MD: l ~ 0 ~ r i p t i o n a l regulation of cellular gene expresglon by the omye oncogene. Mo/Ce//B/0/198% 9:124-134.

PRESS gD, S&~tOLS D, GOLDTH~AI"r DA: Expression and stahillty of c-sis m~NA in human glioblastoma cells. B/00~m/m 7 1988, 27:5736-5741.

RAO TR, SLOB~ H: The stability of mRNA for eucaryotic elongation factor Tu In friend erytht~leukemla cells v-aries with ~ o w t h rate. MO/ Co// Eke/1988, 8:1085-1092.

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ZAMOFING D, RO6SmR BC, GF2mLNG K: iinle of the Na, K- ATl~ase [~-snbtmlt In the cellular accumulat ion and matura t ion of the em3m~e as by glyco~l~Uon Inhibltors. JMembr Bio11988, 104~)-79.

Protein carboxyl methylation

.AD~M AA, ~,~.~'t'rX DE, Co~e~ Z& interferon y Induces the myvistoylation of a 48-kDa pro te in In macropkag~. Pr~ Natl Acad Sct USA 1988, 75.6310-6313.

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/[.RATA.N[ Y, KITAGAWA Y: T y r ~ i n e sulflttlon Is not the last modif icat ion of enta~ttn before i ts secggtlon f rom 3T3-LI adipocytes. F E ~ Le/t 1988, 235:129-152.

AriEL C, MAgY D, PEY~3N J-F, PELAS~ C, FERRt~ B, FEHL~,¢A.~ ~.~ Inhibi t ion ~ ~ctiv'~tlon of inter tsukin 2 wlnthe*is by direct modificat ion of g t tmo*tne tr iphoephate-hindin 8 p ro te im. J Immuno119~8. 140:215-220.

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RJ, C.AIA~JC, DUFAU M]2 P r o i . ~ t n differgntL~lly a~ects bacterial toxin-induced ADp-ribosylation of Nb 2 l y m p h • m s cell membrane p r o t e i n . B~c.,bem B/0f~s Res C0rnmun 1988,156:776-782.

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BOKOOt GM, PAr, K•6 CA, ML~tBY S~ Purification and chacactertzation of the 22,000-dalton GTP- b inding pro te in substrate for ADP.ribosylation by botu t inum toxin , G22~. J B~/¢2~n 1988, 263:16744-16749.

BOLEO~R JG~L xx'~ DER BIJL/~L~fW, NEEF~ JJ, IIXLt A, SMETS I.A, PLOEGIt 1ti..Rag (pro to)oncogrne Induces N-l~nked carbohydrate modification: temporal re la t ionship wi th Induction of Inv-asive potential . J ~ O J 1988, 7:3361-3368.

BOO~ JA, Ztsr, x SE, I IL\'EmRSO:q EJ: Defective Inteccelinlag cohes ion in 81ycosylation mutan ts o f Dtayosteilum ~ Dev Genet 1988, 9:569-578.

BOSO~ M, T~OStBmA S, ~ i U, PAROD~ AJ: Char- actecLtation o f dollchol dipho*phate ollgosacchartde: prote in oilgosaccharyltransfet-ase and glycoprotein-processing gluco~ldases occurr ing In trYlpamos, omatld protozoa. J B/o/(/~rn 1988, 263:17.~0-17365.

BR~X~DU AW, tI~.NSSON ~ , I~DDRIGUF.Z-BOUI~N E, SLMON~ K: A polarized e p l t h e M cell mutant d e ' d e n t in ~ l o c ~ f l o n o f UDP-salactose Into the Golgi complex. JBiol t2g.m 1988, 263:16283-16290.

B R ~ KC, REG&N C ~ Developmental control o f N- CAM slalylation state by Golgt slalylLransfera~ Is•forms. D c t ~ e n t 1988,104:147-154.

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BROWhX.~/~L CERAX~ /~ ~ 1E Advanced glycos3'latinn end products In t l~ue and the b tochemtad i~a~is of d ia ly t ic complications. N EnglJ Med lg~8, 318:1315-1321.

BULL~I~ JC, RIOLM{DS JE, PIpER.'~O G: P o o ~ i a t | o l ~ t l modification of ~t tubulln: d¢wro~ination and acetylatlon differentiate popuist lons of lnterphase mlcrotubule$ In cultured cells. J Ce~ B/d 1988, 156:1213--1220.

BL~E~S AJ, NOPO.tAN RI= The large glycoprotein subuni t o f the skeletal muscle voltage-sensitive calcium channel ~ deglycnsylat ion and development . EurJBiocbem 1988, 178:527-533.

Bb.~,s JE, DER CJ, Sots~ p& The s ix amino-terminal amino acids o f p60 *~ are suf l ic~nt to cause myrbty la t lon o f p21 v-t~. Me/Cd/Bt~ 1988, $396O-3963.

BUSS JE, SOLSKI PPh SCHAEFFER JP, M~cDoYzt.LD MJ, DER CJ: Actlvatinn o f the cellular p ro[o- • •cog•he product p21ras by addi t ion •Ca myrlstylation signal. S¢/em.e 1~9, 243:1600-1602.

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~ ' R RJ, SPin• RG: Effect o f pho~phollplds on thyroid oligosaceharl-tranMerase activity and or ientat ion. Evaluation of structural de te rmimmts for s t imulat ion of Hglycotwlaflon. JB~C~om 1988, 263:15673-15680.

