PROGRAM BOOK
CONFERENCE TOPICS
• Synapse formation and neurotransmitter receptors
• Synaptic architecture
• Intracellular trafficking and protein dynamics
• Pre- and post-synaptic function
• Synaptic plasticity and memory
• Neuronal circuits in the healthy and diseased brain
• Molecular mechanisms of neuropsychiatric disorders
2
WELCOME MESSAGE
Dear Colleagues,It is with great pleasure that we welcome you in Coimbra to participate in
the 7th ISN Special Neurochemistry Conference on SYNAPTIC FUNCTION AND DYSFUNCTION IN BRAIN DISEASES. The conference will be a dynamic and informal forum for scientific exchange and a unique opportunity to discuss and share ideas about the mechanisms that govern synapse formation, neurotransmitter release, post-synaptic receptor trafficking, synaptic plasticity, neuronal circuits and cognition and behavior. These topics will also be considered in the scope of their relevance for mech-anisms of neurodevelopmental and neurodegenerative disorders.
The program will provide multiple opportunities for interaction, during the poster ses-sions, lunch time, coffee breaks and social events. This unique setting, held at the novel Convention Center of Coimbra, which combines history and the best of the Portuguese architecture, will certainly contribute to shape your future research. We hope that the meeting will also help you finding new partners to address novel and exciting questions.
The generous support of ISN and IBRO allows the participation of young scientists from around the globe. The organizers are also grateful to all other sponsors that con-tributed to the meeting.
We invite you to discover Coimbra, a city that offers a combination of unique tra-ditions, UNESCO World Heritage Sights and a vibrant and often flamboyant student community. We wish you all an exciting and scientifically rewarding meeting!
The Organizing Committee
COIMBRAJune 1-4
&
ISN 2016
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PROGRAM AT A GLANCE
16:30 Welcomesession17:00 FoundationsofNeurochemistry inPortugal17:30 Opening Keynote presentation –RichardHuganir18:30 Welcomecocktail
Wednesday | June 1, 2016 Auditorium
9:00-12:40 | S01 Synapse formation and function
9:00 Keynotepresentation–DanielChoquet10:00 Coffeebreak(Auditoriumfoyer)10:30 Invitedtalksandselected oralcommunications
12:10 Lunch(Conventualroom)13:30 Posterpresentation (Aeminiumroom–floor1)16:00 Coffeebreak(Auditoriumfoyer)
16:30-18:00 | S02 Neurodevelopmental disorders
16:30 Invitedtalksandselected oralcommunications
Thursday | June 2, 2016 Auditorium
9:00-12:40 | S03 Synaptic plasticity
9:00 Keynotepresentation –CasperHoogenraad10:00 Coffeebreak(Cloister)10:30 Invitedtalksandselected oralcommunications
12:50 Lunch(Conventualroom)14:00 Posterpresentation (Aeminiumroom–floor1)16:00 Coffeebreak(Cloister)
16:30-18:30 | S04 Plasticity mechanisms in synaptic function and dysfunction
16:30 Invitedtalks17:30 Keynotepresentation–AlcinoSilva
18:30 Wineandcheesecocktailandcultural event(Cloister)
Friday | June 3, 2016 Mondego room – floor 2
9:00-12:40 | S05 From synapses to circuits
9:00 Keynotepresentation–RuiCosta10:00 Coffeebreak(Auditoriumfoyer)10:30 Invitedtalksandselected oralcommunications
12:40 Lunch(Conventualroom)
14:15-17:30 | S06 Circuit dysfunction and neuropsychiatric disorders
14:15 Invitedtalksandselected oralcommunications15:55 Coffeebreak(Auditoriumfoyer)16:30 Keynotepresentation–GuopingFeng
17:30 Closingremarks
Saturday | June 4, 2016Auditorium
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PROGRAM
16:30-17:00 Welcome session
17:00-17:30 Foundations of Neurochemistry in Portugal ArsélioP.CarvalhoandCatarinaR.Oliveira
K00-01 Opening Keynote Presentation | Chair:RalfDringen17:30-18:30
18:30 Welcome cocktail (Cloister)
Wednesday, June 1, 2016 | Auditorium
K01-01 Keynote | Synapse formation and function | Chair:CliveBramham09:00-10:00 Linking AMPA receptor nanoscale organization and function at excitatory synapses DanielChoquet|InterdisciplinaryInstituteforNeuroScience,France
10:00-10:30 Coffee break (Foyer)
S01 Synapse formation and function | Chair:CliveBramhamandPauloPinheiro10:30-12:40
S01-01 Building neuronal circuits after synapse degeneration: 10:30-11:00 a role for Wnts in Alzheimer’s disease PatriciaSalinas|UniversityCollegeLondon,UnitedKingdom
Thursday, June 2, 2016 | Auditorium
Regulation of neurotransmitter receptor function and synaptic plasticity in the brainRichardHuganir|JohnsHopkinsUniversitySchoolofMedicine,USA
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PROGRAM
S01-02 11:00-11:30S01-03 11:30-11:50
S01-04 11:50-12:10
12:10-13:30 Lunch (Conventualroom)
13:30-16:00 Poster presentation -Oddnumberposters(Aeminiumroom-floor1)
16:00-16:30 Coffee break (Auditoriumfoyer)
S02 Neurodevelopmental disorders | Chair:AlcinoSilvaandJoséEsteban16:30-18:10
S02-0116:30-16:50
S02-02 16:50-17:10
S02-03 17:10-17:40S02-04 17:40-18:10
Synaptotagmin-1: functional interaction with SNAREs and PI(4,5)P2JakobSørensen|UniversityofCopenhagen,DenmarkSelected oral communication - Fluorescent false neurotransmitter reveals functionally silent dopamine boutons in the striatumDanielaPereira|ChampalimaudCenterfortheUnknown,PortugalSelected oral communication - Neddylation drives spine development, synapse stability, and regulates learning and memory AnnetteVogl|MPIofPsychiatry,Germany
Selected oral communication - Thalamic reticular dysfunction underlies attention deficits and hyperactivity in the Ptchd1 knockout mouseMichaelWells|BroadInstituteofMITandHarvard,USASelected oral communication - Reduced inhibition and excitation underlies circuit-wide changes in vivo in a mouse model of Rett Syndrome AbhishekBanerjee|UniversityofZurich,SwitzerlandCharacterization of Shank proteins in the mouse brain TobiasBoeckers|UlmUniversity,GermanyProblematic proteostasis in fragile X syndromeEmilyOsterweil|UniversityofEdinburgh,UnitedKingdom
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PROGRAM
K03-01 Keynote | Synaptic plasticity | Chair:RichardHuganir09:00-10:00 Transport mechanisms underlying the biology and diseases of the nervous system CasperHoogenraad|UtrechtUniversity,Netherlands
10:00-10:30 Coffee break (Cloister)
S03 Synaptic plasticity | Chair:RichardHuganirandRamiroAlmeida10:30-12:50
S03-0110:30-11:00 S03-02 11:00-11:30
S03-03 11:30-12:00
S03-04 12:00-12:30 S03-05 12:30-12:50
12:50-14:00 Lunch (Conventualroom)
14:00-16:00 Poster presentation -Evennumberposters(Aeminiumroom-floor1)
16:00-16:30 Coffee break (Cloister)
Friday, June 3, 2016 | Mondego room (floor 2)
Synaptic signaling for plasticity during aging and Alzheimer’s diseaseJoséEsteban|CentrodeBiologiaMolecularSeveroOchoa,SpainCell adhesion contactin-associated proteins mediate homeostatic experience-dependent synaptic plasticityAnaLuísaCarvalho|UniversityofCoimbra,PortugalSelf-activating CaMKII/TIAM1 complex converts transient Ca2+ riseinto persistent biochemical signaling during LTPYasunoriHayashi|RIKEN,JapanThe Arc of synaptic memoryCliveBramham|UniversityofBergen,NorwaySelected oral communication - Structural plasticity of dendritic spines during long-term depression in a mouse model of Fragile XMiquelBosch|InstituteforBioengineeringofCatalonia,Spain
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PROGRAM
