Poster Contributions Pharmaceutical Biology P B1 Arampatsis, C., Länger, R. TAXONOMIC STUDIES ON PIMPINELLA SAXIFRAGA S.L. (APIACEAE) P B2 oral Barleben, L., Ma, X., Koepke, J., Peng, G., Michel, H., Stöckigt, J. X-RAY ANALYSIS OF STRICTOSIDINE GLUCOSIDASE, A CENTRAL ENZYME

OF INDOLE ALKALOID BIOSYNTHESIS P B3 Bodensieck, A., Gruber, A., Bauer, R. PHYTOCHEMICAL INVESTIGATIONS ON LEAVES OF PETASITES ALBUS P B4 Bucar, F., Asres, K., Gibbons, S., Hana, E., Kraxner, C., Allmaier, M. ELUCIDATION OF ANTI-INFLAMMATORY COMPOUNDS FROM MELILOTUS

ELEGANS P B5 Červenka, F., Víchová, P., Kolečkář, V., Pour, M., Opletal, L., Jahodář, L. EVOLVULUS ALSINOIDES – PHARMACOBOTANICAL EVALUATION P B6 oral Chobot, V., Vytlačilová, J., Jahodář, L., Opletal, L. PHOTOTOXIC ACTIVITY OF THIOPHENE POLYACETYLENE (E)-1-[5-(HEPT-

5-EN-1,3- DIYNYL)-2-THIENYL]ETHAN-1,2-DIOL P B7 Funke, I., Melzig, M. F. INHIBITION OF α-AMYLASE ACTIVITY BY DIFFERENT PHENOLIC

COMPOUNDS P B8 oral Godejohann, M., Seger, C., Tseng, L.-H., Spraul, M., Girtler, A., Sturm, S.,

Stuppner, H. IDENTIFICATION OF IRIDOID GLYCOSIDE REGIOISOMERS FROM

HARPAGOPHYTUM PROCUMBENS USING A LC–DAD–MS/SPE–NMR HYPHENATION AS DEREPLICATION TOOL

P B9 Hadžifejzović, N., Petereit, F., Nahrstedt, A. ISOLATION OF PHENOLIC COMPOUNDS FROM THE ARIAL PARTS OF

RUSCUS ACULEATUS L. (RUSCI HERBA) P B10 Henke, K., Melzig, M. F. INVESTIGATION OF SELECTED NATURAL COMPOUNDS AS INHIBITORS OF

THROMBIN ACTIVITY P B11 Klečáková, J., Škorpíková, M., Opletal, L., Jahodář, L. BIOLOGICAL ACTIVITY OF MACROMYCETES P B12 oral Jenett-Siems, K., Frölich, S., Schubert, C., Bienzle, U. ANTIMALARIAL ACTIVITY OF CHALCONES FROM HOP AND THEIR

INFLUENCE ON HEME-DEGRADATION P B13 Länger, R., Demir, H., Ölzant, S. ULTRASTRUCTURE OF THE TESTA OF THE SEEDS OF CASSIA

ANGUSTIFOLIA AND C. SENNA P B14 oral Kolečkář, V., Opletal, L., Polášek, M., Jahodář, L., Jun, D. ASSAY OF RADICAL SCAVENGING ACTIVITY OF PLANTS OF FAMILY

ASTERACEAE AND CHICORIACEAE: SCREENING STUDY USING SIA AND ON-LINE HPLC METHOD

26

Poster Contributions P B15 Li, P., Bakowsky, U., Yu, F., Muecklich, F., Lehr, C. M. SURFACE PATTERNING BY INTERFERENCE LASER ABLATION AFFECTS

THE EXPRESSION OF CELLULAR SIGNAL AND ADHESION MOLECULES P B16 Martin, J., Dušek, J., Dušková, J., Poustka, F. EFFECT OF PHYTOHORMONES ON SCUTELLARIA BAICALENSIS CALLUS

CULTURES P B17 Mittermayr, R., Guo, Y., Saukel, J., Hiessböck, R., Galla, G., Ehrendorfer, F. MOLECULAR BIOLOGICAL, MORPHOLOGICAL AND PHYTOCHEMICAL

INVESTIGATIONS OF NATURAL HYBRIDS BETWEEN SPECIES OF DIFFERENT ACHILLEA-SECTIONS.

P B18 Möller, M., Weiss, J., Wink, M. EMETINE MODULATES P-GLYCOPROTEIN FUNCTION AND UP-REGULATES

IT'S M-RNA EXPRESSION IN CACO-2 CELLS P B19 Odonchimeg, B., Schwaiger, S., Seger, C., Ellmerer, E. P., Berger, A.,

Stuppner, H. PHYTOCHEMICAL AND PHARMACOLOGICAL INVESTIGATIONS OF

FILIFOLIUM SIBIRICUM KITAM. P B20 Ölzant, S., Stögmüller, M., Länger, R. SEM INVESTIGATIONS OF CALCIUM OXALATE CRYSTAL SAND OF

MEDICINAL PLANTS P B21 Oleski, A., Melzig, M. F., Lindequist, U. SCREENING OF MEDICAL PLANTS FOR THEIR INHIBITORY ACTIVITY

AGAINST THE ENZYMES NEP AND ACE P B22 Poustka, F., Roytrakul, S., Martin, J., Dušek, J., Dušková, J., Verpoorte, R. ACTIVE TRANSPORT OF AJMALICINE INTO VACUOLES OF

CATHARANTHUS ROSEUS P B23 Reznicek, G., Lepuschitz, K., Kropfitsch, L., Glasl, S., Werner, I. QUANTITATIVE DETERMINATION OF THE PROAZULENES IN ACHILLEA

SPECIES USING APCI-MASS SPECTROMETRY P B24 Rimakova, J., Tumova, L., Martin, J., Dušek, J. ELICITOR-LIKE EFFECTS OF LOW-ENERGY ULTRASOUND ON

GLYCYRRHIZA GLABRA L. CALLUS CULTURE P B25 Saukel, J., Mittermayr, R., Guo, Y., Rauchensteiner, F., Nejhati, S.,

Ehrendorfer, F. MOLECULAR BIOLOGICAL, MORPHOLOGICAL AND PHYTOCHEMICAL

INVESTIGATIONS OF SPECIES FROM DIFFERENT ACHILLEA-SECTIONS. P B26 Schnitzler, M., Petereit, F., Nahrstedt, A. FLAVON-C-GLYCOSIDES AND TARTARIC ACID DERIVATIVES FROM THE

BRAZILIAN MEDICINAL PLANT ECHINODORUS GRANDIFLORUS SSP. AUREUS

27

Poster Contributions P B27 Schwaiger, S., Sturm, S., Wiesbauer, B., Seger, C., Ellmerer, E. P., Stuppner, H. SIMULTANEOUS DETERMINATION OF FLAVONOID- AND CAFFEIC ACID

DERIVATIVES OF EDELWEISS (LEONTOPODIUM ALPINUM CASS.) BY LC/DAD AND LC/MS

P B28 Streit, B., Bricman, Y., Bucar, F. FLAVONOIDS FROM FRUITS OF JUNIPERUS COMMUNIS AS INHIBITORS

OF PLATELET 12-(S)-LIPOXYGENASE P B29 Werner, I., Mucaji, P., Presser, A., Glasl, S., Reznicek, G. A NEW DIMERIC SESQUITERPENE LACTONE AND A SECOGUAIANOLIDE

FROM ACHILLEA SP. P B30 oral Woll, J., Ruppert, M., Giritch, A., Stoeckigt, J. A NOVEL VIRUS-BASED PLANT EXPRESSION SYSTEM FOR GENES OF

ALKALOID BIOSYNTHESIS Pharmaceutical Chemistry P C1 Altenkämper, M., Kettler, K., Wiesner, J., Esteva, M., Dahse, H.-M., Ortmann, R.,

Bontempi, E. J., Jomaa, H., Schlitzer, M. FARNESYLTRANSFERASE-INHIBITORS AS ANTI-PROTOZOIC AGENTS P C2 oral Ambrożak, A., Eger, K., Gütschow, M. PHTHALIMIDO- AND TETRAFLUOROPHTHALIMIDOBARBITURIC ACIDS AS

POTENTIAL ANTIANGIOGENIC AGENTS P C3 Arnold, C., Hörnig, M., Albert, D., Steinhilber, D., Werz, O. INDUCTION OF LEUKOTRIENE BIOSYNTHESIS BY DIGLYCERIDES: A NEW

ROUTE FOR ACTIVATION OF 5-LIPOXYGENASE P C4 oral An, P. K., Rack, C., Matusch, R. FISHING OF LIGANDS WITH HUMAN THROMBIN IN LIBRARIES P C5 Banekovich, C., Matuszczak, B. INVESTIGATIONS OF THE HYDROLYTIC CLEAVAGE OF NSAID-

TETRAACETYLRIBOFLAVIN CONJUGATES P C6 Bannwitz, S., Müller, K. NOVEL LAPACHO COMPOUNDS: NAPHTHO[2,3-b]THIOPHEN-4,9-DIONES

