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Product Training Guide

UNITED STATES

2 PRODUCT TRAINING GUIDE UNITED STATES

©2017 Nerium International™, LLC. All Rights Reserved. R0617

COMPANY BACKGROUNDNerium International was founded in 2011 with the vision of “Making People Better.” From the very beginning, our corporate culture and product offerings have reflected our commitment to improve people’s lives. It’s simple: We want our customers to look and feel their best. Our age-fighting products allow them to do just that.

OUR PRODUCT PHILOSOPHY: EXCLUSIVE PRODUCTS THAT DELIVER EXCEPTIONAL RESULTSAt Nerium, we provide best-in-class, age-fighting products, tailor-made to deliver visible results, while also fitting your busy lifestyle. This means we invest and partner with key scientific organizations to research, develop and create multifunctional products that offer exceptional results, while addressing many different signs of aging at once.

HOW TO USE THIS GUIDEWe created this guide as a one-stop resource to help you locate key information about our products offered in the United States. You can use this guide in a number of ways:

1. To learn about the Nerium product line. 2. As a reference guide for key ingredient information. 3. As a quick way to access Frequently Asked Questions regarding specific products, ingredients, usage instructions, etc.

WHAT SETS US APART FROM OTHER ANTI-AGING COMPANIES? Our product formulas are based on patented, exclusive ingredients that no other company can use or duplicate. The benefit? Proprietary, cutting-edge products that are not available anywhere else.

A SCIENTIFIC FOUNDATION Nerium is rooted in science. Our promise is to provide proven, age-fighting products powered by the most advanced ingredients available.

RESEARCH & DEVELOPMENT: WE LEAD THE WAY IN ANTI-AGING INNOVATIONWhile we incorporate a number of tried-and-true ingredients into our formulas, we don’t stop there. We use exclusive ingredients created, developed and tested by the world’s top universities and scientific labs.

PRODUCT TECHNOLOGYOur products are powered by proprietary technology that harnesses the best from science and nature. We use exclusive, patented ingredients with proven antioxidants, peptides, plant extracts and vitamins to craft products that target multiple signs of aging. It’s a customized approach that allows us to develop products that go beyond addressing the signs of aging to also target the underlying causes.

FORMULATIONSThe key to our formulas is based on the use of ingredients originally developed in the biotechnology field that have been adapted for the anti-aging industry.

THE NERIUM SKINCARE FORMULA DIFFERENCE Each of Nerium’s age-defying skincare products: 1. Addresses both the signs of aging as well as the underlying causes,

providing effective short- and long-term results. 2. Contains powerful antioxidants. 3. Works to address multiple signs of aging with one product.

OUR 360 VIEW Our goal to offer a comprehensive, age-fighting product line has evolved into a new, totally holistic approach with our expansion into the nutritional space. Our wellness supplements work in tandem with our coveted skincare products to help you look and feel healthy, inside and out.

The Nerium Difference: Nerium Delivers Anti-Aging Breakthroughs

Creating Opportunities for a Better You

PRODUCT TRAINING GUIDE UNITED STATES 3


NAE-8® (NERIUMAD® FORMULA) Years of biotechnology research led to this accidental discovery. Researchers discovered that the unique properties of the nerium oleander plant provided remarkable, age-defying results when applied topically to the skin. The patented NAE-8 extract, derived from the nerium oleander and aloe vera plants, acts as a powerful antioxidant and boosts the cell renewal process to reveal younger-looking skin.

EHT® BRAIN FORMULA Developed after more than 20 years of scientific research*, Princeton University professor Dr. Jeffry Stock discovered EHT, a mix of bioactive molecules isolated from coffee. His investigation suggests the EHT molecule optimizes the function of PP2A, a key protein that helps keep neuronal connections in the brain strong and healthy.*

SIG-1191™ Developed by Dr. Jeffry Stock, SIG-1191 is a patented, exclusive ingredient that works as a super antioxidant.

COMPLEX NAA™ An antioxidant-rich blend that offers immune support, and brighter, healthier-looking skin.

YOUTH FACTOR™ ENZYME BLEND This proprietary blend of digesive enzymes helps unlock the age-fighting properties of the foods you eat by supporting the optimal bioavailability of antioxidants and polyphenols.

SIG-1273® (OPTIMERA™ FORMULA)** Twenty years of research by Dr. Jeffry Stock led to the creation of a remarkable age-defying molecule. This progressive molecule was perfected after 1,272 versions and patented as the advanced, age-fighting ingredient SIG-1273.

The basis of SIG-1273 comes from the observation of naturally occurring compounds. It includes an organic phytol compound that acts as a super antioxidant and skin protectant, which actually mimics and boosts the skin’s natural age-fighting mechanism.

Key Discovery Stories

* Source: Signum’s R&D Experimental Biology Conference* *Optimera is Nerium’s international formula and is not available in the United States.



WHAT’S IN IT? Key Ingredient Function

NAE-8 A patented, proprietary extract and powerful antioxidant derived from nerium oleander and aloe vera that helps reduce the appearance of fine lines and wrinkles.

Aloe barbadensis leaf juice

This nutrient-rich ingredient forms the base of the formula. It’s highly emollient and a well-known source of moisture and hydration.

Peptide matrix A blend of collagen, elastin and glycosaminoglycans that helps restore skin’s firmness.

Vitamin E (tocopherol) A potent antioxidant that helps protect the skin from free radicals and UV damage.

Castor seed oil A natural, super-hydrating oil that softens the skin.

Hydrolyzed quinoa Helps guard against environmental stressors and soothes irritated skin.

Rice bran oil Rich in vitamin E and fatty acids; helps fight free radicals.

Olus oil Moisturizes the skin and acts as a barrier to moisture loss.

Age-Defying Night Cream NeriumAD® FormulaWHAT IS IT? A clinically tested, age-fighting product containing a high concentration of our exclusive, patented NAE-8® extract. In addition to this exclusive ingredient, our Night Cream is formulated with a mix of antioxidants, plant extracts and vitamins to target multiple signs of aging.

WHAT DOES IT DO?• The Night Cream, powered by our proprietary NAE-8 extract:

◦ Addresses the signs of aging, as well as the underlying causes ◦ Acts as a powerful antioxidant and works to target free radical damage ◦ Boosts the cell renewal process to reveal younger-looking skin ◦ Gently adheres to skin for maximum delivery of the key ingredients with a unique mask-like quality ◦ Addresses both the existing and future signs of aging, resulting in younger-looking skin

• Fights the appearance of: Fine lines • Wrinkles • Discoloration • Uneven skin texture • Enlarged pores • Sagging skin • Perfect for use on: Face • Neck • Décolletage • Hands • Ideal for all skin types: Non-comedogenic • Dermatologist tested

IN INDEPENDENTLY CONDUCTED CLINICAL TRIALS:• 93% of participants showed significant improvement in the

appearance of their wrinkles. • 92% of participants showed significant improvement in their

skin’s radiance. • 72% of participants showed significant improvement in skin

discoloration.

WHAT’S NOT IN IT?Parabens, colorants, DEA, propylene glycol, fragrance.

WHEN AND HOW DO I USE IT?• Age-Defying Night Cream is designed for application at night,

when skin is in its rest-and-repair cycle. • After cleansing skin thoroughly, apply 4–5 pumps of product to

face and neck. Apply to slightly damp skin for optimal absorption. Rinse skin the morning following usage.

