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PRE-FEASIBILITY REPORT FOR THE EXPANSION OF SPECIALTY FINE CHEMICALS, BULK DRUGS, COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s. Somu Organo-Chem Pvt. Ltd., #20, 29 th main, 1 st phase 2 nd stage B.T.M layout Bangalore-76 At Shed No.C-29, C-30 & adjacent plots KSSIDC Industrial Estate Malur-563 130 Kolar District Environmental Consultants AQUATECH ENVIRO ENGINEERS # 3391, 6 th Main, 3 rd Cross, RPC Layout Vijayanagar II Stage Bangalore – 560 040 Tele Phone : 080 23141679
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Page 1: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

PRE-FEASIBILITY REPORT FOR THE EXPANSION

OF

SPECIALTY FINE CHEMICALS, BULK DRUGS,

COSMETIC AND PHARMA INGREDIENTS

MANUFACTURING INDUSTRY

For

M/s. Somu Organo-Chem Pvt. Ltd.,

#20, 29th main, 1st phase

2ndstage B.T.M layout

Bangalore-76

At

Shed No.C-29, C-30 & adjacent plots

KSSIDC Industrial Estate

Malur-563 130

Kolar District

Environmental Consultants

AQUATECH ENVIRO ENGINEERS

# 3391, 6th Main, 3rd Cross, RPC Layout

Vijayanagar II Stage

Bangalore – 560 040

Tele Phone : 080 23141679

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Contents

Sl. No. Description Pg. no

1 CHAPTER – 1

EXECUTIVE SUMMARY

1-43

1.1 Introduction 1

1.1.1 Preamble 1

1.1.2 Project at a Glance 4

1.1.3 Summary of water, wastewater, air and solid waste details 7

1.1.4 Water requirement and wastewater treatment and discharge details

9

1.1.5 Raw materials 10

1.1.6 Solvent recovery and recycling 30

1.1.7 Air pollution details 34

1.1.8 Noise pollution details 36

1.1.9 Solid waste details 36

1.1.10 Hazardous raw materials used in the manufacturing process 36

1.1.11 Hazardous waste generation and its management during the manufacturing process

37

1. Spent carbon 37

2. Catalyst Details 38

3. Hazardous Waste Generated 40

1.2.2 Environmental management plan during operation phase 42

2 CHAPTER - 2 INTRODUCTION OF THE PROJECT/

BACKGROUND INFORMATION

44-48

2.1 Introduction of project proponent 44

2.2 Brief description about the nature of the project 45

2.3 Need for the project and its importance to the country and/ region

46

2.4 Demand supply gap, imports vs ingredients production 47

2.5 Export possibility 48

2.6 Employment Generation Due To The Project 48

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ii

3 CHAPTER - 3 PROJECT DESCRIPTION

49-168

3.1 Type of project 49

3.2 Location of the industry 49

3.3 Basis of selecting the site 51

3.4 Size/ magnitude of operation 51

3.5 Products manufactured & List of Products with batch cycle time 52

3.5.1 Manufacturing process description 56

3.5.2 Manufacturing process details of each product 56

3.6 Raw materials 129

3.6.1 Storage facility for raw materials & products 149

3.6.2 Machinery and equipment details 150

3.7 Resource optimization/ recycling and reuse envisaged in the project

151

3.7.1 Solvent recovery and reuse 151

3.7.2 Solvent recovery system 152

3.8 Hazardous raw materials used in the manufacturing process 152

3.8.1 Hazardous waste generation & its management 153

3.8.2 Hazardous waste quantity and disposal 154

3.9 Domestic solid waste reuse 155

3.10 Water, energy, power requirement & source 155

3.11 Water demand and wastewater/ effluent discharge 156

3.12 Product wise water consumption and discharge 158

3.13 Product wise Effluent generation 160

3.14 Waste water characteristics 163

3.15 Air pollution sources 164

3.15.1 Scrubbing system details 165

3.16 Noise pollution details 167

3.17 Solid waste details 167

3.18 Overall Feasibility & Environmental Assessment Report 168

4 CHAPTER - 4 SITE ANALYSIS

171-175

4.1 Site Connectivity 169

4.2 Land form, land use and ownership 171

4.3 Topography 171

4.4 Existing land use pattern 172

4.5 Existing infrastructure 172

4.6 Soil classification 172

4.7 Meteorological data 173

4.7.1 Temperature 173

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iii

4.7.2 Relative humidity 173

4.7.3 Rainfall 174

4.7.4 Atmospheric pressure 174

4.7.5 Inversion height 174

4.7.6 Cloud cover 174

4.7.7 Wind 174

4.8 Social infrastructure available 175

5 CHAPTER – 5 PLANNING BRIEF

180-181

5.1 Planning concept 180

5.2 Population projection 180

5.3 Land use planning 180

5.4 Assessment of infrastructure demand 181

5.4.1 Water supply and sewerage infrastructure 181

5.5 Amenities/facilities 181

6 CHAPTER – 6 PROPOSED INFRASTRUCTURE

182-185

6.1 Industrial area (processing area) 182

6.2 Green belt 182

6.3 Social infrastructure 182

6.4 Connectivity 182

6.5 Sewerage system 182

6.6 Industrial waste management 183

6.7 Solid waste management 183

6.8 Power requirement and supply source 183

6.9

7 CHAPTER – 7 REHABILITATION & RESETTLEMENT PLAN

184

8 CHAPTER – 8 PROJECT SCHEDULE & COST ESTIMATES

185

8.1 Time schedule 185

8.2 Estimate project cost 185

9 CHAPTER – 9 ANALYSIS OF PROPOSAL

186

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iv

List of Tables Table

no. Description Pg. no

1.1 Present chemicals being manufactured 2

1.2 Proposed chemicals to be manufactured 2

1.3 Water consumption and discharge 9

1.4 Sewage/wastewater treatment and discharge 10

1.5 Raw Materials Requirement 10

1.6 Solvent Recovery 30

1.7 Sources of air pollution, type of fuel used, APC details 34

1.8 Solid Waste Generation during the Operation Phase 36

1.9 Hazardous raw materials 37

1.10 Quantity of spent Carbon waste generated from manufacturing process

37

1.11 Quantity of catalyst sent to reactivation 38

1.12 Quantity of catalyst generation from process 39

1.13 Types of hazardous waste generated 40

1.14 Environmental Management Plan during Operation Phase 42

3.1 Present & proposed Products to be manufactured 52

3.2 Raw Materials Requirement for production of specialty chemicals 130

3.3 Details of Storage Facilities 149

3.4 List of Machinery 150

3.4a List of Equipments 151

3.4b List of Utilities 151

3.5 Hazardous raw materials 152

3.6 Quantity of spent Carbon waste generated from manufacturing process

154

3.7 Hazardous Waste Quantity and Disposal Details 154

3.8 Water consumption and discharge 156

3.9 Sewage/ effluent treatment and discharge 158

3.10 Product wise water consumption, discharge 158

3.11 Product-wise effluent generation for process 160

3.12 Wastewater characteristics 163

3.13 Air pollution sources, fuel consumption and chimney height details

164

3.14 Solid waste generation 167

4.1 Connectivity from the project site 169

4.2 Existing land use pattern 172

4.3 Meteorological data of Kolar for the year 2015 173

5.1 Land use pattern 180

8.1 Time Schedule 185

8.2 Proposed Expansion Cost 185

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v

List of figures

Fig. No. Description Pg. no

3.1 Google map showing project site 49

3.2 Maps showing and project site location on district map 50

3.3 Water balance chart 157

3.4 Water Jet Scrubber 166

3.6 Feasibility & environmental assessment process 168

4.1 Google map showing connectivity to project site 170

4.2 Topo Map of the project site 171

4.3 Windrose diagrams 176

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 1

1.1 INTRODUCTION

1.1.1 Preamble

Amendment of the Environmental Impact Notification No. S.O. 60(E) dated 27.01.1994,

issued by the MoEF, Govt. of India has made mandatory under Schedule-I of EIA

notification for 30 different activities to obtain CFE from the State Pollution Control Board

and Environmental Clearance from the Ministry of Environment & Forests, Govt. of India.

This amendment to the EIA Notification is effective from 14.09.2006.

As per the amended EIA notification dated 14th September, 2006 the Processing of Fine and

specialty chemicals industry will fall under category B schedule 5(f). The proposed project is

an Expansion project.

M/s. Somu Organo-Chem Pvt. Ltd. at No.20, 29th Main, II Stage, I Phase, BTM Layout, Bangalore-560 076 proposes to expand its process specialty fine chemicals, bulk drugs & cosmetic and pharma ingredients industry at Shed No.C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District. The proposed expansion envisages addition of (29) new products along with the Existing (7)

products which will be manufactured within the existing manufacturing facilities.

The present fine & specialty chemicals manufactured are provided under Table 1.1& 1.2

CHAPTER 1

EXECUTIVE SUMMARY

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 2

Table 1.1 Present fine & specialty chemicals being manufactured Reference No. SEIAA letter No. SEIAA :5: IND 2010, dated 09/06/2010

SI. No. Fine &

Specialty Chemicals

Production capacity (Kg/month)

Production Capacity (Kg/annum)

1 Benzalkonium chloride 1,00,000 12,00,000

2 1,3 Cyclohexanedione 75,000 9,00,000

3 Ore flotation reagent 2,00,000 24,00,000

4 4-Hydroxy carbazole 2,000 24,000

5 2/4 Methylcyclohexanol 5,000 60,000

6 2,4 Thiazolidinedione 10,000 1,20,000

7 3,3,5 Trimethylcyclohexanol 20,000 2,40,000

Total(A) 4,12,000 49,44,000

Table 1.2 Proposed fine & specialty chemicals to be manufactured

SI.NO. Specialty fine Chemicals, bulk drugs, cosmetic and pharma

ingredients

Production capacity (Kg/month)

Production capacity (Kg/annum)

1 4-n Hexylresorcinol 250 3000

2 4-n Butylresorcinol 150 1800

3 EthylhexylTriazone 1000 12000

4 Iscotrizinol 50 600

5 PiroctoneOlamine 1500 18000

6 Tetrahydrocurcumin 125 1500

7 Tetrahydropiperine 125 1500

8 1,4-Cyclohexanedione and

acetal

1000 12000

9 1,4-Cyclohexanediol 500 6000

10 (S)-1-Phenyl-1,2,3,4-

Tetrahydroisoquinoline

1000 12000

11 3-Quinuclidinone hydrochloride 100 1200

12 R-(-)-3-Quinuclidinol 50 600

13 Ethyl isonipecotate 2,500 30000

14 1,2,3,9-Tetrahydro-9-methyl-

4(H)-carbazol-4-one

500 6000

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 3

The total production capacity is A+B= 49,44,000+3,70,860 = 5,314,860 Kg/annum EC to be obtained for total production capacity of 5,314,860 Kg/annum

15 4-(2,3-epoxypropoxy)carbazole 500 6000

16 4-Methoxyethylphenol and

Metoprolol

1,000 12000

17 Mebeverine Amine 1,000 12000

18 2-(2-

Ethoxyphenoxy)ethylbromide

10 120

19 R-1-(-Methoxyphenyl-N-(R)-1-

phenylethyl)propan-2-amine

hydrochloride

15 180

20 R,R-2-methoxy-5-[2-(1-

phenylethylamino)-propyl]

benzenesulfonamide

15 180

21 R-(-)-5-(2-Aminopropyl)-2-

methoxy-benzenesulfonamide

and Tamsulosin

15 180

22 4-Methylcyclohexanone 2,000 24000

23 Trans-4-Methylcyclohexyl amine 500 6000

24 Tris(Hydroxymethyl)aminometh

ane

500 6000

25 Trans-4-aminocyclohexanol 5,000 60000

26 Tranexamic acid 500 600

27 Benzethonium chloride 1,000 12000

28 Cinnamyl alcohol 5,000 60000

29 (R)-(-)-3-Carbamoylmethyl-5-

Methylhexanoic Acid and

Pregablin

5,000 60000

TOTAL(B) 30905 3,70,860

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 4

1.1.2 Project at Glance

Sl.No.

Details

1 Project Expansion process of hydrogenation, formulations and processing of fine and specialty chemicals industry– “M/s. SOMU Organo Chem Pvt. Ltd.,” at Shed No.C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District.

2 Project developers M/s. Somu Organo-Chem Pvt. Ltd. at No.20, 29th Main, II Stage, I Phase, BTM Layout, Bangalore-560 076.

3 Location of the site Shed No. C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District

4 Constitution of the Organization

Private Limited Company

5 Raw materials Details of the raw materials required by the industry is appended in Section 3.6. Chapter 3 of this report.

6 Product/s proposed to be manufactured with production capacities?

The following are proposed to be manufactured Existing 7 products and proposed 29 products

SI. No.

Fine & Specialty Chemicals Production capacity

(Kg/month)

1 Benzalkonium chloride 1,00,000

2 1,3 Cyclohexanedione 75,000

3 Ore flotation reagent 2,00,000

4 4-Hydroxy carbazole 2,000

5 2/4 Methylcyclohexanol 5,000

6 2,4 Thiazolidinedione 10,000

7 3,3,5 Trimethylcyclohexanol 20,000

Total(A) 4,12,000

1 4-n Hexylresorcinol 250

2 4-n Butylresorcinol 150

3 EthylhexylTriazone 1000

4 Iscotrizinol 50

5 PiroctoneOlamine 1500

6 Tetrahydrocurcumin 125

7 Tetrahydropiperine 125

8 1,4-Cyclohexanedione and acetal 1000

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 5

9 1,4-Cyclohexanediol 500

10 (S)-1-Phenyl-1,2,3,4-

Tetrahydroisoquinoline

1000

11 3-Quinuclidinone hydrochloride 100

12 R-(-)-3-Quinuclidinol 50

13 Ethyl isonipecotate 2,500

14 1,2,3,9-Tetrahydro-9-methyl-4(H)-

carbazol-4-one

500

15 4-(2,3-epoxypropoxy)carbazole 500

16 4-Methoxyethylphenol and

Metoprolol

1,000

17 Mebeverine Amine 1,000

18 2-(2-Ethoxyphenoxy)ethylbromide 10

19 R-1-(-Methoxyphenyl-N-(R)-1-

phenylethyl)propan-2-amine

hydrochloride

15

20 R,R-2-methoxy-5-[2-(1-

phenylethylamino)-propyl]

benzenesulfonamide

15

21 R-(-)-5-(2-Aminopropyl)-2-methoxy-

benzenesulfonamide and Tamsulosin

15

22 4-Methylcyclohexanone 2,000

23 Trans-4-Methylcyclohexyl amine 500

24 Tris(Hydroxymethyl)aminomethane 500

25 Trans-4-aminocyclohexanol 5,000

26 Tranexamic acid 500

27 Benzethonium chloride 1,000

28 Cinnamyl alcohol 5,000

29 (R)-(-)-3-Carbamoylmethyl-5-

Methylhexanoic Acid and Pregablin

5,000

TOTAL(B) 30905

The total production capacity is A+B= 4, 12,000 + 30,905=4, 42,905 Kg/month. Or say

5,314,860 Kg/annum

7 Project cost? The estimated project expansion cost would be Rs. 4.34 Crores

8 Total man power Construction phase: Since the proposed project is an existing

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 6

requirement during construction

phase occupancy

phase

industry there is no construction activity envisaged. Operational phase: Existing: 60 employees Proposed: 75employees

9 Proposed trees to be planted?

Trees planted – 52nos Trees proposed to be planted-20 nos

10 Species of trees to be planted?

Silver Wood, Teak wood, Coconut, Asoka Trees, Mango trees, neem, and several native species are found within the project site.

11 Rain water harvesting tank details?

30 KLD Capacity

12 Groundwater recharging pits details?

Storm water recharge pits are provided. The recharge pits are interconnected in such a way that the rain led to the first recharge pit is also led to the next pit.

13 Elevation of the project site with respect to MSL

Latitude 12° 58' 55.88” N Longitude 77° 55' 03.71” E and at 897 m above MSL.

14 Total area of the project

5,532.91SQM (about 1.36 Acres)

15 Ground water quality

Potability of water is tested and can be used for drinking.

16 Noise levels Noise levels are within the standard limits.

17 Facilities provided for the workers during construction phase at site?

As the proposed project is an existing industry, no construction activity is envisaged.

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 7

1.1.3 Summary of Water, Wastewater, air and solid waste details

Sl. No. Particulars Details

A Water, wastewater details

1 Water supply sources Water tankers supply

2 Total water requirement 111KLD(proposed)+17,496LPD(Existing-16KLD industrial+ 1.5 KLD domestic) Total =130KLD

3 Total wastewater generated

34KLD proposed- (31KLD industrial effluent + Domestic 3KLD) + 17KLD (Existing- 16KLD Industrial effluent + 1.2KLD Domestic) Total= 50KLD

4 Treatment/Disposal details Industrial effluent generated is stored in two collection tanks of about 40,000 L capacity each and sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

B Air pollution details

1 Sources of air pollution Process sections, Boiler, DG set

2 Air pollution control units provided

*Flash drier cyclone separator with water jet scrubber is the existing air pollution control equipment and Steam jet ejector & Water ring vacuum pump is proposed for the process section. * A 250 kVA DG set of stack height 5mARL is under operation * Thermic Fluid Heater (TFH) of stack 3m ARL is provided and under operation * Scrubber attached to neutralization tank is under operation * Scrubber & packed fume extraction system attached to laboratory area is under operation. * A 2T/hr Boiler of stack height 30.5m AGL is proposed * Scrubber attached to reactor is proposed * Scrubber & packed fume extraction system attached to R&D lab area is under operation.

C Solid/Hazardous wastes

1 Source of solid waste Domestic sources and Manufacturing process.

2

Total quantity of solid waste generated

Domestic solid waste – 19Kg/annum

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 8

3 Hazardous waste Hazardous solid waste (Existing) Waste

Category No.

Hazardous waste

generated

Quantity

5.1 a) Used oil

b) Vacuum oil

0.15KL/A

0.35KL/A

5.2 Oil soaked cotton waste

b) Oil filters

0.2MT/A

5Nos./A

33.3 Discarded containers

Chemical

contaminated paper & plastic

bags

3600Nos./A

21MT/A

34.3 ETP Sludge 0.4MT/A

Hazardous solid waste (Proposed)

Sl.No. Source Quantity of hazardous

waste generated Kg/month

1 Process Effluent 13,20,950

2 Spent Carbon 867

3 Waste oil from DG

30 liters

4 Spent Solvent 1,44,858

5 HDPE/Discarded containers

1,965Nos.

6 Chemical contaminated

paper & plastic bags

1,340

7 Distillation residue

500

3 Treatment/Disposal of solid wastes

The domestic wastes are segregated at source and collected in bins and handed over to KSSIDC for scientific disposal. The hazardous wastes shall be collected in leak proof containers and disposed only to KSPCB authorized reprocessors with valid authorization for processing and scientific disposal

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 9

1.1.4 Water Requirement and Wastewater Treatment and Discharge Details I) Quantity of

Water Required and Wastewater Generated

The total quantity of water requirement for the industry is about 111KLD. The break-up of the consumption of water is as presented in Table 1.3.

Table 1.3 Water consumption and discharge Water consumed for

Consumption

LPD

Recirculation

/RecycleLPD

Loss/Consumption/Evaporation /Daily Make Up Water Etc. LPD

Discharge

LPD

(a) Domestic 3750 3,750 3,375

(b) Landscape development 5,000 5,000 -

(c) Industrial purpose 1,02,000 74,000 30,450

Softener 43,000 15,000 14,750

a. Process water from Softener

b. Boiler water from Softener

7,631 or say 8,000

35,000

Recirculation water = 35,000-7000 (5250 Evaporation loss +1750 Blow down=28000

7,631 or say 8,000

Evaporation loss + blowdown loss(5250 +1750)=7000

11,000

1,750

(blow down)

Softener rejects 2000

1 Washings 14,000 14,000 14,000

2 Cooling tower 35,000

Evaporation loss + bleed off =(34,300+700)=35,000

700(bleed off)

3 Scrubber(1+1new) 1,000 1,000 1,000

4 Water for steam jet ejector

9,000 9,000 -

Total 1,10,750 28,000 82,750 33,825

LPD = L/day; KLD = kilo liter/day.

Startup water requirement for industrial purpose is110750 LPD or say 111KLD. Daily

requirement after recycling from boiler Condensate: 110750-28000=82750 LPD or say

82KLD

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 10

ii) WASTEWATER TREATMENT AND DISPOSAL DETAILS

The treatment methods and the final disposal of wastewater generated is appended in the

table 1.4

Table 1.4 Sewage/wastewater treatment and discharge

Sewage/effluent generated from

Treatment provided Final disposal point

(a) Domestic Sewage is treated in septic tank Disposed in Soak pit

(b) Industrial - Effluent generated from the industry is sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

1.1.5 Raw Materials The raw materials required for the production are appended in the table 1.5 below. Raw materials as listed will be procured as per the production requirement.

