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instance of bromide rash. One of the first cases he saw wasthat of an infant, sent to him by Dr. Glover, whose motherwas taking the bromide whilst suckling her child. The rashwas perfectly characteristic. He had now seen several casesof it. He maintained that it was sometimes mistaken fora syphilitic eruption, and he had had patients sent to him,on that supposition, when the rash was really produced bythe iodide prescribed. In the case both of the iodide andthe bromide the eruption was produced by a follicular in-flammation. There was evidently some idiosyncrasy in thepatient; for it always appeared in such cases whenever thedrug was given, and even after very small doses. He thoughtthe eruption was most extensive when the two salts weregiven in combination.-The PRESIDENT hoped the Societywould be enabled to see Dr. Crocker’s patient at a laterstage of the eruption.-Dr. GLOVER related the case re-

ferred to by Dr. T. Fox. The child was about six or eightweeks old when the rash appeared. Dr. Fox, seeing theeruption, asked whether the child were taking bromide ofpotassium. The child was not taking it, but the mother,who was suckling it, was. She was an epileptic, and hadtaken the bromide for three years. When it was left off, theeruption in the infant disappeared.-Mr. HUTCHINSON per-fectly concurred in the diagnosis of the case exhibited. Hehad seen many worse eruptions than that produced bythe iodide ; and some patients at the London Hospital werefrequently coming again with recurrences of their eruptions.It was not a question of dose, but one of idiosyncrasy. Thepatient was liable to the eruption every time he took thedrug. - Mr. NUNN said the only case he had ever seen inwhich a patient was supposed to have had an eruption dueto iodide was that of a patient in whom the rash developedwhile in the hospital, but never when out of it. - Mr.MORRANT BAKER had not the slightest doubt this was abromide rash. He suggested that the absence of bromine oriodine in the urine might point to the eruption being due toan imperfect elimination of the drug. - Dr. MAHOMED, inconfirmation of this, said that a well-marked instance ofiodide rash occurred in a patient of Dr. Broadbent’s, who diedfrom Bright’s disease. The patient shown by Dr. Crockerwas also no doubt the subject of granular kidney. - Dr.CROCKER said that whoever had seen the eruption admitted

its production by bromide and its relation to acne. The rashcould be traced from the common form of acne indurataup to such a case as the present. It was very rare inadults. No doubt there was much in idiosyncrasy ; but theFrench cases seemed to show there was also something in dose.Voisin described no fewer than five kinds of bromide eruption,and said it occurred in six out of ninety-six cases treated bythe drug. In Dr. Lees’ case some bromine was detected inthe urine, but in neither of his own cases had it been found.Bromine could not be easily detected in presence of urea.He promised to bring the patient again before the Society,but remarked that the rash does not disappear rapidly.Mr. NuNN read notes of two cases of Cancer of the

Breast. He said that in 1872 he had brought two similarcases before the notice of the Society, in one case the diseaselasting eight years, and in the other twelve months. Hehad contrasted them, and had endeavoured to answer thequestion why the one was stationary and the other so rapidin its progress. The first case he now read was that of awoman forty-five years of age, admitted into the MiddlesexHospital in February, 1877, with the right mamma enlarged,hard, and smooth ; the skin over it was natural, but tense ;the nipple was not retracted. There was not much tender-ness. No family history of cancer, and she dated the en-largement of the breast from a blow inflicted six weeksbefore her admission, followed a week later by the appear-ance of a swelling at the lower part of the organ. No effectwas produced by the application of mercurial inunction,belladonna, &c., and an exploratory puncture did not yieldany result. However, by April 8th, the organ began toulcerate, and soon the right upper limb became oodematous,the anasarca commencing in the region of the breast, andextending peripherally. The patient died on July 14th,barely six months after the onset of the disease. The breastand surrounding tissues were infiltrated with cancer, as

were also the axillary glands on both sides. There wascancer of the pleura, and effusion into the sac. Thesecond case was that of a woman seventy-two yearsold, admitted into hospital on Nov. 12th, 1873, havingnoticed a swelling in the right breast for two years. Therewere no enlarged glands. The patient was small andshrivelled in aspect ; she declined operative interference, and

