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mxxkhdmqj.=Tzg`/Tdg` Xcd. xqmll yjxjmyhc mxxkhdmqj.= Htydnn Ckygzxx. yjxjmyhc ljnnkp.= Knd|jy Ymaej. mqqjgadg`

vctxdhdmg.=.8 Gmqcmg N Vmhj.vykljxxky.=.1 Hcydxqdmg H Mvljn. mxxkhdmqjvykljxxky= Kg ijcmnlkl qcjVjydkvjymqd|j

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jlldhmhdkzx mvvykmhc lky vyj|jgqdg` vmdg kg dgbjhqdkg klvykvklkn'

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Amqm xkzyhjx VziOja. Joimxj. Hkhcymgj Ndiymyt.

ppp'hndgdhmnqydmnx'`k|. mga cmga xjmyhcdg` lyko qcj

yjljyjghj ndxqx kl dajgqdldja vmvjyx'

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dgqjy|jgqdkg qk mnnj|dmqj vmdg kg dgbjhqdkg kl vykvklkn dg

maznqx'

Yjxznqx Amqm pjyj mgmntxja lyko =00 ymgakodxja

hkgqyknnja qydmnxqkqmnndg`9: 9

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Qk odgdodxj amqm azvndhmqdkg mx m yjxznq kl oznqdvnjyjvkyqdg` pj hkovmyja vmvjyx lyko qcj xmoj mzqcky'Dg maadqdkg.pj xjmyhcjappp'hndgdhmnqydmnx'`k|lky xqz/adjx' Qpk mzqckyx #NB mga \E$ xhyjjgja mga yjqydj|jayjvkyqx mga jshnzaja dyyjnj|mgq xqzadjx' Yjnj|mgq amqmpjyj jsqymhqja it kgj mzqcky #\E$ mga hcjheja it

mgkqcjy #NB$' Maadqdkgmn dg|jxqd`mqkyx #HHM. KY. mgaGNV$ vmyqdhdvmqja dg qcj yj|djp vykhjxx pcjg zghjy/qmdgqt mikzq jnd`didndqt hydqjydm mykxj' Lyko jmhc xqzatpj jsqymhqja ajqmdnx kg vmqdjgqx hcmymhqjydxqdhx #maznqxkgnt$. zxj kl gkg/ayz` dgqjy|jgqdkgx #lky jsmovnj. xdqjkl |jgkzx hmggznmqdkg. xvjja kl dgbjhqja vykvklkn.qjo/vjymqzyj kl dgbjhqja vykvklkn$. zxj kl mgmn`jxdh dgqjy/|jgqdkgx. mga zxj kl hkoidgmqdkgx kl dgqjy|jgqdkgx#xjj pji jsqym 9 lky hcmymhqjydxqdhx kl dghnzaja xqzadjx$'

Xjnjhqdkg kl xqzadjx lky yj|djp

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qd|j hkgqykn. mga yjvkyqja qcj yjxvkgxj ymqj mga xj|jy/dqtkl vmdg dg maznqxyjhjd|dg` dgqym|jgkzx vykvklkn'Mnndghnzaja xqzadjx cma gzojydhmn amqm vyjxjgqja dg qcjqjsq ky m qminj5 dl amqm pjyj gkq vyjxjgqja mx xzhc. pjjsqymhqja qcj dglkyomqdkg lyko qcj `ymvcx dl qcj xhmnjmnnkpja m xzlldhdjgqnt vyjhdxj jxqdomqdkg' Pj dghnzajamnn xqzadjx qcmq ojq qcj jnd`didndqt hydqjydm. yj`myanjxx klnmg`zm`j kl vzindhmqdkg'

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Xqmqdxqdhmn mgmntxdx

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xckpg qk ij xd`gdldhmgq dgad|dazmnnt' Qcj vydomyt kzq/hkoj pmx qcj gzoijy kl vmqdjgqx yjvkyqdg` mgt vmdg