Table -1.5 Raw Materials Requirement

Sl.No. Product Raw materials Quantity Required Solvents

required

after

recycling

kg/annum

Solid/L

iquid

Packing

Kg/

Batch

Kg/

Month

Kg/

Annum

1 4-n-Hexyl

resorcinol

Resorcinol 100 500 6000 - Solid 25kg/

bag

Caproic acid 200 1000 12000 - Liquid 170kg/

drum

Zinc catalyst 10 50 600 - Solid 25kg/

drum

Raney Nickel

catalyst

10 50 600 - Solid 10kg/

drum

Hexane 350 1750 21000 2100 Liquid 140kg/

drum

Methanol 500 2500 30000 3000 Liquid 160kg/

drum

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 11

Nitrogen gas

cylinders

4 20 240 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

5 25 300 - Gas 7cu.m./

cylinder

Water for

process

600 3000 36000 -

Water for

washing

500 2500 30000 -

2 4-n-Butyl

resorcinol

Resorcinol 111 333 3996 - Solid 25kg/

bag

Butyric acid 194 582 6984 - Liquid 170kg/

drum

Zinc catalyst 11 33 396 - Solid 25kg/

drum

Raney Nickel

catalyst

10 30 360 - Solid 10kg/

drum

Hexane 350 1050 12600 1260 Liquid 140kg/

drum

Methanol 500 1500 18000 1800 Liquid 160kg/

drum

Nitrogen gas

cylinders

4 12 144 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

5 15 180 - Gas 7cu.m./

cylinder

Water for

process

600 1800 21600 -

Water for

washing

500 1500 18000 -

3 Ethyl

hexyltriazo

ne

p-Nitrobenzoic

acid

100 667 8004 - Solid 25kg/

bag

2-Ethylhexanol 95 634 7608 - Liquid 170kg/

drum

Sulfuric acid 15 100 1200 - Liquid 50kg/

drum

Page 18: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 12

Sodium

carbonate

30 200 2400 - Solid 50kg/

bag

Toluene 450 3002 36024 3602 Liquid 170kg/

drum

Nitrogen gas

cylinders

4 27 324 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 60 720 - Gas 7cu.m./

cylinder

10% Palladium

on carbon

catalyst

5 33.5 402 - Solid 10kg/

drum

Methanol 600 4002 48024 4002 Liquid 160kg/

drum

Ammonia

solution

6 40 480 - Liquid 190kg/

drum

Perchloroethylen

e

1000 6670 800040 6403 Liquid 250kg/

drum

Cyanuric chloride 35 233.5 2802 - Solid 50kg/

drum

Xylene 400 2668 32016 3202 Liquid 180kg/

drum

Acetonitrile 600 4002 48024 1802 Liquid 150kg/

drum

Activated carbon 5 33.5 402 - Solid 25kg/

bag

Hyflo 5 33.5 402 - Solid 21.2kg/

bag

Water for

process

1600 10672 128064 -

Water for

washing

900 6003 72036 -

4 Isocotrizino

l

p-Nitrobenzoic

acid

48 24 288 - Solid 25kg/ba

g

Thionyl chloride 20 10 120 - Liquid 200kg/d

Page 19: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 13

rum

Toluene 900 450 5400 840 Liquid 170kg/d

rum

Caustic soda lye 30 15 180 - Liquid Tanker

t-Butylamine 29 14.5 174 - Liquid 140kg/d

rum

Triethylamine 33 16.5 198 - Liquid 140kg/d

rum

Potassium

carbonate

38 19 228 - Solid 50kg/ba

g

Methanol 500 250 3000 300 Liquid 160kg/

drum

10% Palladium

on catalyst

3 1.5 18 - Solid 10kg/

drum

Nitrogen gas

cylinders

6 3 36 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

8 4 48 - Gas 7cu.m./

cylinder

Cyanuric chloride 45 22.5 270 - Solid 50kg/

drum

Acetonitrile 255 112.5 1350 150 Liquid 150kg/

drum

Hexane 500 250 3000 300 Liquid 140kg/

drum

Ammonia

solution

41 20.5 246 - Liquid 190kg/

drum

Activated carbon 5 2.5 30 - Solid 25kg/

bag

Hyflo 5 2.5 30 - Solid 21.2kg/

bag

Water for

process

900 450 5400 -

Water for

washing

500 250 3000 -

Page 20: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 14

5 PiroctoneO

lamine

3,3-

Dimethylacrylic

acid

125 1875 22500 - Solid 25kg/dr

um

Methanol 770 11550 138600 12600 Liquid 160kg/d

rum

Sulphuric acid 25 375 4500 - Liquid 50kg/

drum

Sodium

Carbonate

30 450 5400 - Solid 50kg/

bag

Toluene 450 6750 81000 8100 Liquid 160kg/d

rum

Isononanoyl

chloride

250 3750 45000 - Liquid 250kg/d

rum

Ethylene

dichloride

800 12000 144000 14400 Liquid 160kg/d

rum

Aluminium

chloride

500 75000 900000 - Solid 25kg/

drum

Caustic soda lye 400 6000 72000 - Liquid Tanker

Sodium

methoxide

125 1875 22500 - Solid 25kg/ba

g

Acetic acid 125 1875 22500 - Liquid 160kg/d

rum

Hydroxylamine

hydrochloride

190 2850 34200 - Solid 25kg/

drum

Ethylacetate 1250 18750 225000 22500 Liquid 160kg/d

rum

Monoethanol

amine

12.5 187.5 2250 - Liquid 210kg/d

rum

Water for

process

1500 22500 270000 -

Water for

washing

500 7500 90000 -

6 Tetrahydro

curcuminoi

Curcumin 100 167 2004 - Solid 25kg/

drum

Page 21: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 15

ds Acetone 900 1875 22500 2246 Liquid 160kg/dr

um

10% Pd/C

Catalyst

5 10.5 126 - Solid 25kg/

drum

Nitrogen gas

cylinders

5 10.5 126 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 19 228 - Gas 7cu.m./

cylinder

Isopropyl alcohol 450 936 11232 1123 Liquid 170kg/dr

um

Activated carbon 8 17 204 - Solid 25kg/

bag

Hyflo 5 10.5 126 - Solid 21.2kg/

bag

Water for

washing

500 1042 12504 -

7 Tetrahydro

piperine

Piperine 100 167 2004 - Solid 25kg/

drum

Acetone 900 1875 22500 2246 Liquid 160kg/dr

um

10% Pd/C

Catalyst

5 10.5 126 - Solid 25kg/

drum

Nitrogen gas

cylinders

5 10.5 126 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 19 228 - Gas 7cu.m./

cylinder

Isopropyl alcohol 450 936 11232 1123 Liquid 170kg/dr

um

Activated carbon 8 17 204 - Solid 25kg/

bag

Hyflo 5 10.5 126 - Solid 21.2kg/

bag

Water for

washing

500 1042 12504 -

Page 22: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 16

8 1,4-

Cyclohexan

edione and

acetal

Dimethylsuccinat

e

660 6600 79200 - Liquid 200kg/dr

um

Sodium

methoxide

260 2600 31200 - Solid 25kg/bag

Toluene 1000 10000 120000 10800 Liquid 170kg/dr

um

Methanol 250 2500 30000 3600 Liquid 160kg/dr

um

Sulphuric acid 500 5000 60000 - Liquid 50kg/dru

m

Ethyl acetate 700 7000 84000 8400 Liquid 185kg/dr

um

Activated carbon 6 60 720 - Solid 25kg/

bag

Hyflo 5 50 600 - Solid 21.2kg/

bag

Water for

process

5600 56000 672000 -

Water for

washing

500 5000 60000 -

9 1,4-

Cyclohexan

ediol

Hydroquinone 110 550 6600 - Solid 25kg/bag

Isopropyl alcohol 700 3500 42000 4200 Liquid 165kg/dr

um

Ethyl acetate 500 2500 30000 3000 Liquid 185kg/dr

um

Raney Nickel

catalyst

10 50 600 - Solid 10kg/dru

m

Nitrogen gas

cylinders

6 30 360 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

19 95 1140 - Gas 7cu.m./

cylinder

Water for

washing

500 2500 30000 -

10 (S)-1- Phenylethylamin 140 2800 33600 - Liquid 190kg/dr

Page 23: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 17

Phenyl-

1,2,3,4-

Tetrahydro

isoquinolin

e

e um

Benzoyl chloride 100 2000 24000 - Liquid 250kg/dr

um

Sodium

hydroxide flakes

88 1760 21120 - Solid 50kg/bag

Methylene

dichloride

400 8000 96000 9600 Liquid 250kg/dr

um

10 (S)-1-

Phenyl-

1,2,3,4-

Tetrahydro

isoquinolin

e

Phosphorus

pentoxide

108 2160 25920 - Solid 50kg/dru

m

Phosphorous

oxychloride

259 5180 62160 - Liquid 50kg/dru

m

Toluene 300 6000 72000 7200 Liquid

Caustic soda lye 420 8400 100800 - Liquid Tanker

Ethyl acetate 700 14000 168000 19200 Liquid 185kg/dr

um

Methanol 600 12000 144000 16800 Liquid 160kg/dr

um

Sodium

borohydride

20 400 4800 - Solid 40kg/dru

m

Nitrogen gas

cylinders

3 60 720 - Gas 7cu.m./

cylinder

Isopropyl alcohol 1000 20000 240000 24000 Liquid 165kg/dr

um

D-(-)-tartaric acid 82 1640 19680 - Solid 50kg/bag

Water for

process

1200 24000 288000 -

Water for

washing

800 16000 192000 -

11 3-

Quinuclidin

one

hydrochlori

de

Ethyl

isonicotinate

157 210 2520 - Liquid 160kg/dr

um

Methyl

chloroacetate

108 145 1740 - Liquid 50kg/dru

m

Sodium 90 121 2544 - Solid 50kg/dru

Page 24: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 18

carbonate m

Methanol 900 1206 14472 1437 Liquid 160kg/dr

um

10% Palladium

on carbon

catalyst

5 7 84 - Solid 10kg/dru

m

Potassiu-t-

butoxide

112 150 1800 - Solid 50kg/dru

m

Butanol 600 804 9648 958 Liquid 160kg/dr

um

Sulfuric acid 50 67 804 - Liquid 50kg/dru

m

11 3-

Quinuclidin

one

hydrochlori

de

Caustic soda lye 100 134 1368 - Liquid Tanker

Acetone 50 67 804 80 Liquid 160kg/dr

um

Water for

process

900 1200 14400 -

Water for

washing

600 800 9600 -

12 R-(-)-3-

Quinuclidin

ol

3-Quinuclidinone 100 100 1200 - Solid 25kg/dru

m

Methanol 600 600 7200 720 Liquid 160kg/dr

um

Ethyl acetate 400 400 4800 480 Liquid 185kg/dr

um

5% Ruthenium

on carbon

catalyst

4 4 48 - Solid 10kg/dru

m

Nitrogen gas

cylinders

6 6 72 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

6 6 72 - Gas 7cu.m./

cylinder

Methylene

dichloride

200 200 2400 - Liquid 250kg/

drum

Page 25: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 19

Water for

washing

1000 1000 12000 -

13 Ethyl

isonipecota

te

Ethyl

isonicotinate

125 3125 37500 - Liquid 160kg/

drum

Methanol 600 15000 180000 18000 Liquid 160kg/

drum

10% Palladium

on carbon

4 100 1200 - Solid 10kg/

drum

Nitrogen gas

cylinder

6 150 1800 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

14 350 4200 - Gas 7cu.m./

cylinder

Methylene

dichloride

200 5000 60000 6000 Liquid 250kg/

drum

Water for

washing

700 17500 210000 -

14 1,2,39-

Tetrahydro

-9-methyl-

4(H)-

carbazol-4-

one

1,2,3,9-

Tetrahydro-4(H)-

carbazole

125 625 7500 - Solid 25kg/

drum

Methylene

dichloride

700 3500 42000 4200 Liquid 250kg/

drum

Dimethylformami

de

45 225 2700 - Liquid 200kg/

drum

Caustic soda lye 66 330 3960 - Liquid Tanker

Tetrabutylammo

nium bromide

1 5 60 - Solid 25kg/

drum

Water for

process

100 500 6000 -

Water for

washing

500 2500 30000

Page 26: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 20

15 4-(2,3-

Epoxyprop

oxy)-9H-

Carbazole

4-

Hydroxycarbazol

e

200 668 8016 - Solid 25kg/

drum

Epichlorohydrin 236 708 8496 - Liquid 220kg/

drum

Isopropyl alcohol 700 2338 28056 2797 Liquid 165kg/

drum

Caustic soda lye 102 341 4080 - Liquid Tanker

Water for

process

900 3000 36000 -

Water for

washing

500 1667 20004 -

16 4-(2-

Methoxyet

hyl)phenol

Phenol 94 1567 18804 - Liquid 200kg/

drum

Chloroacetyl

chloride

214 3568 42816 - Liquid 220kg/

drum

Aluminium

chloride

267 4451 53412 - Solid 25kg/

drum

Caustic soda lye 300 5001 60012 - Liquid Tanker

Ethylene

dichloride

350 5835 70020 8401 Liquid 220kg/

drum

Hydrochloric acid 400 6668 80016 - Liquid 220kg/

drum

Methanol 1210 20171 242052 24005 Liquid 220kg/

drum

16 4-(2-

Methoxyet

hyl)phenol

and

Metoprolol

Sodium

methoxide

110 1834 22008 - Solid 25kg/

drum

10% Palladium

on carbon

4 67 804 - Solid 10kg/

drum

Nitrogen gas

cylinder

3 50 600 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

5 84 1008 - Gas 7cu.m./

cylinder

Water for 600 10002 120024 -

Page 27: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 21

processing

Water for

washing

800 13336 160032 -

17 Mebeverin

e amine

3,4-

Dimethoxybenzoi

c acid

200 1000 12000 - Solid 25kg/

drum

Methanol 2300 11500 138000 13800 Liquid 160kg/

drum

Sodium

methoxide

60 300 3600 - Solid 25kg/

drum

1-chloro-4-

bromobutane

800 4000 48000 - Liquid 250kg/

drum

Toluene 1100 5500 66000 7800 Liquid 170kg/

drum

4-Methoxyphenyl

acetone

175 875 10500 - Liquid 200kg/

drum

70%Monoethyl

amine

140 700 8412 - Liquid 160kg/

drum

10% Palladium

on carbon

catalyst

5 25 300 - Solid 10kg/

drum

Nitrogen gas

cylinder

6 30 360 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

7 35 420 - Gas 7cu.m./

cylinder

Methyl

isobutylketone

200 1000 12000 - Liquid 165kg/

drum

Anhydrous

sodium sulfate

30 150 1800 - Solid 50kg/

drum

17 Mebeverin

e amine

Water for

process

950 4750 57000 -

Water for

washing

800 4000 48000 -

18 2-(2- 2-Ethoxyphenol 89 9 108 - Liquid 200kg/

Page 28: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 22

Ethoxyphe

noxy)ethyl

bromide

drum

Ethylene

dibromide

180 18 216 - Liquid 250kg/

drum

Caustic soda lye 130 13 156 - Liquid Tanker

Tetrabutyl

ammonium

bromide

10 1 12 - Solid 25kg/

drum

Isopropyl alcohol 200 20 240 24 Liquid 165kg/

drum

Sodium chloride 30 3 36 - Solid 50kg/

bag

Water for

process

1000 100 1200 -

Water for

washing

500 50 600 -

19 R-1-(-

Methoxyph

enyl-N-(R)-

1-

phenylethy

l)propan-2-

amine

hydrochlori

de

4-

Methoxyphenyla

cetone

80 24 288 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 15 180 - Liquid 50kg/

drum

Toluene 540 162 1944 144 Liquid 170kg/

drum

Methanol 2000 600 7200 540 Liquid 160kg/

drum

HCl in isopropyl

alcohol

70 21 252 - Liquid 30kg/

drum

Acetone 1400 420 5040 540 Liquid 160kg/

drum

Raney Nickel

catalyst

25 7.5 90 - Solid 10kg/

drum

Nitrogen gas

cylinders

9 3 36 - Gas 7cu.m./

cylinder

19 R-1-(- Hydrogen gas 7 2 24 - Gas 7cu.m./

Page 29: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 23

Methoxyph

enyl-N-(R)-

1-

phenylethy

l)propan-2-

amine

cylinders cylinder

Water for

washing

800 240 2880 -

20 (R,R)-2-

Methoxy-5-

[2-(1-

phenylethy

lamino)pro

pyl]benzen

e

ssulfonami

de

4-

Methoxyphenyla

cetone

80 30 360 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 19 228 - Liquid 200kg/

drum

Toluene 540 202.5 2430 182 Liquid 170kg/

drum

Methanol 2000 750 9000 684 Liquid 160kg/

drum

HCl in isopropyl

alcohol

70 26 312 - Liquid 30kg/

drum

Acetone 1400 525 6300 684 Liquid 160kg/

drum

Raney Nickel

catalyst

25 9.5 114 - Solid 10kg/

drum

Nitrogen gas

cylinders

9 5 60 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

7 6 72 - Gas 7cu.m./

cylinder

Chlorosulfonic

acid

82 31 372 - Liquid 200kg/

drum

Thionyl chloride 41 15.5 186 - Liquid 220kg/

drum

Chlorofrom 1200 450 5400 456 Liquid 220kg/

drum

Ammonia

solution

440 165 1980 - Liquid 220kg/

drum

Caustic soda lye 100 37.5 450 - Liquid 220kg/

Page 30: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 24

drum

Water for

process

260 97.5 1170 -

Water for

washing

1300 487.5 5850 -

21 R-(-)-5-(2-

Aminoprop

yl)-2-

methoxy-

benzene

sulfonamid

e and

Tamsulosin

4-

Methoxyphenyla

cetone

80 60 720 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 38 456 - Liquid 200kg/

drum

Toluene 540 405 4860 360 Liquid 170kg/

drum

Methanol 2000 1500 18000 2250 Liquid 160kg/

drum

HCl in isopropyl

alcohol

70 52.5 630 - Liquid 30kg/

drum

Acetone 1400 1050 12600 1350 Liquid 160kg/

drum

Raney Nickel

catalyst

25 19 228 - Solid 10kg/

drum

Nitrogen gas

cylinders

14 11 132 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

15 11 132 - Gas 7cu.m./

cylinder

Chlorosulfonic

acid

82 61.5 738 - Liquid 200kg/

drum

Thionyl chloride 41 31 372 - Liquid 200kg/

drum

Chlorofrom 1200 900 10800 900 Liquid 250kg/

drum

Ammonia

solution

440 330 3960 - Liquid 190kg/

drum

Caustic soda lye 100 75 900 - Liquid Tanker

Page 31: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 25

10% Palladium

on carbon

catalyst

15 11 132 - Solid 10kg/

drum

Water for

process

260 195 2340 -

Water for

washing

1500 1125 13500 -

22 4-

Methylcycl

ohexanone

4-

Methylcyclohexa

nol

110 2750 33000 - Liquid 170kg/

drum

Sodium

hypochlorite

solution

744 18600 223200 - Liquid 200kg/

drum

Acetic acid 91 2275 27300 - Liquid 200kg/

drum

Water for

washing

500 12500 150000 - Liquid 220kg/

drum

23 Trans-4-

Methylcycl

ohexyl

amine

4-

Methylcyclohexa

nol

110 1100 13200 - Liquid 170kg/d

rum

Sodium

hypochlorite

solution

744 7440 89280 - Liquid 200kg/d

rum

Acetic acid 91 910 10920 - Liquid 200kg/d

rum

Hydroxylamine

hydrochloride

80 800 9600 - Solid 25kg/

HDPE

drums

Caustic soda lye 165 1650 19800 - Liquid Tanker

Isopropyl alcohol 400 4000 48000 4800 Liquid 170kg/d

rum

Raney Nickel

catalyst

8 80 960 - Solid 10kg/

HDPE

drum

Nitrogen gas 4 40 480 - Gas 7cu.m/c

Page 32: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 26

cylinders ylinder

Hydrogen gas

cylinders

6 60 720 - Gas 7cu.m/c

ylinder

Hydrochloric acid 80 80 960 - Liquid Tanker

Acetone 450 4500 54000 6000 Liquid 160kg/d

rum

n-Butanol 1000 10000 120000 12000 Liquid 160kg/d

rum

Water for

washing

1000 10000 120000 -

24 Tris(Hydrox

ymethyl)a

minometha

ne

Nitromethane 110 550 6600 - Liquid 225kg/dr

um

Paraformaldehyd

e

185 925 11100 - Solid 25kg/bag

Methanol 1400 7000 84000 8400 Liquid 160kg/dr

um

Potassium

hydroxide

0.30 1.5 18 - Solid 50kg/bag

Raney Nickel

catalyst

20 100 1200 - Solid 10kg/bag

Nitrogen gas

cylinders

6 30 360 - Gas 7cu.m/cy

linder

Hydrogen gas

cylinders

10 50 600 - Gas 7cu.m/cy

linder

Activated carbon 5 25 300 - Solid 25kg/

bag

Hyflo 5 25 300 - Solid 21.2kg/

bag

Water for

process

300 1500 18000 -

Water for

washing

600 3000 36000 -

25 Trans-4-

Aminocyclo

Paracetamol 200 10000 120000 - Solid 50kg/

bag

Page 33: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 27

hexanol Isopropyl alcohol 1200 60000 720000 72000 Liquid 160kg/dr

um

Raney Nickel

catalyst

12 600 7200 - Solid 10kg/

bag

Nitrogen gas

cylinder

7 350 4200 - Gas 7cu.m/cy

linder

Hydrogen gas

cylinder

19 950 11400 - Gas 7cu.m/cy

linder

Caustic soda lye 128 6400 76800 - Liquid 160kg/dr

um

Toluene 1200 60000 720000 72000 Liquid 160kg/dr

um

Activated carbon 5 250 3000 - Solid 25kg/

bag

25 Trans-4-

aminocyclo

hexanol

Hyflo 5 250 3000 - Solid 21.2kg/

bag

Water for

process

200 10000 120000 -

Water for

washing

600 30000 360000 -

26 Tranexamic

acid

p-Cyanobenzoic

acid

100 1000 12000 - Solid 25kg/dr

um

Raney Nickel

catalyst

10 100 1200 - Solid 10kg/dr

um

Methanol 900 9000 108000 10800 Liquid 160kg/d

rum

Nitrogen gas

cylinders

14 140 1680 - Gas 7cu.m/

cylinder

Hydrogen gas

cylinders

28 280 3360 - Gas 7cu.m/

cylinder

Ammonia

solution

100 1000 12000 - Liquid 200kg/d

rum

5% Ruthenium

on carbon

5 50 600 - Solid 10kg/dr

um

Page 34: PRE-FEASIBILITY REPORT FOR THE EXPANSION OF …environmentclearance.nic.in/writereaddata/FormB/TOR/PFR/30_Nov... · COSMETIC AND PHARMA INGREDIENTS MANUFACTURING INDUSTRY For M/s.