AS POTENT INHIBITORS OF KERATINOCYTE GROWTH P C7 Bednarski, P. J., Zielzki, M., Grünert, R., McKay, F. S., Sadler, P. J. PHOTOACTIVATION OF DIAZIDO-Pt(IV)-DIAMINES TO CYTOTOXIC SPECIES P C8 oral Beitz, E., Pavlovic-Djuranovic, S., Schultz, J. E. AQUAGLYCEROPORINS OF PATHOGENIC PARASITES: TARGET AND

VEHICLE FOR CHEMOTHERAPY? P C9 Bennesch, K., Duchstein, H.-J. CAPILLARY ELECTROPHORESIS AS AN ANALYTIC TOOL FOR

METABOLISM IN SALIVA P C10 Botzki, A., Buschauer, A., Dove, S. STRUCTURE-BASED LIGAND DESIGN FOR BACTERIAL HYALURONIDASES

28

Poster Contributions P C11 Bracht, K., Boubakari, Bednarski, P. CORRELATION BETWEEN THE IC50-VALUES OF 19 STANDARD

ANTICANCER AGENTS AND GLUTATHIONE IN HUMAN CANCER CELL LINES

P C12 Braun, S., Botzki, A., Schneider, L., Bernhardt, G., Buschauer, A. STRUCTURE-ACTIVITY RELATIONSHIPS OF BENZOXAZOLE-2-THIONES AS

INHIBITORS OF BACTERIAL HYALURONIDASE P C13 Briel, D. 1,2-DITHIOLES AND 1,2,4-DITHIAZOLES- NOVEL SYNTHESIS AND

INVESTIGATION OF ANTIBIOTIC ACTIVITY P C14 oral Breuning, A., Schiller, M., Kaeppler, U., Jenke, F., Degel, B., Vicik, R., Stiefl, N.,

Baumann, K., Schmuck, C., Ziebuhr, J., Schirmeister, T. SCREENING OF ELECTROPHILIC COMPOUNDS AS POTENTIAL

IRREVERSIBLE INHIBITORS OF CORONAVIRAL MproS P C15 Busch, S. V., Gust, R. NON STEROIDAL ESTROGENS ON ERa AND ERb WITH 1,2-DI-ARYL-1,2-

DIAZIDOETHANE STRUCTURE P C16 Bulicz, J., Baumert, D., Müller, C. E., Heber, D. SYNTHESIS AND PHARMACOLOGY OF AMINO-SUBSTITUTED PYRIDO[2,3-

d]PYRIMIDINES AS POTENT AND SELECTIVE A1 AND A2a ADENOSINE RECEPTOR ANTAGONISTS

P C17 Buss, U., Bluhm, U., Heber, D., Hennies, H., Sundermann, B., Clement, B. PYRIDO[1,2-a]PYRIMIDINES: ACTIVITIES OF A NEW CLASS OF SELECTIVE

NO-SYNTHASE INHIBITORS P C18 Chlupáčová, M., Opletalová, V., Silva, L., Buchta, V., Kuneš, J. BIOLOGICAL ACTIVITY OF 3-ALKYLSULFANYL- AND 3-ARYLSULFANYL-1-

PYRAZIN-2-YLPROPAN-1-ONES P C19 Dahse, T., Listing, M., Fleck, C., Oelschläger, H. SYNTHESIS OF IDENTIFIED AND POSTULATED OE9000 METABOLITES P C20 oral Christ, K., Wiedemann, I., Rüttinger, H.-H., Sahl, H.-G., Bendas, G. THE APPLICATION OF BIOSENSOR TECHNIQUES TO MONITOR THE

MOLECULAR MECHANISMS OF LANTIBIOTICS P C21 Degel, B., Staib, P., Morschhäuser, J., Schirmeister, T. cis-CONFIGURED PEPTIDYL EPOXIDES AND AZIRIDINES AS INHIBITORS

OF SAP 2 FROM CANDIDA ALBICANS P C22 oral Claus, R. A., Berbig, L., Loesche, W., Stiefel, T., Dawczynski, H., Deigner, H. P.,

Russwurm, S., Reinhart, K. MODULATORY EFFECTS OF SELENATE ON GENE EXPRESSION

PATTERNS IN STIMULATED MONONUCLEAR CELLS P C23 Deigner, H. P., Wuestholz, A., Le, H. P., Kinscherf, R., Claus, R. A. CERAMIDE AND NOVEL CONFORMATIONALLY CONSTRAINED ANALOGS

MEDIATE REVERSE TRANSLOCATION OF PKC-a

29

Poster Contributions P C24 Dettmann, S., Gust, R. SYNTHESIS AND ESTROGEN RECEPTOR INTERACTION OF

BENZIMIDAZOLES P C25 Diwischek, F., Holzgrabe, U. ELUCIDATION OF THE STEREOCHEMISTRY OF 1,2,6-TRIMETHYL-4-

PIPERIDONE P C26 Doležal, M., Buchta, V., Králová, K. CARBOXAMIDE MOIETY AS A BRIDGING LIGAND IN SERIES OF

PYRAZINAMIDE ANALOGUES, SYNTHESIS AND EVALUATION P C27 Domeyer, D., Scior, T., Laufer, S. DOCKING OF TRI- AND TETRA- SUBSTITUTED IMIDAZOLES INTO THE ATP

BINDING SITE OF p38 MAP KINASE P C28 Eisenmann, M., Steuber, H., Zentgraf, M., Klebe, G., Schlitzer, M. STRUCTURE-BASED DRUG DESIGN OF ALDOSE-REDUCTASE-INHIBITORS P C29 Eisenschmidt, A., Richter, M., Gyémánt, N., Molnár, J., Hilgeroth, A. TRANSPORTER SPECIFIC PROPERTIES OF HIV-PROTEASE IN-HIBITOR

DMP 323: IN SITU AND IN VITRO CHARACTERIZATION P C30 Elsinghorst, P. W., Gütschow, M. N-ACYLPYRROLIDIN-2-ONES: POTENTIAL INHIBITORS OF SERINE

PROTEASES AND SERINE ESTERASES P C31 oral Ermert, J., Olma, S., Hamacher, K., Coenen, H. H. IMPROVED SYTHESIS OF THE NOREPINEPHRINE ANALOGUE N.C.A. 4- [18F]FLUOROMETARAMINOL P C32 Enzensperger, C., Mohr, P., Schmalwasser, B., Wiecha, P., Lehmann, J. MONOHYDROXYLATION ENHANCES THE AFFINITY OF BENZ[d]INDOLO[2,3-

g]- AND DIBENZ[d,g]AZECINE-TYPE DOPAMINE RECEPTOR ANTAGONISTS P C33 oral Fáková, H., Pour, M. SYNTHETIC STUDIES ON UNCININE P C34 oral Foltýn, M., Šatínský, D., Polášek, M. DETERMINATION OF CHOLINESTERASE INHIBITORS BASED ON MICRO–

SEQUENTIAL INJECTION-LAB ON VALVE TECHNIQUE. PART I: OPTIMIZATION OF THE REACTION CONDITIONS

P C35 Fankhänel, M., Fellner, S., Spruß, T., Bernhardt, G., Buschauer, A. IMPACT OF ELACRIDAR AND TARIQUIDAR ON THE DISTRIBUTION OF

PACLITAXEL IN NUDE MICE P C36 Friedrich, F., Girreser, U., Rostaie-Gerylow, M., Wolschendorf, U., Heber, D.,

Clement, B. PYRIDO[1,2-a]PYRIMIDINE: SYNTHESIS OF A NEW CLASS OF SELECTIVE

NO-SYNTHASE INHIBITORS P C37 Fritzsche, J., Alban, S., Schumacher, G., Bendas, G. INVESTIGATION OF P-SELECTIN BLOCKING SUBSTANCES AS PROMISING

THERAPEUTIC AGENTS

30

Poster Contributions P C38 Gabriel, B., Görlitzer, K., Wiesner, J., Jomaa, H. THIENO[3,2-c]QUINOLINES – SYNTHESIS AND INVESTIGATION OF

ACTIVITY AGAINST MALARIA P C39 Geiger, C., Zelenka, C., Wünsch, B. NOVEL к-RECEPTOR-AGONISTS: STEREOSELECTIVE SYNTHESIS OF

BRIDGED PIPERAZINE-DERIVATIVES P C40 oral Globisch, C., Pajeva, I., Wiese, M. STRUCTURE-FUNCTION MODELS OF MULTIDRUG RESISTANCE P-

GLYCOPROTEIN P C41 Ghorai, P., Kraus, A., Götte, C., Bernhardt, G., Dove, S., Reiser, O., Seifert, R.,

Elz, S., Buschauer, A. NG-ACYLATED IMIDAZOLYLPROPYL GUANIDINES: A NOVEL CLASS OF

HISTAMINE H2 RECEPTOR AGONISTS P C42 González, C. M., Gütschow, M. HPLC INVESTIGATION ON ACYLATING INHIBITORS OF SERINE

HYDROLASES P C43 Gößnitzer, E., Amon, A., Wendelin, W. 2-(4-ALKYL- AND 4-ALKENYL-2-IMI-DAZO-LIN-2-YL)-1,2,3,4-

TETRAHYDRO-ISO-QUINO-LINES AS NEW-TYPE ANTIMYCOTIC AGENTS P C44 Graf, M., Galera García, R., Wätzig, H. PROTEIN ADSORPTION IN FUSED SILICA AND POLYACRYLAMIDE-COATED