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DE.SOt~,,Tr..S RJ, S'~BIEL JB, C~ARKE S, STOCK J, B~:OAOI J~ • .RA$~ prote in o f ,~ t~ba~amyo~ ¢~v~ts/~w is

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Du~ox~o V, J .~o~ s, R O ~ 3 PA, I ~ C ~ I C S & Effect~ of Inhlh~tnrs o f N-linited ollgosacchartde process ing on the biosynthesis and funct ion of Insul in and Insulin-like growth fa~of-I receptors. J B ~ G~,rn 1988, 263:5436-5445.

DisrrA A. pARmH B, MABL'q I L MEL%'YKOV~'O! G: Increased dolichol content In 8incoco~lcold-sensltive h u m a n T-cell leukemia l ine grown in the presence of dexamethasone. E~r~m B~,3~ Rc~ Commun 15~9,158:163-169.

ENG.WROM W, I.ARSSON O: The effects of glycosylation Inhihi tors on the pt~lfferatlon •Ca spontaneously t r a ~ f o r m e d cell line (3T6) tn t~r~x J c~t/Sa 1988, 9~447-456.

F~IGE JJ, BAIRD A: Glycol ' lo t ion of the b ~ l c fibroblast growth factor receptor. The contrifiution o f carbohydrate to t ' t~eptof function. J Bt2~ O~,m 19'88, 263:14023-14029.

FEIGE JJ, KELLER GA, SOtF.FF~R IE: Temperature- ~ d t i v e C h e e s e hamster cell mutant wi th a defect in glycoprotein synthesis: accumulat ion of the EGF receptor in t he endoplasmlc ret iculum and the role o f the 81ucose-regulated prote in GRP78. J C e / / F ~ & 1988, 136:33-42.

FEN1)RICK J'L, IGIEgSK1 xgJ: Endogenous ADP-ftbo6Tlation of elongat ion factor 2 In polyoma virus- t ransformed baby hamster kidney ceils. P r ~ ?,~a Ac.ad Set USA 1989, 86:554-557.

FIXES JD, BASSFORD PJJle Novel set:A alleles Improve expor t of ma i tose -b ind~g protein synthesized wi th a defective signal peptide. J Ea~er/o/19~), 171:402--409.

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FODDY ~ IIUGtlXS RC: Assembly of a s p a r a ~ e - I I n k e d ollgo-sacchartdes in baby hamster ceils t r ~ t e d wi th ¢~stano~permtt~, ma lf~hlhitor of process ing gincostdases. Eur J B ~ c m 1988, 175:291-299.

FONG I~"~', YC6HL~IOTO KK, E'XZMOL~43n~ P, SLMON ~.~ Identif icat ion of a GTP-binding prote in ~t subunlt that lacks an apparent ADp-rtbosylatlon site for per tussis toxin. P r ~ A~tlAc~ $ci ~988, 853o66-3o70.

FRmDERIOt E, FRI'IZ ttJ, tILrr'~'ER X~13: Inhibit ion o f tyrosine sulfatloo in the tran.f,-Golgl retards the t ransport o f a consti tut ively secreted prote in to the cell surface. J Cell Biol 1~8, 107:1655-1667.

GALIAGHER P, HEN%q~BERRY J, WILtL)N I, S~MBROOK J, Gzn~c , MJ: Addition o f carbohydrate slde C halo[ at novel sites on Influenza virus hemagglut in in can modulate t he folding, transport, and activity of the molecule. J Cd/B~/1988, 107:205~-2074.

GALLE'rTI p, LX'GROf, SO D, M~\.'NA C, SICA F, CAPASSO S, PUO~ • P, t , ~ (3:. Enzymatic methyl esterificatinn of

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GO.MOO S, SHX~IIZO N: Glycosyistion of the epidermal growth factor ~-ceptor and Its relat ionship of m e m b r a n e t ransport and Bg~md binding. J B~.~x.rn (To~o) 1988, 104388-396.

GEET~-HAmB ~L NOrcX R, KAPt~.N HA, LL\XM~Z ~J: Glycosylation si te b ind ing protein, a component of oHgosaccharyl teansfer-a~, is h ighly s imi lar to th ree o ther 57 kd luminal proteins of the ER. C~//1988, 54:1053-1060.

Gn nEgr JM, FO~ER A, BLEIBAUM J, Ct.~KE S: • Purification of homologous protein carboxyl

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G~-~tt~.M JM, WI2~WERBOL~XX DJ: Subcellar lo,'at~-~tion o f the sulphat ion reaction o f hepara~ sulphate ~ t h e s i s and t ransport o f the peoteoglyca~ tO the cell surface In rat liver, B ~ m J 1 9 S g , 252:437-445.

C~I3]'IER.R.~ l~ MAGEE ~J, ~J.A.~LkLL CJ, | L ~ . ~ J~: Po~t- • • translatiotxal process ing of p21-r~ is two-

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1260 Post-transcriptional processes Protein carboxyl methylation

tL~',,~OCK JF, I%~GEE AI, Oinks JE, I~SitALL CJ: All ras ee proteins are polyisoprenylated but only some

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DABROWSK~ J,DA~RO'~,~ U: Structuees o f neutral O- l inked po ly lac to~minoglyca~ on hum*~mUk muclns. A novel type o f linearly extended poly- N-acetyllacto*amine lmckbones with GadS(1. 4)GlcNa¢~(1-6) repeating units. J Biol ~ 1989, 264:872-883.

tL~I~M (3tt, CL~tI£'Y W: Simultaneous Inhibit ion of mult iple steps In the processIng o f N-inked oligosaccharides does not impair lmmunoglobin secretion fi.om rat hybridoma cells. I m m u ~ 1988, 63383-388.

