1. INTRODUCTION TO BIOBARICA
2. MEDICAL PRESENTATION 3. TECHNICAL PRESENTATION
BIOBARICA SYSTEM
BioBarica System
Modern high-efficiency therapeutic equipment
Training and Total Support Technical - Medical - Commercial -
Scientific
About us BioBarica is a global network of hyperbaric medicine centers. Our efforts are aimed at expanding the access to high-quality hyperbaric treatment.
✓ We facilitate the incorporation of a universal treatment to the institution.
✓ We allow the doctor to continue doing his / her job. ✓ We incorporate technology and provide the know-how and support.
What does BioBarica offers The Biobarica system facilitates the incorporation of an efficient treatment in anddiyion to the necessary know-how to operate and successfully manage an hyperbaric medicine unite.
We use hyperbaric chambers of medium pressure, 1.4 ATA, of high therapeutic efficiency and complete diffusion to all the tissues.
The Global BioBarica system optimizes the management of the centers and provides all the necessary information to the network.
We offer an integral and constant service for the establishment and growth of hyperbaric medicine centers.
addressed to:
➢Hospitals
➢Public and private health institutions
➢Private offices that incorporate the brand and the benefits of the network
➢Clinics and medical centers, including internal treatment services
➢Physiatry Units
➢Rehabilitation and sports recovery centers
➢Private investors dedicated to developing their own assistance networks
✓ Rehabilitation
✓ Traumatology
✓ Oncology
Where do we work:
Application areas:✓ Rheumatology
✓ Neurology
✓ Medical clinic
✓ Child
Neurology
✓ Wounds and
Burns
BioBarica - Endorsed Therapeutic Efficiency Our hyperbaric chambers are certified by the most important international organizations:
Exclusive Advantages of Revitalair 430
Therapeutic efficacy similar to high pressure
Front camera access
Stretcher for patients without mobility
Vision 360 degrees.
Double compressor with air cooling
Easy operation
Assembly by the user
No installation costs
No maintenance costs
BioBarica Global System
BIOBARICA COMMUNITY
Biobarica provides all the necessary elements for the institution to generate protocols and clinical cases according to international research standards.
We provide the researcher with protocol designs, backup material for control and publication, and biochemical markers for patient control. We allow the researcher to continue with his / her assistance activity, providing the knowledge and the information research.
We provide the institution and its professionals with support protocols for each pathology.
BioBarica Clinical Research
BioBarica Communication
We are the most important network of hyperbaric medicine in the world. We know that communication is fundamental for the development of this activity. That's why we design communication materials segmented by audience: operators, doctors and patients.
We work to develop messages based on concepts tested by a market research. We adapt communication to the cultural needs of each region.
We provide communication support to commercial managers for the network growth.
Participation in fairs and medical congresses around the world
Contractual Responsibility BioBarica signs contracts with the entire network to ensure the correct operation and treatment of patients, guaranteeing:
✓ A suitable service for patients
✓ Correct support provision
✓ Distributors Service
✓ Clarity in the agreement between the parties
Experience in the field of hyperbaric medicine and treatment efficiency supports us and allows us to transmit knowledge to all health institutions.
The incorporation of a BioBarica System gives institutions and doctors the leadership to develop their full potential while our model makes it easily sustainable.
BioBarica develops hyperbaric medicine worldwide
We are the integral option to incorporate the hyperbaric treatment into your institution
HYPERBARIC MEDICINE
1. BIOBARICA INTRODUCTION 2. MEDICAL PRESENTATION 3. TECHNICAL PRESENTATION
HYPERBARIC CHAMBER
Medical device used in TOHB,
to administer oxygen (O2) at
h i g h p r e s s u r e , a b o v e
atmospheric (1 ATM).
HYPERBARIC OXYGEN THERAPY
Like sparkling mineral water, gas bubbles in a closed bottle are not seen until you open the bottle. This is the Henry's physical law that says the gases are diluted in the liquid when they are under pressure. The same happens when we breathe O2 (gas) in a pressurized cabinet (container) and O2 gas is diluted in the blood plasma which is 50% water, generating a strong Hyperoxia.
