Prof. DR. SHAZIA ANJUM - Islamia University · Shazia Anjum 2 ♦ Ability to assess market trends...

Shazia Anjum

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Prof. DR. SHAZIA ANJUM

Department of Chemistry The Islamia University of Bahawalpur

Pakistan +92 3002525 961; +92 629239063

[email protected]; [email protected]

OBJECTIVE:

My passion is to engross myself in research, academia and to provide high quality educational

opportunities to youth of my country at an international standard. Determined to Direct, Manage,

and Coordinate the activities of the University in order to ensure that the policies, programs, goals

and objectives of the University in compliance with the University governance requirements, and

any regulations, rules, laws, codes, standards applicable to higher institutions of learning.

SUMMARY OF SPECIFIC SKILLS, KNOWLEDGE AND EXPERIENCE:

♦ An extensive 17-years hands-on experience in Synthetic Organic Chemistry/Medicinal

Chemistry/Natural Product Chemistry and proficient with structure elucidation of complex

natural products using spectrometry techniques and X-ray diffractions. Possessing 7-years

experience in designing and execution of multi-step organic syntheses of bio-molecules.

♦ Innovative in research and development, and allow integration of Synthetic Organic

Chemistry/Medicinal Chemistry/Natural Product Chemistry with other disciplines of life

sciences (e.g. Pharmacy, and Biotechnology). Author/co-author of 1 US patents and over 87

international research publications (IMPACT FACTOR: 158.725) in the area of Synthetic

Organic Chemistry/Medicinal Chemistry/Natural Product Chemistry. Recipient of two

international and several national awards.

♦ Over 9-years of research and teaching experience in the university. An amicable and

enthusiastic Chemistry Teacher with the ability to motivate students to work at optimal

levels while maintaining a comfortable, creative environment, and keeping clear perspective

of goals to be accomplished in research.

♦ Experience in organizational design/restructuring and transformation of organizational

processes; strong appreciation of emerging global trends in higher education

♦ The ability to represent the University effectively in its dealings with Government,

International agencies and other external stakeholders, a track record of success in fund

raising.

♦ Ability to take a long-term and strategic view and entertain a wide range of possibilities in

developing and implementing strategic plans.

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♦ Ability to assess market trends in Higher Education and devise a strategic direction to take

the University forward.

♦ Dependable team player, able to communicate and work well with all personnel from

technicians to scientists of all disciplines. Recognized for creativity, determination and

ability to work independently without direction. Appropriate organization, record keeping,

verbal and written communication skills.

PERSONAL QUALITIES:

♦ Possess inspirational leadership in implementing the vision and long term strategy for the

University

♦ Own strong intellectual resources and abilities

♦ Hold the confidence to delegate effectively and to encourage and empower others to achieve

their best

♦ Enjoy the strong leadership ability, people and performance management skills; keep an

ability to focus and demonstrate persistence and constancy when taking decisions, even

when circumstances are difficult and issues are controversial, a zest for finding innovative

solutions to problems, and for ensuring they are implemented with tenacity and sensitivity.

PROFESSIONAL EXPEREINCE:

1) 2011– TILL-TO-DATE DIRECTOR/PROFESSOR

[CHOLISTAN INSTITUTE OF DESERT STUDIES, ISLAMIA UNIVERSITY OF BAHAWALPUR, PAKISTAN]

♦ Teaching modern research methodologies and grant proposals writing to graduate students

and conducting laboratory sessions and discussion groups; preparing, administrating and

grading examinations, laboratory assignments and reports. Working with faculty committees

dealing with curriculum planning and degree requirements, and performing a wide variety of

administrative duties.

♦ Supervising 8 M. Phil students and conducting research in the field of phyto-medicinal

chemistry.

♦ Writing research proposals to win grants to support graduate students in research and to

transform Cholistan Institute of Desert Studies into world-class institute in the

Environmental Sciences.

♦ Presenting key scientific findings at major international conferences; conducting several

international and national conferences/workshops

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♦ Providing professional consultative services to hospitals, government, industry and private

individuals.

♦ Setting up Small Scale Herbal Pharmaceutical Hubs in Cholistan Desert to Alleviate Poverty

in the Region.

2) 2008– 2011 RESEARCH ASSOCIATE

[UNIVERSITY OF SASKATCHEWAN, DEPARTMENT OF CHEMISTRY, SASKATOON, SK S7N 5C9, CANADA]

♦ The synthesis of naturally occurring 1,1'-linked aminodisaccharide and its several analogues

produced by bacteria such as Bacillus subtilis was accomplished.

♦ Explored the biosynthetic path way for the synthesis of 1,1'-linked aminodisaccharide by

synthesizing all of its biological precursors.

♦ How bacteria synthesize 1,1'-linked aminodisaccharide is still unknown! Therefore, in vitro

kinetics experiments with purified protein have resulted interesting and exciting results that

are going to be publish in due course soon.

♦ Additionally, helped grad and undergrad students in their research projects.

3) 2006 – 2008 RESEARCH SCIENTIST: MEDICURE INC. 4-1200 WAVERLEY ST

WINNIPEG, MB R3T 0P4

CANADA. WWW.MEDICURE.COM

♦ Accomplished research to discover, develop, refine, and evaluate new cardiovascular

compounds; and submitted a patent on “New NO-Releasing Antiischemic Agents: Using a

Fluoropryidin-3-yl Phosphoric Acid Derivative as a Template”

♦ Invented a small scale synthesis of MC-1 (company’s cardiovascular drug) for ADME

studies; investigated chemical aspects of the mechanisms of drug action

♦ Solved the long standing issue regarding absolute stereochemistry of MC-5422 (company’s

cardiovascular drug) through X-ray crystallography

♦ Proposed research project and initiated research on factor VIIa/TF inhibition as a part of

antithrombotic program

♦ Participated in interdisciplinary research and development projects working with analytical

chemist, biologists, microbiologists, and other professionals

4) 2003 – 2006 ASSISTANT PROFESSOR: INTERNATIONAL CENTER FOR CHEMICAL &

BIOLOGICAL SCIENCES, HEJ RESEARCH INSTITUTE

OF CHEMISTRY KARACHI UNIVERSITY,

PAKISTAN. WWW.ICCS.EDU

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♦ Taught medicinal chemistry, natural product chemistry, and synthetic chemistry to

undergraduate and graduate students and conducted laboratory sessions and discussion

groups; prepared, administered and graded examinations, laboratory assignments and reports

Worked with faculty committees dealing with such matters as curriculum planning and

degree requirements, and performed a variety of administrative duties

♦ Supervised 4 PhD students and conducted research in field of medicinal chemistry and

natural product chemistry; and published over 71 research articles in scholarly journals

♦ Designed two research labs, one for X-ray diffraction studies and another for medicinal

chemistry for the graduate students.