CAPILLARIES P C45 Gross, D., Bernhardt, G., Buschauer, A. PLATELET-DERIVED GROWTH FACTOR RECEPTOR MEDIATED

PROLIFERATION OF HUMAN GLIOBLASTOMA CELLS: IMATINIB LACKS ANTIPROLIFERATIVE ACTIVITY

P C46 oral Hamacher, A., Hoefgen, B., Lehmann, J., Kassack, M. U. CHARACTERISATION OF CONDENSED AZECINE DERIVATES AS

DOPAMINE AND SEROTONIN ANTAGONISTS BY FUNCTIONAL AND BINDING ASSAYS

P C47 Hallmen, C., Wiese, M. HOMOLOGY MODELLING OF THE ADENOSINE A3 RECEPTOR AGONIST

BINDING SITE P C48 oral Handzlik, J., Maciąg, D., Pertz, H. H., Jähnichen, S., Bednarski, M., Filipek, B.,

Kieć-Kononowicz, K. INFLUENCE OF SOLUBILITY ON a1-ADRENOLYTIC PROPERTIES OF

ANTIARRHYTHMIC PHENYLPIPERAZINE PHENYTOIN DERIVATIVES P C49 Hamoudová, R., Pospíšilová, M., Spilkova, J. DETERMINATION OF PHENOLIC COMPOUNDS IN HYPERICUM

PERFORATUM BY ON-LINE COUPLING OF ITP-CZE P C50 Hartung, B., Riemann, D., Rothe, U., Jahreis, G., Zeisig, R., Bendas, G. LIPOSOMAL TARGETING OF AMINOPEPTIDASE N AS A NOVEL APPROACH

FOR AN ANTIANGIOGENETIC THERAPY

31

Poster Contributions P C51 Hauser, D. R. J., Domeyer, D. M., Scior, T. R. F., Laufer, S. A. SYNTHESIS AND BIOLOGICAL EVALUATION OF ADENINE-LIKE ATP-SITE

DIRECTED INHIBITORS OF PROTEIN KINASES P C52 Havlíková, L., Matysová, L., Nováková, L., Solich, P. DEVELOPMENT OF HPLC METHOD FOR DETERMINATION OF

DEGRADATION PRODUCTS OF PHARMACEUTICALS IN GELS P C53 Heidler, P., Zohrabi-Kalantari, V., Larsen, T., Link, A. O-ALKYL-ISOUREAS: A NOVEL CLASS OF ACTIVATING REAGENTS FOR

THE KENNER SAFETY-CATCH LINKER P C54 Heller, E., Holzgrabe, U. MICROWAVE-ENHANCED HYDROGENATIONS OF INTERMEDIATES OF

HIGH POTENTIAL DRUGS USING HYDROGEN GAS P C55 Hoechstetter, J., Bernhardt, G., Wittmann, H.-J., Buschauer, A. PH-DEPENDENT DIFFERENCES IN THE MECHANISM OF HYA-L-URONAN

DEGRADATION BY TESTICULAR HYALURONIDASE P C56 Hödl, C., Strauss, W. S. L., Sailer, R., Kunert, O., Seger, C., Steiner, R.,

Haslinger, E., Schramm, H. W. DEVELOPMENT AND BIOACTIVITIES OF NOVEL PROGESTERONE

RECEPTOR POSITIVE BREAST CANCER THERAPEUTICS P C57 Hoerr, V., Holzgrabe, U. CHEMICAL, PHYSICAL AND BIOLOGICAL ASPECTS FOR REPRODUCIBLE

CE OF MICROORGANISMS P C58 Hoffmann, R., Gust, R. PYRROLES: NEW LIGANDS FOR THE ESTROGEN RECEPTOR P C59 Hofinger, E., Bernhardt, G., Parthier, C., Rudolph, R., Buschauer, A. EXPRESSION AND IN VITRO FOLDING OF RECOMBINANT HUMAN

HYALURONIDASE HYAL-1 P C60 Holas, T., Klimentová, J., Vávrová, K., Šíma, M., Hrabálek, A. INFLUENCE OF THE STRUCTURE OF CARBAMIC ACID SALTS ON THEIR

TRANSDERMAL ENHANCING ACTIVITY P C61 Hrubanová, S., Farsa, O., Goněc, T. THE SYNTHESIS OF 2-OXO-1-AZACYCLOALKYLMETHAN-SULFONANILIDES

FOR COGNITIVE ENHANCEMENT P C62 Hüfner, A. SYNTHESES OF ANALOGA OF NATURALLY OCCURRING HYDROXY FATTY

ACIDS P C63 Jampílek, J., Chlupáčová, M., Doležal, M., Kráová, K. QUINALDINE DERIVATIVES AND THEIR HERBICIDAL ACTIVITIES P C64 Janßen, N., Horstkötter, C., Blaschke, G. COMPARISON OF LAMP VS. LASER-INDUCED FLUORESCENCE

DETECTION IN CAPILLARY ELECTROPHORESIS OF HUMAN URINE SAMPLES

32

Poster Contributions P C65 Jenke, F., Schirmeister, T. N-ALKYLATED AZIRIDINE CARBOXYLATES AS NEW BUILDING BLOCKS

FOR INHIBITORS OF CYSTEINE-PROTEASES P C66 oral Kaiser, A., Moritz, E., Seidensticker, S., Gottwald, A., Maier, W., Hörauf, A.,

Njuguna, J. T. THE EFFICACY OF INHIBITORS INVOLVED IN SPERMIDINE METABOLISM

IN PLASMODIUM, ANOPHELES, AND TRYPANOSOMES P C67 Kaeppler, U., Stiefl, N., Baumann, K., Ziebuhr, J., Schirmeister, T. ETACRYNIC ACID AMIDES AS NON-PEPTIDIC INHIBITORS OF PARASITIC

AND VIRAL CYSTEINE PROTEASES P C68 Kavalírová, A., Pospíšilová, M., Prokelová, I., Polášek, M. CZE WITH INDIRECT PHOTOMETRIC DETECTION FOR ANALYSIS OF SOME

POLYOLS IN INFUSION SOLUTIONS P C69 Kieć-Kononowicz, K., Drabczyńska, A., Müller, C. E., Schumacher, B., Zobnina,

W., Karolak-Wojciechowska, J. LIGANDS OF THE ADENOSINE A1/A2A RECEPTORS P C70 Kirsch, R., Oelschläger, H. KINETIC BEHAVIOR OF DEGRADATION PRODUCTS OF

NORETHISTERONE® 1MG DURING STABILITY TESTS P C71 Klimentová, J., Holas, T., Hrabálek, A., Palát, K. TRANSKARBAM 12 AND ITS ANALOGUES OF THE POLAR HEAD GROUP –

STRUCTURE AND ACTIVITY RELATIONSHIPS P C72 Klimundová, J., Sklenářová, H., Solich, P. DETERMINATION OF LIDOCAINE AND PRILOCAINE IN TOPICAL

FORMULATION BY SIA COUPLED WITH MONOLITHIC COLUMN P C73 Klinkhammer, W., Müller, H., Sievers, J., Breitbach, K., Wiese, M. NEW TETRAHYDROISOQUINOLIN-DERIVATES AS MODULATORS OF P-

GLYCOPROTEIN P C74 Kohfeld, S., Schmitt, S., Meijer, L., Kunick, C. STRUCTURE-ACTIVITY RELATIONSHIPS FOR INHIBITION OF

MITOCHONDRIAL MALATE DEHYDROGENASE BY PAULLONES P C75 Kolp, S., Gütschow, M. INFLUENCE OF COMPATIBLE SOLUTES ON ENTEROPEPTIDASE-

CATALYZED PROCESSING OF TRYPSINOGEN P C76 Konter, J., Abuo-Rahma, G., Lehmann, J. KINETIC STUDIES AND AN IMPROVED SYTHESIS OF DIAZEN-1-IUM-1,2-

DIOLATES (“SOLID NO”) USING THE NOTIZER© P C77 Kopec, S., Holzgrabe, U. METHODS TO EVALUATE THE IMPURITY PROFILE OF AMINO ACIDS BY

MEANS OF CAPILLARY ELECTROPHORESIS P C78 Kubas, H., Mach, U., Wermuth, C. G., Schwartz, J.-C., Sokoloff, P., Stark, H. NEW LEADS FOR DOPAMINE D2/3 RECEPTOR LIGANDS:

ALKYLPIPERIDINO ANALOGUES OF BP 897

33

Poster Contributions P C79 Kuča, K., Cabal, J., Ševelová-Bartošová, L., Krejčová-Kunešová, G., Jun, D. IN VITRO REACTIVATION OF ACETYLCHOLINESTERASE INHIBITED BY

CYCLOSARIN P C80 Kučera, R., Sochor, J., Klimeš, J. NEW APPROACH TO QUALITY CONTROL OF IBUPROFEN USING

DISCOVERY ZIRCONIA COLUMN P C81 Kunze, M., Geyer, G., Elz, S. 2-ALKYL- AND 2-PHENYLIMIDAZOLYLPROPANOXY-ACETOPHE-NONES –

POTENTIAL HISTAMINE H1-/H3-RECEPTOR LIGANDS P C82 Lange, S., Bracher, F. NOVEL AZASECO–STEROID BASED ANTIMICROBIAL AGENTS P C83 Latussek, E., Hanefeld, W. SYNTHETIC POTENTIAL OF CYCLIC IMINIUM- AND HYDRAZINIUM-