K05-01 Keynote | From synapses to circuits | Chair:GuopingFeng09:00-10:00 Generating and shaping novel action repertoires RuiCosta|ChampalimaudFoundation,Portugal
10:00-10:30 Coffee break (Foyer)
S05 From synapses to circuits | Chair:GuopingFengandEmíliaDuarte10:30-12:40
S05-0110:30-11:00
S05-02 11:00-11:30
Saturday, June 4, 2016 | Auditorium
S04 Plasticity mechanisms in synaptic function and dysfunction16:30-17:30 Chair:YasunoriHayashiandAnaSebastião
S04-01 16:30-17:00 S04-02 17:00-17:30
K04-01 Keynote | Plasticity mechanisms in synaptic function and dysfunction | Chair:RuiCosta17:30-18:30 Molecular, cellular, and circuit mechanisms that link memories across time AlcinoSilva|UCLA,USA
18:30 Wine and cheese cocktail (Cloister)
IGF-1 receptor: From synaptic transmission to Alzheimer’s degenerationInnaSlutsky|TelAvivUniversity,IsraelDysregulation of GABAergic synapses in brain ischemia: multiple mechanisms contributing to neuronal demiseCarlosDuarte|CenterforNeurocienceandCellBiology,Portugal
Modulation of GABAergic inhibitory inputs to hippocampal interneurons by adenosine AnaSebastião|UniversityofLisbon,PortugalUnderstanding the roles of prefrontal long-range connections through targeted optogenetic perturbationOferYizhar|WeizmannInstitute,Israel
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PROGRAM
S05-03 11:30-12:00 S05-04 12:00-12:20 S05-05 12:20-12:40
12:40-14:15 Lunch(Conventualroom)
S06 Circuit dysfunction and neuropsychiatric disorders | Chair: RuiCostaandJoãoPeça14:15-16:00
S06-01 14:15-14:35
S06-02 14:35-14:55
S06-03 14:55-15:25S06-0415:25-15:55
16:00-16:30 Coffee break (Foyer)
K06-01 Keynote | Circuit dysfunction and neuropsychiatric disorders Chair:CatarinaR.Oliveira16:30-17:30 Dissecting synaptic and circuitry mechanisms of autism GuopingFeng|McGovernInstituteforBrainResearch,USA
17:30 Closing remarks
Selected oral communication - A role for the parvalbumin interneuron-enriched microRNA miR-206 in schizophrenia-related behaviorsMaryHeyer|IcahnSchoolofMedicineatMountSinai,USASelected oral communication - Rett-like severe encephalopathy caused by a de novo GRIN2B missense mutation is attenuated by D-Serine dietary supplementXavierAltafaj|IDIBELL,SpainSHANK3 controls maturation of social reward circuits in the VTACamillaBellone|UniversityofLausanne,SwitzerlandRole of adenosine A2A receptors in the control of mood-related neuropsychiatric diseasesRodrigoCunha|UniversityofCoimbra,Portugal
Function of neuronal microcircuits in adult human neocortexHuibMansvelder|VUUniversityAmsterdam,NetherlandsSelected oral communication - A golden pair of synaptic adhesion molecules, netrin-G1 and netrin-G2QiZhang|RIKEN,JapanSelected oral communication - Homeostatic control of dopamine by astrocytes in the postnatal maturation of the prefrontal cortexPaolaBezzi|UniversityofLausanne,Switzerland
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COIMBRAJune 1-4
&
ISN 2016
10
FLOOR PLANS
Floor 0
Floor -1
Entrance
Regist
ratio
n an
d
Info
rmat
ion
Desk
Speakers Slide Room
Auditorium
WC
Foyer
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FLOOR PLANS
WC
Mondego Room
Floor 2
WC
Posters and ExhibitionAeminium Room
Cloister
Floor 1
Conventual Room(lunches)
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POSTER PRESENTATIONS
Poster Presentation SessionsThursdayandFriday:14:00-16:00Thursday, June 2: Oddnumberposters(e.g.PS01-01,PS01-03,PS02-01)Friday, June 3: Evennumberposters(e.g.PS01-02,PS01-04,PS02-02)
PS01 Synapse formation and function
PS01-01 Piccolo is a regulator of endosomeformationandmembranetraffickingFraukeAckermann|DZNE,Germany
PS01-02 UncoveringthemolecularmechanismsthatregulatesynapticdiversityNunoApóstolo|VIB,Belgium
PS01-03 BACE1physiological function inhip-pocampalmossyfibercircuitrySoraiaBarao|VIB,Belgium
PS01-04Nanoscale organization of synapticadhesionproteinsusing3-nmprobesIngridChamma-IINS,France
PS01-05Three mechanisms cut short trans-mission of single impulses in cholinergic syn-apses:FunctionalandpathologicalsignificanceYvesDunant|UniversityofGeneva,Switzerland
PS01-06 PresynapticroleforthesmallGTPaseArf6AnnaFassio|IstitutoItalianodiTecnologia,Italy
PS01-07 Co-agonists tune GluN2B-NMDA re-ceptor trafficking at developing hippocampalsynapsesJoanaFerreira|IINS-InterdisciplinaryInstituteforNeuroScience,France
PS01-08 Sema4D-induced stabilizationof in-hibitorypresynapticboutonsthroughactinde-polymerizationCátiaFrias|UtrechtUniversity,Netherlands
PS01-09 Apossible roleof14-3-3proteins inregulatingthedynamicsoftyrosinehydroxylasephosphorylationatmultiplesitesSadafGhorbani|K.G.JebsenCentreforNeu-ropsychiatricDisorders,Norway
PS01-10Theproteasomecontrolspresynapticdifferentiationthroughmodulationofanon-sitepoolofpolyubiquitinatedconjugatesMaria Guimarães Pinto | Center for Neurosci-enceandCellBiology,Portugal
PS01-11 Neuroplastinsarerequiredforlearningandmemory,E/Ibalance,andformcomplexeswiththePlasmaMembraneCalciumATPaseRodrigo Herrera-Molina | Leibniz Institute forNeurobiology(LIN),Germany
PS01-12 Lack of Bassoon or Piccolo differ-ently affects presynaptic voltage-dependentcalciumchannelsJuliaKlueva|LeibnizInstituteforNeurobiology,Germany
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POSTER PRESENTATIONS
PS01-13 Presynapticdifferentiationtriggeredbytarget-derivedcue ismediatedby localproteinsynthesisJoanaPedro|CenterforNeuroscienceandCellBiology,Portugal
PS01-14Fluorescent falseneurotransmitter re-vealsfunctionallysilentdopamineboutonsinthestriatumDanielaPereira|ChampalimaudCenterfortheUnknown,Portugal
PS01-15 Doc2B interacts with Munc13 andSNAREsandactsasanupstreamcalciumsen-sorforvesicleprimingPaulo Pinheiro | Center for Neuroscience andCellBiology(CNC),Portugal
PS01-16Conformational states of kainate re-ceptorsinfluencethereceptorlateralmobilityatglutamatergicsynapsesAlice Polenghi | Fondazione Istituto Italiano diTecnologia,Italy
PS01-17SorCS1 controls axonal targeting ofNeurexin-1alphaLuisRibeiro|VIBCenterfortheBiologyofDis-ease,Belgium
PS01-18 FGF22regulatessynaptogenesisandaxonbranchingbyactivatingdifferentsignalingpathwaysSusanaSampaio|CentrforNeuroscienceandCellBiology,Portugal
PS01-19The Role of ARHGAP8, a NovelRhoGAP,inGlutamatergicSynapsesJeannette Schmidt | Center for NeuroscienceandCellBiology(CNC),Portugal
PS01-20Synaptic scaffold protein BassoonregulatespresynapticautophagyKatharinaSchneider|GermanCenterforNeu-rodegenerativeDiseases(DZNE),Germany
PS01-21 CaMKIIβislocalizedindendriticspinesas both drebrin-dependent and drebrin-inde-pendentpoolsTomoaki Shirao | Gunma University GraduateSchoolofMedicine,Japan
PS01-22 Activity-regulated microRNA regu-latesGluA2expressionandexcitatory/inhibitorysynapticbalanceinthehippocampusMariline Silva | Center for Neuroscience andCellBiology(CNC),Portugal
PS01-23Removing an epigenetic brake pad,PRMT8, to accelerate the maturity of mousevisualcorticalcircuitryJudy Sng | National University of Singapore,Singapore
PS01-24 Epidermal growth factor downregu-lates presynaptic maturation and suppressessynapseformationinvitroandinvivoNobuyuki Takei | Brain Research Institute,Japan
PS01-25 Neddylationdrivesspinedevelopment,synapse stability, and regulates learning andmemoryAnnetteVogl|MPIofPsychiatry,Germany
PS01-26 Cysteine893ofGluA1 isa targetofregulatorythiolmodificationsLottaVon Ossowski | University of Helsinki,Finland