HKSPEL lie, I~L~'ILLL~E J, R(~L"/OM: StrucU.Ire, biosynthesis, and function o f the hexose Umnsl~rter in Chinese hamster ovary cells deficient in N-acetyiglucosatminyltransferase 1 activity. J Ce/ /Pb)~ 1988,136361-366.

I I~LX~qGSEN S,~L WCOLFORD C, VgN DF.R VIF.~ S,~L TILLy K, Dh~,'NIS DT, G E O R ~ CP, tI£.NThRIX Rx,V, RJ: Homologous plant and bacterial proteins chaperone oligomerlc protein assembly. A'ature 1988, 333330-334.

H£NDERSHOT LM, TL';G J, lYE AS: Identity o f the immunogiobul in heavy-chain-binding proteIn with the 78,000-dahon glucose-regulated protein and the role of posttranslatlonal modifications In Its binding function. MolCellBiol1988, 8:4250-4256.

HENZEL WJ, S'rUl.'I~ j'T, 1t5o C-A, .ASWAD DW: • Primary structure of a protein carboxyl

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ttOU12 RI. S'IX~LTS Jr, MLZLIG&N R.~ TOLBEgT hE: M - t r a n s l a t i o m t l modifications In the h rge subunlt o f ribulose b isphmphate carboIyisse/oxygenas¢. Proc Nat/Acad $cl 1989, 86:1855-1859.

HL~e~O SC: Regulation o f glycosylation. The i ~ f l u e ~ e of pt'otctn S g t ~ t l f ~ Oft .NLl|nke~ oligosaccharkl¢ processing, f Biol a ~ m 1988, 263:19303--19317.

HLrMP~ DE. SILBF.RT JE: Chlorate: a rt'rga~lbl¢ Inhibi tor of proteoglyc~t su l~t lon . / U n ~ BiqOb)~i Res Commun 1988, 154:365-371.

IKEJLMA M, GILL DSt P o l y ( A D p - ~ ) ~ t i o n by glyeohydrolase starts wi th an endonudenlyt lc IndMon. JBiol C~om 1988, 263:11037-11040.

JASPEr5 B.~. DE STROOPER B, SPAEPE~N b~, VAN LEUVEN F. DA~AD G, VAN DF.N BERGHE H, ~ t A N J-J: Post-translational modification of the ~-subuntt of the human f l ~ receptor. FEB5 Left 1988, 231:402-406.

JEI.Ba~-KE1LY S, I IF.R~OVICS A: Glycoprotein biowynthesis in ~ r o m y c ~ c~-tah-/ae. Purification of the a-manno~ldase which r e m o v ~ one specific mamnose residue fa.om MangGicNAc. J ate/a~om 1988, 263:14757-14763.

J D~.N JW0 ~ JS: Modulation o f dolichyL phoeq~hom~mno~e synthase activity by chanffes in the l ipid environment o f the enzyme. B ~ m ~ r y 1988, 27.6315~320.

JG6L'~ON BA. 5~KAWA JSL &~'AD DW: INmmidattion • o f calmodulin at neutral and adkaline

pH: qmmtttative relationshllm b e ~ =mmonla loss and the susceptibili ty of calmodulin to modification by protein carboryl methyltransfex.-B¢. Arcb Bt~r../~'rn B ~ 1~9, 26&276-2~& [3].

J~e~o~ BA, Sm~Og.~WA JM, H~'~COC~ WS, SPraxx~.~ MW, oo BASA LJ, ASWAD DW: F, ormation of isoaspartate

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K~q IL% GOOOA~ C, N~WKmK M: Chemical and immunoiogtod characterization o f the 21.kDa ADP-ribosylaiton f~ctof o f ade~ylate cycla~. J B/0/awm 1988. 263.8282-8287.

KAPL~'q JM. MARDON G, BISHOP JM, VA~.~ tiE: The first seven amino acids encoded by the v-src oncogene act as a myrts tyht ion siKmd: lysine 7 is a c r l t l ad determinamt. Mo/Ce//B/0/19~, 8:2435-2441.

KM-Z F, MOATS W, JAN YN: A carbohydrate epitope expremed unlquely on the cell surface of ~ ueu~s~s Is a h e r ~ In the mutant na¢ (ueurally altered carbohydrate). F.~./BOJ 1988, 7".3471--3478.

A, Y£'4&~,gYro K. FUyffA 1", TAKAI Y: ADP- r/bosylation o f the bovine brain rbo protein

by borulinum toxin type Cl.JBiol Cbem 1988, 263:16303-163~.

KOMORI N, RIDER ~L~. TAK~MOTO DJ, S~ofl H, MATSU.~TO IL ADP-rtbosylatlon of bovine S-antigen by cholera toxin. Eioc2wm B i o p ~ Res Commun 1988, 156:11601165.