♦ Won IDB (Islamic Development Bank, PSF (Pakistan Science Foundation) and HEC

(Higher Education Commission) grants to support graduates students in research

♦ Presented key scientific findings at major international conferences; conducted several

international and national conferences/workshops

♦ Provided professional consultative services to hospitals, government, industry and private

individuals

5) 2002-2003 POSTDOCTORAL FELLOW: CONSEJO SUPERIOR INVESTIGACIONES CIENTFICAS,

INSTITUTO DE QUÍMICA ORGÁNICA GENERAL,

JUAN DE LA CIERVA, 3-28006 MADRID, SPAIN.

WWW.IQOG.CSIC.ES/IQOG

♦ Accomplished research on transition metal mediated cycloisomerization of enynes: synthetic

applications to natural products

♦ Helped junior colleagues in syntheses and structure elucidation of complex compounds

4) 2000-2001 SENIOR SCIENTIFIC OFFICER: PAKISTAN COUNCIL OF SCIENTIFIC AND INDUSTRIAL

RESEARCH LABORATORIES COMPLEX, OFF

UNIVERSITY ROAD, KARACHI-75280, PAKISTAN

WWW.PCSIR.GOV.PK

♦ Isolated and characterized naturally occurring cholinesterase inhibitors

♦ Designed and synthesized novel Prolyl endopeptidase inhibitors

♦ Synthesized anti- tumor quinoxaline and benzimidazole derivatives; and established a novel

approach towards the synthesis of acridines

♦ Provided professional consultative services to private sector

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PROFESSIONAL TRAINING:

1) 2003 X-RAY CRYSTALLOGRAPHY: X-RAY CRYSTALLOGRAPHY UNIT, SCHOOL OF

PHYSICS,

UNIVERSITY SAINS MALAYSIA, 11800 USM, PENANG,

MALAYSIA; WWW.FIZIK.USM.MY/PHY2

♦ Experienced with single crystal X-ray structure determination of natural products, synthetic

compounds, organometallics and inorganic compounds

♦ Trained to fully operate XRD, from data collection to structure solution and knowledgeable

for the maintenance and trouble shooting of the instrument.

2) 1997 TISSUE CULTURE TRAINING: BIOMEDICAL AND GENETIC ENGINEERING DIVISION,

A. Q. KHAN RESEARCH LABORATORIES, ISLAMABAD,

PAKISTAN. WWW.NCB.GOV.PK

♦ Learned basic animal tissue culture, cryopreservation, DNA isolation and PCR analysis, and

karyotyping using cytoscan (chromosomal analysis)

♦ Determined cytotoxicity of natural and synthetic compounds in MTT/SRB assays

EDUCATION:

♦ PhD, Chemistry, University of Karachi (HEJ, Research Institute of Chemistry, International

Center for Chemical and Biological Sciences), Pakistan 2001

♦ MSc., Chemistry, Bahauddin Zakariya University, Multan, Pakistan 1993

AFFILIATIONS

1. Professor, Department of Chemistry, The Islamia University of Bahawalpur (IUB)

2. Adjunct Faculty, HEJ, Research Institute of Chemistry, International Center for Chemical

and Biological Sciences, University of Karachi.

3. Adjunct Faculty, NUST, Islamabad

4. Chairperson Library Committee, IUB

5. Member of Board of Advance Studies and Research, IUB

6. Member of Academic Council, IUB

7. Member of American Chemical Society

8. Member of Chemical Society of Pakistan

9. Member of Semester System Committee, IUB

10. Member of Budget Committee, IUB

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11. Member of Medical Committee, IUB

12. Member of Research Ethics Committee, IUB

13. Member of Research Ethics Committee, National University of Health Sciences

14. Member of Advisory Committee (CIDS), IUB

HONORS and AWARDS:

♦ 13th Cholistan Award 2011, Pakistan ♦ Izaz-I-Kamal, Presidential Award 2006, Pakistan

♦ Third World Academy of Sciences Young Chemist Award 2005, Italy

♦ Mohtarma Fatima Jinnah Medal in 2005, Pakistan

♦ Postdoctoral Scholarship (2002-2003) from Ministry of Culture and Education, Spain

♦ Merit Scholarships in S.S.C., H. Sc. and B. Sc. From Government of Pakistan (throughout

1st class, 1st position in the academic career).

♦ Best Girl of the College in H.SC. 1988

SKILLS:

♦ Expert in medicinal and analytical chemistry (including excellent practical skills); good

interpersonal skills; and the ability to work effectively as part of a team alongside scientists

from other disciplines; and flexible to work in a dynamic environment

♦ Able to use spreadsheet, word processing, database software and SHELXTL

♦ Fluent in English, Urdu, Hindi, and Punjabi; some familiarity with Persian, Spanish &

Arabic

COMMUNITY ACTIVITIES AND HOBBIES:

♦ Involved in fund-raising for the earthquake victims of Northern Pakistan.

♦ Mentored country girls of Pakistan to study and develop their career in Science

♦ Took initiative to organize art activities in HEJ, Research Institute of Chemistry,

International Center for Chemical and Biological Sciences), Pakistan

♦ Provided students-counseling to dealing with their personal stress and difficulties

♦ Like to play badminton, and cards, walking and driving across the countryside, studying

both Urdu and English literature; and listening pop and folk music.

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LIST OF PUBLICATIONS

1. Synthesis of an Antibacterial and Antifungal Cinnoline Derivative by Rearrangement of a β-

Carboline Derivative, Shazia Anjum, Thaira Sarfraz, Yusuf Ahmad and Atta-ur Rahman,

Heterocycles, 43(9), 1996, pp. 1887-1892. (Japan)

Impact factor: 1.077

2. Two New Pregnane-Type Steroidal Alkaloids From Sarcococca saligna, Atta-ur-Rahman,

Shazia Anjum, Afgan Farooq, M.Riaz Khan and M. Iqbal Choudhary, Phytochemistry,

46(4), 1997, pp. 771-775. (U.K.)