• For optimal results, use with our Age-Defying Day Cream, NeriumAD Formula.

PRODUCT FEATURES:• This product is multifunctional and perfect for women and men

of any age. It’s the ultimate anti-aging cream that treats multiple signs of aging in one step and offers visible results that continue to improve over time.

• Unlike most night creams, this product won’t rub off when your head hits the pillow. It stays in place, working overnight.

• The Night Cream incorporates a high percentage of botanical ingredients, which creates the nature-based aroma.

• Net weight: 30 ml/1 fl. oz.

Ingredients: NAE-8 Nerium Aloe Extract (Aloe Barbadensis Leaf Juice, Nerium Oleander Leaf), Peptide Matrix (Collagen, Elastin, Glycosaminoglycans), Oryza Sativa (Rice) Bran Oil, Stearic Acid, Glycerin, C14-22 Alcohols, Glyceryl Stearate, Ricinus Communis (Castor) Seed Oil, Cetyl Alcohol, Olus Oil, Cetearyl Glucoside, Cetearyl Alcohol, Sodium Borate, Carrageenan, Dicaprylyl Ether, Hydrolyzed Quinoa, Sodium Isostearoyl Lactylate, Dimethicone, Carrageenan, C12-20 Alkyl Glucoside, Water (Aqua), Sodium PCA, Caprylyl Glycol, Fragrance (Parfum), Glyceryl Caprylate, Tocopherol, Phenylpropanol, Sodium Hydroxymethylglycinate.

The information on this page is for product training in the United States based on country-specific regulatory compliance.




NAE-8 A patented, proprietary extract and powerful antioxidant derived from nerium oleander and aloe vera that helps reduce the appearance of fine lines and wrinkles.



Peptide blend Helps smooth the look of existing wrinkles and supports natural collagen production. CoQ10 (Ubiquinone) An antioxidant that helps support natural, healthy collagen production. Jojoba esters Lightweight, natural moisturizer for long-lasting hydration. Sodium hyaluronate Naturally present in the skin, binds water to skin for volume and firmness. Green tea A well-known antioxidant that guards against environmental damage. Vitamin E (tocopherol) A potent antioxidant that helps protect the skin from free radicals. Vitamin C (tetrahexyldecyl ascorbate) A vitamin known for its antioxidant and skin-brightening properties.

Superoxide dismutase A potent antioxidant that guards against free radical damage.

Age-Defying Day CreamNeriumAD® Formula

IN INDEPENDENTLY CONDUCTED CLINICAL TRIALS:• 93% of participants had a significant increase in skin moisture. • 86% of participants had an improvement in uneven skin texture. • 86% of participants noted a reduction in pore size.


WHEN AND HOW DO I USE IT?After cleansing skin, apply 4 pumps to face and neck. Use once each morning. Product may be applied throughout the day and to other body areas as a moisturizer.

PRODUCT FEATURES:• The way to get the most effective anti-aging benefits is to use

the Day Cream in conjunction with the Night Cream. • This product is a lightweight formula crafted with non-oily oils.• The sheer texture makes it perfect for women to wear under

their makeup and for men to wear because it won’t show on their skin. It soaks right into the skin without leaving any noticeable residue.

• Net weight: 30 ml/1 fl. oz.

Ingredients: Water (Aqua), NAE-8 Nerium Aloe Extract (Aloe Barbadensis Leaf Juice, Nerium Oleander Leaf), Glycerin, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Cetyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Cetyl Palmitate, Jojoba Esters, Squalane, Dimethicone, Sorbitol, Bisabolol, Glyceryl Caprylate, Cetearyl Glucoside, Sodium Hyaluronate, Pentylene Glycol, Tetrahexyldecyl Ascorbate, Avena Sativa (Oat) Kernel Extract, Santalum Album (Sandalwood) Extract, Phellodendron Amurense Bark Extract, Camellia Sinensis (Green Tea) Leaf Extract, Hordeum Distichon (Barley) Extract, Hydrogenat-ed Lecithin, Tocopherol, Dipotassium Glycyrrhizinate, Allantoin, Superoxide Dismutase, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ubiquinone, Magnesium Chloride, Phenoxyethanol, Xanthan Gum, Disodium EDTA, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Sodium Hydroxymethylglycinate, Potassium Sorbate. May Contain: Aminomethyl Propanol, Citric Acid.


WHAT IS IT? A clinically tested, age-fighting Day Cream powered by our exclusive, patented NAE-8® extract. Our proprietary formula is also packed with antioxidants, peptides and plant extracts that smooth the look of existing fine lines and wrinkles. Specifically created for daytime use, the sheer formula also moisturizes and softens skin.

WHAT DOES IT DO?• The Day Cream, powered by our proprietary NAE-8 extract:

◦ Addresses the signs of aging, as well as the underlying causes ◦ Acts as a powerful antioxidant and works to target free radical damage ◦ Boosts the natural cell renewal process to reveal younger-looking skin ◦ Mimics the skin’s natural age-fighting properties ◦ Binds moisture to the skin for long-lasting lightweight hydration

• Fights the appearance of: Fine lines • Wrinkles • Discoloration • Uneven skin texture • Enlarged pores • Sagging skin

• Perfect for use on: Face • Neck • Décolletage • Hands • Ideal for all skin types: Non-comedogenic • Dermatologist tested



Double-Cleansing BotanicalFace Wash


Sea3C An exclusive blend of sea whip extract, betula platyphylla japonica juice and raffinose, which are known to moisturize the skin.

Coconut-derived surfactants Sulfate-free surfactants that gently, but effectively, help cleanse the skin.

Glycerin Known for its moisturizing and skin-soothing benefits. Rosemary leaf oil Known for its skin-conditioning properties. Niacinamide Known to help even skin tone. Clary sage oil A masking agent known for its calming and soothing benefits.

WHAT IS IT? An advanced, lightweight cleanser that combines the distinct properties of oil with the fresh feeling of a light foam. This gentle product is applied to dry skin, removing oil-based impurities and makeup and then, with the addition of water, transforms into a soft, milky lather for deep down cleansing. This multifunctional facial wash does double-duty as a makeup remover and is delicate enough to be used morning and night.

WHAT DOES IT DO?• Double-Cleansing Face Wash, powered by our proprietary Sea3C™ blend:

◦ Removes makeup and impurities ◦ Provides gentle, yet effective, cleansing ◦ Helps remove the effects of air pollution on the skin’s surface ◦ Has a pH that works in harmony with the skin

• Ideal for all skin types: Dermatologist tested

IN AN INDEPENDENTLY CONDUCTED CONSUMER STUDY:• 96% of participants reported it effectively cleanses skin.• 95% of participants reported it leaves skin feeling smooth. • 93% of participants reported it cleanses skin without drying.• 86% of participants reported it leaves skin looking healthier.• 85% of participants reported it leaves skin looking revitalized.


WHEN AND HOW DO I USE IT?• For optimal results, apply 2-4 pumps to your hands and massage over

dry face. Use gentle, circular motions to melt away dirt, impurities and makeup. Next, add a small amount of water and massage to create a light, milky lather. Rinse thoroughly with lukewarm water.

• Use daily, morning and evening.