The hyperbaric chamber has over 200 years and this new category of chambers manages to expand its use to other specialties, facilitating its incorporation to the institution at an efficient cost with high acceptance of patients.
How does the hyperbaric chamber work?
DALTON'S LAW
The pressure of a mixture of
gases is equal to the sum of
the partial pressures (Pp) of
each of the gases that
compose it.
HENRY´S LAWGases dissolve in liquids
when subjected to
pressure.
OXYGEN PHYSIOLOGY Physicochemical fundamentals
Increasing the concentration of O2 we inspire
Increasing the pressure of the air we breathe (environment ≥1.4 ATM) *
O2 100% HIPERBARIA
↑↑↑ O2 dissolved in blood HIPOXIA
Reaches poorly irrigated tissues producing other physiological effects
HYPERBARIC OXYGEN TREATMENT (HBOT)
*Undersea and Hyperbaric Medicine Society
O2 content in blood
The hyperbaric effect on dissolved oxygen:
1. Normobaric Air (21% O2 1 ATA 97% Hb): 0.3ml / dl dissolved oxygen 2. Hyperbaric oxygen (100% 1.4 ATA 100% Hb): 2.4ml / dl dissolved oxygen
HIPEROXIA: ▪ Increases 8 times the amount of dissolved oxygen (independent of
hemoglobin) ▪ O2 is immediately and completely available to cells.
PHYSIOLOGICAL EFFECTS
! O2 gradient between the alveolus and pulmonary capillary
! Diffusion of O2 and availability in tissues
O2 blood pressure and amount of dissolved O2: HYPEROXIA (independent of hemoglobin)
HYPERBARIC OXYGEN
GENERATES A STRONG HIPEROXY
BRINGS PHYSIOLOGICAL BENEFITS
HYPROXY - PHYSIOLOGICAL EFFECTS
VASOCONSTRICTION
ANGIOGENESIS
OSTEOGENESIS
CELL IMMUNITY
PERIPHERAL AXONAL REGENERATION
COLLAGEN SYNTHESIS
OXIDATIVE STRESS AND INFLAMMATORY RESPONSE
NEURONAL FUNCTION AND CEREBRAL BOOD FLOW
CELL PROLIFERATION AND STIMULATION OF STEM CELLS
INJERSES AND COLGAJOS
OXYGEN DOSE
The therapeutic effect of hyperoxia is determined by
the dose of oxygen. In turn the dose of oxygen
depends on:
▪ O2 %
▪ Session length
▪ Frequency of session
▪ Total number of sessions
1 weekly sessions
3 weekly sessions
4 weekly sessions
2 weekly sessions
5 weekly sessions
HIP
ERO
XIA
TREATMENT INDICATIONSessions
Usually a minimum of 10-20 sessions are indicated, according to the pathology of each
patient.
Session length
The average time used is 60 minutes. In acute patients 90-minute sessions are performed up
to 2 times a day.
Sessions cycle
Number of sessions to be performed indicating: total number, daily amount, weekly periodicity
(1 to 6) and session length.
Intercycle period
Rest indicated between cycles.
HBOT: INDICATIONS - MEDICAL CLINIC
✓ Fibromyalgia
✓ Chronic Fatigue
✓ Migraines and headaches
✓ Tinnitus
✓ Geriatrics
✓ Sleep Apnea
✓ Crohn's disease
Adjuvant treatment that reduces inflammation and edema, relieves pain, improves tissue perfusion, energy efficiency and life quality.
HBOT: INDICATIONS - TRAUMATOLOGY
✓ Trauma
✓ Pre and Post-Surgical
✓ Progressive bacterial gangrene
✓ Acute traumatic ischemia
✓ Ligament injuries
✓ Osteomyelitis
Adjuvant treatment that accelerates recovery and healing, reduces inflammation and edema, relieves pain, reduces the infection and amputation risk, and improves life quality.
HBOT: INDICATIONS -SPORT MEDICINE
The adjuvant treatment prepares athletes during training, improves energy efficiency, shortens recovery, prevents fatigue and improves injury rehabilitation.