has now been under observation upwards of four years. Atone time the tumour inflamed, and then an axillary glandenlarged. In April, 1877, and again in January, 1878, por-tions of the growth sloughed. Mr. Nunn thought the rapidprogress of the first case might be explained by believingthat there the lymph-canalicular system was specially at-tacked. H. Arnott relates a case of a patient aged sixty, inwhom lymphatic glandular enlargement occurred within amonth of the appearance of a sore on the lip, and in twomonths the enlargement of the glands had reached theclavicle. The brawny swelling of the arm in the presentcase was not due to pressure on the veins ; but, spreadingfrom above, it was of grave importance, and denoted the in-vasion of the lymph channels by the cancer. The second caseshows how an inflammatory attack in the affected breastmay be followed by enlargement of axillary glands. Itwas important, therefore, to protect the breast from violence,and to give tonics to fortify the system against inflammatoryattacks. Mr. Nunn referred to the statistics of Messrs. Sibleyand Baker upon the average duration of life in cancer undervarying circumstances.—Dr. GLOVER thought the questionof the duration of life in cancer one worthy of inquiry. Onecase, now under his care, had lasted for fourteen years ; anda case of gastric tumour of twenty years’ duration had latelybeen published.-Mr. MAUNDER, regretting that there wasno time for discussion, hoped that surgeons would not followMr. Nunn’s example, and watch a cancerous tumour forweeks without attempting its removal.Mr. CALLENDER exhibited some specimens of Tendon

Ligatures, which had been obtained from Dr. Girdlestone,of Melbourne, through the kindness of Mr. Hulme, ofGuildford. They were from the tail of the kangaroo,and were preferable to the catgut ligature, in their angularform, allowing of their being tied securely, the knots notslipping, and their solution does not take place so rapidly asthe catgut. In Melbourne they were much used as sutures,but, as the supply of kangaroo tails was limited, Mr.Callender had proposed to obtain ligatures from the tendonsof the tails of horses. He was having some ligatures pre-pared, and would state his experience of them at a futuretime.The Society then adjourned.

PROVINCIAL MEDICAL SOCIETIES.

BRADFORD MEDICO-CHIRURGICAL SOCIETY. -At the

January meeting, the President, R. R. Meade, Esq., in thechair, Mr. WHALLEY exhibited a Multilocular Ovarian Cyst,which he had removed from a woman twenty-three yearsold. The pedicle was secured by a Spencer Wells’s clamp,and freely treated with perchloride of iron ; the abdomenclosed with silk sutures, and the wound dressed with drylint. Menstruation occurred from the third to the sixth

day after operation; control over bladder regained on thefourth, and over rectum on the tenth day. The pedicleseparated on the fourteenth day. The pulse was about 100,and temperature ranged from 100° to 102° F., falling to

normal nine days after the operation.-Drs. Bell, Goyder,and Mossop discussed the case.-The President said thesecases did better in private than in hospital practice, andpointed out that much was due to deliberation, strict atten-tion to particulars, pure air, and assiduous after-attention.-Dr. RABAGLIATI read a paper on Antiseptic Surgery, inwhich, after giving details of antiseptic management andthe modifications of treatment in cases of abscess, operationson parts where the skin is unbroken, accidental wounds,operations through parts affected with putrid sinuses andabscesses threatening fistula in ano, he illustrated the sub-ject from cases under his care at Bradford Infirmary andfrom Professor Volkmann’s clinic at Halle. The followingconclusions were drawn :-(1) The results are such as towarrant a fair and patient trial on the part of everysurgeon; (2) the treatment is specially, useful in chronicabscess dependent on caries of bone, and in cases wherejoints have to be laid open, and not to try it in such casesseems almost criminal; (3) in compound fractures; (4) inamputations, as a preventive to pyaemia. He characterisedthe antiseptic method as one of the most useful improvementsin modern surgery.-In the discussion, Dr. Bell and Mr.