PRODUCT FEATURES:• This unique product goes on as an oil and gently lathers with water

to wash away clean, leaving your skin feeling fresh.• This multifunctional product is also designed to remove makeup,

even eye makeup (non-waterproof).• The product’s coconut-derived surfactants are both gentle and

effective and it contains no sodium laureth sulfate and no sodium lauryl sulfate.

• The product is perfect for women and men of any age and can be used morning and night.• Double-Cleansing Face Wash is ideal for cleaning and preparing the skin for Nerium’s Night and Day Creams.• Net weight: 120 mL/4 fl. oz.

Ingredients: Water (Aqua), Glycerin, PEG-75, Cocamidopropyl Hydroxysultaine, Disodium Cocoamphodiacetate, Sodium Chloride, Dipropylene Glycol, Sodium Cocoamphoacetate, PEG-20 Glyceryl Isostearate, Acrylates Copolymer, Sea Whip Extract, Raffinose, Betula Platyphylla Japonica Juice, Niacinamide, Salvia Sclarea (Clary) Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Citrus Grandis (Grapefruit) Peel Oil, Caprylyl Glycol, Disodi-um EDTA, Hexylene Glycol, Butylene Glycol, Citric Acid, PEG-6 Caprylic/Capric Glycerides, Sodium Benzoate, Phenoxyethanol.




WHAT’S IN IT? Key Ingredient FunctionSIG-1191 A patented, exclusive ingredient that works as an antioxidant.

I-FIL4R An exclusive ingredient derived from white lily and Brazilian ginseng that helps reduce the appearance of puffiness, fine lines and dark circles.

Aloe barbadensis leaf juice It’s highly emollient and a well-known source of moisture and hydration.

Advanced peptide Supports the skin’s natural collagen and elastin, which helps skin look fuller and plumper.Caffeine Helps stimulate circulation.Jojoba esters Lightweight, natural moisturizer for long-lasting hydration.Green tea A well-known antioxidant that guards against environmental damage.Sodium hyaluronate Naturally present in the skin; binds water to skin for volume and firmness.Vitamin E (tocopherol) A potent antioxidant that helps protect the skin from free radicals.Vitamin C (tetrahexyldecyl ascorbate) A vitamin known for its antioxidant and skin-brightening properties.

Age-Defying Eye SerumWHAT IS IT? An advanced, multifunctional age-fighting Eye Serum for day and night use that delivers short- and long-term benefits. Powered by the patented SIG-1191™ molecule and I-FIL4R™, derived from white lily and Brazilian ginseng, Nerium’s transformative Eye Serum has a pH level that works in harmony with your skin.

WHAT DOES IT DO?• The Eye Serum, featuring our proprietary SIG-1191™ ingredient:

◦ Delivers an immediate reduction in the appearance of fine lines and wrinkles ◦ Supports the skin’s natural structure ◦ Matches your skin’s natural pH level, ensuring optimal skin health ◦ Firms and brightens the appearance of the eye area

• Fights the appearance of: Dark circles • Puffiness • Lines • Wrinkles• Perfect for use on: The skin around the eyes – especially crow’s feet• Ideal for all skin types: Dermatologist and ophthalmologist tested

IN INDEPENDENTLY CONDUCTED CLINICAL TRIALS:• 89% of participants showed a decrease in the appearance of fine lines

around the crow’s feet area.• 80% of participants showed brighter skin in the eye area.• 67% of the participants showed an improvement in the appearance of

dark circles.

WHAT’S NOT IN IT?Parabens, colorants, dyes, DEA, propylene glycol, fragrance.

WHEN AND HOW DO I USE IT?• After cleansing skin, apply one pump of product per eye in the

morning and evening. Gently smooth the serum around the eye area. While smoothing it on, the product will begin to adhere to skin and fill lines. After a few seconds, stop smoothing in the product and remain expressionless for 30 seconds while the product dries to a soft, even finish.

• For optimal results, use with our Age-Defying Night and Day Creams.

PRODUCT FEATURES:• Age-Defying Eye Serum is a multifunctional product that

works in two ways: 1. Delivers an immediate reduction in the appearance

of fine lines around the eye area.2. With continued use, combats dark circles, puffiness,

lines and wrinkles. • This product is formulated at the pH level most suitable for skin.

This ensures maximum age-fighting benefits in a formula that works in harmony with your skin.

• If applying makeup or concealer to the eye area after using the product, make sure the product has fully dried. Spread makeup around the eye area, patting and smoothing it out using the tip of the ring finger to blend.

• Net weight: 10 ml/0.3 fl. oz. Ingredients: Water (Aqua), Adipic Acid/Neopentyl Glycol Crosspolymer, Dimethicone, Pentylene Glycol, Hydroxypropyl Methylcellulose, Caprylyl Methicone, Tocopherol, Pfaffia Paniculata, Root Extract, Ptychopetalum Olacoides Bark/Root Extract, Lilium Candidum Flower Extract, Porphyridium Cruentum Extract, Camellia Sinensis Leaf Extract, Caffeine, Aloe Barbadensis Leaf Juice, Physalis Pubescens Fruit Juice, Acetylglutaminoyl Farnesylcysteine*, Peg-40 Hydrogenated Castor Oil, Jojoba Esters, Hydrolyzed Jojoba Esters, Adenosine, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Squalane, Dipotassium Glycyrrhizate, Glycerin, Tetrapep-tide-26, Vp/Va Copolymer, Caprylyl/Capryl Glucoside, Pullulan, Potassium Cetyl Phosphate, Peg-12 Dimethicone/Ppg-20 Crosspolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Amodimethicone, Caprylyl Glycol, Sodium Dehydroacetate, Ethylhexylglycerin, Sodium Phytate, Coceth-7, Dimethicone/Vinyl Dimethicone Crosspolymer, Ppg-1-Peg-9 Lauryl Glycol Ether, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copo-lymer, Polysorbate 60, Sodium Hydroxide, Butylene Glycol, Phenoxyethanol, Chlorphenesin, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate, Citric Acid, Phenoxyethanol, 1, 2-Hexanediol, Caprylyl Glycol, Sodium Chloride, Sodium Benzoate.The information on this page is for product training in the United States based on country-specific regulatory compliance.*SIG-1191. US Patent No. 9,376,383.




PhytoLumina A proprietary blend of plant-based ingredients, alpinia officinarum root extract, physalis pubescens fruit juice and bidens pilosa extract, which helps skin look radiant and brighter.

Niacinamide A well-known ingredient for more even-toned looking skin.Kombucha ferment A unique ingredient derived from fermented tea that offers a host of skin benefits.Green tea A well-known antioxidant that guards against environmental damage.Glycerin Derived from lipids, this skin humectant absorbs moisture and protects the skin’s natural barrier.Hydrolized sodium hyaluronate Naturally present in the skin; binds water to skin to improve the appearance of volume and firmness.

Alteromonas ferment extract Helps shield skin from environmental stressors.

Vitamin C (ascorbyl glucoside) A vitamin known for its antioxidant and skin-brightening properties.

Aloe barbadensis leaf juice It’s highly emollient and a well-known source of moisture and hydration.

IllumaBoost™

Brightening & ShieldWHAT IS IT? This innovative booster mixes with your existing products to enhance your skincare regimen in three ways. It helps brighten by fighting the signs of uneven skintone and discoloration, helping skin look radiant and vibrant. It helps protect the skin from environmental stressors and urban pollution. And it includes ingredients that are known for their hydrating benefits, allowing for a flatteringly soft and full appearance.