✓ Training
✓ Muscle and tendon injuries
✓ Post-exercise recovery
✓ Chronic Fatigue Syndrome
HBOT: INDICATIONS - NEUROLOGY
✓ ACV
✓ Parkinson's Disease
✓ Multiple sclerosis
✓ Alzheimer disease
The adjuvant treatment reduces edema, redistributes blood flow and improves brain oxygenation, reduces spasticity and tremors, improves cognitive function, neuroprotection and life quality.
Pediatric Patients:
✓ Autism
✓ GTD
✓ Cerebral palsy
✓ Detoxification
HBOT: INDICATIONS - WOUNDS
✓ Wounds
✓ Ulcer - Diabetic foot
✓ Venous ulcers
✓ Post-Surgical Wounds
✓ Burns
✓ Grafts and implants
The hyperbaric oxygenation treatment accelerates healing, promotes angiogenesis,
reduces inflammation and edema, stimulates collagen synthesis, triggers the immune
response and improves perfusion.
HBOT: INDICATION - RHEUMATOLOGY
✓ Fibromyalgia
✓ Rheumatoid arthritis
✓ Osteoarthritis
✓ Bone edema
✓ Bone necrosis
✓ Osteomyelitis
Adjuvant treatment to speed up recovery, relieve pain, reduce inflammation and edema, decrease the risk of infection and improve life quality.
HBOT: INDICATION - ONCOLOGY
✓ Tumors
✓ Radio-necrosis and radiotherapy
Adjuvant treatment to improve sensitivity to radio and chemotherapy, control
tumor growth, relieve pain, prevent and recover radio-necrosis, and improve life
quality.
EVIDENCE AND CASE PRESENTATION
Several trials, series and case reports highlight the efficacy of
HBOT as a successful treatment for different diseases.
Shai Efrati1,2,3*, Gregori Fishlev1, Yair Bechor1, Olga Volkov3,4, Jacob Bergan1, Kostantin Kliakhandler5, Izhak Kamiager3,6, Nachum Gal1, Mony Friedman1, Eshel Ben-Jacob2,5,7, Haim Golan3,4
Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients - Randomized, Prospective Trial
A normal, healthy adult brain
should be seen primarily in the
SPECT scanner.
Green indicates lower blood
flow and oxygen.
Blue and violet represent a
significant reduction of blood
flow in the brain.
Patient: Male.
Age: 60 years.
Diagnosis: Ischemic ulcer - Rheumatoid arthritis
Number of sessions: 40
Patient: Male.
Age: 27 years old.
Diagnosis: Arteriovenous fistula
Number of sessions: 34
Patient: Male.
Age: 60 years.
Diagnosis: Post-surgery heart
Number of sessions: 35
Patient: Male.
Age: 60 years.
Diagnosis: Lower limb, Necrosis, circulatory failure.
Number of sessions: 20
Patient: Male.
Age: 5 years.
Diagnosis: Arteriovenous malformation
Number of sessions: 70
Patient: Male
Age: 70 years.
Diagnosis: Diabetic ulcer
Number of sessions: 70
Patient: Woman.
Age: 90 years.
Diagnosis: Gluteal scar
Number of sessions: 35
Patient: Woman.
Age: 60 years.
Diagnosis: Pyoderma gangrenosum
Number of sessions: 40
Patient: Woman.
Age: 11 years.
Diagnosis: Trauma
Number of sessions: 40
Patient: Woman.
Age: 70 years.
Diagnosis: Lip melanoma
Number of sessions: 20
Patient: Male.
Age: 90 years.
Diagnosis: Venous insufficiency
Number of sessions: 20
➢ Absolute ▪ Pneumothorax in the Treaty ▪ Lung bulla
➢ Relative ▪ Tympanic Perforation ▪ Oncologic treatment (Bleomycin, Cisplatin, Doxorubicin, Disulfiram) ▪ Pacemaker
➢ Special cares ▪ Mild hypoglycemic hypertension ▪ Congestion or catarrh ▪ Claustrophobia ▪ Pathology of VAS and COPD
CONTRAINDICATIONS
HYPERBARIC TREATMENT WITH REVITALAIR CAMERAS 430
In the daily use we verify the therapeutic efficacy of HBOT in healthy patients through
scientific research.