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POSTER PRESENTATIONS
PS02 Neurodevelopmental disorders
PS02-01 Effect of ginger on cerebral cortexsynaptosomal ectonucleotidases and acetyl-cholinesteraseactivitiesinhypertensiveratsAyodele Akinyemi | Afe Babalola University,Nigeria
PS02-03 TheroleofStargazininschizophreniaandIntellectualdisabilityGladysCaldeira|CenterforNeuroscienceandCellBiologyofCoimbra(CNC),Portugal
PS02-04 Identification of Deubiquitinating En-zymesthatRegulateSHANK3StabilityMeghanCampbell|Genentech,USA
PS02-05GABAergic transmission may be re-latedtotheimpairmentoflearningandmemorycausedbyprenatalsystemichypoxia-ischemiaMartaCristinadaCunhaRodrigues|Universi-dadedoEstadodoRiodeJaneiro,Brazil
PS02-06Changesinpyramidalneuronsofthesensorimotorcortexandneurobehaviorofkao-lin-inducedneonatalhydrocephalicmiceOmowumiFemi-Akinlosotu|UniversityofIbadan,Nigeria
PS02-07 Sexualdivergenceinactivity-depend-entneuroprotectiveprotein(ADNP):thebrainisnotthesameIllanaGozes|TelAvivUniversity,Israel
PS02-08Cerebellar Shank2 regulates excita-torysynapsedensityandmotor,repetitive,andanxiety-likebehaviorsSeungminHa|KoreaAdvancedInstituteofSci-enceandTechnology,SouthKorea
PS02-09 De novo mutations in DENR disruptneuronaldevelopmentandlinkneurologicaldis-orderstodefectivemRNAtranslationre-initiationJulian Heng |The Harry Perkins Institute ofMedicalResearch,Australia
PS02-10EffectofcombinedadministrationofescitalopramandrisperidoneondopamineandserotoninincreaseintheratfrontalcortexKatarzynaKamińska|InstituteofPharmacologyofthePolishAcademyofSciences,Poland
PS02-11Histone methylation by the KleefstraSyndrome protein EHMT1 mediates homeo-staticsynapticscalingNael Nadif Kasri | Donders Institute for BrainCognitionandBehaviour,Netherlands
PS02-12 Roleofcaspase-3inregulationofne-prilysinandsynapticplasticityafterhypoxiaNataliaNalivaeva|UniversityofLeeds,UnitedKingdom
PS02-13 Cannabinoidreceptor1blockadeal-leviatesthecognitivedeficitinDownsyndromemousemodelsAlbaNavarro|PompeuFabraUniversity,Spain
PS02-14 Onsetandreversionofautism-associatedsymptomsinmutantbeta-neurexin-1mousemodelEstefaniaRoblesLanuza | InstitutodeBiome-dicinadeSevilla IBiS-HUVR/CSIC/UniversidaddeSevilla,Spain
PS02-15Adenosine A2A receptors controlaxonformationduringneuronaldevelopment:implicationstoneuronalmigrationandepilep-togenesisRicardoRodrigues|CNC-CenterforNeurosci-enceandCellBiology,Portugal
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POSTER PRESENTATIONS
PS02-16Thalamic reticular dysfunction un-derlies attention deficits and hyperactivity inthePtchd1knockoutmouseMichaelWells|BroadInstituteofMITandHar-vard,USA
PS03 Synaptic plasticity
PS03-01Protein synthesis inhibitors exacer-batethedeteriorationinducedbyKClonLTPduringearlyeventsfollowinginduction:apro-poseAbdulKarimAbbas|InstituteofNeuroscienceandPhysiology,Sweden
PS03-02Neuronal membrane glycoproteinGpm6a induces filopodium formation in neur-itesthroughaCoronin-1a/Rac1/Pak1pathwayAnabelAlvarezJuliá|InstituteforResearchinBiotechnology,Argentine
PS03-03 ARMS/Kidins220 protein controlsregulatedsecretionofBDNFJuanCarlosArévalo|UniversityofSalamanca,Spain
PS03-04 Membrane-tethered AKT regulatesearlyphaseLTPexpressionviamodulationofpost-synapticAMPAreceptorsNatalyaBorovok|Tel-AvivUniversity,Israel
PS03-05Structuralplasticityofdendriticspinesduringlong-termdepressioninamousemodelofFragileXMiquel Bosch | Institute for Bioengineering ofCatalonia,Spain
PS03-06 Constitutiveactivityoftheghrelinre-ceptorcontrolshippocampalAMPARssynapticinsertionandmemoryMário Carvalho | Center for Neuroscience andCellBiology(CNC),Portugal
PS03-07 Desensitisation of rapid cholinergicneurosecretionintheTorpedomarmorataelec-tricorganJ.MiguelCordeiro|UniversityofPorto,Portugal
PS03-08 TheimpactofadenosineA1receptoroncannabinoidreceptor1-inducedmodulationofsynapticplasticityArmandoCruz|InstitutodeMedicinaMolecular,Portugal
PS03-09 BDNF upregulates synaptic expres-sionofGluN2B-containingNMDARinculturedhippocampalneuronPasqualinoDeLuca|CNC-CenterforNeurosci-enceandCellBiology,Portugal
PS03-10 Positioning of AMPA receptor-con-taining endosomes regulates synapse archi-tectureMarta Esteves da Silva | Utrecht University,Netherlands
PS03-11 Contactin-associated proteins 1 and2(Caspr1&Caspr2)-unexpectedkeyplayersintheregulationofhomeostaticsynapticscalingDominiqueFernandes|CNC-CentreforNeuro-scienceandCellBiology,Portugal
PS03-12 AninterplaybetweenCaspr1andtheRNA-bindingproteinZBP1intheregulationofhomeostaticsynapticscalingDominiqueFernandes|CNC-CentreforNeu-roscienceandCellBiology,Portugal
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POSTER PRESENTATIONS
PS03-13Adenosine A2A receptor controlslong-term potentiation in rodent and humancorticalareasSamiraFerreira |Center forNeuroscienceandCellBiology,Portugal
PS03-14 Dyrk1a,anovelregulatorofnmdare-ceptors: implications for down syndrome andalzheimer’sdiseaseMacarenaGomezdeSalazar|IDIBELL,Spain
PS03-15 In the pursuit of the fear engram:IdentificationofneuronalcircuitsunderlyingthetreatmentofanxietydisorderOssamaKhalaf|EPFL,Switzerland
PS03-16 Chronic methiopropamine increasesthespinedensityintheratnucleusaccumbensJeong-HoonKim|YonseiUniversityCollegeofMedicine,SouthKorea
PS03-17 Comparisonofthesynapticplasticityestablishedbytwogeneticallydifferentpopula-tionsofhiPScell-derivedexcitatoryneuronsThorstenLau|CentralInstituteofMentalHealth,Germany
PS03-18The RNA-binding protein hnRNP-Kacts downstream of BDNF-TrkB signaling toregulatemRNAmetabolismindendritesGracianoLeal |CNC-Center forNeuroscienceandCellBiology,Portugal
PS03-19 Role of DOR in neuronal plasticitychangespromotedbyfood-seekingbehaviourSamanthaMancino|BostonUniversitySchoolof Medicine (Boston) - Universidad PompeuFabra(Barcelona),USA
PS03-20 The Impact of Phospholipase D2GeneticAblationinAdultMouseHippocampalSynapticFunctioningLuísa Marinha | Life and Health Science Re-searchInstitute(ICVS),Portugal
PS03-21Fingolimod, a sphingosine-1-phos-phatereceptormodulator,altersNMDArecep-torpropertiesinrathippocampalslicesGuyMassicotte|UniversitéduQuébec,Canada
PS03-22 In quest for finding the key regula-torsofthemolecularmechanismsoflong-termmemoryIzhakMichaelevski|TelAvivUniversity,Israel
PS03-23 Contactin-associated protein 1 inter-actswithmetabotropicglutamatereceptortype5andmodulatesitsfunctioninthehippocampusXavierMoratóArús|UniversitatdeBarcelona,Spain
PS03-24 Controlled proteolysys of the extra-cellular matrix of the brain facilitates homeo-staticplasticityAlessandraPellerito|LeibnizInstituteofNeuro-biology,Germany
PS03-25RoleofBassoon&Piccolointhereg-ulationofvoltage-gatedcalciumchannelsatthereleasesitesandofsynapticvesiclescycleEnekoPina|LeibnizInstituteforNeurobiology,Germany
PS03-26 Coordinated synaptic plasticity atdendriticinhibitoryandexcitatorysynapsesTizianaRavasenga|FondazioneIstitutoItalianodiTecnologia,Italy
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POSTER PRESENTATIONS
PS03-27 DissectionoftheroleoftheRal/exo-cystpathwayinpostsynapticgrowthCátiaRodrigues |CEDOC-ChronicDiseasesFCM-UNL,Portugal
PS03-28Dissectionofthemechanismofexo-somereleaseattheDrosophilaNeuromuscularJunctionJoanaRodrigues|CEDOC-ChronicDiseasesFCM-UNL,Portugal
PS03-29 Matrix metalloproteinase-9 (MMP-9)activitymightprominentlyregulatepresynapticreleaseprobabilityAhmad Salamian | Nencki Institute of Experi-mentalBiology,Poland
