Date post: | 17-Dec-2015 |
Category: |
Documents |
Upload: | edmund-lane |
View: | 220 times |
Download: | 0 times |
Overview
Disease Definition Epidemiological Classification Symptoms
Disease Burden Incidence Mortality Health Services
Who? Geographical Distribution
Disease Definition
Prostate cancer is a malignant tumour of the prostate
ICD 10 Code C61 / ICD9 185 Most common cancer in men in Western
countries Aetiology of the disease is not well known
Symptoms
The same as for BPHDifficulty urinating / Increased need to urinateBlood in the Urine
Often no symptoms until metastatic disease occurs
Incidence & Mortality
Source: Cancer Research UK
0
20
40
60
80
100
120
1975
1977
1979
1981
1983
1985
1987
1989
1991
1993
1995
1997
1999
2001
2003
2005
Year of diagnosis/death
incidence mortality
Age standardised (European) incidence and mortality rates, prostate cancer, males, GB, 1975-2005
Ra
te p
er
10
00
00
po
pu
lati
on
Regional Variations
Wales
0
20
40
60
80
100
120
140
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Rate
Northern Ireland
0.0
10.0
20.0
30.0
40.0
50.0
60.0
70.0
80.0
90.0
100.0
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Rate
Scotland
-
10.0
20.0
30.0
40.0
50.0
60.0
70.0
80.0
90.0
100.0
Rate
England
0
20
40
60
80
100
120
Rate
Sources: Welsh Cancer Intelligence & Surveillance Unit, IDS Scotland, National Statistics, Northern Ireland Cancer Registry
England 1993 - 2005
0
20
40
60
80
100
120
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Rate
Scotland 1993 - 2004
-
10.0
20.0
30.0
40.0
50.0
60.0
70.0
80.0
90.0
100.0
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004
Rate
Impact on Health Services
All Male Genital Cancers 1998-99 to 2005-06England
0
50000
100000
150000
200000
250000
1998-99 1999-00 2000-01 2001-02 2002-03 2003-04 2004-05 2005-06
Finished Episodes Bed Days
Source: http://www.hesonline.nhs.uk
Impact on Health Services
Prescription Costs for England 2005
Prostate Cancer and Gonadorelin Analogues 625100 prescription items dispensed £126,375,600
Source: Health and Social Care Information Centre
Population Details
Age Prostate Cancer is
a disease of older people
Some estimate that if you live until you’re 90, 90% of men will have prostate cancer Source: Cancer Research UK
0
1,000
2,000
3,000
4,000
5,000
6,000
7,000
8,000
0-4
5-9
10
-14
15
-19
20
-24
25
-29
30
-34
35
-39
40
-44
45
-49
50
-54
55
-59
60
-64
65
-69
70
-74
75
-79
80
-84
85
+
Age at diagnosis
Nu
mb
er
of
ca
se
s
0
200
400
600
800
1,000
Ra
te p
er
10
0,0
00
po
pu
lati
on
Male cases Male rates
Numbers of new cases and age specific incidence rates UK 2004
Population Details
Socioeconomic status
Incidence rates higher in more affluent menSurvival rates higher in more affluent menDifficult to identify socioeconomic status from
figures
Population Details
EthnicityDifficult to ascertain but some ethnic groups
appear to be more susceptibleWithin the USA, African-Americans have a
higher rate than Caucasian AmericansMigrants moving from low risk to high risk
areas acquire the local incidence rate
Data Quality
Main Data SourcesCancer RegistriesOffice of National StatisticsHospital Episode StatisticsPrescription Cost Analysis
Data Quality
Cancer RegistriesSystematic collection of data to assist in the
management of diseaseCore data collected with optional categoriesCore data does not include ethnicity and has
markers of socioeconomic status which could be contentious
Death certification
Data Quality
Office for National Statistics Gets data from Cancer Registries and Hospital
Episode Statistics Hospital Episode Statistics
Combines cancers of the male genital organs and so includes testicular and penile cancers
Prescription Cost Analysis Useful for costing the burden of disease No geographical variations
References Cancer Research UK http://info.cancerresearchuk.org/cancerstats/types/prostate/?a=5441
Acessed 14th April 2008 Eurostat Atlas of Mortality in the European Union 2002 Luxembourg Ferlay, J. Autier, P. Boniol, M. Heanue, M. and Boyle, P. Estimates of the cancer incidence and
mortality in Europe in 2006 Annals of Oncology (2007) 18 p581-592 Health and Social Care Information Centre Prescription Cost Analysis England 2006 London
2007 Hsing, A. Tsao, L and Devesa, S. International Trends and Patterns of Prostate Cancer Incidence
and Mortality International Journal of Cancer (2000) 85, pp60-70 Jarup, L. Best, N. Toledano, M. Wakelfield, J. and Elliot, P. Geographical Epidemiology of
Prostate Cancer in Great Britain International Journal of Cancer (2002) 97 pp695-699 Office for National Statistics Cancer Statistics Series MB1 No 36 (2007) Office for National Statistics Mortality Statistics Series DH2 No 32 (2005) Quinn, M. Moller, H. Cancer Atlas of the UK and Ireland (200 Selley S, Donovan J, Faulkner A, Coast J, Gillatt D. Diagnosis, management and screening of
early localised prostate cancer. Health Technol Assess 1997;1 (2). The Information Centre Hospital Episode Statistics http://hesonline.nhs.uk 1999 to 2007