DITHIOCARBONIC ACID DERIVATIVES P C84 Łażewska, D., Kieć-Kononowicz, K., Elz, S., Stark, H., Schunack, W. LIPOPHILICITY OF ALIPHATIC CARBAMATES - HISTAMINE H3 RECEPTOR

ANTAGONISTS P C85 Liedtke, A., Domeyer, D., Laufer, S., DESIGN, SYNTHESIS & TESTING OF p38 MAP KINASE INHIBITORS –

INTERACTIONS WITH THE ENZYME’S HYDROPHOBIC REGION II – P C86 Lišková, A., Blešová, M. POTENTIOMETRIC PKa DETERMINATION OF WATER-INSOLUBLE

COMPOUNDS WITH POTENTIAL BIOLOGICAL ACTIVITY P C87 Lübbe, A. N.., Rickerts, B., Duchstein, H.-J., CHARACTERIZATION OF IMMOBILIZED METALLOPORPHYRINS P C88 Matysová, L., Solich, P., Marek, P., Šícha, J. DETERMINATION OF TERBINAFINE AND ITS DEGRADATION PRODUCTS IN

TOPICAL CREAM BY RP-HPLC. P C89 Maurer, A., Kraatz, H.-B., Metzler-Nolte, N. NEW DNA-BIOSENSORS WITH DIRECT ELECTROCHEMICAL DETECTION

BASED ON METAL-PNA-CONJUGATES P C90 Meis, S., Ullmann, H., Nickel, P., Communi, D., Boeynaems, J.-M.,

Kassack, M. U. THE SURAMIN ANALOGUE NF157 IS THE FIRST SELECTIVE AND POTENT

P2Y11 RECEPTOR ANTAGONIST P C91 oral Meindl, N., Steinhilber, D. IDENTIFICATION AND REGULATION OF THE RORa4 PROMOTER P C92 Meusel, M., Gütschow, M. NOVEL SYNTHESES OF N-ACYLUREAS: FROM SOLUTION TO SOLID-

PHASE CHEMISTRY

34

Poster Contributions P C93 Mikouchina, K., Laufer, S. MULTICONFORMER RECEPTOR- BASED QSAR STUDIE FOR p38 MAP

KINASE INHIBITORS P C94 Möllenbeck, J., Paitel, E., Westaway, D., Lemcke, T., Kunick, C. 7-AMINO-3,4-DIHYDRO-1H-1-BENZAZEPINE-2,5-DIONE, A POTENTIAL

INHIBITOR OF GAMMA-SECRETASE P C95 Mokrý, P., Kotlíková, S., Csöllei, J. DERIVATIVES OF ARYLCARBONYLOXYAMINOPROPANOLS, A NOVEL

POTENTIAL ULTRASHORT-ACTING b-BLOCKERS P C96 Müller, C., Bernhardt, G., Immisch, C., Weidensdorfer, D., Böhm, G.,

Buschauer, A. QUANTIFICATION OF SIRNA EFFECTS IN VITRO AND IN VIVO P C97 Muselík, J., García-Alonso, M., Martín-López, M. P., Žemlièka, M., Rivas-

Gonzalo, J. C. ANTIOXIDANT ACTIVITY OF WINE POLYPHENOLS MEASURED BY

DIFFERENT METHODS P C98 Ohnesorge, J., Sänger-van de Griend, C., Wätzig, H. LONG TERM PRECISION IN CAPILLARY-ELECTROPHORESIS

ELECTROSPRAY MASS-SPECTROMETRY P C99 Opatřilová, R., Kurfürst, P. A NEW SERIES OF BETAADRENERGIC RECEPTORS ANTAGONISTS P C100 Opletal, L., Jun, D., Opletalová, V., Chlupáčová, M., Hronek, M., Kuča, K. PLATELET ANTIAGGREGATING ACTIVITY OF SUBSTITUTED (E)-3-(3-

HYDROXYPHENYL)-1-PYRAZIN-2-YLPROP-2-EN-1-ONES P C101 Opletalová, V., Chlupáčová, M., Posledníková, M., Kuneš, J., Silva, L.,

Buchta, V., Jun, D. SYNTHESIS AND BIOLOGICAL EVALUATION OF SUBSTITUTED (E)-1-(5- ISOPROPYLPYRAZIN-2-YL)-3-PHENYLPROP-2-EN-1-ONES P C102 Ortmann, R., Wiesner, J., Heidler, P., Thimann, W., Silber, K., Eisenmann, M.,

Jomaa, H., Link, A., Klebe, G., Schlitzer, M. STUDIES TOWARDS NOVEL ANTIMALARIAL AGENTS: DXR-INHIBITORS

WITH INCREASED LIPOPHILICITY P C103 Palek, L., Doležal, M., Buchta, V., Cermak, P. SYNTHESIS AND ANTIINFECTIVE EVALUATION OF PYRAZINAMIDE

ANALOGUES P C104 oral Ott, I., Gust, R. A COBALT-ALKYNE COMPLEX OF ASPIRIN AS CYTOTOXIC COX-INHIBITOR P C105 Paraschiv, G.-I., Striegl, B., Braun, C., Sunel, V., Cecal, A., Kunze, M., Elz, S. (±)-a-METHYL-2-(3-METHOXYPHENYL)HISTAMINE: THE FIRST CHIRAL

HISTAMINE ANALOGUE DISPLAYING SUFFICIENT H1-RECEPTOR AGONIST POTENCY

35

Poster Contributions P C106 Patil, R., Elz, S., Buschauer, A., Reiser, O. SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF SIDE-CHAIN

FUNCTIONALIZED HISTAPRODIFEN ANALOGUES P C107 Peifer, C., Luik, S., Thuma, S., Herweh, Y., Laufer, S. DEVELOPMENT AND OPTIMIZATION OF A NON-RADIOACTIVE JNK3 ASSAY P C108 Perruchon, J., Ortmann, R., Wiesner, J., Silber, K., Jomaa, H., Klebe, G.,

Schlitzer, M. STRUCTURE-BASED DRUG DESIGN OF NEW DXR-INHIBITORS P C109 Petrache, G., Xie, S.-X., Seifert, R., Schneider, E., Elz, S., Bernhardt, G.,

Buschauer, A. FLUORESCENT HISTAMINE H2 RECEPTOR ANTAGONISTS: SYNTHESIS

AND PHARMACOLOGICAL STUDIES ON H2R-Gsα FUSION PROTEINS P C110 Petriška, I., Polášek, M. SEPARATION AND DETERMINATION OF TERPENE ALCOHOLS BY

MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY P C111 oral Pietsch, M., Gütschow, M. NEW THIENO-1,3-OXAZIN-4-ONES AS INHIBITORS OF ACETYLCHOLIN-

ESTERASE AND LEUKOCYTE ELASTASE P C112 Pötschger, I., Presser, A. A CONVENIENT PREPARATION OF PIVALOBROMGLUCOSE, AN IMPROVED

GLYCOSYL DONOR IN THE KOENIGS-KNORR GLYCOSIDATION P C113 Posselt, D., Bethke, A., Gust, R. DNA CLEAVAGE AND CYTOTOXICITY BY NOVEL IRON SALEN COMPLEXES P C114 Preuß, H., Xie, S.-X., Seifert, R., Buschauer, A., Dove, S., HISTAMINE H2 AGONISTIC GUANIDINES: STRUCTURAL BASIS FOR

SPECIES SELECTIVE LIGAND-RECEPTOR INTERACTIONS P C115 Projahn, H., Holzgrabe, U. 2,4-DIARYL-1,5-DIHYDROXYMETHYL-3,7-DIAZABICYCLO[3.3.1] NONAN-9-

OLS: A NEW CLASS OF KAPPA OPIOID LIGANDS P C116 Prühs, C., Kunick, C. SYNTHESIS OF DARPONES WITH AMINOALKYL SIDE CHAINS P C117 oral Psurek, A., Scriba, G. K. E. APPLICATION OF NONAQUEOUS CAPILLARY ELECTROPHORESIS TO THE

SEPARATION OF PEPTIDES P C118 Rack, C., Matusch, R. EVALUATION OF DIFFERENT STRATEGIES FOR THE REMOVAL OF

TANNINS IN THE SCREENING FOR LEAD STRUCTURES P C119 oral Raunegger, K., Hödl, C., Strauss, W. S. L., Sailer, R., Kunert, O., Seger, C.,

Steiner, R., Haslinger, E., Schramm, H. W. SYNTHESIS AND BIOLOGICAL STUDIES OF A NEW HIGH-AFFINITY

FLUORESCENT LIGAND FOR THE PROGESTERONE RECEPTOR

36

Poster Contributions P C120 Rakowitz, D., Niedermoser, S., Pichler, W., Matuszczak, B. SYNTHESIS AND BIOLOGICAL EVALUATION OF A NOVEL CLASS OF

ALDOSE REDUCTASE INHIBITORS P C121 Renard, D., Bracher, F. SIDE CHAIN AZASTEROIDS AS POTENTIAL ERGOSTEROL BIOSYNTHESIS

INHIBITORS P C122 Rickerts, B., Duchstein, H.-J. RELEASE OF NITRIC OXIDE FROM COMPOUNDS SIMILAR TO Nw-