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Whalley contended that as much success attended careful muscular fibres were granular, many of them wasted, andsurgery without antiseptics as with them.-The President the intennuscular septa generally thickened. No evidencethought the treatment still sub judice, exclusion of air bein of syphilis was observed in the body, but the characters ofthe main thing aimed at.-Messrs. Aston, Goyder, and the growth were consistent only with those of new growthMossop concurred in the value of antiseptics, the latter con- of syphilitic origin.sidering that the resistance and influence of disease germs CARDIFF MEDICAL SOCIETY.-The annual meeting washad been set at rest by Pasteur and Lister.-Dr. Rabagliati, held at the Infirmary Board-room, on the 31st ult. ; R. F.in reply, contended that Lister had shown that air was Nell, Esq., in the chair. The report of the committee wasinnocuous to wounds if purified from germs. The Aber- xead, and the following officers elected to serve for the yearnethian method of treating psoas abscess failed if the 1878 :-President, Dr. Edwards. Viee-President, A. P.abscess refilled and burst, which it was almost certain to do, Fiddian, M.B. Hon. Secretary and Treasurer, Dr. Sheen.and Lister’s plan, while offering better results, secured the Committee : G. Evans, M.D., James Milward, Esq., H. J.broken-down constitution from greater evils, and afforded Paine, M.D., and William Price, M.B.opportunity for improving the general health. Mr. Spence, EDINBURGH MEDICO-CHIRURGICAL SOCIETY.—The thirdthough an opponent of Lister’s, had, in the last edition of meeting of the fifteenth session was held on the 16th ult. ;his Surgery, recommended the antiseptic treatment in cer- Dr. Gillespie, President, in the chair.-Professor GRAINGERtain cases where his own failed. STEW ART exhibited four patients illustrating in a markedBRISTOL MEDICO-CHIRURGICAL SOCIETY.-At the last degree the varying amount of Tendon Irritability in different

meeting, on Jan. 23rd, Mr. DOBSON showed a specimen of forms of Paralysis. Case 1, a little boy suffering from hemi.Fibrous Anchylosis of Tibia and Os Calcis, eleven years plegia. Tapping ligamentum patellae of the healthy jointafter excision of the astragalus. The foot had been recently with a percussion-hammer, the foot was jerked forward ; onamputated for disease of the lower part of the tibia. He the affected side, movements more violent. The normal irrita-also showed two specimens of Exostosis-(l) of the cancel- ’bility was wholly lost in locomotor ataxy, and this was onelous variety, from a patient nineteen years of age, from epi- of the earliest and most reliable signs of the disease. Case 2,physial cartilage at upper end of tibia ; (2) a tumour, the locomotor ataxy ; absolutely no response to tapping thesize of an orange, from the internal malleolus of a young patellar tendon. Ordinary reflex movements not impaired.man, aged twenty-four. The growth consisted of dense Case 3, with some ataxic features, but showing excessiveivory bone, traversed by bands of fibrous and spindle-celled tendon-irritability. Case 4;, well-marked ataxy; no irrita-tissue. The patient died six or eight months after from bility of tendon. - Mr. JOSEPH BELL showed a case ofheemoptysis.—Dr. MARKHAM SKERRITT read notes of a case Amputation at Hip-joint for a large sarcoma of the thigh.-of Subcutaneous Emphysema and Infiltration with pus fol- Professor ANNANDALE showed a case of Reflex Paraplegialowing Aspiration for Pyo-pneumothorax. The patient, a ’in a boy (no affection of the sphinct-ers or loss of sensi-woman, aged twenty-three, was admitted into the Bristol bility), markedly improved by circumcision of a tightGeneral Hospital with a history of some acute chest attack prepuce. He also showed a case of compound separa-about a year previously, leaving persistent dyspnoea and .tion of lower epiphysis of left radius and ulna,cough. The physical signs were those of fluid and air in with detachment of periosteum. One inch and a halfthe left pleura, and of bronchitis and dry pleurisy in the of the bare bones, along with the epiphysis, were re-