KO,~G R, ASltWELL G, tL~NO~TR JA= Glycosylatlon of CD4. Tunlcamycin Inhibits surface expression. J Biol

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modification, and Iorall*aflon of t h e . ~ tarax.u proteIn In droaopbaa embryo*. Genes Dev 1988, 2:1021-1036.

KRUPI'rZA G, CERUT~ P; ADp-rtbosylatton o f ADPR. t ransfera~ and topolsomerase 1 in Intact mous~ epidermal cells JB6. B~&-m~stry 1989, 282034-2039.

KUBO ~L STI~Tr CA= Phosphorylatinu of calmodulin on threonine residue(s) by cytosol prepared from the adrenal cortex. E~cbem B/~t~s Res Commun 1988,156:1333-1339.

LAF̂ ~XTTE PIL "I'~A~S RI~ Effect of Inhibi t ion of glyco~-lation on the appearance o f a 60-kD membrane 81ycopolypeptlde In endomembrane ft'-actions of soybean root. PIantPb3~iol1989 , 89:299-304.

L~NGER BG, Xg'EISEL J~', DLNAL~R pA, ~ g ~ f l C, BELL W~ Deglycosylatinn of fibrinoSen accelerates polymerization and Increases lateral aggregation of fibrin f ibers . fB~ol~ .m 1988, 263:1505~150d3.

I.mmxt~.~ MA, Z£,NG y: Plelotroplc resistance to glycoprotel~, proce~L~g lnhibi tors In Chinese hamster ovary ceils. The role of a novel mutat ion in the aslmragine-linked glycosylaflon pathway. J B/o/Ox'm 1989, 264:15~t-1593.

LP,'~G.WON BD, JACOI?6 JL, GHCK MC, TROY F/~ Extended poly~lalic add chains ( n ~ 55) In glycoprotehxs from human I~Uro61astom cells.JBiolOgem 1 ~ , 263:9443-9448.

MAot&x¢.~ CE, ROSE JK: Influence of new glyctmylatlon sites on exprg~lon of the vesicular stomatis virus G proteIn at the plasma m e m b r a n e . J B / ~ a m n I~8, 263:5998-5954.

MAOLL~ff-R CE, RC6E JK: Vesicular stomatit is v l r t~ G protein~ with altered glycosyh¢lon sites display temperature-setmltivt Intraceliular transport and are subject to aberrant intermolecular dlsulfute bonding. J a~/Ox-m 1 ~ , 263:5955--5960.

l~t~tl.E hT, RA~Tr.S MA, FUO~NGER TW, KUNG ttJ: Proviral Insertional activation of c-t, r6~ differential p roce~ing of the protein products arisin 8 from two altertxate transcripts. Mo/CellEd/1988, 8:4868-4876.

~L~.%~O.N'I C, DI%V.A~I M; Doxoroblcin Induces the acetylation of ldstone H1 in a human colon cancer cell l ine (LoVo/DX) selected for resistance to the drug, but not In the sensitive parental l ine (LoVo). Bloc.bern B~pb3, ~ Commun 1988,155:1221-1229.

btX~UOKA i, SAKL~t~ tL SMYro B, MoP~s~u K, KL~BO S, KUV.~d.~,A K: A D P - ~ l a t l o n of 24-26kDa GTP- b inding proteins localized in neuronal and non- neuronal cells by botul inum neurotoxtn D. J B/ol C~c'm 1989, 264:706-712.

M ~ W, TLUS'~ A, RUIT R, BLMa.t£R JN, BO~LN JA, },~ERS RW, SC~A~ RT: t~hl l~t ion of glycoprotein o ~ c h a r l d e process ing /n t~ ro and In Influenza-virns-in/ected cells by a-D- m a n n ~ l m e t h y l . p n l t r o p h e n y i t r l a z e n e . Bio¢2~mJ 1988, 255:991-998.

blF.~Lt~ MRF, LEO.XE E, bIAL&NC.,A M, F.~"O, B: ADp. rJboeylation of a specific protein from Isolated Intact bul l testis nucleL Bioc.~'m BiOf~sActa 1988, 954:58-64.

Mm~G&~ G, McKL'~m FI~ Opinid peptodes promote choleca-toxin-catalysed ADP-ribo~ylation of the inhibi tory gmmtne-nucleotide-bindlng protein (GI) in m e t n ~ of tleulro~lagtom~ X glioma hybrid celia. B~ASemJI98B, 252369-373.

Mogx/y.s TI, ROaEgrS AB: Transforming ~ factor [~ regu la t~ the m e t a ~ l l a m of proteogtycans In bovine cart i la~ organ cultores, J Biol O=,em 1988, 263:12828-12851.

MURC~ G, l IUI.ETSk'Y A, POIRtER GG:. Review: modulat ion o f chromatin structure o f poly.(ADP- rlla*mWI)ation. B~c.hem Ce//B/0/1988, 66:626--635.

MUS~ IS, ~ C, ~ ' ~ JB, MEm.m JP: Acetytcholine receptor.aasodated 43K protein contains co~almatly bound myrtstate. J Ce~ B/~/1988, 107:1113-1122.

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SZTUL ES, CHU TW, STRAU~ AW, RO6L'.~ERG LE: Import of the malale dehydrogena~ precursor by m l t o c h o n d r ~ Cleavage within leader pepllde by matrix protease leads to furmation of Intermediate-sized form. J Bid G~m 1988, 263:12~5--12091.