VziOja #g?914$Azvndhmqjx #g?8$Ada gkq ojmxzyj vmdg lyko

vykvklkn dgbjhqdkg #g?36$

Joimxj #g?938$Vyj|dkzxnt dajgqdldja #g?=38$Ada gkq ojmxzyj vmdg lyko

vykvklkn dgbjhqdkg #g?1

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#vmdg yjxvkgxj ymqj$5qcj jlljhq xdrj pmxqcj yjnmqd|j ydxe'Pj ada gkq hmyyt kzq ojqm/mgmntxjx kl vmdg xhkyjx #lkyjsmovnj. gzojydhmn ky |jyimn ymqdg` xhmnjx$ ijhmzxjqcjt pjyj yjvkyqja ikqc ymyjnt mga dghkgxdxqjgqnt'Lky xqzadjx pdqc oznqdvnj dgqjy|jgqdkg `ykzvx. pj vmy/qdqdkgja qcj hkzgq kl j|jgqx mga vmqdjgqx dg qcj hkgqykn`ykzv dgqk qpk ky okyj hkgqykn `ykzvx pdqcdg mgtojqm/mgmntxdx qk m|kda m zgdq kl mgmntxdx jyyky' Xdod/nmynt. lky qcj xqzadjx vmyqdhdvmqdg` dg qcj dgadyjhq hko/vmydxkgx. pj vmyqdqdkgja qcj hkovmymqky `ykzvmhhkyadg` qk ckp omgt qdojx dq pmx zxja lky dgadyjhqhkovmydxkgx #mhykxx ojqm/mgmntxjx$' Qcj xzoomytyjnmqd|j ydxex mga 4:* hkgldajghj dgqjy|mnx pjyj jxqd/omqja zxdg` m ymgako jlljhqx Omgqjn/Cmjgxrjnojqcka dg Yj|Omg :'6 #HkhcymgjHknnmikymqdkg$' Xqm/qdxqdhmn cjqjyk`jgjdqt pmx mxxjxxja it qcj D9 |mnzj' Dldgqjy|jgqdkgx dg|kn|ja =6 ky okyj xqzadjx. pj zxjalzggjnvnkqxqk |dxzmndxjxomnn xqzat jlljhqx ky yjvkyqdg`

idmx5 mxtoojqyt pmx qjxqja zxdg` qcj myhxdgj qymgxlky/omqdkg mga ojqcka kl okojgqx ndgjmy yj`yjxxdkgdovnjojgqja dg qcj Y vmhem`j ojqm #Y Lkzgamqdkglky Xqmqdxqdhmn Hkovzqdg`. Mzxqydm$'=6 Pj hkgxdajyjaV |mnzjx njxx qcmg 6'6: mga yjnmqd|j ydxex gkq hykxxdg`qcj dajgqdqt ndgj mx xqmqdxqdhmnnt xd`gdldhmgq'

Pj mgmntxja qcj gjqpkye kl ymgakodxja hkgqyknnjaqydmnx pdqcdg mg dgadyjhq hkovmydxkg lymojpkye zxdg`vyj|dkzxnt ajxhydija okajnx== mga dovnjojgqja dglyj}zjgqdxq odsja jlljhqx ojqmyj`yjxxdkg=95 pj xjnjhqjakgnt dgqjy|jgqdkgx qcmq xd`gdldhmgqnt yjazhja vmdg it madyjhq dgqjy|jgqdkg hkovmydxkg pdqc xds ky okyjdghnzaja xqzadjx' Qcj xzoomyt xqmqdxqdh pmx qcj yjnm/qd|j ydxe. pdqc 4:* hkgldajghj dgqjy|mnx' Qcj hkookghkovmymqky pmx qcj vnmhjik ky hkgqykn `ykzv' Qcjokajymqkyx dg qcj odsja jlljhqx okajnx pjyj qcjdgqjy|jgqdkgx jgqjyja mx hmqj`kydhmn hk|mydmqjx'Mxxzovqdkgx dg qcdx mgmntxdx dghnzaja m xzlldhdjgqckok`jgjdqt kl qcj adlljyjgq qydmnx. qyjmqojgq jlljhqx#nk`YY$ adxqydizqja gkyomnnt mykzga m qtvdhmn |mnzj.mga qcj xmoj yjxdazmn cjqjyk`jgjdqt #9$ mokg` qcjokajymqkyx' Qcdx mgmntxdx pmx hmyydja kzq zxdg` qcj Yvmhem j ojqmlky zxdg` yjxqydhqja omsdozo ndejndckkajxqdomqdkg #xjj pji jsqym 8 lky ajqmdnx kl qcj okajn$'Pj mabzxqja qcj qjxq xqmqdxqdhx kl dgad|dazmn jxqdomqjxkl okajymqky |mydminjx mga kogdizx ctvkqcjxjx kl mnnokajymqkyx it qcj ojqcka kl Egmvv mga Cmyqzg` #qmga L adxqydizqdkgx$'=8 Yjxdazmn cjqjyk`jgjdqt pmxmxxjxxja it 9 qjxqx' Mx qcj ojqckax kl jxqdomqdkg myjadlljyjgq. qcj yjnmqd|j ydxe |mnzjx lyko Yj|Omg mgaojqmlky adlljy xnd`cqnt'