WHAT DOES IT DO?• IllumaBoost, featuring our proprietary PhytoLumina complex, contains ingredients that:

◦ Work to brighten the skin’s appearance and help even skin tone ◦ Help shield the skin from environmental stressors ◦ Help plump and moisturize the skin

• Fights the appearance of: Discoloration • Uneven skin tone • Skin damage caused by air pollution • Perfect for mixing with: Age-Defying Night and Day Creams, foundation or sunscreen • Ideal for all skin types: Dermatologist tested

IN AN INDEPENDENTLY CONDUCTED CONSUMER STUDY:• 74% of participants reported their skin looked rejuvenated.• 73% of participants reported an improvement in the appearance of skin texture.• 71% of participants reported their skin’s natural glow was restored.


WHEN AND HOW DO I USE IT?• On first use, press the pump down to open the chamber, releasing the

brightening ingredients into the liquid. Shake the container until the formula is completely mixed.

• For optimal results, add 1-2 pumps of product to your Age-Defying Night and Day Creams, foundation or sunscreen. Use morning and evening.

• Use bottle within 15 days. Do not depress the pump to break the chamber until product is ready to use.

PRODUCT FEATURES:• IllumaBoost Brightening & Shield enhances your skincare routine by adding ingredients to your existing products that help brighten and hydrate, plus protect against environmental stressors.• A combination of hydrating ingredients, including hydrolized sodium hyaluronate, also work to help plump and moisturize the skin. • The unique, dual-compartment package seals the niacinamide and vitamin C blend in a separate chamber to preserve freshness until use.• This product is tailor-made to amplify your current skincare products: simply mix a couple pumps with your Night or Day Cream, serum, foundation or sunscreen for a quick boost of skin-benefiting ingredients.• IllumaBoost can also be applied directly to your skin. Its thin texture allows the product to immediately soak into your skin with no sticky or tacky residue.• Net weight: 16mL/0.5 fl. oz. per bottle. 2 bottles per package.

Ingredients:: Water (Aqua), Aloe Barbadensis Leaf Juice, Propanediol, Niacinamide, Erythritol, Hydrolyzed Sodium Hyaluronate, Glycerin, Ascorbyl Glucoside, Alpinia Officinarum Root Extract, Physalis Pubescens Fruit Juice, Bidens Pilosa Extract, Saccharomyces/Xylinum/Black Tea Ferment, Lactobacillus/Soybean Ferment Extract, Alteromonas Ferment Extract, Lecithin, Panthenol, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Dictyopteris Membranacea Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Saccharomyces/Barley Seed Ferment Filtrate, Sac-charomyces/Potato Extract Ferment Filtrate, Hydrated Silica, Hydroxyethylcellulose, Polysorbate 20, Maltodextrin, Gellan Gum, Disodium Edta, Butylene Glycol, Sodium Citrate, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Acrylates/Vinyl Isodecanoate Crosspolymer, Sodium Hydroxide, Phenoxyethanol.




Eye-V Moisture Boost Hydrogel Patches

WHAT’S IN THEM? Key Ingredient FunctionHydromoist* Superior hydrator that helps retain water in the skin. SIG-1191 A patented, exclusive ingredient that works as an antioxidant and skin hydrator.

I-FIL4R An exclusive ingredient derived from white lily and Brazilian ginseng that is known to help reduce the appearance of puffiness, fine lines and dark circles.

Aloe vera leaf water Nutrient-rich water that includes moisturizing and hydrating agents. Glycerin Derived from lipids, this skin humectant absorbs moisture and supports skin’s natural barrier. Echinacea extract Echinacea is a botanical known for its age-fighting and astringent benefits.Lavender Natural botanical known to calm and soothe skin. Green tea A well-known antioxidant that guards against environmental damage.

WHAT ARE THEY? These innovative, super-charged Hydrogel Eye Patches deliver a boost of intensive hydration to the eye area to combat the appearance of puffy, stressed or fatigued eyes. Featuring ThermoReact™ technology, an innovative delivery system that works with your skin’s temperature, and powered by patented ingredients SIG-1191™ and I-FIL4R™, Nerium’s Eye Patches offer benefits that appear like an instant “eye lift.”

WHAT DO THEY DO?• Eye-V Hydrogel Patches’ 5 Key Benefits:

◦ Hydrate the eye area ◦ Brighten the look of the eye area ◦ Firm the look of the skin ◦ Reduce the appearance of puffiness ◦ Diminish the appearance of fine lines

• Fight the appearance of: Dryness • Puffiness • Lines • Wrinkles • Perfect for use on: The skin under and around the eye area• Ideal for all skin types: Dermatologist and ophthalmologist tested

IN AN INDEPENDENTLY CONDUCTED CONSUMER STUDY:• 86% of participants reported the patches felt calming and refreshing to

the skin.• 82% of participants reported the patches provided a boost of

intensive hydration.• 77% of participants reported the patches reduced the appearance of puffiness.

WHAT’S NOT IN THEM?Parabens, colorants, DEA, Synthetic fragrance.

WHEN AND HOW DO I USE THEM?• Open a pouch and pull out the tray containing two delicate eye patches.• With gentle pressure, swipe the tip of your index finger along the “N” side of

the patch to remove it from the tray.• Apply one onto the clean, dry under-eye area. Repeat on other side. (Apply

with the “N” facing away from the skin). • For optimal benefits, use one treatment each week. The patches can also

be used as a quick pick-me-up before date nights, after late nights or after long flights.

• Relax and enjoy for 20 minutes as the ingredients soak into the skin. The patches will stay in place after application, so you can easily move around while wearing them. • Gently remove and discard after use then softly pat remaining serum onto

the skin. NOTE: Product must be used immediately after pouch is opened.

PRODUCT FEATURES:• Can be used as a complement to our Age-Defying Eye Serum for a

complete age-defying eye regimen or as a standalone product.• This hydrating formula is crafted with a high concentration of nutrient-rich

aloe leaf juice water, glycerin and Hydromoist* (polyglutamic acid) to supply moisture to the skin.

• The innovative ThermoReact technology guards and preserves the nourishing ingredients until the patches are applied, delivering key ingredients to the skin. The skin’s natural temperature unlocks the key ingredients for the appearance of an instant “eye lift.”

Ingredients: Aloe Barbadensis Leaf Water, Butylene Glycol, Water, Glycerin, Lavandula Angustifolia Flower/Leaf/Stem Extract, Lilium Candidum Flower Extract, Echinacea Purpurea Extract, Polyglutamic Acid*, Bisabolol,Camellia Sinensis Leaf Extract, Adenosine, Acetylglutaminoyl Farnesylcysteine**, Physallis Pubescens Fruit Extract,Tremella Fuciformis Extract, Scutellaria Baicalensis Root Extract, Pfaffia Paniculata Root Extract, Ptychopetalum Olacoides Bark/Root Extract, Chondrus Crispus Powder, Ceratonia Siliqua Gum, Lepidium Meyenii Root Extract, Lactobacillus Ferment Filtrate, Artemisia Princeps Leaf Extract, Houttuynia Cordata Extract, Citrus Junos Fruit Extract, Peg40 Hydrogenated Castor Oil, 1,2-Hexanediol, Peg60 Hydrogenated Castor Oil, Cellulose Gum, Caprylyl Glycol,Trideceth9, Ethylhexylglycerin, Disodium Edta, Dextrin, Caprylyl/Capryl Glucoside, Pentylene Glycol, Propylene Glycol, Sodium Citrate, Benzyl Alcohol, Potassium Sorbate, Potassium Chloride, Phenoxyethanol.