➢ Treatment at 1.4ATA does not modify the biochemical parameters of the acute phase
inflammation or the oxidative stress in healthy volunteers. Significant increase of
antioxidant enzyme suggests the effect of hyperoxia in healthy patients.
➢ The fluctuations of biochemical parameters at 10 and 20 sessions are kept within
reference values: physiological response conserved in healthy volunteers.
➢ Treatment is safe and well tolerated, with no adverse effects.
CONCLUSION:
The strong HYPROXIA increases the dissolved oxygen volume in blood plasma. This increase in O2 diffusion reaches less irrigated tissues.
Hyperoxia produces a wide chain of PHYSIOLOGICAL BENEFITS in the body.
HYPERBARIC TREATMENT: The patient breathes high doses of O2 in a hyperbaric environment.
INSTALLATION AND OPERATION OF THE
HYPERBARIC CAMERA
1. BIOBARICA INTRODUCTION 2. MEDICAL PRESENTATION 3.TECHNICAL PRESENTATION
HYPERBARIC CHAMBER: COMPONENTS
➔ Components: • Pressurizing booth • Cabin Compressor • Support Table • BioBarica Support Systems
➔ Optional: • Stretcher for patients with low mobility. • O2 concentrator or O2 tube • Web monitoring system • Extended warranty.
Read User's Manual carefully . It has everything you need and will guide you step by step on how to operate and maintain this high tech medical device.
INSTALLING A HYPERBARIC CAMERA
BioBarica recommended brands:
- Airsep - Intensity 10 model - High flow - 10 liters per minute.
- Novo 10 - Nidek Medical - High flow - 10 liters per minute.
- OxyBreath 10L - Hikooneb® - High flow - 10 liters per minute.
OXYGEN CONCENTRATOR
Mask with disposable reservoir recommended for maximum therapeutic efficiency.
➢ We recommend that you use the closed mask with reservoir and with the exhaust valves plugged.
➢ This mask delivers 100% of the O2 available.
➢ The more O2 inspires the patient the more effective the treatment will be.
➢ Some children do not like to use the mask and they have to be placed buttresses but this reduces the concentration of O2 by 50%.
OXYGEN MASKS
Hyperbaric chamber maintenance The maintenance is done by the same operator of the equipment with the instructions that generates the BioBarica global system. The on-line system notifies the operator of all the necessary maintenance for the equipment to function properly.
Technical support The BioBarica network accesses the extended factory warranty up to 4 years (optional) and in case of a problem the replacement is sent immediately. In case of having a technical problem, BioBarica replaces the product. Its network of distributors has all the elements to provide the local service immediately.
Guarantee The chamber comes with factory guarantee for 1 year except the door lock system which has a lifetime guarantee. If the customer wishes, he can purchase the extended guarantee for 4 years.
TECHNICAL SPECIFICATIONS
Treatment pressure
You can lower the treatment pressure but you can not raise it. The equipment operating in
standard form only works at 1.4 ATM but in some cases the doctors decide that it is necessary
to work at lower pressure and open the outlet valve 1 or 2 points and the internal pressure
stabilizes in values between 1.1 and 1.4 ATM according to indications.
Which is the difference with rigid chambers?
Rigid chambers are used with high pressure. This requires high maintenance costs and a
specialized operator. Also by being a highly pressurized equipment, the safety requirements
are very high. Furthermore, the treatment is more aggressive and stressful for the patient.
TECHNICAL SPECIFICATIONS
Advantages of Revitalair 430 compared with low pressure chambers
In the market there are low pressure 1.3 ATM chambers that are offered at very low prices.
Ours are medical equipment certified to 1.4 ATM which is the minimum pressure for hyperbaric
treatment.
Which is the difference with rigid chambers?
Rigid chambers are used with high pressure. This requires high maintenance costs and a
specialized operator. Also, for being a pressurized equipment, the safety requirements are very
high and the treatment is more aggressive and stressful the patient.