HYDROXY-L-ARGININE, AN INTERMEDIATE OF THE NO-BIOSYNTHESIS P C123 oral Reszka, P., Bednarski, P. J. A NEW, SENSITIVE RP-HPLC-ASSAY FOR SIMULTANEOUS DETECTION OF

CASPASE-3 AND -9 IN APOPTOTIC CANCER CELLS P C124 Ritter, A., Bracher, F., Pohl, B. BAUERINE C, DERIVATIVES UND SECO-DERIVATIVES AS NOVEL

INHIBITORS OF CYCLIN-DEPENDENT KINASES P C125 Ruff, K., Zimmermann, W., Laufer, S. TETRASUBSTITUTED IMIDAZOLES AS p38-MAP KINASE INHIBITORS:

OPTIMIZATION OF THE N-1 POSITION P C126 Sax, M., Berning, S., Wünsch, B. SPOS OF 2-SUBSTITUTED 2,3-DIHYDROPYRIDINE-4(1H)-ONES BY

HETERO-DIELS-ALDER-REACTION P C127 Šmejkal, K., Forejtníková, H., Vančo, J., Marek, R., Suchý, V. BIOLOGICAL ACTIVE C-GERANYL FLAVONOIDS FROM FRUITS OF

PAULOWNIA TOMENTOSA (SCROPHULARIACEAE) P C128 Syrovatko, M., Laznickova, A. SOLID PHASE EXTRACTION OF RADIOLABELLED QUINLUKAST FROM RAT

PLASMA P C129 Scheiber, J., Stiefl, N., Baumann, K. INCORPORATING CONFORMATIONAL FLEXIBILITY INTO QSAR –

VALIDATION OF A NOVEL 4D-QSAR TECHNIQUE P C130 Schirmeister, T., Vicik, R., Helten, H., Engels, B. THEORETICAL STUDIES ABOUT CYSTEINE PROTEASE INHIBITORS - HOW

VALID ARE PREDICTIONS? P C131 oral Scherer, C., Hartmann, R. W. STUDIES ON CACO-2 PERMEABILITY OF RESEARCH COMPOUNDS USING

LC/MS/MS P C132 Schlenk, M., von Rauch, M., Gust, R. STRUCTURE ACTIVITY RELATIONSHIP OF TYPE-II-ESTROGENS:

ESTROGENIC ACTIVITY OF 4,5-BIS(2-CHLORO-4-HYDROXYPHENYL)-2-IMIDAZOLINES

P C133 Schlotter, K., Hübner, H., Gmeiner, P. ANALOGS OF THE HIGHLY SELECTIVE DOPAMINE D3 RECEPTOR LIGAND

FAUC 346 WITH PLANAR CHIRALITY

37

Poster Contributions P C134 oral Schlimme, S., Jung, M., Sippl, W. MOLECULAR DYNAMICS SIMULATIONS OF THE HUMAN HISTONE

DEACETYLASE 1 (HDAC1) P C135 Schmidt, C., Krauss, J. STUDIES TOWARDS TOTAL SYNTHESIS OF AMPHIDINOLIDES T P C136 Steffen, A., Kämper, A., Lengauer, T. FLEXR – PREDICTING THE STRUCTURE OF HOST-GUEST COMPLEXES P C137 oral Schumacher, G., Fritzsche, J., Hünerbein, I., Ludwig, R., Zeisig, R.,

Bendas, G. INVOLVEMENT OF P-SELECTIN IN THE ADHESION MECHANISM OF

TUMOUR CELLS TO THE ENDOTHELIUM IN METASTASIS P C138 Stiefl, N., Baumann, K. MAP - STRUCTURE-BASED VALIDATION OF A 3D-QSAR TECHNIQUE P C139 oral Steger, S., Höller, K., Rieder, M., Vigl, F., Hinz, S., Schumacher, B., Müller, C.

E., Matuszczak, B. NOVEL PYRAZOLYL-SUBSTITUTED [1,2,4]-TRI-AZOLO-[4,3-a]-QUINOX-

ALINES AS ADENOSINE RECEPTOR ANTAGONISTS P C140 Straßer, A. A MODULE FOR APPROXIMATE CALCULATION OF A LIGANDS PATHWAY

INTO A RECEPTOR P C141 Streiber, M., Picard, F., Scherer, C., Seidel, S. B., Hartmann, R. W. NEW STRATEGY FOR DUAL INHIBITION OF 5a-REDUCTASE TYPE 1 AND

TYPE 2 FOR THE TREATMENT OF BPH P C142 Striegl, B., Kunze, M., Elz, S. A NEW METHOD FOR SYNTHESIZING Na-HETEROCYCLYLALKYL

DERIVATIVES OF HISTAPRODIFEN P C143 Thuma, S., Greim, C., Herweh, Y., Laufer, S. A NON-RADIOACTIVE, IN VITRO p38a MAP KINASE ASSAY THAT FITS

REQUIREMENTS OF HIGH-THROUGHPUT SCREENING P C144 Tretiakova, I., Michel, A., Ulke, A., Steinhilber, D., Werz, O. CASPASE-6 REGULATES METABOLISM OF 5-LIPOXYGENASE PROTEIN IN

PROLIFERATING B-LYMPHOCYTIC CELLS P C145 Ulbrich, C., Ludwig, R., Boehncke, W.-H., Bendas, G. TARGETING OF SELECTIN-DIRECTED IMMUNOLIPOSOMES TO INDUCE A

SITE-SPECIFIC DRUG RELEASE P C146 Unger, M., Laug, S., Holzgrabe, U. CAPILLARY ZONE ELECTROPHORESIS AS A TOOL FOR THE QUALITY

CONTROL OF GOLDENSEAL EXTRACTS P C147 Ungvári, J., Dobner, B., Langner, A., Schmidt, M. ALKYLATION OF DIBENZOANELLATED CYCLIC KETONES FOR SYNTHESIS

OF POTENTIAL MDR-MODULATORS

38

Poster Contributions P C148 Unterreitmeier, D., Krauss, J. NEW APPROACH TOWARDS IPOMEANOL AND RELATED COMPOUNDS P C149 Vicik, R., Stiefl, N., Baumann, K., Schirmeister, T. PROLINE CONTAINING INHIBITORS OF CATHEPSINS AND CATHEPSIN-

LIKE PARASITIC PROTEASES P C150 Waibel, B., Scheiber, J., Kahle, C., Holzgrabe, U. ANALYSIS OF β-CYCLODEXTRIN INCLUSION COMPLEXES WITH

DIPEPTIDES IN PRESENCE OF UREA BY NMR-SPECTROSCOPY P C151 Wendelin, W., Hojas, S., Gößnitzer, E. A NEW ROUTE TO 3-(2-AMINOETHYL)-2,2-DIMETHYL-3-CYCLOHEXENONE

AS A SYNTHON FOR 8,13,15-TRIAZASTEROL-RELATED ANTIMYCOTIC AGENTS

P C152 Wirt, U., Wünsch, B. NMDA-ANTAGONISTS: ASYMMETRIC SYNTH SIS1OF B-SUTSTIDUTE3

2,5,4,T-TEYRAH-DRO31H-N-BEEZAZEPINES P C153 oral Wolf, M., Bauder-Wüst, U., Mohammed, A., Schönsiegel, F., Mier, W.,

Haberkorn, U., Eisenhut,M. ALKYLATING BENZAMIDES WITH MELANOMA CYTOTOXICITY P C154 Zuse, A., Prinz, H., Müller, K., Böhm, K., Stoiber, T., Günther, E., Unger, E., SYNTHESIS, GROWTH INHIBITORY ACTIVITY AND INHIBITION OF TUBULIN

POLYMERIZATION BY NOVEL 9-BENZYLIDENE-NAPHTHO[2,3-b]THIO-PHENE-4-ONE PHOSPHATES

P C155 oral Zlotos, D. P., Buller, S., Gündisch, D., Mohr, K. BISQUATERNARY DIMERS OF STRYCHNINE AS POTENT ENHANCERS OF

LIGAND BINDING TO M2 RECEPTORS History of Pharmacy P G1 Bernschneider-Reif, S., Staiger, C. 80 JAHRE KOHLE-COMPRETTEN VON MERCK – PERFEKTIONIERUNG

EINER TRADITIONSREICHEN THERAPIE P G2 Bernschneider-Reif, S. DIE MARKE MERCK IM WANDEL DER ZEIT P G3 Mannetstätter, A. "VITRIOLO" - DER APOTHEKER IN HUGO WOLFS OPERNFRAGMENT

"MANUEL VENEGAS" P G4 Staiger, C., Bernschneider-Reif, S. MARKENSTAMMBÄUME ALS WISSENSCHAFTSHISTORISCHE QUELLE

39

Poster Contributions Clinical Pharmacy P K1 oral Frank, A., Unger, M. VALIDATION OF AN IN VITRO METHOD FOR THE SCREENING OF PLANT