YJXZNQX

M xjmyhc kl VziOja. Joimxj. mga Hkhcymgj amqm/imxjx dajgqdldja 6'66=

6'6: #6'66 qk 6'04$

6'60 #6'66 qk ='60$

6'60 #6'6= qk 6'13$

6'60 #6'6= qk 6'13$

6'13 #6'=1 qk ='

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Qminj 8 ~ Jlldhmht yjxznqx kl ayz` dgqjy|jgqdkgx qk yjazhj vmdg lyko vykvklkn dgbjhqdkg

Dgqjy|jgqdkg Hkgqykn

Gk kl

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#4:* HD$

Cjqjyk jgjdqt D9

#*$.

V |mnzj Yjljyjghjx

9 m`kgdxq vyjqyjmqojgq Gk vyjqyjmqojgq 9 =3= 6'3= #6'

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dajgqdldja qcykz`c VziOja #qcyjj pjyj azvndhmqjx mga36 ada gkq ojmxzyj vmdg lyko vykvklkn dgbjhqdkg$. 994

kl qcj 938 dajgqdldja qcykz`c Joimxj #=38 pjyj dajg/qdldja dg qcj vyj|dkzx xjmyhc mga 1< ada gkq ojmxzyj

vmdg lyko vykvklkn dgbjhqdkg$. mga =6: kl qcj =19 dajg/qdldja qcykz`c qcj Hkhcymgj amqmimxjx #43 pjyj vyj/|dkzxnt dajgqdldja mga xj|jg ada gkq ojmxzyj vmdglyko vykvklkn dgbjhqdkg$' Dg maadqdkg qk qcj 9:0 vkqjg/qdmn xqzadjx m lzyqcjy 91 pjyj dajgqdldja mlqjy cmgaxjmyhcdg` yjljyjghjx kl yjnj|mgq vmvjyx. mga qpk pjyjlyko qcj ZX `k|jygojgq hndgdhmn qydmnx pjixdqj#ppp'hndgdhmnqydmnx'`k|$' Qczx. 938 xqzadjx pjyjyjqydj|ja mx vkqjgqdmn hndgdhmn qydmnx lky lzyqcjy j|mnzm/qdkg' M lzyqcjy =6< xqzadjx pjyj jshnzaja lky qcj lkn/nkpdg` yjmxkgx2 yj|djpx #xj|jg xqzadjx$.=81=1/=0 gkqhmyydja kzq dg czomgx #g?9$. =3=4 gkq ymgakodxjahkgqyknnja qydmnx #g?=:$. 96/81 dovykvjy mxxjxxojgq klvmdg #g?0$. 8:/1= azvndhmqj vzindhmqdkg #g?9$. 1918 ojqck/aknk`dhmn hkghjygx #g?=:$. 11/:4 ada gkq ojmxzyj vmdgkg dgbjhqdkg kl vykvklkn #g?96$. 6'66=. D9?3=*

Qjxq lky k|jymnn jlljhq2 r?6'66=. D9?04*

Qjxq lky k|jymnn jlljhq2 r?4'4:. V>6'66=

6'64 #6'69 qk 6'81$

6':= #6'9: qk ='61$

6'== #6'6: qk 6'98$

6'19 #6'98 qk 6'00$

6'61 #6'66 qk 6'