PS03-30 thc administration affects structuralplasticityinthehippocampusVictòria Salgado | Universitat Pompeu Fabra,Spain
PS03-31 Teaching old dog new tricks: repur-posingvalproicacidasanepigeneticregulatortorewiringcorticalconnectionsandplasticityJudy Sng | National University of Singapore,Singapore
PS03-32 AstrocytephagocyticactivityregulatessynapticpruningintheadolescentbrainJeromeStaal|FloreyInstituteofNeuroscienceandMentalHealth,Australia
PS03-33 Neuronal adenosine A2A receptoroverexpression leads to NMDAR overactiva-tionandashiftinLTDinCA1/CA3hippocampalsynapsesMarianaTemido-Ferreira|InstitutodeMedicinaMolecular,Portugal
PS04 Plasticity mechanisms in synaptic function and dysfunction
PS04-01 Axonaltransportandsubcellularlocali-zationofα-synucleininDrosophilaphotoreceptorsYolandaAfonso|InstitutodeTecnologiaQuímicaeBiológica(ITQB-UNL),Portugal
PS04-02 Roleofastrocytesinhippocampalsyn-apticplasticityunderconditionsofAlzheimer´sdiseasePaulaAgostinho|FacultyofMedicine,Portugal
PS04-03 TheAlzheimer’sriskfactorsBin1andCD2AP polarize the endocytic generation ofß-amyloidClaudiaAlmeida|CEDOC-NovaMedicalSchool-UniversityLisbon,Portugal
PS04-04 NeuronalandglialNCX3asmoleculartargetinneurodegenerativedisordersLucioAnnunziato|UniversityofNaplesFedericoII,Italy
PS04-05Electrophysiological study of hip-pocampalneuronsinthemodelofAlzheimer’sdisease and neuroprotective impact of vipervenomNairaAyvazyan|OrbeliInstituteofPhysiology,Armenia
PS04-06 P2X7 receptor overexpression in theneocortex of drug-resistant human epilepticpatientsmayfavorGABAergicrundownAurora Barros-Barbosa | Instituto de CiênciasBiomédicas Abel Salazar - Universidade doPorto,Portugal
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POSTER PRESENTATIONS
PS04-07 Upregulation of the adenosine A2AreceptorandCD73inhippocampalastrocytesofpatientswithmesial temporal lobeepilepsy(MTLE)Aurora Barros-Barbosa | Instituto de CiênciasBiomédicas Abel Salazar - Universidade doPorto,Portugal
PS04-08First evidence for the recruitment ofautophagyinhumanbrainafterstrokePhilipBeart|UniversityofMelbourne,Australia
PS04-09 VitaminDsignallingandhippocampalfunctioninadultmiceThomasBurne|TheUniversityofQueensland,Australia
PS04-10 HowisagingalteringAPPtrafficking,beta-amyloidaccumulationandsynapticfunc-tion?Tatiana Burrinha | CEDOC - Chronic DiseaseResearchCenter,Portugal
PS04-11 SynapticmodulationofTaupathologypropagationSaraCalafate|VIB,Belgium
PS04-12 Deletion of the type-1 interferon re-ceptorinAPPSWE/PS1ΔE9micepreservescog-nitivefunctionandaltersmicroglialphenotypePeterCrack|TheUniversityofMelbourne,Australia
PS04-13 BACE1/AβPPinteractionatearlystag-es of Alzheimer’s disease associate with bio-physicalalterationsinlipidraftsMarioDiaz|UniversidaddeLaLaguna,Spain
PS04-14 Menopausealterssignalosomeinter-actionsinhumancorticallipidrafts.MarioDiaz|UniversidaddeLaLaguna,Spain
PS04-15 GABAtransmissionviaATP-depend-entK+channelsregulatesα-synucleinsecretioninmousestriatumEvangeliaEmmanouilidou|BRFAA,Greece
PS04-16Hyperglycemiaimpairsdendriticarbo-rizationandsynapticpunctaofnewly-generatedhippocampalneuronsinAlzheimer’sdiseaseElisabeteFerreiro|CenterforNeuroscienceandCellBiology,Portugal
PS04-17 Assessing neuroprotective effects of(poly)phenolmetabolitesinaParkinson’sdisease3DcellmodelInêsFigueira|ITQB-UNL,Portugal
PS04-18 Amyloid Beta/ APP Signalling com-plexanditseffectsatCA3synapsesSamuelFrere|TelAvivUniversity,Israel
PS04-19 Neurotoxic effects of 5-MeO-DIPTgivenchronicallyinadolescenceintheratbrainKrystynaGołembiowska | InstituteofPharma-cologyPolishAcademyofSciences,Poland
PS04-20Neurexin-Neuroligin in Alzheimer’sdisease.GenerationofaknockinmousemodelfortheframeshiftmutationNeuroligin-1T271fsFrancisco Gomez-Scholl | Instituto de Biome-dicinadeSevilla(IBiS),Spain
PS04-21Synapse dysfunction of layer V py-ramidal neurons precedes neurodegenerationinamousemodelofTDP-43proteinopathiesEmilyHandley|UniversityofTasmania,Australia
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POSTER PRESENTATIONS
PS04-22 CrosstalkbetweenCalciumandROSin the synaptic dysfunction triggered by amy-loid-betapeptideoligomersCeciliaHidalgo|F.Medicine,Chile
PS04-23 FTY720 limitsAβneurotoxicityby fa-voringsynapticversusextrasynapticNMDAre-ceptorfunctionalityinhippocampalneuronsPoojaJoshi|IRCCSHumanitas,Italy
PS04-24ATP-derived adenosine controls Aβ-inducedimpairmentofbehaviourandsynapticplasticityJoãoPedroLopes|CenterforNeuroscienceandCellBiology-UniversityofCoimbra,Portugal
PS04-25 Alterationsinpro-andanti-inflamma-toryproteinsalongincreasedpresenceofHSV-1inAlzheimer’sdiseasebrainMariaLopezdeCeballos|CajalInstituteCSIC,Spain
PS04-26TheeffectsofmiR-196aonneuronalmorphologyinvitroandinvivoSuhanMao |NationalChengKungUniversity,Taiwan
PS04-27The IRE1-XBP1 branch of the UPRdelaysamyloidbetaaccumulationandneuro-toxicityinDrosophilaCNS;implicationsinADMaría Marcora | Fundacion Instituto Leloir,Argentina
PS04-28 Mesenchymal stromal cells se-cretome-inducedaxonaloutgrowthismediatedbyBDNFLuisMartins|CenterforNeuroscienceandCellBiology(CNC),Portugal
PS04-29 Alteration of GABAA Receptor traf-fickinginstatusepilepticusMirandaMele | CNC-Center forNeuroscienceandCellBiology,Portugal
PS04-30 Dopaminergicneurotransmissiondys-function induced by ß-amyloid transforms cor-ticalLTPtoLTDandproducesmemory impair-mentPerla Moreno Castilla | Instituto de FisiologiaCelular,Mexico
PS04-31RoleofSrckinaseinoligomericamy-loid-beta-inducedearlyoxidativestressinma-turehippocampalneurons-alinktoAlzheimer’sSandraMota|CenterforNeuroscienceandCellBiology,Portugal
PS04-32Age-dependentoxidativestressinpr-esynapticterminalsofamousemodelofHun-tington’sdiseaseSandraMota|CenterforNeuroscienceandCellBiology,Portugal
PS04-33 Synaptic distribution of APP andsecretasesinmouseandhumanbraincortex-AnnaPliássova |CNC.IBILI-CNC-Center forNeuroscience and Cell Biology & Faculty ofMedicine,Portugal
PS04-34 Role of neuron-oligodendroglial cellsynapsesinmyelinationMarionPorte|BrainandSpineInstitute,France
PS04-35 SynapticplasticityinducedbyCDK5RNAiinnormalanddysfunctionalsynapsesRafaelPosadaDuque|UniversityofAntioquia,Colombia
20
POSTER PRESENTATIONS
PS04-36 Increased APP intracellular domainlevelsinadultCA1neuronsalterNMDArecep-torfunctionandassociatedmemoryprocessingPaulaPousinha|CNRSUMR7275,France
PS04-37 AMPA-receptorsubunitGluA3makessynapsessusceptibletoamyloid-ßNielsReinders|NIN,Netherlands
PS04-38 BACE1 inhibitor rescues thedynam-icsoftheaxonaldystrophiesanddecreasestheplaquegrowthrateEva Rodrigues | German Center for Neurode-generativeDiseases(DZNE),Germany
PS04-39 Blood Glutamate Scavenging as aNovelTherapeuticTreatmentforALSAngelaRuban|TelAvivUniversity,Israel
PS04-40Brainischemia-inducedalterationsintheubiquitin-proteasomesystem:roleinneu-ronaldemiseIvanSalazar |CNC-Center forNeuroscienceandCellBiology,Portugal
PS04-41 AnoxidativemechanismofcholinergicdysfunctioninneuronsexposedtoAlzheimer’s-linkedAß-oligomersLuisSantos|UFRJ,Brasil
PS04-42 Histonedeacetylaseinhibitorattenu-atesamyloidbetatoxicityinneuronsYukoSekino |National InstituteofHealthSci-ences,Japan
PS04-43 The “stressed“ autophagy: chronicstress exacerbatesTau pathology by blockingautophagyclearancesystemJoanaSilva|LifeandHealthSciencesResearchInstitute,Portugal
PS04-44 ChangesinsodiumCalciumExchanger(NCX)ExpressionAndActivityinA53tMice:NewPerspectivesinDopaminergicNeuronalDemiseAntonellaSscorziello|FedericoIIUNIVERSITYofNaples,Italy