EXTRACTS INTERACTING WITH CYT P450 ENZYMES P K2 Garmann, D., Warnecke, A., Kratz, F., Jaehde, U. REACTIVITY OF NOVEL ALBUMIN BINDING PLATINUM COMPLEXES P K3 oral Haen, E., Goepfert, C. RELEVANCE OF CLINICAL PHARMACOLOGICAL COMMENTS IN TDM P K4 Goepfert, C., Ostermeier, C. P., Haen, E. VALPROATE-INDUCED ENCEPHALOPATHY: A DEPICT-ION OF SYMPTOMS

ON THE BASIS OF A CASE REPORT P K5 oral Hoppe, N., Kunze, T., Gieseler, F., Glasmacher, A., Borleri, G., Bassan, R.,

Barbui, T. IN VIVO PHARMACOKINETICS OF IDARUBICIN P K6 Kibbel, T., Süfke, S., Dodt, C., Djonlagic, H. EXTENDED ECG ANALYSIS IN ADDITION TO SERUM LEVEL EVALUATIONS

IN INTOXICATIONS WITH TRICYCLIC ANTIDEPRESSANTS P K7 oral Lehr, T., Krug-Schmid, R., Tillmann, C., Staab, A., Trommeshauser, D.,

Schaefer, H. G., Kloft, C. POPULATION PHARMACOKINETIC MODEL OF A CNS ACTIVE DRUG AND

ITS METABOLITE P K8 Macešková, B., Blechová, R., Ondrášiková, H. PRESCRIPTION OF HYPNOTICS IN OUT-PATIENTS IN THE CZECH

REPUBLIC P K10 Plock, N., Kloft, C. PH-DEPENDENCY OF MICRODIALYSIS RECOVERY – IN VITRO

MICRODIALYSIS OF VANCOMYCIN P K11 Fischer, W. H., Gschaidmeier, H., Färber, L. CLINICAL EFFICAY AND SAFETY OF ENTERIC-COATED MYCOPHENOLATE

SODIUM IN DE NOVO AND MAINTENANCE KIDNEY TRANSPLANT RECIPIENTS

P K12 Priller, S., Unger, M., Holzgrabe, U. HPLC DETERMINATION OF THE PARAXANTHINE/CAFFEINE RATIO IN

SALIVA FOR PHENOTYPING CYTOCHROME P450 1A2 P K13 oral Schaad, S., Vokata, V., Garmann, D., Scheuch, E., Henke, M., Hauses, M.,

Hilger, R. A., Scheulen, M. E., Dittrich, C., Keppler, B. K., Jaehde, U. PHARMACOKINETICS OF A NOVEL RUTHENIUM (III) COMPLEX IN

PATIENTS WITH SOLID TUMOURS P K14 Scheller, C., Krauss, M., Färber, L., Gschaidmeier, H. FTY720: A NOVEL IMMUNOSUPPRESSIVE AGENT THAT INHIBITS

LYMPHOCYTE MIGRATION

40

Poster Contributions P K15 Uhl, J., Schlich, C., Springer, D., Grezniok, A., Schlesinger, H.,

Rothenhaeusler, K., Le, V. H. DEVELOPMENT OF RIBAVIRIN CAPSULES: 94 PERCENT COST SAVINGS

AND ZERO PERCENT LOSS OF QUALITY P K16 Westfeld, M., Langenbahn, D., Eckhardt, M., Liekweg, A., Erdfelder, E.,

Jaehde, U. RELATIONSHIP BETWEEN PATIENT SATISFACTION WITH INFORMATION

AND QUALITY OF LIFE IN CANCER PATIENTS P K18 Mazánková, D., Kolar, J., Kotolová, H., Bartošíková, L. EXPERIENCE WITH UNIT DOSE SYSTEM OF DRUG DISTRIBUTION IN

CZECH REPUBLIC Pharmacology / Toxicology P P1 Bader, W., Melchner, D., Nonenmacher, T., Haen, E. DETERMINATION OF FIVE ANTIPSYCHOTICS IN HUMAN SERUM BY HPLC

AND ELECTROCHEMICAL DETECTION P P2 oral Bartošíková, L., Nečas, J., Suchý, V., Kubínová, R., Lišková, M., Florian, T.,

Kollar, P., Kotolová, H., Mazánková, D., Bartosik, T., Klusakova, J., Janostikova, E., Göpfert, E., Bartosova, L., Strnadova, V.

ANTIOXIDATIVE EFFECT OF POMIFERINE IN ISCHEMIA-REPERFUSION OF LABORATORY RAT KIDNEY TISSUE (EFFECT IN PROPHYLAXIS)

P P3 Bartošová, L., Novak, F., Parak, T., Frydrych, M., Bebarova, M., Brunclik, V.,

Kolevska, J., Mokrý, P., Opatřilová, R., Florian, T., Nečas, J., Bartošíková, L. ANTIARRHYTHMIC EFFECT OF COMPOUND 44BU – NEWLY SYNTHESIZED

ULTRASHORT ACTING BETA-ADRENOLYTICS P P4 oral Bernsdorf, A. INFLUENCE OF TALINOLOL ON SIMVASTATIN PHARMACOKINETICS AS

ASSESSED BY A SENSITIVE LC-MS/MS ASSAY P P5 oral Bur, M., Ehrhardt, C., Kim, K. J., Lehr, C. M. BIOELECTRIC PROPERTIES OF PRIMARY CULTURED TIGHT

MONOLAYERS OF HUMAN ALVEOLAR EPITHELIAL CELLS (HAEPC) P P6 Eichele, K., Ramer, R., Hinz, B. CANNABINOID-INDUCED CYCLOOXYGENASE-2 EXPRESSION IN HUMAN

NEUROGLIOMA CELLS: POSSIBLE INVOLVEMENT OF LIPID RAFTS P P7 Florian, T., Kurfürst, P., Nečas, J., Bartošíková, L., Frydrych, M., Janostikova, E.,

Parak, T., Kotolová, H., Bartošová, L. CARDIOPROTECTIVE EFFECT OF NEWLY SYNTHESIZED DERIVATIVES OF HETEROARYLAMINOETHANOLES UNDER CONDITION OF HEART INJURY P P8 oral Forejtníková, H., Zítková, H., Kubínová, R., Machala, M. CHEMOPROTECTIVE AND TOXIC POTENTIALS OF COUMARINS IN VITRO P P9 Frydrych, M., Bartošová, L., Florian, T., Nečas, J., Bartošíková, L., Krčmář, J.,

Mokrý, P. THE NEW ULTRA-SHORT ACTING BETA BLOCKER INFLUENCES SYSTOLIC

BLOOD PRESSURE IN RATS

41

Poster Contributions P P10 Germann, I., Kelber, O., Vinson, B., Weiser, D., Heinle, H. THE EFFECT OF STW 5 IN IN VITRO-MODELS IS BASED ON ADDITIVE AND

SUPRAADDITIVE EFFECTS OF ITS COMPONENTS P P11 Greiner, C. , Melchner, D. , Hiemke, C. , Haen, E. DETECTION OF CITALOPRAM AND ITS MAIN METABOLITE

DESMETHYLCITALOPRAM BY COLUMN-SWITCHING HPLC P P12 Hohenester, B., Rühl, A., Kelber, O., Weiser, D., Schemann, M. REGION-SPECIFIC EFFECTS OF THE FIXED HERBAL COMBINATION STW 5

AND ITS COMPONENTS ON GASTRIC MOTILITY P P13 oral Huether, A., Höpfner, M., Sutter, A. P., Brunk, I., Ahnert-Hilger, G., Scherübl, H. UNLABELLED META-IODOBENZYLGUANIDINE IN THE TREATMENT OF

GASTROINTESTINAL NEUROENDOCRINE TUMORS P P14 oral Janostikova, E., Bartošíková, L., Nečas, J., Bartosik, T., Florian, T., Frydrych, M.,

Klusakova, J., Göpfert, E. ANTIOXIDATIVE EFFECT OF QUERCETINE IN ISCHEMIA-REPERFUSION OF

LABORATORY RAT KIDNEY TISSUE (EFFECT IN THERAPY) P P15 Kollár, P., Kotolová, H., Karpíšek, M., Bartošíková, L., Pechmann, V., Nečas, J. PURIFICATION OF LEPTIN RECEPTOR FROM HUMAN SERUM P P16 Kotolová, H., Kollár, P., Karpíšek, M., Mazánková, D., Bartošíková, L., Florian, T.,

Cerháková, K., Nečas, J. QUANTITATIVE MEASUREMENT OF LEPTIN RECEPTOR P P17 Kühn, S., Klöcking, H.-P., Klöcking, R. INVESTIGATIONS ON THE UV-B PROTECTIVE EFFECT OF HUMIC ACIDS,

HUMIC ACID-LIKE POLYMERS AND PABA P P18 Moritz, A., Gust, R., Glusa, E., Pertz, H. H. RALOXIFENE INDUCES RELAXATION IN PIG CORONARY ARTERIES VIA

BLOCKADE OF L-TYPE CALCIUM CHANNELS P P19 oral Nečas, J., Bartošíková, L., Suchý, V., Kubínová, R., Lišková, M., Bartosik, T.,

Janostikova, E., Florian, T., Frydrych, M., Krcmar, J., ANTIOXIDATIVE EFFECT OF POMIFERINE IN ISCHEMIA-REPERFUSION OF

LABORATORY RAT KIDNEY TISSUE (EFFECT IN THERAPY) P P20 oral Oswald, S., Haenisch, S., Giessmann, T., Schroeder, E., Warzok, W.,