3. Antibacterial Sterodial Alkaloids from Sarcococca saligna, Atta-ur-Rahman, Shazia

Anjum, Afgan Farooq, M.Riaz Khan, and M. Iqbal Choudhary, J. Nat. Prod, 61, 1998, pp.

202-206. (U.S.A.)


4. Phytochemical Investigation on Steroidal Alkaloids of Sarcococca saligna, Atta-ur-Rahman,

Shazia Anjum, Afgan Farooq, M. Riaz Khan and M. Iqbal Choudhary, Nat. Prod. Lett., 11,

1998, pp. 297-304 (Switzerland)


5. Structure-Activity Relationships of Imperialine Derivative and their Anticholinergic

Activity, Atta-ur-Rahman, M. Iqbal Choudhary, Afgan Farooq, Shazia Anjum, J.Baumgold

and B. Sener, Planta Med., 64, 1998, pp.172-174 (U.S.A.)


6. Degradative and Synthetic Studies on Rapamycin- A Potent Immunosupperssant, Afgan

Farooq, Shazia Anjum, and Atta-ur-Rahman, Curr. Org. Chem., 2(3), 1998, pp. 281-328

(U.S.A)


7. Fungal Transformations of (1R, 2S, 5R)-(-)-Menthol by Cephalosporium aphidicola, Atta-

ur-Rahman, M. Iqbal Choudhary, M. Yaqoob, A. Farooq, F. Asif , and Shazia Anjum, J.

Nat. Prod, 61, 1998, pp. 1340-1342. (U.S.A.)


8. Microbial Transformations of Cytotoxic Natural Products, Atta-ur-Rahman, Afgan Farooq,

Shazia Anjum and M. Iqbal Choudhary, Curr. Org. Chem. 1999, 3, pp.309-326. (U.S.A.)

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9. New Steroidal Alkaloids from Sarcococca saligna, Atta-ur-Rahman, M.Riaz Khan, Shazia

Anjum, Afgan Farooq, and M. Iqbal Choudhary, J. Nat. Prod, 63, 2000, pp.1364-1368

(U.S.A.)


10. Preliminary Pharmacological Evaluation of Marine Organisms Collected from Collected

from Coastal Area of Karachi, Ahsana Dar, Talat Roome, Farah Rza Pour, Sharam Behnian,

Azher Sherkhli, M. Iqbal Choudhary, S. Atif Ali, Shazia Anjum, Shakil Ahmed, Farzana

Akhtar, Shamsher Ali, Atta-ur-Rahman and Kashif Pervez, Proc. Natl. ONR Symp. On

Arabian Sea as a source of Biological Diversity, 2000, p. 1.

11. Guar Meal in Poultry Feed, Shazia Anjum, M. Ali Kalhoro, Nighat Afza and S. M. Abdul

Hai, J. Chem. Soc. Pak., 2001, 23(3), p.175-177. (Pakistan)

Impact factor: 0

12. The Study of Elements in Poultry Feed, Nighat Afza, Shazia Anjum, K. Shirin, M. Ali

Kalhoro and S. M. Abdul Hai, J. Chem. Soc. Pak., 2002, 24(3), p.194-196(Pakistan)

Impact factor: 0

13. Pregnane-Type Steroidal Alkaloids of Sarcococca saligna: A New Class of Cholinesterase

Inhibitors, Atta-ur-Rahman, Zaheer-ul-Haq, Asaad Khalid, Shazia Anjum, M.Riaz Khan,

and M. Iqbal Choudhary, Hel. Chem Acta., 2002, 85, p. 678-688. (Germany)


14. Broncho-Vasodilatory Activity of Fractions and Pure Constituents Isolated from Bacopa

monniera, Shabana Chana, Ahsana Dar, Muhammad Yaqoob, Shazia Anjum, Zia Sultani,

Atta-ur-Rahman, J. Ethnopharmacology, 86, 2003, p. 27-35 (Ireland)


15. A Free Radical Approach to the Synthesis of the 1,7-Dioxaspiro[4,4]Nonane ring System

from Carbohydrate Templates, Jose Marco-Contelles, Laura Domingues, Shazia Anjum,

Paloma Ballesteros, Elena Soriano and Denis Postel: Tetrahedron Asymmetry, 2003, 14(19),

p. 2865-2869 (U. K)


16. Absolute Configuration of 14β-Hydroxy-3β-O-(L-Thevetosyl)-5β-Card-20(22)-Enolide

Chloroform Disolvate, Sarooj Cheenpracha, Suchada Chatraproma, Chatchanok Karalai,

Shazia Anjum, Kan Chantrapromma, Azhar Abdul Rahman and Hoong-Kun Fun, Acta

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Crys. E., 2003, E59, p. o1694-o1696 (U. K)

Impact factor: 0

17. 20-Dimethylamino-3α-Methylamino-5α-Preganane, M. Iqbal Choudhary, Krishina Parsad

Devekota, Shazia Anjum, Azhar Abdul Rahman, Hoong-Kun Fun and Atta-ur-Rahman,

Acta Crys. E., 2003, E59, p. o1682-o1684 (U. K)

Impact factor: 0

18. 20-Methylamino-3α-Methylamino-4,4,14-Trimethyl-5α, 9,19-Cyclopregnan, M. Iqbal

Choudhary, Shamsher Ali, Shazia Anjum, Azhar Abdul Rahman, Hoong-Kun Fun and

Atta-ur-Rahman, Acta Crys. E., 2003, E59, o1751-o1753 (U. K)

Impact factor: 0

19. 17-Ethynyl-3,17α-dimethoxy-5β-estra-1,3,5(10)-triene, M. Iqbal Choudhary, Syed Ghulam

Musharaf, Shazia Anjum, Azhar Abdul Rahman, Hoong-Kun Fun and Atta-ur-Rahman,

Acta Crys. E., 2003, E59, o1745-o1747 (U. K)

Impact factor: 0

20. 20-N-Ethyl-1,8,14-Trihydroxy-16β,18-Dimethoxylycoctoninie, Farzana Shaheen, Manzoor

Ahmad, Shazia Anjum, Azhar Abdul Rahman, Hoong-Kun Fun, M. Iqbal Choudhary and

Atta-ur-Rahman, Acta Crys. E., 2004, E60, o774-o776 (U. K)

Impact factor: 0

21. Kinetics and Structure-Activity Relationship Studies on Pregnane-type Steroidal Alkaloids

that Inhibit Cholinesterases, Asaad Khalid, Zaheer-ul-Haq, Shazia Anjum, M.Riaz Khan,

Atta-ur-Rahman, and M. Iqbal Choudhary, Bioorganic & Medicinal Chemistry, 2004, 12,

p.1995-2003 (Japan)


22. Naturally Occurring Cyclohexane Epoxides: Sources, Biological Activities and Synthesis, J.

L. Marco Contelles, M. Teresa Molina and Shazia Anjum, Chem. Rev., 2004, 104(6),

p.2857-2900 (U.S.A.)