T&NAXA K, yOme.ML~A T, KL~L~VORI ?,1 Iom~&~ A, LKAI A, • N£SHIGAI M, K.~MEYA.~ K, TAKAGI I".. Protea~mes

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THOMAS G, THO~,.X BA, "I)iOM,~ I . ALTON RG. HRUBY DE, FIa.LER R, T~tOR.'.ZR j: Yeast ~e_.x2 endopeptidase correctly c leav~ a n e ~ prohormone In mammalian cells. Sdeme 1988, 241-~26-231.

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VARRO A, DE.MONaD H, PAU~'EI~ $, GKEGORY tl, YOU,"~G J, DOCKZ~Y GJ: The human gastrin p txmumr. ~ t l o n o f phosphorylated form* and fragments. Bi<~ora J 1988, 256:951-957.

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WAIL~ P.. ~D.RT~ IF: Early processing of prothrombin and factor X by the v i tamin K-dependent carboxylase .JBid Ox, m 1988, 263:9994-10001.

X~EBER IT, MIILER ~L JASKOI~KI ~L LEIS J, SKAI~ ~-%L X~DDA~.R A: Molecular modeling of the HIV-I prote~gse and Its sub*trate b inding •ire. Saence 15~9, 243:92&-930.

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Z]ONOmCK "IF, K~.RRSON ML, I.~t.CSON CC, GE.~a.EN R[~ Genex~ttinn of an active protein-tyrosine from lymphocyte~ by proteoly~is. J Bid Oxyn 1988, 263:19195-19202.

ZU~mRL~'~ A, STONX S, StrAW E: The trynthesis *rod properties of peptidylmethylsulphoninm salts with two cationic residues as potential Inhibltors of p rohormoae processing. Bkxhem J 1988, 256:989-99-1.

Regulation of protein degradation

ABE K, EMOP.I Y, KONDO It, AP~q S, SU'ZL~a K: The Nil 2- t e rmhu l 21 amino a d d residues are not essential for the papain-inhibttory activity of oryzacystatln, a member of the cystatin superfamlly. Expre~ lon of oryzacystatin cDNA aJt~d It.* truncated fragments In ~ o04~ J Biol O~,rn 1988, 263:7655--7659,

AP.~KAWA IL N t S ~ q ~L ~ A: ~2-macroglobulin tralm a protelnase in the mldrt'Blon of its arms. An hnmunoelectron mic ro~op ic •tudy. f Bk3/Ox, m 1989. 264:2350-2356.

ARFLN 5,~t BRAD6HAW RA: Cotran$1ational p roce~ing and • proteIn m o v e r In eukacyotlc cell*. B/0cbem/.~,y

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BRIGOrn M, R~.~mELU F, ZA.Va~O,',I I~ L MO.X'rANARO ~ SPERTI S: Effect o f a~ t r c in ~ rib•some-inactivating proteins on the Interaction of elongation fitctoes with ribosomes. B ~ f1989, 257:T23-727.

BUCKLER AJ, VE ~ ,~O~HXLN GE, I~LLER P,A: Defective T Iympho~°ytes In o ld mice: d imin i th~ ! production o f matu_~ c-myc mhogen e~o~tttfe not attributable to alterations In ~ p t i n a or RNA stability. J lmmuno11988,140:2442-2446.

BL~L%~.N FD, PT&'~C~'E M: Turning Lcro Into a ~ p t i o a a l ~ctiwttor. Co//19~8, 54:191-197.

BtSIXER PE, BOND JS: A latent prOteinam~ In mouse kldmey membranes. Characterization and rr3attion~hlp to meprin. J Bid G~,m 1988, 263:13|19-13426.

CA.~,WBEIL EJ, CAXWBELt. MA: Pe-vicellular proteolysis by neutrophlls In the presence of protetnase Inhlbhors: effects o f •ubattate olmonlzadon. J Ce//B/64 1988,106:667-676.

CH/dNG tt L, DICE .IF: Peptide sequences that tar l~t • proteins fur pnhanced degradation dur ing

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C H ~ CS, BAL~D FJ: Regulation of the breakdown rates o f biotin-containing proteins in Swiss 3T3- L1 cells. B/ochemJ ]988, 251:749-755.

CtL~'.7ORASEK~R $, tD~'v'~Tz" ~ Traaaforming growth f2ctor-~ is a potent inhib i tor of IL-1 induced protels¢ activity and ~ proteoBlycan dLegredation. Btocbgcn B i c ~ Res Commun 1988, 157:1352-1359. V, TOEL~S JW, B.,0Zl-L%,,m A, M.~.Paorr D, ECKER DJ,

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CH~ C, BO,~'~ACLNO JS, yL~.N I.C, IOAL'SNER Rl~ Selective degradation of T cell antlge~ tx~ceptor chains retained in a pre-Golgi compartment. J Cell Eiol 1988, 107:2149-2162.

CIEO~NO~ZR A, FE~EX 5. ~.NOPa D, ElLiS S, HE~SFmO • • A, ARFLN S: Purification and characterization

of arl0nyl-tRNA-protein U'ansfera~ from rabbit retlculocyte~: its involvement in post- m l a t i o t l a l modification and degradation o f acidic Nil a termisti sub*trates of the ublqul t in pathway. J Bid ~ 1~8, 263:11155-11167. [32].

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COOK JR. CHLW J-K: Fnh~neement of transfot'lned cell growth In agar by serinc protease lnhlbltors. J Co//Ph3*/o/1988, 136:188-193.