M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 28

catalyst

Hydrochloric acid 80 800 9600 - Liquid Tanker

Sulphuric acid 5 50 600 - Liquid 50kg/dr

um

Caustic soda lye 50 500 6000 - Liquid Tanker

Activated carbon 4 40 480 - Solid 25kg/

bag

Hyflo 4 40 480 - Solid 21.2kg/

bag

Water for

process

1200 12000 144000 -

Water for

washing

900 9000 108000 -

27 Benzethoni

um

chloride

p-t-Octylphenol 206 824 9888 - Solid 25kg

/bag

Caustic soda lye 276 1104 13248 - Liquid Tanker

Benzyltrimethyla

mmonium

chloride

20 80 960 - Solid 25kg/

drum

Toluene 3000 12000 144000 14400 Liquid 170kg/d

rum

2-Chloroethanol 121 484 5808 - Liquid 200kg/d

rum

Benzylchloride 91 364 4368 - Liquid 230kg/d

rum

Dimethylaminoet

hylchloride

hydrochloride

216 864 10368 - Solid 25kg/

bag

Water for

process

1000 4000 48000 -

Water for

washing

1000 4000 48000 -

28 Cinnamylal

chol

Cinnamaldehyde 111 5550 66600 - Liquid 200kg/d

rum

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Pre-Feasibility Report 29

Methanol 666 33300 399600 39600 Liquid 160kg/d

rum

Sodiumborohydri

de

33 1650 19800 - Solid 30kg/

drum

Hydrochloric acid 100 5000 60000 - Liquid Tanker

Water for

washing

500 25000 300000 -

29 R-(-

)Carbamoyl

methyl-5-

methylhex

anoic acid

and

Pregablin

Isovareldehyde 121 6050 72600 - Liquid 160kg/d

rum

Ethyl

cyanoacetate

160 8000 96000 - Liquid 200kg/d

rum

Di-n-propylamine 10 500 6000 - Liquid 140kg/d

rum

Diethyl malonate 217 10850 130200 - Liquid 200kg/d

rum

Hexane 900 45000 540000 60000 Liquid 140kg/d

rum

Urea 80 4000 48000 - Solid 25kg/ba

g

Caustic soda lye 93 4650 55800 - Liquid Tanker

Chloroform 1000 50000 600000 60000 Liquid 250kg/d

rum

R-(+)-

Phenylethylamin

e

70 3500 42000 - Liquid 200kg/d

rum

Hydrochlroic acid 73 3650 43800 - Liquid Tanker

Water for

process

500 25000 300000 -

Water for

washing

500 25000 300000 -

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Pre-Feasibility Report 30

1.1.6 Solvent Recovery and Recycling

Various solvents are used during the manufacturing process. The solvents proposed to be recovered and recycled during the process of recovering the solvent of such products are detailed in table 1.6 below.

Table 1.6 Solvent Recovery

Sl.No Product Raw materials

(Solvent)

Quantity of Solvent (kg/annum)

Recovered and Recycled

Lost

1. 4-n-Hexylresorcinol

Hexane 18900 2100

Methanol 27000 3000

2. 4-n-Butylresorcinol

Hexane 11340 1260

Methanol 16200 1800

3. Ethyl hexyltriazone

Toulene 32422 3602

Methanol 44022 4002

Xylene 28814 3202

Acetonitrile 46222 1802

Perchloroethylene 793637 6403

4. Isocotrizinol

Acetinitrile 1200 150

Hexane 2700 300

Methanol 2700 300

Toulene 72900 8100

5. Piroctoolamine

Ethylene di chloride 129600 14400

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Pre-Feasibility Report 31

Methanol 126000 12600

Ethyl acetate 202500 22500

6. Tetrahydrocurcuminoids

Acetone 20254 2246

Iso Propyl Alcohol 10129 1123

7. Tetrahydropiperine

Acetone 20254 2246

Iso Propyl Alcohol 10129 1123

8. 1,4-Cyclohexanedione and

acetal Toulene 109200 10800

Methanol 26400 3600

Ethylacetate 75600 8400

9. 1,4-Cyclohexanediol

Iso Propyl Alcohol 37800 4200

Ethylacetate 27000 3000

10. (S)-1-Phenyl-1,2,3,4-

Tetrahydroisoquinoline Methylene Dichloride 86400 9600

Toulene 64800 7200

Ethylacetate 148800 19200

Methanol 127200 16800

Iso Propyl Alcohol 216000 24000

11. 3-Quinuclidinone

hydrochloride Methanol 13035 1437

Butanol 8690 958

Acetone 724 80

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12. R-(-)-3-Quinuclidinol

Methanol 6480 720

Ethylacetate 4320 480

13. Ethyl isonipecotate

Mehanol 162000 18000

Methylene Di Chloride 54000 6000

14. 1,2,39-Tetrahydro-9-

methyl-4(H)-carbazol-4-

one

Methylene Di Chloride 37800 4200

15. 4-(2,3-Epoxypropoxy)-9H-

Carbazole Isopropyl Alcohol 25259 2797

16. 4-(2-Methoxyethyl)phenol

and Metoprolol Ethylene Dichloride 61619 8401

Methanol 240150 24005

17. Mebeverine amine

Methanol 124200 13800

Toulene 58200 7800

18. 2-(2-Ethoxyphenoxy)ethyl

bromide Isopropyl Alcohol 216 24

19. R-1-(-Methoxyphenyl-N-

(R)-1-phenylethyl)propan-

2-amine hydrochloride

Toulene 1800 144

Methanol 6660 540

Acetone 4500 540

20. (R,R)-2-Methoxy-5-[2-(1-

phenylethylamino)propyl]b

enzene ssulfonamide

Toulene 2248 182

Methanol 8316 684

Acetone 5616 684

Chloroform 4944 456

21. R-(-)-5-(2-Aminopropyl)-2-

methoxy-benzene

sulfonamide and

Tamsulosin

Toulene 4500 360

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Methanol 15750 2250

Acetone 11250 1350

Chloroform 9900 900

22. ----------

23. Trans-4-Methylcyclohexyl

amine Isopropyl Alcohol 43299 4800

Acetone 48000 6000

n-butanol 120000 12000

24. Tris(Hydroxymethyl)amino

methane Methanol 75600 8400

25. Trans-4-

Aminocyclohexanol Isopropyl Alcohol 648000 72000

Toulene 648000 72000

26. Tranexamic acid

Methanol 97200 10800

27. Benzethonium chloride

Toulene 129600 14400

28. Cinnamylalchol

Methanol 360000 39600

29. R-(-)Carbamoylmethyl-5-

methylhexanoic acid and

Pregablin

Hexane 480000 60000

Chloroform 540000 60000

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Pre-Feasibility Report 34

1.1.7 Air Pollution Details

The major air pollution sources from the industry are DG set and process sections. These sources are provided with stacks of adequate height so as to disperse the emanating flue gases containing SPM, oxides of sulfur and nitrogen without affecting the ground level concentrations and packed column scrubbers are provided to the process sections with adequate stack height as per the regulatory requirements.

The sources of air pollution, type of fuel used, fuel consumption and chimney heights for each of the air pollution sources of the proposed project are indicated in the following table 1.7.

Table 1.7 Sources of air pollution, type of fuel used, APC details

SI. no.

Stack attached to

Fuel used Fuel consumption

Number of

stacks

Stack/s height

Air pollution control unit

Predicted emissions

1. Process (attached to reactors)

- - 1 5 m ARL

Scrubber Acid mist / VOCs

2. Attached to R&D lab

- - 1 5 m ARL

Scrubber & packed

fume extraction

system

Acid mist

3. Boiler 2T/hr. (proposed)

Wood/Agro waste

300Kg/hr 1 30.5m AGL

Stack SOx, NOx,SPM

Air Pollution Sources and Control (EXISTING) Chim

No.

Chimney

attached to

Minimum

chimney height

to be provided

above ground

level

Rate of

emission

Nm3/Hr.

Constituents

to be

controlled

in the

emission

Tolerance

Limits

mg/Nm3

Air pollution

Control equipment

to be installed, in

addition to

chimney height as

per Col.(3)

1. HSD fired

Thermic Fluid

Heater 2lakh

K.Cal/Hr.

13m AGL - SO2 - -

2. Process/Flash

drier 5m ARL - Acid mist

VOCs

35 Cyclone separator

with water jet

scrubber

3. 250KVA DG

set 5m ARL - SO2 - Acoustic

enclosures

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Pre-Feasibility Report 35

4. Attached to

Laboratory

Area

3m ARL - Acid Mist 50 Scrubber & packed

fume extraction

system

5. Attached to

Neutralizing

Tanks (8Nos.)

3m ARL - Acid Mist 50 Scrubber

6. HSD fired

Thermic Fluid

Heater 2lakh

K.Cal/Hr.

13m AGL - SO2 - -

7. Process/Flash

drier 5m ARL - Acid mist

VOCs

- Cyclone separator

with water jet

scrubber

The exhaust temperature will be nearly ambient and adequate port holes with access platform will be provided as per KSPCB guidelines as under

1. Location of port holes and approach platform

The sampling porthole will be provided at a distance equal to at least eight times the stack diameters downstream and two diameters upstream from source of low disturbance such as bend, expansion, and construction valve fitting or visible flame for rectangular stacks. The equivalent diameter is calculated from the following equation

Equivalent diameter = 2 (Length x Width) (Length x Width)

2. The diameter of the sampling port will be minimum 3”. Arrangement will be made to close the port hole firmly during the period when it is not used for sampling.

3. An easily accessible platform will be provided to accommodate 3 to 4 persons to conveniently sample stack emissions from the portholes.

Ambient air quality and stack emission monitoring

Ambient air quality monitoring will be conducted once in a month as per the guidelines for SPM, SO2, NOx and CO and the record of monitoring reports will be maintained and made available to authorities. Similarly stack monitoring will also be conducted for SPM, SO2, NOx and CO.

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Pre-Feasibility Report 36

1.1.8 Noise pollution details

The major sources of noise pollution in the industry are the DG set, thermic fluid heater, flash drier cyclone separator with water jet scrubber for which acoustic enclosures are proposed. Also ambient noise levels will be maintained by developing vegetation along the periphery and at various locations within the industry premises. 1.1.9 Solid waste details The quantity of solid waste generated from the proposed industry is detailed in the following table 1.8.

Table: 1.8 Solid Waste Generation during the Operation Phase

Details Existing Proposed

Total no. of employees 60 75

Assuming per capita solid waste generation rate as 0.25 kg/capita/day

Quantity of solid waste generated 15kg/day 19 Kg/day

Organic solid waste : 60 % of the total waste 9kg/day 12 kg/day

Inorganic solid waste : 40 % of the total waste 6kg/day 7 kg/day

The domestic wastes are segregated at source and collected in bins and handed over to KSSIDC for scientific disposal.

1.1.10 Hazardous Raw Materials Used in the Manufacturing Process

The following raw materials used during the process of hydrogenation, formulations and processing of fine and specialty chemicals are hazardous in nature according to Hazardous Wastes (Management & Handling) Rules, 1989, (as amended on 24-9-2008), Schedule-1

Table: 1.9 Hazardous raw materials Hazardous raw material Sl. No. as per Manufacture, Storage and Import of Hazardous

Chemical (Amendment) Rules, 19th January, 2000, Schedule I,

Part II

Acetic acid 2

Acetone 4

Aluminium chloride 23

Ammonia solution 31

Benzoyl chloride 65

Benzyl chloride 67

Chlorosulfonic acid 136

Epichlorohydrin 239

Ethyl hexanol-2 254

Ethylene dibromide 263

Hexane 306

Hydrogen 314

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Pre-Feasibility Report 37

Hydroquinone 319

Isopropyl alcohol 334

Methanol 377

Methyl isobutylketone 388

Nitrogen 429

Perchloroethylene 479

Phenol 481

Phosphorous oxychloride 504

Phosphorous pentaoxide 505

Potassium hydroxide 522

Sodium hydroxide 571

Sulphuric acid 591

Thionyl chloride 620

Triethylamine 652

1.1.11 Hazardous Waste Generation and Its Management during the Manufacturing Process

The hazardous wastes generated during the process of hydrogenation, formulations and

processing of fine and specialty chemicals are stored at hazardous waste storage area and sent

to authorize processers. The quantities of hazardous waste generated from various processes

are shown in the following tables 1.10.

1. Spent Carbon

Table: 1.10 Quantity of spent Carbon waste generated from manufacturing process

Si.No. Product Spent Carbon generated Kg/Batch

1 Ethyl hexyltriazone 10

2 Isocotrizinol 10

4 Tetrahydrocurcuminoids 13

5 Tetrahydropiperine 13

6 1,4-Cyclohexanedione and acetal 11

7 Tris(Hydroxymethyl)aminomethane 10

8 Trans-4-Aminocyclohexanol 10

9 Tranexamic acid 8

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Pre-Feasibility Report 38

2. Catalyst Details – sent to Reactivation / Returned to supplier Table: 1.11 Quantity of catalyst sent to reactivation

Sl.No. Product Catalyst Quantity

Kg/Batch Kg/month Kg/Annum

1 4-n-Hexyl resorcinol

Raney Nickel catalyst 10 50 600

Zinc catalyst 10 50 600

2 4-n-Butyl resorcinol Raney Nickel catalyst 10 30 360

Zinc catalyst 10 30 360

3 Ethyl hexyltriazone 10% Palladium on carbon catalyst

5 33.5 402

4 Isocotrizinol 10% Palladium on carbon catalyst

3 1.50 18

5 Tetrahydrocurcuminoids 10% Palladium on carbon catalyst

5 10.5 126

6 Tetrahydropiperine 10% Palladium on carbon catalyst

5 10.5 126

7 1,4-Cyclohexanediol Raney Nickel catalyst 10 50 600

8 3-Quinuclidinone hydrochloride

10% Palladium on carbon catalyst

5 7 84

9 R-(-)-3-Quinuclidinol 5%Rutheniumon carbon catalyst

4 4 48

10 Ethyl isonipecotate 10% Palladium on carbon catalyst

4 100 1200

11 4-(2-Methoxyethyl)phenol and Metoprolol

10% Palladium on carbon catalyst

4 67 804

12 Mebeverine amine 10% Palladium on carbon catalyst

5 25 300

14 R-1-(-Methoxyphenyl-N-(R)-1-phenylethyl)propan-2-amine

Raney Nickel catalyst 25 7.5 90

15 (R,R)-2-Methoxy-5-[2-(1-phenylethyla

mino)propyl]benzene sulfonamide

Raney Nickel catalyst 25 9.5 114

16 R-(-)-5-(2-Aminopropyl)-2-methoxy-benzene sulfonamide

and Tamsulosin

Raney Nickel catalyst 25 19 228

10% Palladium on carbon catalyst

15 11.5 138

17 Trans-4-Methylcyclohexyl amine

Raney Nickel catalyst 8 80 960

18 Tris(Hydroxymethyl)aminomethane

Raney Nickel catalyst 20 100 1200

19 Trans-4-Aminocyclohexanol Raney Nickel catalyst 12 600 7200

20 Tranexamic acid Raney Nickel catalyst 10 100 1200

5% Ruthenium on carbon catalyst

5 50 600

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Pre-Feasibility Report 39

Overall Quantity taken from above table. TABLE: 1.12 QUANTITY OF CATALYST GENERATION FROM MANUFACTURING PROCESS

Sl.No. Catalyst Quantity generated – sent for reactivation / Returned back to supplier

Kg/month Kg/Annum

1 Zinc catalyst 80 960

2 Raney Nickel catalyst 1046 12552

3 10% Palladium on carbon catalyst 266.5 3198

4 5% Ruthenium on carbon 54 648

Activated Carbon Sl.No. Product Quantity Required

Kg/Batch Kg/month Kg/Annum

1 Ethyl hexyltriazone 5 33.5 402

2 Isocotrizinol 5 2.5 30

4 Tetrahydrocurcuminoids 8 17 204

5 Tetrahydropiperine 8 17 204

6 1,4-Cyclohexanedione and acetal 6 60 720

7 Tris(Hydroxymethyl)aminomethane 5 25 300

8 Trans-4-Aminocyclohexanol 5 250 3000

9 Tranexamic acid 4 40 480

Total 445 5370

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Pre-Feasibility Report 40

3). OTHERS: THE VARIOUS HAZARDOUS WASTE GENERATED FROM THE INDUSTRY IS PRESENTED IN TABLE 1.7

TABLE: 1.13 MISCELLANEOUS TYPES OF HAZARDOUS WASTE GENERATED (PROPOSED) Si. No. Source Category Quantity of

hazardous waste generated Kg/month

Disposal Options

1. Spent Carbon 28.2 867 Disposed through Cement industries for co incinerations

2. Waste oil from DG 5.1 30 liters Disposed through authorized recyclers

3. Spent Solvent 28.1 1,44,858 Disposed through KSPCB authorized

dealers

4. HDPE/Discarded containers 33.3 1,965Nos. Disposed through authorized recyclers

5. Chemical contaminated paper & plastic bags

33.3 1,340kg/month Disposed through authorized recyclers

6. Distillation residue sludge 34.3 500kg/month Stored in a secure manner and handed over to TSDF

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Pre-Feasibility Report 41

MISCELLANEOUS TYPES OF HAZARDOUS WASTE GENERATED (EXISTING)

Waste category

Hazardous waste generated

Quantity Method of Handling

5.1

a)Used oil b)Vacuum oil

0.15KL/A 0.35KL/A

Shall be collected in leak-proof containers and disposed only to KSPCB registered authorized re-processors provided the oil meets the standards as per Schedule-5 Part-A of the Rules

5.2 a)Oil soaked cotton waste b)Oil filters

0.2MT/A 5Nos./A

Shall be stored in a secured manner and handed over to KSPCB authorized incinerator/co-processing in cement kiln.

33.3 Discarded containers Chemical contaminated paper & plastic bags

3600Nos./A 21MT/A

Stored in a secured manner and handed over to KSPCB authorized recycler after wash only

34.3 ETP sludge 0.4MT/A Stored in secure manner and handed over to KSPCB authorized to TDSF

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Table 1.14 Environmental Management Plan during Operation Phase

Sl. no.

Environmental components

Predicted impacts Probable source of impact Mitigation measures Remarks

1 Ambient air quality

Minor negative impact.

Process of manufacture of APIs

Particulate and gaseous emissions from DG set and boiler

Vehicular Movement

Manufacturing process involves closed operations in various controlled reactors.

The process area is provided with abundant natural light and ventilation and high roofs to disperse the fumes/gases to the outside atmosphere; preventing the increase of ground level concentrations (GLC’S) as it gets dispersed.

Flash drier cyclone separator with water jet scrubber) for the process areas are installed to neutralize and control dust and fumes from the process section.

The treated waste gases and fumes will be let out through adequate stack height.

The emissions from DG will be let out through adequate stacks height

Orderly Movement of Vehicles will done in the premises.

The roads are made of tar and regularly water sprinkling will be done to control fugitive emissions.

DG sets will be used only during power failure.

2 Noise Minor negative impact near noise generation sources inside the premises.

Operation of machineries during the manufacturing process.

Handling and conveying of raw

The conveying system shall be maintained by following routine and periodic maintenance to reduce noise generation in material handling.

DG set with prebuilt acoustic enclosure as per CPCB norms is installed in

-

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Pre-Feasibility Report 43

materials and semi-finished components to different areas of operations

Operation of DG set.

dedicated utility area, where the access will be restricted. Also the use of PPE (ear plugs) will be mandatory in this area.

Green belt at the project boundary will act as noise barrier and help in attenuation of noise.

3 Water quality No significant adverse impact

Discharge of and industrial effluent

Domestic sewage treated in septic tank and soak pit.

The effluent generated from the manufacturing process will be sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

Water conservation measures will be encouraged.

4 Land No negative impact

Discharge of wastewater.

Storage and disposal of solid wastes.

Domestic sewage will be treated in septic and sent to soak pit. The effluent generated from the

manufacturing process will be sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

-

5 Socio-economic Overall positive impact

Employment opportunities Locally available man power will be utilized to the maximum possible extent.

-

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Pre-Feasibility Report 44

CHAPTER 2

INTRODUCTION OF THE PROJECT/ BACKGROUND INFORMATION

2.1 INTRODUCTION OF PROJECT PROPONENT

Somu group of companies are Manufacturers and Exporters of specialty fine chemicals,

specialty solvents, Pharma Intermediates, Agro Intermediates, Cosmetic ingredients and

nutraceutical ingredients. Also Importers, stockists and Distributors for solvents, Industrial

Chemicals and packaging products.

Headquartered in Bangalore, India, Somu & Co the parent company of Somu Group was

started in the year 1973 under the Stewardship of Mr.C.Somashekar, Chairman & Managing

Director of the group.

Currently leaders in manufacturing specialty fine chemicals, specialty solvents, Pharma

Intermediates, Agro intermediates, Cosmetic ingredients and Nutraceutical ingredients with

the "state of the art manufacturing" units, specialized in Hydrogenation under high

pressure, Esterification and Extraction processes. Also, Importers and Distributors for

petrochemical solvents, Industrial chemicals and packaging products and represent leading

industrial houses and Multinational companies for various products with marketing offices

at Chennai, Hosur, Hyderabad and Cochin.

Somu Organo-Chem Pvt. Ltd., was established in the year 1995 with a manufacturing unit

at Malur near Bangalore to manufacture Specialty Fine Chemicals, Bulk drugs, Cosmetic and

Pharma Ingredients, Perfumery and flavor Intermediates, Agro Chemical Intermediates,

Mining Chemicals and Flotation Reagents.

Specialized in the Hydrogenation under high pressure processes, Hydrogenation, Oxidation,

Condensation, Distillation, Esterifica

tion & Crystallization are some of the chemical operations based on which chemicals are

processed and formulated in the industry. The company is certified with ISO 14001:2004 –

EMS, b. ISO 9001:2008 – QMS & c. ISO 18001:2007 – OSHAS

M/s. Somu Organo-Chem Pvt. Ltd. now envisages expansion of its existing industry with

addition of new products to its process line.

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Pre-Feasibility Report 45

2.2 A Brief note on Fine and Specialty Chemicals

Fine chemicals are complex, single, pure chemical substances, produced in limited quantities in

multipurpose plants by multistep batch chemical processes.