23. 3-(3,7-dimethylocta-2,6-dienyloxy)-1,8-dihydroxy-6-methyl-9,10-anthraquinone, Nawong

Boonnak, Suchada Chatraproma, Hoong-Kun Fun, Shazia Anjum, Shamsher Ali, Atta-ur-

Rahman and Chatchanok Karalai, Acta Crys. E., 2005, E61, p. o410-o412 (U. K)

Impact factor: 0

24. Microbial Transformation of (-)-Isolongifolol and Butyrylcholinesterase Inhibitory Activity

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of Transformed Products, M. Iqbal Choudhary, Syed Ghulam Musharaf, Sarfraz ahmad

Nawaz, Shazia Anjum, Masood Pervez, Hoong-Kun Fun and Atta-ur-Rahman, Bioorganic

& Medicinal Chemistry, 2005, 13, p. 1939-1944 (U. K)


25. Microbial Transformation of Mesterolone, M. Iqbal Choudhary, Sadia Sultan, Saima Jalil,

Shazia Anjum, Azhar Abdul Rahman, Hoong-Kun Fun and Atta-ur-Rahman, Chemistry &

Biodiversity, 2005, 2, p. 392-400 (Germany)


26. PtCl2-Mediated Cycloisomerization of Unsaturated Propargylic Carboxylates, Shazia

Anjum and Marco-Contelles, Tetrahedron. 2005, 61, p. 4793-4803 (U.S.A.)


27. (E)-1-(1,3,6,8-Tetramehoxynaphthalen-2-yl)but-2en-1-one, M. Iqbal Choudhary, Alain Meli

Lannang, Shamsher Ali, Shazia Anjum and Hoong-Kun Fun, Acta Crys. E., 2005, E61, p.

o1015-o1017 (U. K)

Impact factor: 0

28. 5,7-Dihydroxy-6,2’-Dimethoxyisoflavone, Nighat Sultana, M. Iqbal Choudhary, Shamsher

Ali, Shazia Anjum, Hoong-Kun Fun and Atta-ur-Rahman, Acta Crys. E., 2005, E61, p.

o1812-o1814 (U. K)

Impact factor: 0

29. 2-(9-Hydroxy-3a,5a,5b,8,8,11a-Hexamethylicosahydro-1H-Cyclopenta-[a]cyrysen-1-

ylpropanoic acid (3β-Hydroxylupan-29-oic acid), Pakakrong Thongdeeying, Suchada

Chantrapromma, Hoong-Kun Fun, Shazia Anjum, Shamsher Ali, and Chanita

Ponglimanont, Acta Crys. E., 2005, E61, p. o1861-o1863 (U. K)

Impact factor: 0

30. 5,9,10-Trihydroxy-2,2-Dimethyl-12-(3-Methylbut-2-enyl)-2H,6H-Pyrano[3,2-b]Xanthen-6-

one Methanol Solvate, Suchada Chantrapromma, Nawong Boonnak, Hoong-Kun Fun,

Shazia Anjum and Atta-ur-Rahman, Acta Crys. E., 2005, E61, p. o2136-o2138 (U. K)

Impact factor: 0

31. 4-(4’-Hydroxy-3’-Methoxystyryl)-1-Methlpyridinium 4-Chlorobenzenesulfonate, Suchada

Chantrapromma, Boonwasana Jindawong, Hoong-Kun Fun, Shazia Anjum, and

Chatchanok Karalai, Acta Crys. E., 2005, E61, p. o2096-o2098 (U. K)

Impact factor: 0

32. Methyl[2, 4, 5-Tri-Hydroxy-6-(Hydroxymethyl)perhydropyran-3-yl]Carbamate, Shahid

Shazia Anjum

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Iqbal Awan, M. Iqbal Choudhary, Atta-ur-Rahman, Shazia Anjum, Shamsher Ali and

Hoong-Kun Fun , Acta Crys. E., 2005, E61, 02354-02356 (U. K)

Impact factor: 0

33. Absolute Configuration of (R)-Synephrine Hydrochloride, Muhammad Sajid, Shazia

Anjum, M. Iqbal Choudhary, Atta-ur-Rahman, Masood Parvez and Ietidal Eltahir

Mohammed, Acta Crys. E., 2005, E61, 02534-02536 (U. K)

Impact factor: 0

34. Bilirubin Pigments in the First Meconium of Newborn Infants, Sina Aziz, Shazia Anjum,

Atta-ur-Rahman, Durre Samin Akram, Syed Ali Anwar Naqvi and Syed Adibul Hasan Rizvi,

Journal of Pakistan Medical Association, 2005, 55(5), p. 188-192 (Pakistan)

35. N, N'-Diphenylsuccinamide, Shazia Anjum, M. Iqbal Choudhary, Shamsher Ali, Hoong-

Kun Fun and Atta-ur-Rahman, Acta Crys. E., 2005, E61, p. o3001-3002 (U. K)

Impact factor: 0

36. 1-Isopropenyl-3a,5a,5b,8,8,11a-hexamethylicosahydro-1h-cyclopenta[a]chyrsen-9-yl-4-

hydroxy-3-methoxycinnamate, Charoen Pakhathirathien, Suchada Chantrapromma, Hoong-

Kun Fun, Shazia Anjum, Atta-ur-Rahman and Chatchanok Karalai, Acta Crys. E., 2005,

E61, p. o2942-o2944 (U. K)

Impact factor: 0

37. New Diterpenoids from Stem and Roots of Caesalpinia crista, Sarot Cheenpracha, Rattikan

Srisuwan, Chatchanok Karalai, Chanita Ponglimanont, Suchada Chantrapromma, Kan

Chantrapromma, Hoong-Kun Fun, Shazia Anjum and Atta-ur-Rahman, Tetrahedron. 2005,

61, p. 8656-8662 (U.S.A.)