The information on this page is for product training in the United States based on country-specific regulatory compliance.*Hydromoist (Polyglutamic Acid) is a registered product of Silicones Plus.**SIG-1191: US Patent No. 9,376,383.

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WHAT IS IT?A clinically tested Body Contour Cream powered by our exclusive NAE-8® extract. This breakthrough formula helps firm and tone the appearance of problem areas for a sleeker, more youthful-looking body.

WHAT DOES IT DO?• The Body Contour Cream, featuring our proprietary NAE-8 extract:

◦ Helps smooth and tighten skin for a more toned appearance ◦ Works to improve the appearance of cellulite and dimpled skin ◦ Provides soothing benefits and moisture to your skin, leaving it feeling soft and hydrated

• Key benefits: Smooths • Tightens • Firms • Tones• Perfect for use on: Upper arms • Thighs • Stomach • Love handles• Ideal for all skin types: Dermatologist tested

IN INDEPENDENTLY CONDUCTED CLINICAL TRIALS:• 92% of participants reported positive improvements on their thighs.• 92% of participants reported an increase in skin hydration.• 83% of participants reported an improvement in the appearance

of skin smoothness and cellulite.


WHEN AND HOW DO I USE IT?• Massage a quarter-sized amount of product into each targeted

area in a circular motion for a minimum of 20 seconds or until fully absorbed.

• To maximize results, use twice a day. Optimal times of usage are after a warm shower and before bedtime.

PRODUCT FEATURES:• This breakthrough formula is clinically tested and shown to help

firm, tighten and tone problem areas. • While this product helps target problem areas, it doubles as an

advanced body moisturizer to smooth and hydrate skin. • Net weight: 200 ml/6.7 fl. oz.

Firming Body Contour CreamNeriumAD® Formula


NAE-8 A patented, proprietary extract and powerful antioxidant derived from nerium oleander and aloe vera that helps firm and tone the appearance of problem areas for a sleeker, more youthful-looking body.



Caffeine Helps stimulate circulation to smooth the appearance of dimpled skin.

Peptide matrix A blend of collagen, elastin and glycosaminoglycans that helps restore skin’s firmness.

Forskohlii root oil Helps firm skin to reduce the appearance of dimpling.

White willow bark Known to have astringent and exfoliating benefits.

Shea & cocoa butters Natural moisturizers with superior skin conditioning properties.

Green tea A well-known antioxidant that guards against environmental damage.

Sodium hyaluronate Naturally present in the skin; binds water to skin for volume and firmness.

Ingredients: Water (Aqua), NAE-8 Nerium Aloe Extract (Aloe Barbadensis Leaf Juice, Nerium Oleander Leaf), Ethylhexyl Palmitate, Hydrogenated Polyisobutene, Glycerin, Cetyl Alcohol, Peptide Matrix (Collagen, Elastin, Glycosaminoglycans), Caffeine, Salix Alba Bark Extract, Cetearyl Alcohol, Phenoxyethanol, Camellia Oleifera (Green Tea) Leaf Extract, Isohexadecane, Ceteareth-20, Polysorbate 80, Sorbitan Stearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyltaurate Copolymer, Theobroma Cacao (Cocoa) Seed Butter, Dimethicone, Ethylhexylglycerin, Xanthan Gum, Butyrospermum Parkii (Shea) Butter, Coleus Forskohlii Root Oil, Sodium Hyaluronate, Sodium Hydroxymethylglycinate, Disodium EDTA, Retinyl Palmitate, Tocopheryl Acetate.





EHT This patented extract is a natural mixture of bioactive molecules isolated from coffee that helps strengthen neural connections to promote optimal brain health.**

Vitamin B12 A water-soluble vitamin naturally present in some foods. Vitamin B12 is required for proper red blood cell formation and neurological function.

Vitamin B6 Vitamin B6 plays a role in cognitive development as well as immune function.

Magnesium A mineral crucial to the body’s function. Helps keep blood pressure normal, bones strong and the heart rhythm steady.

Vitamin D Vitamin D is vital to bone metabolism, calcium absorption and other metabolic processes in the body.

Selenium A mineral needed for certain enzymes that help with normal body functions.

Alpha lipoic acid A naturally occurring antioxidant that helps support healthy sugar levels.

Huperzine-A Known to enhance acetylcholine effects, the essential neurotransmitter in the brain responsible for many functions, including cognition and memory. It also protects against free radicals.

WHAT IS IT?EHT Brain Formula is a groundbreaking supplement that includes our exclusive, patented EHT extract. The formula is further fortified with other key ingredients such as vitamins B6, B12, D3, magnesium, selenium, huperzine-A and alpha lipoic acid.*

WHAT DOES IT DO?EHT Brain Formula, powered by the EHT extract, helps keep neuronal connections strong, resulting in improved brain wellness, memory and a focused mind.**

APPROPRIATE FOR: Men and women 18 years of age or older.

WHEN AND HOW DO I USE IT?EHT Brain Formula should be taken once a day (1 tablet), with food, in the morning. EHT works best when taken with foods that contain healthy fats like nuts, avocado or yogurt.

PRODUCT FEATURES:• EHT was developed after 20 years of research by Dr. Jeffry Stock,

a professor at Princeton University.• EHT is decaffeinated.• EHT focuses on B vitamins to sustain and increase energy.• EHT is BSCG certified.• Box contains 30 tablets (3 blister packs with 10 tablets per pack).

*These statements have not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.**Source: Signum’s R&D Experimental Biology ConferenceThe information on this page is for product training in the United States based on country-specific regulatory compliance.

EHT Brain Formula

Supplement FactsServing Size: 1 Tablet

Amount Per Serving % Daily Value

Vitamin D (as cholecalciferol)Vitamin B6 (as pyridoxine HCl) 1.6 mg

2,000 IU 500%80%

167%4%

100%

***

10 mcg16 mg

50 mcg

*Daily value not established.

50 mg35 mg

70 mcg

Vitamin B12 (as methylcobalamin)Magnesium (from 100 mg magnesium citrate)

Other ingredients: Dicalcium phosphate, microcrystalline cellulose, coating (polyvinyl alcohol, titanium dioxide [color], macrogol, vanillin, talc), stearic acid, croscarmellose sodium, magnesium stearate and silica. DECAFFEINATED.

Selenium (as selenomethionine)

Huperzine-A (from Huperzia serrata whole plant extract)Alpha lipoic acidEHT® (proprietary coffee extract)

®




Youth Factor enzyme blend A proprietary enzyme blend that helps support optimal bioavailability of antioxidants and polyphenols, so your body receives the full benefits of these ingredients.

Complex NAATM An antioxidant-rich blend that offers immune support, and brighter, healthier-looking skin.

PrimaVie® Shilajit Mineral-rich properties that have been used for thousands of years in Ayurveda. It’s known to support antioxidant- and energy- related functions in the body. Additionally, PrimaVie is known to boost mitochondrial energy synthesis, an essential biological process for healthy aging.