They are used as starting materials for specialty chemicals, particularly in pharmaceuticals.

However, a significant portion of the fine chemicals total production volume is manufactured in

house by large users. The industry is fragmented and extends from small, privately owned

companies to divisions of big, diversified chemical enterprises. The term "fine chemicals" is

used in distinction to "heavy chemicals", which are produced and handled in large lots and are

often in a crude state.

Speciality chemicals are usually manufactured in batch chemical plants using batch processing techniques. Batch process is one in which a defined quantity of product is made from a fixed input of raw materials during a measured period of time. The batch process most often consists of introducing accurately measured amounts of starting materials into a vessel followed by a series of processes involving mixing, heating & cooling, making more chemical reactions, distillation, crystallization, separation, drying, packaging etc., taking place at predetermined and scheduled intervals. The manufacturing processes are supported by activities such as the quality testing, storage& warehousing, and management by recycling, treatment and disposal of by-products, and waste streams. For the next “batch” the equipment may be cleaned and the above processes repeated.

Most speciality chemicals are organic chemicals that are used in a wide range of every day products used by consumers and industry. It is a consumer driven sector and as such the specialty chemical industry has to be innovative, entrepreneurial and consumer-driven. In contrast to the production of commodity chemicals that are usually made on large scale single product manufacturing units to achieve economies of scale, specialty manufacturing units are required to be flexible because the products, raw materials, processes &, operating conditions and equipment mix may change on a regular basis to respond to the needs of customers.

Fine & specialty chemicals cover the manufacture of specialty products used in everything from adhesives, sealants and coatings to pharmaceuticals, detergents and electronic goods.

Highly complex with a huge portfolio of patented technologies, this sector is under growing pressure to meet increasingly stringent safety and environmental regulations and hone competitiveness, particularly as more and more fine chemicals are evolving into commodities.

Manufacturers are challenged to constantly innovate in the search for environmentally cleaner reactions and smart solutions to highly specialised problems.

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The process of hydrogenation involves the use of hydrogen molecules to saturate organic compounds, in the presence of a catalyst. Catalysts are species that are used to speed up the rate of a reaction without being consumed during the process. Keep in mind that catalysts are essential to running this reaction. Common catalysts used during hydrogenation are metals such as nickel and platinum.

An important requirement in the hydrogenation process, besides a catalyst, is the presence of a hydrogen atom. The purpose of the hydrogen atom is to come in and remove the double or triple bond between atoms. In other words, hydrogen atoms turn an unsaturated hydrocarbon into a saturated one.

Saturated Versus Unsaturated Hydrocarbons

Saturated hydrocarbons are compounds that only contain single bonds in their structure. The perfect example of a saturated hydrocarbon is the alkane functional group. Alkanes are organic compounds that contain single bonds between its carbon and hydrogen atoms.

Unsaturated hydrocarbons are compounds that contain double bonds in their structure. The alkene functional group is a great example of an unsaturated hydrocarbon. Alkenes contain at least one double bond between the carbon atoms in its structure. Examples of both saturated and unsaturated hydrocarbons are shown here.

Formulation: Is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product.

2.3 NEED FOR THE PROJECT AND ITS IMPORTANCE TO THE COUNTRY AND/REGION Bulk drugs have become a part of our life for sustaining many of our day-to-day activities, preventing and controlling diseases. Bulk drugs manufacturing sector in India is well established and has recorded a steady growth in the overall Indian industrial scenario. The bulk drugs and allied industries have been amongst the fastest growing segments of the Indian industry.

The Indian Pharmaceutical Industry today is in the front rank of India’s science-based industries with wide ranging capabilities in the complex field of drug manufacture and technology. It is expected to reach a level of Rs 3200 billion by 2012. It ranks very high in the third world, in terms of technology, quality and range of medicines manufactured. From simple headache pills to sophisticated antibiotics and complex cardiac compounds, almost every type of medicine is now made indigenously.

Playing a key role in promoting and sustaining development in the vital field of medicines, Indian Pharma Industry boasts of quality producers and many units approved by regulatory authorities in USA and UK. International companies associated with this sector have stimulated, assisted and spearheaded this dynamic development in the past years and helped to put India on the pharmaceutical map of the world.

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India's pharmaceutical industry is the third largest in the world in terms of volume. Its rank is 14th in terms of value. India is also one of the top five active pharmaceutical ingredients (API) producers (with a share of about 6.5 per cent).

The pharmaceutical industry in India meets around 70% of the country's demand for bulk drugs, drug intermediates, chemicals, tablets, capsules, orals and injectibles. Between September 2008 and September 2009, the total turnover of India's pharmaceuticals industry was US $21.04 billion. The domestic market was worth US $12.26 billion. This was reported by the Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers. As per a report by IMS Health India, the Indian pharmaceutical market reached US $10.04 billion in size in July 2010. A highly organized sector, the Indian Pharma Industry is estimated to be worth $4.5 billion, growing at about 8 to 9 percent annually.

The pharmaceutical industry in Karnataka contributes Rs. 350 crore in revenue to the State exchequer and provides employment for 12,000 people. Its growth rate is between 10-12 percent as against the national pharma growth of 12-14 percent. Pharma products worth Rs. 2,000 crore are produced annually, which is 10 percent of the national production. The exports sales are Rs.850 crore which is 8 percent of Indian exports. International pharma majors have preferred many companies from the State. When large companies offer their services on contractual basis to global MNCs, they want to outsource drug production for the domestic market from quality small-medium manufacturers in State. Here the small-medium units ideally fit into slot as third party manufacturers and serve as a major hubs for pharmaceutical outsourcing. In fact, two of Indian pharma sectors top five brands, are already outsourced from Karnataka. The units have been recognized for stringent regulatory enforcement and known to manufacture quality products. Another added advantage favoring the State is that it is emerging as an investment destination. Hence the proponents have proposed the expansion of their specialty chemicals, bulk drugs, cosmetic and pharma ingredients manufacturing industry - M/s. Somu Organo-Chem Pvt. Ltd.,Shed No. C-29, C-30 & adjacent plots, KSSIDC Industrial Estate,Malur- 563 130, Kolar District 2.4 DEMAND SUPPLY GAP, IMPORTS vs INDIGENOUS PRODUCTION Indian pharmaceutical companies supply almost all the country's demand for API and nearly 70 per cent of demand for bulk drugs. The imports of pharmaceuticals are estimated at 10 to 12 percent of the total market. The major suppliers are Switzerland, China, USA, Germany, Italy, Denmark, France, and UK. Imports include raw materials and finished products. Some major pharmaceuticals which are imported include Provitamins and Vitamins, Cortisones, Hydrocortisone, Insulin, Penicillin, Osetrogen, Progesterone and other hormones, Erythromycin and other ANTIBIOTICS, Antisera & other blood fraction, and Glycosides.

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The imports are from Switzerland, US and Germany primarily consist of finished medicament in dosage forms for retail sales. 2.5 EXPORT POSSIBILITY: The size of the domestic pharmaceutical market is larger than export market. However, owing to the growth of global generics market, stringent price controls in the domestic market, and better margins, the export market is growing much faster than the domestic market. India exports pharmaceuticals to numerous countries around the world, including to the U.S., Germany, France, Russia and UK. The Indian pharmaceutical industry ranks 17th with respect to exports value of bulk actives and dosage. Exports constitute nearly 40 per cent of the production, with bulk drugs 45 per cent. According to the Pharmaceutical Export Promotion Council (Pharmexcil), the pharmaceutical exports in 2007-08 stood at US $6.68 billion against US $5.73 billion in 2006-07, recording a growth rate of 16 per cent. The industry has been clocking export growth rate, recording 18 per cent, 23 per cent and 17 per cent growth rates during 2006-07, 2005-06, and 2004-05, respectively. The overall pharmaceutical exports are estimated to increase at a CAGR of 30-32 percent and reach US $ 18.3 billion in 2010 - 11. 2.6 EMPLOYMENT GENERATION DUE TO THE PROJECT The total direct employment potential of the proposed industry is about 75 people. The existing number of workers being 60, the industry proposes to increase it to 75. However, there are indirect employment generation due to the project during the transportations, marketing & distribution etc.

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CHAPTER 3

PROJECT DESCRIPTION

3.1 TYPE OF PROJECT The proposed project is expansion of hydrogenation, formulations and processing of fine and specialty chemicals. The existing total production capacity of the industry is 49,44,000Kg/annum for which EC is obtained. Reference No. SEIAA letter No. SEIAA :5: IND 2010, dated 09/06/2010.

The industry now proposes the expansion of the production capacity from 49,44,000 Kg/annum

to 5,314,860Kg/annum by the addition of 3,70,860 Kg/annum.

3.2 LOCATION OF THE INDUSTRY

Fig 3.1 Google Map Showing Project Site

897 m above MSL; Latitude: 12°58’'56.71"N; Longitude: 77°55'04.70"E Note: The project site layout plan is appended in Annexure B

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Fig 3.2 Map showing the Project Site Location on District map.

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3.3 BASIS OF SELECTING THE SITE

The efficient functioning of any industry mainly depends on the availability of its basic requirements viz. raw materials, fuel, power, water, manpower etc. The industry is established in Malur Industrial Area, Kolar and Bangalore. The choice of the land confers several advantages, which are summarized below.

1. The site is well connected by roadways. 2. Water will be supplied from water tankers. 3. Power will be supplied from BESCOM. 4. No incidence of cyclones, earthquake, floods or landslides in the region.

3.4 SIZE/MAGNITUDE OF OPERATION The industry “M/s Somu Organo-Chem Pvt. Ltd.,” is a small scale industrial unit with a total

capital investment of the Expansion project is Rs. 4.34 Crores. The total production capacity

proposed is 4, 42,905 kg/month

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3.5 PRODUCTS MANUFACTURED M/s. Somu Organo-Chem Pvt. Ltd. now envisages expansion of its existing industry with

addition of new products to its process line.

The products (specialty chemicals) that are proposed to be manufactured in the expansion project are given in Table no-3.1

Table 3.1 shows present & proposed Products to be manufactured

SI. No. Fine & Specialty chemicals

Production capacity (Kg/month)

Production Capacity (Kg/annum)

1 Benzalkonium chloride 1,00,000 12,00,000

2 1,3 Cyclohexanedione 75,000 9,00,000

3 Ore flotation reagent 2,00,000 24,00,000

4 4-Hydroxy carbazole 2,000 24,000

5 2/4 Methylcyclohexanol 5,000 60,000

6 2,4 Thiazolidinedione 10,000 1,20,000

7 3,3,5 Trimethylcyclohexanol 20,000 2,40,000

Total(A) 4,12,000 49,44,000

Sl. No. Specialty fine Chemicals, bulk drugs, cosmetic and pharma ingredients

No. Of batches

Production capacity (kg/month)

1 4-n Hexylresorcinol 5 250

2 4-n Butylresorcinol 3 150

3 EthylhexylTriazone 7 1000

4 Iscotrizinol 0.5 50

5 PiroctoneOlamine 15 1500

6 Tetrahydrocurcumin 2 125

7 Tetrahydropiperine 2 125

8 1,4-Cyclohexanedione and acetal 10 1000

9 1,4-Cyclohexanediol 5 500

10 (S)-1-Phenyl-1,2,3,4-

Tetrahydroisoquinoline

20 1000

11 3-Quinuclidinone hydrochloride 1 100

12 R-(-)-3-Quinuclidinol 1 50

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13 Ethyl isonipecotate 25 2,500

14 1,2,3,9-Tetrahydro-9-methyl-4(H)-

carbazol-4-one

5 500

15 4-(2,3-epoxypropoxy)carbazole 3 500

16 4-Methoxyethylphenol and Metoprolol 16 1,000

17 Mebeverine Amine 5 1,000

18 2-(2-Ethoxyphenoxy)ethylbromide 0.1 10

19 R-1-(-Methoxyphenyl-N-(R)-1-

phenylethyl)propan-2-amine

hydrochloride

0.3 15

20 R,R-2-methoxy-5-[2-(1-phenylethylamino)-

propyl] benzenesulfonamide

0.38 15

21 R-(-)-5-(2-Aminopropyl)-2-methoxy-

benzenesulfonamide and Tamsulosin

0.75 15

22 4-Methylcyclohexanone 25 2,000

23 Trans-4-Methylcyclohexyl amine 10 500

24 Tris(Hydroxymethyl)aminomethane 5 500

25 Trans-4-aminocyclohexanol 50 5,000

26 Tranexamic acid 10 500

27 Benzethonium chloride 4 1,000

28 Cinnamyl alcohol 50 5,000

29 (R)-(-)-3-Carbamoylmethyl-5-

Methylhexanoic Acid and Pregablin

50 5,000

TOTAL 30,905

The total production capacity is A+B= 4, 12,000 + 30,905=4, 42,905 Kg/month. Or 5,314,860 Kg/annum

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LIST OF PRODUCTS WITH BATCH CYCLE TIME

Sl.No

PRODUCTS No of batches BATCH SIZE (Kg)

BATCH CYCLE TIME

(Days)

PRODUCTION CAPACITY

(Kg/month) 1 4-n Hexylresorcinol 5 50 4 250

2 4-n Butylresorcinol 3 50 4 150

3 EthylhexylTriazone 7 150 4 1000

4 Iscotrizinol 0.5 100 5 50

5 PiroctoneOlamine 15 100 3 1500

6 Tetrahydrocurcumin 2 60 4 125

7 Tetrahydropiperine 2 60 4 125

8 1,4-Cyclohexanedione and acetal 10 100 3 1000

9 1,4-Cyclohexanediol 5 100 3 500

10 (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline

20 50 4 1000

11 3-Quinuclidinone hydrochloride 1 75 7 100

12 R-(-)-3-Quinuclidinol 1 50 4 50

13 Ethyl isonipecotate 25 100 4 2,500

14 1,2,3,9-Tetrahydro-9-methyl-4(H)-carbazol-4-one

5 100 3 500

15 4-(2,3-epoxypropoxy)carbazole 3 150 2 500

16 4-(2-Methoxyethyl)phenol and Metoprolol

16 60 4 1,000

17 Mebeverine Amine 5 200 6 1,000

18 2-(2-Ethoxyphenoxy)ethylbromide 0.1 100 4 10

19 (R)-1-(4-Methoxyphenyl)-N-(R)-1-Phenylethyl)Propan-2-Amine Hydrochloride

0.3 50 4 15

20 R,R-2-methoxy-5-[2-(1-phenylethylamino)-propyl] benzenesulfonamide

0.38 40 8 15

21 R-(-)-5-(2-Aminopropyl)-2-methoxy-benzenesulfonamide and Tamsulosin

0.75 20 10 15

22 4-Methylcyclohexanone 25 80 1 2,000

23 Trans-4-Methylcyclohexyl amine 10 50 3 500

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24 Tris(Hydroxymethyl)aminomethane

5 100 3 500

25 Trans-4-aminocyclohexanol 50 100 2 5,000

26 Tranexamic acid 10 50 4 500

27 Benzethonium chloride 4 250 5 1,000

28 Cinnamyl alcohol 50 100 1 5,000

29 (R)-(-)-3-(Carbamoylmethyl)-5-

methylhexanoic Acid and Pregablin

50 100 4 5,000

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3.5.1 Manufacturing Process Description

3.5.2 Manufacturing process Details of each product

1. PRODUCT NAME : 4-n-HEXYL RESORCINOL : CAS NO : 136-77-6

Mol. Formula : C12H18O2

Mol. Wt. : 194.27

IUPAC Name : 4-Hexyl-1,3-benzene diol,1,3-dihydroxy phenyl hexane.

Structure :

Brief Process:

Resorcinol condensed with Caproic acid in the presence of zinc catalyst gives to 4-hexanoyl

resorcinol . Hydrogenation of hexanoyl resorcinol in the presence of Raney Nickel gives to 4-N

Hexyl Resorcinol.

Route of Synthesis:

Stage-I

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Stage-II

Brief Process:

Resorcinol condensed with Caproic acid in the presence of zinc catalyst gives to 4-hexanoyl

resorcinol . Hydrogenation of hexanoyl resorcinol in the presence of Raney Nickel gives to 4-N

Hexyl Resorcinol.

Application :

Used as a skin whitening agent in cosmetics and also as a anti-dandruff agent in shampoo.

Process Flow Chart

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2. PRODUCT: 4-n-BUTYL RESORCINOL CAS NO : 18979-61-8 Mol. Formula : C10H14O2

Mol. Wt : 166.22

IUPAC Name : 4-Butyl-1,3-benzene diol,3,4-dihydroxy-N-Butyl benzene Structure :

Brief Process:

Resorcinol condensed with butyric acid in the presence of zinc catalyst gives to 4-butyroyl

resorcinol . Hydrogenation of butyroyl resorcinol in the presence of Raney Nickel gives to 4-N

Butyl Resorcinol.

Route of Synthesis:

Stage-I

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Stage-II

Application :

Used as a skin whitening agent in cosmetics and also as a anti-dandruff agent in shampoo .

Process Flow Chart

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3. Ethyl Hexyl Triazone

CAS NO : 88122-99-0 Mol. Formula : C48H66N6O6

Mol. Wt : 823.07

IUPAC Name : 2-ethylhexyl 4-[[4,6-bis[[4-(2-ethylhexoxycarbonyl)phenyl]amino]-1,3,5-triazin-2- yl]amino]benzoate Structure : BRIEF PROCESS : Stage-I PNBA (P-Nitrobenzoic acid) is esterified with 2-Ethylhexanol in presence of catalytic quantity of Sulfuric acid to get PN2EHB (Para nitro 2-ethyl hexyl benzoate). The Sulfuric acid is neutralized with Soda ash and the Unreacted PNBA is extracted with aqueous Soda ash solution which on neutralization gives recovery PNBA. Stage-II

PN2HB is reduced to PA2EHB (Para amino 2-ethyl hexyl benzoate) in presence of Pd/C-H2 in methanol. Pd/C is filtered and reused. Methanol distilled and sent for column distillation. To the residue Hexane is added to expel the product and centrifuged. Stage-III

PA2EHB is reacted with Cyanuric chloride in Xylene to get Etone. To the reaction mass water is added and PH is adjusted with ammonia. Aqueous layer seperated and sent for

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evaporation. The Xylene layer taken for Xylene distillation (recovery). To residue Acetonitrile is added and charcolised – cooled and filtered. Route of Synthesis:

Stage – I

Stage – II

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Stage – III

Application It is used as an UV-B absorbing agent in sunscreen creams, lotions and sun oils.

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Process flow chart

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4. ISOCOTRIZINOL CAS NO : 154702-15-5 Mol. Formula : C44H59N7O5

Mol. Wt : 765.98

IUPAC Name : Benzoicacid,4,4'-[[6-[[4-[[(1,1dimethylethyl)amino]carbonyl]phenyl]amino]- 1,3,5-triazine-2,4-diyl]diimino]bis-,1,1'-bis(2-ethylhexyl) ester STRUCTURE : BRIEF PROCESS : Stage-I : p -Nitrobenzoic acid is reacted with Thionyl Chloride in the presence of Dimethylformamide and Toluene solvent media to get Stage-1 Compound. Stage-II : Stage-1 Compound on treatment with tert-Butylamine in presence of Triethylamine using Toluene as solvent medium to form Stage-2 Intermediate. Stage-III : Stage-2 Intermediate on hydrogenation with Hydrogen in presence of Palladium Carbon catalyst in Methanol and Toluene solvent media gives Stage-3 Compound. Stage-IV : Stage-3 Compound on reaction with Cyanuric Chloride in presence of Potassium Carbonate using Acetonitrile as solvent medium to get Stage-4 Intermediate.

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Stage-V : Stage-4 Intermediate reacts with 2-Ethylhexyl 4-Aminobenzoate in presence of Ammonia in Toluene and Hexane solvent media to obtain the title compound. Route of Synthesis:

Stage – I

Stage – II

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Stage – III

Stage –IV

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Stage – V

Application Iscotrizinol is a superior active providing UVB and UVA photoprotection of skin with proven synergies with many sunscreen activities.

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Process flow chart

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5. PIROCTONE OLAMINE: PRODUCT : PiroctoneOlamine CAS NO. : 68890-66-4 MOl.Formula : C14H23NO2 · C2H7NO Mol.Wt. 298.42 g/mol IUPAC Name : 1-Hydroxy-4-methyl-6-(2, 4, 4-trimethylpentyl) pyridin-2(1H)-one compound with 2-aminoethanol (1:1) Structure: BRIEF PROCESS : Stage-I: Esterification of 3, 3’DMAA with Methanol in the presence of con Sulphuric acid gives to Methyl ester of 3, 3’DMAA Stage-II: Further condensation of methyl ester of 3.3’DMAA with Isononanoyl chloride catalysed by Anhydrous Aluminium Chloride gives to Isononayl derivatives of 3,3’ DMAA. Stage-III: Isononanyl derivative of 3,3’ DMAA undergoes cyclisation in the presence of Sodium methoxide in methanol at 5 – 10 Deg C followed by neutralization with acetic acid gives to Crude 4-Methyl-6-(2,4,4-trimetylpentyl)-2-Pyrone. Further 4-Methyl-6-(2,4,4-trimetylpentyl)-2-Pyrone is purified by High Vacuum distillation. Stage-IV: The above purified 4-Methyl-6-(2,4,4-trimethylpentyl)-2-pyrone condensed with hydroxylamine hydrochloride in the presence of sodium Carbonate at 60 – 65 ˚C gives to 1-Hydroxy-4-Methyl-6-(2,4,4-trimethylpentyl)-2-pyridone further treated with monoethanolamineUnder chilled condition 8 – 10 ˚C results in formation of Crude Piroctoneolamine.

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The above obtained crude product is recrystallised from ethyl acetate ROUTE OF SYNTHESIS

Stage – I

Stage – II

Stage – III

Stage – IV

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Application:

PiroctoneOlamine is a broad-spectrum microbiocide/microbiostat, may be used in

formulating antidabdruff shampoo, hair keep and hair care, soap, etc.

Process flow chart

.