Cascorbi, I., Siegmund, W. PHARMACOKINETIC INTERACTIONS BETWEEN EZETIMIBE AND THE PXR-

INDUCER RIFAMPICIN IN HEALTHY VOLUNTEERS P P21 Prilla, S., Muth, M., Holzgrabe, U., Ellis, J., Mohr, K. EPITOPES OF THE MUSCARINIC M2 RECEPTOR FOR THE ALLOSTERIC

ENHANCER NAPHMETHONIUM P P22 Reischl, G., Hummerich, R., Ehrlichmann, W., Solbach, C., Schloss, P.,

Machulla, H.-J. DASB – A LIGAND FOR THE SEROTONIN TRANSPORTER – AN IN VITRO

STUDY

42

Poster Contributions P P23 oral Schempp, H., Hippeli, S., Kelber, O., Weiser, D., Elstner, E. F. ANTI-OXIDANT / ANTI-INFLAMMATORY EFFECT OF STW 5 AND ITS

COMPONENTS P P24 Sennwitz, M., Muth, M., Scharfenstein, O., Holzgrabe, U., Mohr, K. SUBTYPE-SELECTIVITY OF BIS(AMMONIO)ALKANE-TYPE MUSCARINIC

ALLOSTERIC MODULATORS P P25 Stecova, J., Sivaramakrishnan, R., Mehnert, W., Kramer, K. D., Zouboulis, C. C.,

Schäfer-Korting, M. INNOVATIVE DRUG CARRIERS FOR TOPICAL CYPROTERONE ACETATE

THERAPY OF ANDROGENETIC ALOPECIA AND ACNE P P26 Storr, M., Weiser, D., Kelber, O., Schirra, J., Allescher, H. D., Sibaev, A. PHYTOPHARMACA LIKE STW5 CAUSE CHANGES OF SMALL INTESTINAL ELECTROPHYSIOLOGICAL PROPERTIES. P P27 Strassmann, V., Mohr, K. DEPENDANCE ON RECEPTOR EPITOPES OF A MUSCARINIC ALLOSTERIC

AGENT UNDER DIFFERENT BUFFER CONDITIONS P P28 oral Sutter, A. P., Maaser, K., Grabowski, P., Hüther, A., Bradacs, G., Vormbrock, K.,

Höpfner, M., Krahn, A., Heine, B., Stein, H., Somasundaram, R., Schuppan, D., Zeitz, M., Scherübl, H.

PERIPHERAL BENZODIAZEPINE RECEPTOR LIGANDS ENHANCE CHEMOSENSITIVITY OF HEPATOCELLULAR CARCINOMA CELLS

P P29 oral Verspohl, E. J., Nahrstedt, A., Ploch, M., Windeck, T., Abel-Aziz, H. IN VITRO STUDIES TO ELUCIDATE THE MODE OF ACTION OF THE ACTIVE

PRINCIPLES OF GINGER (ZINGIBER OFFICINALE) P P30 Taetz, S., Baldes, C., Schaefer, U. F., Lehr, C. M. INHIBITION OF TELOMERASE ACTIVITY IN HUMAN LUNG CANCER CELLS

BY BRACO19 P P31 oral Vytlačilová, J., Chobot, V., Jahodář, L., Kubicová, L. PHOTOTOXIC PROPERTIES OF SOME HALOGENATED SALICYLANILIDES P P32 Weiland, F., Verspohl, E. J. ANGIOTENSIN II RECEPTORS IN PREADIPOSE CELLS AND MATURE

ADIPOCYTES AS PART OF A PARACRINE RAA SYSTEM P P33 Ziemek, R., Bernhardt, G., Cabrele, C., Beck-Sickinger, A., Buschauer, A. THE FLUORESCENT LIGAND CY5-[K4]HPP: A NEW TOOL FOR BINDING

ASSAYS OF NPY Y4 RECEPTOR LIGANDS P P34 Schweinsberg, C., Ebenhan, T., Ehrlichmann, W., Kuntzsch, M., Solbach, C.,

Machulla, H.-J. IN VITRO EVALUATION OF CHOLINE AND FLUORO ANALOGUES OF

CHOLINE FOR IMAGING PROSTATE CANCER WITH PET

43

Poster Contributions Pharmaceutical Technology P T1 Albers, J., Knop, K., Kleinebudde, P. BRAND-TO-BRAND AND BATCH-TO-BATCH UNIFORMITY OF

MICROCRYSTALLINE CELLULOSE P T2 Aurich, K., Brinkmeier, V., Glöckl, G., Nagel, S., Weitschies, W. INVESTIGATIONS OF BINDING KINETICS BY MAGNETO-OPTICAL

RELAXATION MEASUREMENTS P T3 Beilmann, B., Langguth, P., Graß, P., Häusler, H. INFLUENCE OF CAPSULE MATERIAL ON THE AEROSOLIZATION

CHARACTERISTICS OF DRY POWDER INHALATION PRODUCTS P T4 Bertocchi, P., Antoniella, E., Valvo, L., Alimonti, S., Memoli, A. DICLOFENAC SODIUM MULTISOURCE PROLONGED RELEASE TABLETS –

A COMPARATIVE STUDY ON THE DISSOLUTION PROFILES P T5 Blümer, C., Mäder, K. THE INFLUENCE OF ISOSTATIC ULTRA HIGH PRESSURE ON

SUPERCOOLED MELTS IN COLLOIDAL LIPID DISPERSIONS P T6 Borowski, M., Steckel, H. INFLUENCE OF WATER ON THE PHYSICAL STABILITY OF A NON-POLAR

SUSPENSION FORMULATION IN A PMDI P T7 Brudy, J. A., Bultmann, J. M. COMPARISON OF POWDER PYCNOMETRY (GEOPYC 1360) AND PUNCH

METHOD TO DETERMINE KNURLED RIBBON DENSITY P T8 oral Bultmann, J. M., Brudy, J. A. ROLL PRESS INSTRUMENTATION OF A MINIPACTORÔ P T9 Buech, G., Siebenbrodt, I., Borchert, H.-H. IMMUNOSUPPRESSIVE LIPOSOMAL DRUG FORMULATIONS FOR TOPICAL

TREATMENT OF CHRONIC INFLAMMATORY DERMATOSES P T10 Bunjes, H. SATURATED PHOSPHOLIPIDS PROMOTE CRYSTALLIZATION BUT SLOW

DOWN POLYMORPHISM IN LIPID NANOPARTICLES P T11 Collnot, E. M., Ehrhardt, C., Bies, C., Schaefer, U. F., Lehr, C. M. THE HUMAN BRONCHIAL EPITHELIAL CELL LINE CFBE41o- AS AN

IN VITRO MODEL FOR CYSTIC FIBROSIS STUDIES P T12 Farrenkopf, J., Bultmann, J. M. ROLL COMPACTION: THE EFFECT OF FINE AND COARSE PARTICLE

FRACTIONS ON GRANULE AND TABLET PROPERTIES P T13 Franc, A., Zaludek, B., Gonec, R. TECHNOLOGY FOR DOSAGE FORMS WITH HIGH LEVEL OF CONTENT

UNIFORMITY P T14 Frentzel, A., Cambon, N., Reher, M., Martin, W., Scheiwe, W. GALENICAL FORMULATION, MANUFACTURE AND TRANSDERMAL

PROPERTIES OF A NEWLY DEVELOPED DICLOFENAC-NA PATCH

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Poster Contributions P T15 Gentz, A., Gröning, R. DEVELOPMENT OF SUSTAINED RELEASE GASTRORETENTIVE DOSAGE

FORMS OF ACYCLOVIR P T16 oral Grueneberg, D., Breitkreutz, J., Pöstges, R., Gröning, R. ADVANCED ORAL REHYDRATION SALT (ORS) SOLUTIONS WITH

PLEASANT TASTE P T17 oral Gruetzmann, R., Wagner, K. G. PLASTICIZER LEACHING FROM EUDRAGIT RS 30D MEMBRANES - PROOF

OF AN IONIC INDUCED TRANSPORT MECHANISM? P T18 Gryczová, E., Rabišková, M. COMPARISON OF CELLETS® AND SUGAR SPHERES AS INERT CORES

FOR DRUG SOLUTION LAYERING P T19 Hoffmann, C., Müller-Goymann, C. C. USE OF ARTIFICIAL SKIN CONSTRUCTS IN PERMEATION STUDIES OF

CLINDAMYCIN PHOSPHATE P T20 Hussein, F., Daniels, R. DETERMINATION OF LYSOZYME ACTIVITY AFTER STORAGE IN PRIMARY

PACKAGING MATERIALS USING FLUORIMETRY P T21 Knerr, R., Steinem, C., Roberts, C. J., Göpferich, A. SELF-ASSEMBLED MONOLAYERS OF PEGYLATED ALKANETHIOLATES ON

GOLD – A MODEL SYSTEM TO INVESTIGATE CELL-SURFACE INTERACTIONS

P T22 Langguth, P., Ofer, M., Shirasaka, Y., Yamashita, S., Spahn-Langguth, H. INHIBITION OF OCT-MEDIATED TRANSPORT BY CARVEDILOL AND ITS

MAJOR METABOLITES P T23 oral Leopold, C. S., Andrä, W., Danan, H., Dutz, S., Knauft, S., Werner, C.,