Chamber Operation
The equipment is ready to run all day. It only rests 5 minutes per hour which is the time in
which a patient leaves and another enters.
* The UHMS of the United States defines hyperbaric treatment starting from 1.4 ATM
Revitalair 430
• 1.42 ATA* • 150Kg • 95% de patologías
High pressure
• 3 ATA • +1500 kg • 100% de patologías
Low pressure
• 1.3ATA • 45-60Kg • 30% de patologías
Revitalair 430 High Pressure Chamber
✓ Revitalair 430 hyperbaric chambers are easy to operate and manipulate by the user without assistance.
✓ Safety: They have greater internal air flow and 4 safety valves.
✓ You can enter these chambers with any type of clothing.
✓ You can also enter with books and electronic devices (cell phone, Tablet, etc).
- High pressure hyperbaric chambers require a specialized technician to operate them.
- Due to their operation in high pressure, they require many safety measures.
- You must enter the camera with cotton clothes because of the static.
- Entry with electronic devices is prohibited.
Hyperbaric chamber Revitalair 430 Low pressure chamber
✓ Entrance System, door lock patented (system guarantee for life).
✓ Removable stretcher. Ease of entry for people with reduced mobility.
✓ Children can enter accompanied by an adult.
- Zipper system, less durable and does not achieve complete sealing.
- Located on the ground, making it difficult for people with reduced mobility to enter. They do not have a stretcher.
- Due to space, only one person per session is allowed.
Installation: Revitalair 430® chambers are assembled in little time and do not require much space. The minimum required measures are 1.70m x 2.80m.
Maintenance: These chambers are easy to maintain and clean by the user.
Operation: easy to operate and do not produce claustrophobia.
High-pressure chambers require special space, of greater size and complexity.
They also require regular hydraulic testing for maintenance and specialist technicians.
These high pressure chambers weigh approximately 1000kg and are dangerous to operate.
IMPORTANT
How many patients can be treated per month in one chamber?
• An average patient needs 14 sessions for a treatment. • Standard session time is 60 minutes. • The device is operated 10 hours a day 22 days a month = 220 Hs. • 220 Hs. / 14 sessions per patient = 15.7 patients per month. • Time between sessions: 10 minutes plus agenda problems = 15% of the time.
Final patients that can be treated per month = 14 patients
BIOBARICA CENTER
Infrastructure: Simple room in the institution or private consultation.
Air conditioner: Normal for patient comfort.
Cleaning: Appropriate to a health institution.
Training and Support: BioBarica Global System - Hipermed
Operational guide of a BioBarica center
BioBarica Global System - BGS - is management interactive software that solves the
market needs by disseminating Know-How to distributors, medical institutions and
operators, and allowing the permanent contact of the entire network.
BIOBARICAL GLOBAL SYSTEM
BIOBARICAL GLOBAL SYSTEM
Hipermed
Tickets
Training
Blog
Maintenance
HIPERMED
▪ It allows to do a statistical follow-up of each patient treatment
▪ The statistically collected data shows an automated report by pathology
▪ The system delivers a treatment protocol for each pathology
TRAINING
BioBarica provides all the necessary knowledge to start ups and treatment center operators.
The system provides training and support for:
➢ Doctors ➢ Nurses ➢ Operators ➢ Technicians ➢ Researchers ➢ service staff ➢ commercial
TICKETS The Tickets module is an effective communication channel for physicians, operators, commercials and researchers to request material, services and advice. It provides a channel with the distributors and central BioBarica for all the necessary support.
MAINTENANCE Maintenance is performed by the operator with the assistance of the integrated maintenance system. This module will guide the person designated by the institution in the correct way to maintain the equipment. The guide is graphic and interactive. It can be done by any maintenance person, operator or cleaning staff.
BioBarica typical session
Click on the image to see the video
BIOBARICA
Modern equipment of high therapeutic efficiency
+
Training and Total Support
✓Technical ✓Medical ✓Commercial ✓Scientific
THANK YOU FOR TRUSTING IN BIOBARICA