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From Behaviour to Brain to Gene … and back again Presented by Richard Hill MA www.richardhill.com.au
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From Behaviour to Brain to Gene
… and back again
Presented by
Richard Hill MA
www.richardhill.com.au
a woman without her man is nothing
• A woman, without her man, is nothing.
• A woman: without her, man is nothing.
Gene expressionEpigenetic silencing
• State dependent gene expression• Activity dependent gene
expression• Epigenetic marking – methylation,
acetylation. Access of transcription factors to promoter region.
• Nucleosome tension – ionic tightness.
We construct ourselves
From elemental materials
Over time
In response to experience
Becoming Human
DNA + experience
Biology + activity Behaviour
The deep psychobiological process of “activity or experience-dependent gene expression and brain plasticity” associated with creativity and psychotherapy.
Psychosocial Genomics
Interactive – responsive
biochemicals
Responsive to
experience – adaptive
Hierarchy of response
Responses are
remembered* meaning *
Self Organising SystemsInitial Conditions – DNA, polymorphisms
Organising Principles
Self Organising Systems
Optimal• Immune system• Associative brain• Positive emotions• Seeking• Social brain
Adaptation• Dis-integration• Hierarchy of needs• Habituation• Automation /
normalisation
How We RememberImplicit /
Explicit
Neuronal / Neural
Biological
Bio-chemical
Fascia
Muscles
Skin OrgansImmune System
Brain
Mind – Body MemoryConnected
systems
Implicit ExpressionBehaviour
Affect (emotionality /
mood)
PersonalityTemperament
Sense of Wellness -
pain
9 Voices
Skin Sleep Sun
Sugar Sitting Stress
Sex Pain Face
EMBODY
the
UNTRUE
TRUTH
ARGUE
the
UNTRUE
TRUTH
The Interplay
DNA + experience
Biology + activity Behaviour
The Interplay
BRAIN
BODY
Endocrine System
Neuropeptidespeptides
Autonomic System
Immunesystem
CNS (spinal) Vagus nerve
MINDThe Interplay
C.O.A.T. Curiosity Oriented Approach To…
That’s interesting
The problem is a message
What can I create from this
The Purpose of Life
To creatively participate in the experience