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6. PRODUCT : TETRAHYDROCURCUMINOIDS CAS NO : 36062-04-1 Mol.Formula : C21H26O6

Mol.Wt : 372.2 IUPAC Name : (1,7-Bis (4-hydroxy-3-methoxyphenyl) heptane-3,5-dione Structure :

Brief Process: Curcuminoids obtained from Turmeric is hydrogenated by using Palladium on Carbon as a Catalyst gives to TetrahydroCurcuminoids. Filtered the Product and dried under Vacuum at 45-50 deg C till LOD reaches Less than 0.5% then packed in Clean Polythene Bag. Route of Synthesis

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Application: Used as a skin conditioning and skin whitening agent. Process flow chart

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7. PRODUCT : TETRAHYDROPIPERINE

CAS NO : 23434-88-0 Mol.Formula : C17H23NO3

Mol.Wt : 289.36 IUPAC Name : 1- [5- (1, 3-Benzodioxol-5 yl)-1-oxo-pentanoyl]-Piperidine Structure :

Brief Process:

Piperine obtained from Pepper is hydrogenated by using Palladium on Carbon as a Catalyst

gives to Tetrahydropiperine.

Filtered the Product and dried under Vacuum at 45-50 deg C till LOD reaches Less than 0.5%

then packed in Clean Polythene Bag.

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Route of Synthesis

Application:

Used as an enhancers of nutrient and bio availability enhancer for medicines.

Process flow chart

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8. PRODUCT : 1,4-CYCLOHEXANEDIONE AND ACETAL CAS NO. : 637-88-7 MOl.Formula : C6H8O2 Mol.Wt. : 112.12 IUPAC Name : 1,4-Cyclohexanedione, Cyclohexane-1,4-dione Structure :

BRIEF PROCESS : Condensation of DMS in presence of Sodium methoxide followed by neutralization with Aquoussulphuric acid gives to Dicarbmethoxycarboxy -1,4-CHD . Decarboxylation of Dicarbmethoxycarboxy -1,4-CHD results in Cyclohexane-1,4-dione. Route of Synthesis

Stage - I

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Stage – II

Application:

Intermediate for FROVATRPAN and used as a building block in the synthesis of more complex

molecules and liquid crystals

Process flow chart

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9. PRODUCT : 1,4-CYCLOHEXANEDIOL CAS NO. : 556-48-9 MOl.Formula : C6H12O2 Mol.Wt. : 116.16 IUPAC Name : 1,4-Cyclohexanediol, Hexahydrohydroquinone Structure :

BRIEF PROCESS : Hydroquinone in IPA undergoes hydrogenation in presence of Raney Nickel catalyst to give 1,4-Cyclohexanediol. Route of Synthesis

Application It is used in the production of polyester fibers and organic intermediates etc.Acts as an anti-inflammatory agent. It is a diol monomer. Used in skin care products.

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Process flow chart

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10. (S)-1-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE CAS NO. : 118864-75-8 MOl.Formula : C15H15N Mol.Wt. : 209.29 IUPAC Name : (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Structure :

Brief Process: Stage-I: N-(2-Phenylethyl)benzamide: 2-Phenylethylamine condensed with benzoyl chloride in methylene dichloride as a solvent to give N-(2-Phenylethyl)benzamide. Stage-II: 1-Phenyl-1,2-dihydroisoquinoline: N-(2-Phenylethyl)benzamide reacts with phospphrous pentoxide and phosphorous oxychloride in the presence of sodium hydroxide by using toluene as a solvent to give 1-Phenyl-1,2-dihydroisoquinoline. Stage-III: 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline: 1-Phenyl-1,2-dihydroisoquinoline undergoes reduction with sodium borohydride in methanol as a solvent to give 1-Phenyl-1,2,3,4-tetrahydroisoquinoline. Stage-IV (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline tartarate: 1-Phenyl-1,2,3,4-tetrahydroisoquinoline undergoes resolution with D-(-)-tartaric acid in IPA as a solvent to give (S)-1-Phenyl-1,2,3,4-Tetrahydrohydroisoquinoline tartarate salt. Stage-V (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline: 1-Phenyl-1,2,3,4-tetrahydroisoquinoline tartarate undergoes base hydrolysis in MDC as a solvent to give (S)-1-Phenyl-1,2,3,4-Tetrahydrohydroisoquinoline.

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Route of Synthesis

Stage – I

Stage – II

Stage – III

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Stage-IV

Stage-V

Application

A Key Intermediate for the Anti muscarinic Agent Solifenacin

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Process flow chart

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11. 3-QUINUCLIDINONE HYDROCHLORIDE CAS NO. : 1193-65-3 MOl.Formula : C7H12ClNO Mol.Wt. : 161.63 IUPAC Name : 1-Azabicyclo[2.2.2]octan-3-one hydrochloride Structure :

Brief Process: Stage-I: Ethyl 1-(2-methoxy-2- oxoethyl)piperidine-4-carboxylate:Ehtyl piperidine-4-carboxylate is condensed with methyl chloroacetate in presence of sodium carbonate followed by hydrogenation to give ethyl 1-(2-methoxy-2- oxoethyl)piperidine-4-carboxylate. Stage-II: 3-Quinuclidinone Hydrochloride:Ethyl 1-(2-methoxy-2- oxoethyl)piperidine-4-carboxylate undergoes Dieckmann reaction in presence of potassium tertbutoxide followed by hydrolysis and decarboxylation gave title compound 3-quinuclidinone hydrochloride.

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Route of synthesis Stage - I

Stage – II

Application used in the synthesis of cevimeline, a thiolating agent.

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Process flow chart

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12. R-(-)-3-QUINUCLIDINOL CAS NO. : 25333-42-0 MOl.Formula : C7H13NO Mol.Wt. : 127.18 IUPAC Name : (3R)-1-Azabicyclo[2.2.2]octan-3-ol Structure :

Brief Process: 3-Quinuclidinone in isopropyl alcohol undergoes hydrogenation in presence of 5% Ruthenium on carbon to give R-(-)-3-Quinuclidinol. Route of Synthesis

Application Hypotensive. Synthon for preparation of cholinergic receptor ligands and anesthetics.

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13. ETHYL ISONIPECOTATE CAS NO. : 1126-09-6 MOl.Formula : C8H15NO2 Mol.Wt. : 157.21 IUPAC Name : Ethyl 4-piperidinecarboxylate Structure :

Brief Process: Ethyl isonicotinate undergoes hydrogenation in the presence of 10% palladium on carbon gives ethyl isonipecotate Route of Synthesis

Application Reactant for synthesis of:

• SMN protein modulators • β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition • Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone

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• RhoA inhibitors for cardiovascular disease therapy • Saccharin derived Mannich bases as antimicrobials and antioxidants

Process flow chart

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14. 1,2,3,9-TETRAHYDRO-9-METHYL-4(H)-CARBAZOL-4-ONE CAS NO. : 27387-31-1 MOl.Formula : C13H13NO Mol.Wt. : 199.25 IUPAC Name : 1,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one Structure :

Brief Process: 1,2,3,9-Tetrahydro-9-methyl-4(H)-carbazol-4-one: 1,2,3,9-Tetrahydro-4(H)-carbazol-4-one in methylene dichloride reacts with dimethylformamide in presence of tetrabutyl ammonium bromide to give 1,2,3,9-Tetrahydro-9-methyl-4(H)-carbazol-4-one. Route of synthesis

Application Intermediate of Ondansetron

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Process flow chart

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15. 4-(2,3-EPOXYPROPOXY)-9H-CARBAZOLE CAS NO. : 51997-51-4 MOl.Formula : C15H13NO2 Mol.Wt. : 239.27 IUPAC Name : 4-(2-Oxiranylmethoxy)-9H-carbazole; 4-Glycidyloxycarbazole Structure :

Brief Process: 4-(2,3-Epoxypropoxy)-9H-carbazole: 4-Hydroxycarbazole will be reacted with Epichlorohydrin& sodium hydroxide in presence of DMSO & D M Water. Further addition of DM water to Reacttion Mass will give the desired product. The crude product will be washed with water. Crude product will be purified by using activated charcoal, ethyl acetate and methanol to give pure product. Route of Synthesis

Application Intermediate for Carvedilol

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Process flow chart

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16. 4-(2-METHOXYETHYL)PHENOL AND METOPROLOL CAS NO. : 56718-71-9 MOl.Formula : C9H12O2 Mol.Wt. : 152.19 IUPAC Name : 4-(2-Methoxyethyl)phenol Structure :

Brief Process: Stage-I: 2-Chloro-1-(4-hydroxyphenyl)ethanone:Aluminium chloride was added to phenol in ethylene dichloride and heated to reflux. Then chlroacetyl chloride is added, heated and then cooled. Then the material is separated out and the material is purified methanol. Stage-II: 2-Methoxy-1-(4-hydroxyphenyl)ethanone: A solution of sodium methoxide and 2-chloro-1-(4-hydroxyphenyl)ethanone was stirred and concentrated. The material was treated with hydrochloric acid and and extracted with chloroform. The chloroform layer was washed with water and chloroform was distilled out to give 2-Methoxy-1-(4-hydroxyphenyl)ethanone. Stage-III: 4-(2-Methoxyethyl)phenol: 2-Methoxy-1-(4-hydroxyphenyl)ethanone was hydrogenated in methanol in the presence of 10% palladium on carbon. The material was filtered and the filtered solution was distilled out to give 4-(2-Methoxyethyl)phenol.

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Route of Synthesis Stage – I

Stage – II

Stage – III

Application used to manufacture Metoprolol

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Process Flow Chart

(Reused / Regeneration)

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17. MEBEVERINE AMINE CAS NO : 3625-06-7

Mol. Formula : C25H35NO5

Mol. Wt. : 492.55

IUPAC Name : (RS)-4-(ethyl[1-(4-methoxyphenyl)propan-2-yl]amino)butyl 3,4-dimethoxybenzoate Structure :

Brief Process: Stage-I: 3,4-Dimethoxybenzoic acid -4-bromobutyl ester: 3,4-Dimethoxybenzoic acid reacts with sodium methoxide in Methanol as a solvent to give sodium 3,4-dimethoxybenzoate. Sodium 3,4-dimethoxybenzoate undergoes esterification with 1,chloro-4-bromobutane to give 3,4-dimethoxybezoic acid-4-bromobutyl ester. Stage-II Ethyl-[2-(4-methoxyphenyl)-1-methylethyl]amine: 1-(4-methoxyphenyl)-propan-2-one undergoes reductive amino ethylation with hydrogen gas in presence of 10%Pd/C in Methanol as a solvent to give Ethyl-1-[2[(4-methoxyphenyl)-1-methylethyl]amine. Stage-III Mebeverine Amine: 3,4-Dimethoxybezoic acid-4-bromobutyl ester and Ethyl-1-[2[(4-methoxyphenyl)-1-methylethyl]amine reacts with sodium carbonate in presence of MIBK as a solvent to give Mebeverine amine.

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Route of Synthesis Stage – I

Stage – II

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Stage – III

Application

Antispasmodic.

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Process Flow Chart

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18. 2-(2-ETHOXYPHENOXY)ETHYL BROMIDE CAS NO. : 3259-03-8 MOl.Formula : C10H13BrO2 Mol.Wt. : 245.11 IUPAC Name : 1-(2-Bromoethoxy)-2-ethoxy-benzene Structure :

Brief Process: 2-Ethoxyphenol is reacted with Ethylene dibromide under phase transfer catalyst in toluene, 2-(2-Ethoxyphenoxy)ethyl bromide which on recrystalistion in IPA, pure product is formed. Route of Synthesis

Application It is used as an intermediate in Tamsulosin

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Process Flow Chart

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19. (R)-1-(4-METHOXYPHENYL)-N-(R)-1-PHENYLETHYL)PROPAN-2-AMINE HYDROCHLORIDE CAS NO : 50505-66-3

Mol. Formula : C18H24ClNO

Mol. Wt. : 305.84

IUPAC Name : (αR)-4-Methoxy-α-methyl-N-[(1R)-1-phenylethyl]benzeneethanamine Hydrochloride [R-(R*,R*)]-4-Methoxy-α-methyl-N-(1-phenylethyl)benzeneethanamine Hydrochloride Structure :

.HCl Brief Process: The reductocondensation of 4-Methoxyphenylacetone with R-(+)-phenylethylamine gives regioselectively the secondary amine as the HCl salt. Route of Synthesis

Application Used as an intermediate in Tamsulosin

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Process Flow Chart

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20. (R,R)-2-METHOXY-5-[2-(1-PHENYLETHYLAMINO)PROPYL]BENZENESULFONAMIDE Mol. Formula : C18H24N2O3S

Mol. Wt. : 348.46

Structure :

Brief Process: Stage-I The reductocondensation of 4-Methoxyphenylacetone with R-(+)-phenylethylamine gives regioselectively the secondary amine as the HCl salt. Stage-II The secondary amine.HCl undergoes sulfonation with chlorosulfonic acid and treatment with NH4OH yields (R,R)-2-methoxy-5-[2-(1-phenylethylamino)propyl]benzenesulfonamide . Route of Synthesis STAGE-I

+ Methanol, Toluene, Acetone, .HCl 4-Methoxy R(+)-Phenyl Hydrogen, IPA.HCl , Catalyst 5-(2R-aminopropyl)-N-methylbenzyl- Phenyl acetone ethylamine 2-methoxybenzene.hydrochloride STAGE-II

.HClChlorosulfonic acid, Thionyl chloride 5-(2R-aminopropyl)-N-methylbenzyl Ammonia, Chloroform, 2-methoxybenzene.hydrochloride Application Used as an intermediate in Tamsulosin Process Flow Chart

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21. R(-)-5-(2-AMINOPROPYL)-2-METHOXY-BENZENESULFONAMIDE AND TAMSULOSIN CAS NO : 112101-81-2

Mol. Formula : C10H16O3N2S

Mol. Wt. : 244.31

IUPAC Name : 5-[(2R)-2-Aminopropyl]-2-methoxy-benzenesulfonamide, (R)-5-(2-Aminopropyl)-2-methoxy-benzenesulfonamide, Structure :

Brief Process: Stage-I The reductocondensation of 4-Methoxyphenylacetone with R-(+)-phenylethylamine gives regioselectively the secondary amine as the HCl salt. Stage-II The secondary amine.HCl undergoes sulfonation with chlorosulfonic acid and treatment with NH4OH yields (R,R)-2-methoxy-5-[2-(1-phenylethylamino)propyl]benzenesulfonamide . Stage-III (R,R)-2-methoxy-5-[2-(1-phenylethylamino)propyl]benzenesulfonamide in methanol undergoes dehydrogenation with hydrogen gas in presence of 10% palladium on carbon to give R(-)-5-(2-Aminopropyl)-2-methoxy-benzenesulfonamide. Route of Synthesis STAGE-I

+ Methanol, Toluene, Acetone, .HCl 4-Methoxy R(+)-Phenyl Hydrogen, IPA.HCl , Catalyst 5-(2R-aminopropyl)-N-methylbenzyl-

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Phenyl acetone ethylamine 2-methoxybenzene.hydrochloride STAGE-II & III

.HClChlorosulfonic acid, Thionyl chloride 5-(2R-aminopropyl)-N-methylbenzyl Ammonia, Chloroform, Methanol R(-)5-(2-aminopropyl)2-methoxy- 2-methoxybenzene.hydrochloride Hydrogen gas, 10% Pd/C benzenesulfonamide Application Used as an intermediate in Tamsulosin Process Flow Chart

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22. 4-METHYLCYCLOHEXANONE

CAS NO : 589-92-4

Mol. Formula : C7H12O

Mol. Wt. : 112.17

IUPAC Name : 4-Methylcyclohexanone

Structure :

Brief Process: 4-Methylcyclohexanone: 4-Methylcyclohexanol reacted with sodium hypochlorite and acetic acid followed by distillation to give 4-Methylcyclohexanone. Route of Synthesis

Application

Used a spermidine synthase inhibitor Process flow chart

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23. TRANS-4-METHYLCYCLOHEXYL AMINE

CAS NO : 2523-55-9

Mol. Formula : C7H15N

Mol. Wt. : 113.20

IUPAC Name : trans-4-Methylcyclohexan-1-amine

Structure :

Brief Process: Stage-I: 4-Methylcyclohexanone: 4-Methylcyclohexanol reacted with sodium hypochlorite and acetic acid to give 4-Methylcyclohexanone. Stage-II: 4-Methylcyclohexanone oxime :4-Methylcyclohexanone reacted with hydroxylamine hydrochloride in presence of caustic soda lye to give 4-Methylcyclohexanone oxime. Stage-III: 4-Methylcyclohexyl amine: 4-Methylcyclohexanone oxime in methanol undergoes hydrogenation with hydrogen gas in presence of Raney Nickel catalyst. The reaction mass is filtered and methanol is completely distilled out under vacuum to give 4-Methyl amine. Stage-IV Trans-4-Methylcyclohexylamine hydrochloride: To a solution of4-Methylcyclohexylamine, methanolic hydrochloric acid is added to give 4-Methylcyclohexylamine hydrochloride, which is then purified in acetone to give trans-4-Methylcyclohexylamine hydrochloride. Stage-V Trans-4-Methylcyclohexylamine:

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To a solution oftrans-4-Methylcyclohexylamine hydrochloride, methanolic sodium hydroxide is added to give trans-4-Methylcyclohexylamine, which is then purified to give trans-4-Methylcyclohexylamine. Route of Synthesis

Stage – I

Stage – II

Stage – III

Stage – IV

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Stage – V

Application Used a spermidine synthase inhibitor Process Flow chart

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24. TRIS(HYDROXYMETHYL)AMINOMETHANE

CAS NO : 77-86-1

Mol. Formula : C4H11NO3

Mol. Wt. : 121.14

IUPAC Name : 2-Amino-2-hydroxymethyl-propane-1,3-diol Structure :

Brief Process

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Tris(hydroxymethyl)aminomethane may best be prepared by the exhaustive hydroxymethylation of nitromethane with the subsequent reduction of the nitro group. Route of Synthesis

Stage – I

Stage – II

Application

It is a zwitterionic biological buffer with a useful buffering range of 7.2-9.0, often used as a buffering agent in biological and biochemical research. Also known applied in bio-pharma manufacturing process. Process Flow Chart

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25. TRANS-4-AMINOCYCLOHEXANOL

CAS NO : 27489-62-9

Mol. Formula : C6H13NO

Mol. Wt. : 115.18

IUPAC Name : Trans-4-Hydroxycyclohexylamine

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Structure :

Brief Process: Stage-I Paracetamol undergoes hydrogenation in presence of Raney Nickel catalyst in IPA to give 4-Acetamidocyclohexanol. Stage-II 4-Acetamidocyclohexanol undergoes hydrolysis with sodium hydroxide to give 4-aminocyclohexanol. 4-aminocyclohexanol is refluxed in toluene and cooled to get trans-4-aminocyclohexanol. Route of Synthesis

Stage – I

Stage – II

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Application It is used as raw material in organic synthesis and is an important intermediate in the synthesis

of drugs such as Ambroxol hydrochloride.

Process Flow Chart

26. TRANEXAMIC ACID

CAS NO : 1197-18-8

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Mol. Formula : C8H15NO2

Mol. Wt. : 157.21

IUPAC Name : Trans-4-(Aminomethyl)cyclohexanecarboxylic acid Structure :

Route of Synthesis

Stage – I

Stage – II

Stage – III

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Process flow chart

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27. BENZETHONIUM CHLORIDE

CAS NO : 121-54-0

Mol. Formula : C27H42ClNO2

Mol. Wt. : 448.08

IUPAC Name : Benzyldimethyl(2-{2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl) azanium chloride Structure :

Brief Process: Stage-I p-octylphenol is reacted 2-chloroethanol in the presence of sodium hydroxide in toluene to get p-ter-octylphenoxyethanol. Stage-II p-octylphenoxyethanol is reacted 2-dimethylaminoethylchloride in the presence of sodium hydroxide in toluene to get p-tert-octylphenoxyethoxyethyldimethylamine. Stage-III p-tert-octylphenoxyethoxyethyldimethylamine is refluxed with benzylchloride in toluene to get benzethonium chloride.

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Route of Synthesis Stage -I

Stage –II

Stage – III

Application Used as a topical anti-infective agent. Benzethonium chloride is an ingredient in medicaments,

deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing

and pharmaceutical industries, in surgery, and also as a preservative.

Process flow chart

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28. CINNAMYL ALCOHOL

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CAS NO : 104-54-1

Mol. Formula : C9H10O

Mol. Wt. : 134.18

IUPAC Name : 3-Phenyl-2-propen-1ol

Structure :

Brief Process: Cinnamaldehyde in methanol is reacted with sodium borohydridetogivecinnamyl alcohol. After distilling methanol, cinnamyl alcohol is also distilled out. Route of Synthesis

Application Used as a fragrance ingredient and as a flavoring agent Process flow chart

29. (R)-(-)-3-CARBAMOYMETHYL-5-METHYLHEXANOIC ACID AND PREGABLIN

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CAS NO : 181289-33-8

Mol. Formula : C9H17NO3

Mol. Wt. : 187.24

IUPAC Name : (R)-3-(2-AMINO-2-OXOETHYL)-5-METHYLHEXANOIC ACID

Structure :

Brief Process: Stage-I Route of Synthesis Application Used as a fragrance ingredient and as a flavoring agent

Process flow chart

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3.6 RAW MATERIALS The raw materials required and proposed for the production of specialty chemicals are appended in the table 3.2 below. Raw materials as listed will be procured as per the production requirement.

Table -3.2 Raw Materials Requirement for production of specialty chemicals S.No

.