Bellemann, M. E., SITE-SPECIFIC DRUG DELIVERY TO THE GASTROINTESTINAL TRACT: A

NOVEL APPROACH P T24 Lohrmann, M., Grimsey, I. M., Urbanetz, N. A., Lippold, B. C. DO FINE PARTICLE FRACTION AND SURFACE ENERGY OF CARRIERS FOR

DRY POWDER INHALERS CORRELATE? P T25 Lungwitz, U., Breunig, M., Blunk, T., Göpferich, A. SYNTHESIS AND APPLICATION OF LOW MOL. WEIGHT LINEAR

POLYETHYLENIMINES FOR NON-VIRAL TRANSFECTION P T26 Markefka, P., Steckel, H., teWierik, H., Kammelar, R. LACTOSE PRE-TREATMENT AS A MEANS TO INFLUENCE DELIVERY

PERFORMANCE FROM DPIS P T27 Maurath, S., Daniels, R. INLUENCE OF PROCESSING AND POLYMER QUANTITY ON THE STABILITY

OF ETHYLCELLULOSE-STABILIZED W/O-EMULSIONS

45

Poster Contributions P T28 Medvecká, G., Rabišková, M. MATRIX TABLETS WITH LIPOPHILIC CARRIER AND

HYDROXYPROPYLMETHYLCELLULOSE P T29 Meyer, L., Reichl, S. ESTERASE ACTIVITY OF HUMAN ORGANOTYPIC CORNEA CONSTRUCT P T30 Möschwitzer, J. , Müller, R. H. A NOVEL IN VITRO DETERMINATION METHOD TO EVALUATE THE

MUCOADHESION PROPERTIES OF NANOPARTICLES P T31 Müller, R. S. DEVELOPMENT OF MOLECULAR CARRIERS: MODELING INVESTIGATIONS

INTO PVP – CYTOSTATIC INTERACTIONS P T32 Netzlaff, F., Meiers, P., Lehr, C. M., Wertz, P., Schaefer, U. INFLUENCE OF PROLONGED CRYOCONSERVATION ON HUMAN SKIN

LIPIDS P T33 Nykamp, G., Bechthold, I., Rafler, G., Girreser, U., Müller, B. W. BLOCKLENGTH DETERMINATION OF NON STATISTICAL POLY(LACTIDE-

CO-GLYCOLIDES) AND ITS INFLUENCE ON POLYMER PROPERTIES P T34 Ofer, M., Langguth, P., Zeller, W. J., Spahn-Langguth, H. THE USE OF PARENTAL AND MDR1-TRANSFECTED OVARIAN CARCINOMA

CELL LINES TO STUDY TRANSPORT MODULATION BY FLAVONOIDS P T35 oral Oliczewski, S., Daniels, R. A NOVEL FIBER-OPTIC PULSE LASER TOOL FOR IN-SITU STABILITY

ASSESSMENT OF DISPERSED SYSTEMS P T36 Omer-Adam, M.-A., Bednarski, P. J., Weitschies, W. STABILIZATION, SOLUBILIZATION AND I.V.-FORMULATION OF A DRUG

WITH POOR SOLUBILITY AND STABILITY IN WATER P T37 Pauli, A., Knop, K., Lippold, B. C. PELLET GROWTH VIA THE IMMERSION AND LAYERING MECHANISM: A

MATHEMATICAL APPROACH P T38 Pichert, L., Müller, B. W. EXTRACTION OF PHENOLIC DITERPENES FROM SAGE (SALVIA

OFFICINALIS) USING THE AEROSOL SOLVENT EXTRACTION SYSTEM (ASES)

P T39 Rabišková, M., Savickas, A., Ramanauskienė, K., Masteiková, R., Chalupová, Z. PREPARATION OF LIQUID EXTRACTS BY REPERCOLATION P T40 oral Rein, H. EXTRUDETTEN: SOLID DISPERSIONS AND SOLUTIONS BASED ON

STARCH P T41 oral Scheler, S. AN OPTIMIZED PREDICTION FOR THE NANOSTRUCTURE OF DRUG

CARRIERS MADE BY DISPERSION POLYMERIZATION

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Poster Contributions P T42 Rosenblatt, K., Douroumis, D., Bunjes, H. DRUG RELEASE STUDIES ON MONOOLEIN/ POLOXAMER DISPERSIONS

USING DIFFERENTIAL PULSE POLAROGRAPHY P T43 oral Schiller, C., Fröhlich, C. P., Gießman, T., Modeß, C., Siegmund, W., Hosten, N.,

Weitschies, W. MAGNETIC RESONANCE IMAGING TO ASSESS INTESTINAL FLUID

VOLUMES AND TRANSPORT OF INDIGESTIBLE MARKERS P T44 oral Scherliess, H., Nykamp, G., Müller, B. W. INVESTIGATIONS OF THE DEGRADATION PATTERN OF BLOCKED

POLY(LACTIDE-CO-GLYCOLIDES) IN COMPARISON WITH THEIR STATISTICAL ANALOGUES

P T45 Schöttle, I., Böck, G., Bender, H., Langguth, P. CHARACTERIZATION OF SPRAY-DRIED PLGA MICROPARTICLES LOADED

WITH BUDESONIDE P T46 oral Schlüter, B., Oppel, K., Meusel, M., Schröder, K., von Woedtke, T.,

Weitschies, W. ALTERATION OF CYTOCOMPATIBILITY AND PROPERTIES OF SURFACES

OF BIOMATERIALS BY STERILISATION PROCESSES P T47 Schurad, B., Tack, J., Lipp, R. TRANSDERMAL DELIVERY OF THE DOPAMINE AGONIST PROTERGURIDE

FROM DRUG IN ADHESIVE MATRIX SYSTEMS P T48 Schwier, S., Vogt, R., Müller, R. S., Gröning, R. MOLECULAR MODELING STUDIES ON POLOXAMER AND ITS

INTERACTIONS WITH DRUGS P T49 Timmermann, I.-L., Steckel, H. A STUDY ON THE RE-CRYSTALLIZATION BEHAVIOUR OF AMORPHOUS

LACTOSE USING THE RH-PERFUSION CELL P T50 Trommer, H., Neubert, R. H. H. SCREENING FOR NEW ANTIOXIDATIVE COMPOUNDS FOR TOPICAL

ADMINISTRATION USING LIPID MODEL SYSTEMS P T51 Valenta, C., Auner, B. G. PERMEATION OF 5-AMINOLEVULINIC ACID IN COMBINATION WITH A

LIPOPHILIC COUNTERION FROM A SEMISOLD PREPARATION P T52 oral Urbanetz, N. A. HOMOGENEITY OF INTERACTIVE MIXTURES OF SALBUTAMOL SULPHATE

AND α-LACTOSE-MONOHYDRATE OR MANNITOL P T53 van Venrooy, I., Müller, B. W., Laue, C., Schrezenmeir, J. VIABILITY OF ENCAPSULATED LACTOBACILLUS ACIDOPHILUS AFTER

DIFFERENT DRYING PROCESSES P T54 Viernstein, H., Köhler, G., Parasuk, W., Weiss-Greiler, P., Wolschann, P. INFLUENCE OF CYCLODEXTRIN COMPLEXATION ON THE PROTON

TRANSFER IN MANNICH BASES

47

Poster Contributions P T55 Vogel, T., Volk, B., Hacker, M., Göpferich, A., Schulz, M. B. COMPARATIVE STUDY OF IN-VITRO-CULTIVATION METHODS FOR TISSUE

ENGINEERING OF BONE P T56 Volk, B., Vogel, T., Rohde, E., Strunk, D., Göpferich, A., Schulz, M. B. FLOW CYTOMETRIC ANALYSIS OF PLASTIC-ADHERENT RAT BONE

MARROW CELLS P T57 Wedemeyer, R.-S., Rose, C., Weitschies, W. DETERMINATION OF FRONT MOVEMENTS AND IN SITU HYDROGEL

VISCOSITY DURING DRUG DISSOLUTION FROM HYDROPHILIC MATRIX TABLETS BASED ON HYDROXYPROPYL METHYL CELLULOSE

P T58 Weiss, B., Lamprecht, A., Stallmach, A., Schaefer, U. F., Lehr, C. M. NEW APPROACH FOR INVESTIGATING COLON TARGETING BY

FLUORESCENT NANOPARTICLES P T59 oral Weiss-Greiler, P., Viernstein, H., Hofer, E., Wolschann, P. INVESTIGATION ON THE SOLUBILITY BEHAVIOUR OF SPIRONOLACTONE

IN COMPLEXATION WITH CYCLODEXTRINS P T60 Wischke, C., Zimmermann, J., Lorenzen, D. R., Borchert, H.-H. ACTIVATION OF HUMAN DENDRITIC CELLS BY BIODEGRADABLE

MICROPARTICLES P T61 Eyrich, D., Milz, S., Wenzel, M., Staudenmaier, R., Göpferich, A., Blunk, T. CARTILAGE ENGINEERING USING A LONG-TERM STABLE FIBRIN GEL P T62 Weiser, B., Neubauer, M., Sommer, F., Göpferich, A., Blunk, T. ASCORBIC ACID ENHANCES ADIPOGENESIS OF RAT MARRIW STROMAL

CELLS

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