18
PRPPsynthetase
Nucleosidephosphorylases
Phosphoribosyltransferases
The committed step of de novo purine nucleotide biosynthesis
Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition
Outline of de novo purinenucleotide biosynthesis
Outline of de novo pyrimidine nucleotide biosynthesis
EnzymesI. Ribonucleotide reductaseII. Nucleotide diphosphate kinaseIII. dCMP kinaseIV. dUTP diphosphohydrolaseV. dCMP deaminaseVI. Thymidylate synthaseVII. FH2 reductase