DAX~ TA, KA~ IE: Resistance of proteIn aud glucose metabolism to Insul in In den•r io ted rat muscle. BiodxTnJ 1988, 254.~67-675.

DOA.'J NP, ~ E R GB: The A - - and B-chah~ of carboxypeptldase 1 from 8ermimted barley ortslnate from a •Ingle precursor polypeptid¢. fBiolG~em 1988, 263:11106-11110.

Dot R, LNOUE K, KOGn~.E ~L SL,~tl S, YUN/~L FL'KAn S, FL~Ja N, Y/qLMA tl, "loBE T: Role of sulphated tyrt~Ine resklue In Influencing the biologic activity of human cholecystoltlnln-33. Bk3d3em B / c ~ Re$ Commun 1988, 153:1209-1213.

DCBf~ S, FISHER JW, POxt'EIL JS: Giyc00ylation at specific •ties of erythropolet in is es.~ntlal for biosynthesis, sec~t lon , and biological function. J Bk3/Ox, m 1988, 263:17516-17521.

DL'PREZ V~ CO KhZT V, DAUaXY-VARSAT A; Dowl3-regulation of high ~r/nt ty Interleukin 2 receptors in a human tumor T cell line. Interleuldn 2 Increases the rate of surface receptor decay. J Eta/¢3x.rn 1988, 263:12860-12865.

EDrrOPaAiz Ubtquittn, prOtein degradation, and dyntmlc neurolmthology. Lancet 1988,1/:319.

EIY, L'~rE~ ItS, ROSEN JM: Both cell substratum regulat ion and hormonal regulation o f miLk protein Bene expression are exerted primari ly at the p o ~ r i p t i o m d level. M~ Ce//Bid 1988, 8:3183-3190.

ELIA MC, MOLq3RI&XAKE EN: Regulation of H2a-$pecific pmteolysis by the hlatonc H3:EM tetramer. J B~/

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DIXON JS,WEBER PL, CROOKE ST: Ubiqultl~ function studied by ~ e m q ~ r i n g . J Biol ~bem 1989, 264:1887-1893.

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Post-transcriptional processes Miscellaneous 1265

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Tg'qAKA K, ICHnI~A & Involvement of ptoteasomes (multicatalytic p ro te ina~) In KI'P-dependent p m t e o l ~ i s In rat reticulocyte extracts,/T_B$ Lea 1988, 236.159-162.

TAYLOR AK, WALL l~ Selective retnoval of ~ e a v y - d m l n #ycmyla t ion sites causes immunoglobul in A desradation and reduced secretion. M0/Cell Bi0/ 1988, 8:4197-4203.

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Y&~UTA O, L\'DS.,61TH IS: Metsbollc fates of yolk proteins dur ing emb~-oBenesls In arthrolmds. 1X~ Growth/~ffer 1988, 30:337-346

YOKOrA Y, KATO K]~ Degradation of yolk proteins In sea urchin eggs and embryos. Ce//D~er 1988. 23:191-200.

Miscellaneous

AC~ILV, AN EJ, SAX~';A SK, U~PaOI N: ~t-sarcIn causes a specific cut In 28 S rRNA when mlcrolnj¢cted Into Xenopus oocytes, y Bi0/ Clrm 1988, 263:17076-17083.

ALGAIER J, I~IES I~1: The effects of dimethyl sulfoxide on the kinetlc~ o f tubulIn ~ b l y . B/x2n'm B/c/Rr)~ Acta 1988, 9fet:235-243.

B.~"roN JS, V£-;0~x3rcr DL, tlEAC_X3CX DH, COFF~.'; JA, TRYGG KA: Mlcrotubule assembly Idoctio;: chamg~--s wtth solution conditions. BiocbemJ 1988, 247:505-511.

BERKttOUT B, AIARCON B, "I'ERHOgSI" C: Transfection o f g e n ~ encoding the T cell receptor-associated CD3 complex Into COS ceils re0ults in ass¢lnbly of the macromolecular structure. ] B~/ 1988, 2638528-8536.

BOGGS BA, b ~ gM, LOEB 12,1, COOK R, CAB~L F: Mutations affecting assembly of ~tobuLLq localize to a region near the carboryl termInus. JBtolC2rm 1~8, 263:14566-14573.

BOUCH~ M, GOLDFLX'E SM, FtsC142daN D& Pmttranslational Incorporation o f contractile proteins into myofibrlls In a cell-free system. J Cell Bi0/1988, 107:587-596.

BOL~.'x~ B, F1Lt\xl~q S, C.ASSLX~RIS L SALMON EI~. High hydrostatic pt 'e~ure effects In vtvo: chanses In cell morphology, mlcrotubule aascmbly, and actin ofs~o/zatinn. Ce~ 3f~t.,~ Cytoskeleton 1988, 10~O-3~0.

BP~N.'NZR SL, ZID1~CK .~, GRIFFITIt ~ RecA protein self- assembly. Multiple discrete aggregation states. ] 310/B/O/1908, 204.959-972.

BL"d.EID NJ, FRELM&N RB: D~fectlvc co-translatioIMd formation of disulphide bonds In protein disulphide- Isomerase-ddficlen t m i ~ [letter|. 1Vat,re 1988, 335:649--650.