PS04-45 Early signs of neurodegeneration indopaminergicneuronsobservedinaDrosophi-lamodelofParkinson’sdiseaseFloraStephano |UniversityofDaresSalaam,Tanzania
PS04-46Taureductionpreventscognitiveandmotor deficits in a mouse model of traumaticbraininjuryPingZheng|RoyalMelbourneHospital,Australia
PS05 From synapses to circuits
PS05-01 Homeostaticcontrolofdopaminebyastrocytes in the postnatal maturation of theprefrontalcortexPaolaBezzi|UniversityofLausanne,Switzerland
PS05-02 CharacterizationofnoveloptogenetictoolsdesignedinsilicoJoão Calmeiro | Center for Neuroscience andCellBiology,Portugal
PS05-03 Regionaldifferences inmu-opioid re-ceptor modulation of dopamine efflux in ratstriatumMariaCano-Cebrian|UniversityofValencia,Spain
PS05-04 Mechanisms underlying ribosomalregulationinaxonaldevelopmentRui O. Costa | CNC-Center for NeuroscienceandCellBiologyofCoimbra,Portugal
20 21
POSTER PRESENTATIONS
PS05-05 HCNchannelsareinvolvedinthetarhythmproductioninhippocampalformation-aninvivoandinvitrostudyPaulinaKazmierska|UniversityofLodz,Poland
PS05-06Tauproteinasakeyelementinstress-induced suppression of adult hippocampalneurogenesisIoannisSotiropoulos|LifeandHealthSciencesResearchInstitute(ICVS),Portugal
PS05-07 A golden pair of synaptic adhesionmolecules,netrin-G1andnetrin-G2QiZhang|RIKEN,Japan
PS06 Circuit dysfunction and neuropsy-chiatric disorders
PS06-01 Rett-likesevereencephalopathycausedbyadenovoGRIN2Bmissensemutationisat-tenuatedbyD-SerinedietarysupplementXavierAltafaj|IDIBELL,Spain
PS06-02 ModificationofsynapticmarkersandadenosineA1andA2Areceptordensitiesindif-ferentbrainregionsofsuicidecompletersPaulaCanas|CenterforNeuroscienceandCellBiology-UniversityofCoimbra,Portugal
PS06-03 Dimorphic,brainregion-specificreg-ulationofmicrogliabyadenosineA2ARrecep-tors:uncouplinganxietyandcognitionJoanaDuarte|CNC.IBILI,Portugal
PS06-04 GPRASP2playsaroleinmGluR1/5trafficking,modulationofneuronalmorphologyandspinematurationMohamed Edfawy | Center for NeuroscienceandcellBiology,Portugal
PS06-05 Doesearlylifeadversityaffectssocialhierarchyinadulthood?LaraFranco |CNC -Center forNeuroscienceandCellBiology;UniversityofCoimbra,Portugal
PS06-06 Selective amygdala neuronal down-regulationofadenosineA2Areceptorspreventsmood-relatedmodificationsNélioGonçalves|CenterforNeuroscienceandCellBiology,Portugal
PS06-07A role for the parvalbumin interneu-ron-enrichedmicroRNAmiR-206inschizophre-nia-relatedbehaviorsMaryHeyer|IcahnSchoolofMedicineatMountSinai,USA
PS06-08 The New Stimulant Designer Com-poundPentedroneInducesRewardingProper-tiesandAffectsDopaminergicActivityJiYoung Hwang | Sungkyunkwan University,KoreaSouth
PS06-09 BuphedroneHasRewardingResponsethroughtheDopaminergicSystemKyunginKim|SungkyunkwanUniversity,KoreaSouth
PS06-10 Leptininthenucleusaccumbensreg-ulatescocaine-inducedlocomotoractivityJungWonLee|CollegeofMedicine,KoreaSouth
PS06-11 ITGB3inneurologicaldisorders:fromthesynapsetotherapeuticopportunitiesEduardoMorais | Istituto ItalianodiTecnologia(IIT),Italy
22
POSTER PRESENTATIONS
PS06-12 P2X7 receptors drive spine synapseplasticityinthelearnedhelplessnessmodelofdepressionLillaOtrokocsi|InstitutionofExperimentalMed-icine,Hungary
PS06-13 TheImportinofAnxietyNicolasPanayotis |Weizmann InstituteofSci-ence,Israel
PS06-14 Understanding the basis of orthos-tericandallostericmodulationatGABAA-Rsinthehuntofnovelnon-sedatinganxiolyticagentsPavanPayghan|CSIR-IndianInstituteofChem-icalBiology,India
PS06-15 DimorphicresponsestochronicA2ARblockadeinamodelofdevelopmentalanxietyHelenaPinheiro|CNC.IBILI,Portugal
PS06-16 CP 47,497 and its derivatives, syn-theticcannabinoids, induceconditionedplacepreferenceandself-administrationinmiceJee-yeonSeo|SungkyunkwanUniversity,KoreaSouth
PS06-17 Enhanced adenosine A1 receptor ex-pression in forebrain neurons promotes antide-pressanteffectsandmodulatessynapticplasticityTsvetanSerchov|UniversityHospitalFreiburg,Germany
PS06-18 Homer1ainductioninthemedialPFCmediatestheantidepressanteffectsof imipra-mine,ketamineandsleepdeprivationTsvetanSerchov|UniversityHospitalFreiburg,Germany
PS06-19 AdenosineA2Areceptorsintheamyg-dalacontrolsynapticplasticityandfearmemoryAnaSimões|CenterforNeuroscienceandCellBiology-UniversityofCoimbra,Portugal
PS06-20 Tauproteinisessentialforstress-drivendepressivepathologyandcognitiveimpairmentIoannisSotiropoulos|LifeandHealthSciencesResearchInstitute(ICVS),Portugal
22
24
24 25
TRAVEL AWARDS
Abhishek BanerjeeAhmad SalamianAnabel Alvarez JuliáArmando CruzAurora Barros-BarbosaAyodele AkinyemiDaniela PereiraDominique FernandesElisabete FerreiroEmily HandleyEneko PinaEvangelia EmmanouilidouFlora StephanoJoana FerreiraJoana SilvaLuis SantosLuisa Santa MarinhaMacarena Gomez de SalazarMaria MarcoraMariana Temido-FerreiraMarion PorteMariline SilvaMarta Esteves da SilvaMary HeyerMichael WellsNicolas PanayotisOssama KhalafPaula CanasPaula PousinhaPaulina KazmierskaPavan PayghanPing ZhengPooja JoshiRafael Posada DuqueSamantha MancinoSandra MotaSara CalafateSeungmin HaSoraia BarãoTsvetan Serchov
Congratulations to the following young investigators for the ISN, IBRO and SPNtravel awards:
SwitzerlandPolandArgentinaPortugalPortugalNigeriaPortugalPortugalPortugalAustraliaGermanyGreeceTanzaniaFrancePortugalBrazilPortugalSpainArgentinaPortugalFrancePortugalThe NetherlandsUSAUSAIsraelSwitzerlandPortugalFrancePolandIndiaAustraliaItalyColombiaUSAPortugalBelgiumSouth KoreaBelgiumGermany
COIMBRAJune 1-4
&
ISN 2016
26
GENERAL INFORMATIONCoimbraCityofStudentsandaUNESCOWorldHeritageSite,Coimbraisuniqueinitsgreathis-torical legacy.CoimbrawasthebirthplaceofsixPortuguesekingsandishomeofthefirstuniversityofPortugal.Withover725yearsofhistory,theUniversityofCoimbraisoneoftheoldestinEurope.Duringyourstay,makesureyoudonotmisstheopportunitytosavourlocalgastronomy,andvisitmonumentsandhistoricaltreasures.
Conference VenueConventoSãoFrancisco,CentrodeConvençõeseEspaçoCulturalAv.daGuardaInglesa3,3040-270Coimbra
Congress SecretariatISNandRegionalMeetingSecretariatISNAdministrativeOfficec/oKenesInternationalOrganizersofCongressesS.A7,rueFrançois-Versonnex|C.P.6053|1211Geneva6,SwitzerlandT.:(+44)229069151Email:[email protected]
Ground Services & Housing Bureau MundiconveniusAvenida5deOutubro,53-2|1050-048Lisboa,PortugalT.:(+351)213155135Email:[email protected]
Registration and Information DesksTheRegistrationandInformationDesksarelocatedattheentrancefoyeroftheConventodeSãoFranciscoandwillremainopenthroughouttheConferenceduringthefollowinghours:
Wednesday,June1:15h00–18h30Thursday,June2:08h30–18h30Friday,June3:08h30–18h30Saturday,June4:08h30–18h00
Wireless internetFreeWi-Fiinternetwillbeavailableexceptintheauditorium.Nopasswordisrequired.Network:CSFConvidados
26 27
Lost and foundAlostandfoundservicewillbeavailableattheRegistrationDesk.
Name badgeEachregistereddelegatewillreceiveanamebadge.DelegatesmustwearthebadgeatalltimesduringtheConference.AdmissiontotheConferencerooms,exhibition,posters,andsocialeventsarelimitedtothosewearingthenamebadge.
Certification of attendance ACertificateofattendancewillbesentbye-mailaftertheConference.
Speaker Ready Room AllspeakersshouldgototheSpeakerReadyRoom(nexttotheRegistrationDesk)toup-loadtheirslidesatleast4hoursbeforethepresentation.Astaffpersonwillhelpspeakersuploadtheirslidesandotherfiles.