Product Raw materials Quantity Required Solvents

required

after

recycling

kg/annum

Solid/L

iquid

Packing

Kg/

Batch

Kg/

Month

Kg/

Annum

1 4-n-Hexyl

resorcinol

Resorcinol 100 500 6000 - Solid 25kg/

bag

Caproic acid 200 1000 12000 - Liquid 170kg/

drum

Zinc catalyst 10 50 600 - Solid 25kg/

drum

Raney Nickel

catalyst

10 50 600 - Solid 10kg/

drum

Hexane 350 1750 21000 2100 Liquid 140kg/

drum

Methanol 500 2500 30000 3000 Liquid 160kg/

drum

Nitrogen gas

cylinders

4 20 240 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

5 25 300 - Gas 7cu.m./

cylinder

Water for

process

600 3000 36000 -

Water for

washing

500 2500 30000 -

2 4-n-Butyl

resorcinol

Resorcinol 111 333 3996 - Solid 25kg/

bag

Butyric acid 194 582 6984 - Liquid 170kg/

drum

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Zinc catalyst 11 33 396 - Solid 25kg/

drum

Raney Nickel

catalyst

10 30 360 - Solid 10kg/

drum

Hexane 350 1050 12600 1260 Liquid 140kg/

drum

Methanol 500 1500 18000 1800 Liquid 160kg/

drum

Nitrogen gas

cylinders

4 12 144 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

5 15 180 - Gas 7cu.m./

cylinder

Water for

process

600 1800 21600 -

Water for

washing

500 1500 18000 -

3 Ethyl

hexyltriazo

ne

p-Nitrobenzoic

acid

100 667 8004 - Solid 25kg/

bag

2-Ethylhexanol 95 634 7608 - Liquid 170kg/

drum

Sulfuric acid 15 100 1200 - Liquid 50kg/

drum

Sodium

carbonate

30 200 2400 - Solid 50kg/

bag

Toluene 450 3002 36024 3602 Liquid 170kg/

drum

Nitrogen gas

cylinders

4 27 324 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 60 720 - Gas 7cu.m./

cylinder

10% Palladium

on carbon

catalyst

5 33.5 402 - Solid 10kg/

drum

Methanol 600 4002 48024 4002 Liquid 160kg/

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drum

Ammonia

solution

6 40 480 - Liquid 190kg/

drum

Perchloroethylen

e

1000 6670 800040 6403 Liquid 250kg/

drum

Cyanuric chloride 35 233.5 2802 - Solid 50kg/

drum

Xylene 400 2668 32016 3202 Liquid 180kg/

drum

Acetonitrile 600 4002 48024 1802 Liquid 150kg/

drum

Activated carbon 5 33.5 402 - Solid 25kg/

bag

Hyflo 5 33.5 402 - Solid 21.2kg/

bag

Water for

process

1600 10672 128064 -

Water for

washing

900 6003 72036 -

4 Isocotrizino

l

p-Nitrobenzoic

acid

48 24 288 - Solid 25kg/ba

g

Thionyl chloride 20 10 120 - Liquid 200kg/d

rum

Toluene 900 450 5400 840 Liquid 170kg/d

rum

Caustic soda lye 30 15 180 - Liquid Tanker

t-Butylamine 29 14.5 174 - Liquid 140kg/d

rum

Triethylamine 33 16.5 198 - Liquid 140kg/d

rum

Potassium

carbonate

38 19 228 - Solid 50kg/ba

g

Methanol 500 250 3000 300 Liquid 160kg/

drum

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10% Palladium

on catalyst

3 1.5 18 - Solid 10kg/

drum

Nitrogen gas

cylinders

6 3 36 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

8 4 48 - Gas 7cu.m./

cylinder

Cyanuric chloride 45 22.5 270 - Solid 50kg/

drum

Acetonitrile 255 112.5 1350 150 Liquid 150kg/

drum

Hexane 500 250 3000 300 Liquid 140kg/

drum

Ammonia

solution

41 20.5 246 - Liquid 190kg/

drum

Activated carbon 5 2.5 30 - Solid 25kg/

bag

Hyflo 5 2.5 30 - Solid 21.2kg/

bag

Water for

process

900 450 5400 -

Water for

washing

500 250 3000 -

5 PiroctoneO

lamine

3,3-

Dimethylacrylic

acid

125 1875 22500 - Solid 25kg/dr

um

Methanol 770 11550 138600 12600 Liquid 160kg/d

rum

Sulphuric acid 25 375 4500 - Liquid 50kg/

drum

Sodium

Carbonate

30 450 5400 - Solid 50kg/

bag

Toluene 450 6750 81000 8100 Liquid 160kg/d

rum

Isononanoyl 250 3750 45000 - Liquid 250kg/d

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chloride rum

Ethylene

dichloride

800 12000 144000 14400 Liquid 160kg/d

rum

Aluminium

chloride

500 75000 900000 - Solid 25kg/

drum

Caustic soda lye 400 6000 72000 - Liquid Tanker

Sodium

methoxide

125 1875 22500 - Solid 25kg/ba

g

Acetic acid 125 1875 22500 - Liquid 160kg/d

rum

Hydroxylamine

hydrochloride

190 2850 34200 - Solid 25kg/

drum

Ethylacetate 1250 18750 225000 22500 Liquid 160kg/d

rum

Monoethanol

amine

12.5 187.5 2250 - Liquid 210kg/d

rum

Water for

process

1500 22500 270000 -

Water for

washing

500 7500 90000 -

6 Tetrahydro

curcuminoi

ds

Curcumin 100 167 2004 - Solid 25kg/

drum

Acetone 900 1875 22500 2246 Liquid 160kg/dr

um

10% Pd/C

Catalyst

5 10.5 126 - Solid 25kg/

drum

Nitrogen gas

cylinders

5 10.5 126 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 19 228 - Gas 7cu.m./

cylinder

Isopropyl alcohol 450 936 11232 1123 Liquid 170kg/dr

um

Activated carbon 8 17 204 - Solid 25kg/

bag

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Hyflo 5 10.5 126 - Solid 21.2kg/

bag

Water for

washing

500 1042 12504 -

7 Tetrahydro

piperine

Piperine 100 167 2004 - Solid 25kg/

drum

Acetone 900 1875 22500 2246 Liquid 160kg/dr

um

10% Pd/C

Catalyst

5 10.5 126 - Solid 25kg/

drum

Nitrogen gas

cylinders

5 10.5 126 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

9 19 228 - Gas 7cu.m./

cylinder

Isopropyl alcohol 450 936 11232 1123 Liquid 170kg/dr

um

Activated carbon 8 17 204 - Solid 25kg/

bag

Hyflo 5 10.5 126 - Solid 21.2kg/

bag

Water for

washing

500 1042 12504 -

8 1,4-

Cyclohexan

edione and

acetal

Dimethylsuccinat

e

660 6600 79200 - Liquid 200kg/dr

um

Sodium

methoxide

260 2600 31200 - Solid 25kg/bag

Toluene 1000 10000 120000 10800 Liquid 170kg/dr

um

Methanol 250 2500 30000 3600 Liquid 160kg/dr

um

Sulphuric acid 500 5000 60000 - Liquid 50kg/dru

m

Ethyl acetate 700 7000 84000 8400 Liquid 185kg/dr

um

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Activated carbon 6 60 720 - Solid 25kg/

bag

Hyflo 5 50 600 - Solid 21.2kg/

bag

Water for

process

5600 56000 672000 -

Water for

washing

500 5000 60000 -

9 1,4-

Cyclohexan

ediol

Hydroquinone 110 550 6600 - Solid 25kg/bag

Isopropyl alcohol 700 3500 42000 4200 Liquid 165kg/dr

um

Ethyl acetate 500 2500 30000 3000 Liquid 185kg/dr

um

Raney Nickel

catalyst

10 50 600 - Solid 10kg/dru

m

Nitrogen gas

cylinders

6 30 360 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

19 95 1140 - Gas 7cu.m./

cylinder

Water for

washing

500 2500 30000 -

10 (S)-1-

Phenyl-

1,2,3,4-

Tetrahydro

isoquinolin

e

Phenylethylamin

e

140 2800 33600 - Liquid 190kg/dr

um

Benzoyl chloride 100 2000 24000 - Liquid 250kg/dr

um

Sodium

hydroxide flakes

88 1760 21120 - Solid 50kg/bag

Methylene

dichloride

400 8000 96000 9600 Liquid 250kg/dr

um

10 (S)-1-

Phenyl-

1,2,3,4-

Tetrahydro

isoquinolin

e

Phosphorus

pentoxide

108 2160 25920 - Solid 50kg/dru

m

Phosphorous

oxychloride

259 5180 62160 - Liquid 50kg/dru

m

Toluene 300 6000 72000 7200 Liquid

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Caustic soda lye 420 8400 100800 - Liquid Tanker

Ethyl acetate 700 14000 168000 19200 Liquid 185kg/dr

um

Methanol 600 12000 144000 16800 Liquid 160kg/dr

um

Sodium

borohydride

20 400 4800 - Solid 40kg/dru

m

Nitrogen gas

cylinders

3 60 720 - Gas 7cu.m./

cylinder

Isopropyl alcohol 1000 20000 240000 24000 Liquid 165kg/dr

um

D-(-)-tartaric acid 82 1640 19680 - Solid 50kg/bag

Water for

process

1200 24000 288000 -

Water for

washing

800 16000 192000 -

11 3-

Quinuclidin

one

hydrochlori

de

Ethyl

isonicotinate

157 210 2520 - Liquid 160kg/dr

um

Methyl

chloroacetate

108 145 1740 - Liquid 50kg/dru

m

Sodium

carbonate

90 121 2544 - Solid 50kg/dru

m

Methanol 900 1206 14472 1437 Liquid 160kg/dr

um

10% Palladium

on carbon

catalyst

5 7 84 - Solid 10kg/dru

m

Potassiu-t-

butoxide

112 150 1800 - Solid 50kg/dru

m

Butanol 600 804 9648 958 Liquid 160kg/dr

um

Sulfuric acid 50 67 804 - Liquid 50kg/dru

m

11 3- Caustic soda lye 100 134 1368 - Liquid Tanker

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Quinuclidin

one

hydrochlori

de

Acetone 50 67 804 80 Liquid 160kg/dr

um

Water for

process

900 1200 14400 -

Water for

washing

600 800 9600 -

12 R-(-)-3-

Quinuclidin

ol

3-Quinuclidinone 100 100 1200 - Solid 25kg/dru

m

Methanol 600 600 7200 720 Liquid 160kg/dr

um

Ethyl acetate 400 400 4800 480 Liquid 185kg/dr

um

5% Ruthenium

on carbon

catalyst

4 4 48 - Solid 10kg/dru

m

Nitrogen gas

cylinders

6 6 72 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

6 6 72 - Gas 7cu.m./

cylinder

Methylene

dichloride

200 200 2400 - Liquid 250kg/

drum

Water for

washing

1000 1000 12000 -

13 Ethyl

isonipecota

te

Ethyl

isonicotinate

125 3125 37500 - Liquid 160kg/

drum

Methanol 600 15000 180000 18000 Liquid 160kg/

drum

10% Palladium

on carbon

4 100 1200 - Solid 10kg/

drum

Nitrogen gas

cylinder

6 150 1800 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

14 350 4200 - Gas 7cu.m./

cylinder

Methylene 200 5000 60000 6000 Liquid 250kg/

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dichloride drum

Water for

washing

700 17500 210000 -

14 1,2,39-

Tetrahydro

-9-methyl-

4(H)-

carbazol-4-

one

1,2,3,9-

Tetrahydro-4(H)-

carbazole

125 625 7500 - Solid 25kg/

drum

Methylene

dichloride

700 3500 42000 4200 Liquid 250kg/

drum

Dimethylformami

de

45 225 2700 - Liquid 200kg/

drum

Caustic soda lye 66 330 3960 - Liquid Tanker

Tetrabutylammo

nium bromide

1 5 60 - Solid 25kg/

drum

Water for

process

100 500 6000 -

Water for

washing

500 2500 30000

15 4-(2,3-

Epoxyprop

oxy)-9H-

Carbazole

4-

Hydroxycarbazol

e

200 668 8016 - Solid 25kg/

drum

Epichlorohydrin 236 708 8496 - Liquid 220kg/

drum

Isopropyl alcohol 700 2338 28056 2797 Liquid 165kg/

drum

Caustic soda lye 102 341 4080 - Liquid Tanker

Water for

process

900 3000 36000 -

Water for

washing

500 1667 20004 -

16 4-(2- Phenol 94 1567 18804 - Liquid 200kg/

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 140

Methoxyet

hyl)phenol

and

Metoprolol

drum

Chloroacetyl

chloride

214 3568 42816 - Liquid 220kg/

drum

Aluminium

chloride

267 4451 53412 - Solid 25kg/

drum

Caustic soda lye 300 5001 60012 - Liquid Tanker

Ethylene

dichloride

350 5835 70020 8401 Liquid 220kg/

drum

Hydrochloric acid 400 6668 80016 - Liquid 220kg/

drum

Methanol 1210 20171 242052 24005 Liquid 220kg/

drum

Sodium

methoxide

110 1834 22008 - Solid 25kg/

drum

10% Palladium

on carbon

4 67 804 - Solid 10kg/

drum

Nitrogen gas

cylinder

3 50 600 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

5 84 1008 - Gas 7cu.m./

cylinder

Water for

processing

600 10002 120024 -

Water for

washing

800 13336 160032 -

17 Mebeverin

e amine

3,4-

Dimethoxybenzoi

c acid

200 1000 12000 - Solid 25kg/

drum

Methanol 2300 11500 138000 13800 Liquid 160kg/

drum

Sodium

methoxide

60 300 3600 - Solid 25kg/

drum

1-chloro-4-

bromobutane

800 4000 48000 - Liquid 250kg/

drum

Toluene 1100 5500 66000 7800 Liquid 170kg/

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 141

drum

4-Methoxyphenyl

acetone

175 875 10500 - Liquid 200kg/

drum

70%Monoethyl

amine

140 700 8412 - Liquid 160kg/

drum

10% Palladium

on carbon

catalyst

5 25 300 - Solid 10kg/

drum

Nitrogen gas

cylinder

6 30 360 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinder

7 35 420 - Gas 7cu.m./

cylinder

Methyl

isobutylketone

200 1000 12000 - Liquid 165kg/

drum

Anhydrous

sodium sulfate

30 150 1800 - Solid 50kg/

drum

Water for

process

950 4750 57000 -

Water for

washing

800 4000 48000 -

18 2-(2-

Ethoxyphe

noxy)ethyl

bromide

2-Ethoxyphenol 89 9 108 - Liquid 200kg/

drum

Ethylene

dibromide

180 18 216 - Liquid 250kg/

drum

Caustic soda lye 130 13 156 - Liquid Tanker

Tetrabutyl

ammonium

bromide

10 1 12 - Solid 25kg/

drum

Isopropyl alcohol 200 20 240 24 Liquid 165kg/

drum

Sodium chloride 30 3 36 - Solid 50kg/ bag

Water for

process

1000 100 1200 -

Water for 500 50 600 -

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 142

washing

19 R-1-(-

Methoxyph

enyl-N-(R)-

1-

phenylethy

l)propan-2-

amine

hydrochlori

de

4-

Methoxyphenyla

cetone

80 24 288 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 15 180 - Liquid 50kg/

drum

Toluene 540 162 1944 144 Liquid 170kg/

drum

Methanol 2000 600 7200 540 Liquid 160kg/

drum

HCl in isopropyl

alcohol

70 21 252 - Liquid 30kg/

drum

Acetone 1400 420 5040 540 Liquid 160kg/

drum

Raney Nickel

catalyst

25 7.5 90 - Solid 10kg/

drum

Nitrogen gas

cylinders

9 3 36 - Gas 7cu.m./

cylinder

19 R-1-(-

Methoxyph

enyl-N-(R)-

1-

phenylethy

l)propan-2-

amine

Hydrogen gas

cylinders

7 2 24 - Gas 7cu.m./

cylinder

Water for

washing

800 240 2880 -

20 (R,R)-2-

Methoxy-5-

[2-(1-

phenylethy

lamino)pro

pyl]benzen

e

ssulfonami

de

4-

Methoxyphenyla

cetone

80 30 360 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 19 228 - Liquid 200kg/

drum

Toluene 540 202.5 2430 182 Liquid 170kg/

drum

Methanol 2000 750 9000 684 Liquid 160kg/

drum

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 143

HCl in isopropyl

alcohol

70 26 312 - Liquid 30kg/

drum

Acetone 1400 525 6300 684 Liquid 160kg/

drum

Raney Nickel

catalyst

25 9.5 114 - Solid 10kg/

drum

Nitrogen gas

cylinders

9 5 60 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

7 6 72 - Gas 7cu.m./

cylinder

Chlorosulfonic

acid

82 31 372 - Liquid 200kg/

drum

Thionyl chloride 41 15.5 186 - Liquid 220kg/

drum

Chlorofrom 1200 450 5400 456 Liquid 220kg/

drum

Ammonia

solution

440 165 1980 - Liquid 220kg/

drum

Caustic soda lye 100 37.5 450 - Liquid 220kg/

drum

Water for

process

260 97.5 1170 -

Water for

washing

1300 487.5 5850 -

21 R-(-)-5-(2-

Aminoprop

yl)-2-

methoxy-

benzene

sulfonamid

e and

Tamsulosin

4-

Methoxyphenyla

cetone

80 60 720 - Liquid 200kg/

drum

R-(+)-

Phenylethylamin

e

50 38 456 - Liquid 200kg/

drum

Toluene 540 405 4860 360 Liquid 170kg/

drum

Methanol 2000 1500 18000 2250 Liquid 160kg/

drum

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Pre-Feasibility Report 144

HCl in isopropyl

alcohol

70 52.5 630 - Liquid 30kg/

drum

Acetone 1400 1050 12600 1350 Liquid 160kg/

drum

Raney Nickel

catalyst

25 19 228 - Solid 10kg/

drum

Nitrogen gas

cylinders

14 11 132 - Gas 7cu.m./

cylinder

Hydrogen gas

cylinders

15 11 132 - Gas 7cu.m./

cylinder

Chlorosulfonic

acid

82 61.5 738 - Liquid 200kg/

drum

Thionyl chloride 41 31 372 - Liquid 200kg/

drum

Chlorofrom 1200 900 10800 900 Liquid 250kg/

drum

Ammonia

solution

440 330 3960 - Liquid 190kg/

drum

Caustic soda lye 100 75 900 - Liquid Tanker

10% Palladium

on carbon

catalyst

15 11 132 - Solid 10kg/

drum

Water for

process

260 195 2340 -

Water for

washing

1500 1125 13500 -

22 4-

Methylcycl

ohexanone

4-

Methylcyclohexa

nol

110 2750 33000 - Liquid 170kg/

drum

Sodium

hypochlorite

solution

744 18600 223200 - Liquid 200kg/

drum

Acetic acid 91 2275 27300 - Liquid 200kg/

drum

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Pre-Feasibility Report 145

Water for

washing

500 12500 150000 - Liquid 220kg/

drum

23 Trans-4-

Methylcycl

ohexyl

amine

4-

Methylcyclohexa

nol

110 1100 13200 - Liquid 170kg/d

rum

Sodium

hypochlorite

solution

744 7440 89280 - Liquid 200kg/d

rum

Acetic acid 91 910 10920 - Liquid 200kg/d

rum

Hydroxylamine

hydrochloride

80 800 9600 - Solid 25kg/

HDPE

drums

Caustic soda lye 165 1650 19800 - Liquid Tanker

Isopropyl alcohol 400 4000 48000 4800 Liquid 170kg/d

rum

Raney Nickel

catalyst

8 80 960 - Solid 10kg/

HDPE

drum

Nitrogen gas

cylinders

4 40 480 - Gas 7cu.m/c

ylinder

Hydrogen gas

cylinders

6 60 720 - Gas 7cu.m/c

ylinder

Hydrochloric acid 80 80 960 - Liquid Tanker

Acetone 450 4500 54000 6000 Liquid 160kg/d

rum

n-Butanol 1000 10000 120000 12000 Liquid 160kg/d

rum

Water for

washing

1000 10000 120000 -

24 Tris(Hydrox

ymethyl)a

minometha

ne

Nitromethane 110 550 6600 - Liquid 225kg/dr

um

Paraformaldehyd

e

185 925 11100 - Solid 25kg/bag

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M/S Somu Organo-Chem Pvt. Ltd.,

Pre-Feasibility Report 146

Methanol 1400 7000 84000 8400 Liquid 160kg/dr

um

Potassium

hydroxide

0.30 1.5 18 - Solid 50kg/bag

Raney Nickel

catalyst

20 100 1200 - Solid 10kg/bag

Nitrogen gas

cylinders

6 30 360 - Gas 7cu.m/cyl

inder

Hydrogen gas

cylinders

10 50 600 - Gas 7cu.m/cyl

inder

Activated carbon 5 25 300 - Solid 25kg/ bag

Hyflo 5 25 300 - Solid 21.2kg/

bag

Water for

process

300 1500 18000 -

Water for

washing

600 3000 36000 -

25 Trans-4-

Aminocyclo

hexanol

Paracetamol 200 10000 120000 - Solid 50kg/ bag

Isopropyl alcohol 1200 60000 720000 72000 Liquid 160kg/dr

um

Raney Nickel

catalyst

12 600 7200 - Solid 10kg/ bag

Nitrogen gas

cylinder

7 350 4200 - Gas 7cu.m/cyl

inder

Hydrogen gas

cylinder

19 950 11400 - Gas 7cu.m/cyl

inder

Caustic soda lye 128 6400 76800 - Liquid 160kg/dr

um

Toluene 1200 60000 720000 72000 Liquid 160kg/dr

um

Activated carbon 5 250 3000 - Solid 25kg/ bag

25 Trans-4-

aminocyclo

Hyflo 5 250 3000 - Solid 21.2kg/

bag

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Pre-Feasibility Report 147

hexanol Water for

process

200 10000 120000 -

Water for

washing

600 30000 360000 -

26 Tranexamic

acid

p-Cyanobenzoic

acid

100 1000 12000 - Solid 25kg/dr

um

Raney Nickel

catalyst

10 100 1200 - Solid 10kg/dr

um

Methanol 900 9000 108000 10800 Liquid 160kg/d

rum

Nitrogen gas

cylinders

14 140 1680 - Gas 7cu.m/

cylinder

Hydrogen gas

cylinders

28 280 3360 - Gas 7cu.m/

cylinder

Ammonia

solution

100 1000 12000 - Liquid 200kg/d

rum

5% Ruthenium

on carbon

catalyst

5 50 600 - Solid 10kg/dr

um

Hydrochloric acid 80 800 9600 - Liquid Tanker

Sulphuric acid 5 50 600 - Liquid 50kg/dr

um

Caustic soda lye 50 500 6000 - Liquid Tanker

Activated carbon 4 40 480 - Solid 25kg/

bag

Hyflo 4 40 480 - Solid 21.2kg/

bag

Water for

process

1200 12000 144000 -

Water for

washing

900 9000 108000 -

27 Benzethoni

um

chloride

p-t-Octylphenol 206 824 9888 - Solid 25kg

/bag

Caustic soda lye 276 1104 13248 - Liquid Tanker

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Pre-Feasibility Report 148

Benzyltrimethyla

mmonium

chloride

20 80 960 - Solid 25kg/

drum

Toluene 3000 12000 144000 14400 Liquid 170kg/d

rum

2-Chloroethanol 121 484 5808 - Liquid 200kg/d

rum

Benzylchloride 91 364 4368 - Liquid 230kg/d

rum

Dimethylaminoet

hylchloridehydro

chloride

216 864 10368 - Solid 25kg/

bag

Water for

process

1000 4000 48000 -

Water for

washing

1000 4000 48000 -

28 Cinnamylal

chol

Cinnamaldehyde 111 5550 66600 - Liquid 200kg/d

rum

Methanol 666 33300 399600 39600 Liquid 160kg/d

rum

Sodiumborohydri

de

33 1650 19800 - Solid 30kg/

drum

Hydrochloric acid 100 5000 60000 - Liquid Tanker

Water for

washing

500 25000 300000 -

29 R-(-

)Carbamoyl

methyl-5-

methylhex

anoic acid

and

Pregablin

Isovareldehyde 121 6050 72600 - Liquid 160kg/d

rum

Ethyl

cyanoacetate

160 8000 96000 - Liquid 200kg/d

rum

Di-n-propylamine 10 500 6000 - Liquid 140kg/d

rum

Diethyl malonate 217 10850 130200 - Liquid 200kg/d

rum

Hexane 900 45000 540000 60000 Liquid 140kg/d

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Pre-Feasibility Report 149

rum

Urea 80 4000 48000 - Solid 25kg/ba

g

Caustic soda lye 93 4650 55800 - Liquid Tanker

Chloroform 1000 50000 600000 60000 Liquid 250kg/d

rum

R-(+)-

Phenylethylamin

e

70 3500 42000 - Liquid 200kg/d

rum

Hydrochlroic acid 73 3650 43800 - Liquid Tanker

Water for

process

500 25000 300000 -

Water for

washing

500 25000 300000 -

Note: The Material Safety Data Sheet of Raw Materials (MSDS) is appended in Annexure C 3.6.1 STORAGE FACILITY FOR RAW MATERIALS AND PRODUCTS Adequate storage facilities with the required area is earmarked for the raw materials, specialty chemicals and packing material. Racking system/stackers, etc. are provided as per requirement. Corrosive chemicals are proposed to be kept in separate area with ventilation system. Closed storage rooms are provided for finished products as well as raw materials, as applicable. They are stored in polyethylene bags & drums, HMHDPE drums and metal coated drums (all in sealed condition) as per requirement.