38. 16β,17-Dihydroxy-ent-Kauran-19-oic Acid, Nasir Rasool, Viqar Uddin Ahmad, M. Iqbal

Choudhary, Hoong-Kun Fun, Shazia Anjum and Shamsher Ali, Acta Crys. E., 2005, E61, p.

o3053-o3055 (U. K)

Impact factor: 0

39. (5R, 6S, 8S, 9R, 14R, 15R, 17R, 18S, 21S, 24R, 26S, 27R)-Chloro-16, 24-cyclo-13,14-

Secoergosta-2-ene-18,26-dioicacid-14:17,14:27-diepoxy-6,13, 20, 22-tetrahydroxy-1,15-

dioxo-γ-lactone δ-lactone methanol solvate monohydrate, Sammer Yousuf, M. Iqbal

Choudhary, Atta-ur-Rahman, Shazia Anjum, Hoong-Kun Fun and Shamsher Ali, Acta Crys.

E., 2005, E61, o3523-o3525 (U. K)

Impact factor: 0

Shazia Anjum

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40. 2-Methoxycarbonyl succinanilic acid, Shazia Anjum, M. Iqbal Choudhary, Shamsher Ali,

Hoong-Kun Fun and Atta-ur-Rahman, Acta Crys. E., 2005, E61, o3520-o3522 (U. K)

Impact factor: 0

41. 10,12,12-Tris(3,3-dimethylallyl)-6,7-Dihydroxy-2,2,9-Trimethyl-1H-pyrano[2,3-

b]anthracen-5(12H)-one, Simeon F. Kouam, Bonaventure T. Ngadjui, M. Iqbal Choudhary,

Atta-ur-Rahman, Shazia Anjum, and Shamsher Ali, Acta Crys. E., 2005, E61, o3545-o3547

(U. K)

Impact factor: 0

42. (4-Hydroxyphenyl)(9,11,13-trihydroxyphenyl)methanone mono hydrate, M. Iqbal

Choudhary, Suad Naheed, Shazia Anjum, Shama Nasim, Atta-ur-Rahman and Hoong-Kun

Fun, Acta Crys. E., 2005, E61, o3584-o3586 (U. K)

Impact factor: 0

43. Dynamic Molecular Recognition in the Generation of New Crystal Engineering Motif: A

Unique Case Study of a Dicarboxylic Acid with a Ditopic Receptor to Favor Polymeric over

Dimeric Hydrogen Bonded Supramolecular Complex, Shyamaprosad Goswami, Swapan

Dey, Hoong-Kun Fun, Shazia Anjum and Atta-ur-Rahman, Tetrahedron Letter, 2005, 46, p.

7187-7191 (U. S. A.)


44. 2,3-Dihydro-7-Hydroxy-3-[(4-Methoxyphenyl)Methylene]-4H-1-Benzopyran-4-One,

Sompong Boonsri, Suchada Chantrapromma, Hoong-Kun Fun, Chatchanok Karalai,

Akkharawit Kanjana-opas and Shazia Anjum, Acta Crys. E., 2005, E61, p. o3930-o3932

(U. K)

Impact factor: 0

45. 2-(3, 7-Dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone, M. Iqbal Choudhary,

Rasheeda Swaleh, Shazia Anjum, Hoong-Kun Fun, Alain Meli Lannang and Shamsher Ali,

Acta Crys. E., 2005, E61, p. o4313-o4315 (U. K)

Impact factor: 0

46. 4'-Hydroxy-5-methoxy-6,7-methylenedioxyisoflavone, Jeannie Bee-Jan Teh, Hoong-Kun

Fun, Ibrahim Abdul Razak, Suad Naheed, M. Iqbal Choudhary and Shazia Anjum, Acta

Crys. E., 2005, E61, p. o4310-o4312 (U. K)

Impact factor: 0

47. 1, 13-Dimethyl-6H,7H,8H-Chromeno[3’,4’:5,6]Pyrano[3,2-c]Chromene-6,8-Dione, M. Iqbal

Choudhary, Alain Meli Lannang, Shazia Anjum and Hoong-Kun Fun, David Lontsi

Shazia Anjum

13

and Jean Gustave Tangmouo, Acta Crys. E., 2006, E62, p. o116-o118 (U. K)

Impact factor: 0

48. 5-Formyl-2,3-dihydroisocoumarin, Zamarrud, Viqar Uddin Ahmad, Shazia Anjum and M.

Qaiser, Acta Crys. E., 2006, E62, p. o405-o407 (U. K)

Impact factor: 0

49. Bis(piperidine-1-dithiocarbamato-κ2 S,S')palladium(II), Farkhanda Shaheen, Amin Badshah,

Shazia Anjum and Ali Saqib, Acta Crys. E., 2006, E62, p. m329-m330 (U. K)

Impact factor: 0.

50. Anti-inflammatory activity of Bacopa monniera in rodents, Shabana Channa, Ahsana Dar,

Shazia Anjum, Muhammad Yaqoob and Atta-ur-Rahman, J. Ethnopharmacology, 104,

2006, p. 286-289 (Ireland)


51. 5-Hydroxy-4’,6, 7-Trimethoxyflavon, M. Shaiq Ali, Shamsher Ali, Shazia Anjum,

Waqar Ahmad, Acta Crys. E., 2006, E62, p. o1107-o1109 (U. K)

Impact factor: 0

52. 2,3-Dihydro-7,8-dihydroxy-3-[(4-methoxyphenyl)methylene]-4H-1-benzopyran-4-one,

Suchada Chantrapromma, Sompong Boonsri, Hoong-Kun Fun, Shazia Anjum and

Akkharawit Kanjana-opas, Acta Crys. E., 2006, E62, p. o1254-o1256 (U. K)

Impact factor: 0

53. 20(29)-Lupene-3b,28b-diacetate, Ietidal Eltahir Mohamed, M. Iqbal Choudhary, Shamsher

Ali, Shazia Anjum and Atta-ur-Rahman, Acta Cryst. E., 2006, E62, o1352–o1354 (U. K)

