Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillators in Children

and Adolescents With Hypertrophic Cardiomyopathy

Presented By: Jennifer Glen, Mi Hae Kim, Rosangel Vargas

Overview

● Objectives● Background● Methods● Results● Conclusion● Critiques● Q&A

Objective

● To determine the efficacy of ICDs in children and adolescents with HCM

Background

● What is HCM?● HCM is the most

common cause of SD in children and young adults

Implantable Cardioverter Defibrillator (ICD)

Types of ICDs

Abbreviations and Acronyms

HCM - Hypertrophic CardiomyopathyICD - Implantable Cardioverter DefibrillatorLV - Left VentricleLVH - Left Ventricular HypertrophySD - Sudden DeathVF - Ventricular FibrillationVT - Ventricular Tachycardia

Methods

● Patient Selection● Defibrillators● Risk Factor Analysis

Results

● Baseline Characteristics ● ICD interventions /Timing● Drugs● Risk Factor Analysis

Discussion

● History of HCM Studies● In this study…

o Children and Adolescents ( < 20 years )o Effective 20 % ( ≈ 90% with No or mild Symptoms)

● Who gets ICD among HCM patientso Extreme LVHo Syncopeo Family Historyo Hypotensive BP response to exerciseo NSVT

Conclusion

● Successful ! ● Pros and Cons

Critiques

● Data ● Words

Reference

Maron BJ, Spirito P, Ackerman MJ, Casey SA,Semsarian C, Estes M, Shannon KM, Ashley EA, Day SM, Pacileo G, Formisano F, Devoto E, Anastasakis A, Bos JM, Woo A, Autore C, Pass RH, Boriani G, Garberich RF, Almquist AK, Russell MW, Boni L, Berger S, Maron MS,Link MS. 2013. Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defilbrillators in Children and Adolescents With Hypertrophic Cardiomyopathy. Journal of American College of Cardiology (No.14) [Internet]. [2013 April 09, cited 2015 March 13] Vol. 61. Available from: http://content.onlinejacc.org/mobile/article.aspx?articleid=1673454

Questions?