Sunday, June 03, 2018
18:00 Andreas Graner Managing Director, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany
Welcome
18:15 Fred Berger Gregor Mendel Institute, Vienna, Austria
Plenary talk: Histone variants and chromatin landscapes
19:15 Reception
Monday, June 04, 2018
Session 1: Genetic and epigene-tic influences on chromosome stability (I) Chair: Dorothy Shippen, Avraham Levy
08:30 Dorothy Shippen Texas A&M University, USA
Breaking new ground: the emer-gence of non-canonical functions for telomerase-associated subunits in Arabidopsis
09:00 Avraham Levy Weizmann Institute, Rehovot, Israel
Targeted recombination between homologous chromosomes in so-matic plant cells
09:30 Alevtina Ruban IPK Gatersleben, Germany
Tissue type-specific distribution of supernumerary B chromosomes, is it a result of programmed elimi-nation or reflection of genome in-stability?
09:45 Veronika Burešová Institute of Experimental Botany, Olomouc, Czech Republic
Spatial organization of rye chroma-tin in wheat host genome revealed by 3D-FISH
10:00 Inna Lermontova IPK, Gatersleben, Germany
Functional role of A. thaliana KNL2 in centromere assembly and geno-me stability
10:15 Sachihiro Matsunaga Tokyo University of Science, Japan
Centromere distribution by the two-step regulation through a sub-nuclear complex
10:30 Coffee Break
Session 1: Genetic and epigene-tic influences on chromosome stability (II) Chair: Julie Law, Charles White
11:00 Julie Law Salk Institute San Diego, USA
Locus-specific control of the de novo DNA methylation pathway in Arabidopsis
11:30 Dolores Córdoba-Cañero University of Cordoba, Spain
DNA damage-binding protein 2 (DDB2) regulates active DNA de-methylation mediated by ROS1 5-methylcytosine DNA glycosylase
11:45 Callie R. Kobayashi Texas A&M University, College Station, USA
NOP2 and EMC8/9: New genes involved in telomere length set point in Arabidopsis thaliana
12:00 Tony Heitkam TU Dresden, Germany
SINEs contribute to gene evoluti-on, regulation and genome rear-rangement in Solanaceae plants
12:15 Markus Kuhlmann IPK Gatersleben, Germany
EFFECTOR OF TRANSCRIPTION (ET) factors are novel plant-speci-fic regulators of genomic DNA me-thylation in Arabidopsis
12:30 Yevgeniy Shakirov Institute of Fundamental Medicine and Biol-ogy, Kazan, Russian Federation
Genomic assays in Arabidopsis thaliana identify several loci invol-ved in telomere length control
12:45 Dmitri Demidov IPK, Gatersleben, Germany
Characterization of A. thaliana mu-tants for CENH3 interacting prote-ins and plants with deregulated ex-pression of centromeric repeats as potential haploid inducers
13:00 Lunch
Session 2: Replication, cell cyc-le, DNA repair & somatic recom-bination (I) Chair: Anne Britt, Teresa Roldan-Arjona
14:00 Anne Britt University of California, Davis, USA
A wide variety of modifications of CENH3 result in haploid induction
14:30 Teresa Roldan-Arjona University of Cordoba, Spain
Base excision: at the intersection between DNA repair and epigene-tics
15:00 Ales Pecinka Institute of Experimental Botany, Olomouc, Czech Republic
SMC5/6 complex is essential for repair of zebularine-induced en-zymatic DNA-protein crosslinks in Arabidopsis
15:15 Petra Schrumpfova Prochazkova Masaryk University, Brno, Czech Republic
The plant pontin and reptin homo-logues co-localize with TERT and telomere repeat binding proteins in vivo
15:30 Ingo Schubert IPK, Gatersleben, Germany
Linking genome size and karyoty-pe evolution via DSB repair
15:45 Naoki Takahashi Nara Institute of Science and Technology, Japan
DNA damage activates two distinct signaling pathways controlling DNA repair and cell cycle arrest
16:00 Fruits and Cake
16:30 Poster presentation and subse-quent poster viewing (Session 1,2)
18:30 Joachim Schiemann Julius Kuehn Institute, Quedlinburg, Germany
Public talk: Bio und grüne Gen-technik – geht das?
19:30 BBQ & Beer
Tuesday, June 5, 2018
Session 2: Replication, cell cyc-le, DNA repair & somatic recom-bination (II) Chair: Lieven de Veylder, Holger Puchta
08:30 Lieven de Veylder VIB and University Ghent, Belgium
The importance of DNA stress checkpoint control in agriculture
09:00 Holger Puchta; Felix Wolter Karlsruhe Institute of Technology, Germany
Enhancing in planta gene targe-ting in Arabidopsis
Holger Puchta; Annika Dorn Karlsruhe Institute of Technology, Germany
The RecQ-like helicase HRQ1 is in-volved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associa-ted nuclease FAN1 and the post-replicative repair ATPase RAD5A
09:30 Eva Sykorova Institute of Biophysics, Brno, Czech Repub-lic
Telomerase interactions - from plants to human or there and back again
09:45 Petr Fajkus Institute of Biophysics, Brno, Czech Repub-lic
New insight into TERT evolution during plant speciation
10:00 Thomas Wicker University of Zurich, Switzerland
Sloppy repair of DNA damage caused by transposable elements – a major driving force of genome evolution
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10:15 Poyu Chen University of Hamburg, Germany
Isolation of novel DNA damage re-gulators based a genome-wide identification of the binding sites of the Arabidopsis Retinoblastoma homolog RBR1
10:30 Coffee Break
Session 3: Meiotic processes & recombination (I) Chair: Monica Pradillo Orellana, Peter Schlögelhofer
11:00 Monica Pradillo Orellana Universidad Complutense, Madrid, Spain
When the nucleus meets the cyto-plasm: A role for nuclear envelope-associated proteins in meiosis and DNA repair
11:30 Peter Schlögelhofer University of Vienna, Austria
Control of meiotic recombination at the rDNA
12:00 Olga Raskina University of Haifa, Israel
Genome architecture, repatterning, and diversification in Aegilops speltoides Tausch (Poaceae, Triti-ceae)
12:15 Steven Dreissig IPK, Gatersleben, Germany
Measuring meiotic recombination by sequencing of single pollen nu-clei
12:30 Guoliang Yuan Gent University, Belgium
PROTEIN PHOSHATASE 2A pro-tects sister chromatid cohesion by maintaining REC8 at the centro-meres in Arabidopsis.