Table 3.3:- Details of Storage Facilities

Sl. No. Storage Facility for Facility

1 Raw Materials Warehouse

2 Products Bonded finished goods store

3 Industrial Effluent The industrial effluents are stored in two collection tank of about 80,000 L capacity and sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal

4 Hazardous Waste In organic Process residue and organic waste from process is collected in HDPE Bags and sent to PCB authorized Processers for land filling

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Pre-Feasibility Report 150

Spent carbon is collected in HDPE Bags and sent to PCB authorized Processers for land filling Used Containers after detoxification will be sold to authorized agents.

3.6.2 MACHINERY & EQUIPMENT DETAILS The detailed list of machinery& equipments in the industry are appended in the tables 3.4 below Table 3.4a List of Equipments

Sl. no. Equipments No.s

1. Glass Lined Reactor 250L 1 2. Glass Lined Reactor 1KL 2

3. Glass Lined Reactor 2KL 2

4. Glass Lined Reactor 3KL 2

5. Glass Lined Reactor 4KL 1

6. S.S. Reactor 250L 1

7. S.S. Reactor 500L 1

8. S.S. reactor 5KL 1

9. S.S. Reactor 2KL 1

10. Vacuum Tray Dryer 1

11. Fluid Bed Dryer 1

12. Multimill 1

13. Blender 1

14. Sifter 1

15. Centrifuge 1

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Pre-Feasibility Report 151

Table 3.4bList of Utilities

3.7 RESOURCE OPTIMIZATION/RECYCLING AND RE-USE ENVISAGED IN THE PROJECT 3.7.1 Solvent Recovery & Re-Use Various solvents are proposed to be used during the manufacturing process. The solvents

proposed to be recovered and recycled during the process of recovering the solvent of such

product are detailed in table 3.5 below.

Sl. no.

Utilities Nos.

1. Steam Boiler 2ton/hr. (Chimney height – 30.5m)

1

2. Brine Chiller 20TR/minus 20deg. 1

3. Cooling tower 250TR 1

4. Cooling Tower 1

5. Softener Water Plant 1

6. Water ring vacuum pump 2

7. Steam ejector 1

8. Water pump 10

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Pre-Feasibility Report 152

3.7.2 SOLVENT RECOVERY SYSTEM 1. Solvent to be recovered is transferred in to a closed, Jacketed, Vertical, cylindrical and

agitated reactor.

2. Control measure for reactor, are Temperature, Pressure and speed of agitator.

3. Reactor Jacket has all the utility connections.

4. Vapor line connected to primary condenser, where in the cooling water is circulated.

(Cooling water has the multi pass facility to achieve better heat transfer and counter flow).

5. The system has an additional facility of reflux system.

6. The condensed liquid from primary condenser will flow to secondary condenser by gravity,

where in chilled water is circulated for further sub cooling of recovered solvent.

7. The vent of primary condenser is connected again to the same secondary condenser with

necessary control valve system. In total secondary condenser acts like sub cooler and as

well as vent cooler.

8. The measure control for both condenser and sub cooler are pressure and temperature both

on tube side and on shell side.

9. The sub cooled solvent then flows and collects in 2 receivers, where in further cooling is

made by circulating the chilled brine. The measure control for both receiver is the

temperature and pressure in shell as well as in Jacket.

10. The vent is always from the receiver to the wet scrubber or the vacuum pump.

3.8 HAZARDOUS RAW MATERIALS USED IN THE MANUFACTURING PROCESS The following raw materials used during the process of production of specialty chemicals are hazardous in nature according to Manufacture, Storage and Import of Hazardous Chemical (Amendment) Rules, 19th January 2000, Schedule I, Part II in the table 3.6

Table: 3.5 Hazardous raw materials

Hazardous raw material Sl. No. as per Manufacture, Storage and Import of Hazardous

Chemical (Amendment) Rules, 19th January, 2000, Schedule I,

Part II

Acetic acid 2

Acetone 4

Aluminium chloride 23

Ammonia solution 31

Benzoyl chloride 65

Benzyl chloride 67

Chlorosulfonic acid 136

Epichlorohydrin 239

Ethyl hexanol-2 254

Ethylene dibromide 263

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Pre-Feasibility Report 153

Hexane 306

Hydrogen 314

Hydroquinone 319

Isopropyl alcohol 334

Methanol 377

Methyl isobutylketone 388

Nitrogen 429

Perchloroethylene 479

Phenol 481

Phosphorous oxychloride 504

Phosphorous pentaoxide 505

Potassium hydroxide 522

Sodium hydroxide 571

Sulphuric acid 591

Thionyl chloride 620

Triethylamine 652

3.8.1 Hazardous waste generation and its management during the manufacturing process

The hazardous wastes generated during the production of specialty fine chemicals, bulk drugs,

cosmetic and pharma ingredients are stored at hazardous waste storage area and sent to

authorized reprocessers. The quantities of hazardous waste generated from various processes

are shown in the Table- 3.7.

Note: The Product Hazop Study is appended in Annexure D

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Pre-Feasibility Report 154

1. Spent Carbon

Table: 3.6 Quantity of spent Carbon waste generated from manufacturing process

Si .No. Product Spent Carbon generated Kg/Batch

1 Ethyl hexyltriazone 10

2 Isocotrizinol 10

4 Tetrahydrocurcuminoids 13

5 Tetrahydropiperine 13

6 1,4-Cyclohexanedione and acetal 11

7 Tris(Hydroxymethyl)aminomethane 10

8 Trans-4-Aminocyclohexanol 10

9 Tranexamic acid 8

3.8.2 Hazardous Waste Quantity and Disposal Details

Table 3.7a) Hazardous Waste Quantity and Disposal Details (EXISTING)

Sl.No Hazardous waste generated

Quantity Method of Handling

1 a)Used oil b)Vacuum oil

0.15KL/A 0.35KL/A

Shall be collected in leak-proof containers and disposed only to KSPCB registered authorized re-processors provided the oil meets the standards as per Schedule-5 Part-A of the Rules

2 a)Oil soaked cotton waste b)Oil filters

0.2MT/A 5Nos./A

Shall be stored in a secured manner and handed over to KSPCB authorized incinerator/co-processing in cement kiln.

3 Discarded containers Chemical contaminated paper & plastic bags

3600Nos./A 21MT/A

Store in a secured manner and handed over to KSPCB authorized recycler after wash only

4 ETP sludge 0.4MT/A Stored in secure manner and handed over to KSPCB authorized to TDSF

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Pre-Feasibility Report 155

Table 3.7b) Hazardous Waste Quantity and Disposal Details (PROPOSED)

Sl. No. Source Quantity of hazardous waste

generated Kg/month

Disposal Options

1. Spent Carbon 867 Disposed through Cement industries for co incinerations

2. Waste oil from DG 30 liters Disposed through authorized recyclers

3. Spent Solvent 1,44,858 Disposed through KSPCB authorized dealers

4. HDPE/Discarded containers 1,965Nos. Disposed through authorized recyclers

5. Chemical contaminated paper & plastic bags

1,340kg/month Disposed through authorized recyclers

6. Distillation residue sludge 500kg/month Stored in a secure manner and handed over to TSDF

3.9 DOMESTIC SOLID WASTE RE-USE

The total quantity of domestic wastes generated for 75 workers is about19 kg/day of which 60% (12Kg/day) is organic and 40% (7Kg/day) is inorganic waste, which will be segregated at source, collected in bins and composted. The composted waste will be used as manure for landscape development.

3.10 WATER, ENERGY/POWER REQUIREMENT & SOURCE

3.10.1 Water

The water demand is met from water tanker supply. The requirement of water for the unit is appended in section 3.11.1 later in the report.

3.10.2 Power

The total power requirement of the industry is 459hp or 342 kVA. Further diesel generator of 250 kVA capacity is installed to serve as an alternative source of power supply to this unit.

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Pre-Feasibility Report 156

3.11 WASTES GENERATED & SCHEME FOR WASTE MANAGEMENT/DISPOSAL

3.11.1 Water demand and wastewater/effluent discharge for the proposed expansion

Source of water supply: Water Tanker Supply Total number of employees: 75 people

The total quantity of water required for the industry is about 111KLD. The break-up of the consumption of water is as presented below.

Table 3.8 Water consumption and discharge Water consumed for

Consumption

LPD

Recirculation

/RecycleLPD

Loss/Consumption/Evaporation /Daily Make Up Water Etc. LPD

Discharge

LPD

(a) Domestic 3750 3,750 3,375

(b) Landscape development 5,000 5,000 -

(c) Industrial purpose 1,02,000 74,000 30,450

Softener 43,000 15,000 14,750

c. Process water from Softener

d. Boiler water from Softener

7,631 or say 8,000

35,000

Recirculation water = 35,000-7000 (5250 Evaporation loss +1750 Blow down=28000

7,631 or say 8,000

Evaporation loss + blowdown loss(5250 +1750)=7000

11,000

1,750

(blow down)

Softener rejects 2000

5 Washings 14,000 14,000 14,000

6 Cooling tower 35,000

Evaporation loss + bleed off =(34,300+700)=35,000

700(bleed off)

7 Scrubber(1+1new) 1,000 1,000 1,000

8 Water for steam jet ejector

9,000 9,000 -

Total 1,10,750 28,000 82,750 33,825

LPD = L/day; KLD = kilo liter/day. Startup water requirement for industrial purpose is 110750 LPD or say 111KLD. Daily

requirement after recycling from boiler Condensate: 110750-28000 = 82750 LPD or say 82KLD

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Proposed Water Balance Chart

Domestic wastewater

3375LPD

* Process effluent =11,000 LPD, DM rejects=2,000 LPD

30,450LPD or 31KLD will be sent to CETP

Septic tank Soak pit

Scrubber 10000LPD

500 LPD

Boiler makeup water 7,000LPD = (35,000 -28,000=7,000(1,750+5,250)

Cooling tower 35000LPD

Washing =14000

LPD

DM water Plant 20000 LPD

Process consumption

8000LPD

LANDSCAPING 5000 LPD

WATER TANKERS SUPPLY

Cooling Tower bleed off 700LPD

INITIAL WATER CONSUMPTION- 111KLD

DOMESTIC WATER DEMAND 3750 LPD

Scrubber effluent

10000 LPD

INDUSTRIAL WATER DEMAND- 111KLD Start up requirement Daily requirement after recycling from boiler Condensate: 110750-28000 = 82000 LPD or say82KLD

Boiler blow down1750LPD

Condensate

28000LPD

DAILY WATER CONSUMPTION =82KLD

Evaporation Loss= 5,250 LPD

Washing effluent

14000LPD

Evaporation Loss

34,300LPD

Steam jet ejector 9000

Lost 9000LPD

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3.11.2 Total water requirement and waste water discharge details after expansion

The total water requirement for the industry after the proposed expansion is about 130KLD and

The total waste water discharge is about 50KLD.

Table 3.9: Sewage/effluent treatment and discharge

Sewage/effluent generated from

Treatment units provided Final disposal point

(a) Domestic Treated in Septic tank Disposed to Soak pit

(b) Industrial Two Collection tanks of 40,000 KL capacity each are provided.

Industrial effluent is sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

Description Existing (EC obtained) Proposed Total water

requirement after

expansion

(KLD)

Water requirement

(KLD)

Industrial 16 Industrial 102 118

Domestic 1.5 Domestic 3.7 5.2

Landscaping 1.0 Landscaping 5.0 6.0

Total 18.5 Total 110.5 Total=129

Waste water

Generation

(KLD)

Industrial 15 Industrial 31 46

Domestic 1.2 Domestic 3.0 3.2

Total 16.2 Total 34 Total=49.20

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3.12 Product wise water consumption and discharge

Table 3.10: Product-wise water consumption for process and effluent discharge

Sl.NO

Products Water consumptio

n (L/batch)

Effluent discharge(L

/batch)

No. of batches /month

Total water consumption

(L/month)

Total effluent

discharge (L/month)

1 4-n Hexylresorcinol 600 860 5 3000 4300

2 4-n Butylresorcinol 600 1848 3 1800 2598

3 EthylhexylTriazone 1600 0 7 11200 760.38

4 Iscotrizinol 900 945 0.5 450 591.5

5 PiroctoneOlamine 1500 1941 15 22500 54037.5

6 Tetrahydrocurcumin ----- 0 2 ---- 83.2

7 Tetrahydropiperine ----- 0 2 ---- 83.2

8 1,4-Cyclohexanedione and acetal

5600 5000 10 56000 59150

9 1,4-Cyclohexanediol ---- 0 5 ---- 80

10 (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline

1200 2909 20 24000 76120

11 3-Quinuclidinone hydrochloride

900 950 1 900 1860.67

12 R-(-)-3-Quinuclidinol ----- 0 1 --- 50

13 Ethyl isonipecotate ------ 0 25 --- 625

14 1,2,3,9-Tetrahydro-9-methyl-4(H)-carbazol-4-

one

100 140 5 500 1200

15 4-(2,3-epoxypropoxy)carbazole

900 1020 3 2700 4289.04

16 4-Methoxyethylphenol and Metoprolol

600 1020 16 9600 32089.75

17 Mebeverine Amine 950 992 5 4750 11230

18 2-(2-Ethoxyphenoxy)ethylbrom

ide

1000 1129 0.1 100 135.8

19 R-1-(-Methoxyphenyl-N-(R)-1-phenylethyl)propan-

2-amine hydrochloride

------ 0 0.3 ---- 24

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20 R,R-2-methoxy-5-[2-(1-phenylethylamino)-

propyl] benzenesulfonamide

260 640 0.38 98.8 388.74

21 R-(-)-5-(2-Aminopropyl)-2-methoxy-

benzenesulfonamide and Tamsulosin

260 640 0.75 195 782.25

22 4-Methylcyclohexanone ---- 670 25 --- 21175

23 Trans-4-Methylcyclohexyl amine

----- 809 10 --- 12260

24 Tris(Hydroxymethyl)aminomethane

300 300 5 1500 2725

25 Trans-4-aminocyclohexanol

200 300 50 10000 21400

26 Tranexamic acid 1200 1373 10 12000 14850

27 Benzethonium chloride 1000 1196.5 4 4000 7044

28 Cinnamyl alcohol ---- 0 50 ---- 3650

29 (R)-(-)-3-

Carbamoylmethyl-5-

Methylhexanoic Acid and

Pregablin

500 620 50 25000 59700

TOTAL 190293.8 393283

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3.13 Product wise Effluent generation Table 3.11: Product-wise effluent generation for process

SI.No.

Product Effluent Quantity Generated No. of

Kg/Batch Kg/month Kg/Annum batches

1 4-n-Hexyl resorcinol

Inorganic waste 10 50 600 5

Organic waste 234 1170 14040

Water 616 3080 36960

Total 860 4300 51600

2 4-n-Butyl resorcinol

Inorganic waste 11 33 396 3

Organic waste 239 717 8604

Water 616 1848 22176

Total 866 2598 31176

3 Ethyl hexyltriazone Inorganic waste 45 300.15 3601.8 7

Organic waste 69 460.23 5522.76

Water 0 0 0

Total 114 760.38 9124.56

4 Isocotrizinol Inorganic waste 99 49.5 594 0.5

Organic waste 139 69.5 834

Water 945 472.5 5670

Total 1183 591.5 7098

5 PiroctoneOlamine Inorganic waste 785 11775 141300 15

Organic waste 876.5 13147.5 157770

Water 1941 29115 349380

Total 3602.5 54037.5 648450

6 Tetrahydrocurcuminoids

Inorganic waste 0 0 0 2

Organic waste 40 83.2 998.4

Water 0 0 0

Total 40 83.2 998.4

7 Tetrahydropiperine Inorganic waste 0 0 0 2

Organic waste 40 83.2 998.4

Water 0 0 0

Total 40 83.2 998.4

8 1,4-Cyclohexanedione

and acetal

Inorganic waste 683 6830 81960 10

Organic waste 232 2320 27840

Water 5000 50000 600000

Total 5915 59150 709800

9 1,4-Cyclohexanediol Inorganic waste 0 0 0 5

Organic waste 16 80 960

Water 0 0 0

Total 16 80 960

10 (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoli

ne

Inorganic waste 575 11500 138000 20

Organic waste 322 6440 77280

Water 2909 58180 698160

Total 3806 76120 913440

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11 3-Quinuclidinone hydrochloride

Inorganic waste 148 196.84 2362.08 1

Organic waste 301 400.33 4803.96

Water 950 1263.5 15162

Total 1399 1860.67 22328.04

12 R-(-)-3-Quinuclidinol Inorganic waste 0 0 0 1

Organic waste 50 50 600

Water 0 0 0

Total 50 50 600

13 Ethyl isonipecotate Inorganic waste 0 0 0 25

Organic waste 25 625 7500

Water 0 0 0

Total 25 625 7500

14 1,2,39-Tetrahydro-9-methyl-4(H)-

carbazol-4-one

Inorganic waste 30 150 1800 5

Organic waste 70 350 4200

Water 140 700 8400

Total 240 1200 14400

15 4-(2,3-Epoxypropoxy)-9H-

Carbazole

Inorganic waste 198 659.34 7912.08 3

Organic waste 70 233.1 2797.2

Water 1020 3396.6 40759.2

Total 1288 4289.04 51468.48

16 4-(2-Methoxyethyl)pheno

l and Metoprolol

Inorganic waste 652 10868.84 130426.08 16

Organic waste 253 4217.51 50610.12

Water 1020 17003.4 204040.8

Total 1925 32089.75 385077

17 Mebeverine amine Inorganic waste 125 625 7500 5

Organic waste 1129 5645 67740

Water 992 4960 59520

Total 2246 11230 134760

18 2-(2-Ethoxyphenoxy)ethyl

bromide

Inorganic waste 134 13.4 160.8 0.1

Organic waste 95 9.5 114

Water 1129 112.9 1354.8

Total 1358 135.8 1629.8

19 R-1-(-Methoxyphenyl-N-

(R)-1-phenylethyl)propan-

2-amine

Inorganic waste 0 0 0 0.3

Organic waste 80 24 288

Water 0 0 0

Total 80 24 288

20 (R,R)-2-Methoxy-5-[2-(1-

phenylethylamino)propyl]benzene sulfonamide

Inorganic waste 283 107.54 1290.48 0.38

Organic waste 100 38 456

Water 640 243.2 2918.4

Total 1023 388.74 4664.88

21 R-(-)-5-(2- Inorganic waste 283 212.25 2547 0.75

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Aminopropyl)-2-methoxy-benzene sulfonamide and

Tamsulosin

Organic waste 120 90 1080

Water 640 480 5760

Total 1043 782.25 9387

22 4-Methylcyclohexanon

e

Inorganic waste 59 1475 17700 25

Organic waste 142 3550 42600

Water 670 16750 201000

Total 871 21775 261300

23 Trans-4-Methylcyclohexyl

amine

Inorganic waste 153.5 1535 18420 10

Organic waste 263.5 2635 31620

Water 809 8090 97080

Total 1226 12260 147120

24 Tris(Hydroxymethyl)aminomethane

Inorganic waste 0 0 0 5

Organic waste 245 1225 14700

Water 300 1500 18000

Total 545 2725 32700

25 Trans-4-Aminocyclohexanol

Inorganic waste 0 0 0 50

Organic waste 128 6400 76800

Water 300 15000 180000

Total 428 21400 256800

26 Tranexamic acid Inorganic waste 37 370 4440 10

Organic waste 75 750 9000

Water 1373 13730 164760

Total 1485 14850 178200

27 Benzethonium chloride

Inorganic waste 262.5 1050 12600 4

Organic waste 302 1208 14496

Water 1196.5 4786 57432

Total 1761 7044 84528

28 Cinnamylalchol Inorganic waste 63 3150 37800 50

Organic waste 10 500 6000

Water 0 0 0

Total 73 3650 43800

29 R-()Carbamoylmethyl-5-methylhexanoic acid and Pregablin

Inorganic waste 35 1750 21000 50

Organic waste 539 26950 323400

Water 620 31000 372000

Total 1194 59700 716400

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3.14 Waste Water Characteristics

Table 3.12 Waste Water Characteristics

Sl. No

Parameters Results Protocol

1 pH 6.22 IS:3025 (P 11)

2 Oil & grease, mg/L <1.0 IS:3025 (P 39)

3 Total suspended solids, mg/L 180 IS:3025 (P 17)

4 Bio-chemical Oxygen Demand (at 270C for

3 days), mg/L

27,000 IS:3025 (P 44)

5 Total Dissolved Solids, mg/L 2,46,620 IS:3025 (P 16)

6 Total hardness as CaCO3, mg/L 43.5 IS:3025 (P 21)

7 Conductivity, µ omh/cm 3,72,000 APHA

8 Magnesium, as Mg, mg/L 2.4 IS:3025 (P 46)

9 Total chlorides, as Cl, mg/L 91,266 IS:3025 (P 32)

10 Total sulfates, as SO4, mg/L 1.3 IS:3025 (P 24)

11 Silica, as SiO2, mg/L <0.2 IS:3025 (P 35)

12 Iron, as Fe, mg/L 13.7 IS:3025 (P 53)

13 Phenolpthalein alkalinity, as CaCO3, mg/L Nil IS:3025 (P 23)

14 Methylorange alkalinity, as CaCO3, mg/L 16,320 IS:3025 (P23)

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3.15 Air Pollution Sources The major air pollution sources from the industry are DG set and process sections. These sources are provided with stacks of adequate height so as to disperse the emanating flue gases containing SPM, oxides of sulfur and nitrogen without affecting the ground level concentrations and packed column scrubbers are provided to the process sections with adequate stack height as per the regulatory requirements.