C.&~tPO6 N, PAIAU J, TORRENT M, LLa~EXXD I~ Signal recognition-like particles are present In maize. J B~/Ox, m 1988, 263.9646-9650.

DA',~ JS: Assembly processes In vertebrate skeletal thick filament formation. Annu Rev Bicl~s Biq~rl Ox, rn 1988, 17:217-240.

DONATO P~ Calcium-independent, pH-regulated effects of S-100 proteins on a s s e m b l y - d ~ b l y of brain microtubule protein tn v/ere. J Bt~/Ox, m 1~8, 263:106-110.

Dtrf'RESNZ I~ DES~OOIXS hi, BOURGAUI.T C, GICQUAL'D C, DUB~ F: Relationships betwora Intracellulxt" pH. proteIn synthesis, aJad actin assembly dur ing parthenogenetic activation of sea urchin eggs. B/0cbem Ce//B~/1988, 66:780.

ttAs.~ts E, ItaGGL~ E, OtEN J-W, UM/3.~GER H~: Translational coupling between the ffvD and Ht,A 8~nes O f E.~benk:b/a co/£ f B a c ~ 1 ~88, 170:4798--4807.

IIEUSER JE, KELN J: Deep-etch visualization of plot©Ins Involved In clathrin assetnbly. J CeU Bi0/1988, 107:877~86

I~X'~E S, ODA K, IKEt LM~A y: Biosynthesis, ~ b l y and secretion of fibrogen In cultured rat hepatocytes. Bio6bemJ 1988, 251:373-378.

L'qAGA~ M, GON'DA 3(, bt~TSb"/AXt~ hi, NISI{IZAWA K, NISIII Y, SATO C: Intermediate filament reconstltution /n v/ere. The role o f ph0ophorylation on the asaembly-disassembly of detrain. J Bh3/Oxen 1988, 263:5970-5978.

JAPA S, BEATFIE DS: Cytochrome b Is necessary fur the assembly of subunh VII in the cytochrome & c 1 complex of yeast mhochondrla. Arch Biocbem B/0/~'s 1988, 264:231.

KAEI2~ DM, NgSON JI I: Methotrexate-induced anpllfiealton of the bovine httroptn genes in Chineoe hamster ovary cells. Relative concentratinn o f the ct and [~ubunlts determines the extent of b e t t e r assembly. f Biol ~ 1988, 263:6344-6351.

KOT&',I S, IKAI A, KAWAI G, ~t~EKAWA S, YOKOY&%~ S, SAKM ti: Mlcrotubule-assembly Inhibitor protein ---Its distribution, lo,'-all,~tdon and physlcochemlcal properties. EurJ B:b¢/~rn 1988, I76:573-580.

I~'¢DOUq NT, YL'q XM, CAPILJ, JD, TUCKER F~': A c o ~ heptamer u p s ~ of the IgH promoter region octamef can be the slte e r a coordinate protein-DNA Interactinn. ?;ude/c.4ct2/s Res 1988, 16:5503-5514.

LIPP J, DOBBERSrELN B: Signal and membrane anchor functions overlap in the type H membvane prote Ire ITCAT, J Ce//B;~/1988, 106:1813-1820.

I~LL',~ KG, JEN.%~ RJ, KRISt~AMY S: Of'actor proteins in the assembly and expressloo of blood clotthag enzyme complexes. Annu Rev Euxbem 1988. 57:915-956-

/~thvi'~l DP, SOL~Yr RE, DIS'IXFA.NO PS, LOWRY O11, CAKIXR JG, JOtgq.~ON F~k| JR: Inhibi t ion of protein synthesis and RNA synthesis prevent neuronal death caused by nerve 8rowth fitctor deprivation. J Ce// Bib/1988, 106:829-844.

M~yrvm~as LC, NO.MUP.A/~ Feedback regulation of the spc operon In ~ ~ translational coupling and mRNA processing. J Bacter:~ 1988, 170:4484-4492.

McCIAL'; ~1L FOSS K: t '~han#ng the Identity of a tRNA by IntroducIng a G-U wobble pair near the 3" accepter end. S¢/en~ 1988, 240:793-795.

MORGEILN ~L P A ~ N M, I IARDLNGH£M TE, IIEEXZGARD D. F~;GEL J: ~ proteo#ycans assembly with hyaluronate and l ink protein a.s studied by electron m l ~ o p y . Bioclx, m J 1988, 253:175-185.

MLVOL~LAI"SU 1", N~SH1KAWA K, NE,~tOTO F, KUOILNO y, h~SttL~IL~A S, M~AZAWA T, YOKOY~-~t~ S: Codon and amino-acid specllicttles of a transfer ILNA are both converted by a single post-trsnscelptional modification [lettec]. Nature 1988, 336A79-181.

NELSON KK, GR/~'q I ~ Splice site selection and rlbonucleoproteIn complex assembly dur ing tn ~ pf¢-mlLNA splicing. Genes De*, 1988, 2319-329.

NGtY/~N Qv, H~tPHr.EYS RE: Tlme course of intraceHular aasoclatlons, proce*~ing and cleavages of I x forms and class H major histocompattbll i ty complex molecules, J B/0/ OTem 1989, 264:1631-1637.

NOXrO~3" V, Nmgtt,.Us Ktt: Assembly of the 30S subunt t from ~ c o H ~ m e s occur* via two assembly domains which are Inhlated by $4 and S7. Bioclx,mistry 1988, 27:7051-7055.