ComputerinthepresentationroomwillruninMicrosoftWindowswithPowerPoint.VGAconnec-torsforMaccomputerswillnotbeavailable.Maccomputerswillnotbeusedandpresentationswillneedtobetransferred.Theuseofpersonallaptopsforpresentationwillnotbepossible.
Speaker Ready Room ScheduleWednesday,June1:15h00–18h30Thursday,June2:08h30–16h30Friday,June3:08h30–16h30Saturday,June4:08h30–16h00
Opening Session TheOpeningSessionandthefirstlecturewilltakeplaceonWednesday,June1at16h30,attheauditorium(floor-1),andisfollowedbyaWelcomeCocktailattheCloister.
Coffee-Break Coffee-breakwillbeservedatthefoyerinfrontoftheauditoriumexceptonJune3whenitwillbeservedatthecloisters(floor1)
LunchLunchesonJune2,3and4willbeservedattheConventualroom(floor1)
Wine and Cheese Cocktail and Cultural EventWecountonyourpresenceatthewineandcheesecocktailonFriday3atthevenuecloister.ItwillbeanexcellentopportunitytoenjoythetraditionalCoimbraFado.
28
AUTHOR INDEX
Abbas,A.PS03-01Ackermann,F.PS01-01Adrian,M.PS03-10Afonso,P.PS03-09Afonso,Y.PS04-01Agostinho,P.PS04-02,PS04-24,PS04-33Akinyemi,A.PS02-01Al-Amin,M.PS04-09Alcón,C.S06-02,PS06-01Alekseeva,O.PS02-12Almeida,C.PS04-03,PS04-10Almeida,L.PS06-06,PS06-19Almeida,R.PS01-10,PS01-13,PS01-18,PS03-18,PS04-28,PS05-04Altafaj, X. S06-02, PS03-14,PS06-01AlvarezJuliá,A.PS03-02Alves,N.PS06-03,PS06-15Alves,P.PS01-10,PS01-13,PS01-18,PS04-17Alçada-Morais,S.PS02-15Amaro,A.PS04-13,PS04-14Ambrósio,F.PS06-03,PS06-15Andres,B.PS02-15Annunziato,L.PS04-04,PS04-44Apóstolo,N.PS01-02Arató,K.PS03-14Armstrong,J.S06-02,PS06-01Arévalo,J.PS03-03Asensio,C.S05-05,PS05-01AttioriEssis,S.PS03-21Ayvazyan,N.PS04-05
B.Duarte,C.PS04-40Bader,M.PS06-13
Bae,Y.PS02-08Bahilo,A.PS05-03Balafas,E.PS04-15Balduci,C.PS02-05Banerjee,A.S02-02Baptista,F.PS06-03,PS06-15Barao,S.PS01-03Barattini,P.PS04-22Barberis,A.PS01-16,PS03-26,PS04-29Barletta,R.PS04-29Barnea,A.PS02-07Barradas,P.PS02-05Barros-Barbosa,A.PS04-06,PS04-07Bassi,L.PS06-11Bayés,À.S06-02,PS06-01Bear,M.S03-05,PS03-05Beart,P.PS04-08Beeg,M.PS04-23Beleza,R.PS02-15Belfiori,L.PS04-27Bellenchi,G.PS04-44Bellone,C.S06-03Belmonte,E.PS01-06Benevento,M.PS02-11Benfenati,F.PS01-06Berentsen,B.PS03-18Bermudez-Rattoni,F.PS04-30Bessa,J.PS05-06Bethus,I.PS04-36Bezzi,P.S05-05,PS05-01Bhattacharyya,D.PS06-14Biber,K.PS06-17,PS06-18Blazquez-Llorca,L.PS04-38Blizzard,C.PS04-21Bocai,N.PS04-27Bocian,R.PS05-05
Boda,E.PS04-23Boeckers,T.S02-03Borges,S.PS05-06Borovok,N.PS03-04,PS03-22Bosch,M.S03-05,PS03-05,S04-04Bouchet,D.PS01-07Bradford,D.PS04-09Braida,D.PS04-23Bramham,C.S03-04,PS03-18Bravo,F.PS03-20Bresser,T.PS01-08Brito,C.PS04-17Brockmann,M.S01-04,PS01-25Bruchhaus,I.PS04-45Bruns,C.PS01-01Buckley,C.PS03-11Buffo,A.PS04-23Bullido,M.PS04-25Burne,T.PS04-09Burrinha,T.PS04-03,PS04-10Busquets-Garcia,A.PS02-13Butler,C.PS01-04Bye,N.PS04-08
Caetano,L.PS06-03,PS06-15Cai,W.PS03-16Calafate,S.PS04-11Caldeira,G.PS02-03,PS05-02Caldeira,M.PS04-40Calmeiro,J.PS05-02Calvo,L.PS03-03Calí,C.S05-05,PS05-01Campbell,M.PS02-04Campos-Jurado,Y.PS05-03
28 29
AUTHOR INDEX
Canas,P.PS03-13,PS04-33,PS06-02Cancedda,L.PS05-04Cano-Cebrian,M.PS05-03Cardona-Gomez,G.PS04-35Cardoso,A.PS06-05Cardoso,R.PS03-07Carlström,M.PS03-08Carro,E.PS04-25Carvalho,A.S03-02,PS01-19,PS01-22,PS02-03,PS03-06,PS03-11,PS03-12,PS03-23,PS05-02,PS06-04Carvalho,M.PS03-06Casamassa,A.PS04-04Castaño,E.PS04-27Catarino,T.PS03-06Ceccarelli,A.PS03-12Chamma,I.PS01-04Chavushyan,V.PS04-05Chen,C.PS02-03Cho,S.PS03-10Cho,Y.PS02-08Choquet,D.K01-01,S01-04,PS01-04,PS01-25Chrysanthou-Piterou,M.PS04-15Chung,C.PS02-08Cingolani,L.PS06-11Ciruela,F.S06-02,PS03-14,PS03-23,PS06-01Clark,R.PS04-21Clement,H.PS06-18Clueva,Y.PS03-25Coelho,J.PS03-33Coleman,S.PS01-26Comprido,D.PS03-18
Conn,K.PS04-09Constanze,S.PS01-11Cordeiro,J.PS01-05,PS03-07,PS04-06,PS04-07Correia-de-Sá,P.PS04-06,PS04-07Costa,G.PS04-44Costa,J.S04-02Costa,R.K05-01,S01-03,PS01-13,PS01-14,PS04-28Costa,R.O.PS05-04Courtney,M.PS01-26Coutinho,E.PS03-11Crack,P.PS04-08,PS04-12Cruz,A.PS03-08Cunha,C.PS06-03,PS06-15Cunha,R.S06-04,PS02-15,PS03-13,PS03-23,PS04-02,PS04-24,PS04-33,PS06-02,PS06-03,PS06-06,PS06-15,PS06-19Cwetsch,A.PS05-04Cyr,M.PS03-21
DaCunhaRodrigues,M.PS02-05DaSilva,B.PS04-33Dagan,S.PS06-13Dallerac,G.S05-05,PS05-01Danielyan,M.PS04-05Dawkins,E.PS04-21DeLaLuna,S.PS03-14DeLuca,P.PS03-09DeMello,F.PS04-41DeRosa,M.PS04-32DeStrooper,B.PS01-03
DeWit,J.PS01-02,PS01-17Delgado-García,J.PS02-14Deussing,J.S01-04,PS01-25Devenish,R.PS04-08DiPaolo,G.PS03-20Diaz,M.PS04-13,PS04-14Dickson,T.PS04-21Dierssen,M.PS02-13Dioli,C.PS05-06Dirk,M.PS01-11Duarte,C.S04-02,PS03-09,PS03-18,PS04-29Duarte,J.PS06-03Dubrovskaya,N.PS02-12Dulong,J.PS01-07Dunant,Y.PS01-05,PS03-07Déglon,N.S05-05,PS05-01
EckartD.,G.PS01-11Edfawy,M.PS06-04Edwards,R.S05-05,PS05-01El-Kholy,S.PS04-45Emmanouilidou,E.PS04-15Escobar,M.PS04-30Essayan-Perez,S.S03-05,PS03-05Esteban,J.S03-01,PS03-06EstevesdaSilva,M.PS03-10Eugie,M.PS04-36
Fabelo,N.PS04-13Fadda,M.PS01-06Fainzilber,M.PS06-13Falck,J.PS01-01Fassio,A.PS01-06Fejtova,A.PS01-12,PS03-25Femi-Akinlosotu,O.PS02-06
30
AUTHOR INDEX
