Progress Against

Lymphoma

Progress Against Lymphoma

1970–1979

Progress Against Lymphoma

1970–19791974: FDA approves doxorubicin, a vital part of combination chemotherapy

Progress Against Lymphoma

1970–19791975: New chemotherapy regimen boosts Hodgkin lymphoma cure rates to 70 percent

1975: Era of bone marrow transplantation begins – extending lives of many patients with leukemia and lymphoma

Progress Against Lymphoma

1970–19791976: CHOP regimen boosts cure rates for non-Hodgkin lymphoma

Progress Against Lymphoma

1980–1989

Progress Against Lymphoma

1980–19891980: Imaging tests begin replacing surgery for Hodgkin lymphoma staging

Progress Against Lymphoma

1980–1989Late 1980s: Benzene established to cause blood cancers

Progress Against Lymphoma

1990–1999

Progress Against Lymphoma

1990–19991993: Mantle cell lymphoma recognized as a subtype of non-Hodgkin lymphoma

Progress Against Lymphoma

1990–19991990s: Research suggests a therapeutic vaccine for follicular lymphoma could be possible

1995: Lymphocyte transfusions re-induce leukemia remissions

1995: Bone marrow transplantation improves survival for relapsed non-Hodgkin lymphoma

Progress Against Lymphoma

1990–19991997: FDA approves first-ever targeted cancer drug, rituximab

1997: Classification system established for non-Hodgkin lymphoma

Progress Against Lymphoma

1990–19991998: New technique enables older patients to undergo life-saving stem cell transplants

Progress Against Lymphoma

2000–Present

Progress Against Lymphoma

2000–Present2001: Scientists discover that common type of lymphoma is two distinct diseases

Progress Against Lymphoma

2000–Present2002: Adding rituximab to ''CHOP'' chemotherapy boosts survival

2002: Radioimmunotherapy introduced to treat lymphoma

Progress Against Lymphoma

2000–Present2005: Bortezomib shrinks tumors in mantle cell lymphoma

Progress Against Lymphoma

2000–Present2007: PET scanning helps guide lymphoma treatment

Progress Against Lymphoma

2000–Present2008: First drug approved specifically for T-cell lymphoma treatment

Progress Against Lymphoma

Five-Year Survival

42

47

52

57

62

67

72

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute

Progress Against Lymphoma

Mortality

4

5

6

7

8

9

10

11

12

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Progress Against Lymphoma

New Cases

11

13

15

17

19

21

23

25

27

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

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