Impact factor: 0

54. 14-Acetyl-20-ethyl-1,8-dihydroxy-16,18-dimethoxylycoctonine, Manzoor Ahmad,

Shamsher Ali, Farzana Shaheen, Shazia Anjum and M. Iqbal Choudhary, Acta Cryst. E.,

2006, E62, o1428–o1430 (U. K)

Impact factor: 0

55. New α-Glucosidase Inhibitors and Antibacterial Compounds from Myrtus Communis L.,

Farzana Shaheen, Manzoor Ahmad, Shamsun Nahar Khan, Syeda Samreen Hussain, Shazia

Anjum, Bahodir Tashkhodjaev, Kambarali Turgunov, Mukhlis N. Sultankhodzhaev,

Muhammad Iqbal Choudhary and Atta-ur-Rahman, Eu. J. Org. Chem., 10, 2006, 2371-2377

(Germany)


Shazia Anjum

14

56. Norditerpenoid Alkaloids from Delphinium nordhagenii, Farzana Shaheen, Mohammad

Zeeshan, Manzoor Ahmad, Shamsun Naher, Shazia Anjum, Shamsher Ali, Hoong-Kun

Fun, Muhammad Iqbal Choudhary and Atta-ur-Rahman, J. Nat. Prod, 69, 2006, 823-825.

(U.S.A.)


57. Biotransformation of (-)-Ambrox by Cell Suspension Cultures of Actinidia deliciosa

Asma Nasib, S. Ghulam Musharraf, Sajjad Hussain, Saifulah Khan, Shazia Anjum,

Shamsher Ali, Atta-ur-Rahman and Muhammad Iqbal Choudhary, J. Nat. Prod., 2006,

69(6), 957-959. (U.S.A.)


58. Recognition of creatinine by weak aromatic acids in solid phase along with their

supramolecular network, Shyamaprosad Goswami, Subrata Jana, Anita Hazra, Hoong-Kun

Fun, Shazia Anjum and Atta-ur-Rahman, Cryst. Eng. Comm., 2006, 8, 712-‐718. (London)


59. Desmethylberginin hemihydrate, Zamarrud, Viqar Uddin Ahmad, Shazia Anjum, Faryal

Wali Mohammad and M. Qaiser, Acta Crys. E., 2006, E62, p. o4626-o4628 (U. K)

Impact factor: 0

60. Trianiliniphosphine oxide, Shazia Anjum, Atta-ur-Rahman and Hoong Kun Fun, Acta Crys.

E., 2006, E62, p. o4569-o4571 (U. K)

Impact factor: 0

61. Synthesis of Bioactive Succinylanthranilic Acid Ester and its Analogues, Abdul Majeed

Khan, Shazia Anjum, M. Iqbal Choudhary and Atta-ur-Rahman, World Journal of

Chemistry, 2006, 1 (1), 30-32 (Pakistan)

62. PtCl2- and PtCl4-Catalyzed Cycloisomerization of Polyunsaturated Precursors, José Marco-

Contelles, Nieves Arroyo, Shazia Anjum, Emily Mainetti, Nicolas Marion, Kevin Cariou,

Gilles Lemière, Virginie Mouriès, Louis Fensterbank , Max Malacria, Eu. J. Org. Chem., 20,

2006, 4618-4633 (Germany)


63. Fluoride-Water Hydrogen Bonding: X-Ray Structure of Tris(1,10-Phenanthroline) Nickel(II)

Fluoride-Ethanol(1/2) Methanol(1/2) Octahydrate, M. Arif, Z. H. Chohan, I. H. Bukhari,

Shazia Anjum and R. H.Tariq, Reviews in Inorganic Chemistry, 2006, 26(4), p. 379 -384

(Israel)


Shazia Anjum

15

64. Tris(Ethylenediamine)Nickel(II)Fluoride Dihydrate: X-Ray Structure Reveals Short

Hydrogen Bonds Between Lattice Waters and Lattice Fluorides, M. Arif, Z. H. Chohan, R.

H. Tariq, K. M. Khan and Shazia Anjum, Reviews in Inorganic Chemistry, 2006, 26(4),

385-390 (Israel)


65. Phytochemical Investigation and Biological Evaluation of Schinus terebinthifolius, Amal, M.

Youssef Moustafa, Simeon, F. Kouam, Asma Ejaz, Shamsher Ali, Shazia Anjum and

Muhammad Iqbal Choudhary, Res. J. Phytochemistry, 2007, 1(1), 1-11 (Egypt).

66. New Chemical Derivatives of the Natural Compound Dictyophlebine Inhibiting Acetyl- and

Butyrylcholinesterase, Krishna P. Devkota, M. Iqbal Choudhary, Shazia Anjum, SarfarazA.

Nawaz, Bruno N. Lenta, and Norbert Sewald, Z. Naturforsch. 2007, 62b, 1324-1328

(Germany).


67. Biotransformation of Andrenosterone by Filamentous Fungus, Cunninghamella elegans,

Muhammad I. Choudhary, Naik T. Khan, Syed G. Musharraf, Shazia Anjum, and Atta-ur-

Rahman, Steroids, 2007, 72 (14), p. 923-929 (Netherland)


68. 2-(2-Chlorobenzamido)benzoic acid, Zulfiqar Ali Khan, Khalid M. Khan and Shazia

Anjum, Acta Crys. E., 2007, E63, p. o4103-o4103 (U. K)

Impact factor: 0

69. 7-Nitro-2-phenyl-4H-3,1-benzoxazin-4-one, Zulfiqar Ali Khan, Khalid M. Khan and Shazia

Anjum, Acta Crys. E., 2007, E63, p. o4226-o4227 (U. K)

Impact factor: 0

70. Conessine isolated from Holarrhena floribunda, Alain Meli Lannang, Shazia Anjum, Jean

Gustave, Tangmouo, Karsten Krohn and M. Iqbal Choudhary, Acta Crys. E., 2007, E63, p.

o4398-o4398 (U. K)

Impact factor: 0

71. Absolute Configuration of 1β,10β-Epoxydesacetoxymatricarin Isolated from Carthamus

oxycantha, by Means of TDDFT CD Calculations, Zahid Hassan, Hidayat Hussain, Viqar

Uddin Ahmad, Shazia Anjum, M. Iqbal Choudhary, Gennaro Pescitelli, Tibor Kurtán, and

Karsten Krohn, Tetrahedron: Asymmetry, 2007, 18, p. 2905-2909 (U. K)


Shazia Anjum

16

72. Water Promoted, Microwave-Assisted Oxidative Novel Deamination of N-

Aminoquinazolinones, M. Arfan, Rasool Khan, Shazia Anjum, Shair Ahmad, M. Iqbal

Choudhary, Chinese Chemical Letters, 2008, 19, p. 161-165 (China)


73. A Benzil and Isolflavone from Iris tenuifolia, M. Iqbal Choudhary, Sumaira Hareem, Hina

Siddiqui, Shazia Anjum, Shamsher Ali, Atta-ur-Rahman and Mudassir Israr Zaidi,

Phytochemistry, 2008, 69(9), p. 1880-1885 (U.K.)