Feng,G.K06-01,S02-01,S06-01,PS02-16,PS06-07Fernandes,D.PS03-11,PS03-12Fernandes,J.PS01-22,PS05-02,PS06-05Fernandes,S.PS06-06Fernandez-Dueñas,V.PS03-23Ferreira,D.PS03-33Ferreira,J.PS01-07,PS01-19Ferreira,S.PS02-15,PS03-13,PS04-41,PS06-03,PS06-15Ferreirinha,F.PS04-06,PS04-07Ferreiro,E.PS04-16Ferrer,I.PS03-14,PS04-13,PS04-14Ferri,C.PS04-13,PS04-14Figueira,I.PS04-17Figueiredo-Freitas,C.PS04-41Fink,C.PS04-45Fonseca,A.PS04-06Fontes,A.PS04-16Franco,L.PS06-05Frasch,C.PS03-02Frere,S.PS04-18Frias,C.PS01-08Frischknecht,D.PS03-24Frugier,T.PS04-08Fu,Z.S02-02Fuchsova,B.PS03-02Futai,K.PS03-10Fão,L.PS04-31
G.m,P.PS04-01Gabrielli,M.PS04-23Gärtner,A.PS01-03
García-Cazorla,À.S06-02,PS06-01Gardoni,F.PS04-23Garner,C.PS01-01,PS01-20Garner,L.PS01-20Gauthereau,I.PS01-04Gazit,N.S04-01Gehr,C.PS01-01Ghazaryan,N.PS04-05Ghorbani,S.PS01-09Ghoshal,N.PS06-14Giros,B.S05-05,PS05-01Giusti,S.S01-04,PS01-25Gołembiowska,K.PS02-10,PS04-19Gobb,M.PS04-23Gomes,C.PS06-03,PS06-15Gomes,R.PS04-10GomezdeSalazar,M.PS03-14Gomez-Scholl,F.PS04-20Gomis,M.PS03-30Gomis-González,M.PS02-13González-Billault,C.PS04-35González-Martínez,C.PS04-25Gonçalves,F.PS02-15,PS04-24Gonçalves,N.PS02-15,PS04-24,PS06-06,PS06-19Gonçalves,P.PS01-05,PS03-07Goosens,K.PS06-19Gorostiza,P.PS01-16Goto,H.S05-04,PS05-07Gozes,I.PS02-07Graciarena,M.PS04-34Gräff,J.PS03-15Gratacòs-Batlle,E.S06-02,PS06-01
Grau,C.S06-02,PS03-14,PS06-01Groc,L.PS01-07Groffen,S.PS01-15Groves,N.PS04-09Gruart,A.PS02-14Guerra-Gomes,S.PS04-06GuimarãesPinto,M.PS01-10Gundelfinger,E.PS01-12,PS03-25Gundelfinger,P.PS03-24GómezdeSalazar,M.S06-02,PS06-01Górska,A.PS02-10,PS04-19
Ha,S.PS02-08Haavik,J.PS01-09HacohenKleiman,G.PS02-07Härtel,S.PS04-35Halassa,M.S02-01,PS02-16Handley,E.PS04-21Hartmann,E.PS06-13Hayashi,Y.S03-03Helm,M.S04-01Heng,J.PS02-09Henke,A.S01-03,PS01-14Henriques,S.PS06-03,PS06-15Herms,J.PS04-38Hernandez-Abad,L.PS04-14Hernández,I.PS04-20Herrera-Molina,R.PS01-11Heyer,M.S06-01,PS06-07Heyninck,K.PS03-23Hidalgo,C.PS04-22Hipólito,L.PS05-03Hoffmann,J.PS04-45Holm,J.PS03-01
30 31
AUTHOR INDEX
Hoogenraad,C.K03-01,PS01-08,PS03-10Horschitz,S.PS03-17Houy,S.PS01-15Hovens,C.PS04-46Hu,G.S01-03,PS01-14Huganir,R.K00-01Hwang,J.PS06-08,PS06-09,PS06-16
I.Flydal,M.PS01-09Inestrosa,N.PS04-35Ishikawa,M.S06-01,PS06-07Ishizuka,Y.PS04-42Israely,I.S01-03,PS01-14Itohara,S.S05-04,PS05-07
Jaenisch,R.S02-02Jaffrey,S.PS01-13Jang,C.PS06-08,PS06-09,PS06-16Jeon,N.PS01-13Jiang,T.PS04-21Jones,N.PS04-12,PS04-46Jorge-Finnigan,A.PS01-09Joshi,P.PS04-23JuanPedro,B.PS03-03Jurczak,A.PS02-10
Kaczmarek,L.PS03-29Kamińska,K.PS02-10,PS04-19Kapitein,L.PS03-10Kaster,M.PS06-19Kazmierska,P.PS05-05Keinänen,K.PS01-26Kenny,P.S06-01,PS06-07Keramioti,M.PS04-15
Kerkhofs,A.PS03-13Kessels,H.PS04-37Khalaf,O.PS03-15Kilpatrick,T.PS03-32Kim,E.PS02-08Kim,H.PS03-16Kim,J.PS02-08,PS03-16,PS06-10Kim,K.PS06-08,PS06-09,PS06-16Kim,S.PS01-20Kim,W.PS02-08,PS03-16,PS06-10Kirchhoff,F.S05-05,PS05-01Kirkwood,A.PS04-35Kittel,Ê.PS06-12Kleppe,R.PS01-09Kloukina,I.PS04-15Klueva,J.PS01-12Knafo,S.S03-01Knott,G.S05-05,PS05-01Ko,Y.PS06-08,PS06-09,PS06-16Konopacki,J.PS05-05Kowalczyk,T.PS05-05Kozlova,D.PS02-12Kreiner,G.PS04-19
L.Ferreira,I.PS04-32L.Whitt,J.PS03-11Ladépêche,L.PS01-07Lamsa,K.S05-01Langlais,V.PS01-07Lanzillo,M.PS04-16Lau,T.PS03-17Laurier-Laurin,M.PS03-21Leal,G.PS03-18Leal-Ortiz,S.PS01-20
Lee,B.PS06-08,PS06-09,PS06-16Lee,D.PS02-08Lee,H.PS03-11Lee,J.PS02-08,PS06-10Lee,S.PS06-08,PS06-08,PS06-09,PS06-09,PS06-16,PS06-16Leist,M.PS04-17Leite,M.PS03-11Lemos,C.PS04-24Letellier,M.PS01-04LiJeon,N.PS01-10Li,C.S02-02Li,L.PS01-26Lim,K.PS01-04Lino,T.PS03-03Lipka,J.PS03-10Liu,S.PS04-46Lobo,G.PS04-06,PS04-07Lopes,J.PS04-02,PS04-24Lopes,L.PS03-33LopezdeCeballos,M.PS04-25Louros,S.PS02-03Lučiunaitė,A.PS04-29Ludovico,P.PS04-43Luján,R.PS03-23Lyons,D.PS04-34López-Bendito,G.PS02-15López-Benito,S.PS03-03
M.CarvalhodaSilva,A.PS04-16Maccarone,G.S01-04,PS01-25Machado,N.PS06-06,PS06-19
32
Magara,F.S05-05,PS05-01Maldonado,R.PS02-13,PS03-19,PS03-30Malinow,R.PS04-37Mancino,S.PS03-19Mansvelder,H.S05-03,PS03-13Mao,S.PS04-26Maranga,C.PS04-32Marcello,E.PS04-23Marcora,M.PS04-27Marie,H.PS03-33,PS04-36Marin,R.PS04-13,PS04-14Marinha,L.PS03-20Marques,J.PS02-15Marques,M.PS04-43MartinGarcia,E.PS03-19Martins,H.PS05-04Martins,L.PS01-10,PS01-18,PS04-28,PS05-04Martí-Prats,L.PS05-03M.CarvalhodaSilva,A.PS04-16Martínez-Mir,A.PS02-14,PS04-20Massicotte,G.PS03-21Mastrella,G.PS04-16Mateus-Pinheiro,A.PS05-06,PS06-15Matos,C.PS04-37Matsukawa,H.S05-04,PS05-07Matteol,M.PS04-23Mazzitelli,S.PS04-23McGrath,J.PS04-09McLean,C.PS04-08Mele,M.S04-02,PS03-09,PS04-29,PS05-04
Mendes,M.PS04-07Merchant,P.S01-03,PS01-14Mesa-Herrera,F.PS04-13,PS04-14Meyer-Lindenberg,A.PS03-17Michaelevski,I.PS03-04,PS03-22,PS06-13Milne,B.PS05-02Minakaki,G.PS04-15Minter,M.PS04-12Moechars,D.PS04-11Möykkynen,T.PS01-26Molinaro,P.PS04-04Montenegro,C.PS01-12Montenegro-Venegas,C.PS03-25Moore,Z.PS04-12Morais,E.PS03-18,PS06-11Morais,M.PS05-06MoratóArús,X.PS03-23Morelli,L.PS04-27Morelli,M.PS04-44Morena-Juan,V.PS02-15MorenoCastilla,P.PS04-30Mosharov,E.S01-03,PS01-14Mota,S.PS04-31,PS04-32Mothet,J.S05-05,PS01-07,PS05-01Mouska,X.PS04-36Mészáros,J.S01-03,PS01-14
Ozaita,A.PS02-13,PS03-30
P.m,D.PS04-01Panayotis,N.PS06-13Pannaccione,A.PS04-04Pao,Y.PS04-37Paoletti,P.PS01-07