Pyrroloquinoline quinone (PQQ)

A micronutrient, found naturally in many green leaves and legumes, which works as an antioxidant and energy producer in the body. It is considered an essential ingredient to support mitochondrial energy.

Coenzyme Q-10 A natural antioxidant synthesized in the body that supports oxygen and energy production. It’s found in fruits, vegetables and grains.

Niacin Also known as vitamin B3, this ingredient is known to support cellular energy production and cardiovascular health.

APPROPRIATE FOR: Men and women 18 years of age or older.

WHEN AND HOW DO I USE IT?As a dietary supplement, take one tablet daily with food. Take with Youth Factor™ Superfood & Antioxidant Boost Powder for synergistic benefits.

PRODUCT FEATURES:• Bottle contains 30 supplements.• Includes 100% daily value of Pantothenic acid, also known as vitamin B5, which

records indicate may help support cellular energy production in the body.• Includes a proprietary blend of goji berry, Korean mint and fig, which help

reduce the appearance of wrinkles and reveal brighter-looking skin.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

* Daily value not established.Other ingredients: Microcrystalline cellulose, vegetable stearic acid, croscarmellose sodium, organic film coating (maltodextrin, sunflower lecithin, palm olein and guar gum), vegetable magnesium stearate and silica.

Supplement FactsServing Size: 1 Tablet

Amount PerServing

% DailyValue

20 mg 100%

Pantothenic acid (as D-calcium pantothenate)

10 mg 100%

Calcium 130 mg 13%

255 mgProprietary Cellular Energy Blend:Coenzyme Q10, Shilajit extract, Quercetin dihydrate, Polygonum cuspidatum root extract (min. 50% resveratrol), Pterocarpus marsupium wood extract (min. 5% pterostilbene), PQQ (Pyrroloquinoline quinone)

*

*40 mgYouth FactorTM Enzyme Blend (160 IsoU) endo-1,4-beta-xylanase and endo-1,4-beta-D-glucanase

50 mgComplex NAATM Blend: Korean mint leaf (Agastache rugosa), Fig fruit (Ficus carica), Goji berry (Lycium barbarum)

*

* Daily value not established

Niacin (as flush-free inositol hexanicotinate)

Servings Per Container: 30

Youth Factor™

Complete Vitality ComplexWHAT IS IT? Youth Factor Complete Vitality Complex is a holistic daily supplement containing our patent-pending Youth Factor™ enzyme blend, a host of antioxidants and Nerium’s patent-pending Complex NAA™ blend. Its ingredients work at the cellular level to help support optimal function, maintenance and repair of your body, inside and out.*

WHAT DOES IT DO?Youth Factor Complete Vitality Complex featuring our innovative, comprehensive formula:• Supports cellular energy*• Aids in the defense of free radicals*• Supports the immune system*• Reduces the appearance of wrinkles*• Reveals brighter-looking skin*

*These statements have not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.




Youth Factor enzyme blend A proprietary enzyme blend that helps support optimal bioavailability of antioxidants and polyphenols, so your body receives the full benefits of these ingredients.

Complex NAA™ An antioxidant-rich blend that offers immune support, and brighter and healthier-looking skin.

Superfood blend Known to support healthy cellular function and help guard against free radical damage.

Palatinose Also known as Isomaltulose, it is a slow and sustained-release carbohydrate working as an energy source to keep the body and brain functioning. It is naturally present in honey and sugarcane extracts.

Resveratrol A polyphenolic compound naturally found in peanuts, grapes, red wine and some berries.

Pterostilbene A plant-sourced antioxidant found mainly in blueberries, chemically related to resveratrol.

WHAT IS IT?Youth Factor Superfood & Antioxidant Boost Powder is formulated with our patent-pending Youth Factor™ enzyme blend, exclusive Complex™ NAA blend, a pH adjuster, body-fortifying antioxidants and hearty servings of fruits and vegetables to help boost your body into its optimal state of well-being* from the inside out.*

WHAT DOES IT DO?Youth Factor Superfood & Antioxidant Boost Powder contains ingredients that:• Balance pH levels to keep your body at a more optimally alkalized and less acidic state*• Defend against free radical damage*• Increase the body’s ability to absorb the most beneficial ingredients in your supplement and food*• Reduce the appearance of wrinkles*• Reveal brighter-looking skin*

APPROPRIATE FOR: Men and women 18 years of age or older. Keep out of reach of children.

WHEN AND HOW DO I USE IT?As a dietary supplement, mix 1 packet with 8 fl. oz. of cold water, or use with foods like fruit, yogurt or ice cream. Consume within 15 minutes after opening. Use in conjunction with your Youth Factor™ Complete Vitality Complex supplement for optimal benefits.

PRODUCT FEATURES:• Box contains 30 drink powder packets.• Youth Factor Superfood & Antioxidant Boost contains as much:

◦ Thiamin as 8 servings of green peas. ◦ Riboflavin as 8 servings of mushrooms. ◦ Vitamin B6 as 4 servings of bananas. ◦ Niacin as 9 servings of avocados. ◦ Magnesium as 7 servings of red beets. ◦ Potassium as 4 servings of broccoli.

Youth Factor™

Superfood & Antioxidant Boost Powder

Other ingredients: Citric acid, guar gum, natural berry flavors, silica and rebaudioside A.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement FactsServing Size: 1 Packet (5.5 g)Servings Per Container: 30

Amount Per Serving % Daily ValueCaloriesTotal Carbohydrate 1%*

Thiamin (as thiamin HCI) 100%Riboflavin 100%Niacin 100%

100%Vitamin B12 (as methylcobalamin) 100%Biotin 100%Pantothenic acid (as D-calcium pantothenate) 100%

** Dietary Fiber *

Proprietary Superfood Blend:Beet root, pomegranate, carrot, apricot, bilberry fruitextract, European black currant, grapefruit, lemon,lime, orange, plum, red grape, tangerine, mulberry fruit, maqui berry, cranberry, red raspberry, kale leaf,strawberry, blueberry, acai fruit (Euterpe oleracea), blackberry, black raspberry, cherry, acerola fruit extract, apple, apple pectin, banana, mango, papaya, peach, pear, pineapple, tomato, watermelon

Potassium (as potassium diphosphate) 7%

†

Complex NAATM Blend: 50 mg †

* Percent Daily Values are based on a 2,000 calorie diet.** Daily value not established.

2%*

153 g

1.5 mg1.7 mg20 mg

2 mg6 mcg

300 mcg10 mg

2 g<1 g

250 mg

Sugars

Vitamin B6 (as pyridoxine HCI)

880 mg

Proprietary Antioxidant Blend:Isomaltulose, matcha tea leaf, green tea leaf extract, muscadine grape seed, pterostilbene 90% (from Ptercarpus marsupium wood extract), flax

Korean mint leaf (Agastache rugosa), Fig fruit(Ficus carica), Goji berry (Lycium barbarum)

endo-1,4-beta-xylanase and endo-1,4-beta-D-glucanase

1.63 g †

Youth FactorTM Enzyme Blend (160 IsoU) 40 mg †

Magnesium (as magnesium oxide) 13%50 mg

*These statements have not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.



Q: HAVE NERIUM’S SKINCARE PRODUCTS BEEN TESTED FOR ALLERGIC REACTIONS?

