PATHOLOGY EXAMINATIONDepartment of PathologyMedicine Faculty Brawijaya University

?DIAGNOSISHISTORY TAKINGPHYS EXAMLAB EXAMR EXAMPA EXAMTHERAPY

Anatomic Pathology Examinations Histopathologic Ex. - HistoPA routine Frozensection(Vries Coupe) - Pathology autopsyCytologic Ex. - Exfoliative Cytl :Gyn and non gyn - FNAB

Histopathology ExaminationSpecimen from operation ( mastectomy, TAH BSO, appendectomy ,colon resection, nephrectomy, thyroidectomy etc .Excisional biopsy ( FAM, polyp < 3 cm)Incisional biopsy ( tumors > 3 cm ).Curretage ( from uterus , dentigerous cyst, etc )TURP, TURBAutopsy specimens.

PreparationComplete delivery form : patient identity, specimen type, fixation, location, clinical diagnosis, complete clinical information + draw location and size of tumor, history of the disease and lab examination.Fixation with 10 % formalin.Specimen label : name, regist number.

Receive specimens from patient

Frozen Section

Durante op ,Without fixation.From : ovary tumor, breast tumor, thyroid tumor, skin tumor, brain tumor, Hirschsprung disease.Decided benign or malignant, free margins Operation technic ( therapy management).GOLD STANDARD DX : histopathology paraffin block

FINE NEEDLE ASPIRATION BIOPSY

Role of FNABDifferentiate : non neoplastic and neoplastic lesionDifferentiate : benign and malignant tumorDifferentiate Malignant tumors : primary, metastatic, or recurrence.Rapid diagnosis for emergency case :spinal lesion with cord compression.Determine staging of tumor.

Close biopsy with FNABSimple , economical technique.Can be performed as an outpatient procedure.Few complications.Multiple sites.Rapid diagnosis & treatment planningHighly accurate

FNAB ProcedurePRECONDITIONClinical information.Conventional radiograph / CT scan / MRI /USG of the tumorBiopsy target can be located with palpation or guided by CT scan/ USG.

Material and MethodNeedle 25 G/27 G/23GSpuit 10cc.Object glass.Alcohol 70 %Alcohol 95%.

1. Examine patient and Radiograph

2. Puncture TumorDesinfection.Tumor fixation with fingers.Puncture tumor without/with aspiration.

Make smear-fixation-staining

FNAB diagnostic : GCT of the Bone

Thank you for your attention

Faktor, resiko, tulis nama dengan benar (tulisan yang jelas !)** ketebalan 3-5 um*