12:45 David Kopecky Institute of Experimental Botany, Olomouc, Czech Republic
How to achieve genome stability in interspecific grass hybrids?
13:00 Lunch Break
Session 3: Meiotic processes & recombination (II) Chair: Ian Henderson, Stefan Heckmann
14:00 Ian Henderson University of Cambridge, UK
The Arabidopsis meiotic DSB and chromatin landscapes
14:30 Stefan Heckmann IPK, Gatersleben, Germany
Can we harness meiosis in barley?
14:45 Marie-Therese Kurzbauer Max F. Perutz Laboratories, University of Vi-enna, Austria;
AtATM limits meiotic DNA double-strand break formation and recom-bination
15:00 Cécile Raynaud Institute of Plant Sciences Paris Saclay, France
DNA polymerase epsilon plays a crucial role in the maintenance of the plant genome integrity.
15:15 Nico de Storme Ghent University, Belgium
Heat-induced defects in male mei-otic cell division and chromosome segregation
Program
15:30 Shuhei Nasuda Kyoto University, Japan
Analysis on the zygotic chromoso-me breakage induced by the ga-metocidal gene Gc2-4Ssh in wheat
15:45 Martina Dvorackova CEITEC Masaryk University, Brno, Czech Republic
Tracking the dynamics of nucleo-lar processes
16:00 Alexander Blackwell University of Cambridge, Cambridge, Uni-ted Kingdom
The role of Arabidopsis mismatch repair proteins in meiotic recombi-nation
16:15 Fruits and Cake
16:45 Poster presentation and subse-quent poster viewing (Session 3, 4)
19:00 Guided evening tour in Quedlin-burg
20:00 Conference dinner Hotel Schlossmühle Kaiser Otto Straße 28 Quedlinburg
Wednesday, June 6, 2018
Session 4: Genome enginee-ring, approaches & applications (I) Chair: Jens Boch, Götz Hensel
08:30 Jens Boch Leibniz University Hannover, Germany
Editing plant genomes for patho-gen resistance
09:00 Ayako Okuzaki Tamagawa University, Japan
Genome editing of the fatty acid desaturase 2 gene in Brassica na-pus
09:15 Niharika Sashidhar Kiel University, Germany
Genome editing strategies for mul-tiple knock out of phytic acid pa-thway genes in Brassica napus
09:30 Maartje van Kregten Leiden University, Netherlands
Genetic modification of plants re-sults from polymerase theta-media-ted end-joining
09:45 Huirong Gao DuPont Pioneer, USA
Applications of CRISPR-Cas enab-led advanced breeding technology in trait development in maize
10:00 Masaki Endo Institute of Agrobiological Sciences, NARO, Tsukuba, Japan
Genome editing in plants with en-gineered SpCas9 using NG-PAM
10:15 Michał Tomasz Kwiatek Institute of Plant Genetics of the Polish Aca-demy of Sciences, Poznan, Poland
Transfer of chromatin of wild goat-grasses (Aegilops sp.) carrying genes responsible for resistance to leaf rust into triticale (× Triticose-cale Wittmack) using chromosome engineering
10:30 Coffee Break
Session 4: Genome enginee-ring, approaches & applications (II) Chair: Sylvia de Pater, Seiichi Toki
11:00 Sylvia de Pater University of Leiden, The Netherlands
CRISPR/Cas induced mutagene-sis in Arabidopsis DNA repair mu-tants
11:30 Seiichi Toki National Agriculture and Food Research Organization, Tsukuba, Japan
New tools for plant genome engi-neering
12:00 Nathalie Durut Gregor Mendel Institute of Molecular Plant Biology, Vienna, Austria
Targeted double strand breaks in plants to study the role of chroma-tin and ncRNA during DNA repair
12:15 Goetz Hensel IPK, Gatersleben, Germany
Generation of new barley mutant alleles of LIPOXYGENASE 1 using CRISPR RNA/Cas9-endonuclease technology
12:30 Tal Dahan-Meir Weizmann Institute, Rehovot, Israel
Efficient in planta gene targeting using geminiviral replicons and the CRISPR/cas9 system
12:45 Haruyasu Hamada NARO Hokkaido Agriculture Research Cen-ter, Japan
An in planta genome editing me-thod for genetic engineering of commercial wheat
Summary and closing remarks
13:00 Barbara Hohn Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
Summarizing the meeting
13:30 Lunch and departure
Program
Support
We are looking forward to welcome you in Gatersleben.