A: Yes. The products have undergone rigorous, industry-standard dermatological safety testing to assess the potential for irritation and allergy. This ensures the vast majority of users will not experience an allergic response.

Q: ARE NERIUM PRODUCTS SAFETY TESTED? A: Nerium products have undergone extensive safety testing. Testing

has been performed at accredited laboratories, following Good Laboratory Practices and industry-recognized protocols. The products are safe to use.

Q: ARE THERE OCCASIONAL DIFFERENCES IN NERIUM PRODUCTS?

A: Our products are formulated with several proprietary compounds sourced from natural plants. Even though standard extraction protocols are followed, plant extracts may exhibit slight differences throughout the year depending on the environment and time in which the actual plants are harvested. These slight differences in appearance have no impact in any way on the safety, quality or efficacy of the product.

Q: IS NERIUM NIGHT CREAM CONSIDERED A MOISTURIZER?

A: No. Our Night Cream was not specifically designed to moisturize, although there are certain ingredients in the formula that can help hydrate the skin. Our Day Cream, however, is a very effective moisturizer.

Q: CAN NERIUM PRODUCTS BE USED WITH OTHER SKINCARE PRODUCTS?

A: Yes, there should be no impact on efficacy. As a general recommendation, you may want to test a small area of skin with both products before applying them on a larger area to see if there is any reaction to the combination.

Q: CAN NERIUM PRODUCTS BE USED ON PROBLEM SKIN?

A: Nerium products are cosmetics and are not designed to treat, cure or heal medical skin conditions. If you have a skin condition and would like to try the product, first test on a small area to ensure there is no reaction and that the product is compatible with your skin.

Q: SHOULD I CHANGE THE AMOUNT OF NERIUM PRODUCTS I USE FOR DIFFERENT SEASONS OR TEMPERATURES?

A: External environmental changes can play a major role in impacting the condition of the skin. As the climate changes from winter to summer, your skin may become very dry or sunburned, requiring different amounts of Nerium products to be used to compensate for some of these transitional, more sensitive and reactive skin states.

Q: DOES NERIUM WORK ON ALL SKIN TYPES? A: Nerium products are designed to work with all skin types. However,

that does not eliminate the possibility that someone with highly reactive or sensitive skin may experience minor irritation. If you feel this may be the case for your skin, it’s best to test the product on a small area before applying it to a larger area.

Q: HOW DO I INTRODUCE NERIUM INTO MY DAILY ROUTINE?

A: Every time a new product is introduced to your daily routine, you may or may not encounter a temporary response. In some cases, your skin may need to gradually become accustomed or adapt to a product prior to long-term usage. We recommend allowing at least two to three weeks for your skin to acclimate. If you have a severe reaction, stop using any new products and seek medical advice.

Q: HOW SHOULD NERIUM PRODUCTS BE STORED? A: Due to the nature of the products, they can be impacted by

extremely hot or cold temperatures (for example: being left in the trunk of a car). As a rule, follow the storage conditions stated on the package to preserve the product’s highest quality as established by Nerium. Keep bottles at room temperature as much as possible.

Q: DO NERIUM SKINCARE PRODUCTS HAVE AN EXPIRATION DATE?

A: Currently there are no regulations or requirements in the United States to include expiration dates on cosmetic products. Nerium has established a two-year shelf life on our products; this time expectation is supported as long as the products are stored correctly. If you suspect the products have not been stored properly, please ensure the contents have not changed color, consistency or smell before applying or selling. If this is the case, do not apply or sell the products.

Q: ARE NERIUM’S WELLNESS SUPPLEMENTS AND DRINK POWDER SAFE FOR PREGNANT WOMEN TO USE?

A: As with any ingestible product, if you are pregnant or think you may be pregnant and would like to try Nerium wellness supplements or drink powders, it’s best to consult your physician before use.

Q: HOW OLD DO YOU NEED TO BE TO USE NERIUM SUPPLEMENTS OR DRINK POWDER?

A: At least 18 years old. For ages 18 and under, please consult your physician before using. Keep out of reach of children.

Q: WHAT IS THE SHELF LIFE OF NERIUM’S SUPPLEMENTS AND DRINK POWDER?

A: EHT® Brain Formula, Youth Factor™ Complete Vitality Complex and Youth Factor™ Superfood & Antioxidant Boost have a shelf life of two years.

Q: CAN I USE THE EYE PATCH IN CONJUNCTION WITH THE EYE SERUM?

A: Eye Patches can be used as a complementary product along with our Age-Defying Eye Serum for a complete age-defying eye regimen. It can also be used as a standalone product.

Q: CAN I APPLY ILLUMABOOST BRIGHTENING & SHIELD DIRECTLY TO MY SKIN?

A: Yes, IllumaBoost can be mixed with your product or applied directly to your skin. Its thin texture allows the product to immediately soak into your skin with no sticky or tacky residue.

Q: WHAT HAPPENS IF I DON’T USE THE BOTTLE OF ILLUMABOOST WITHIN 15 DAYS AFTER OPENING?

A: The product is safe to use after 15 days of opening; however, the potency of the ingredients will diminish as time goes on.

This FAQ is written with a United States perspective based on country-specific regulatory compliance.

FAQs



ALOE BARBADENSIS LEAF JUICEExtracted from the leaves of the aloe vera plant, this powerful juice contains many beneficial components including polysaccharides, which are responsible for skin’s natural ability to hydrate and retain water; glycoproteins, which play an important role in supporting the core structure of the skin matrix; and vitamins A (beta-carotene), C and E, which are potent antioxidants.

ALPHA LIPOIC ACID A naturally occurring antioxidant that helps support healthy sugar levels.

ALTEROMONAS FERMENT EXTRACT Helps shield skin from environmental stressors.

CAFFEINESmooths the appearance of dimpled skin.

CASTOR SEED OILThis plant is indigenous to the southeastern Mediterranean Basin, Eastern Africa and India. The seed contains between 40–60% oil that is rich in triglycerides. When used on dry skin, castor seed oil lubricates and helps cells stay hydrated, making it an ideal moisturizer.

CHOLECALCIFEROL (VITAMIN D)Vitamin D is vital to bone metabolism, calcium absorption and other metabolic processes in the body.

COCOA BUTTERA natural, super-moisturizing ingredient that is high in antioxidants and fatty acids.

COMPLEX NAA™A proprietary, antioxidant-rich blend that offers immune support as well as brighter and healthier-looking skin.

COCONUT-DERIVED SURFACTANTSSulfate-free surfactants that gently, but effectively, help cleanse the skin.

EHT ® A mix of bioactive molecules isolated from coffee, developed after more than 20 years of scientific research* by Dr. Jeffry Stock. His investigation suggests the EHT molecule optimizes the function of PP2A, a key protein that helps keep neuronal connections in the brain strong and healthy.*

FORSKOHLII ROOT OILA natural ingredient that helps firm skin to reduce the appearance of dimpling.

GLYCERINDerived from lipids, this skin humectant absorbs moisture and supports skin’s natural barrier.

GREEN TEAA super antioxidant containing polyphenols, which guard against environmental damage.

HUPERZINE-AKnown to enhance acetylcholine effects, the essential neurotransmitter in the brain responsible for many functions, including cognition and memory. It also protects against free radicals.