74. Synthesis and characterization of transition metal fluoride complexes with imidazole: X-ray

crystal structure reveals short hydrogen bonds between lattice water and lattice fluoride, M.

Arif, S. Nazir, M.S. Iqbal and Shazia Anjum, Inorganica Chimica Acta, 2009, 362(5), p.

1624-1628


75. Structural determination of crotamides A and B, the new amides from Croton sparsiflorus,

Rashad Mehmood; Muhammad Imran; Muhammad Safder; Shazia Anjum; Abdul Malik,

Journal of Asian Natural Products Research, 2010, 12(8), p.662-665.


76. New and Known Constituents from Iris unguicularis and Their Antoioxidant Activity, Atta-

ur-Rahman, Sumaira Hareem, Muhammad Iqbal Choudhary, Bilge Sener, Ahmed

Abbaskhan, Hina Siddiqui, Shazia Anjum, Ilkay Orhan, Ilhan Gurbuz, and Filiz Ayanoglu,

Heterocycles 2010, 82 (1), pp.813-824.


77. Synthesis and Antileishmanial and Antimicrobial Activities of Some 2,3-Disubstituted 3H-

Quinazolin-4-Ones, M. Arfan, R. Khan, M. A. Khan, Shazia Anjum, M. I. Choudhary, M.

Ahmad, J. Enzy. Inhibit. Med. Chem., 2010, 25(4), pp. 451-458. (UK)


78. A Facile Synthesis of Novel Unsymmetrical N-(4-Oxo-2-Phenyl-3(4H)-Quinazolinoyl)-N-

(Aryl)Acetamidines, M. Arfan, R. Khan, J. Mahmood, Shazia Anjum, M. I. Choudhary,

Chinese Chem. Lett., 2010, 21(8), pp. 905-910. (China)


79. Phytochemical Investigation and Biological Evaluation of Schinus terebinthifoliu, A. M. Y.

Moustafa, S. F. Kouam, A. Kulsoom, A. Ejaz, S. Ali, Shazia Anjum, M. I. Choudhary, Res.

J. Phytochem., 2010, 4(3), pp. 162-172 (Egypt)

Impact factor:

80. A Pentacyclic Triterpene from Litchi chinensis, I. Malik, V. U. Ahmad, Shazia Anjum, F.

Shazia Anjum

17

Z. Basha, Nat. Prod. Commn., 2010, 5(4), pp. 529-530


81. Duboscic acid-A Potent α-Glucosidase Inhibitor with Unprecedented Triterpenoidal Carbon

Skeleton from Duboscia macrocarpa, P. Wafo, R. S. T. Kamdem, Z. Ali, Shazia Anjum, S.

N. Khan, A. Begum, K. Krohn, B. M. Abegaz, B. T. Ngadjui, and M. I. Choudhary, Organic

letters, 2010, 12(24), pp. 5760-5763. USA


82. Kaurane-type diterpenoids from Chromoleana odorata, their X-ray diffraction studies and

potent α-glucosidase inhibition of 16-kauren-19-oic acid, P. Wafo, R. S.T. Kamdem, Z. Ali,

Shazia Anjum, A. Begum, O. O. Oluyemis, S. N. Khan, B. T. Ngadjui, X. F. Etoa and M. I.

Choudhary, Fitoterapia, 2011, 82(4), pp. 642-646.

Impact factor: 2.231 (U.K)

83. Anti-arthritic effect of GN1, a novel synthetic analog of glucosamine, in the collagen-

induced arthritis model in rats , H. Jawed, Shazia Anjum, S. I. Awan, S. U. Simjee, Inflamm.

Res., 2011, 60, pp. 1113–1120


84. Synthesis of 3,3′- Neotrehalosadiamine and Related 1,1′-Aminodisaccharides Using

Disarmed, Armed, and Superarmed Building Blocks, Shazia Anjum, Natasha D. Vetter, J.

E. Rubin, and D. R. J. Palmer, Tetrahedron. 2013, 69, p. 816-825 (U.S.A.)


85. A Previously-Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis, N. D.

Vetter, D. Langil, Shazia Anjum, J. Boisvert, R. Jagdhane, E. Omene, H. Zheng, K. van

Sttaten, D. Sanders and D. R. J. Palmer, J. Am. Chem. Soc. 2013, 135 (16), p. 5970–5973

(U.S.A.) Highlighted in JACS Spotlights link


86. The structure of NtdA, a sugar aminotransferase involved in the kanosamine biosynthetic

pathway in Bacillus subtilis, reveals a new sub-class of aminotransferases, K. E. van

Straaten, J. B. Ko, R. Jagdhane, Shazia Anjum, D. R. J. Palmer, and D. A. R. Sanders, J.

Biol. Chem., 2013, 288, 34121-34130 [First Published on October 4, 2013,

doi:10.1074/jbc.M113.500637] (U.S.A.)

Impact factor: 4.65

87. The Anti-Arthritic and Immune-Modulatory Effects of NHAG, A Novel Glucosamine

Analogue in Adjuvant Induced Arthritis, Syed Uzair A. Shah, H. Jawed, S. I. Awan, Shazia

Shazia Anjum

18

Anjum, S. U. Simjee, BioMed Research International, 2013

[http://dx.doi.org/10.1155/2013/487610] (U.S.A.)


88. Flora of Cholistan Desert, H. M. Wariss, S. A. Pirzada, K. Alam, Shazia Anjum, G. R.

Bhati and M. Mukhtar, American Journal of Plant Sciences, 2013, 4, 58-65. (U.S.A.)


