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The Pediatric Scientist Development Program under the aegis of AMSPDC
The Pediatric Scientist Development Program
under the aegis ofAMSPDC
Goals of the PSDP
• To provide pediatricians with an intensive research experience in basic, translational, or clinical/epidemiologic science applicable to diseases of childhood.
• To enlarge the cadre of NIH- or CIHR-funded pediatricians in US and Canadian departments.
• To nurture the next generation of academic pediatricians throughout North America.
PSDP Funding Consortium
• NICHD
• American Pediatric Society
• American Academy of Pediatrics
• March of Dimes
• Paediatric Chairs of Canada
• Sick Kids Foundation
• St. Jude Children’s Research Hospital
PSDP Eligibility Criteria
• U.S. citizen, permanent resident, or Canadian citizen
• M.D. (target group) or M.D./ Ph.D.
• Committed to basic, translational, or clinical research relevant to pediatrics in an investigative setting with a senior mentor
• Dedicated to a career in academic pediatrics
• Application 17 months prior to the start of the PSDP-sponsored research component
Timelines for PSDP Application STANDARD TIMELINE
PSDP year 3
Feb 1- application
PSDP year 1
12-monthclinicalfellowship
PL-3 year
Nov 1- identify
PSDP year 2
17 months
PSDP year 3
Feb 1- application
PSDP year 1
Nov 1- identify
PSDP year 2
17 monthsFellow year 2
Fellow year 1
CARDIOLOGY, CRITICAL CARE, PEM, NEONATOLOGY
Nominating States and Programs
02468
101214161820
19971999
20012003
20052007
2009
StatesPrograms
34 Nominating Programs
64 Homes of 120 Graduates
Applicants
0
5
10
15
20
25
Applicants# Males#MD, PhD
4
Clinical Responsibilities
• Steering Committee reaffirms the principle of
no clinical responsibilities in years 1 and 2 of PSDP-sponsored research
• 15% clinical time allowed in year 3• Applicants to train in patient-oriented investigation
(clinical or translational) - option for 10% clinical time– how the clinical time is to be spent
– what is the population to be seen
– why the clinical time is essential to the research project
Salary Scale
• First year - cap of $65,000 + 15% fringe– $20,000 supplies
• Second year - cap of $70,000 + 15% fringe– $20,000 supplies
• Third year - cap of $75,000 + 15% fringe– $20,000 supplies
• Eligible to apply to the NIH Loan Repayment Program
NICHD Loan Repayment Program http://www.lrp.nih.gov/
• Eligibility– U.S. citizen or permanent resident– Performing research relevant to pediatrics
(sponsored by NIH or non-profit)– Accrued debt constitutes >20% of income
• Payments – Quarterly reimbursement of loans and interest up
to $35,000 annually for two years DIRECT to lender PLUS quarterly tax payments to IRS
0
10
20
30
40
50
K02 K08 K24 R29 R03 R21 R01 R41 R55 P01 P50 U01
123 NIH Grants Trainees Graduating 1988-2008
Recent PSDP Grants
Fellow Nominating
Department
Sponsoring
Department
Current
Department
Grants
C. Gale ‘96 U MN U MN U MN R01
B. Gomperts ‘00 Wash U Wash U UCLA R01
D. Ingram ‘01 U IN U IN U IN P50
M.Khokha ‘02 Wash U UCSF Yale 2 R01s
S. Wu ‘02 UCLA UCLA UCLA R21
T. Lu ‘03 U Penn UCSF Cornell R01
D. Hunstad ‘04 Wash U Wash U Wash U R03
PSDP* Funding Rate at NIH vs. Other MD’s
0
10
20
30
40
50
60
All PSDP traineesAll PSDP appliedPSDP R seriesPSDP R-01Overall NIH Success
*Fellows entering 1987-2007 **Zerhouni EA. Science:314:1088, 2006
Perc
ent
**
Subspecialties in PSDP
0
2
4
6
8
10
12
14
16
18
Subspecialty
Inf DisNeoCritical CareHeme/OncGIAll/Imm/RheuCardiologyNephrologyEndoGeneticsPulmonologyDevel/BehavGenl PedsNeuroInformatics
Per
cent
Role of AMSPDC
• FIS CHAIR– bring a resident to AMSPDC– women, minorities, underserved subspecialties
• NOMINATING CHAIR– chair at the institution from which the candidate applies– helps the candidate to select potential mentors
• SPONSORING CHAIR– chair at the institution where the candidate will be trained– helps the candidate to select potential mentors– guarantees the candidate the protected time to complete the proposed
program in basic, translational, or clinical research– serves as a career mentor to help in transition from fellowship to
faculty
Role of AMSPDC:PSDP Committees
• STEERING COMMITTEE– AMSPDC representatives– Funding agency representatives: AAP, APS, MOD, Sick Kids,
St. Jude’s
• PROGRAM EVALUATION COMMITTEE– APS representatives– SPR representatives– NICHD representatives
• SELECTION COMMITTEE– AMSPDC representatives– Basic and clinical science representatives– Steering Committee representatives
Benefits to AMSPDC Chairs
• Faculty recruitment• Enhancement of your department’s strengths
in clinical, translational, or basic research– liaison with other depts.– well-trained faculty member
• Contributing to the continental network of pediatric physician-scientists
• Nurturing the next generation of academic pediatricians
PSDP Excludes
• People who are not U.S. or Canadian citizens
• People who are not pediatricians• People who have only the Ph.D. degree
New Initiative: Timing of Application
• Application as PL3 or PL4 for those sub-specialties requiring 1 year of clinical training– endocrinology, infectious diseases, pulmonology
• Application as a first-year fellow for those sub- specialties requiring 13-24 months of clinical training– cardiology, critical care, PEM, neonatology
• Must have letter from fellowship director stating the duration of clinical training
Applicants Proposing Patient-Oriented Investigation
• For those applicants training in patient-oriented investigation (clinical or translational), an option for 10% clinical time will be considered, provided that the grant proposal details explicitly– how the clinical time is to be spent– what is the population to be seen – why the clinical time is essential to the research project
• What is 10% clinical time?– 1/2-day in clinic a week– 2 weeks ICU time in 1-week blocks
0
10
20
30
40
50
60
70
80
90
100
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
% of Applicants
% Selected
Pe
rce
nt
Women in the PSDP
K08 by Year of Graduation
0
10
20
30
40
50
60
70
80
90
100
2000 2001 2002 2003 2004 2005 2006 2007 2008
3-D Column 1
Perc
ent
