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Progress Against Head and Neck Cancer. 1970–1979.

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Progress Against Head and Neck Cancer
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Page 1: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck

Cancer

Page 2: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1970–1979

Page 3: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1970–19791970: High-dose methotrexate therapy results in significant tumor shrinkage

Page 4: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1980–1989

Page 5: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1980–19891985: Effective, less toxic two-drug therapy is introduced

Page 6: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1980–1989Late 1980s–early 1990s: Combination chemoradiation first emerges

Page 7: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1990–1999

Page 8: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1990–19991991: Better organ preservation with initial chemotherapy and radiation

Page 9: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1990–19991992: Cigarette smoking and alcohol are conclusively linked to certain pharyngeal cancers

Page 10: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1990–19991994: Drug approved to help with saliva production

Page 11: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

1990–19991999: Chemoradiation shown conclusively to benefit patients with advanced disease

Page 12: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

2000–Present

Page 13: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

2000–Present2006: Treatment with new targeted drug cetuximab prolongs life

Page 14: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

2000–Present2007: Taxane therapy improves survival for several types of advanced head and neck cancers

Page 15: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

2000–Present2008: New research highlights role of HPV infection in head and neck

2008: Adding cetuximab to initial chemotherapy extends survival for advanced cancers

Page 16: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

2000–Present2010: HPV status and smoking affect prognosis for oropharyngeal cancer

Page 17: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

Five-Year Survival

48

53

58

63

68

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute

Page 18: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

Mortality

0

1

2

3

4

5

6

7

8

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 19: Progress Against Head and Neck Cancer. 1970–1979.

Progress Against Head and Neck Cancer

New Cases

8

9

10

11

12

13

14

15

16

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 20: Progress Against Head and Neck Cancer. 1970–1979.

Visit CancerProgress.Net for an interactive timeline of progress against a range of common cancers

CancerProgress.Net is a project of the American Society of Clinical Oncology, which represents nearly 30,000 physicians who treat people with cancer and

research new cures


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