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=4 xzihmqj`kydjx imxja kg ayz` hnmxxlky jsmovnj.mgqdjojqdhx. nkhmn mgmjxqcjqdhx. ijgrkadmrjvdgjx. imy/idqzymqjx' Okxq kl qcjxj ayz`x pjyj vmyqdmnnt xzhhjxxlzndg yjazhdg` qcj ydxe kl vmdg lyko vykvklkn dgbjhqdkg'

M ndakhmdgj/vykvklkn maodsqzyj #9: qydmnx$ pmx qcjokxq jlljhqd|j dgqjy|jgqdkg dg qcdx xzihmqj`kyt #6'16.6'88 qk 6'13. ld` 8$' =9:=9

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Vyjqyjmqojgq pdqc kvdkdax xckpja mgmn`jxdh ijgjldq#6'14.6'1= qk 6':4. ld`6'66=$. mikzq 11* kl qcj yjxdazmn cjqjyk`jgjdqtcma ijjg mhhkzgqja lky it qcj dghnzxdkg kl qcj jd`cq

Ndakhmdgj : o` / 96 o` vyjqyjmqojgqMamhcd 9669

Mamhcd 9669

OhAkgmna =446'66=. D9?

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Hndgdhmn dovndhmqdkgx

Imxja kg qcj hkovmydxkgx hmyydja kzq cjyj. dq xjjoxqcmq mokg` qcj pdaj myymtx kl dgqjy|jgqdkgx qjxqja.jd cq cma xzlldhdjgq j|dajghj kl ijgjldq' Pcjg

dgqjy|jgqdkgx xjjo xdodnmynt jlldhmhdkzx. hckdhjx lkydgqjy|jgqdkg hmg ij omaj kg lmhqkyx xzhc mx hkxq. vjy/xkgmn hckdhj. mga xdovndhdqt kl mvvndhmqdkg'

Kzy yjxznqx kl adyjhq mga dgadyjhq hkovmydxkgx xz`/`jxq m vkxxdinj xqymqj t qcmq dx ikqc jlldhmhdkzx mga jmxtqk mvvnt dg hndgdhmn vymhqdhj #ld` ==$' Xdghj kvdkdax myj

zxja hkookgnt mx vmyq kl m imnmghja mgmjxqcjxdm vyk/qkhkn. dq xjjox yjmxkgminj qk zxj qcjo mx ykzqdgj vyj/ojadhmqdkg dg vyjvmymqdkg lky dgazhqdkg lky mnn qcyjjkvqdkgx. mx qcjt cmn|j qcj ydxe kl vmdg lyko vykvklkndgbjhqdkg #yjnmqd|j ydxe 6':6$' Pj ak gkq yjhkoojgaqcj zxj kl gkg/xqjykdamn mgqd/dglnmoomqkyt ayz`x mxqcj yjxznqx lky qcjxj m`jgqx pjyj cjqjyk`jgjkzx mgaxkoj qcjoxjn|jx hmzxj vmdg kg dgbjhqdkg' Kgjmvvykmhc hkzna ij qk zxj mg mgqjhzidqmn |jdg. pcjg/j|jy vymhqdhminj. pdqc dqx yjnmqd|j ydxe yjazhqdkg klmikzq 3:*' Imxja kg qcj mxxzovqdkg qcmq dgqjy|jgqdkgxkl dgajvjgajgq vmqcpmtx pkye dgajvjgajgqnt. 911 qcjydxe kl vmdg kg dgbjhqdkg dx ndejnt qk ij kgnt :* pcjg

vyjkvjymqd|j kvdkdax myj hkoidgja pdqc qcj mgqjhzid/qmn mvvykmhc #6'66=. D9?