HYDROMOIST*A superior hydrator ten times more powerful than hyaluronic acid and better than collagen alone at retaining water in the skin. Helps smooth the appearance of fine lines and wrinkles.

I-FIL4R™An exclusive ingredient derived from white lily and Brazilian ginseng that helps reduce the appearance of puffiness, fine lines and dark circles.

JOJOBA ESTERSLightweight, natural moisturizer known for providing long-lasting hydration.

KOMBUCHA FERMENTA unique ingredient, derived from fermented tea, that offers a host of skin benefits.

MAGNESIUMA mineral crucial to the body’s function. Helps keep blood pressure normal, bones strong and the heart rhythm steady.

METHYLCOBALAMIN (VITAMIN B12)A water-soluble vitamin naturally present in some foods. Vitamin B12 is required for proper red blood cell formation and neurological function.

NAE-8®Our patented, propriety extract derived from nerium oleander and aloe vera acts as a powerful antioxidant that targets free radical damage and works on the top layer of skin to boost natural cell renewal.

NERIUM OLEANDERThis plant is hardy, adaptable and bears clusters of pinkish-white and red flowers in the spring time. Our exclusive and patented NAE-8 ingredient is formed from processing the nerium oleander leaf and aloe vera plant.

NIACINAMIDEA well-known ingredient used for more even-toned looking skin.

PEPTIDESPeptides, advanced peptides and peptide blends are composed of amino acids and are the building blocks of proteins. They support skin’s natural production of collagen and elastin, which is critical to fight the signs of aging.

PEPTIDE MATRIX (COLLAGEN, ELASTIN AND GLYCOSAMINOGLYCANS)Restores skin’s suppleness and firmness for a youthful, even and radiant complexion.

PHYTOLUMINAA proprietary blend of the plant ingredients alpinia officinarum root extract, physalis pubescens fruit juice and bidens pilosa, it helps skin look radiant and brighter.

PYRROLOQUINOLINE QUINONE (PQQ)Is a micronutrient, found naturally in many green leaves and legumes, which works as an antioxidant and energy producer in the body. It is considered an essential ingredient to support mitochondrial energy.

PRIMAVIE® SHILAJITUsed for its mineral-rich properties. It’s also known to support antioxidant- and energy-related functions in the body.

PYRIDOXINE HCI (VITAMIN B6)Vitamin B6 plays a role in cognitive development as well as immune function.

Key IngredientsNerium products contain many of the best age-fighting ingredients on the market. These ingredients are standouts in the fight to combat the signs of aging. Use this glossary to help you understand the incredible ingredients found in Nerium products.

*Hydromoist (Polyglutamic Acid) is a registered product of Silicones Plus.



*Source: Signum’s R&D Experimental Biology ConferenceThe Key Ingredients and Key Terms sections are written with a United States perspective. Please refer to each country’s Product Training Guide for approved language and claims. The Product Training Guide is for internal use by Nerium Brand Partners only.

ANTIOXIDANTS Antioxidants work to protect cells from free radical damage caused by environmental factors such as smog, pollution and sun exposure. Can be man-made or naturally occurring.

CELLULAR ENERGY Cellular energy is key to health; a consequence of aging is a decline in cellular energy levels. Mitochondria play an important role in the utilization of energy for metabolic function.

EMOLLIENT A substance with the ability to soften, relax and soothe the skin.

EXTRINSIC FACTORS Environmental factors, such as sun exposure, stress, inflammation, poor eating habits, pollution and smoking. Each can lead to the visible signs of aging on the skin.

FREE RADICALS An especially reactive atom or group of atoms that has one or more unpaired electrons. They can damage cells, proteins and DNA by altering their chemical structure. Antioxidants (see above) fight free radicals.

INTRINSIC FACTORS Physiological and genetic causes of aging skin, including poor circulation, reduced estrogen, diminished cell turnover, decreased collagen and decreased elastin synthesis.

OXIDATIVE STRESS Oxidative stress occurs when an imbalance exists between the production of free radicals and the body’s ability to counteract or detoxify their harmful effects with antioxidants (see antioxidants and free radicals).

PH-ADJUSTER pH-adjusters balance the acid levels in your body, helping to put it in its optimal state of being. When your body is in an alkaline state – not acidic, like most – it’s functioning at its highest level.

SUPERFOOD A nutrient-rich food considered to be especially beneficial for health and wellbeing.

SURFACTANTCleansing property that emulsifies and washes debris and oil from the skin.

In discussing anti-aging, there are many terms and phrases that are commonly referenced. The following definitions can help you better understand the science behind anti-aging.

Key Terms

RESVERATROLPart of a group called polyphenols, which act like antioxidants. Found in the skin of red grapes.

RICE BRAN OILFights free radicals to help combat the look of premature aging.

SEA3C™An exclusive blend of sea whip extract, betula platyphylla japonica juice and raffinose, which are known to moisturize the skin.

SELENIUMA mineral needed for certain enzymes that help with normal body functions.

SHEA BUTTERA superior natural moisturizing ingredient that protects skin from dryness and other environmental factors.

SIG-1191™ A patented, exclusive ingredient that works as a super antioxidant.

SODIUM HYALURONATEThe sodium salt of hyaluronic acid (HA) is a smaller molecule that can help boost and lock moisture content in the skin, resulting in smoother, softer and fuller-looking skin.

SUPEROXIDE DISMUTASEPotent antioxidant that guards against free radical damage.

TETRAHEXYLDECYL ASCORBATE (VITAMIN C)A vitamin known for its antioxidant and skin-brightening properties.

TOCOPHEROL (VITAMIN E)A potent antioxidant.

UBIQUINONE (COQ10)A vitamin-like ingredient with antioxidant properties that occurs naturally in the skin. Supports healthy collagen production.

WHITE WILLOW BARK EXTRACTKnown for its exfoliating benefits. Contains salicin, an aspirin-like structure that helps to reduce skin irritation.

YOUTH FACTOR™ ENZYME BLENDProprietary enzyme blend that helps support optimal bioavailability of antioxidants and polyphenols, so your body receives the full benefits of these ingredients.

Key Ingredients



Products at a GlanceUnited States Canada Mexico

South Korea Japan Australia Colombia Hong Kong New Zealand

Age-Defying Night Cream, NeriumAD® Formula

Age-Defying Day Cream, NeriumAD® Formula

Age-Defying Night Cream, Optimera™ Formula

Age-Defying Day Cream, Optimera™ Formula

Age-Defying Night Cream, Optimera® Plus Formula

Age-Defying Day Cream, Optimera® Plus Formula

Age-Essential Night Cream, Optimera+™ Formula

Age-Essential Day Cream, Optimera+™ Formula

Age-Defying Eye Serum

Firming Body Contour Cream, NeriumAD® Formula

Firming Body Contour Cream, Optimera™ Formula

Body Couture Cream™, Optimera™ Formula

EHT® Brain Formula*

EHT™ (Natural Health Product)*

EHT™ (Nutritional Supplement)*

Memory Formula*

Eye-V™ Moisture Boost Hydrogel Patches

Nerium Eye-V™ Moisture Boost Hydrogel Patches

Moisture Eye-V™ Boost Hydrogel Patches

Youth Factor™ Complete Vitality Complex

Youth Factor™ Superfood & Antioxidant Boost Powder

IllumaBoost™ Brightening & Shield

Double-Cleansing Botanical Face Wash


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