Papouin,T.PS01-07Park,S.PS01-04Patil,S.PS03-18Pato,C.PS02-03Patricio,P.PS05-06,PS06-03Patrício,P.PS06-15PaulaLima,A.PS04-22Payghan,P.PS06-14Pedro,J.PS01-10,PS01-13,PS04-28,PS05-04Pellerito,A.PS03-24Pelletier,J.PS04-07Pelucchi,S.PS04-23Pen,Y.PS03-04Pereira,D.S01-03,PS01-14Peters,F.PS04-38Petrelli,F.S05-05,PS05-01Petrini,E.PS01-16,PS03-26Peça,J.PS02-03,PS03-06,PS05-02,PS06-04,PS06-05Pignataro,G.PS04-04Pina,E.PS03-25Pina-Fernandez,E.PS01-12Pinhasov,A.PS03-22Pinheiro,A.PS06-03Pinheiro,H.PS06-15Pinheiro,P.PS01-15,PS03-06,PS03-09Pinto,L.PS05-06,PS06-03,PS06-15Pinto,M.PS01-13Pinto,V.PS03-20Pitman,K.PS04-21Pliássova,A.PS04-33,PS06-02Polenghi,A.PS01-16Pollegioni,L.PS01-07Ponzoni,L.PS04-23
AUTHOR INDEX
32 33
Porte,M.PS04-34PosadaDuque,R.PS04-35Pousinha,P.PS03-33,PS04-36Prosselkov,P.S05-04,PS05-07Provencher,V.S02-02Pucci,L.S05-05,PS05-01Pépin,É.PS03-21
Queiroz,F.PS04-02Quinto-Alemany,D.PS04-13,PS04-14
Rangel,R.PS04-06,PS04-07Ravasenga,T.PS03-26Raymond,E.PS04-36Real,J.PS03-13Refojo,D.S01-04,PS01-25Rego,A.PS04-16,PS04-31,PS04-32Reichenstein,M.PS03-04Reimer,R.PS01-20Reinders,N.PS04-37Reisoli,E.PS06-11Renner,M.PS04-37ResendedeOliveira,C.PS04-33Rial,D.PS06-19Ribeiro,J.S05-01Ribeiro,L.PS01-17,PS03-06,PS03-12Rikhye,R.S02-02Rizzoli,S.S04-01RoblesLanuza,E.PS02-14Robles-Lanuza,E.PS04-20Rocha-Almeida,F.PS02-14Rodrigues,A.PS05-06,PS06-03,PS06-15Rodrigues,B.PS01-22
Rodrigues,C.PS03-27Rodrigues,E.PS04-38Rodrigues,J.PS03-28Rodrigues,M.PS02-03Rodrigues,R.PS02-15Rodrigues,S.PS04-43Rodriguez-Duran,L.PS04-30Roeder,T.PS04-45Rogóż,Z.PS02-10Rombo,D.S05-01Rosenmund,C.PS01-01Rosillo,C.PS03-26Rother,F.PS06-13Ruban,A.PS04-39Ruiz,A.PS04-20Runyan,C.S02-02Ryu,H.PS01-10,PS01-13
Sacchi,S.PS01-07Sainlos,M.PS01-04Salamian,A.PS03-29Salavessa,L.PS04-03Salazar,I.PS04-40Salgado,A.PS04-28Salgado,V.PS03-30Salinas,P.S01-01Sames,D.S01-03,PS01-14Sampaio,S.PS01-18,PS04-28SanMartin,C.PS04-22Sano,C.S05-04,PS05-07Santos,A.PS04-06,PS04-07,PS06-03,PS06-15Santos,L.PS04-41Santos,S.PS01-22,PS03-06,PS03-11,PS03-12Sardinha,V.PS06-03,PS06-15Sastre,I.PS04-25
Schätzle,P.PS03-10Schloss,P.PS03-17Schmidt,J.PS01-19Schmitt,I.S02-01,PS02-16Schmitz,Y.S01-03,PS01-14Schneider,K.PS01-20Scholl,F.PS02-14Schwarz,M.PS06-18Sebastiao,A.S05-01Sebastião,A.PS03-08Seidenbecher,D.PS03-24Seila,F.PS03-03Sekino,Y.PS01-21,PS04-42Seo,J.PS06-08,PS06-09,PS06-16Serchov,T.PS06-17,PS06-18Serra,S.PS04-28Shapira,I.S04-01,PS04-18Sheinin,A.PS03-04,PS06-13Sheng,M.S01-04,PS01-25,PS02-04Shim,K.PS06-08,PS06-09,PS06-16Shirao,T.PS01-21,PS04-42Shokunbi,M.PS02-06Shultz,S.PS04-12,PS04-46Sibarita,J.PS01-04Sierksma,A.PS01-03Silva,A.K04-01,PS04-24Silva,B.PS06-02Silva,H.PS04-24Silva,J.PS04-43Silva,M.PS01-22Simonyan,K.PS04-05Simões,A.PS06-06,PS06-06,PS06-19,PS06-19Sindreu,C.S06-02,PS06-01
AUTHOR INDEX
34
Sirabella,R.PS04-44Sisalli,M.PS04-44Slomowitz,E.S04-01Slutsky,I.S04-01,PS04-18Smalla,K.PS01-11Sng,J.PS01-23,PS03-31Soares-Cunha,C.PS04-43Sorensen,J.PS01-15Sotiropoulos,I.PS04-43,PS05-06,PS06-20Soto,D.S06-02,PS06-01Sousa,N.PS04-28,PS04-43,PS05-06,PS06-03,PS06-15,PS06-20Sousa,R.PS06-05Souza,C.PS06-06Sperlágh,B.PS06-12Sscorziello,A.PS04-44Staal,J.PS03-32Stein,V.S01-04,PS01-25Stephano,F.PS04-45Stravalaci,M.PS04-23Sullivan,R.PS04-09Sultan,S.S05-05,PS05-01Sulzer,D.S01-03,PS01-14Sur,M.S02-02Suska,A.PS03-29Sánchez-Puelles,C.S03-01Sánchez-Sanchez,J.PS03-03Sévigny,J.PS04-07Sørensen,J.S01-02
Tagliatti,E.PS01-06Takei,N.PS01-24Tanaka-Yamamoto,K.PS02-08Tang,X.S02-02Taveira,G.PS02-05Taylor,A.PS01-10
Taylor,J.PS04-08,PS04-12Teichberg,V.PS04-39Temido-Ferreira,M.PS03-33Tenorio,F.PS02-05Teodoro,R.PS03-27,PS03-28Terrasso,A.PS04-17Tessier,B.PS01-04Thalhammer,A.PS06-11Thomazeau,A.S03-05,PS03-05Thoumine,O.PS01-04Toni,N.S05-05,PS05-01Tristán-Clavijo,E.PS04-20Tsoory,M.PS06-13Turck,C.S01-04,PS01-25Turner,A.PS02-12Turner,B.PS04-21
Ubelmann,F.PS04-03Ushiki,T.PS01-24
Valero,J.PS04-16VanCalker,D.PS06-17,PS06-18VanCraenenbroeck,K.PS03-23Vasylev,D.PS02-12Vekrellis,K.PS04-15Velakoulis,D.PS04-46Vennekens,K.PS01-17Vercelli,C.S01-04,PS01-25Verderio,C.PS04-23Verhage,M.PS01-15Verstreken,P.PS04-11Vertkin,I.S04-01Vieira,R.PS04-29Vogl,A.S01-04,PS01-25VonOssowski,L.PS01-26
Watanabe,T.PS03-10Wells,M.S02-01,PS02-16Wierda,K.PS01-03,PS01-17Wierenga,C.PS01-08,PS03-10Willem,M.PS04-36Wimmer,R.S02-01,PS02-16Wright,D.PS04-46
Xavier,A.PS04-33,PS06-02Xavier,C.PS03-13Xu,X.PS02-15Xylaki,M.PS04-15
Yaguchi,K.S05-04,PS05-07Yamazaki,H.PS01-21Yang,E.PS03-32Yang,S.PS04-26Yao,A.PS01-07Yizhar,O.S05-02Yokomaku,D.PS01-24Yoo,Y.PS02-08Yoon,H.PS03-16Young,K.PS04-21
Zaragosi,L.PS04-36Zehnder,T.S05-05,PS05-01Zhang,M.PS04-12Zhang,Q.S05-04,PS05-07Zheng,P.PS04-46Zhuravin,I.PS02-12
AUTHOR INDEX
34
COIMBRAJune 1-4
&
ISN 2016
SPONSORS AND EXHIBITORSWe thank to the below sponsors and exhibitors for their valuable support to the 7th ISN Special Neurochemistry Conference
INSTITUTIONAL SPONSORS
EXHIBITORS AND SPONSORS
KEYNOTE SPEAKERS
Rui CostaChampalimaudFoundation,Lisbon,Portugal
Daniel ChoquetInterdisciplinaryInstituteforNeuroScience,Bordeaux,France
Guoping FengMcGovernInstitute,MIT,Cambridge,MA
Casper HoogenraadUtrechtUniversity,TheNetherlands
Richard L. HuganirJohnsHopkinsUniversity,Baltimore,MD
Alcino SilvaUCLA,LosAngeles,CA