The sources of air pollution, type of fuel used, fuel consumption and chimney heights for each of the air pollution sources of the project are indicated in the following table 3.13.

Air Pollution Sources and Control (EXISTING)

Sl No.

Chimney attached to

Minimum chimney height to be provided above ground level

Rate of emiision Nm3/Hr.

Constituents to be controlled in the emission

Tolerance Limits mg/Nm3

Air pollution Control equipment to be installed, in addition to chimney height as per Col.(3)

1. HSD fired Thermic Fluid Heater 2lakh K.Cal/Hr.

13m AGL - SO2 - -

2. Process/Flash drier

5m ARL - Acid mist VOCs

35 Cyclone separator with water jet scrubber

3. 250KVA DG set 5m ARL - SO2 - Acoustic enclosures

4. Attached to Laboratory Area

3m ARL - Acid Mist 50 Scrubber & packed fume extraction system

5. Attached to Neutralizing Tanks (8Nos.)

3m ARL - Acid Mist 50 Scrubber

6. HSD fired Thermic Fluid Heater 2lakh K.Cal/Hr.

13m AGL - SO2 - -

7. Process/Flash drier

5m ARL - Acid mist VOCs

- Cyclone separator with water jet scrubber

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Table-3.13 Air Pollution Sources and Control (PROPOSED)

SI. no.

Stack attached to

Fuel used Fuel consumption

Number of

stacks

Stack/s height

Air pollution control unit

Predicted emissions

1. Process (attached to reactors)

- - 1 5 m ARL Scrubber Acid mist / VOCs

2. Attached to R&D lab

- - 1 5 m ARL Scrubber & packed fume

extraction system

Acid mist

3. Boiler 2T/hr. (proposed)

Wood/Agro waste

300Kg/hr 1 30.5m AGL

Stack SOx, NOx,SPM

The exhaust temperature is nearly ambient and adequate port holes with access platform will be provided as per KSPCB guidelines as under

3.13.1 Scrubbing System Details

Scrubber systems are a diverse group of air pollution control devices that can be used to remove particulates and/or gases from industrial exhaust streams. Traditionally, the term "scrubber" has reference to pollution control devices that used liquid to "scrub" unwanted pollutants from a gas stream.The term is also used to describe systems that inject a dry reagent or slurry into a dirty exhaust stream to "scrub out" acid gases. Scrubbers are one of the primary devices that control gaseous emissions, especially acid gases.

Wet scrubber is a form of pollution control technology in which the polluted gas stream is brought into contact with the scrubbing liquid by spraying it with the liquid, by forcing it through a pool of liquid, or by some other contact method, so as to remove the pollutants.

The design of wet scrubbers or any air pollution control device depends on the industrial process conditions and the nature of the air pollutants involved. Inlet gas characteristics and dust properties (if particles are present) are of primary importance. Scrubbers can be designed to collect particulate matter and/or gaseous pollutants. Wet scrubbers remove dust particles by capturing them in liquid droplets; remove pollutant gases by dissolving or absorbing them into the liquid.

Any droplets that are in the scrubber inlet gas must be separated from the outlet gas stream by means of another device referred to as a mist eliminator or entrainment separator (these terms are interchangeable). Also, the resultant scrubbing liquid must be treated prior to any ultimate discharge or before being reused in the plant.

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There are numerous configurations of scrubbers and scrubbing systems, all designed to provide good contact between the liquid and polluted gas stream.

The process section and vapor adsorption unit are provided with scrubber to scrub the fumes and vapors generated in order to remove such emissions before it is let out into the atmosphere.

A PP with FRP scrubber of size 600 mm dia x 1000 mm overall height with 400 mm packing height and inbuilt sump tank fabricated with 3 mm polypropylene armored externally with 8 mm thick FRP using isophthalic resin and E-glass reinforcement complete with various nozzles, demister pad, spray pipe complete etc.

The scrubber is connected to PP with FRP blower (1 W + 1 SB) of capacity 1500 CMH against 200 mm water column with 2 HP 1440 RPM FLP motor and MS base frame. The scrubber is connected to a PP recirculation pump of capacity 12 CMH against 12 m head.

Flash drier cyclone separator with water jet scrubber unit set-up

Fig 3.4 Water jet scrubber

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3.16 Noise pollution details The major source of noise pollution in the industry is the DG set for which acoustic enclosure is provided. Also ambient noise levels are ensured to be within the ambient standards by inbuilt design of mechanical equipment and building apart from vegetation (tree plantations) along the periphery and at various locations within the industry premises.

3.17 Solid waste details The quantity of solid waste generated from the proposed industry is detailed in the following table 3.14.

Table: 3.14 Solid Waste Generation during the Operation Phase

Details Existing proposed

Total no. of employees 60 75

Assuming per capita solid waste generation rate as 0.25 kg/capita/day

Quantity of solid waste generated 15kg/day 19Kg/day

Organic solid waste : 60 % of the total waste 9kg/day 12kg/day

Inorganic solid waste : 40 % of the total waste 6kg/day 7kg/day

The domestic wastes are segregated at source, collected in bins and handed over to KSSIDC for scientific disposal.

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3.18 SCHEMATIC REPRESENTATIONS OF THE OVERALL FEASIBILITY AND ENVIRONMENTAL ASSESSMENT PROCESS

Fig 3.6: Feasibility & environmental Assessment Process

Significant

Not

Economic

Feasibility study conducted for Newly proposed industry

Statement of intent by proponent

Guidelines for EIA by SEAC/MoEF

Abandon project

Determine the coverage of the EIA - scoping

Describe the environment – baseline study

Describe the project

Identify the impacts

Evaluate the impacts

Mitigation

Preventive measures

Prepare draft EIS

FINAL EIA REPORT

CONSIDER ALL PHASES OF PROJECT –

CONSTRUCTION, DEVELOPMENT, INSTALLATION &

FINAL OPERATION/ PRODUCTION

SO

CIO

-ECO

NO

MIC

ISSU

ES

MO

NIT

OR R

EVIE

W

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4.1 SITE CONNECTIVITY Table-4.1 Connectivity from Project Site

The details of the industries and site bearings with other facilities available in the vicinity of the industry are as follows

Sl. No.

Industry/Facility Direction from the project site

1. KIADB area North

2. 15 m wide road East

3. Private land West

4. 15 m wide road South

5. Group Pharmaceutical 0.25 km, east

6. Malur Tubes Pvt. Ltd. (MS pipes) 0.25 km, south

7. Cauvery Petrochemical 0.5 km, north

8. Medo Pharma 0.5 km, east

The project site is well connected with roadways. The Bangalore- Malur road is at a distance of

around 2Km east of the project site. The McNally road is at a distance of 1Km North-east of the

project site.

CHAPTER 4 SITE ANALYSIS

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Fig- 4.1 Google Map Showing Connectivity to Project Site Note: All distances mentioned are aerial.

Project site

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4.2 LAND FORM, LAND USE & OWNERSHIP

M/s. Somu Organo-Chem Pvt. Ltd. at No.20, 29th Main, II Stage, I Phase, BTM Layout, Bangalore-560 076 is a proposes to expand its process of hydrogenation, formulations and processing of fine and specialty chemicals industry at Shed No.C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District.

4.3 TOPOGRAPHY M/s. Somu Organo-Chem Pvt.Ltd., is located at latitude of 125856.71"N &

longitude 7, 75,504.70"E at an elevation of 897 m above MSL. The topo map showing the

location of the project site is appended as fig 4.2.

Fig-4.2 Topo Map

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4.4 EXISTING LAND USE PATTERN

Table 4.2 Existing Land Use Pattern

Sl. No. Particulars Area (m2)

1 Total plot area 5,532.91 (100%)

2 Ground coverage area 2,693.04 (48.68%)

3 Hard paved area 1419.94 (25.66%)

4 Landscaped area 1419.94 (25.66%)

5 Built-up area 2,693.04

Note: Land Records are appended in Annexure A

4.5 EXISTING INFRASTRUCTURE

The list of existing infrastructure at the project site is 1. Water supply from Bore well 2. Power supply is from BESCOM 3. Storm water drainage system is provided

4.6 SOIL CLASSIFICATION

The soils of Bangalore Rural districts are broadly classified in to four categories viz (i). Loamy soil (ii) Lateritic soil (iii) Lateritic gravelly soil and (IV) Red sandy soil. Red loamy soils generally occur on hilly to undulating land slope on granite and granite gneisses. Lateritic soil occurs in undulating terrain forming plain to gently sloping topography of peninsular gneiss region. Lateritic gravelly soils occur in upland regions of lateritic soils, Red sandy soil occurs in undulating land slopes. These soils are derived from acidic rocks granites and granitic gneiss.

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4.7 CLIMATIC DATA FROM SECONDARY SOURCES

Table 4.3: Meteorological Data of Kolar for the Year 2015 Mont

h Temperature

0C Relative

humidity % Precipitation

rate (mm/hr)

Atmospheric pressure (mb)

Wind speed (m/s)

Inversion / mixing height

(m)

Cloud cover

(tenths) Min Max Max Min Min Max Min Max Min Max Day Night Min Max

Jan 12.4 25.6 84.8 58.3 0 1.27 909 919 0 6.7 2303 2477 2 10 Feb 13.1 28.9 76.9 44.8 0 1.52 908 915 0 5.1 2517 1786 2 5 Mar 16.4 29.5 69 38.8 0 1.02 907 917 0 6.2 2798 2057 2 6 Apr 18.2 30.8 76.7 50.7 0 3.81 908 914 0 5.1 2910 1799 2 5 May 18.5 32 82.7 61.0 0 2.54 905 913 0 6.2 3319 2317 2 5 June 17.9 30.9 88.6 71.7 0 4.83 904 913 0 10.3 2828 4000 2 10 July 17.4 29.4 89 75.5 0 3.81 904 912 0 8.7 2691 3638 2 10 Aug 17 28.5 88.9 74.5 0 4.06 904 912 0 7.2 2678 2779 3 10 Sept 17.2 29.5 91.4 75.3 0 2.29 905 912 0 7.2 2802 2801 2 10 Oct 16.8 28.8 88.5 73.5 0 2.03 904 913 0 5.7 2575 2046 3 10 Nov 16.8 25.9 93.5 78.1 0 3.81 905 915 0 6.2 2177 2247 2 10 Dec 11.8 24.4 87.6 66.8 0 1.52 906 914 0 6.7 1756 2522 2 10

4.7.1 Temperature The mean maximum temperature is observed at (32°C) in the month of May and the mean

minimum temperature at (11.8°C) is observed in the month of December. In the summer

season the mean minimum temperature is observed during the month of March (16.4°C).

During the monsoon the mean maximum temperature is observed to be 30.9°C in the month of

June with the mean minimum temperature at 17°C during August. By the end of September

with the onset of post monsoon season (October - November), day temperatures drop slightly

with the mean maximum temperature at 28.8°C in October and mean minimum temperature is

observed at 16.8°C for both October & November. The values are presented in table 4.3.

4.7.2 Relative Humidity

Minimum and maximum values of relative humidity have been recorded. The minimum

humidity is observed to be at 38.8% in the month of March and the maximum is 91.4% in the

month of September. The mean minimum values of humidity during summer, monsoon, post-

monsoon and rainy seasons are 38.8%, 71.7%, 73.5% & 44.8% during the months of March,

June, October and February respectively. Similarly the maximum values are 82.7%, 91.4%,

93.5%, 87.6% in the months of May, September, November & December during the summer,

monsoon and post monsoon & winter seasons. The values are presented in table 4.3.

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4.7.3 Rainfall

The monsoon in this region usually occurs twice in a year i.e. from June to September and from

October to November. The maximum annual rate of precipitation over this region ranges

between 1.02 to 4.83 mm/hr.

4.7.4 Atmospheric Pressure

The maximum and the minimum atmospheric pressures are recorded during all seasons. In the

summer season, the mean maximum and minimum pressure values are observed to be 917 mb

in the month of March and 905 mb in the month of May respectively. During monsoon season,

the maximum pressure is 913 mb and minimum 904 mb. The maximum pressure during the

post-monsoon season is observed to be 915 mb in November and minimum pressure is 904 mb

in the month of October. During the winter season the minimum atmospheric pressure is 906

mb in December and the maximum is 919 mb in the month of January. The values are

presented in table 4.3.

4.7.5 Inversion Height

The maximum inversion heights at the project site during the day time & night time for all the

months of the year is as given in the table 3.1. The maximum mixing height of 4000 m is

observed during the month of June during the night time and 3319 m during the month of May

during the day time. The minimum inversion heights are 1756 m in the month of December

during the day and 1786 m during the night in the month of February.

4.7.6 Cloud cover

The minimum cover measured in the unit of tenths is 2 and the maximum observed cloud cover

is 10.

4.7.7 Wind

The data on wind patterns are pictorially represented by means of wind rose diagrams for the entire year as figure 4.3 (for different seasons).

Predominant wind directions

Season Period Wind direction Summer March to May North West

Monsoon June to September East

Post monsoon October to November South West

Winter December to February North West

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4.8 SOCIAL INFRASTRUCTURE

Infrastructure is the basic physical and organizational structures needed for the operation of a

society or enterprise or the services and facilities necessary for an economy to function.

The term typically refers to the technical structures that support a society, such as roads, water

supply, sewers, electrical grids, telecommunications and so forth and can be defined as "the

physical components of interrelated systems providing commodities and services essential to

enable, sustain or enhance societal living conditions”.

Viewed functionally, infrastructure facilitates the production of goods and services and also the

distribution of finished products to markets, as well as basic social services such as schools and

hospitals; for example, roads enable the transport of raw materials to a factory.

Infrastructure facilities The infrastructure and amenities available in the area reflects the economic wellbeing of the region

Educational facilities: The educational facilities available in and around the study area include good number of primary, middle, high school and junior colleges with good facilities apart from Anganwadies in rural sectors.

Communication facilities: The study area and its surroundings have sufficient post and telegraph offices, public telephone booths.

In addition to the above the study area and the villages surrounding it have been provided with good electrical power supply for domestic, industrial, agricultural and public lighting purposes. An electrical substation has been provided by the KSSIDC to ensure the power supply to the industries for most part of the day.

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Fig 4.3: Wind Rose Diagrams

1. March to May (summer season)

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2. June to September (monsoon season)

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3. October to November (post monsoon season)

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4. December to February (winter season)

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CHAPTER 5

PLANNING BRIEF

5.1 PLANNING CONCEPT

M/s. Somu Organo-Chem Pvt. Ltd,. proposes to expand its process of hydrogenation, formulations and processing of fine and specialty chemicals industry within the existing facility at Shed No.C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District.

5.2 POPULATION PROJECTION The expansion and modification will be done in existing facility and no construction activity is envisaged.

Total no. of people employed during operation phase:

Existing: 60 workers

Proposed: 75 workers

5.3 LAND-USE PLANNING The land use planning is given in Table 5.1

Table 5.1: Land-Use Pattern

Sl. No. Particulars Area (m2) In %

1 Total plot area 5532.91 100%

2 Ground coverage area 2,693.04 48.68%

3 Hard paved area 1419.94 25.66%

4 Landscaped area 1419.94 25.66%

5 Built-up area 2,693.04 -

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5.4 ASSESSMENT OF INFRASTRUCTURE DEMAND 1. Malur-Hosur road is at 1.11 Km from the project site towards east

2. National highway 207 is at 10.37Km from project site towards south east

3. National highway 4 is at a distance of 14km from project site towards south west

4. Hoskote-Malur road is at a distance of about 4Km west of the project site

5. The project is in designated industrial area with internal roads in the industrial area and

project site is already available.

5.4.1 Water supply & sewerage infrastructure Water demand for the industry is from tankers and existing Bore well.

The domestic sewage generated is treated in septic tank and sent to soak pit.

The industrial effluents are stored in two collection tank of each about 40,000 L capacity and sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and disposal.

5.5 AMENITIES/FACILITIES Proper site services such as with Drinking water, safety equipments & first Aid is provided to

the workers.

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CHAPTER 6

PROPOSED INFRASTRUCTURE

6.1 INDUSTRIAL AREA (PROCESSING AREA) M/s. Somu Organo-Chem Pvt. Ltd. proposes to expand its process of hydrogenation, formulations and processing of fine and specialty chemicals industry within the existing facility at Shed No.C-29, C-30 & adjacent plots, KSSIDC Industrial Estate, Malur- 563 130, Kolar District.

6.2 GREEN-BELT An area of 696.36 Sq.m of total plot area is green-belt/landscape development. About 52 trees of various native/indigenous variety are already planted. Another 20 trees are proposed in the expansion project, 6.3 SOCIAL INFRASTRUCTURE Details Given in Chapter- 4, section 4.8 6.4 CONNECTIVITY The site is well connected with roadways. NH-207 & NH-4, Hosur-Malur road and Hoskote-

Malur road, Bangalore- Malur road which are at close proximity from the project site enabling

easy transportation of materials to and from the industry.

6.5 SEWERAGE SYSTEM Sewage pipes are laid in entire company for the removal and disposal of mainly non harmful

liquid wastes from the offices and domestic waste, these liquid wastes are sent to septic tank &

soak pit.

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6.6 INDUSTRIAL WASTE MANAGEMENT

The industrial effluents are stored in two collection tank of each about 40,000 L capacity and

sent to Common Effluent Treatment Plant (CETP) of M/s. Eco Engineering for treatment and

disposal.

6.7 SOLID WASTE MANAGEMENT The domestic wastes are segregated at source, collected in bins and handed over to KSSIDC for scientific disposal. Hazardous solid waste will be stored in HDPE bags and sent to authorize reprocessors.

6.8 POWER REQUIREMENT & SUPPLY SOURCE The total power requirement of the industry is 459hp or 342kVA which is sourced from

BESCOM. Further, a diesel generator of 250 kVA capacity is installed to serve as an alternative

source of power supply to this unit.

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CHAPTER 7

REHABILITATION & RESETTLEMENT PLAN M/s Somu Organo-Chem Pvt. Ltd. is in a designated industrial area. The expansion will be within

the existing facility. No home outstees/land outstees are expected & hence no rehabilitation

plan is envisaged.

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CHAPTER 8

PROJECT SCHEDULE & COST ESTIMATES 8.1 TIME SCHEDULE M/s Somu Organo-Chem Pvt. Ltd. is in a designated industrial area. The expansion happening within the existing facility, the industry proposes the addition of new products to its process line. The industry does not particularly emphasize on the time schedule since it is already under operation and only planning to include the production of certain new products to its process line. Table 8.1 Time Schedule

Particulars Time schedule

Start of construction activity Existing plant

Completion Existing facility

8.2 ESTIMATED PROJECT COST The proposed project expansion cost would be Rupees 4.34crores.

Table 8.2 Proposed Expansion Cost

Sl.No. Description Value in Lac.

1 Civil & Structure 60

2 Plant Equipments 80

3 Utility Equipment 45

4 Process & Utility pipelines 25

5 Scrubbing system 9

6 Environment & Effluent Equipments 10

7 R& D and QC Lab instruments 90

8 Electrical 15

9 Insulation and paint 10

10 GMP Powder processing Plant 90

Total Rs 434

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CHAPTER – 9

ANALYSIS OF PROPOSAL

Observing the demographic pattern of the study area it can be inferred that occupational pattern is a mixture more of agriculture rather industrial. The proposed project will increase the employment potential by creating direct and in-direct employment opportunities and thus be beneficial for the local and nearby populace The management of the industry gives preference to local people with both direct and indirect employment.

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