OSTMAN A, RAIL L tt~XLXtJ, OtER A, WOS.~LvrEAD ~t~, COW D, V/d£N2UEtA P, BETSttOLa-Z C, WESTEK~tt2K B, t'IELDLN Ctt: Synthesis and a.~aa~mbly of a functionally active recombinant platelet-dectved 8rowth factor AB hcterodimer. J B/~/Chem 1988, 263:16202-162~.

Pg'q X-X, WARE BP~ Actin assembly by l i thium ions. Bi~b)*J 1988, 53;11-16.

PARKER KJh BRLr2IK JP, STEITZ Jp¢ An ~ t~ ro Intt~ra~tton between the human U3 snRNP and 28S rRNA aequences near the ~t~arcin site. Nuc2efi: Act2/s Res 1988, 16:10493.

PETER ME, WrrrM&\,'N I.mSOLD B, Sp~',XL M: Attinlty labeling of the GDP/GTP bInding site In Tbermus l~ . rmop~/us elongation factor Tu. B/oc/x,m/stry 1988, 27.9132-9138.

POPOFF bfl~,, BOQL~'I" P: C ~ m ~ o r r a e toxin b a blmwy toxin which ADP-rlbo~-late~ cellular actin. Bicxl~Tn Biqob)~ Res ~rnmun 1988, 152:1361-1368.

R~MO,-,~ BC, RC36K~H ~ A chemical modilica- t i o n / I n t ~ n c e study of y e ~ t pre-mRNA splice~ome assembly and splicing. Genes Dev 1988, 2:428-439.

S~OlS S, I~cr~v E, ~;ZSEa LA: Effect of best shock on K.NA meml~l i sm In HeLa cells. J Cell Plg~io11988, 135377-386.

Sf~PHLN B, ~ . R I~ ROSB~H M: A U1 S~d~.NA.: pt~- mRNA base palrtn 8 Interaction IS required early In ye~mt spUceosome ~ b t y but d o ~ not uniquely define the 5" cleavage site. EMBOJ1988, 7:2533-2538.

1266 Post-transcriptional processes Miscellaneous

S ~ r ~ l H, Ste.~ttw, A y: Functlona] doma/J~ of the P-N'A component of r ibonucleas¢ P ~ e d by chemical peoblng of mutan t RNAs. F~BOJ 1983, 7:3817-3822.

Som~Lm~o 5, T u ~ GK, G m z DCr. Purif i~t lot t and ~ e r l z a t i o n of a rtbottuchm.~e f rom h u m a n liver.JBtol Oxom 19~. 263:1612%16131.

ST ~ DK, R ' ~ SM. l~om3~.,~ JF, V~J~E Bh Angiogenln abolishe~ cell-free proteIn w/-nthe~ls by specific r4bonucleolytic Inactivation of 40S rlbooomes. B:~2x, m/stry 1988, 27:7263-7268.

STLPt~'~ EB, CO,~W&x~ RW: Assembly of ~nlm~J at cellutaf membranes . Annu Re*, Microbio119~8, 42=489-516.

' , ~ J C . I~ws CL ~co3.~a P,B: Heat-stable mlcrotubule proteIn MAP.I IMmis to mlcrotubule~t and tnduce~ mlcrotulmle assembly. FEB5 Leu 1988, 232:159-162.

VI~HL? D.t.L BL~;~pf V: ClathrLq~oated vesicle assembly polypcptlde*: phy~|od peopertles and reconst l tut inn studies wi th bra in membranes . I Ce//Bio/1988, 10639-50.

vtRs11LT D~L BLN.%XTF V: Clathrl~.coated vesicle assembly polypeptidc~: physical propert ies and reconst i tut loa sttzdles wi th ~ m e m b r a n e s . J Ce/ /B~ 1988, 10639-50.

WAGN'L~ PD, VU N-I~. Filament assembly and ft 'gulatloo of the actin-acflvated ATPase act ivi ty of thymus myosin. B t ~ m ~ ' r y 19~8, 27.6236-6242.

WOIL,",X~ DA. SCHEL~3'.~'q R, CATIXRALL W.A: Sodium channel expre~lot t and assembly dur ing development of retinal ~no=lion cells..Neuron 1988, 1:727-737.

WU C, FP.IED.~*.~.'~ R, OIL.~G AE: Analysis o f the assembly of lamlnln and the Laminin-entactin complex

I ~ |amlnln ¢~E{J[I $~X~¢~¢ ~a~tOID(xJon.1] and p o l y c l o ~ antibodies. B'mc~*r~c~y ]9~, 27:8780-87~.

YAFt~ ~,~, F~-R G~, STEP~\~Q~rr EL Tr~nslation of ~-~ubulin mL"qA i n v l~ 'o generates mnltlple molecular forms.JBtolC~,m 1988, 263:16023-16031.

ZA~OW~ D. ~CKL',~ ~.~ A functionally redundant downstream sequence ha SV40 late pre-ml~N'A is required for mRNA 3 ' -~xl formation and for assembly of a precleavage complex in t4trtx J B : ~ / ~ 19~8, 263~57B0-$788.

Serenty-kUodadton heat shock proteins and an additional component f rom retlculocyte Iysate st imulate Import o f M l 3 pt-ocoatt protein Into m t ~ m e s . E.ILBOJ 1988, 7;2875-2880.

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Post-transcriptional processes

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