right side. Aspiration was performed in consequence of the moved, and a useful movable hand was the result.-dyspnoea, and about two and a quarter pints of fetid pus Dr. GILLESPIE, in retiring from the chair, delivered his vale-and gas withdrawn from the left pleura. On the second dictory address, in the course of which he alluded in feelingday after, extensive subcutaneous emphysema was de- terms to the loss the Society had sustained by the deaths oftected over the back and loins, with evidence, also, Dr. Warburton Begbie and Dr. Brotherton, of Alloa, and byof the escape of pus into the areolar tissue. A free the removal to London of two eminent members of theopening was made into the pleural cavity, and a Society, Professor Lister and Dr. Matthews Duncan. Thedrainage-tube inserted, but the patient died in about six chair was then taken by the new President, Professorhours. The post-mortem showed extensive infiltration of Sanders. Among the pathological specimens exhibited, Dr.the areolar tissue with pus and gas; the lung was collapsed ARGYLL ROBERTSON showed a Scirrhous Tumour of theand bound down by old false membrane; no communication Orbit which had displaced the eye upwards and outwards. Itfound between lung and pleural sac; recent pleurisy on right was removed, leaving the eye.-Mr. GEORGE BELL showedside, with cedema and congestion of lung. Dr. Skerritt two Tumours of the Breast, one scirrhous, with epithelialbelieved the pneumothorax arose from decomposition in an cancer of the nipple, the other sarcomatous. The woundsold empyema, and drew attention to the remarkable, if not had been treated by long drainage-tubes, coming throughunique, accident which had followed aspiration. He also the antiseptic gauze dressing, and leading into a vesselshowed a specimen of Fusiform Aneurism of the Aorta, in- under the bed containing carbolic acid. The results

volving the vessel from its commencement to beyond the were very good. The first case was only ten days in

origin of the left subelavian.-Dr. G. GREIG-SMITH ex- ’hospital. In the second, there was no discharge on thehibited a specimen of Haemorrhage into the Medulla dressing.-Dr. KIRK DUNCANNON showed a skull with aOblongata. The patient, a man aged forty-eight, continued knitting-needle inserted through the orbit, showing the pro-sensible for nearly two hours before coma supervened. The bable course such an instrument would take in a case wheresymptoms were: left facial paralysis; imperfect paralysis, the brain remained uninjured.-Dr. CHURCH showed a largewith persistent endeavours to flex the right limbs; deaf- ,Salivary Calculus.-Dr. BYROM BRAMWELL (Newcastle-on-ness ; speechlessness; contracted pupils; no strabismus; no Tyne) read a paper, "Notes on Cases of Aneurism, indysphagia; no anaesthesia. Death occurred six hours after which he described the physical signs, symptoms, and treat-the attack. Post-mortem: Extreme emphysema ; hyper- ment of six cases of aortic and one of innominate aneurism,trophy of heart, and very atheromatous cerebral vessels; the besides three others which did not occur in his own practice.haemorrhage distended the fourth ventricle, and caused a In the fatal cases the mode of death was detailed, and pre-deep transverse rent in the upper part of the medulla, and parations of the aneurisms exhibited. Great benefit was pro-some superficial laceration of the floor of the ventricle duced in most of the cases by half-drachm doses of iodide ofDr. SHINGLETON SMITH exhibited an almost unique specimen potassium.-Prof. Stewart remarked on the interest of theof Syphiloma of the Heart, from a woman aged about thirty- cases and the highly satisfactory nature of the treatment byfive, who had fallen dead in the street, with no history of iodide of potassium in large doses, which had been intro.previous illness. A growth was found to have invaded the duced by Dr. G. W. Balfour.-After a few remarks from Dr.heart-muscle, but very unequally. On the left ventricular Black on the frequency of aneurism among soldiers and thesurface pale nodules were visible, extending to half an inch influence of alcohol in causing the disease, Dr. Bramwellin depth; projecting internally were many other nodules as replied.large as peas, growing in the muscular columns; the greater ——

portion of the inter-ventricular septum was uniformly in- ..filtrated, being pale in colour, and apparently having little SMALL-POX IN DUBLIN.—ims disease appears tomuscle structure remaining. Microscopically the nodules be increasing in Dublin, one hospital having twenty-eightwere found to consist of a coarse fibrous stroma, resembling cases under ’treatment, twenty of which had been admittedthe normal stroma of the heart, but much thickened, and uni- in one week. The Managing Committee of the Cork-streetversally infiltrated with a very abundant small-celled Fever Hospital have directed that an additional ward begrowth. Elsewhere the small nuclear growth was found to set apart for the epidemic, and that the recovery-houseinfiltrate the muscle structure in all possible degrees. The be cleared for the use of convalescent small-pox patients.