89. Comparative Study of Arid and Semi-Arid Areas of Pakistan for Alternative and

Complimentary Medicines, S. Malik, S. A. Pirzada, A. Sadiq, K. Alaam, H. M. Waris, I.

Ahmad, M. Q. Hayat, Shazia Anjum, and M. Mukhtar, BioMed Research International,

2013 [Submitted]


90. Flora of Lal Suhanra National Park, Bahawalpur, Punjab, Pakistan, H. M. Wariss, S. A.

Pirzada, K. Alam, Shazia Anjum, R. Qureshi and M. Mukhtar, Acta Botanica Gallica, 2013

[Submitted]


91. Investigating Hitherto Unreported Phytomedicinal Properties of Farsetia hamiltonii Royle,

Shazia Anjum, S. Sarwar, K. Zia, N. Ghaffar, Q. Jabeen, M. Q. Hayat, Faiz-ul-Hassan

Nasim, S. Hanif, A. Sadiqa, S. A. Pirzada, K. Alam and M. Mukhtar, J. Ethnopharmacology,

2014 [submitted]


TOTAL IMPACT FACTOR: 158.725 CHAPTERS IN BOOKS: 1. Synthesis of Bioactive Natural Products by Propargylic Carboxylic Ester Rearrangements, in

Studies in Natural Products, Shazia Anjum, Elena Soriano, and J. L.M Contelles, Elsevier

Science Publishers – Amsterdam, Vol. 40, 2013, p. 51-67. (Netherlands)

LIST OF PATENTS:

1. Shazia Anjum, M. Saleem, N. Afza, M.A. Kalhoro and S. M. A. Hai, Production of

"Medicinally Important Diosgenin" from Dioscorea bulbifera available in Pakistan,

513/2001, SI No 137729, Government of Pakistan Karachi Office.

Shazia Anjum

19

2. Shazia Anjum, Atta-ur-Rahman, M. Iqbal Choudhary, F. Shaheen, M. Ahmad, S.

Nahar Khan: New α-glucosidase inhibitors and antibacterial compounds from Myrtus

communis L. 2008, US Patent, US20080269510, USA.

PAPERS PRESENTED IN NATIONAL/INTERNATIONAL CONFERENCES 1. A Previously-Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis, 1st

International Conference on Applied Chemical, Biological and Agriculture Sciences,

Government College University of Faisalabad (2014).

2. Green Chemistry and Atom Economy: A Journey Towards Metal Catalysis to Biocatalysis,

International Conference of Biochemical and Chemical Sciences, Agriculture University of

Faisalabad (2014).

3. A Story Behind Discerning Kanosamine Biosynthesis in Bacillus subtilis, 14th Asian

Symposium on Medicinal Plants, Spices And Other Natural Products, International Center for

Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi

(2013).

4. New NO-Releasing Antiischemic Agents: Using Pyridoxine as a Template, 4th International

Conference on Drug Development and Drug Therapy, Dubai, (2012).

5. Synthesis of 3,3’- Neotrehalosadiamine, an Unusual Disaccharide with Reported Antibiotic

Properties, Western Canadian Medicinal Chemistry Conference, University of Saskatchewan,

(2010).

6. PtCl2-Promoted Cycloisomerization of Polyunsaturated Precursors, 10th International

Symposium on Natural Product Chemistry, International Center for Chemical Sciences, H. E. J.

Research Institute of Chemistry, University of Karachi, Karachi (2006).

7. PtCl2-Mediated Cycloisomerization of Polyunsaturated Precursors: The Rautenstrauch

Isomerization Revisited, 9th International Symposium on Natural Product Chemistry,

International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University

of Karachi, Karachi (2004).

8. Platinum Catalyzed Cycloisomeriation of Enynes: Synthetic Applications to Medicinally

Important Natural Products, 11th Asian Symposium on Medicinal Plants, Spices and other

Natural Products, Kunming, China (2003).

9. Structure Activity Relationship Study of a Naturally Occurring Embelin and it Derivatives,

Against Prolyl Endopeptidase, 7th Eurasia Conference on Chemical Sciences (EuAsC2S- 7),



Shazia Anjum

20

10. Exciting New Discoveries of Cholinesterase Inhibitors Studies from a Pakistani Medicinal Plant,

2nd International and 12th National Chemistry Conference, University of Sindh, Jamshoro,

Pakistan, (2002).

11. Structure activity Relationship studies of a Naturally Occuring Benzoquinone, Embeline,

Against Prolyl Endopeptidase, 2nd International and 12th National Chemistry Conference,

University of Sindh, Jamshoro, Pakistan, (2002).

12. Synthesis and Rearrangement of Quinoxaline Derivative, Fareeda Ferooz, Shazia Anjum, Atta-

ur-Rahman, Tahira Sarfraz and M. I. Choudhary, 2nd International and 12th National Chemistry

Conference, University of Sindh, Jamshoro, Pakistan, (2002).

13. Interesting SAR Studies of Pregnane Alkaloids Isolated from Genus Sarcococca Against

Cholinesterase Enzymes, 8th International Symposium on Natural Product Chemistry,



14. A Novel Synthetic Approach Towards Acridine Synthesis: An Intercalating Agent, 7th

International Symposium on Natural Product Chemistry, International Center for Chemical

Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi, (1999).

15. Some Enzyme Inhibiting Natural Products From Medicinal Plants, 7th International Symposium

on Natural Product Chemistry, H. E. J. Research Institute of Chemistry, University of Karachi,

Karachi, (1999).

16. New Antibacterial Pregnane-Type Alkaloids from Genus Sarcococca saligna 7th International

Symposium on Natural Product Chemistry, International Center for Chemical Sciences, H. E. J.

Research Institute of Chemistry, University of Karachi, Karachi (1998).

17. Phytochemical Investigation of New Pregnane-Type Alkaloids from Genus Sarcococca saligna,

Sixth International Symposium on Natural Product Chemistry, International Center for Chemical

Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi (1996).

18. Synthesis of an Antibacterial and Antifungal Cinnoline Derivative by Rearrangement of a b-

Carboline Derivative, Fifth International, Symposium and Pakistan-US Binational Workshop on

Natural Product Chemistry, International Center for Chemical Sciences, H. E. J. Research

Institute of Chemistry, University of Karachi, Karachi (1994).

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