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hkgbzghqdkg pdqc vyjqyjmqojgq zxdg` ndakhmdgj kyejqmodgj ijlkyj qcj dgbjhqdkg kl m vykvklkn joznxdkghkgqmdgdg` ojadzo mga nkg` hcmdg qyd nthjydajx.qcjyjit mnxk yjazhdg` qcj ydxe kl vmdg qk mikzq=6/=9* #6'66=Qjxq lky xzi`ykzv adlljyjghjx2 Gkq mvvndhminj

6'03 #6'6'66='

YJXJMYHC

IOB ~ KGNDGJ LDYXQ ~ iob'hko vm`j == kl =3

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Pj qcmge Pknl`mg` \djhcqimzjy #Xhckkn lky Vzindh Cjmnqc mga Vydomyt

Hmyj. Ommxqydhcq Zgd|jyxdqt. qc j Gjqcjynmgax$ lky qcj xtgqms kl my`zojgqx

zxja dg qcj Y vmhem`j ojqmlky5 Am|da Okcjy #Kqqmpm Ckxvdqmn Yjxjmyhc

Dgxqdqzqj. Zgd|jyxdqt kl Kqqmpm$ lky vyk|dg` hydqdhmn dgvzq lky qcj xqzat5 mga

Xmezym Edgbk #Zgd|jyxdqt kl Hmndlkygdm Xmg Lymghdxhk$ lky qymgxnmqdg` qcj

Bmvmgj xj o mgzxh ydvqx ' Yj |Omg :'6 #Yj| djp O mgm`jy . H khcym gj

Hknnmikymqdkg. ZE$ xqmqdxqdhmn vmhem`j pmx zxja dg qcdx xtxqjomqdh yj|djp

lky mgmntxdx' Maadqdkgmnnt. qcj Y vmhem`jx ojqmlky mga ojqm pjyj zxja #Y

Aj|jnkvojgq Hkyj Qjmo #96=6$' Y2 M nmg`zm`j mga jg|dykgojgq lkyxqmqdxqdhmn hkovzqdg`' Y Lkzgamqdkg lky Xqmqdxqdhmn Hkovzqdg`$'

Hkgqydizqkyx2 \E. NB. TTX. KY. mga HHM pykqj qcj xqzat vykqkh kn' NB mga \Ehknnjhqja mga hknnmqja qcj amqm' HHM mga GNV vyk|daja xqmqdxqdhmn

jsvjyqdxj' HHM. NB. mga GNV mgmntxja mga dgqjyvyjqja qcj amqm' NB. TTX.

J@. HC. HHM. mga GNV aymlqja qcj myqdhnj' NB. J@. TTX. HC. HHM. KY. mga

GNV hydqdhmnnt yj|dxja qcj myqdhnj lky dovkyqmgq dgqjnnjhqzmn hkgqjgq' NB. J@.

TTX. HC. HHM. mga G NV vy k|daj a mao dgdxq ymqd| j. q jhcgd hmn. ky n k`dxq dh

xzvvkyq' Mnn mzqckyx mvvyk|ja qcj ldgmn myqdhnj. cma lznn mhhjxx qk mnn qcj

amqm #dghnzadg` xqmqdxqdhmn yjvkyqx mga qminjx$. mga hmg qmej yjxvkgxdidndqt

lky qcj dgqj`ydqt kl qcj amqm mga qcj mhhzymht kl qcj amqm mgmntxdx' HHM. NB.

mga GNV myj qcj `zmymgqkyx'

Lzgadg 2 Qcdx xqzat pmx lzgaja it qcj Vjydkvjymqd|j Hndgdhmn YjxjmyhcHkyj. Zgd|jyxdqt kl Hmndlkygdm. Xmg Lymghdxhk'

Hkovjqdg` dgqjyjxqx2 Mnn mzqckyx cm|j hkovnjqja qcj Zgdldja Hkovjqdg`Dgqjyjxq lkyo mq ppp'dhobj'ky`+hkd[adxhnkxzyj'val mga ajhnmyj qcmq NB.

\E. J@. TTX. HC. KY. mga HHM cm|j xzvvkyq lyko qcj Vjydkvjymqd|j

Hndgdhmn Yjxjmyhc Hkyj. Ajvmyqojgq kl Mgmjxqcjxdm mga Vjydkvjymqd|jHmyj. Zgd|jyxdqt kl Hmndlkygdm. Xmg Lymghdxhk. HM lky qcj xziodqqja pkye5

NB. \E. J@. TTX. HC. GNV. KY. mga HHM cm|j gk yjnmqdkgxcdvx qcmq od`cq

cm|j mg dgqjyjxq dg qcj xziodqqja pkye dg qcj vyj|dkzx 8 tjmyx5 qcjdy

xvkzxjx. vmyqgjyx. ky hcdnayjg cm|j gk ldgmghdmn yjnmqdkgxcdvx qcmq omt ij

yjnj|mgq qk qcj xziodqqja pkye5 mga NB. \E. J @. TTX. KY. mga HHM cm|j gk

gkg/ldgmghdmn dgqjyjxqx5 mga GNV dx mg zgvmda xqmqdxqdhmn jadqky lky m

Hkhcymgj Hknnmikymqd|j Yj|djp @ykzv'

Jqcdhmn mvvyk|mn2 Gkq yj}zdyja'Amqm xcmydg`2 Qcj qjhcgdhmn mvvjgads. xqmqdxqdhmn hkaj. mga amqmxjq myjm|mdnminj lyko qcj hkyyjxvkgadg` mzqcky mq mvljnhFmgjxqcjxdm'zhxl'jaz'

= Omyde VJ' Vykvklkn2 qcjymvjzqdh dgadhmqdkgx mga xdaj/jlljhqx' HzyyVcmyo Ajx 96615=6286'66=

6'=3 #6'63 qk 6'16$

6'89 #6'=: qk 6'6'66=

6'60 #6'6= qk 6'14$

6'=8 #6'6: qk 6'88$

6'=: #6'6< qk 6'83$

6'=8 #6'6: qk 6'94$

6'96 #6'=6 qk 6'1=$

6'94 #6'=: qk 6'::$

6'1= #6'91 qk 6'06$

6'81 #6'9= qk 6':

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=4 Jydexxkg O. Jg njxxkg X. Ckyqj D. Cmyq|d` V' Qcj mgmjxqcjqdh vkqjghtkl vykvklkndg qcjymq dx yjazhja it xdoznqmgjkzx dgqym|jgkzxmaodgdxqymqdkg kl nd`gkhmdgj' Jzy B Mgmjxqcjxdkn =4445=

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==3 Ekimtmxcd T. Qxzhcdam M. Emomam T. Xjed X. Dhcdodtm Q. GmodedM'Jlljhqx kl xvjja kl dgbjhqdkg kg mgjxqcjxdm dgazhqdkg pdqc vykvklknmga ljgqmgtn' Omxzd=4445132310/:='

==4 XhkqqYV. Xmzgajyx AM. Gkyomg B' Vykvklkn2 hndgdhmn xqymqj`djx lkyvyj|jgqdg` qcj vmdg kl dgbjhqdkg'Mgmjxqcjxdm =4335182149/1'

=96 XqkejxAG. Ykixkg G. CzqqkgV' Jlljhqkl adnzqdg` vykvklkn kg qcjdghdajghj kl vmdg kg dgbjhqdkg mga |jgkzx xj}zjnmj' Iy B Mgmjxqc=4345

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=08 Ntkgx I. Nkcmg A. LntggH. OhHmyyknn O' Okadldhmqdkgkl vmdg kgdgbjhqdkg kl vykvklkn' M hkovmydxkg kl vjqcdadgj mga nd`gkhmdgj'

Mgmjxqcjxdm =44

7/31/2019 Prevention of Pain on Injection of Propofol: systematic review and meta-analysis

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99< Xjqcd G. Bmtmymomg N. Xjqcd O. Xcmyom X. Xkka B' Vyj|jgqdkg klvykvklkn vmdg2 m hkovmymqd|j xqzat' Odaanj Jmxq B Mgjxqcjxdkn966459620=/1'

990 TjpPX. Hckg` XT.Qmg EC.@kc OC'Qcj jlljhqx kl dgqym|jgkzxndakhmdgj kg vmdgazydg` dgbjhqdkg kl ojadzo/ mga nkg /hcmdgqyd`nthjydaj vykvklkn joznxdkgx'Mgjxqc Mgmn 966:5=662=

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938 AjadhM. Mamo X. @koojyxA. \mgIkoojnB' Vykvklkndgbjhqdkgvmdgdx dq xqdnn mg dxxzj;Qcj jlljhqkl vyjojadhmqdkg' Odgjy|m Mgjxqjxdkn96=650